Medicine and Health Sciences Commons^™

Significant Sequelae After Bacterial Meningitis In Niger: A Cohort Study, Jean-François Jusot, Zilahatou Tohon, Abdoul Aziz Yazi, Jean-Marc Collard

Epidemiology and Environmental Health Faculty Publications

BACKGROUND: Beside high mortality, acute bacterial meningitis may lead to a high frequency of neuropsychological sequelae. The Sahelian countries belonging to the meningitis belt experience approximately 50% of the meningitis cases occurring in the world. Studies in Africa have shown that N. meningitidis could cause hearing loss in up to 30% of the cases, exceeding sometimes measles. The situation is similar in Niger which experiences yearly meningitis epidemics and where rehabilitation wards are rare and hearing aids remain unaffordable. The aim of this study was to estimate the frequency of neuropsychological sequelae after acute bacterial meningitis in four of the …

Genome Analysis Of Staphylococcus Aureus St291, A Double Locus Variant Of St398, Reveals A Distinct Genetic Lineage, Marc Stegger, Maliha Aziz, Tomsz Chroboczek, Lance B. Price, Troels Ronco, Kristoffer Kiil, Robert L. Skov, Frederic Laurent, Paal S. Andersen

Environmental and Occupational Health Faculty Publications

Staphylococcus aureus ST291 has been reported as a homologue recombinant double locus variant of the livestock associated S. aureus ST398. However, whole genome sequencing show that ST291 is a unique genetic lineage with highly variable content within its accessory genome compared to both human and livestock associated genome sequenced CC398s.

2013 May 21 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Expanding Access To Malaria Diagnosis Through Retail Shops In Western Kenya: What Do Shop Workers Think?, Andria Rusk, Catherine Goodman, Violet Naanyu, Beatrice Koech, Andrew Obala, Wendy Prudhomme O'Meara

Collected Faculty Scholarship

Background. The common symptoms of malaria reduce the specificity of clinical diagnosis. Presumptive treatment is conventional but can lead to overdiagnosis of malaria, delay of appropriate treatment, overprescription of antimalarials, and drug resistance. Routine use of diagnostic tests can address many of these concerns. Though treatment is often procured from retailers, there is low availability of rapid diagnostic tests for malaria (MRDTs), a simple, inexpensive, and accurate diagnostic solution. We know little about the challenges to expanding access to diagnostics through these outlets. Methods. To understand the perceptions of the benefits and challenges to selling rapid diagnostic tests for malaria, …

Measurement Of Clinical Risk Of Stigma And Discrimination Of Mental Illnesses, Amresh Srivastava, Yves Bureau, Nitika Rewari, Megan Johnston, Arman Panday, Nilesh Shah

Data and Test Instruments

Abstract Background: Stigma and discrimination continue to be a reality in the lives of people suffering from mental illness, particularly schizophrenia, and prove to be some of the greatest barriers to access care, continue to remain under care, and regain a normal lifestyle and health. Research advances have defined stigma, assessed its implications and have even examined intervention strategies for dealing with stigma. The delay in treatment due to stigma causes potential complications like suicide, violence, harm to others and deterioration in capacity to look after one’s physical health. These are preventable clinical complications. In order to deal with the …

National Estimates Of Emergency Department Visits For Pediatric Severe Sepsis In The United States, Sara Singhal, Mathias W. Allen, John-Ryan Mcannally, Kenneth S. Smith, John P. Donnelly, Henry E. Wang

Emergency Medicine Faculty Publications

Objective. We sought to determine the characteristics of children presenting to United States (US) Emergency Departments (ED) with severe sepsis.

Study design. Cross-sectional analysis using data from the National Hospital Ambulatory Medical Care Survey (NHAMCS). Using triage vital signs and ED diagnoses (defined by the International Classification of Diseases, Ninth Revision codes), we identified children(triage fever or ICD-9 infection) and organ dysfunction (triage hypotension or ICD-9 organ dysfunction).

Results. Of 28.2 million pediatric patients presenting to US EDs each year, severe sepsis was present in 95,055 (0.34%; 95% CI: 0.29-0.39%). Fever and respiratory infection were the most common indicators of …

Human Prostatic Acid Phosphatase: Structure, Function And Regulation., Sakthivel Muniyan, Nagendra K. Chaturvedi, Jennifer G. Dwyer, Chad A. Lagrange, William G. Chaney, Ming-Fong Lin

Journal Articles: Biochemistry & Molecular Biology

Human prostatic acid phosphatase (PAcP) is a 100 kDa glycoprotein composed of two subunits. Recent advances demonstrate that cellular PAcP (cPAcP) functions as a protein tyrosine phosphatase by dephosphorylating ErbB-2/Neu/HER-2 at the phosphotyrosine residues in prostate cancer (PCa) cells, which results in reduced tumorigenicity. Further, the interaction of cPAcP and ErbB-2 regulates androgen sensitivity of PCa cells. Knockdown of cPAcP expression allows androgen-sensitive PCa cells to develop the castration-resistant phenotype, where cells proliferate under an androgen-reduced condition. Thus, cPAcP has a significant influence on PCa cell growth. Interestingly, promoter analysis suggests that PAcP expression can be regulated by NF-κB, via …

What's Happening: May 20, 2013, Maine Medical Center

What's Happening

No abstract provided.

Ada News - 05/20/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Effects Of Patient-Directed Music Intervention On Anxiety And Sedative Exposure In Critically Ill Patients Receiving Mechanical Ventilatory Support: A Randomized Clinical Trial, Jill L. Guttormson, Linda L. Chlan, Craig R. Weinert, Annie Heiderscheidt, Mary Fran Tracy, Debra J. Skaar, Kay Savik

College of Nursing Faculty Research and Publications

Importance: Alternatives to sedative medications, such as music, may alleviate the anxiety associated with ventilatory support.

Objective: To test whether listening to self-initiated patient-directed music (PDM) can reduce anxiety and sedative exposure during ventilatory support in critically ill patients.

Design, Setting, and Patients: Randomized clinical trial that enrolled 373 patients from 12 intensive care units (ICUs) at 5 hospitals in the Minneapolis-St Paul, Minnesota, area receiving acute mechanical ventilatory support for respiratory failure between September 2006 and March 2011. Of the patients included in the study, 86% were white, 52% were female, and the mean (SD) age was …

Conference Learnings, Pamela Swoyer Bsn, Rn, Ccrn

Patient Care Services / Nursing

No abstract provided.

A Theoretical Comparison Of Dance/Movement Therapy And Expressive Arts Therapy, Heidi Landgraf

Creative Arts Therapies Theses

This theoretical comparison of dance/movement therapy (DMT) and expressive arts therapy (EXA) was created in order to better understand the major principles and concepts behind each field. A brief history of the predecessors of each field was discussed, along with five principles from DMT and five concepts from EXA, as chosen by the writer and based on her preferences in alignment with her personal theory and methodology. The comparison that follows discussed the ways in which both fields converge, diverge, and complement one another. The fields have many points of agreement where there is only subtle difference in language, but …

Conference Learnings, Denise Bodish Bsn, Rnbc

Patient Care Services / Nursing

No abstract provided.

Conference Learnings, Sarah Gerken Bsn, Rn

Patient Care Services / Nursing

No abstract provided.

Conference Learnings, Jane Halpin Rnc, Pcc

Patient Care Services / Nursing

No abstract provided.

Conference Learnings, Nicole J. Urban-Miller Rn, Bsn

Patient Care Services / Nursing

No abstract provided.

Bronchoscopy-Derived Correlates Of Lung Injury Following Inhalational Injuries: A Prospective Observational Study, S. W. Jones, H. Zhou, S. M. Ortiz-Puiols, R. Maile, M. Herbst, B. L. Joyner, H. Zhang, M. J. Kesic, I. Jaspers, K. A. Short, A. A. Meyer, D. B. Peden, B. A. Cairns, T. L. Noah

Physician Assistant Program

No abstract provided.

When Pictures Waste A Thousand Words: Analysis Of The 2009 H1n1 Pandemic On Television News, Westerly Luth, Cindy Jardine, Tania M. Bubela

Office of the Provost

Objectives: Effective communication by public health agencies during a pandemic promotes the adoption of recommended health behaviours. However, more information is not always the solution. Rather, attention must be paid to how information is communicated. Our study examines the television news, which combines video and audio content. We analyse (1) the content of television news about the H1N1 pandemic and vaccination campaign in Alberta, Canada; (2) the extent to which television news content conveyed key public health agency messages; (3) the extent of discrepancies in audio versus visual content.
Methods: We searched for "swine flu" and "H1N1" in local English …

The Objectives, Design And Implementation Of The Intergrowth-21st Project, Villar J, Altman D. G, Purwar M, Noble J. A, Knight H. E, Ruyan P, Ismail L. Cheikh, Barros F. C, Lambert A, Papageorghiou A. T, Maria Carvalho, Jaffer Y. A, Bertino E, Gravett M. G, Bhutta Z. A, Kennedy S. H

Obstetrics and Gynaecology, East Africa

INTERGROWTH-21st is a multicentre, multiethnic, populationbased project, being conducted in eight geographical areas (Brazil, China, India, Italy, Kenya, Oman, UK and USA), with technical support from four global specialised units, to study growth, health and nutrition from early pregnancy to infancy. It aims to produce prescriptive growth standards, which conceptually extend the World Health Organization (WHO) Multicentre Growth Reference Study (MGRS) to cover fetal and newborn life. The new international standards will describe: (1) fetal growth assessed by clinical and ultrasound measures; (2) postnatal growth of term and preterm infants up to 2 years of age; and (3) the relationship …

The Role Of Indoleamine 2,3-Dioxygenase In Lp-Bpm5 Murine Retroviral Disease Progression, Megan A. O'Connor, William R. Green

Dartmouth Scholarship

Indoleamine 2,3-dioxygenase (IDO) is an immunomodulatory intracellular enzyme involved in tryptophan degradation. IDO is induced during cancer and microbial infections by cytokines, ligation of co-stimulatory molecules and/or activation of pattern recognition receptors, ultimately leading to modulation of the immune response. LP-BM5 murine retroviral infection induces murine AIDS (MAIDS), which is characterized by profound and broad immunosuppression of T- and B-cell responses. Our lab has previously described multiple mechanisms regulating the development of immunodeficiency of LP-BM5-induced disease, including Programmed Death 1 (PD-1), IL-10, and T-regulatory (Treg) cells. Immunosuppressive roles of IDO have been demonstrated in other retroviral models, suggesting a possible …

The Lived Experiences Of African American Women With Breast Cancer: Implications For Counselors, Latasha K. Clay

LSU New Orleans Theses and Dissertations

Qualitative phenomenological methodology was used to explore the lived experiences of African American women diagnosed with breast cancer. Phenomenology focuses on the meaning of the lived experiences of individuals experiencing a concept, structure, or phenomenon (Creswell, 2007). The purpose of phenomenological research is to identify phenomena as perceived by the individual. Utilizing an existential perspective, the focus of this study was to uncover meaning which defined the essence of the participants’ experiences. Seven African American women diagnosed with breast cancer participated in this study. The participants’ ages ranged from 33-63 years. A semi-structured interview process with open-ended questions was utilized …

Research Brief: "Evaluation Of A Family-Centered Prevention Intervention For Military Children And Families Facing Wartime Deployment", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

The purpose of this study was to explore the benefits of the Families Over Coming Under Stress (FOCUS) project for families experiencing deployment. These benefits included education and skills training, with an emphasis on minimizing psychological and emotional distress for the service-people, their spouses, and their children. While this study analyzed families who were a part of the FOCUS group, future research would best serve to include an additional control group, which would allow for comparison between families in FOCUS and families not currently enrolled.

The Santa Clara, 2013-05-16, Santa Clara University

The Santa Clara

No abstract provided.

A Comparison Of Medication Managemnt Between Older And Younger Adults Living With Hiv, Judy A. Frain

Dissertations

The aims of this study were to examine whether there are differences in medication management between older and younger adults living with Human Immunodeficiency Virus and to explore the relationship between age and personal factors including cognitive ability, depression and self-efficacy on medication management. The research utilized a descriptive-correlational, cross-sectional design to compare medication management between older and younger adults living with HIV and to describe differences in predictive factors of cognition, depression, and self-efficacy on medication management ability between older and younger adults living with HIV. Results indicate both older and younger adults have high rates of mild cognitive …

The Impact Of Interventions To Reduce Length Of Stay In The Emergency Department: A Systematic Review, Jameel Abualenain, Taibah Alabdrabalnabi, Irit R. Rasooly, Paul Levett, Jesse M. Pines

Himmelfarb Library Faculty Posters and Presentations

No abstract provided.

Pilot Comparative Effectiveness Study Of Surface Perturbation Treadmill Training To Prevent Falls In Older Adults, Jon D. Lurie, Alexandra B. Zagaria, Dawna M. Pidgeon, Judith L. Forman, Kevin Spratt

Dartmouth Scholarship

Falls are the leading cause of fatal and non-fatal injuries among older adults. Exercise programs appear to reduce fall risk, but the optimal type, frequency, and duration of exercise is unknown. External perturbations such as tripping and slipping are a major contributor to falls, and task-specific perturbation training to enhance dynamic stability has emerged as a promising approach to modifying fall risk. The purpose of this pilot study was 1) to determine the feasibility of conducting a large pragmatic randomized trial comparing a multidimensional exercise program inclusive of the surface perturbation treadmill training (SPTT) to multidimensional exercise alone (Standard PT); …

Audiology Services At Remote Area Medical Expeditions In Southern Appalachia, Marc A. Fagelson

ETSU Faculty Works

This presentation summarizes the preparation for, and execution of, audiology series provided by East Tennessee State University's Audiology, Program at Remote Area Medical (RAM) expeditiors in the Southern Appalachian region. In 2010 and 2012, ETSU audiology faculty and students evaluatd 281 patients and subsequently fit 178 hearing aids.

Screening For Diabetes And Hypertension In A Rural Low Income Setting In Western Kenya Utilizing Home-Based And Community-Based Strategies, Sonak Pastakia, Shamim M. Ali, Jemima H. Kamano, Constantine O. Akwanalo, Samson K. Ndege, Victor L. Buckwalter, Rajesh Vedanthan, Gerald S. Bloomfield

Department of Pharmacy Practice Faculty Publications

BACKGROUND:

The burdens of hypertension and diabetes are increasing in low- and middle-income countries (LMICs). It is important to identify patients with these conditions early in the disease process. The goal of this study, therefore, is to compare community- versus home-based screening for hypertension and diabetes in Kenya.

METHODS:

This was a feasibility study conducted by the Academic Model Providing Access to Healthcare (AMPATH) program in Webuye, a town in western Kenya. Home-based (door-to-door) screening occurred in March 2010 and community-based screening in November 2011. HIV counselors were trained to screen for diabetes and hypertension in the home-based screening with …

Louisiana State University Health Sciences Center - 2013 - 139th Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 139th Commencement of LSU Health Sciences Center - New Orleans held May 16, 2013.

Memories Of Genetic Testing: From My Mom To Angelina Jolie, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.