Medicine and Health Sciences Commons^™

2013 Program, Office Of Academic Affairs

Programs

At its best, a university is a collection of individuals ‐‐ students and faculty ‐‐ focused on learning and discovering new knowledge. For this goal to be realized, a critical element is having faculty members deeply engaged with their disciplines. Scholarship, in the form of journal articles, book chapters, monographs and similar endeavors, creative activity which can take an even wider range of forms, and funded research which explores the boundaries of their disciplines all contribute to such engagement. Through such participation, faculty members stay at the growing edges of their fields, and in so doing, they enrich their intellectual …

Assessing Current Awareness And Behaviors Of Those At Risk For Multiple Sclerosis, Kristin A. Prusse, Dr. Michael Barnes

Journal of Undergraduate Research

Multiple Sclerosis (MS) is an inflammatory autoimmune disorder of the central nervous system. Multiple sclerosis is characterized by the destruction of the myelin sheath, which surrounds and insulates the nerve fibers in the brain and spinal cord. This destruction forms plaques of damaged tissue in the brain causing nerve impulses to be slowed or halted. MS is now the most common cause of neurological disability in young adults. However, in many cases, this disease goes misdiagnosed for several years, which delays treatments that can help manage symptoms and slow the progression of the disease. It then becomes important for those …

Identifying Barriers To Patient Recruitment In Community Randomized Clinical Trials, Evan L. Thacker, Dr. Ray M. Merrill

Journal of Undergraduate Research

Randomized clinical trials (RCTs) are the final testing phase for new medical procedures or treatments in human subjects. A common problem in community-based RCTs is low participation. Researchers have sought to identify barriers to RCT recruitment by measuring knowledge and attitudes about RCTs. Most studies focus on subjects already involved in clinical trials or subjects who were invited to participate in clinical trials but declined. Our research addresses recruitment barriers in a broader context, by studying knowledge and attitudes among the general public, including individuals who have never participated in a RCT.

Alcohol Advertising Codes: A Need For Reform, Rachel Ekman, Dr. Gordon Lindsay

Journal of Undergraduate Research

In the United States, the alcohol industry is made up of three major trade associations: The Beer Institute, The Wine Institute, and Distilled Spirits Council of the United States (DISCUS). These three associations are responsible for governing their own product advertisements. To do this, each has developed a set of standards or voluntary codes, which they are to follow and regulate.

Determining The Tobacco Industry’S Influence On Health Legislation, Jordana R. Choucair, Dr. Michael Barnes

Journal of Undergraduate Research

Each year, 440,000 American lives are claimed by smoking-related diseases.1 The economic costs of smoking are astronomical. Smoking costs the United States over $150 billion each year in health-care costs including $81.9 billion in mortality-related productivity loses and $75.5 billion in excess medical expenditures.2 Furthermore, secondhand smoke is responsible for approximately 3,000 lung cancer deaths annually in U.S. nonsmokers.3 However, tobacco does not only affect those who smoke and inhale cigarette carcinogens, tobacco affects all Americans due to the influence the tobacco industry has in politics.

Ua3/9/7 Cancer Study, Wku President's Office - Ransdell

WKU Administration Documents

Email from WKU president Gary Ransdell to faculty & staff regarding cancer research.

Severe Mental Illness In Adults And Physical Health Outcomes, Kathryn L. Speeter

Doctoral Projects

Adults with severe mental illness (SMI) experience higher morbidity and mortality rates than the general population due to poor physical health and because physical and psychiatric health are rarely addressed holistically. Two questions were posed for this project: (a) Will the use of a physical health screening tool and development of healthpromotion goals result in a change in healthy lifestyle behaviors for participants? (b) Will case managers see value in the use of the screening tool and health-promotion action plan development and incorporate the tool into their day-to-day work with clients? Fourteen adults with SMI, from a community case management …

Health Workforce Needs: Projections Complicated By Practice And Technology Changes, Rob Cunningham

National Health Policy Forum

As population growth and the aging of the overall population increase demand for health care, policymakers and analysts posit whether sufficient health care providers will be able to meet that demand. Some argue there are too few providers already; others say our current supply-demand problems lie with efficiency. But suppose both are correct? Perhaps the real challenge is to understand how physician practices are changing in response to market forces such as payment changes, provider distributions, and technology innovations. This issue brief reviews what is known about evolving practice organizations, professional mixes, information technology support, and the implications of these …

Generalizing Anxiety, Center For Public Service

SURGE

As she began reading the list of symptoms, I was making mental check marks next to the ones that applied to me.

Fear of interacting with strangers- check. Fear that others will notice that you look anxious- check. Avoiding doing things or talking to people out of fear of embarrassment- check. Fear of situations in which you may be judged- check. Anxiety that disrupts your daily routine, work or school activities- check, check, check. [excerpt]

What's Happening: October 21, 2013, Maine Medical Center

What's Happening

No abstract provided.

Today - October 21, 2013, Loma Linda University Health

TODAY

Inside this issue:

-- Latest installment of $3 million gift from San Manuel enables Cancer Center to build biospecimen lab
-- Concrete pour moves Centennial overpass closer to completion
-- School of Dentistry alumnus appointed director of educational assessment
-- Free party for community planned for Children's Hospital 20th anniversary
-- Nine-year-old patient appeals to radiothon listeners during first public outing in 10 months
-- LLU researchers publish potential new remedy for neuropathic pain
-- Wholeness and holiness in health: School of Religion hosts Ontario clergy at convocation
-- Family health fair to include 5K, health screenings, and fun
-- …

Ada News - 10/21/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Application Of Flexible Bronchoscopy In Inhalation Lung Injury, Chong Bai, Haidong Huang, Xiaopeng Yao, Shihui Zhu, Bing Li, Jingqing Hang, Wei Zhang, Paul Zarogoulidis, Andreas Gschwendtner, Konstantinos Zarogoulidis, Qiang Li, Michael Simoff

Internal Medicine Faculty Publications

Background: As acute inhalational injury is an uncommon presentation to most institutions, a standard approach to its assessment and management, especially using flexible bronchoscopy, has not received significant attention. Methods: The objective of this study is to evaluate the value of using flexible bronchoscopy as part of the evaluation and management of patients with inhalational lung injury. Twenty-three cases of inhalational lung injury were treated in our three hospitals after a fire in a residential building. The twenty cases that underwent bronchoscopy as part of their management are included in this analysis. After admission, the first bronchoscopy was conducted within …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Effectiveness of Mass Media

Introducing A New Cadre Into Uganda’S Health Care System: Lessons Learnt From The Implementation Process, Gerald M. Amandu, Leana R. Uys, Joseph Mwizerwa, Alex Erejo, Irene A. Cheruto, Margaret Chota

School of Nursing & Midwifery, East Africa

Uganda introduced Registered Comprehensive Nursing (RCN) and Enrolled Comprehensive Nursing (ECN) training programs in 1994 and 2003 respectively, to create certificate and diploma level cadre of nurses with competencies in general nursing, midwifery, public health, psychiatry, paediatrics and management. This paper is based on an evaluation study undertaken to assess how the programs were implemented including stakeholders’ perceptions about the graduates. Despite being relevant, the implementation process of both programs failed to meet acceptable standards. We conclude that introducing a new cadre of nurses without proper preparation hinders realization of their full potential including their contribution to the healthcare system.

Health Policy & Management News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

• Effectiveness of Mass Media

Increased Risk And Related Factors Of Depression Among Patients With Copd: A Population-Based Cohort Study, Tzung-Yi Tsai, Hanoch Livneh, Ming-Chi Lu, Pang-Yau Tsai, Pei-Chun Chen, Fung-Chang Sung

Counselor Education Faculty Publications and Presentations

Background

Depression is a common and mostly undertreated problem in patients with chronic diseases. However, population-based studies on the association between chronic obstructive pulmonary disease (COPD) and subsequent depression are limited in Asian populations. This study evaluated the incidence and risk factors of depression for patients with COPD in Taiwan.

Methods

Using the claims data from the National Health Insurance of Taiwan, we identified 38,010 COPD patients newly diagnosed in 2000–2004 and 38,010 subjects without COPD frequency, matched by sex, age and index date. The incidence rate and hazard ratio for depression were estimated by the end of 2008.

Results …

The Use Of Near Infrared And Microwave Sensing For On-Line Real Time Monitoring Of Moisture Content And Composition Of Powder Blend, Ryan V. Mcdonnell, Anshu Gupta, John Austin, Michael T. Harris, Gintaras V. Reklaitis

The Summer Undergraduate Research Fellowship (SURF) Symposium

Online process analytics has been a topic of interest by pharmaceutical companies as a method of determining how operating parameters affect the final quality of their products. One form of online process analytics that has been found to be effective is microwave sensing. While it has been found that microwave resonance sensing can be used to measure parameters such as moisture content and density, it has yet to be discovered if such sensors have the ability to measure changes in content uniformity of raw materials pharmaceutical companies use. Data was collected using a spin riffler fitted with a microwave sensor …

Cellular Uptake Mechanism Of Paclitaxel Nanocrystals, Iris K. Archer, Zhaohui Wang, Tonglei Li

The Summer Undergraduate Research Fellowship (SURF) Symposium

Therapeutic options for metastasized human cancer in current practice remain limited and, sadly, there is no cure for metastatic cancer. The typical approach, chemotherapy, has both low efficacy due to poor drug solubility, and cytotoxic side effects to healthy tissue when delivered indiscriminately. To address both of these issues, we are pursuing the use of nanocrystal formulations of current chemotherapeutic agents as delivery platforms. Herein, we have studied cellular uptake mechanisms in cancer cells of nanocrystals of a chemotherapeutic agent, paclitaxel. Our goal in this study is to determine whether the nanocrystals can be taken up via endocytosis, especially when …

Investigating Intermolecular Interactions In Crystalline Aspirin Using Cdft, Nicholas Turner, Tonglei Li, Mingtao Zhang

The Summer Undergraduate Research Fellowship (SURF) Symposium

Drugs today are widely administered in their crystalline form, namely via tablets and capsules. The crystal structure of a drug molecule affects important drug qualities such as solubility, bioavailability, shelf life, and compaction properties. In order to form a basis for crystal structure prediction, it is necessary to first understand how intermolecular interactions cause molecules to pack in certain ways. Being able to predict and perhaps even control a drug molecule’s crystal structure will lead to the development of higher quality drugs that perform more consistently. Scientists and engineers do not fully understand the reasons for a molecule assuming a …

Investigation Of Major Intermolecular Interactions In 7,8-Dihydrobenzo(K)Phenanthridin-6(5h)-One Crystal Using Quantum Calculations And Crystallographic Visualization Programs, Zhiwei Liao, Tonglei Li, Mingtao Zhang

The Summer Undergraduate Research Fellowship (SURF) Symposium

Currently, tablets and capsules are the most common ways of delivering drugs. The active pharmaceutical ingredients and excipients used to make those tablets and capsules are in their crystalline form generally. However, a single molecule can form multiple different crystal structures because of different packing arrangements of the molecules. These different crystal structures have identical chemical composition but different properties such as solubility, density, stability, etc. This phenomenon is called polymorphism. Occurrence of polymorphism could be a disaster for both patients and pharmaceutical companies, as the drug could lose its efficacy due to changes in properties. Studying intermolecular interactions in …

Non-Mass Transfer Limited Crystal Growth, Ryan J. Smyth, Caitlin Schram, Stephen P. Beaudoin

The Summer Undergraduate Research Fellowship (SURF) Symposium

There are many different active pharmaceutical ingredients (APIs) that have been discovered in research labs all around the world that can be used to treat and cure patients with a variety of different ailments. The challenge with these APIs in treatments is that they are not soluble in water, thus they low absorption into the blood stream (bio-availability). The key to making these APIs more bio-available is to understand how they grow as crystals and drop out of the aqueous solutions. One of the ways these APIs were made more bio-available is to render them amorphous and suspend them in …

Direct Quantitative Analysis Of Biomarkers Using Mass Spectrometry, Morgan N. Mcluckey, Zheng Ouyang

The Summer Undergraduate Research Fellowship (SURF) Symposium

Point-of-care (POC) diagnostics describes a step in the medical treatment process where drugs can be monitored in a patient’s body on-site and in a timely fashion. Mass spectrometry (MS) can provide a quick, efficient, and highly accurate method of analysis of patient biofluids and tissues. Developing methods to bring this diagnostic mechanism to hospitals and clinics has the potential to improve patient care through, for example, personalized medicine. Our goal was to develop a way to effectively introduce internal standard (IS), a necessary chemical for the analytical process, to low-volume biofluid samples. Additionally, the effective direct quantitation of biomarkers with …

Preliminary Findings From An Interventional Study Using Network Analysis To Support Management In Local Health Departments In Florida, Chin S. Park, Hado Byon, Jonathan W. Keeling, Leslie M. Beitsch, Jacqueline A. Merrill

Frontiers in Public Health Services and Systems Research

Management is the core service that integrates and coordinates essential public health services. Managers of local health departments (LHDs) are experts in practice but may not have expertise in organizational management. We conducted an evidence-based training intervention in 10 LHDs in Florida to support managers’ decision-making on organizational integration and coordination. We deployed a standard survey to collect organizational network measurements pre and post intervention. We presented results as evidence-based performance feedback and interviewed managers to document how they used the results in the context of each organization. Post intervention we found unexpected, significantly higher network centralization in daily work. …

Characteristics Of A Local Health Department Associated With The Use Of The Health Equity Index, Moira A. Lawson, Sharon Mierzwa, Michael Knapp

Frontiers in Public Health Services and Systems Research

Local health departments are tasked with understanding and addressing health inequities in the populations they serve. To meaningfully address health inequities, local health departments have identified the need for credible local data to better understand the relationship between community conditions and health outcomes. Yet, when given access to these data, we observe a very large variation in the level of interest between local health departments.

In this study, we offered Connecticut’s Local health departments access to the Health Equity Index, a web based tool that provides data on health outcomes and community conditions at the state, municipal or neighborhood levels. …

Evaluating Use Of Custom Survey Reports By Local Health Departments, Nadya M. Belenky, Christine A. Bevc, Elizabeth Mahanna, Carol Gunther-Mohr, Mary V. Davis

Frontiers in Public Health Services and Systems Research

This report demonstrates how providing survey feedback, like comparative reports, to survey respondents can result in improvement activities. For each of the past three years (2010-2013), the North Carolina Institute for Public Health (NCIPH) has invited local health departments (LHDs) from 40 states to participate in a preparedness capacities survey. In addition, NCIPH fielded a six-question evaluation survey to a subset of LHDs (n=70) to determine how LHDs use these reports. LHDs that reported using their custom reports compared their preparedness capacities to other LHDs, conducted strategic planning (e.g., benchmarking, setting preparedness goals), planned staff trainings, and disseminated the report …

Assessing A Quality Improvement Project In A Georgia County Health Department, Dayna S. Alexander, William C. Livingood, Nandi A. Marshall, Angela Peden, Russ Toal, Gulzar H. Shah, Alesha Wright, Purity Cummings, Ketty Gonzalez, Lynn Woodhouse

Frontiers in Public Health Services and Systems Research

The study and evaluation of quality improvement among Georgia’s public health systems continues to be a major priority for the Georgia Public Health Practice Based Research Network (GAPH-PBRN). This article focuses on the application and evaluation of a Quality Improvement project in a Georgia County Health Department. The QI team sought to reduce the waiting time in the teen clinic; thereby, increasing the Quality Improvement culture one project at a time in this Health Department. The project revealed that Quality Improvement is a continuous process that requires change and adaptation by employees. This initial Quality Improvement project was the first …

The Relationship Between Quality Improvement And Health Information Technology Use In Local Health Departments, Kendra Johnson, Kim K. Nguyen, Shimin Zheng, Robin P. Pendley

Frontiers in Public Health Services and Systems Research

This research examined if there is a relationship between engagement in quality improvement (QI) and health information technology (HIT) for local health departments (LHDs) controlling for workforce, finance, population, and governance structure. This was a cross-sectional study that analyzed data obtained from the Core questions and Module 1 in the NACCHO 2010 Profile of LHDs. Descriptive statistics, bivariate analyses, and logistic regression analyses were conducted. Findings suggest that LHD engagement in QI has a relationship with utilization of HIT including electronic health records, practice management systems, and electronic syndromic surveillance systems. This study provides baseline information about the HIT use …

Commentary: The Road To Quality In Public Health, A Long But Important Journey, F. Douglas Scutchfield, Glen Mays, Marylou Wallace

Frontiers in Public Health Services and Systems Research

Quality improvement (QI) in public health departments is a focus in this sixth issue of Frontiers. Data is important to the development of quality improvement efforts. As we see growth of and meaningful use of electronic health records, the health department is in a position to take the lead as a data hub and to use this information wisely to both improve their QI efforts and link that QI to outcomes.

Probiotics: Finding The Right Regulatory Balance, Diane E. Hoffmann, Claire M. Fraser-Liggett, Frank B. Palumbo, Jacques Ravel, Karen H. Rothenberg, Virginia Rowthorn

Faculty Scholarship

Some products marketed as drugs should be excused from Phase I trials, but safety and efficacy claims for dietary supplements should be more tightly regulated.