Medicine and Health Sciences Commons^™

Oncolog, Volume 58, Number 10, October 2013, Bryan Tutt, Sunni Hosemann, C. Wilcox

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Sentinel Lymph Node Dissection After Neoadjuvant Chemotherapy for Node-Positive Breast Cancer May replace Axillary Dissection for Some Patients: Sentinel lymph node dissection has become a standard staging tool for breast cancer patients with no clinical eveidence of disease in the lymph nodes
• INBRIEF: miR-200 MicroRNAs Slow Tumor Growth
• Compass: Resectable or Borderline Resectable Pancreatic Adenocarcinoma: Initial Treatment Options-Neoadjuvent chemoradiation may benefit patients with resectable disease
• HOUSE CALL: Hereditary Cancers: Genetic screening can give valuable information

The Impact Of A New Ecmo Program On Clinical Outcomes Of Patients With Acute Myocardial Infarction Complicated By Cardiogenic Shock., Shinya Unai, Md, Harrsion Pitcher, Md, Qiong Yang, Md, Nicholas Ruggiero, Md, Hitoshi Hirose, Md, Phd, Nicholas C. Cavarocchi, Md

Department of Surgery Faculty Papers

Objective:

To investigate if a new ECMO program will improve the outcome of patients who had acute myocardial infarction complicated with cardiogenic shock.

Presented 24th Annual ELSO Conference. Philadelphia, PA. Sep 19-21, 2013.

Selling Art Or Selling Out?: A Response To Selling Art: An Empirical Assessment Of Advertising On Fertility Clinics' Websites, Jody L. Madeira

Indiana Law Journal

Roundtable on Regulating Assisted Reproductive Technology 2012

Do Ceramic Femoral Heads Reduce Taper Fretting Corrosion In Hip Arthroplasty? A Retrieval Study., Steven M Kurtz, Sevi B Kocagöz, Josa A Hanzlik, Richard J Underwood, Jeremy L Gilbert, Daniel W Macdonald, Gwo-Chin Lee, Michael A Mont, Matthew J Kraay, Gregg R Klein, Javad Parvizi, Clare M Rimnac

Rothman Institute Papers

BACKGROUND: Previous studies regarding modular head-neck taper corrosion were largely based on cobalt chrome (CoCr) alloy femoral heads. Less is known about head-neck taper corrosion with ceramic femoral heads.

QUESTIONS/PURPOSES: We asked (1) whether ceramic heads resulted in less taper corrosion than CoCr heads; (2) what device and patient factors influence taper fretting corrosion; and (3) whether the mechanism of taper fretting corrosion in ceramic heads differs from that in CoCr heads.

METHODS: One hundred femoral head-stem pairs were analyzed for evidence of fretting and corrosion using a visual scoring technique based on the severity and extent of fretting and …

The Cutting Edge Fall 2013, Wright State University Department Of Surgery

The Cutting Edge Newsletter

An eight page newsletter created by the Department of Surgery documenting current affairs of the department. This issue highlights the completion of the School of Medicine's five-year strategic plan, faculty news, updates from the Division of Research, and more.

Difficult Airway In A Patient With Tracheal Stenosis, Stanlies D'Souza

All Scholarly Works

No abstract provided.

Femur Surgery In Multi-System Atrophy, Stanlies D'Souza

All Scholarly Works

No abstract provided.

A Case Of Cesarean Hysterectomy For Placenta Previa And Percreta, Stanlies D'Souza

All Scholarly Works

No abstract provided.

Thoracic Neuraxial Anesthesia For Lumbar Spine Decompressive Surgery, Stanlies D'Souza

All Scholarly Works

No abstract provided.

Measuring Global Coherence In Aphasia, V. Galetto, S. Kintz, T. West, Heather Harris Wright, Gerasimos Fergadiotis

Speech and Hearing Sciences Faculty Publications and Presentations

Discourse coherence may be conceptualized as representing the listener's ability to interpret the overall meaning conveyed by the speaker. Discourse schemas serve as the organizing frameworks for placing the essential discourse elements within a language sample (Bloom, Borod, & Santschi-Haywoor, Pick, & Obler, 1996; Peterson & McCabe, 1983). When the essential elements are provided a logical consistency of the discourse schema is maintained and the listener perceives the discourse as coherent (Ditman & Kuperberg, 2010; Trabasso, van den Broek, & Suh, 1989; van den Broek, Virtue, Everson, Tzeng, & Sung, 2002). Global coherence refers to the ability to semantically relate …

Tossing The Coin For Half Life, William L. Romine

Biological Sciences Faculty Publications

No abstract provided.

All Hands On Deck: A Team Approach To System Migration, Jolinda Thompson, Christopher D. Cook, Steven W. Brown, Catherine M. Sluder, Alicia Pinkney, Laura E. Abate, Meaghan Corbett

Himmelfarb Library Faculty Posters and Presentations

Purpose: To determine if a team approach to a complex integrated library system (ILS) migration would result in a timely and successful outcome.

Brief Description: Changing needs and an aging integrated library system server platform prompted Himmelfarb Health Sciences Library to migrate to a new ILS. After considering several options, Himmelfarb decided to join with the George Washington University's Jacob Burns Law Library in their move to a hosted instance of Innovative Interface's Sierra ILS and Encore OPAC.

Though some separation of data and functionality could be achieved, there were several functions that would be shared between the two libraries' …

You Can Do That In A Library? Building Sound Minds And Healthy Bodies, Alexandra Gomes, Gisela Butera, Laura E. Abate

Himmelfarb Library Faculty Posters and Presentations

Recognizing that while medical students are learning to care for others, they are often taking poor care of themselves, librarians at the George Washington University's Himmelfarb Health Sciences Library developed a three-pronged Healthy Living initiative, launched in the fall 2012 semester. Focusing on diet/nutrition, exercise, and stress reduction, the initiative included new collections and multiple activities with partners from both on and off-campus.

The Himmelfarb Library Annual Art Show: Celebrating The Creative Abilities Of Faculty, Staff, And Students, Christopher D. Cook, Kelly Knight, Elaine Sullo

Himmelfarb Library Faculty Posters and Presentations

Himmelfarb Health Sciences Library at the George Washington University has held an annual art show since 1987. Students, staff, faculty, and clinicians from the School of Medicine and Health Sciences, the School of Public Health and Health Services, the School of Nursing, the GW Hospital, and Himmelfarb Health Sciences Library are invited to submit artwork to be displayed throughout the first floor of the library in a month-long display. The talent of the artists is celebrated at an opening reception where light refreshments are served and students, staff, and faculty mingle and view the art.

Library art shows serve as …

Past, Present, And Future: Create A Library Video To Promote Outreach And Marketing!, Gisela Butera, Alicia Pinkney, Alexandra Gomes

Himmelfarb Library Faculty Posters and Presentations

In the fall of 2011, the Himmelfarb Health Sciences Library Marketing Committee was tasked with creating a video on the history of the library. As the project developed, a broader scope was outlined to capture not only our past but our current staff, services, and programs with a goal of using it for outreach. The final video project was completed in Spring 2012.

A Gender Gap Grade Analysis Of Hard Sciences Courses In A School Of Pharmacy, Mckenzie C. Ferguson, Cathy Santanello, Erika Hahn, Ron Worthington

Pharmacy Faculty Research, Scholarship, and Creative Activity

A student survey was conducted to determine perceptions of such things as differential treatment due to gender, level of preparedness for courses in the hard sciences, and gender performances of students in the sciences. Additionally, students’ grades of sixteen courses with a heavy hard science focus were analyzed by taking the percent of a letter grade sorted by male or female to determine if there was a significant gender difference in the final grades. Our objectives were to: 1) determine if the underrepresentation of women in some health-related jobs is due to discouragement of females to enter these professions or …

Comparison Of The Effect Of Caffeine Ingestion On Time To Exhaustion Between Endurance Trained And Untrained Men, Steven Porterfield, Jon Linderman, Lloyd L. Laubach, Corinne M. Daprano

Health and Sport Science Faculty Publications

This study compared the ergogenic effects of caffeine on men who were endurance trained to those who were untrained. The study was a double-blind, placebo-controlled crossover experimental design. Ten endurance trained men (mean age 24.4 ± 2.0 yrs, weight 79.4 ± 8.5 kg, predicted VO2 max 46.3 ± 1.8 mL·kg-1·min-1) and 10 untrained men (mean age 22.8 ± 1.9 yrs, weight 88.9 ± 9.9 kg, predicted VO2 max 37.6 ± 2.7 mL·kg-1·min-1) completed two cycle ergometer trials to exhaustion at 80% of their predicted workload max 30 min after ingesting either 5 mg·kg-1 of body weight of caffeine or a …

Pursuing Wellness: Achieving Fall Reduction Through Staff And Patient Partnership, Lisa A. Lacy, Nicole J. Urban-Miller Rn, Bsn, Denise Bodish Bsn, Rnbc, Jane Halpin Rnc, Pcc, Colleen S. Green, Kathryn P. Mercadante Rn

Patient Care Services / Nursing

No abstract provided.

Prevention Of Type 2 Diabetes In Urban American Indian/Alaskan Native Communities: The Life In Balance Pilot Study, Daniel C. Benyshek, Michelle Chino, Carolee Dodge-Francis, Toricellas O. Begay, Hongbin Jin, Celeste Giordano

Environmental & Global Health Faculty Research

Objective: The Life in BALANCE (LIB) study is a pilot translational study modeling the Diabetes Prevention Program (DPP) intensive lifestyle coaching intervention among an underserved, high-risk population: American Indians/Alaska Natives (AI/ANs) living in a large urban setting (Las Vegas, Nevada). Research Design and Methods: A total of 22 overweight/obese AI/ANs (age, 39.6 ± 10.4 years; BMI, 34.1 ± 6.3 kg/m2) at increased risk for developing type 2 diabetes (HbA1c > 5.4 (36 mmol/mol) < 6.4 percent (46 mmol/mol) participated in the program between April and December, 2011. Study participants completed a 16 week intensive lifestyle coaching intervention. In addition to obtaining qualitative data regarding opportunities and challenges of applying the lifestyle intervention for AI/AN participants in an urban setting, clinical data, including BMI, waist circumference, blood pres- sure, fasting blood glucose, and blood lipids (HDL, LDL and Triglycerides), were collected. Results: Only 12 of the 22 participants remained in the LIB program at the final post-program follow-up. Participants demonstrated significant decreased waist circumference and elevated HDL cholesterol. Triglycerides manifested the highest percentage change without statistical significance. No significant change was ob- served in blood pressure or fasting blood glucose. Conclusions: LIB participants’ improvements in BMI, waist circumference, HDL cholesterol and triglycerides suggests type 2 diabetes prevention programs aimed at urban AI/ANs show significant potential for reducing the risk of developing type 2 diabetes among this underserved and high risk community. Qualitative data suggest the main challenge for type 2 diabetes prevention specific to this population is a need for improved community outreach strategies.

Research: South Dakota State University, Fall 2013, Chrisite Delfanian, Eric Landwehr

State of Discovery South Dakota State University's Research Magazine

CONTENTS:

Breaking Waves: Study of breaking waves relevant for lake shorelines [Page] 2
Poetic imagery rooted in research [Page] 3
Virus genome may hold key to better PRRS vaccine [Page] 4
Consumer survey examines savings behaviors, goals [Page] 4
Soybean meal may decrease fish production costs [Page] 5
Alternative fuel sources add value to SD products [Page] 6
International collaboration helps meet global demand for wheat [Page] 7
Commercialization requires big thinking [Page] 9
Young scientist develops software for cancer detection, image transmission [Page] 10
Nursing research to improve rural health care [Page] 11
New vaccine-delivery system targets influenza, cancer …

Drug Firms, The Codification Of Diagnostic Categories, And Bias In Clinical Guidelines, Lisa Cosgrove, Emily E. Wheeler

Counseling, School Psychology & Sport Faculty Publication Series

The profession of medicine is predicated upon an ethical mandate: first do no harm. However, critics charge that the medical profession’s culture and its public health mission are being undermined by the pharmaceutical industry’s wide-ranging influence. In this article, we analyze how drug firms influence psychiatric taxonomy and treatment guidelines such that these resources may serve commercial rather than public health interests. Moving beyond a conflict-of-interest model, we use the conceptual and normative framework of institutional corruption to examine how organized psychiatry’s dependence on drug firms has distorted science. We suggest that academic-industry relationships have led to the corruption of …

Premedical Programs Newsletter, October 2013, University Of Dayton

Pre-Health Resource Center Campus Communications

Newsletter for students, staff, and faculty in the premedical and predental programs.

Intimate Partner Violence During Pregnancy: Victim Or Perpetrator? Does It Make A Difference?, Yuliya Shneyderman, Michele Kiely

Publications and Research

Objectives: To differentiate between forms of intimate partner violence (IPV)(victim only, perpetrator only, or participating in reciprocal violence) and examine risk profiles and pregnancy outcomes.

Design: Prospective

Setting: Washington, DC, July 2001 to October 2003

Sample: 1044 high-risk African-American pregnant women who participated in a randomized controlled trial to address IPV, depression, smoking, and environmental tobacco smoke exposure.

Methods: Multivariable linear and logistic regression

Main outcome measures: Low and very low birth weight, preterm and very preterm birth

Results: 5% of women were victims only, 12% were perpetrators only, 27% participated in reciprocal violence, and 55% reported no IPV. …

Sequential Screening For Psychosocial And Behavioural Risk During Pregnancy In A Population Of Urban African Americans, Michele Kiely, Marie G. Gantz, M. Nabil El-Khorazaty, Ayman El-Mohandes

Publications and Research

Objective: Screening for psychosocial and behavioral risks, such as depression, intimate partner violence and smoking, during pregnancy is considered state-of-the-art in prenatal care (PNC). This prospective longitudinal analysis examines the added benefit of repeated screening over a one-time screen in identifying such risks during pregnancy.

Design: Data were collected as part of a randomized controlled trial to address intimate partner violence (IPV), depression, smoking and environmental tobacco smoke exposure (ETSE) in African-Americans women.

Setting: PNC sites in the District of Columbia serving mainly minority women

Population: 1044 African-American pregnant women in the District of Columbia

Methods: Mothers were classified by …

Resveratrol Induced Apoptosis In A Human Adenosquamous Carcinoma Cell Line (Cal-27 Cells), Saquib A. Siddiqi

PCOM Biomedical Studies Student Scholarship

Radiotherapy and surgery are the two principal modalities in the treatment of head and neck cancers, and both therapies can result in severe adverse effects and ultimately lower the quality of life. It is of paramount importance to develop reagents that target the cancer cell specifically without affecting the normal non-cancer cells. Using the tongue cancer cell line Cal 27 as a model system, we dissected the molecular mechanism of the resveratrol-induced cancer cell apoptosis. After demonstrating that resveratrol induces the cancer cell apoptosis in a dose- and time-dependent manner, a systemic apoptosis protein array was conducted to identify the …

The Role Of Rehabilitation Following Autologous Chondrocyte Implantation: A Retrospective Chart Review, Jenny L. Toonstra, Jennifer Sebert Howard, Timothy L. Uhl, Robert A. English, Carl G. Mattacola

Physical Therapy Faculty Publications

PURPOSE/BACKGROUND: Clinical outcomes following autologous chondrocyte implantation (ACI) are influenced by multiple factors, including patient demographics, lesion characteristics, quality of the surgical repair, and post-operative rehabilitation. However, it is currently unknown what specific characteristics of rehabilitation have the greatest influence on clinical outcomes following ACI. The purpose of this study was to conduct a retrospective chart review of patients undergoing ACI with the intent to describe this patient population's demographics, clinical outcomes, and rehabilitation practices. This study aimed to assess the consistency of the documentation process relative to post-operative rehabilitation in order to provide information and guide initiatives for improving …

Cryotherapy Following Visual Inspection With Acetic Acid And Lugol's Iodine (Via/Vili) In Khwisero, Western Kenya: Lesson From The Field Affecting Policy And Practice, Sammy Ngichabe, Patricia Muthaura, Christine W. Murungi, J. Muyoka, Elkanah Omenge, L Muchiri

Obstetrics and Gynaecology, East Africa

Background: Cervical cancer can be prevented and mortality/morbidity reduced by early detection and referral. Developing countries are likely to benefit from more cost effective methods of screening and treatment. Visual inspection with acetic acid and Lugol`s iodine (VIA/VILI) offers a see and treat solution thus an affordable and efficient way to identify pre-malignant lesions. Immediate treatment with cryotherapy can be offered if pre-malignant lesions are found on visual inspection. Cryotherapy is a simple procedure that is curative for dysplasia; it is likely to benefit cervical dysplasia cases picked early in resource poor settings, however there are several factors that …

Physician Care: Best Practices In Patient-Centered Care, Elisabeth Kunkel, Md, Susan Krekun, Md, Jennifer Jasmine Arfaa, Phd, Mhsa, Eleanor Gates, Msn, Rn, Mary Ann Mcginley, Phd, Rn, Leo Katz, Md, Andrew Miller, Md, Mph, Cynthia Line, Phd, Teresa Heavens

Department of Psychiatry and Human Behavior Faculty Papers

APPROACH TO PROBLEM SOLVING

During fiscal year 2013, TJUH targeted “communication with physicians” for improvement as this HCAHPS domain was at 76% (trended July to September, 2010). The primary challenge to improving this score was that of physician investment and buy-in.

Engagement of physicians was achieved through the creation of the Physician CARE (Communication, Attention, Respect, and Expertise) task force. Identified as essential for success were:

·Investment by physician specialty departments/stakeholders

·Strong support by hospital leadership and the engagement of physician stake holders and physician leaders

·Increasing physician understanding of and access to patient experience scores

Incidence And Management Of Rhinosinusitis After Complex Orbitofacial Reconstruction., William Parkes, Gurston G. Nyquist, Christopher Rizzi, Sarah Zhang, James J. Evans, Ryan N. Heffelfinger, Marc Rosen, Joseph Curry

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

OBJECTIVE: To examine the sinus-related sequelae of free flap reconstruction for complex orbitofacial defects.

STUDY DESIGN: Retrospective chart review METHODS: Demographic, clinical, and radiographic data on a series of 55 patients who had undergone free tissue transfer for orbitofacial reconstruction was retrospectively reviewed. Follow-up of ≥ 3 months was available for 49 patients. Outcome measures studied included clinical or radiographic evidence of sinusitis and the need for sinus surgery.

RESULTS: The most commonly involved sinuses were the ethmoid (n=40) and maxillary (n=38) sinuses, and the anterolateral thigh was the most common flap used (n=41). Clinical and/or radiographic sinusitis was evident …

The Drosophila Eve Insulator Homie Promotes Eve Expression And Protects The Adjacent Gene From Repression By Polycomb Spreading., Miki Fujioka, Guizhi Sun, James B Jaynes

Department of Biochemistry and Molecular Biology Faculty Papers

Insulators can block the action of enhancers on promoters and the spreading of repressive chromatin, as well as facilitating specific enhancer-promoter interactions. However, recent studies have called into question whether the activities ascribed to insulators in model transgene assays actually reflect their functions in the genome. The Drosophila even skipped (eve) gene is a Polycomb (Pc) domain with a Pc-group response element (PRE) at one end, flanked by an insulator, an arrangement also seen in other genes. Here, we show that this insulator has three major functions. It blocks the spreading of the eve Pc domain, preventing repression of the …