Medicine and Health Sciences Commons^™

Dementia And Technology: Evidence Supporting Assistive Technology For Individuals With Alzheimer’S Disease And Related Dementias, Diana Skoutelas, Christine Tanner, Gabriella Vulpis, Gittel Zelczer

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

The prevalence of Alzheimer’s disease in the Unites States is estimated to be 5.2 million (Alzheimer’s Association, 2013). Alzheimer’s disease and related dementias (ADRD) can impact an individual’s ability to independently participate in daily occupations within their environment due to executive dysfunction, memory loss, poor judgment, and decreased problem solving (Desai, Grossberg, & Sheth, 2004; Alzheimer’s Association, 2013). Due to the rising prevalence of dementia, Labelle and Mihailidis (2006) note the importance of occupational therapists finding innovative and evidence-based strategies to enable participation in daily occupations. The purpose of this presentation is to present the results of a literature review …

Thinking Through The Chemo-Fog: Occupational Therapy’S Role In Promoting Participation In Adults With Breast Cancer, Amanda Ally, Lisa Ferguson, Emily Grabow, Katrina Long, Alisha Sharp

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Breast cancer is currently the most common type of cancer in women (American Cancer Society, 2012). In 2012, 2,971,610 women in the United States were breast cancer survivors (American Cancer Society, 2012). Chemotherapy is often used to effectively treat breast cancer but can cause chemobrain, or chemotherapy-related cognitive impairments (CRCI), including decreased attention, concentration, memory, and difficulty learning new skills and completing routine tasks (American Cancer Society, 2013). CRCI can persist for years and may impact an individual’s occupational performance in daily activities and occupations. Occupational therapy practitioners currently work with this population in other areas including cancer-related fatigue management, …

Beyond Piecework: Employment For Persons With Intellectual And Developmental Disabilities, Kelly Brandwene, Ilese Coleman, Adva Epstein, Alyssa Peachey, Lauren Rosenthal

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

All people deserve competitive, fulfilling employment (Lysaght, Cobigo, Hamilton, 2011). Many people with intellectual or developmental disabilities (I/DD) have difficulty obtaining competitive employment despite desiring to work (Lysaght, Ouellett-Kuntz, & Lin, 2010). In past years, people with I/DD have been employed in sheltered workshops; however, they are often paid below minimum wage, do not receive benefits, and are viewed as subordinates. Workers report the desire to work outside of sheltered employment. Competitive employment (integrated/supported employment), can lead to social justice, social inclusion, personal growth, and improved financial situations (Migliore, Mank, Grossi, & Rogan, 2007). Occupational therapists are suited to assist …

Falling Into Home Mods: Occupational Therapy’S Role In Keeping Older Adults Safe At Home, Elizabeth Janeczko, Brendan Kiernan, Mary Susan Paige, Stephanie Reitemeier, Joshua Springer

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Falls are the leading cause of injury-related deaths and the most common cause of nonfatal injuries and hospital admissions for older adults aged 65 and older.¹ Other consequences of falls are increased fear of falling, and decreased independence and participation in performance of daily activities. In the past decade, evidence has identified the multifactorial approach, which includes home modification, as the most effective approach in preventing falls in older adults.² Occupational therapists have the education and unique skill set to perform client-centered home modifications. The purpose of this presentation is to describe the results of an evidenced-based literature …

Can't Hold Me Back! Constraint-Induced Movement Therapy For Children With Cp: Evidence Based Review, Rebecca Coale, Danni Eisner, Alissa Herman, Sarah Merhaut

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Children with cerebral palsy (CP) have various functional impairments impacting participation in meaningful occupations. While Constraint-Induced Movement Therapy (CIMT) is a widely used intervention for adult populations, a modified version of this technique is a relatively new practice in pediatrics (Charles et al., 2006). Occupational therapy intervention, such as CIMT, can support functional goal attainment to enhance participation and quality of life (Boyd et al., 2010). The purpose of this presentation is to synthesize results of a comprehensive evidence-based review and identify treatment characteristics that impact efficacious use of mCIMT on children with hemiplegic CP. Practitioners will learn about best …

Strengthening The Science Of Public Health Delivery Through Public Health Services Research, Glen P. Mays

Health Management and Policy Presentations

This session notes recent progress from the field of public health services and systems research (PHSSR) concerning the most promising directions for improving the delivery and impact of public health services, programs, and policies.

Clinical Effectiveness Of Motor Imagery Post-Stroke: An Evidence Based Review, Azadeh Narimanian, Amanda Reese, Karina Ryabo, Rachel Shepp, Annalisa Synnestvedt

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Following a stroke, many individuals experience participation limitations secondary to upper extremity hemiparesis (Shenn & Leishear, 2011). Motor imagery, the mental representation of movement without any body movement, is an evidenced-based intervention to optimize upper extremity function for patients following stroke (Dickstein & Deutsch, 2007). Motor imagery is a readily applicable, safe, and cost-effective intervention that can help clients achieve a variety of occupational goals within diverse environments (Guttman, Burstin, Brown, Bril, & Dickstein, 2012). The purpose of this presentation is to present the results of an evidence-based review examining the use of motor imagery to increase functional outcomes for …

Paws With A Purpose: Evidence Supporting The Use Of Animal Assisted Therapy To Improve Quality Of Life In Adults With Psychiatric Diagnoses, Julia Andraka, Lacey Brinser, Kelly D'Ambrosio, Jordan Justice, Elizabeth Rugen

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Approximately 62.7 million Americans have a psychiatric diagnosis, including Alzheimer’s disease and mental disorders^1,6. Adults who are diagnosed with these conditions experience a variety of limitations, including decreased quality of life⁴. Occupational Therapy (OT) has been shown to be an effective treatment to increase quality of life in adults with psychiatric diagnoses³. Occupational therapists working within the mental health field often need to use creative and innovative approaches to motivate their clients, including Animal-assisted therapy (AAT). AAT is a unique intervention approach that has the potential to improve a person’s emotional, physical, cognitive and …

Transitions For Tomorrow: An Evidence-Based Review Of Post-Secondary Transition Planning For Individuals With Autism, Julie Bardenwerper, James Gillette, Elizabeth Luk, Hilary Moser, Alanna Raffel

Collaborative Research and Evidence shared Among Therapists and Educators (CREATE Day)

Autism spectrum disorder (ASD) is the fastest growing neurodevelopmental disability in the US other than ADHD (IACC, 2012). Currently, the prevalence of individuals with ASD is estimated to be 1 in 88 in the US (CDC, 2012). Therefore, increasing numbers of children with ASD will age out of high school and transition to postsecondary settings. Individuals with ASD have demonstrated less successful postsecondary outcomes than individuals with other disabilities (Shattuck et al., 2011). Currently, there is limited research supporting the methods of successful transition planning for students with ASD (IACC, 2012). The purpose of this presentation is to introduce the …

Effects Of Tobacco Industry Marketing Practices On Adolescents, Eric L. Perry

Journal of Undergraduate Research

After many years of intense controversy and debate about tobacco and its marketing, a landmark settlement occurred in 1998 between 46 U.S. states and producers of tobacco products. The agreement states that tobacco companies must spend $246 billion over the next 25 years to settle health claims. The settlement also demanded companies put a senior vice-president over youth smoking prevention activities. The way that tobacco firms have responded to this last edict continues to be hotly contested.

The Efficacy Of Social Language Intervention On Children With Specific Language Impairment—A Pilot Study, Sarah Johnson Mueller, Dr. Martin Fujiki

Journal of Undergraduate Research

In this pilot study, I investigated the efficacy of an experimental social skills intervention program for children with Specific Language Impairment (SLI). As there is a limited amount of research related to the treatment of the social skills of these children, it was my hope that such a pilot study would supply important information for future research in this area. For my research, I evaluated whether a specialized social skills intervention program produced improved social interactions in 4 children with SLI. To do this, I studied the behavioral changes of children in both a traditional language intervention group and a …

Positive Youth Development, Life Satisfaction, And Problem Behaviors Of Adolescents In Intact And Non-Intact Families In Hong Kong, Daniel T. L. Shek, Hildie Leung

Pediatrics Faculty Publications

This study investigated whether Chinese adolescents living in intact and non-intact families differed in their positive development, life satisfaction, and risk behavior. A total of 3,328 Secondary 1 students responded to measures of positive youth development (such as resilience and psychosocial competencies), life satisfaction, and risk behavior (substance abuse, delinquency, Internet addiction, consumption of pornographic materials, self-harm, and behavioral intention to engage in problem behavior). Findings revealed that adolescents growing up in intact families reported higher levels of positive developmental outcomes and life satisfaction as compared with adolescents from non-intact families. Adolescents in non-intact families also reported higher levels of …

Cytotoxicity Study Of Iron Oxide Nanoparticles, Single-Wall Carbon Nanotubes And Their Complexes Applied To Mcf7 Breast Cancer Cells, Karine Mege

Theses and Dissertations

Reactive Oxygen Species (ROS) are radicals of great concern to biologists. Their role in several diseases--such as neurodegenerative disease, diabetes, premature aging and cancer--has been intensively investigated during the last decade. Since a major focus in cancer research is to better understand how it is induced and therefore how it can be cured, the study of the cytotoxic effects of ROS production within cancer cells is vital. Nanotechnology is an emerging field of science that promises great improvements in a number of disciplines. Nano medicine is one of its daughter fields. Various nanomaterials are used for diagnosis and disease detection, …

Fecal Transplantation Does Not Transfer Either Susceptibility Or Resistance To Food Borne Listeriosis In C57bl/6 And Balb/C/By Mice, Tanya Myers-Morales, Kate M. Bussell, Sarah E. F. D'Orazio

Microbiology, Immunology, and Molecular Genetics Faculty Publications

The composition of the intestinal microbiota has wide reaching effects on the health of an individual, including the development of protective innate immune responses. In this report, a fecal transplantation approach was used to determine whether resistance to food borne listeriosis was dependent on the murine gut microbiota. Transplantation of BALB/c/By feces did not increase the susceptibility of C57BL/6 mice to Listeria monocytogenes infection. Likewise, transplantation of C57BL/6 fecal matter did not enhance the resistance of BALB/c/By mice. Thus, intestinal microbiota composition is not a key factor that confers either susceptibility or resistance to food borne listeriosis in mice.

Cultural Competence Of Taiwanese Nurses, Chin-Nu Lin

Nursing Theses and Dissertations

Research on the cultural competence in nursing care in Taiwan is scarce. Little information has been documented regarding the level of cultural competence among its health care professionals. The aim of this study was to investigate the level of cultural competence among Taiwanese nurses. This study employed a quantitative design using a self-report online survey. Research findings indicated that Taiwanese nurses had low to moderate level of cultural competence. They perceived themselves as being not culturally competent when caring for clients from culturally and ethnically diverse backgrounds. While Taiwanese nurses scored high on cultural sensitivity and awareness, they scored low …

The Drug Facts Box: Improving The Communication Of Prescription Drug Information, Lisa M. Schwartz, Steven Woloshin

Dartmouth Scholarship

Communication about prescription drugs ought to be a paragon of public science communication. Unfortunately, it is not. Consumers see $4 billion of direct-to-consumer advertising annually, which typically fails to present data about how well drugs work. The professional label—the Food and Drug Administration's (FDA) mechanism to get physicians information needed for appropriate prescribing—may also fail to present benefit data. FDA labeling guidance, in fact, suggests that industry omit bene

Millet Family History, “A Brief History Of Artemus Millet, “ Ms., 70-71 Lds Church Archives., Kristen Proctor, Dr. Gordon Lindsay

Journal of Undergraduate Research

In the fall of 1999, I developed a proposal to research the effects of literacy and education on the health and socioeconomic status of women in rural Mexico. Shortly thereafter, I was asked to facilitate a group of student volunteers going to the Dominican Republic (D.R.) as a part of a collaboration between Latter-day Saint Charities,

Regulation Of Cell Death By Transfer Rna., Ya-Ming Hou, Xiaolu Yang

Department of Biochemistry and Molecular Biology Faculty Papers

SIGNIFICANCE: Both transfer RNA (tRNA) and cytochrome c are essential molecules for the survival of cells. tRNA decodes mRNA codons into amino-acid-building blocks in protein in all organisms, whereas cytochrome c functions in the electron transport chain that powers ATP synthesis in mitochondrion-containing eukaryotes. Additionally, in vertebrates, cytochrome c that is released from mitochondria is a potent inducer of apoptosis, activating apoptotic proteins (caspases) in the cytoplasm to dismantle cells. A better understanding of both tRNA and cytochrome c is essential for an insight into the regulation of cell life and death.

RECENT ADVANCES: A recent study showed that the …

Ada News - 08/19/2013, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

What's Happening: August 19, 2013, Maine Medical Center

What's Happening

No abstract provided.

Daily Needs Of Family Members Of Icu Patients With Severe Traumatic Brain Injury, Christy Rae Lee, Dr. A. Elaine Bond

Journal of Undergraduate Research

In the intensive care unit (ICU), family members of severe traumatic brain-injured (STBI) patients struggle with the possibility of future dysfunction or untimely death. This is a vulnerable and precarious time for the families. In this crisis time, nurses must be able to provide holistic nursing care that includes the family as well as the patient. To determine and react to the family’s ongoing needs, nurses could return some stability to the family, aiding the patient’s recovery.

Childbirth Experience Of Chinese Women, Robin Kartchner, Dr. Lynn C. Callister

Journal of Undergraduate Research

Women across the world share in the same biological process of childbirth. However, their experience with childbirth can vary widely depending on their cultural and spiritual background. The quality of care a woman receives during and after her pregnancy is deeply influenced by the understanding of these factors that the nurse brings to their interaction (1). This research built on previous studies of women from other cultures (2) by interviewing Chinese women in China about their childbirth experience.

An Educational Approach: Increasing College Freshmen's Knowledge Regarding Sexually Transmitted Infections, Jennie Mcclain

Evidence-Based Practice Project Reports

According to the Centers for Disease Control (2009), young adults account for only 25% o fsexually active persons in the United States, but account for 50% of the newly diagnosed cases of sexually transmitted infections (STIs). Some young adults may not have received appropriate or credible information on sexual health by which to make knowledgeable decisions that may influence the rest of their lives. High schools are not required to offer comprehensive sex education. Therefore, some students may have received abstinence-only sex education. Risk reduction and disease prevention are important in college health. This evidenced-based practice project included the creation, …

Calpain-2 Compensation Promotes Angiotensin Ii-Induced Ascending And Abdominal Aortic Aneurysms In Calpain-1 Deficient Mice, Venkateswaran Subramanian, Jessica J. Moorleghen, Anju Balakrishnan, Deborah A. Howatt, Athar H. Chishti, Haruhito A. Uchida

Saha Cardiovascular Research Center Faculty Publications

BACKGROUND AND OBJECTIVE: Recently, we demonstrated that angiotensin II (AngII)-infusion profoundly increased both aortic protein and activity of calpains, calcium-activated cysteine proteases, in mice. In addition, pharmacological inhibition of calpain attenuated AngII-induced abdominal aortic aneurysm (AA) in mice. Recent studies have shown that AngII infusion into mice leads to aneurysmal formation localized to the ascending aorta. However, the precise functional contribution of calpain isoforms (-1 or -2) in AngII-induced abdominal AA formation is not known. Similarly, a functional role of calpain in AngII-induced ascending AA remains to be defined. Using BDA-410, an inhibitor of calpains, and calpain-1 genetic deficient mice, …

Plasma S-Adenosylmethionine, Dnmt Polymorphisms, And Peripheral Blood Line-1 Methylation Among Healthy Chinese Adults In Singapore, Maki Inoue-Choi, Heather H. Nelson, Kim Robien, Erland Arning, Teodoro Bottiglieri, Woon-Puay Koh, Jian-Min Yuan

Epidemiology Faculty Publications

Background

Global hypomethylation of repetitive DNA sequences is believed to occur early in tumorigenesis. There is a great interest in identifying factors that contribute to global DNA hypomethylation and associated cancer risk. We tested the hypothesis that plasma S-adenosylmethionine (SAM) level alone or in combination with genetic variation in DNA methyltransferases (DNMT1, DNMT3A andDNMT3B) was associated with global DNA methylation extent at long interspersed nucleotide element-1 (LINE-1) sequences.

Methods

Plasma SAM level and LINE-1 DNA methylation index were measured using stored blood samples collected from 440 healthy Singaporean Chinese adults during 1994-1999. Genetic polymorphisms of …

Net Reclassification Indices For Evaluating Risk Prediction Instruments: A Critical Review, Kathleen F. Kerr, Zheyu Wang, Holly Janes, Robyn Mcclelland, Bruce M. Psaty, Margaret S. Pepe

UW Biostatistics Working Paper Series

Background Net Reclassification Indices (NRI) have recently become popular statistics for measuring the prediction increment of new biomarkers.

Methods In this review, we examine the various types of NRI statistics and their correct interpretations. We evaluate the advantages and disadvantages of the NRI approach. For pre-defined risk categories, we relate NRI to existing measures of the prediction increment. We also consider statistical methodology for constructing confidence intervals for NRI statistics and evaluate the merits of NRI-based hypothesis testing.

Conclusions Investigators using NRI statistics should report them separately for events (cases) and nonevents (controls). When there are two risk categories, the …

Allostatic Load Amplifies The Effect Of Blood Lead Levels On Elevated Blood Pressure Among Middle-Aged U.S. Adults: A Cross-Sectional Study, Ami R. Zota, Edmond R. Shenassa, Rachel Morello-Frosch

Environmental and Occupational Health Faculty Publications

Background

Scientists and regulators have sought to understand whether and how physiologic dysregulation due to chronic stress exposure may enhance vulnerability to the adverse health effects of toxicant exposures. We conducted a cross-sectional study to determine whether allostatic load (AL), a composite measure of physiologic response to chronic exposure to stress, amplifies the effect of lead exposure on blood pressure among middle-aged adults.

Methods

We analyzed associations between blood lead levels and blood pressure in a nationally representative sample of 8,194 U.S. adults (aged 40-65 years) participating in the National Health and Nutritional Examination Survey, 1999--2008. Outcomes were elevated systolic …

Dose- And Time-Dependent Neuroprotective Effects Of Pycnogenol® Following Traumatic Brain Injury, Mubeen A. Ansari, Kelly N. Roberts, Stephen W. Scheff

Sanders-Brown Center on Aging Faculty Publications

After traumatic brain injury (TBI), both primary and secondary injury cascades are initiated, leading to neuronal death and cognitive dysfunction. We have previously shown that the combinational bioflavonoid, Pycnogenol® (PYC), alters some secondary injury cascades and protects synaptic proteins when administered immediately following trauma. The purpose of the present study was to explore further the beneficial effects of PYC and to test whether it can be used in a more clinically relevant fashion. Young adult male Sprague-Dawley rats were subjected to a unilateral moderate/severe cortical contusion. Subjects received a single intravenous (i.v.) injection of PYC (1, 5, or 10 mg/kg) …

A Look At The Changes In Public Awareness Of Aids In The United States From 1987-1994, Kimberly Barlow-Miller, Dr. Ray Merrill

Journal of Undergraduate Research

In 1980-81, five homosexual men in California were found to have a strain of pneumonia normally found only in the suppressed immune systems of the elderly. They were later diagnosed with the first cases of a rare and new disease known as Acquired Immune Deficiency Syndrome (AIDS). This event has brought about a greater awareness of the AIDS disease among the population of the United States, as evidenced in the results of the AIDS supplement sections of the National Health Interview Survey (NHIS) from 1987 to 1994. Using questions asked of a representative sample of the US population, our research …

Preferred Channels Of Communication For Emergency Preparation, Rainie Graham, Dr. Michael D. Barnes

Journal of Undergraduate Research

This report is written as a summary of the research that was conducted throughout the winter and spring of 2000 in support of the funded research proposal titled “Channels of Communication for Emergency Preparation”. This research was intended to establish the preferred communication channels for receiving emergency preparedness information by married students attending BYU. The BYU Institutional Research Office compiled a randomly selected list of 395 students’ electronic addresses. A simple random selection was used for the sampling strategy, to select students who were married and attending the Spring Term at BYU.