Medicine and Health Sciences Commons^™

Birth Methods And The Incidence Of Sudden Infant Death Syndrome-Sids, Luiz H. Meneghin, Dr. Debra Hobbins

Journal of Undergraduate Research

Sudden Infant Death Syndrome (SIDS), also called crib death, refers to the sudden, unexpected death of any infant or young child in whom a postmortem examination fails to demonstrate a cause for death. It is the greatest single cause of death among infants between 1 week and 1 year of age.1 Many studies have identified risk factors associated with SIDS (low birth weight, preterm delivery, maternal smoking, winter months, positioning during sleep, male gender, etc.), however, no studies were found regarding the method of birth and the incidence of SIDS. The purpose of this study was to investigate the correlation …

Today - September 20, 2013, Loma Linda University Health

TODAY

Inside this issue:

-- LLU Health to receive nearly $1 million to help people access affordable health care
-- Children's Hospital patient lobbies U.S. Congress
-- Disaster drill prepares campuses for hazardous chemical release
-- Interweave: The Wholeness Story
-- Regional clergy invited to join Faith Community Health Network
-- Dentistry professor named Pierre Fauchard Teacher of the Year
-- LLUMC orthopedic surgeon repairs legs for Nigerian girl
-- New task force forms to promote NIH Center of Excellence
-- LLU Health representatives at ASI Convention in Orlando
-- Monthly lunch seminars keep researchers apprised of trends
-- LLUH to …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Adults Attitudes toward Teen Pregnancy

The Impact Of Feeding Methods And Hiv On Infants In Bolivia, Neal Peterson, Dr. Kirk Dearden

Journal of Undergraduate Research

Over the last several decades in Latin America there has been a shift from exclusive breastfeeding (no foods or liquids other than breastmilk) to replacement feeding (foods and liquids in addition to or other than breastmilk). Whether because of social stigma or lack of time, mothers are increasingly turning to alternative feeding methods. Studies by various scientists have shown that exclusive breastfeeding is the most beneficial method of infant feeding and results in less sickness and decreased infant mortality. However, given that HIV can be transmitted through breastmilk, does the increasing prevalence of HIV globally significantly contribute to increased morbidity …

Community Health News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

• Adults Attitudes toward Teen Pregnancy

Disability, Health, And Multiple Chronic Conditions Among People Eligible For Both Medicare And Medicaid, 2005–2010., Michael H. Fox, Amanda Reichard

Institute on Disability

Abstract Introduction People who are eligible for both Medicare and Medicaid (dual eligibles) and who have disabilities and multiple chronic conditions (MCC) present challenges for treatment, preventive services, and cost-effective access to care within the US health system. We sought to better understand dual eligibles and their association with MCC, accounting for sociodemographic factors inclusive of functional disability category. Methods Medical Expenditure Panel Survey (MEPS) data for 2005 through 2010 were stratified by ages 18 to 64 and 65 or older to account for unique subsets of dual eligibles. Prevalence of MCC was calculated for those with physical disabilities, physical …

Hiv-1 Nef Targets Calnexin: A Novel Mechanism Behind Nef Effects On Host Cell And Viral Proteins, Lucas Jennelle, Ruth Hunegnaw, Dmitri Sviridov, Michael I. Bukrinsky

Medicine Faculty Posters and Presentations

No abstract provided.

Proteomic Analysis Of Mismatch Repair-Mediated Alkylating Agent-Induced Dna Damage Response, Xi Chen, Yong Zhao, Guo-Min Li, Lin Guo

Toxicology and Cancer Biology Faculty Publications

BACKGROUND: Mediating DNA damage-induced apoptosis is an important genome-maintenance function of the mismatch repair (MMR) system. Defects in MMR not only cause carcinogenesis, but also render cancer cells highly resistant to chemotherapeutics, including alkylating agents. To understand the mechanisms of MMR-mediated apoptosis and MMR-deficiency-caused drug resistance, we analyze a model alkylating agent (N-methyl-N’-nitro-N-nitrosoguanidine, MNNG)-induced changes in protein phosphorylation and abundance in two cell lines, the MMR-proficient TK6 and its derivative MMR-deficient MT1.

RESULTS: Under an experimental condition that MNNG-induced apoptosis was only observed in MutSα-proficient (TK6), but not in MutSα-deficient (MT1) cells, quantitative analysis …

Effects Of Short-Term Portacaval Anastomosis On The Peripheral And Brain Disposition Of The Blood-Brain Barrier Permeability Marker Sodium Fluorescein In Rats, Imam H. Shaik, M. K. Miah, Ulrich Bickel, Reza Mehvar

Pharmacy Faculty Articles and Research

Contradictory results have been reported with regard to the effects of various models of hepatic encephalopathy on the blood-brain barrier (BBB) permeability, which may be due partly to the use of brain concentrations of BBB markers without attention to their peripheral pharmacokinetics. The purpose of the current study was to investigate the effects of short-term portacaval anastomosis (PCA), a type B model of hepatic encephalopathy, on the peripheral pharmacokinetics and brain distribution of sodium fluorescein (FL), which is a small molecule marker of BBB passive permeability. A single 25 mg/kg dose of FL was administered intravenously to 10-day PCA and …

Conference Learnings, Michele Gessner Rn, Cpn, Kelly Larue-Vassale Rn, Cpn

Patient Care Services / Nursing

No abstract provided.

Assessing The Burden Of Crime And The Criminal Sanction: A Public Health Perspective On Critical Issues In Criminal Justice, Jeremy Travis

Publications and Research

No abstract provided.

Traditional Healing Practice, Tyler Gibb

Journal of Undergraduate Research

Traditional primitive healing practices often involve medicines or treatments derived from plants or animals obtained from the local geographical region. The use of insects or closely related arthropods in primitive herbal medications is common. The practice of using arthropods in traditional healing practices was investigated among the culturally rich Ashanti healers in the village of Mampong in Ghana, West Africa. The Ashanti Tribe in Central Ghana is located in an area of lush vegetation and diverse arthropod fauna. The ‘folk-logic’, including cultural, biological, historical, religious, and environmental factors, that influences medical insect use was investigated. Significant factors influencing insect use …

District Specific Correlates For Hypertension In Kaoma And Kasama Rural Districts Of Zambia, Seter Siziya, Emmanuel Rudatsikira, Victor M. Mukonka, Olesegun Babaniyi, Peter Songolo, Adamson S. Muula

Faculty Publications

Introduction: Hypertension a major risk factor for cardiovascular disease and is the most widely recognized modifiable risk factor for this disease. There is little information on the prevalence and risk factors for hypertension in Zambia, and in particular in rural areas of the country. In order to contribute to the existing global literature on hypertension, particularly in rural Zambia, this study was conducted to determine the prevalence of hypertension and its correlates in two rural districts of Zambia, namely Kaoma and Kasama. Methods: A cross-sectional study using a modified World Health Organization (WHO) global non communicable diseases (NCD) surveillance initiative …

A Standardized Patient Counseling Rubric For A Pharmaceutical Care And Communications Course, Niambi Horton Pharmd, Kenna D. Payne Pharmd, Michelle Jernigan Pharmd, Jill Frost Pharmd, Stephen Wise Pharmd, Mary Klein Pharmd, Joel Epps Mba, H. Glenn Anderson Pharmd

Pharmaceutical Science and Research

Objective. To restructure a required pharmaceutical care and communications course to place greater emphasis on communication skills and include a high-stakes assessment.

Design. A standardized counseling rubric was developed for use throughout the pharmacy curriculum and the counseling laboratory practicals were changed to high-stakes assessments.

Assessment. An annual mid-semester and end-of-semester high-stakes patient-counseling objective structured clinical examination (OSCE) conducted prior to and after revision of the course and counseling rubric documented improvements in students’ scores. Performance on the post-course annual assessment patient counseling OSCE improved compared to that on the pre-course (p,0.001).

Conclusion. The 2010 course revision improved …

Henderson County Hazardous Materials Commodity Flow Study, Dr. Ritchie D. Taylor, Dr. Vijay Golla, Jacob Eagleson, Ethan Givan, Larry Koerber

Public Health Faculty Publications

This report presents the results of a Hazardous Materials (Hazmat) commodity flow study for Henderson County, Kentucky. Study components were conducted by Western Kentucky University in partnership with Henderson County Emergency Management (HCEM) and Henderson County Local Planning Committee (LEPC). Location of Henderson County and the City of Henderson in Kentucky are shown in Figure 1.1. In addition, data from an Audubon Parkway placard survey, conducted in July of 2013 for Daviess County, were used in the analysis for this report. Hazardous materials transported through Henderson County were monitored at the following sites during the study period: U.S. Highway 41 …

Asymmetric Dimethylarginine Blocks Nitric Oxide-Mediated Alcohol-Stimulated Cilia Beating., Todd A. Wyatt, S . M. Wells, Z . A. Alsaidi, Jane M. Devasure, E. B. Klein, Kristina L. Bailey, Joseph H. Sisson

Journal Articles: Pulmonary & Critical Care Med

The airway epithelium is exposed to alcohol during drinking through direct exhalation of volatized ethanol from the bronchial circulation. Alcohol exposure leads to a rapid increase in the cilia beat frequency (CBF) of bronchial epithelial cells followed by a chronic desensitization of cilia stimulatory responses. This effect is governed in part by the nitric oxide regulation of cyclic guanosine and adenosine monophosphate-dependent protein kinases (PKG and PKA) and is not fully understood. Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, is implicated in the pathogenesis of several pulmonary disorders. We hypothesized that the inhibition of nitric oxide synthase …

Screening For Distress In Ambulatory Oncology Patients: The Cope Project, Denise A. Sartz

Regis University Student Publications (comprehensive collection)

The purpose of this Doctorate of Nursing Practice (DNP) Capstone Project was to identify, assess, and refer patients who are experiencing an elevated level of distress as measured by the NCCN Distress Thermometer. The goal of this project was to decrease the psychosocial distress level in patients receiving chemotherapy. The primary objective of this evidence-based practice project was to decrease distress in oncology patients. The secondary objective was to formally adopt the NCCN clinical practice guidelines for distress management in ambulatory oncology patients. The NCCN Distress Thermometer (DT) was utilized to measure the distress level of ambulatory oncology patients currently …

Differential Joint-Specific Corticospinal Tract Projections Within The Cervical Enlargement, Curtis O. Asante, John H. Martin

Publications and Research

The motor cortex represents muscle and joint control and projects to spinal cord interneurons and–in many primates, including humans–motoneurons, via the corticospinal tract (CST). To examine these spinal CST anatomical mechanisms, we determined if motor cortex sites controlling individual forelimb joints project differentially to distinct cervical spinal cord territories, defined regionally and by the locations of putative last-order interneurons that were transneuronally labeled by intramuscular injection of pseudorabies virus. Motor cortex joint-specific sites were identified using intracorticalmicrostimulation. CST segmental termination fields from joint-specific sites, determined using anterograde tracers, comprised a high density core of terminations that was consistent between animals …

Parental Height And Child Growth From Birth To 2 Years In The Who Multicentre Growth Reference Study, Cutberto Garza, Elaine Borghi, Adelheid W. Onyango, Mercedes De Onis, Edward A. Frongillo Jr.

Faculty Publications

inear growth from birth to 2 years of children enrolled in the World Health Organization Multicentre Growth Reference Study was similar despite substantial parental height differences among the six study sites. Within-site variability in child length attributable to parental height was estimated by repeated measures analysis of variance using generalized linear models. This approach was also used to examine relationships among selected traits (e.g. breastfeeding duration and child morbidity) and linear growth between 6 and 24 months of age. Differences in intergenerational adult heights were evaluated within sites by comparing mid-parental heights (average of the mother's and father's heights) to …

A Content Analysis Of Media Coverage Of The Introduction Of A Smoke-Free Bylaw In Vancouver Parks And Beaches, Arezu Moshrefzadeh, Wendy Rice, Ann Pederson, Chizimuzo T.C. Okoli

Nursing Faculty Publications

The Board of Parks and Recreation in Vancouver, BC approved a smoke-free bylaw in the city's parks, beaches and recreational facilities, effective 1 September 2010. We analyzed local news coverage and portrayal of the bylaw to understand the potential influence of news media on public perception of the bylaw in order to inform the media advocacy work of public health interest groups. We compiled a data set of newspaper articles (n = 90) and conducted a quantitative content analysis to examine content related to the outdoor smoke-free policy, including article slant, topics related to smoking and tobacco control, and any …

A Comparison Of Attention Bias Paradigms Related To Insomnia, Nathaniel Maloney

Theses and Dissertations

Attentional bias to sleep related stimuli by poor sleepers has been reported as a factor in initiating and maintaining sleep disturbance. In this study, three paradigms (Flicker, Posner, and Stroop) were used in comparison to further investigate the role of attentional biases in Primary Insomnia. Participants (n=117) were split into good sleepers and poor sleepers using a median split with the Pittsburgh Insomnia Rating Scale (PIRS). Using the Center for Epidemiologic Studies Depression Scale (CES-D) as the covariate, two-way mixed modality ANCOVAs were conducted for each paradigm revealing no significant differences in word type, quality of sleep, or the interaction …

Exploring Substance Use Disorders Community Outpatient Counselors’ Experiences Treating Clients With Co-Occurring Medical Conditions: An Interpretative Phenomenological Analysis, Lauretta Cathers

Theses and Dissertations

Abstract EXPLORING SUBSTANCE USE DISORDERS COMMUNITY OUTPATIENT COUNSELORS’ EXPERIENCES TREATING CLIENTS WITH CO-OCCURRING MEDICAL CONDITIONS. AN INTERPRETATIVE PHENOMENOLOGICAL ANALYSIS Lauretta Anne Cathers, Ph.D. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University, 2013 Major Director: Amy Armstrong, PhD, Chair, Rehabilitation Counseling The Interpretative Phenomenological Analysis study presents the findings from a qualitative study examining substance use disorders (SUD) community outpatient treatment counselors’ experiences treating clients with co-occurring medical conditions. Interviews from five SUD community outpatient treatment counselors resulted in four emerging super-ordinate themes. The findings illustrate …

Mesures De Santé Et De Sécurité Du Travail Dans Les Petites Entreprises Montréalaises Embauchant Une Main-D’Œuvre Immigrante : Les Stratégies Favorables À La Prise En Charge, Sylvie Gravel, Gabrielle Legendre, Jacques Rhéaume, Gilles Séguin, Charles Gagné

Rapports de recherche scientifique

Cette étude portant sur les stratégies favorables à la prise en charge des mesures de santé et de sécurité du travail (SST) dans les petites entreprises montréalaises embauchant une main-d’œuvre immigrante est née des préoccupations des professionnels en santé au travail (SAT) du Centre de santé et de services sociaux (CSSS) de la Montagne, principal partenaire de ce projet. Dans les sociétés qui misent sur l’embauche des travailleurs immigrants pour combler leurs besoins de main-d’œuvre, la gestion des pratiques SST en contexte de diversité ethnoculturelle devient un sujet incontournable. De ces préoccupations ont émergé les questions suivantes : quels sont …

2013 September 17 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Cholinergic Enhancement Of Brain Activation In Mild Cognitive Impairment During Episodic Memory Encoding, Shannon L. Risacher, Yang Wang, Heather A. Wishart, Laura A. Rabin, Laura A. Flashman, Brenna C. Mcdonald, John D. West, Robert B. Santulli, Andrew J. Saykin

Publications and Research

Objective: To determine the physiological impact of treatment with donepezil (Aricept) on neural circuitry supporting episodic memory encoding in patients with amnestic mild cognitive impairment (MCI) using functional magnetic resonance imaging (fMRI).

Methods: Eighteen patients with MCI and 20 age-matched healthy controls (HC) were scanned twice while performing an event-related verbal episodic encoding task. MCI participants were scanned before treatment and after approximately 3 months on donepezil; HCwere untreated but rescanned at the same interval.Voxel-level analyses assessed treatment effects on activation profiles in MCI patients relative to retest changes in non-treated HC. Changes in task-related connectivity in medial temporal circuitry …

Are Your Parents To Blame? Disentangling Temperament, Parenting Style, And Schemas In The Development Of Depressive Symptoms, Jenny Delorme

Theses and Dissertations

This study examined Jeffrey Young's Schema Theory (1990; 2003) and its influence in understanding the etiological factors related to depressive symptoms. It was hypothesized that there would be significant interactions between parenting and temperament traits. It was also hypothesized that The Defectiveness and Insufficient Self Control EMSs would mediate the relationship between the significant parenting/temperament interactions and depressive symptoms. Participants were administered the Young Schema Questionnaire Short form-3 to measure the endorsement of schemas; the Beck Depression Inventory to measure symptoms of depression; the Young Parenting Inventory to measure perceived parenting; and the Adult Temperament Questionnaire to measure temperament traits. …

Method For Enhancing Specific Immunotherapies In Cancer Treatment, Peter G. Traber, William L. Redmond, Eliezer Zomer, Anatole Klyosov, Stefanie N. Linch

Technology Transfer - Patents

Methods and compositions of the invention relate to the enhancement of specific immunotherapies in cancer treatment. In particular, aspects of the invention relate to novel approaches to boost immune function using a complex carbohydrate pharmaceutical compound alone or in combination with other targeted immunotherapy to increase the efficacy of immunotherapy of cancer.

Assessment Of The Training And Continuing Education Needs Of A Regional Public Health Workforce, Bethany Kies, Amber T. Loos

Online Journal for Workforce Education and Development

A large Midwestern university recently received accreditation for its Master of Public Health (MPH) degree program from the Council on Education for Public Health (CEPH). Requirements of the accreditation include the periodic assessment of the regional public health workforce’s professional development needs and the delivery of training and continuing education to meet those needs. To that end, this study’s primary purpose was to describe the professional development needs of the regional public health workforce and to develop recommendations for the provision of professional development activities to meet those needs. Fifty-eight respondents from 27 regional public health departments and 7 regional …

Adolescence, Violence, And Public Health, Joav Merrick, Isack Kandel, Hatim A. Omar

Pediatrics Faculty Publications

No abstract provided.

Transient And Selective Suppression Of Neural Activity With Infrared Light, Michael W. Jenkins, Hui Lu, Jeffrey M. Mcmanus, Hillel J. Chiel

Faculty Scholarship

Analysis and control of neural circuitry requires the ability to selectively activate or inhibit neurons. Previous work showed that infrared laser light selectively excited neural activity in endogenous unmyelinated and myelinated axons. However, inhibition of neuronal firing with infrared light was only observed in limited cases, is not well understood and was not precisely controlled. Using an experimentally tractable unmyelinated preparation for detailed investigation and a myelinated preparation for validation, we report that it is possible to selectively and transiently inhibit electrically- initiated axonal activation, as well as to both block or enhance the propagation of action potentials of specific …