Medicine and Health Sciences Commons^™

Comprehensive Management Of Presbycusis: Central And Peripheral, Kourosh Parham

Articles - Patient Care

The prevailing otolaryngologic approach to treatment of age-related hearing loss (ARHL), presbycusis, emphasizes compensation of peripheral functional deficits (i.e., hearing aids and cochlear implants). This approach does not address adequately the needs of the geriatric population, one in five of whom is expected to consist of the “old old” in the coming decades. Aging affects both the peripheral and central auditory systems, and disorders of executive function become more prevalent with advancing age. Growing evidence supports an association between age-related hearing loss and cognitive decline. Thus, to facilitate optimal functional capacity in our geriatric patients, a more comprehensive management strategy …

Racial And Ethnic Disparities In Diabetes Complications In The Northeastern United States: The Role Of Socioeconomic Status, Julie A. Wagner

UCHC Articles - Research

The role of socioeconomic status (SES) in explaining racial/ethnic disparities in diabetes remains unclear. We investigated disparities in self-reported diabetes complications, and the role of macro (e.g., income, education) and micro (e.g., ‘owning a home’ or ‘having a checking account’) SES indicators in explaining these differences. The sample included individuals with a diagnosis of diabetes (N=795) who were on average 55 years old, and 55.6% non-Hispanic White, 25.0% African American, and 19.4% Hispanic. Approximately 8% reported nephropathy, 35% reported retinopathy, and 16% reported cardiovascular disease. There were significant disparities in the rates of complications among non-Hispanic White, African American and …

The Sh2 Domain Interaction Landscape, Kazuya Machida, Christopher M. Thompson, Bruce J. Mayer

UCHC Articles - Research

Members of the SH2 domain family modulate signal transduction by binding to short peptides containing phosphorylated tyrosines. Each domain displays a distinct preference for the sequence context of the phosphorylated residue. We have developed a new high-density peptide chip technology that allows probing the affinity of most SH2 domains for a large fraction of the entire complement of tyrosine phosphopeptides in the human proteome. Using this technique we have experimentally identified thousands of putative SH2- peptide interactions for more than 70 different SH2 domains. By integrating this rich data set with orthogonal context-specific information, we have assembled an SH2 mediated …

The Cutting Edge Spring 2013, Wright State University Department Of Surgery

The Cutting Edge Newsletter

An eight page newsletter created by the Department of Surgery documenting current affairs of the department. This issue highlights the arrival of a new faculty member, an announcement for the ACS Fellowship Program, research news, and more.

Faculty And Staff Updates, Department Of Surgery, April 2013, Wright State University Department Of Surgery

Department of Surgery Updates

A four page newsletter created by the Department of Surgery documenting changes to the department. This issue contains a message from the chair, a list of important dates, committee meetings, scholarly activity and more.

Mid-Atlantic Ethics Committee Newsletter, Spring 2013

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

Guardian Engagement Learning Community 2012-2013, Ebony Allen, Paige Kulie, Risa Nakajima, Sarah Scheinfeld, Jordanna Snyder, Julia Song, Zachary Spoehr-Labutta, Kelly Worden

ISCOPES Posters and Presentations

No abstract provided.

Healthy Teen Scholars, Tanya Abraham, Katherine Boretsky, Shari Boyce, Nikita Desai, Odera Ekwunife, Rachel Glassford, Ahimsa Govender, Dolores Prudent, Anna Yakovleva

ISCOPES Posters and Presentations

No abstract provided.

Com Outlook Spring 2013, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

The Lli Chronicle Volume 4 Number 2, Nova Southeastern University

Lifelong Learning Institute Newsletters

No abstract provided.

Patient-Driven Resource Planning Of A Health Care Facility Evacuation, Bruno P. Petinaux, Kabir Yadav

Emergency Medicine Faculty Publications

Introduction: The evacuation of a health care facility is a complex undertaking, especially if done in an immediate fashion, ie, within minutes. Patient factors, such as continuous medical care needs, mobility, and comprehension, will affect the efficiency of the evacuation and translate into evacuation resource needs. Prior evacuation resource estimates are 30 years old.

Methods: Utilizing a cross-sectional survey of charge nurses of the clinical units in an urban, academic, adult trauma health care facility (HCF), the evacuation needs of hospitalized patients were assessed periodically over a two-year period.

Results: Survey data were collected on 2,050 patients. Units with patients …

Instrumental Music Ensemble At Tennessee State University: The Early Years (1912-1946), Reginald A. Mcdonald

The Journal of Tennessee State University

No abstract provided.

The Resilience Of One Tennessee State University Professor In Providing A Path To Excellence For Youths, Sean Daniels

The Journal of Tennessee State University

No abstract provided.

S.G.: Facilitator Notes, Lindsay St. Louis, Michael D'Apice, Kristen Brusky, Tyler Vunk

Student-led Mini-Grants

Video interviews of five chronic pain patients with differing conditions were completed; a man with chronic low back pain, a woman with fibromyalgia, a woman with rheumatoid arthritis, a man with musculoskeletal pain in addition to post-traumatic stress disorder, and a woman with a spinal cord injury. These interviews were used to make personal videos for each patient, which tell their story of chronic pain, and a longer 8-10 minute video that included all patients in addition to a young woman with complex regional pain syndrome (CRPS). They were also used to make interprofessional case reports of chronic pain with …

The Impact Of A Community–Wide Woodstove Changeout Intervention On Air Quality Within Two Schools, Tony Ward, Christopher P. Palmer, Kathi Hooper, Megan Ann Bergauff, Curis W. Noonan

Public and Community Health Sciences Faculty Publications

Due to temperature inversions and widespread residential woodstove use, Libby, Montana historically experienced elevated levels of ambient woodsmoke PM_2.5 throughout the winter months. In an effort to reduce wintertime PM_2.5, a large community–wide woodstove changeout was conducted between 2005 and 2007, removing nearly 1 200 old polluting stoves from service. To determine the impact of this intervention on indoor air quality, PM_2.5 sampling was conducted in the gymnasiums of an elementary and middle school before, during, and after the woodstove changeout over a four–year period. Throughout the program, results showed that indoor PM_2.5 concentrations at …

Discovery Of Molecular Associations Among Aging, Stem Cells, And Cancer Based On Gene Expression Profiling., Xiaosheng Wang

Journal Articles: Genetics, Cell Biology & Anatomy

The emergence of a huge volume of "omics" data enables a computational approach to the investigation of the biology of cancer. The cancer informatics approach is a useful supplement to the traditional experimental approach. I reviewed several reports that used a bioinformatics approach to analyze the associations among aging, stem cells, and cancer by microarray gene expression profiling. The high expression of aging- or human embryonic stem cell-related molecules in cancer suggests that certain important mechanisms are commonly underlying aging, stem cells, and cancer. These mechanisms are involved in cell cycle regulation, metabolic process, DNA damage response, apoptosis, p53 signaling …

Mri Of Neuronal Recovery After Low-Dose Methamphetamine Treatment Of Traumatic Brain Injury In Rats, Guang Liang Ding, Michael Chopp, David J. Poulsen, Lian Li, Changsheng Qu, Qingjiang Li, Siamak P. Nejad-Davarani, John S. Budaj, Hongtao Wu, Asim Mahmood, Quan Jiang

Biomedical and Pharmaceutical Sciences Faculty Publications

We assessed the effects of low dose methamphetamine treatment of traumatic brain injury (TBI) in rats by employing MRI, immunohistology, and neurological functional tests. Young male Wistar rats were subjected to TBI using the controlled cortical impact model. The treated rats (n = 10) received an intravenous (iv) bolus dose of 0.42 mg/kg of methamphetamine at eight hours after the TBI followed by continuous iv infusion for 24 hrs. The control rats (n = 10) received the same volume of saline using the same protocol. MRI scans, including T2-weighted imaging (T2WI) and diffusion tensor imaging (DTI), were performed one day …

Environmental Temperature And Exercise-Induced Blood Oxidative Stress, John C. Quindry, Lindsey Miller, Graham Mcginnis, Brian Kliszczewiscz, Dustin R. Slivka, Charles Dumke, John S. Cuddy, Brent Ruby

Integrative Physiology and Athletic Training Faculty Publications

Previous research findings indicate that environmental temperature can influence exercise-induced oxidativestress responses, although the response to variable temperatures is unknown. The purpose of this study was to investigate the effect of warm, cold, and “neutral,” or room, environmental temperatures on the blood oxidative stress associated with exercise and recovery. Participants (N = 12, age 27 ± 5 yr, VO_2max = 56.7 ± 5.8 ml · kg^–1 · min^–1, maximal cycle power output = 300 ± 39 W) completed 3 exercise sessions consisting of a 1-hr ride at 60% W_max, at 40% relative humidity …

The Alternative Appeal, Courtney Deroo

Annual Celebration of Student Scholarship and Creativity

For decades, Americans expressed dissatisfaction with conventional cancer treatments. I examine the appeal of biological alternatives to surgery, chemotherapy, and radiation therapy for patients with cancer. The limited effectiveness and side effects of many conventional cancer therapies led many patients to pursue a variety of unconventional therapies. To improve the quality of care for cancer patients, "mainstream" providers must better understand, and even collaborate with, alternative practitioners.

Diffusion Of Mobile Payment Systems Among Microentrepreneurs In Kenya And Tanzania, Dionne Nickerson

Annual Celebration of Student Scholarship and Creativity

The rapid rise of Kenya's mobile payment system, M-PESA , has grasped the attention of policy makers and private enterprise alike. In just six years M-PESA has transformed how money flows throughout Kenya, and similar systems are gaining traction elsewhere in Africa. This project examines the impact of mobile payment system adoption on the economic advancement of Kenyan and Tanzanian microentrepreneurs. This work will further the understanding of mobile payment systems’ contribution to the economic growth of microenterprises, which may have implications for poverty reduction in these two nations.

Self-Directed Learning Readiness And Self-Determination For Selected Rehabilitation Professional Students: The Impact Of Clinical Education, Shelley S. Payne, Peter Rundquist, William V. Harper, Julie Gahimer

Mathematics Faculty Scholarship

In a time of rapidly changing medical information, practitioners must have learning skills that enable them to be effective life-long learners. A part of an examination of a final clinical internship for rehabilitation professionals was a pre-post measure of learner self-direction and self-determination. Two instruments, the Self-Directed Learning Readiness Scale (SDLRS) and the Academic Motivation Scale (AMS- reported as Self-Determination Index (SDI) were used with a sample of Doctorate of Physical Therapy (DPT) and Master of Occupational Therapy (MOT) students. Pre-testing occurred just prior to and post-testing just after the subjects’ final clinical assignments. Both groups increased mean scores from …

Chironian Spring/Summer 2013, New York Medical College

The Chironian

No abstract provided.

Evaluation Of The Care Program At Goodall Hospital's Center For Women's Health, Nicole Hutzler, Lindsey M. Stockwell

Thinking Matters Symposium Archive

Sanford was designated by Maine's Governor in 2009 as a "medically underserved community." Communities with this designation have limited primary care providers, and high infant mortality and poverty rates. Goodall Hospital developed the CARE Program in response to this issue, which serves pregnant women by connecting them with a social worker designated as the CARE Coordinator (CC). This study examines the effectiveness of the program's interventions which assess and treat depression and encourage engagement in prenatal care. Primary data was collected from health records of women enrolled in the CARE Program at Goodall Hospital's Center for Women's Health. This descriptive …

Administrative Issues Journal: Table Of Contents

Administrative Issues Journal

No abstract provided.

Anti-Seizure Medications And Estradiol For Neuroprotection In Epilepsy: The 2013 Update, Libor Velisek, Nino Nebieridze, Tamar Chachua, Jana Veliskova

NYMC Faculty Publications

Current epilepsy therapy is still symptomatic using anti-seizure, rather than anti-epileptic, medications. This therapy may control the seizure activity but does not prevent or even cure epilepsy. Treatment strategies that could interfere with the process leading to epilepsy (epileptogenesis) would have significant benefits over the current approaches. Neuronal damage contributing to remodeling of the neuronal networks (such as in the hippocampus during temporal lobe epilepsy) is one of the significant components of ongoing epileptogenesis. Thus, treatment strategies alleviating seizure-induced neuronal damage and network reorganization may become powerful tools fighting the deteriorating process of epileptogenesis. Current anti-seizure medications, especially valproic acid, …

The Antibiotic Revolution, Alyssa Olsen

Spring 2013, Kuhn's Philosophy of Science

In 1928, Alexander Fleming discovered Penicillin, which revolutionized the way infections were treated. This discovery was revolutionary because it impacted the scientific field, the medical field, the pharmaceutical industry, and all of humanity. Alexander Fleming’s discovery of Penicillin sparked the development of antibiotics, which has continued to save people’s lives since the revolution. Thomas Kuhn would qualify the discovery of Penicillin by Alexander Fleming as a revolution because it led to a paradigm shift. Prior to the discovery of Penicillin, patients died from trivial injuries and infections. Fleming’s discovery of Penicillin is revolutionary because it changed the worldview of the …

Legislative Impact Of The Construction Of An “Abortion Culture”: A Comparative Analysis Of The Enaction And Impact Of Abortion Restriction Legislation In The Netherlands And The United States, Anna Schmitz

Independent Study Project (ISP) Collection

This study investigates the different socio-political causes leading to the implementation of similar abortion restrictions (mandatory parental notification for minors, mandatory counseling, and a waiting period) in the Netherlands and the United States. It first investigates the “abortion cultures” of the two countries, using personal interviews with Dutch and American citizens to analyze the social perceptions of abortion and a comparison of sexual health and legislation data to create a wider picture of abortion within both countries. It then investigates the political opportunity structure leading to the implementation of the restrictions of abortion in each country, and then investigates differences …

[Sabbatical Report], Emmanuel Iyiegbuniwe

Sabbatical Reports

The main purpose of this sabbatical leave was to provide me the opportunity to conduct relevant research and subsequently write two book chapters on environmental health and policy issues in two countries: Belize (a developing country) and Canada (a developed country). Specifically, the two book chapters were titled "Analysis of Environmental Health Policy in Belize" and "Analysis of Environmental Health and Policy Issues in Canada." As called for in my proposal, I was able to travel to Belize with a group of CHHS faculty and students during the 2013 winter term. During the leave period, I success fully conducted research …

Transport And Health: A Look At Three Latin American Cities, Janeth Mosquera Becerra, Rodrigo S. Reis, Lawrence D. Frank, Farah A. Ramirez-Marrero, Benjamin Welle, Eugenio Arriaga Cordero, Fabian Mendez Paz, Carlos J. Crespo, Veronica Dujon, Enrique Jacoby, Jennifer Dill, Lynn Weigand, Carlos M. Padin

Community Health Faculty Publications and Presentations

Transport is associated with environmental problems, economic losses, health and social inequalities. A number of European and US cities have implemented initiatives to promote multimodal modes of transport. In Latin America changes are occurring in public transport systems and a number of projects aimed at stimulating non-motorized modes of transport (walking and cycling) have already been implemented. Based on articles from peer-reviewed academic journals, this paper examines experiences in Bogota (Colombia), Curitiba (Brazil), and Santiago (Chile), and identifies how changes to the transport system contribute to encourage active transportation. Bus rapid transit, ciclovias, bike paths/lanes, and car use restriction are …

Reaching Millennium Development Goal Target 5.A.: Progress Towards Improving Maternal Health, Christina Kang

Independent Study Project (ISP) Collection

In September 2000, 189 countries agreed upon striving to reach Millennium Development Goal 5, making great strides to improving maternal health by 2015. The indicators that would prove the goal’s success were determined to be directly correlated to a reduction of three-quarters of Maternal Mortality Ratio (MMR) from 1990 figures and having Skilled Birth Attendants (SBAs) present at all births by 2015 (United Nations, n.d.-a). Research has proven that while there has been a global trend towards reaching MDG 5, there is a large discrepancy amongst different regions and countries influencing its success. Through the usage of official United Nations …