Medicine and Health Sciences Commons^™

What's Happening: May 27, 2013, Maine Medical Center

What's Happening

No abstract provided.

Database-Guided Discovery Of Potent Peptides To Combat Hiv-1 Or Superbugs., Guangshun Wang

Journal Articles: Pathology and Microbiology

Antimicrobial peptides (AMPs), small host defense proteins, are indispensable for the protection of multicellular organisms such as plants and animals from infection. The number of AMPs discovered per year increased steadily since the 1980s. Over 2,000 natural AMPs from bacteria, protozoa, fungi, plants, and animals have been registered into the antimicrobial peptide database (APD). The majority of these AMPs (>86%) possess 11-50 amino acids with a net charge from 0 to +7 and hydrophobic percentages between 31-70%. This article summarizes peptide discovery on the basis of the APD. The major methods are the linguistic model, database screening, de novo …

Individual Articulator's Contribution To Phoneme Production, Jun Wang, Jordan R. Green, Ashok Samal

School of Computing: Conference and Workshop Papers

Speech sounds are the result of coordinated movements of individual articulators. Understanding each articulator’s role in speech is fundamental not only for understanding how speech is produced, but also for optimizing speech assessments and treatments. In this paper, we studied the individual contributions of six articulators, tongue tip, tongue blade, tongue body front, tongue body back, upper lip, and lower lip to phoneme classification. A total of 3,838 vowel and consonant production samples were collected from eleven native English speakers. The results of speech movement classification using a support vector machine indicated that the tongue encoded significantly more information than …

Model Kuantitatif Manajemen Kelelahan Dan Beban Kerja Untuk Peningkatan Produktivitas Pekerja Penggilingan Padi, Nur Ulfah, Panuwun Joko Nurcahyo, Irfan Dwiandhono

Kesmas

Sumber daya manusia merupakan aset penting bagi perusahaan dalam rangka peningkatan produk yang dihasilkan, salah satunya adalah sumber daya pekerja. Pekerja dengan beban kerja yang berat akan mengakibatkan terjadinya kelelahan yang pada akhirnya dapat menurunkan kualitas produk yang dihasilkan. Tujuan penelitian ini adalah mengembangkan model kuantitatif manajemen kelelahan dan beban kerja untuk meningkatkan produktivitas. Adapun metode penelitian yang digunakan adalah survei eksplanatori dengan pendekatan cross sectional dengan sampel sebanyak 45 pekerja penggilingan padi. Hasil analisis menunjukkan bahwa variabel kelelahan kerja maupun beban kerja mempunyai hubungan yang signifikan dengan produktivitas kerja. Model persamaan regresi yang terbentuk adalah produktivitas kerja = -4,188 …

Analisis Implementasi Sistem Tanggap Darurat Berdasarkan Asosiasi Perlindungan Kebakaran Nasional 1600, Meilissa Ayu Pratiwi, Fatma Lestari, Ridwansyah Ridwansyah

Kesmas

Penelitian kesesuaian pelaksanaan sistem tanggap darurat di PT X menjadi upaya untuk mempersiapkan proses tanggap darurat. Penelitian kualitatif dengan desain studi deskriptif analitik ini menggunakan dua jenis data meliputi data primer yang didapatkan melalui wawancara dan observasi, serta data sekunder melalui telaah dokumen. Tujuan penelitian ini adalah mengetahui kesesuaian implementasi sistem tanggap darurat di PT X Perusahaan Pelayanan Gas dan Minyak, ditinjau dari National Fire Protection Association 1600 (NFPA 1600) tahun 2012. Pada penelitian ini didapatkan kesesuaian implementasi sistem tanggap darurat PT X berdasarkan NFPA 1600 adalah 36,23%, sedangkan ketidaksesuainya adalah 37,60%. Diharapkan dapat mempertimbangkan saran yang diberikan untuk meningkatkan …

Gender Dan Penyakit Tuberkulosis: Implikasinya Terhadap Akses Layanan Kesehatan Masyarakat Miskin Yang Rendah, Dewi Rokhmah

Kesmas

Saat ini, fokus utama dari pelayanan kesehatan masih bertumpu pada aspek medis yang sangat kurang memperhatikan isu sosial termasuk gender yang merupakan penyebab utama kesenjangan bidang kesehatan di masyarakat kita. Tuberkulosis adalah penyakit yang menyebabkan kematian di seluruh dunia. Gender berperan sebagai salah satu determinan penyakit tuberkulosis meliputi penemuan kasus, diagnosis, dan proses pengobatan. Penelitian ini bertujuan menganalisis perspektif gender pencapaian Program Tuberkulosis Directly Observed Treatment Short-course (DOTS) meliputi penemuan, diagnosis pasien, dan hasil pengobatan di Rumah Sakit Paru Jember, tahun 2010. Penelitian ini menggunakan metode deskriptif analitik menggunakan data sekunder yang berasal dari Laporan Program Tuberkulosis DOTS Tahun 2010. …

Faktor Risiko Kematian Ibu, Nurul Aeni

Kesmas

Angka Kematian Ibu (AKI) di Kabupaten Pati bergerak fluktuatif dan menunjukkan status tertinggi pada tahun 2011 dengan 126 per 100.000 kelahiran hidup. Tujuan penelitian ini adalah menggambarkan kematian ibu di Kabupaten Pati dan menganalisis faktor risiko kematian maternal di Kabupaten Pati Tahun 2011. Penelitian menggunakan pendekatan observasional analitik dengan metode kasus kontrol. Jumlah sampel adalah 24 untuk setiap kelompok kasus dan kelompok kontrol. Analisis data menggunakan uji univariat, bivariat dan multivariat. Hasil dari penelitian adalah tiga penyebab utama kematian ibu di Kabupaten Pati adalah penyakit jantung, preeklamsi/eklamsi, dan perdarahan. Kematian ibu tersebar di 16 kecamatan dari 21 kecamatan yang ada …

Partisipasi Semu Ibu Hamil Di Posyandu, Shrimarti Rukmini Devy, Muhammad Hakimi, Yayi Suryo Prabandari, Totok Mardikanto, Dhody Rafsandjani, Sofyan Haryanto

Kesmas

Salah satu kebijakan pembangunan bidang kesehatan yang dipergunakan untuk mengatasi kesehatan ibu hamil adalah pemberdayaan masyarakat. Keberhasilan pemberdayaan dapat diketahui melalui berbagai cara, salah satunya partisipasi masyarakat. Penelitian ini bertujuan untuk mengidentifikasi kondisi sosial, budaya, dan ekonomi yang mempengaruhi partisipasi ibu hamil ke posyandu. Penelitian ini menggunakan rancangan etnografi. Teknik yang digunakan untuk pengumpulan data adalah wawancara mendalam, focus group discussion, observasi dan nominal group process. Data yang diperoleh dari pendekatan kualitatif akan diolah dengan content analysis. Hasil penelitian ini menunjukkan kondisi sosial, budaya dan ekonomi yang mempengaruhi partisipasi ibu hamil ke posyandu di Desa Rapa Laok, bermula pada faktor …

Pengetahuan Dan Ekspresi Emosi Keluarga Serta Frekuensi Kekambuhan Penderita Skizofrenia, Surya Mulya Fadli, Mitra Mitra

Kesmas

Skizofrenia merupakan gangguan psikotik yang bersifat kronis dan selalu mengalami kekambuhan. Tujuan penelitian adalah untuk mengetahui hubungan faktor keluarga dan kepatuhan minum obat dengan kekambuhan penderita skizofrenia di Rumah Sakit Jiwa Tampan Provinsi Riau tahun 2012. Desain penelitian ini adalah cross sectional study dengan ukuran sampel adalah 50 responden dari keluarga penderita skizofrenia yang berkunjung di poliklinik rawat jalan Rumah Sakit Jiwa Tampan. Analisis data dilakukan secara univariat, bivariat dengan korelasi, regresi linier sederhana, dan uji t independen, multivariat dengan uji regresi linier ganda. Variabel yang berhubungan dengan frekuensi kekambuhan penderita skizofrenia adalah pengetahuan keluarga dan ekspresi emosi keluarga. Pengetahuan …

Hannah Arendt And Pregnancy In The Public Sphere, Katy Fulfer

Future Directions in Feminist Phenomenology

No abstract provided.

Feminist Bio-Phenomenology, Christina Schües

Future Directions in Feminist Phenomenology

No abstract provided.

Body Talk I: Habituation To Bodily Changes After Breast Surgery In Women, Jenny Slatman

Future Directions in Feminist Phenomenology

No abstract provided.

Optimizing The Value Of Public Health Services: Lessons From Research & Practice, Glen P. Mays

Health Management and Policy Presentations

Expanding the delivery of efficacious public health programs and policies holds considerable potential for improving population health and constraining the growth in health care spending. Achieving such expansions efficiently, particularly in low-resource settings, requires careful attention to interorganizational and intergovernmental relationships in public health delivery.

Today - May 24, 2013, Loma Linda University Health

TODAY

Inside this issue:

-- Commencement 2013 speakers announced
-- First 5 Riverside grants $7.5 million to School of Dentistry
-- Leading scholars present symposium at LLU: Entrusted - Christians and Environmental Care
-- Second annual The Old Spaghetti Factory Tip-a-Firefighter event raises funds for LLU Children's Hospital
-- Researchers from LLU and UCLA study ethnicity and mental health treatment
-- MBA team reveals health care knowledge curing competition at Cal State
-- First pediatric surgery fellow complete program at LLU Children's Hospital
-- Apprenticeship Bridge to College event draws future students to LLU
-- Campus-wide disaster drill simulates Code Silver …

Comprehensive Behavioral Characterization Of An App/Ps-1 Double Knock-In Mouse Model Of Alzheimer's Disease, Scott J. Webster, Adam D. Bachstetter, Linda J. Van Eldik

Sanders-Brown Center on Aging Faculty Publications

INTRODUCTION: Despite the extensive mechanistic and pathological characterization of the amyloid precursor protein (APP)/presenilin-1 (PS-1) knock-in mouse model of Alzheimer's disease (AD), very little is known about the AD-relevant behavioral deficits in this model. Characterization of the baseline behavioral performance in a variety of functional tasks and identification of the temporal onset of behavioral impairments are important to provide a foundation for future preclinical testing of AD therapeutics. Here we perform a comprehensive behavioral characterization of this model, discuss how the observed behavior correlates with the mechanistic and pathological observations of others, and compare this model with other commonly used …

Epidemiology News, Georgia Southern University

Biostatistics, Epidemiology & Environmental Health Sciences: News & Publications (2011-2018)

• Caring for Haitian Orphans with Aids

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Caring for Haitian Orphans with Aids

Do We Need To Shock The World To Strengthen The Huntington's Disease Cause, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

The Santa Clara, 2013-05-23, Santa Clara University

The Santa Clara

No abstract provided.

Microproteinuria During Opisthorchis Viverrini Infection: A Biomarker For Advanced Renal And Hepatobiliary Pathologies From Chronic Opisthorchiasis, Prasert Saichua, Paiboon Sithithaworn, Amar R. Jariwala, David J. Diemert, Jiraporn Sithithaworn, Banchob Sripa, Thewarach Laha, Eimorn Mairiang, Chawalit Pairojkul, Maria V. Periago, Narong Khuntikeo, Jason Mulvenna, Jeffrey M. Bethony

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Approximately 680 million people are at risk of infection with Opisthorchis viverrini (OV) andClonorchis sinensis, with an estimated 10 million infected with OV in Southeast Asia alone. While opisthorchiasis is associated with hepatobiliary pathologies, such as advanced periductal fibrosis (APF) and cholangiocarcinoma (CCA), animal models of OV infection show that immune-complex glomerulonephritis is an important renal pathology that develops simultaneously with hepatobiliary pathologies. A cardinal sign of immune-complex glomerulonephritis is the urinary excretion of immunoglobulin G (IgG) (microproteinuria). In community-based studies in OV endemic areas along the Chi River in northeastern Thailand, we observed that over half of …

Fearless: Kevin Lugo, Kevin B. Lugo

SURGE

This summer, recent graduate Kevin Lugo will bike over 4,000 miles across the country to benefit the Ulman Cancer Fund for Young Adults. His choice to bike for seventy days from Baltimore to Seattle makes him fearless! His goal is to raise $7,476 for the organization, and he reached that goal last night (although more donations are always welcome in support of fighting cancer)! Kevin explains that when he studied abroad in Denmark in the fall of 2011, he “fell in love with sustainable transportation, especially cycling.” Not only does his fearless endeavor raise money to fight cancer, but he …

Selection Of A Non-Phosphorylated Peptide Inhibitor Of Brca1’S (Brct)2 Domain, Railey White

Theses and Dissertations

A growing body of literature suggests Breast Cancer-Associated Protein 1 (BRCA1) is important not only as a cause, but also as a target in the quest for cancer treatment. BRCA1 deficient cells treated with radiation as well as PARP inhibitors and other chemotherapeutics demonstrate a greater sensitivity than cells with wild type BRCA1. Inhibitors of BRCA1 would take advantage of this synthetic lethality and represent a significant advance in cancer treatment as well as an understanding of the biology of DNA repair. Despite significant study of BRCA1 protein and function, it is a large protein (220 KDa) that is still …

The Effects Of Practice On The Concurrent Performance Of A Speech And Postural Task In Persons With Parkinson Disease And Healthy Controls, K. Bo Foreman, Stuart Sondrup, Christopher Dromey, Eon Jarvis, Shawn Nissen, Leland E. Dibble

Faculty Publications

Purpose. Persons with Parkinson disease (PD) demonstrate deficits in motor learning as well as bidirectional interference (the performance of one task concurrently interferes with the performance of another task) during dual-task performance. Few studies have examined the practice dosages necessary for behavioral change in rehabilitation relevant tasks. Therefore, to compare the effects of age and PD on motor learning during dual-task performance, this pilot study examined persons with PD as well as neurologically healthy participants during concurrent performance of postural and speaking tasks. Methods. Seven persons with PD and 7 healthy age-matched and 10 healthy young control subjects …

Carter, Tim Lee, 1910-1987 (Mss 80), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid only for Manuscripts Collection 80. Correspondence, photographs, audiotapes, film, clippings, general office files, and records of legislative proceedings relating to the political career of Tim Lee Carter, U.S. Representative (Republican) for Kentucky's Fifth Congressional District, 1965-1981.

Cannabis And Psychosis: Transition To Psychosis, Amresh Srivastava, Kristen , Terpstra, Yves Bureau

Data and Test Instruments

Cannabis has been implicated as a risk factor for the development of schizophrenia, however, but the pathway of cannabis causing psychosis is not well understood. It appears that cannabis does not cause any structural changes per say but deficits in areas of the brain responsible for memory and emotion do show some changes. Recent studies suggest that cannabinoids such as CB1 have a pharmacological profile similar to that of atypical antipsychotic drugs. This mechanisms may involve dopamine, GABA, and glutamate neurotransmission; It is still not known if these changes are transitory or permanent, and whether or not they contribute to …

Resilience, Psychopathology And Rehospitalization, Amresh Srivastava

Data and Test Instruments

Purpose: The goal of the project was to determine why patients are being hospitalized repeatedly within an acute psychiatric facility. Past studies have found repeated hospitalization leads to economic drain, disability, poor outcome, stigma and discrimination. Repeated hospitalizations are one of the main causes of disability and dysfunction amongst the mentally ill as well as consuming more than 90 % of the mental health budget. This drain deprives consumers of a major part of allocated health resources. Identifying the potential risk factors for repeated hospitalization, interrelationships between risk factors, and vulnerability will help us take the appropriate measures to prevent …

Cultural Aspects Of Latino Early Childhood Obesity, Lauren Clark, Susan L. Johnson, Mary E. O'Connor, Jane H. Lassetter

Faculty Publications

The problem of Latino childhood obesity is well known, and experts agree that the sooner it is addressed in a child’s life, the better. Strong evidence from nationwide studies suggests that obesity begins in infancy for Mexican Americans. National data demonstrate the dramatic increase in weight-for-recumbent length above the 95th percentile (using the NCHS growth chart) among Mexican American children between National Health and Nutrition Examination Survey (NHANES) and the Third National Health and Nutrition Examination Survey (NHANES III) (Ogden et al., 2006). High rates of childhood obesity affect the long-term health potential of children, since childhood obesity tracks into …

Interventions Pour La Prévention Des Tms : Mesure De L’Exposition Aux Facteurs De Risque Et Aspects Économiques, Daniel Imbeau, Marie-Ève Chiasson, Romain Jallon, Bruno Farbos, Karine Aubry, Nathalie De Marcellis-Warin, Marie St-Vincent

Rapports de recherche scientifique

Les troubles musculo-squelettiques (TMS) au dos et aux membres supérieurs constituent un problème majeur ayant des retombées au point de vue humain, social et économique. Ainsi, au cours des dernières années, plusieurs méthodes d'évaluation de l'exposition aux facteurs de risque (MÉEFR) de TMS ont été proposées par la communauté scientifique afin de soutenir les efforts de prévention. Toutefois, relativement peu d'information existe sur l'utilisation pratique de ces différentes méthodes en milieu de travail. Celles-ci sont nombreuses, ce qui complique pour le praticien le choix d'une méthode appropriée au contexte de l'intervention. Aussi, l'évaluation économique d'une intervention en SST est un …

Relations Between Oral Pharyngeal Size And Kinematic Measures Of Tongue Related Swallowing Movements, Danielle Monast

Honors Theses

Background: Though the tongue plays a critical role during the oral phase of swallowing, studies have found that the size and shape of tongue movements during swallowing can vary greatly among individuals. One factor that may contribute to this movement variability is oral-pharyngeal cavity geometry. A cavity with a different size and shape may require different movements for efficient swallowing. While there are a number of studies that have attempted to relate the oral-pharyngeal anatomy with features of orofacial movement, these studies focused on speech movements and no studies have directly evaluated the relation between swallowing related tongue movements and …

Examining Universal Primary Healthcare Through Community-Based Initiatives, Donald E. Warden

Oglethorpe Journal of Undergraduate Research

This paper examines enacting community-based primary healthcare programs and initiatives. It looks at the weaknesses of past attempts, the successes of current attempts, and gives insight into ways everyday citizens can change the way the world does healthcare. There are social, economic, and political barriers as to why these programs are not enacted. Since 1978, Member states of the United Nations strive towards healthcare for all. The original 1978 Declaration of Alma-Ata sets the bar at achieving this goal by the year 2000. Now in the 21^st century, the world still battles inadequate healthcare. Nations continue to strive towards …