Medicine and Health Sciences Commons^™

A Study Of Coverage Optimized Planning Incorporating Models Of Geometric Uncertainties For Prostate Cancer, Huijun Xu

Theses and Dissertations

A fundamental challenge in the treatment planning process of multi-fractional external-beam radiation therapy (EBRT) is the tradeoff between tumor control and normal tissue sparing in the presence of geometric uncertainties (GUs). To accommodate GUs, the conventional way is to use an empirical planning treatment volume (PTV) margin on the treatment target. However, it is difficult to determine a near-optimal PTV margin to ensure specified target coverage with as much normal tissue protection as achievable. Coverage optimized planning (COP) avoids this problem by optimizing dose in possible virtual treatment courses with GU models directly incorporated. A near-optimal dosimetric margin generated by …

The Santa Clara, 2013-04-11, Santa Clara University

The Santa Clara

No abstract provided.

Editors’ Pick—Book Review: Intellectual Leadership In Higher Education: Renewing The Role Of The University Professor, Frederic W. Murray

Administrative Issues Journal

Macfarlane, B. 2012. Intellectual leadership in higher education: Renewing the role of the university professor. New York: Routledge 160 pp. ISBN 978-0-415-56081-8

Sweetened Drink And Snacking Cues In Adolescents. A Study Using Ecological Momentary Assessment, Jerry L. Grenard, Alan W. Stacy, Saul Shiffman, Amanda N. Baraldi, David P. Mackinnon, Ginger Lockhart, Yasemin Kisbu-Sakarya, Sarah Boyle Abd, Yuliyana Beleva Abd, Carol Koprowski, Susan L. Ames, Kim D. Reynolds

CGU Faculty Publications and Research

The objective of this study was to identify physical, social, and intrapersonal cues that were associated with the consumption of sweetened beverages and sweet and salty snacks among adolescents from lower SES neighborhoods. Students were recruited from high schools with a minimum level of 25% free or reduced cost lunches. Using ecological momentary assessment, participants (N=158) were trained to answer brief questionnaires on handheld PDA devices: (a) each time they ate or drank, (b) when prompted randomly, and (c) once each evening. Data were collected over 7days for each participant. Participants reported their location (e.g., school grounds, home), mood, social …

Food Label Literacy And Healthy Food And Exercise Promotion Among Pacific Islander Caregivers, Dr. Jane Lassetter

Journal of Undergraduate Research

Originally, I planned to collect the data in Tonga and Utah. The Tongan Ministry of Health never replied to the proposal I submitted for their review. Therefore, spring and summer 2011, I modified the study, and students and I collected data from 364 Native Hawaiian and Pacific Islander (NHPI) participants in two islands of Hawaii at a preschool and grocery stores and in Utah at NHPI events. Our research questions were the following:

Mentoring Student Research Teams In Providing Appropriate Interventions For Families Raising Children/Adolescents With Diabetes, Dr. Donna Freeborn

Journal of Undergraduate Research

This intervention project consisted of four workshops for children/adolescents with type 1 diabetes held over a four month period in Winter/Spring 2011 and then another series of workshops for children/adolescents with type 1 diabetes (T1DM), parents of these children, and siblings held over four months in Fall 2011. Evaluations and feedback from participants have been positive and underscore the need to continue these workshops on an ongoing basis. Parental workshops were conducted by Christina Yazzie, a graduate student, who presented a poster on the intervention at the Western Institute of Nursing Conference in April, 2012. Workshops for the children with …

Comparison Study Of Airway Reactivity Outcomes Due To A Pharmacologic Challenge Test: Impulse Oscillometry Versus Least Mean Squared Analysis Techniques., Elena Rodriguez, Charrell M Bullard, Milena H Armani, Thomas L Miller, Thomas H Shaffer

Department of Medicine Faculty Papers

The technique of measuring transpulmonary pressure and respiratory airflow with manometry and pneumotachography using the least mean squared analysis (LMS) has been used broadly in both preclinical and clinical settings for the evaluation of neonatal respiratory function during tidal volume breathing for lung tissue and airway frictional mechanical properties measurements. Whereas the technique of measuring respiratory function using the impulse oscillation technique (IOS) involves the assessment of the relationship between pressure and flow using an impulse signal with a range of frequencies, requires less cooperation and provides more information on total respiratory system resistance (chest wall, lung tissue, and airways). …

Quickening The Pace Towards A Huntington’S Disease Gene-Silencing Clinical Trials: Pharma Giant Roche, Isis Enter Partnership, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Caveolar Fatty Acids And Acylation Of Caveolin-1, Qian Cai, Ling Guo, Haiqing Gao, Xiang-An Li

Pediatrics Faculty Publications

PURPOSE: Caveolae are cholesterol and sphingolipids rich subcellular domains on plasma membrane. Caveolae contain a variety of signaling proteins which provide platforms for signaling transduction. In addition to enriched with cholesterol and sphingolipids, caveolae also contain a variety of fatty acids. It has been well-established that acylation of protein plays a pivotal role in subcellular location including targeting to caveolae. However, the fatty acid compositions of caveolae and the type of acylation of caveolar proteins remain largely unknown. In this study, we investigated the fatty acids in caveolae and caveolin-1 bound fatty acids.

METHODS: Caveolae were isolated from Chinese hamster …

Rural School Employees' Awareness And Perceptions Of Adult Vaccinations: A District-Wide Study, Eli Gary Thornton

Theses and Dissertations

As key members of the school environment, it is important for school employees to be vaccinated. Employees are in direct contact with children in close quarters for long periods of time and such an environment can easily serve as an outbreak center for vaccine-preventable communicable diseases such as measles. Despite the fact that most school employees believe vaccines are safe and effective and many school employees report they are up-to-date with their vaccines, a closer examination reveals discrepancy between belief and behavior. As a vaccine advocate, the school nurse can be influential in providing adult vaccination education for school employees, …

A Systematic Review Of Ptsd Prevalence And Trajectories In Dsm-5 Defined Trauma Exposed Populations: Intentional And Non-Intentional Traumatic Events, Patcho N. Santiago, Robert J. Ursano, Christine L. Gray, Robert S. Pynoos, David Spiegel, Roberto Lewis-Fernandez, Matthew Friedman, Carol S. Fullerton

Dartmouth Scholarship

Objective: We conducted a systematic review of the literature to explore the longitudinal course of PTSD in DSM-5-defined trauma exposed populations to identify the course of illness and recovery for individuals and populations experiencing PTSD.

Methods: We reviewed the published literature from January 1, 1998 to December 31, 2010 for longitudinal studies of directly exposed trauma populations in order to: (1) review rates of PTSD in the first year after a traumatic event; (2) examine potential types of proposed DSM-5 direct trauma exposure (intentional and non-intentional); and (3) identify the clinical course of PTSD (early onset, later onset, chronicity, remission, …

Parasitological Prevalence Of Bovine Trypanosomosis In Kubo Division Of Kwale County Of Coastal: Baseline Survey, N. Mbahin, H. Affognon, J. Andoke, M. Tiberius, D. Mbuvi, J. Otieno, P. Muasa, R. K. Saini

All Peer-Reviewed Publications

Prior to field trials of large scale tsetse repellent technology validation in July 2011, a cross-sectional survey of bovine trypanosomosis and its vectors was carried out to know the disease level in Kwale County of Coastal Kenya. A total of 584 adult cattle were examined at ten different Locations. The trypanosome prevalence in cattle with regard to age, sex, location and apparent tsetse density was investigated. The overall trypanosome prevalence in cattle in Kubo Division of Kwale County was 33.9%. Two types of infections were recorded in various parts of the Division in the following proportions: T. congolense 61.1%, T. …

Conference Learnings, Sarah Scholl Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Query Theory - Knowing What We Want By Arguing With Ourselves, Elke Weber

Psychology Colloquia

Psychologists and behavioral economists agree that many of our preferences are constructed, rather than innate or pre-computed and stored. Little research, however, has explored the implications that established facts about human attention and memory have when people marshal evidence for their decisions. This talk provides an introduction to Query Theory, a psychological process model of preference construction that explains a broad range of phenomena in individual choice with important personal and social consequences, including our reluctance to change and excessive impatience when asked to delay consumption.

Tolerance As Civility In Contemporary Workplace Diversity Initiatives, C. W. Von Bergen, George Collier

Administrative Issues Journal

Valuing diversity emphasizes the awareness, recognition, understanding, and appreciation of human differences and revolves around creating an inclusive environment in which everyone feels esteemed. This generally takes place through a series of management education and training programs that attempt to improve interpersonal relationships among workers by asking participants to become more tolerant—generally understood today as an approval and acceptance of others’ practices, opinions, and beliefs. Because tolerance is such a highly desirable quality in U.S. society, and seemingly one of its few non-controversial values, rarely is its significance questioned. Nevertheless, contemporary interpretations of tolerance may be problematic for multicultural programs. …

Tamziq, Scattered And Connected: A Conversation In Art By Middle Eastern And American Artists, Paul Atwood, William Joiner Center For The Study Of War And Social Consequences, University Of Massachusetts Boston

Office of Community Partnerships Posters

The number of Iraqi refugees resettled in the United States has grown from only 202 in 2006 to approximately 17,000 in 2009. Since 2007, 58,810 Iraqi refugees have arrived in the United States. This group now forms the largest refugee population in the state of Massachusetts. At the same time, a large number of veterans are returning from Iraq and Afghanistan.

This project recognizes the increasing need for dialogue and exchange with and within these communities and a further need to broaden understanding of the cultural influences on our changing communities.

Gokids Boston Youth Fitness, Training, And Research Center, Gokids Boston, University Of Massachusetts Boston

Office of Community Partnerships Posters

GoKids Boston embodies innovation and leadership in youth health through life-changing programs, groundbreaking research, exceptional training opportunities, and dedication to the community with a focus on eliminating health disparities.

Local Health Departments’ Plan To Seek Voluntary National Accreditation And Its Association With Phab Accreditation Prerequisites, Gulzar H. Shah, Kate Beatty, Carolyn Leep

Health Policy & Management: Faculty Presentations (2008-2022)

Research Objective: To examine the nature of relationship between LHDs’ intentions to seek Public Health Accreditation Board (PHAB) accreditation in the future and having completed within five years the three PHAB pre-requisites: community health assessment (CHA), community health improvement plan (CHIP), and the agency-wide strategic plan.

Data Sets And Sources: We used data from the NACCHO’s 2010 National Profile of Local Health Departments (2010 Profile Study) survey, administered to 2,656 LHDs, with a module sent to a nationally representative stratified random sample of 625 LHDs which contained questions on LHDs’ plans to seek voluntary national accreditation (the dependent …

Treatment Of Intractable Neurogenic Cough With Cricopharyngeal Myotomy, Anne Lee Durstenfeld, Bs, Joseph Spiegel, Md, Mauritis Boon, Md

Department of Otolaryngology - Head and Neck Surgery Presentations and Grand Rounds

Objectives: Neuropathic cough that is incompletely responsive to medical therapy may be due to cricopharyngeal hypertonicity. The objective was to describe the utility of cricopharyngeal myotomy in alleviating symptoms of intractable neuropathic cough.

Study Design: Retrospective review.

Methods: A retrospective chart review was performed for three patients who underwent cricopharyngeal myotomy for intractable cough. Trigger phenomena, previous evaluation and treatment, and outcomes after surgery, namely patient perception of improvement and medication use after surgery, were assessed and documented.

Results: After cricopharyngeal myotomy, all three patients noted symptomatic improvement and were weaned off medication. Continued improvement was noted at follow …

Clarifying And Expanding Concepts Of Cross-Jurisdictional Sharing: Early Lessons Learned From Conducting Qi With Georgia’S Health Districts, William C. Livingood, Nandi A. Marshall, Angela Peden, Ketty Gonzales, Gulzar H. Shah, Dayna S. Alexander, Alesha Wright, Russell B. Toal, Lynn S. Woodhouse, Deanna Keene

Health Policy & Management: Faculty Presentations (2008-2022)

Research Objective: Assess the legal and organization cultural foundations for Cross-Jurisdictional Sharing (CJS) in support of local public health accreditation and QI in Georgia.

Data Sets and Sources: Archival data (primarily state statutes), secondary data from previous qualitative comparative research on Deep South public health organization, secondary data from previous surveys, and oral interviews and written communication.

Study Design: Primarily Qualitative design combining ethnographic and participatory research methods.

Analysis: Qualitative Content analysis based on predetermined and emergent themes.

Principal Findings: Georgia’s Health Districts have emerged as major CJS entities that support delivery of essential services and local public health (LPH) …

Predictors Of Evidence-Based Decision Making And Population Health Practice In Lhds, Kay Lovelace, Robert Aronson, Kelly Rulison, Gulzar H. Shah, Mark Smith

Health Policy & Management: Faculty Presentations (2008-2022)

Research Objective: To identify the frequency with which LHDs carry out Evidence-Based Decision Making (EBDM) and population health strategies in LHDs and state-, LHD-, and community-levels predictors of LHDs' use of these strategies.

Data Sets and Sources: Harmonized PHSSR dataset consisting of 2010 NACCHO Profile of Local Health Departments Survey, Module 2 respondents, 2010 ASTHO Profile of State Health Departments, US Census data, and Area Resource File data.

Study Design: The study used multivariate analysis to identify predictors of EBDM and population health. We identified items in the 2010 NACCHO Profile Survey representing EBDM and population health strategies and …

There Is No “I” In Team: Players, Leaders, And Team Performance In Public Health Emergency Response, William Riley, Paige Anderson Bowen, Micky Scullard, Cheryl Petersen-Kroeber, Gulzar H. Shah

Health Policy & Management: Faculty Presentations (2008-2022)

Research Objective: Research objectives are to: 1) assess effect of controller-led in situ simulation on emergency response capacity of state health department; 2) study effects of training on team function, dynamics, and communications among staff responsible for emergency operations at state health department; and 3) train public health teams for high reliability.

Data Sets and Sources: Thirty trials (one-hour functional exercises) conducted in the state department operations center over a 16-month period (May 2010 to September 2011). Data gathered using in situ simulation methodology (recording, live viewing, playback analysis). Behavioral markers data collected using event set observational tool …

A Review Of Nutritional Factors In Hypertension Management., Ha Nguyen, Olaide A Odelola, Janani Rangaswami, Aman Amanullah

Department of Medicine Faculty Papers

Hypertension is a major health problem worldwide. Its attendant morbidity and mortality complications have a great impact on patient's quality of life and survival. Optimizing blood pressure control has been shown to improve overall health outcomes. In addition to pharmacological therapies, nonpharmacological approach such as dietary modification plays an important role in controlling blood pressure. Many dietary components such as sodium, potassium, calcium, and magnesium have been studied substantially in the past decades. While some of these nutrients have clear evidence for their recommendation, some remain controversial and are still of ongoing study. Dietary modification is often discussed with patients …

Community Built Environment And Multilevel Social Determinants Of Obesity: Evidence From China Health And Nutrition Survey, Libin Zhang, Tim F. Liao, Laura L. Hayman

Office of Community Partnerships Posters

The prevalence of overweight and obesity is highest in wealthy countries like the United States, but is rapidly increasing in less developed countries. From 1992 to 2002, China had an increase from 14.6% to 21.8% in overweight and obesity. Social determinants of obesity in developing countries remain poorly understood. Further, these associations may vary by community built environment (BE) of developing countries.

Awareness, Treatment And Control Of Hypertension In Kenya, Jacob Kariuki, Eileen M. Stuart-Shor, Samuel Kimani, James Muchira, Jessica Demita, Heather Milton, Mercy Kamau, Vincent Mutuma, Darren Golden, Peris Kariuki

Office of Community Partnerships Posters

The emerging epidemic of hypertension (HTN) in sub-Saharan Africa is predicted to worsen. Uncontrolled HTN is associated with CVD, high morbidity and premature mortality; hence early detection, treatment and control of HTN is critical to reduction of the associated sequelae. The study was guided by the Social Ecological Model and principles of Community Based Participatory Research.

Mirebalais, Haiti Planning Initiative, Jack Wiggin, Urban Harbors Institute, University Of Massachusetts Boston

Office of Community Partnerships Posters

The Mirebalais Planning Initiative (MPI), a joint project of the Urban Harbors Institute at UMass Boston, Boston University, and the University of the West Indies, is funded by the W.K. Kellogg Foundation. The initiative is a community-based participatory planning process designed to expand community leadership and decision-making capacity among community members in Mirebalais, Haiti.

Healthy Aging In Massachusetts: Reporting Indicators, Identifying Resources & Activating Allies, Elizabeth Dugan, Frank Porell, Nina Silverstein, Ruth Palombo, Chae Man Lee, Kristina Turk

Office of Community Partnerships Posters

In Massachusetts, a Healthy Aging Collaborative comprised of a diverse group of stakeholders has been formed for multiple purposes: information sharing around healthy aging, idea generation, partnership building and activity mapping.

Leadership Education In Neurodevelopmental Disabilities (Lend) - Partnership With Community-Based Organizations (Cbos), Institute For Community Inclusion, University Of Massachusetts Boston

Office of Community Partnerships Posters

Interdisciplinary Leadership Education in Neurodevelopmental Disabilities (LEND), a Maternal and Child Bureau (MCHB)-funded program providing long-term, graduate level training to health professionals and family members.

The Gastón Institute’S Partnership With The Puerto Rican Cultural Center In Springfield, Ma, Gaston Institute, University Of Massachusetts Boston

Office of Community Partnerships Posters

No abstract provided.

Cruza: The Alliance For Latino Health Through Faith And Action, A Umass Boston - Dana-Farber/Harvard Cancer Center Partnership For Community-Based Research, Gaston Institute, University Of Massachusetts Boston, Dana-Farber/Harvard Cancer Center

Office of Community Partnerships Posters

CRUZA is a community-based participatory research partnership aimed at shifting the focus from intervention delivery on an individual level to a focus on enhancing the capacity of community organizations. CRUZA intends to activate collective resources to translate scientific evidence into strategies that increase cancer screening among Latinos in Massachusetts.