Medicine and Health Sciences Commons^™

An Examination Of Ethnic Differences In Body Image Among Male College Students, Ricardo Rios

McNair Poster Presentations

Body Image and Culture

• Limited research examines body image in males and ethnic minorities.
• Appearance ideals are often defined by an individual's membership in a given culture.
• Western cultures puts considerable emphasis on physical appearance.
• There is variability across cultures with regards to male body image.

Body Image and Media

• Western Media negatively influences body image.
• Media's portrayal of male bodies have become more muscular over the years.
• Contemporary male ideal body is highly muscular, lean, tall, with broad shoulders, a brawny chest, and a slim waist.

Body Dissatisfaction

• Negative body Image: being dissatisfied with one's appearance
• Has been linked …

A Pooled Analysis Of The Resistance Patterns Of Escherichia Coli Strains Isolated From Urine Cultures In Turkey: A Comparison Of The Periods 1997-2001 And 2002-2007, Meltem Işikgöz Taşbakan, Hüsnü Pullukçu, Oğuz Reşat Si̇pahi̇, Tansu Yamazhan, Bi̇lgi̇n Arda, Sercan Ulusoy

Turkish Journal of Medical Sciences

To compare the resistance patterns of Escherichia coli strains reported to be isolated from urine cultures in published medical literature from Turkey in 1997-2001 and 2002-September 2007. Materials and methods: To find the published series, 3 national databases (Ulakbim Turkish Medical Literature database, http://www.turkishmedline.com, http://medline.pleksus.com.tr), and 2 international databases (Pubmed and Science Citation Index (SCI)) were searched. Results: Data for 25,577 E. coli strains were obtained from 53 articles (28 articles from 1997-2001, 25 from 2002-2007). Of these strains 18,106 were isolated from outpatients, whereas 7471 were from inpatients. When the strains isolated from outpatients were evaluated, there was a …

Can Obstructive Apnea And Hypopnea During Sleep Be Differentiated By Using Electroencephalographic Frequency Bands? Statistical Analysis Of Receiver-Operator Curve Characteristics, Erdem Uçar, Necdet Süt, Tevfi̇k Gülyaşar, İlhan Umut, Levent Öztürk

Turkish Journal of Medical Sciences

To investigate whether electroencephalographic (EEG) frequency bands are applicable in distinguishing abnormal respiratory events such as obstructive apnea and hypopnea in patients with sleep apnea. Materials and methods: The polysomnographic recordings of 20 patients were examined retrospectively. EEG record segments were taken from C4-A1 and C3-A2 channels and were analyzed with software that uses digital signal processing methods, developed by the study team. Percentage values of delta, theta, alpha, and beta frequency bands were evaluated through discriminant and receiver-operator curve (ROC) analysis to distinguish between apneas and hypopneas. Results: For the C4-A1 channel, delta (%) provided the highest discriminative value …

An Efficient Method For Stable Transfection Of Mouse Myogenic C2c12 Cell Line Using A Nonviral Transfection Approach, Mehmet Deni̇z Akyüz, Burcu Hayta, Pervi̇n Ruki̇ye Di̇nçer

Turkish Journal of Medical Sciences

To describe in detail the use of the T-REx^{TM} System (a tetracycline-regulated mammalian expression system; Invitrogen) for rapid, easy, and effective generation of stable C2C12 cell clones. Tetracycline-inducible stable cell lines are useful tools to study the function of various genes in different types of mammalian cells. However, the generation of stable cell lines is a time-consuming, technically difficult, and expensive process. Materials and methods: Generation of a stable C2C12 cell line was performed by stable transfection of the cells with the pcDNA6/TR plasmid vector, which contains the tetracycline repressor and the blasticidin drug resistance genes. The establishment of the …

The Role Of Anemia And Vitamin D Levels In Acute And Chronic Telogen Effluvium, Ayşe Serap Karadağ, Derun Taner Ertuğrul, Emre Tutal, Kadi̇r Okhan Akin

Turkish Journal of Medical Sciences

Telogen effluvium (TE) is an abnormality of hair cycling. Vitamin D promotes hair follicle differentiation. The importance of vitamin D in hair growth is evident in patients with hereditary vitamin D receptor deficiency. The role of vitamin D in the pathogenesis of TE has not been investigated before. We investigated the role of vitamin D, ferritin, and zinc in the pathogenesis of TE. Materials and methods: We measured serum hemoglobin, ferritin, zinc, calcium, phosphate, parathormone, magnesium, 25 and 1,25-hydroxyvitamin D3, and bone alkaline phosphatase and thyroid stimulating hormone levels in 63 female patients and 50 control subjects. Twenty-nine of the …

Distribution Of Congenital Heart Disease In Turkey*, Serdar Kula, Ayhan Çevi̇k, Fatma Rana Olguntürk, Fatma Sedef Tunaoğlu, Ayşe Deni̇z Oğuz, Mustafa Necmi̇ İlhan

Turkish Journal of Medical Sciences

To describe the epidemiology and geographical distribution of congenital heart disease. A retrospective population-based study was conducted using data collected in a large tertiary care hospital in Turkey. Materials and methods: The medical records of 1300 patients with congenital heart disease admitted to the Gazi University Department of Pediatric Cardiology for catheter angiography from 1997-2007 were reviewed. The patients were divided into 7 groups according to geographical distribution, and each group was further divided into 2 groups, for simple (group 1) and complex (group 2) congenital heart disease. Results: Among the 1300 cases, there was no difference between the regions …

Assessment Of The Left Atrial Longitudinal Myocardial Function By Assessment Of The Left Atrial Longitudinal Myocardial Function By The Strain And Strain Rate Echocardiography In Patients With Rheumatic Mitral Stenosis*, Enbi̇ya Aksakal, Serdar Sevi̇mli̇, Hanefi̇ Yekta Gürlertop, Mehmet Ali̇ Elbey, Muhammed Hakan Taş, Fuat Gündoğdu, Mustafa Kemal Erol, Şule Karakelleoğlu

Turkish Journal of Medical Sciences

To evaluate the regional left atrial (LA) myocardial functions and time to peak deformations by the longitudinal strain (S) and strain rate (Sr) echocardiography in isolated mitral stenosis (MS) patients for 3 LA periods (contractile, reservoir, and conduit periods). Materials and methods: Included in the study were 30 MS patients and 30 healthy controls. Longitudinal peak S and Sr indices, time to peak S and time to peak Sr, and systolic and diastolic velocities were measured from the color Doppler myocardial imaging data, for each LA period. Results: For all 3 periods, all of the segment S values and most …

Physicians' Attitudes Toward Clinical Ethics Consultation: A Research Study From Turkey, Funda Gülay Kadioğlu, Rana Can, Selda Okuyaz, Si̇bel Öner Yalçin, Nuri̇ Seli̇m Kadioğlu

Turkish Journal of Medical Sciences

To identify the reasons why physicians request or do not request ethics consultation and to determine the priority of ethical issues for those demanding consultation. Materials and methods: This survey was conducted using a self-administered questionnaire, and 270 clinicians (surgeons and internists) from 3 different medical school hospitals were included. The questionnaire consisted of Likert-type statements related to the reasons for requesting or not requesting ethics consultation and a ranking list of ethical dilemmas according to the physicians' priorities. Results: Of all clinicians, 40.4% were employed in surgical departments and 59.6% in internal medicine departments. Most of the physicians (90%) …

Lead Identification Of Β-Lactam And Related Imine Inhibitors Of The Molecular Caperone Heat Shock Protein 90, Niamh O'Boyle, Andrew Js Knox, Trevor P. Price, D. Clive Williams, Daniela M. Zisterer, David G. Lloyd, Mary J. Meegan

Articles

Heat shock protein 90 is an emerging target for oncology therapeutics. Inhibitors of this molecular chaperone, which is responsible for the maintenance of a number of oncogenic proteins, have shown promise in clinical trials and represent a new and exciting area in the treatment of cancer. Heat shock protein 90 inhibitors have huge structural diversity, and here we present the identification of inhibitors based on β-lactam and imine templates. β-Lactam 5 and imines 12 and 18 exhibit binding to heat shock protein 90-α with IC₅₀ values of 5.6 μM, 14.5 μM and 22.1 μM respectively. The binding affinity displayed …

Perspectives Of Women In Leadership Roles: Working Through The Change, Philippa Gavranich

Theses

The majority of women will experience perimenopausal symptoms (Hickey, Davis & Sturdee, 2005; MacLennan, 2009) with an estimated 20% of those experiencing severe symptoms (Hickey et al., 2005). Many of these symptoms have the potential to directly or indirectly affect work performance including hot flushes and night sweats which are experienced by 85% of perimenopausal women (Baldo, Schneider, & Slyter, 2003). Symptoms may begin several years before the cessation of menstruation and may last well into old age (MacLennan, 2009).

This research sought to explore the perceived impact of perimenopausal symptoms on women in leadership roles: how they managed symptoms; …

Promoting The Translational Relationship Between Public Health Practice And Research, Julie Gleason-Comstock

Michigan Journal of Public Health

No abstract provided.

Norovirus Epidemiology And Duration Of Shedding In Michigan, 2007-2008, Nodira A. Abdujamilova, David Dixon, Laura Mosher, Patricia Somsel, Anthony Muyombwe, Patricia A. Clark, Jeffrey Massey, Brenda Brennan, Paul C. Bartlett

Michigan Journal of Public Health

Background: In the United States, an estimated 23 million cases of norovirus (NoV) are reported each year, and although mortality is low, the morbidity and economic impact are substantial. Methods: RT-PCR and sequencing were used for identification of NoV genotypes obtained from outbreak and sporadic cases. RT Quant PCR was used to determine the viral load in fecal specimens. In order to rule out bacterial infection as the cause for acute gastroenteritis (AGE), bacterial culture for Salmonella, E.coli O157, Shigella, Campylobacter and Clostridium difficile was performed by standard laboratory procedures. The duration of NV shedding was investigated with longitudinal sampling …

Could A Mid-Level Dental Provider Increase Access To Oral Health Care In Michigan?, H. Luke Shaefer, Renee Tetrick, Elizabeth Phillips

Michigan Journal of Public Health

According to a 2000 Surgeon General’s report, the United States faces an epidemic of unmet oral health needs, the result of both the high cost of care and geographic maldistribution of providers. This article assesses the extent of this unmet health care needs in Michigan, and examines one possible solution: the introduction of a mid-level dental provider (MDP) who could provide preventive and basic restorative care, under the supervision of a Michigan dentist. MDPs in various forms currently practice in over 50 countries including Canada and the U.K. The evidence suggests that a large and rigorous pilot of mid-level dental …

Public Health Partnerships In Action: A Selection Of Session Presentations From The 2011 Michigan Public Health Conference, Julie Gleason-Comstock, Teresa Wehrwein

Michigan Journal of Public Health

No abstract provided.

Public Health Action In Addressing The Michigan Medical Marihuana Law, Maurice S. Reizen, Amy A. Moore

Michigan Journal of Public Health

No abstract provided.

Optimization Strategies For Successful Ehr Adoption, Erin Faverty

Communication & Leadership Dissertations and Theses

The healthcare industry is experiencing a shift in care delivery and documentation as the nation moves toward electronic health record adoption (EHR). This project examines the benefits and hurdles to adoption faced within the industry and provides a detailed curriculum guide of strategies, approaches and materials for consultants assisting healthcare organizations in EHR implementation. The recommendations provided by this project are grounded in the theories of organizational culture as presented by Clifford Geertz (1977) and Michael Packanowsky (Griffin 2009, p. 252), as well as insights on the impacts of computer-mediated communication, as discussed by Joseph Walthers (Barrow, 2010). Materials presented …

Measuring A Community-Based Mental Health Organization’S Culture And Climate Scores Stability, David A. Patterson Silver Wolf (Adelv Unegv Waya) Phd, Eugene Maguin Phd, Catherine N. Dulmus Phd, Bruce C. Nisbet

Brown School Faculty Publications

This project builds on the work of Glisson et al., (2008) and the knowledge learned from community-based mental health organization’s internal structures (e.g., culture and climate), which possibly impede the implantation and adoption of new technologies. The Organizational Social Context (OSC) Model measurement system is guided by a model of social context that composes both organizational and individual level constructs, including individual and shared perceptions that are believed to mediate the impact of the organization on the individual. Although the OSC has been developed and validated over time, the literature does not provide guidance on test-retest reliability of the scale.

The Effect Of Female Education On Fertility And Infant Health: Evidence From School Entry Policies Using Exact Date Of Birth, Justin Mccrary, Heather Royer

Faculty Scholarship

This paper uses age-at-school-entry policies to identify the effect of female education on fertility and infant health. We focus on sharp contrasts in schooling, fertility, and infant health between women born just before and after the school entry date. School entry policies affect female education and the quality of a woman’s mate and have generally small, but possibly heterogeneous, effects on fertility and infant health. We argue that school entry policies manipulate primarily the education of young women at risk of dropping out of school.

Gabaergic Signaling To Adult-Generated Neurons In Hippocampus, Sean Markwardt

All ETDs from UAB

In the central nervous system of adult mammals, new neurons are produced throughout life in at least two regions, the subventricular zone and dentate gyrus of the hippocampus. New neurons in the SVZ migrate via the rostral migratory stream and eventually participate in adaptive olfactory processes. In the dentate gyrus, a variety of physiological functions for continued addition of neurons have been proposed, but its role in normal or pathological conditions remains largely unclear. Neurogenesis in the dentate gyrus consists of the stepwise process of generating fully functional granule cells (GCs) from adult neural stem cells. Regulation of neurogenesis can …

Role Of Calcium-Activated Potassium Channels In Glioblastoma Volume Regulation, Michael Bryan Mcferrin

All ETDs from UAB

The most common and most malignant gliomas are the Grade IV Glioblastoma Multiforme (GBM), characterized by a highly proliferative tumor mass and extremely invasive phenotype that allows for profuse dispersal of tumor cells throughout the brain. GBM cells must specifically regulate their cell volume to thrive within the edematous tumor mass and infiltrate throughout the tortuous extracellular spaces of the brain. These rapid and directed volume changes are governed by the controlled flux of potassium and chloride ions across the cell membrane, which move osmotically obliged water. The goal of this dissertation was to investigate the role of calcium-activated potassium …

Killer Immunoglobulin-Like Receptors And Human Leukocyte Polymorphisms In Hiv-1 Pathogenesis, Aimee Marie Merino

All ETDs from UAB

Human leukocyte antigen (HLA) molecules influence the adaptive and innate immune responses through interactions with cytotoxic T lymphocytes and natural killer cells (NK). HLA influence the activation state of NK through direct binding to killer immunoglobulin-like receptors (KIR) and presentation of HLA-derived peptides to NKG2 receptors. Activated NK can kill HIV-infected cells through direct cytolysis and release cytokines that influence other aspects of the immune system. Variations in KIR gene content and allelic variants have been associated with autoimmunity, transplantation success, and infectious diseases such as hepatitis C and HIV/AIDS. We investigated the impact of KIR genes and potential KIR-HLA …

Structural And Mechanistic Studies On Er Upr Sensor Perk And Mitochondrial Translocon Element Tim44, Wenjun Cui

All ETDs from UAB

The unfolded protein response is one mechanism utilized by endoplasmic reticulum (ER) to maintain the homeostasis between ER protein folding machinery and ER proteins. UPR is induced by three ER transmembrane sensors: IRE1, ATF6 and PERK. PKR-like ER kinase (PERK) can sense the ER stress signal through its luminal domain to activate its cytoplasmic kinase domain catalytic activity. PERK kinase domain belongs to the eIF2α family. Members in this family are activated after being autophosphorylated at their activation loops and then specifically phosphorylate eIF2α at its Ser51 position. Phosphorylation of eIF2α can shutdown the cytosol protein translation from the initiation …

Effects Of Estrogen On Hippocampal Function In Young Adult And Aged Female Rats, Lindsey Celeste Vedder

All ETDs from UAB

In rodents, the ovarian estrogen 17b-estradiol (E2) is a potent modulator of hippocampal function and the hippocampus is critical for many types of learning and memory. Specifically, E2 increase the magnitude of long-term potentiation (LTP) at CA3-CA1 synapses, the density of dendritic spines in CA1 pyramidal cells and current mediated by NR2B-containing NMDA receptors. The E2-induced increase in LTP further requires NR2B-containing NMDARs. While considered a cellular correlate of learning and memory, enhanced LTP does not always predict enhanced learning. The first goal of this dissertation was to investigate the relationship between E2-enhanced LTP and learning and memory in young …

Role Of Nr4a3 Nuclear Receptor In Physiological Regulation Of Metabolism, Grace R. Walton

All ETDs from UAB

Nuclear receptor NR4A3 (NOR-1, MINOR) mediates transcriptional responses to ß-adrenergic signaling, is increased in insulin sensitive mice and humans, and enhances insulin-stimulated glucose transport in cultured adipocytes and myocytes. We therefore sought to determine the role of NR4A3 in in vivo adipose tissue and skeletal muscle physiology. Following adipose-specific NR4A3 over-expression in mice, we observed reduced circulating epinephrine due to enhanced catabolism of catecholamines in adipose tissue. Furthermore, this reduction in circulating epinephrine produced broad physiological consequences, including poor glucose tolerance, reduced insulin sensitivity, dyslipidemia, poor cardiac function, and behavioral alterations. In skeletal muscle, we show that NR4A3 protein associates …

Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram

All ETDs from UAB

Successful treatment of breast cancer directly correlates with tumor stage and grade at diagnosis. Early diagnosis leads to a five-year relative survival rate of 96.8% as opposed to only a 22.5% five-year survival rate when diagnosed at late stage. Cancer-specific mechanisms need to be extended to enable cancer detection in an individual patient, in particular, the metastatic burden that currently cannot be assessed by conventional imaging. This approach for cancer detection would remove the biases of patient characteristics, permit immediate diagnostic feedback, improve sensitivity for early detection of small metastatic lesions, and be cost effective. Toward this goal, the cancer-specific …

Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White

All ETDs from UAB

The virus Eastern Equine Encephalitis virus (EEEV) is a highly pathogenic arthropod-borne virus (arbovirus) present in the US. The virus is listed as a reportable illness to the Centers of Disease Control and Prevention (CDC) and is also listed as a select agent by Human Health and Services (HHS). Studies on EEEV starting back in the 1930's have determined many important facets of the ecology, transmission and evolution of the virus. It is understood that in many endemic foci, the mosquito Culiseta melanura is the primary enzootic vector of the virus. EEEV is thus maintained in an enzootic cycle between …

Conceptualization Of Cervical Cancer And Screening Experiences Among Zambian Women Attending A Cervical Screening Program, Heather Leah White

All ETDs from UAB

Invasive cervical cancer (ICC) is the second most commonly diagnosed malignancy worldwide, and approximately 85% of the disease burden occurs in underdeveloped countries. In 2006, the Zambian government launched a cervical screening program within primary health clinics using visual inspection with acetic acid (VIA) coupled with immediate treatment via cryotherapy. The objective of this dissertation was to determine whether the VIA screening program is responsive to the needs and concerns of Zambian women in an effort to improve screening uptake, and for human immunodeficiency virus (HIV) positive women who are potentially subject to increased ICC screening and treatment, increase long-term …

Functional Interplay Between Trans Factors And Cis-Elements That Govern Il17a&F Transcription, Sarah Kern Whitley

All ETDs from UAB

Protective immunity against a variety of infections depends on the amplification and differentiation of naïve antigen-specific CD4 T cells. T helper 17 (Th17) cells are important for defending mucosal barriers from invading extracellular bacterial pathogens. This effector CD4 lineage is characterized by production of the cytokines IL-17A, IL-17F, IL-21, and IL-22, which elicit influx of inflammatory cells to promote pathogen clearance. The cytokines IL-6 and TGF&beta are the principal factors that initiate Th17 lineage development, and the STAT3-inducing cytokines IL-21 and IL-23 assist and/or maintain the Th17 developmental program. Recently, an additional cytokine has been demonstrated to encourage Th17 differentiation: …

Pick It Up, Put It Down: A Grounded Theory Study Of How Low Income African American Patients In The Deep South Start Smoking And Quit Smoking, Jessica Hillman Williams

All ETDs from UAB

The purpose of this qualitative was to use data extracted from the narrative stories of African American patients to generate a grounded theory to explain the process and act of initiating and of quitting smoking among low income African American patients in the Deep South. This is important since African Americans are more likely to suffer from smoking-related illnesses, which are the leading cause of death among African Americans. Data were analyzed from interviews conducted in 2005 as part of the Stories Project and supplementary interviews conducted in 2011. Convenience sampling strategies guided participant recruitment for primary interviews and theoretical …

Tear Component Interference In Bead-Based Biomarker Assays Using Magnetic Beads, Larezia Denise Williams

All ETDs from UAB

Cytokines in tears can be biomarkers for ocular inflammation in dry eye subjects. Multiplex bead-based assays measure the concentration of multiple cytokines in a single tear sample. Bio-Rad® polystyrene bead-based assay kits have provided acceptable results for tear samples in this lab. Recently, Bio-Rad decided to replace polystyrene beads with magnetic beads. In earlier experiments in this laboratory, magnetic bead-based as-says did not produce results equivalent to polystyrene bead-based assays. The purpose of this investigation was to modify the magnetic bead-based tear cytokine assay to produce equivalent results to those obtained with the polystyrene bead-based assay. The modifications included running …