Medicine and Health Sciences Commons^™

Use Of Inhaled Pge1 To Improve Diastolic Dysfunction, Lvedp, Pulmonary Hypertension And Hypoxia In Ards—A Randomised Clinical Trial, Shahla Siddiqui, Nawal Salahuddin, Salwa Zubair, Muniza Yousuf, Iqbal Azam, Anwar Hassan Gilani

Department of Biological & Biomedical Sciences

Introduction: We wished to see the effects of inhaled PGE1 on diastolic dysfunction, left ventricular end diastolic pressure (LVEDP), pulmonary hypertension and hypoxia in ARDS patients.
Methods: This is a randomized, prospective, clinical trial conducted in the main adult intensive care unit of a tertiary care University hospital. A total of 67 patients were recruited. Inclusion criteria included all adult patients with a P/F ratio /or Pulmonary Artery systolic (Pa) pressures of >35 mmHg on Pulmonary artery catheter or suspected on clinical grounds. A transthoracic echo was performed to record the diastolic function, LVEDP and Pa pressures. Subsequently patients were …

Trident - March 2013, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.

A University System’S Approach To Enhancing The Educational Mission Of Health Science Schools And Institutions: The University Of Texas Academy Of Health Science Education, L. Maximilian Buja, Susan M. Cox, Steven A. Lieberman, Jonathan Macclements, Janet F. Williams, Robert M. Esterl Jr., Kenneth I. Shine

Library Staff Publications

Background: The academy movement developed in the United States as an important approach to enhance the educational mission and facilitate the recognition and work of educators at medical schools and health science institutions. Objectives: Academies initially formed at individual medical schools. Educators and leaders in The University of Texas System (the UT System, UTS) recognized the academy movement as a means both to address special challenges and pursue opportunities for advancing the educational mission of academic health sciences institutions. Methods: The UTS academy process was started by the appointment of a Chancellor’s Health Fellow for Education in 2004. Subsequently, the …

Describing Teacher–Student Interactions: A Qualitative Assessment Of Teacher Implementation Of The 7th Grade Keepin’ It Real Substance Use Intervention, Jonathan Pettigrew, Michelle Miller-Day, Young Ju Shin, Michael L. Hecht, Janice L. Krieger, John W. Graham

Communication Faculty Articles and Research

Variations in the delivery of school-based substance use prevention curricula affect students' acquisition of the lesson content and program outcomes. Although adaptation is sometimes viewed as a lack of fidelity, it is unclear what types of variations actually occur in the classroom. This observational study investigated teacher and student behaviors during implementation of a middle school-based drug prevention curriculum in 25 schools across two Midwestern states. Trained observers coded videos of 276 lessons, reflecting a total of 31 predominantly Caucasian teachers (10 males and 21 females) in 73 different classes. Employing qualitative coding procedures, the study provides a working typology …

Effects Of Aging On Apoptosis Gene Expression In Oral Mucosal Tissues, Octavio A. Gonzalez, Michael John Novak, Sreenatha S. Kirakodu, Arnold J. Stromberg, Shu Shen, Luis Orraca, Janis Gonzalez-Martinez, Jeffrey L. Ebersole

Center for Oral Health Research Faculty Publications

Apoptotic processes are important for physiologic renewal of an intact epithelial barrier and contribute some antimicrobial resistance for bacteria and viruses, as well as anti-inflammatory effects that benefits the mucosa. The oral cavity presents a model of host-bacterial interactions at mucosal surfaces, in which a panoply of microorganisms colonizes various niches in the oral cavity and creates complex multispecies biofilms that challenge the gingival tissues. This report details gene expression in apoptotic pathways that occur in oral mucosal tissues across the lifespan, using a nonhuman primate model. Macaca mulatta primates from 2 to 23 years of age (n = …

Serotonergic Innervation And Serotonin Receptor Expression Of Npy-Producing Neurons In The Rat Lateral And Basolateral Amygdaloid Nuclei., M Bonn, A Schmitt, K-P Lesch, E J Van Bockstaele, E Asan

Department of Neuroscience Faculty Papers

Pharmacobehavioral studies in experimental animals, and imaging studies in humans, indicate that serotonergic transmission in the amygdala plays a key role in emotional processing, especially for anxiety-related stimuli. The lateral and basolateral amygdaloid nuclei receive a dense serotonergic innervation in all species studied to date. We investigated interrelations between serotonergic afferents and neuropeptide Y (NPY)-producing neurons, which are a subpopulation of inhibitory interneurons in the rat lateral and basolateral nuclei with particularly strong anxiolytic properties. Dual light microscopic immunolabeling showed numerous appositions of serotonergic afferents on NPY-immunoreactive somata. Using electron microscopy, direct membrane appositions and synaptic contacts between serotonin-containing axon …

Women Bound To Be Active: Differences In Long-Term Physical Activity Between Completers And Noncompleters Of A Book Club Intervention, Jennifer L. Huberty, Diane Ehlers, Jason Coleman, Yong Gao, Steriani Elavsky

Kinesiology Faculty Publications and Presentations

Background: Ideal approaches to increasing long-term physical activity (PA) adherence in women remain unclear. This study used a longitudinal mixed-methods approach to 1) determine the effectiveness of an 8-month book club intervention for increasing PA participation and self-worth, and reducing barriers at 1-year followup; and 2) identify reasons why completers and noncompleters did or did not maintain PA. Methods: One year after the cessation of Women Bound to be Active (WBA), completers (participated in posttesting; n = 30) and noncompleters (did not participate in posttesting; n = 22) responded to questionnaires and interviews assessing their body mass index …

Faculty And Staff Updates, Department Of Surgery, March 2013, Wright State University Department Of Surgery

Department of Surgery Updates

A one page newsletter created by the Department of Surgery documenting changes to the department. This issue contains a message from the chair, a list of important dates, committee meetings, scholarly activity and more.

Methyleugenol Hepatocellular Cancer Initiating Effects In Rat Liver, Gary M. Williams, Michael J. Iatropoulos, Alan M. Jeffrey, Jian-Dong Duan

NYMC Faculty Publications

Methyleugenol (MEG), a constituent of plants used in the human diet, is hepatocarcinogenic in rodents. In an experiment to elucidate its mode of action in rat liver, male F344 rats were administered MEG intragastrically at 3 doses per week for up to 16 weeks in an initiation phase, after which half the rats were fed 500 ppm phenobarbital (PB) in the diet to promote liver neoplasia and the other half were maintained on control diet for 24 weeks. At 8 and 16 week interim terminations, (32)P-nucleotide postlabeling assay revealed 3 adducts in livers of all MEG groups. The hepatocellular replicating …

Notice Of 03/01/2013 Hsc Board Of Directors Mtg, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Pharmacy Law Brief: Contemporary Legal Issues For Leadership In Non-Profits - Iv, Joseph L. Fink Iii

Pharmacy Practice and Science Faculty Publications

No abstract provided.

Physicochemical Characterization And Aerosol Dispersion Performance Of Organic Solution Advanced Spray-Dried Cyclosporine A Multifunctional Particles For Dry Powder Inhalation Aerosol Delivery, Xiao Wu, Weifen Zhang, Don Hayes Jr., Heidi M. Mansour

Pharmaceutical Sciences Faculty Publications

In this systematic and comprehensive study, inhalation powders of the polypeptide immunosuppressant drug - cyclosporine A - for lung delivery as dry powder inhalers (DPIs) were successfully designed, developed, and optimized. Several spray drying pump rates were rationally chosen. Comprehensive physicochemical characterization and imaging was carried out using scanning electron microscopy, hot-stage microscopy, differential scanning calorimetry, powder X-ray diffraction, Karl Fischer titration, laser size diffraction, and gravimetric vapor sorption. Aerosol dispersion performance was conducted using a next generation impactor with a Food and Drug Administration-approved DPI device. These DPIs displayed excellent aerosol dispersion performance with high values in emitted dose, …

Missions At Maxwell, Ashleigh Jardine

Lake Union Herald

No abstract provided.

Cell Death Pathways In Directly Irradiated Cells And Cells Exposed To Medium From Irradiated Cells, K.K. Jella, Amaya Garcia, Brendan Mcclean, Hugh Byrne, Fiona Lyng

Articles

Purpose: The aim of this study was to compare levels of apoptosis, necrosis, mitotic cell death and senescence after treatment with both direct radiation and irradiated cell conditioned medium. Materials and methods: Human keratinocytes (HaCaT cell line) were irradiated (0.005, 0.05 and 0.5 Gy) using a cobalt 60 teletherapy unit. For bystander experiments, the medium was harvested from donor HaCaT cells one hour after irradiation and transferred to recipient HaCaT cells. Clonogenic assay, apoptosis, necrosis, mitotic cell death, senescence and cell cycle analysis were measured in both directly irradiated cells and bystander cells Results: A reduction in cell survival was …

Naeglaeria Infection Of The Central Nervous System, Ct Scan Findings: A Case Series, Rohana Naqi, Muhammad Azeemuddin

Department of Radiology

The imaging findings in four cases of a rare infection of the central nervous system caused by amoebae, Naeglaeria fowleri are presented. Naeglaeria fowleri are pathogenic free-living amoebae. They cause primary amoebic meningoencephalitis (PAM), a rapidly fatal disease of the central nervous system. The computed tomography brain findings in 3 (75%) of our cases of pan amoebic meningoencephalitis showed non-specific brain oedema; 2 (66%) of these cases also had moderate hydrocephalus and among that 1 (50%) case showed an old lacunar infarction in peri-ventricular region. In the remaining 1 (25%) case the scan was normal with no evidence of oedema …

The Adipose Tissue Production Of Adiponectin Is Increased In End-Stage Renal Disease., Maria P Martinez Cantarin, Scott A Waldman, Cataldo Doria, Adam M Frank, Warren R Maley, Carlo B Ramirez, Scott W Keith, Bonita Falkner

Department of Medicine Faculty Papers

Adiponectin has antidiabetic properties, and patients with obesity, diabetes, and insulin resistance have low plasma adiponectin levels. However, although kidney disease is associated with insulin resistance, adiponectin is elevated in end-stage renal disease. Here we determine whether adipose tissue production of adiponectin is increased in renal disease in a case-control study of 36 patients with end-stage renal disease and 23 kidney donors. Blood and tissue samples were obtained at kidney transplantation and donation. The mean plasma adiponectin level was significantly increased to 15.6 mg/ml in cases compared with 8.4 mg/ml in controls. Plasma levels of the inflammatory adipokines tumor necrosis …

Agenda Of 03/01/2013 Hsc Board Of Directors Mtg, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Awareness And Beliefs Regarding Intimate Partner Violence Among First-Year Dental Students, Rhonda J. Everett, Karl Kingsley, Christina A. Demopoulos, Edward E. Herschaft, Christine Lamun, Sheniz Moonie, Timothy J. Bungum, Michelle Chino

Environmental & Global Health Faculty Research

Intimate partner violence (IPV) may affect one to four million individuals per year in the United States, with women accounting for the majority of both reported and unreported cases. Dental professionals are in a unique position to identify many types of IPV because injuries to the head and neck may be indicators or predictors of IPV abuse. Fewer than half of dental programs surveyed have reported having IPV-specific curricula, and most dental students surveyed have reported having little experience or training to recognize IPV. Based on this information, this pilot study sought to assess the awareness and beliefs regarding IPV …

Oncolog, Volume 58, Number 03, March 2013, Sarah Bronson, Zach Bohannan, Bryan Tutt

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Advances in Pulmonary Medicine Facilitate Cancer Diagnosis, Treatment: The lungs present unique challenges in cancer diagnosis and treatment-navigating a maze of bronchi to find and sample tissue that will lead to an accurate diagnosis of lung cancer, for example, or deciding whether to proceed with treatment for cancer in the presence of concomitant lung disease
• New Drugs Increase Treatment Options for Patients with Imatinib-Resistant Chronic Myeloid Leukemia: In the past year, several new targeted drugs have been approved as second-line treatments for imatinib-resistant chronic myeloid leukemia (CML). These drugs include the second-generation tyrosine kinase inhibitor bosutinib and the third-generation tyrosine …

Morphology Of Brain Waveforms And Electrical Activity Of Visual Evoked Potentials (Vep) Of Iguana Iguana Species Under Captivity Conditions In Mexico, Salvador Abraham Solís-Chávez, Alejandra Ibáñez-Contreras, Alfredo Durand-Rivera, Sergio A. Reyes-Pantoja, Alfaro Rodríguez Alfonso, Eduardo Tena-Betancourt, Braulio Hernández-Godínez

The Thai Journal of Veterinary Medicine

Reptiles have been characterized by relevant number of papers as well-known animal models in biomedical research and neuroethology due to their ancestral evolutionary relationship with birds and mammals, leading to further hypothesis that the dorsal ventricular ridge (DVR), the dorsal pallia of amphibians and the isocortex of mammalian brains share a common anatomical origin. The objective of this study was to assess the morphologic features and measurement of brain waveforms of Iguana iguana through Visual Evoked Potentials (VEP). This research employed six healthy and ophthalmologically-suited iguanas (Iguana iguana), with computerized tomography brain scans followed by VEP under simple temporary physical …

Dha Analysis In Different Types Of Egg Yolks: Its Possibility Of Being A Dha Source For Boar Semen Cryopreservation, Kampon Kaeoket, Panida Chanapiwat

The Thai Journal of Veterinary Medicine

The aim of this study was to investigate the concentrations of Docosahexaenoic acid (DHA) in DHA enriched hen egg yolk (H-DHA) in comparison with egg yolk from chicken, duck, quail, ostrich and crocodile in order to find a source of DHA for boar semen cryopreservation. A pool (10 eggs in each) of DHA enriched hen egg yolk and egg yolks from chicken, duck, quail, ostrich and crocodile were analyzed for fatty acids profile at the Nutrition Laboratory, Mahidol University. Comparing all egg yolks, the highest DHA concentration in egg yolk was found in H-DHA egg yolk (3.7% of total fatty …

Cloning Efficiency Of Canine Mesenchymal Stem Cells Isolated From Bone Marrow Of Femoral Head And Subcutaneous Adipose Tissue, Nada Tanamai, Sirirak Chantakru, Monchanok Vijarnsorn

The Thai Journal of Veterinary Medicine

Most recently, adipose tissue (AD) has become an alternative source for mesenchymal stem cells (MSCs) instead of the invasive method of bone marrow (BM) aspiration both in human and canine. In this study, we compared MSCs derived from adipose tissue (AD-MSCs) and bone marrow (BM-MSCs) regarding morphology and cell yield for instant usage by using the standard protocol of counting colony forming unit-fibroblast (CFU-F). MSCs from both sources showed fibroblast-like morphology and formed colonies termed as CFU-F after culturing in plastic surface for 10 days. The colony number per mononuclear cells (MNCs) and the colony number per adherent cells derived …

Histomorphometrical Variations Of Hair Follicles Of Bakhtiari Sheep At Different Skin Areas, Behzad Mobini

The Thai Journal of Veterinary Medicine

The purpose of this study was to determine the histomorphometrical variations of hair follicles at different skin areas in Bakhtiari sheep. Twelve healthy adult sheep (6 males and 6 females) of the Bakhtiari breed, aged from 1 to 2 years, were selected from the abattoir of Shahrekord. Skin samples were taken from different areas, fixed and stained with haematoxylin and eosin. By using lattice line graticule (5x5) and ocular micrometer, the following histomorphometric indices were tested: number of primary and secondary follicles per one mm2; depth and width of primary and secondary follicles; ratios of number, depth and width of …

Statistical Study Of The Association Between Shelter Canine Intakes And Euthanasia From 2001 To 2011 In Taiwan, I-Feng Yen, Hsiu-I Lin, Dang-Jie Lan, Ting-Wei Chang, Kai Pan, Chang-Young Fei

The Thai Journal of Veterinary Medicine

This study used Pearson correlation test to analyze statistical correlation between shelter canine intake and number of dogs euthanized in municipal animal shelters in 20 counties/cities in Taiwan from 2001 to 2011. Data of animal shelters were official data provided by the Council of Agriculture, the competent authority of the Animal Protection Act in Taiwan. Among the 20 counties/cities in Taiwan, Hualien County, Penghu County, Keelung City, and Chiayi County were excluded from this study due to incomplete data. Pearson correlation test was used to analyze the data of other 16 counties/cities from 2001 to 2011. Among these 16 counties/cities, …

Effect Of Wild Cape Gooseberry (Physalis Minima Linn.) On Zebra Fish (Danio Rerio) Embryo, Aranya Ponpornpisit, Nopadon Pirarat, Wanwipa Suthikrai, Anong Binwihok

The Thai Journal of Veterinary Medicine

The effect of crude extract of wild cape gooseberry, P. minima Linn. on zebra fish, D. rerio, embryo was investigated. Five concentrations (0.01%, 0.1%, 1%, 10% and 20%) of an aqueous crude extract of the plant leaf was prepared and tested with newly spawned embryos in 96 well plates. The observation effect was based on the toxicity endpoint composed of lethal effects, sublethal effects and malformation effects appearing within 144 hours postfertilization (hpf). The results suggested that the lowest observed effect concentrations (LOEC) for a lethal effect and a sublethal effect were 20% and 10% respectively. Not fully developed pigmentation …

Survey Of Toxoplasma Gondii In Taipei: Livestock Meats, Internal Organs, Cat And Dog Sera, Ying-Bin Taiching Fuh, Albert Taiching Liao, Yun-Ming Taiching Pong, Meng-Chih Taiching Tung, Chang-Young Taiching Fei, Dah-Sheng Lin

The Thai Journal of Veterinary Medicine

Toxoplasma gondii (T. gondii) is an important food-borne zoonotic protozoa. Infection occurs when humans and warm-blooded animals consume raw or lightly cooked cysts containing meat or sporulated oocysts contaminated food. T. gondii infection has been observed in food animals in many countries suggesting the significance of food animals in the epidemiology of toxoplasmosis. However, there is no report regarding T. gondii infection in food animals other than pigs in Taiwan. Therefore, in this study, pork, pig livers, mutton, chicken flesh, chicken hearts, chicken livers, gizzards, and imported beef sold in the supermarkets in Taipei were examined for T. gondii deoxyribonucleic …

Ecg Quiz, Chollada Buranakarl, Suwanakiet Sawangkoon, Chutamas Benjanirut, Monkon Trisiriroj, Thanusorn Phakhawambodee

The Thai Journal of Veterinary Medicine

No abstract provided.

Ophthalmology Snapshot, Nalinee Tuntivanich

The Thai Journal of Veterinary Medicine

No abstract provided.

What Is Your Diagnosis, Pranee Tuntivanich, Suwicha Chuthatep, Panida Pongvittayanon

The Thai Journal of Veterinary Medicine

No abstract provided.

Morphological Aspects By Light And Scanning Electron Microscopic Studies Of Swamp Buffalo Endometrium At Follicular And Mid-Luteal Phases, Paisan Tienthai, Kriengyot Sajjarengpong

The Thai Journal of Veterinary Medicine

This study was carried out to observe morphological changes of swamp buffalo endometrium at follicularand mid-luteal phases. Uterine horns were collected from female buffaloes at a local abattoir and the selected estrousstages were categorized into the follicular (n = 10) and mid-luteal (n = 10) phases. General histology andhistomorphometry were examined under light microscope (LM) whereas a scanning electron microscope (SEM) wasused to study surface epithelial changes. The results showed that the height of the endometrial epithelium, thenumber of superficial endometrial glands and the number of capillaries were significantly greater (p < 0.05) at thefollicular phase. By SEM examination, the ciliated and secretory cells with different patterns, i.e. abundant microvillion the apical part or secretory protrusion in various degrees, distinctly increased at the follicular phase. In themeantime, numerous secretory cells with stubby microvilli were covered throughout the endometrial surface withsecretory vesicles on endometrial glandular orifices at the mid-luteal phase in which the ciliated cells were sparselyseen. It was concluded that the swamp buffalo endometrium obviously revealed modifications during the estrouscycle for physiological events, i.e. sperm transport, early embryonic development and implantation.