Medicine and Health Sciences Commons^™

Does Use Of A Cell Phone Affect Cognition?, Kharma J. Lundy

PCOM Biomedical Studies Student Scholarship

This research examined the effects that a cell phone distraction had on subjects completing a maze task. Twenty-four subjects participated in the study (12 Younger subjects and 12 Older subjects; 14 females and 10 males). Subjects completed an identical maze task during each of three sessions. During the first session, subjects completed the maze task without the distraction of cell phone use. The second session involved completion of the maze task while listening to a transcript read over a cell phone. The third session involved completion of the maze task while participating in a cell phone conversation. Subjects’ performances were …

Alzheimer's Disease Association With Chlamydia Pneumoniae, Andrew Short

PCOM Biomedical Studies Student Scholarship

Exogenous bacteria, such as Chlamydia pneumoniae, may be a cause of inflammation that contributes to the progression of Alzheimer's disease (AD). Inflammation has been previously established as a contributor to AD progression. Balin et al. first reported C. pneumoniae in the brains of post-mortem late onset AD patients. PCR analysis showed that 17/19 AD patients were positive for the organism in areas of the brain with typical AD-related neuropathology while 18/19 control patients were PCR-negative. Gerard et al. determined, using real-time PCR, that C. pneumoniae-infected cells colocalize with both neuritic senile plaques and neurofibrillary tangles, the defining pathologies of AD. …

An Investigation Of The Subtype Diversity Of Clinical Isolates Of Irish Clostridium Difficile Ribotypes 027 And 078 By Repetitive-Extragenic Palindromic Pcr, Denise Drudy, K. Solomon, S. Murray, L. Scott, S. Mcdermott,, A. Martin, C. O’Donoghue, M. Skally, K. Burns, L. Fenelon, F. Fitzpatrick,, L. Kyne, S. Fanning

Articles

A repetitive-extragenic palindromic PCR (rep-PCR) subtyping method (DiversiLab) in conjunction with ribotyping, toxinotyping and antimicrobial-susceptibility testing was used to detect subtypes within Clostridium difficile ribotypes 027 and 078. Clinical isolates of ribotypes 027 (toxinotype III) (n530) and 078 (toxinotype V) (n523) were provided by health-care facilities across the Republic of Ireland over 2 months in 2006 and 1 month in 2009. Ribotype 027 isolates were significantly more related to each other (9 different subtype profiles) when compared to ribotype 078 isolates (14 different profiles) (P50.001; cut-off .90 % similarity). Almost half of ribotype 078 isolates (45.5 %) showed no relationship …

Review Of: The Therapeutic Electrophysical Agents: Evidence Behind Practice, 2nd Edition, Cindy Laporte

Internet Journal of Allied Health Sciences and Practice

No abstract provided.

Cardiac Output Is Not Related To The Slowed O2 Uptake Kinetics In Type 2 Diabetes, Oscar Mac Ananey, J Malone, S Warmington, D O'Shea, S Green, M Egana

Articles

Abstract

PURPOSE:

This study aimed to investigate whether cardiac output (CO) responses were related to VO2 kinetics during cycling in type 2 diabetes.

METHODS:

A total of 9 middle-aged women with uncomplicated type 2 diabetes, 9 nondiabetic overweight women, and 11 nondiabetic lean women were recruited. Initially, the ventilatory threshold (VT) and peak VO2 were determined during a maximal graded test. Then, on two separate days, subjects completed three 7-min bouts of constant-load cycling at each of three intensities: 50% VT, 80% VT, and midpoint between VT and peak VO2 (50% Δ). CO (inert gas rebreathing) was recorded at 30 …

Effect Of Type 2 Diabetes On The Dynamic Response Characteristics Of Leg Vascular Conductance During Exercise, Oscar Mac Ananey, H Reilly, D O'Shea, M Egana, S Green

Articles

Abstract

In this study we tested the hypothesis that type 2 diabetes impairs the dynamic response of leg vascular conductance (LVC) during exercise. LVC (leg blood flow/mean arterial pressure) responses were studied during intermittent contractions of the calf muscle in subjects with type 2 diabetes (n = 9), heavy controls (n = 10) and lean controls (n = 8) using a biexponential function and an estimate of the mean response time (MRT). The time constant of the second phase of LVC was significantly greater in type 2 diabetes (66.4 ± 29.2 s) than the heavy (22.2 ± 13.4 s) and …

Arbovirus Phenotype Alters Transmission Potential, Rebecca C. Christofferson

LSU Doctoral Dissertations

Extrinsic and environmental factors are known to affect the transmission of arthropod-borne viruses (arboviruses), including variations in the arthropod vector populations. Differences among these factors have been associated with differential transmission and are sometimes used to control the spread of an arbovirus through a vertebrate population in an effort to prevent or disrupt an outbreak. However, diversity in intrinsic viral populations, such as genetic and phenotypic variability, is not often accounted for when considering alterations in transmission. Presented in this dissertation are four experimental studies that explore the contribution of viral intrinsic factors, especially phenotypic variability, to the transmission potential …

Culturally Competent Care In Parkinson's Disease, Melinda Hermanns

Nursing Faculty Publications and Presentations

Findings from a qualitative ethnographic study that examined the experiences of a group of persons with Parkinson disease are presented in this article. Culturally competent care for persons who share a common illness, such as Parkinson disease, is facilitated when the findings are incorporated into the Clinically Relevant Continuum Model. Use of this model allows providers to evaluate and use appropriate published evidence in addition to provider expertise and patient preferences and values.

Understanding The Decision-Making Process For Health Promotion Programming At Small To Midsized Businesses, M. Courtney Hughes, Donald L. Patrick, Peggy A. Hannon, Jeffrey R. Harris, Donetta L. Ghosh

Faculty Articles, Papers, and Other Scholarship

This study explores the decision-making process for implementing and continuing health promotion programs at small to midsized businesses to inform health promotion practitioners and researchers as they market their services to these businesses. Qualitative interviews are conducted with 24 employers located in the Pacific Northwest ranging in size from 75 to 800 employees, with the majority having between 100 and 200 employees. Small to midsized employers depend most on company success-related factors rather than on humanitarian motives when deciding whether to adopt workplace health promotion programs. They rely heavily on health insurers for health promotion and desire more information about …

Promoting Tobacco Cessation Via The Workplace: Opportunities For Improvement, M. Courtney Hughes, Emily M. Yette, Peggy A. Hannon, Jeffrey R. Harris, Nguyet M. Tran, Terry R. Reid

Faculty Articles, Papers, and Other Scholarship

Introduction: Little research exists on the prevalence of evidence-based tobacco cessation practices in workplaces, employer promotion of state-sponsored quitlines and predictors of these practices.

Methods: Cross-sectional analysis of the 2008 Healthy Worksite Survey, a telephone survey administered to Washington employers with 50 or more employees (n¼693). The objectives were to describe workplaces’ implementation of evidence-based tobacco cessation practices and identify key predictors of implementation in order to highlight opportunities for interventions.

Results: Among these employers, 38.6% promoted quitting tobacco, and 33.8% offered insurance coverage for cessation medications and counselling, 27.5% referred no-smoking violators to cessation services, and 5.7% included the …

Cumulative Clinical Experience From Over A Decade Of Use Of Levofloxacin In Community Acquired Pneumonia; Critical Appraisal And Role In Therapy, Ayman M. Noreddin, Walid F. Elkhatib, Kenji M. Cunnion, George G. Zhanel

Pharmacy Faculty Articles and Research

Levofloxacin is the synthetic L-isomer of the racemic fluoroquinolone, ofloxacin. It interferes with critical processes in the bacterial cell such as DNA replication, transcription, repair, and recombination by inhibiting bacterial topoisomerases. Levofloxacin has broad spectrum activity against several causative bacterial pathogens of community-acquired pneumonia (CAP). Oral levofloxacin is rapidly absorbed and is bioequivalent to the intravenous formulation such that patients can be conveniently transitioned between these formulations when moving from the inpatient to the outpatient setting. Furthermore, levofloxacin demonstrates excellent safety, and has good tissue penetration maintaining adequate concentrations at the site of infection. The efficacy and tolerability of …

Efficacious And Safe Tissue-Selective Controlled Gene Therapy Approaches For The Cornea, Rajiv R. Mohan, Sunilima Sinha, Ashish Tandon, Rangan Gupta, Jonathan C. K. Tovey, Ajay Sharma

Pharmacy Faculty Articles and Research

Untargeted and uncontrolled gene delivery is a major cause of gene therapy failure. This study aimed to define efficient and safe tissue-selective targeted gene therapy approaches for delivering genes into keratocytes of the cornea in vivo using a normal or diseased rabbit model. New Zealand White rabbits, adeno-associated virus serotype 5 (AAV5), and a minimally invasive hair-dryer based vector-delivery technique were used. Fifty microliters of AAV5 titer (6.561012 vg/ml) expressing green fluorescent protein gene (GFP) was topically applied onto normal or diseased (fibrotic or neovascularized) rabbit corneas for 2-minutes with a custom vector-delivery technique. Corneal fibrosis and neovascularization in rabbit …

A Comparison Of Pharmacist Travel-Health Specialists' Versus Primary Care Providers' Recommendations For Travel-Related Medications, Vaccinations, And Patient Compliance In A College Health Setting, Melissa J. Durham, Jeffery A. Goad, Lawrence S. Neinstein, Mimi Lou

Pharmacy Faculty Articles and Research

Background. Pretravel medication and vaccination recommendations and receipt were compared between primary care providers (PCPs) without special training and clinical pharmacists specializing in pretravel health.

Methods. A retrospective chart review of patients seen for pretravel health services in a pharmacist-run travel clinic (PTC) compared to PCPs at a University Student Health Center. Vaccine/medication recommendations were assessed for consistency with national/international guidelines. Medical/pharmacy records were queried to determine the receipt of medications/vaccinations.

Results. The PTC recommended antibiotics for travelers' diarrhea were given more often when indicated (96% vs 50%, p < 0.0001), and patients seen in the PTC received their medications more often (75% vs 63%, p = 0.04). PCPs prescribed more antibiotics for travelers' diarrhea that were inconsistent with guidelines (not ordered when indicated 49% vs 6%, p < 0.0001 and ordered when not indicated 21% vs 3%, p < 0.0001). The PTC prescribed antimalarials more often when indicated (98% vs 81%, p < 0.0001), while PCPs prescribed more antimalarials that were inconsistent with guidelines (not ordered when indicated 15% vs 1%, p < 0.0001 and ordered when not indicated 19% vs 2%, p < 0.0001). The PTC ordered more vaccines per patient when indicated (mean = 2.77 vs 2.31, p = 0.0012). PTC patients were more likely to receive vaccines when ordered (mean = 2.38 vs 1.95, p = 0.0039). PCPs recommended more vaccines per patient that were inconsistent with guidelines (not ordered when indicated: mean = 0.78 vs 0.12, p < 0.0001, ordered when not indicated: mean 0.18 vs 0.025, p < 0.0001).

Conclusions. A pharmacist-run pretravel health clinic can …

Attention-Deficit/Hyperactivity Disorder In Childhood Is Associated With Cognitive Test Profiles In The Geriatric Population But Not With Mild Cognitive Impairment Or Alzheimer's Disease, N. Ivanchak, Erin L. Abner, S. A. Carr, S. J. Freeman, A. Seybert, John Ranseen, Gregory A. Jicha

Sanders-Brown Center on Aging Faculty Publications

The frequency of ADHD in the aging population and its relationship to late-life cognitive decline has not been studied previously. To address this gap in our understanding, the Wender-Utah ADHD Rating scale (WURS) was administered to 310 geriatric subjects with cognitive status ranging from normal cognition to mild cognitive impairment to overt dementia. The frequency of WURS-positive ADHD in this sample was 4.4%. WURS scores were not related to cognitive diagnoses, but did show nonlinear associations with tasks requiring sustained attention. The frequency of ADHD appears stable across generations and does not appear to be associated with MCI or dementia …

The Lived Experience Of Discontinuing Hormonal Contraception Among Women In Rural Uganda, Joseph Mwizerwa, Locsin C. Rozzano

School of Nursing & Midwifery, East Africa

The purpose of the study was to describe the experience of discontinuing hormonal contraceptive use among women in rural Uganda. A significant number of women in Uganda discontinue hormonal contraception even though such method has been effective. Consequently, these women have unprotected sex, although not wanting to conceive. Narrative descriptions of the experiences by eight women were analyzed using content analysis. The findings describe the experience as Frustration and Helplessness, Living in Fear of Uncertainty, Ingenuity of using other methods of contraception, thus fostering the Accomplishments of being a wife, mother, and woman. Implications for nursing practice, research, and education …

Writing In Afghanistan, Ali-Reza Force

Quill & Scope

This paper represents an analysis of the way in which internet communication by a physician can impact a general audience.

Thoughts In A Disaster, Sean Kivlehan

Quill & Scope

This paper discusses Sean’s experiences in Haiti during his psychiatry clerkship.

A Polish Grandmother, Andrei Kreutzberg

Quill & Scope

A touching tribute to an amazing grandmother.

A Comparison Of Music As A Therapy Before And After The 20th Century In America, Chu-En Lin

Quill & Scope

This piece provides a historical overview of the use of music as a therapy in the Unites States, with an emphasis on the changes that have occurred over the past century.

Attitudes In Psychiatry In Bangalore, India, Akshay Lohitsa

Quill & Scope

An analysis of an international rotation in Bangalore, India where an American medical student was able to compare and contrast attitudes towards psychiatry and mental illness. Many third world countries boast cure rates comparable or better than the U.S. for schizophrenia and other psychiatric diseases, and it remains unclear why this would be. One possible reason of why this trend is occur-ring is provided.

Five Years And Counting, Mary B. O'Donnell

Quill & Scope

This paper highlights the vital role of La Casita de la Salud, New York Medical College’s student-run health clinic in East Harlem, as a resource to both the community and medical students.

An Interview With Doctor Daniel Peters, Jin Packard

Quill & Scope

An up, close and personal interview with Dr. Daniel Peters, retired surgeon, and the current Assis-tant Professor of Cell Biology and Gross Anatomy at NYMC with appointments in both the Medical School and the School of Health Sciences and Practices.

Private Interest, Ethics, And Sincere Medical Practice, Yousuf Sayeed

Quill & Scope

Healthcare providers are held to high standards in society. They are venerated as saintly figures that always mean well, working solely for the benefit of their patients. Upon closer observation, it seems that this is not always the case. With the juxtaposing relationship between private interest and genu-ine healthcare, patients are beginning to realize that some healthcare providers are more concerned with generating profit rather than treating their patients. Through examining personal experiences, documented studies, and enlightening cases of unethical medical practice, it is evident that work must be done to restore the trust between patients and their healthcare provider.

Medical Science And The Serials Crisis: Is Open Access A Viable Solution?, Jim Shen

Quill & Scope

his work provides an overview on open access publishing.

Two Diamantes, Jordan Teitelbaum

Quill & Scope

No abstract provided.

Tried & Fried, Jordan Teitelbaum

Quill & Scope

No abstract provided.

A Nutty Approach To Disease Prevention, Amin Esfahani

Quill & Scope

Tree nuts are healthy foods with a favourable macro- and micronutrient profile. They are low in sat-urated fats and high in mono- and polyunsaturated fatty acids. They are also good sources of vegeta-ble protein, fiber, phytosterols, polyphenols, vitamins and minerals. Because of this healthy nutrient profile, it has been postulated that tree nuts may play a significant role in health maintenance and disease prevention. The purpose of this paper is 1) to provide a brief overview of the current scien-tific evidence on the role of tree nuts in prevention and management of diabetes and heart disease and 2) to outline …

Efficient Replication Of Over 180 Genetic Associations With Self-Reported Medical Data, Joyce Y. Tung, Chuong B. Do, David A. Hinds, Amy K. Kiefer, J. Michael Macpherson, Arnab B. Chowdry, Uta Francke, Brian Naughton, Joanna Mountain, Anne Wojcicki, Nicholas Eriksson

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

While the cost and speed of generating genomic data have come down dramatically in recent years, the slow pace of collecting medical data for large cohorts continues to hamper genetic research. Here we evaluate a novel online framework for obtaining large amounts of medical information from a recontactable cohort by assessing our ability to replicate genetic associations using these data. Using web-based questionnaires, we gathered self-reported data on 50 medical phenotypes from a generally unselected cohort of over 20,000 genotyped individuals. Of a list of genetic associations curated by NHGRI, we successfully replicated about 75% of the associations that we …

Survey Of Young People In Egypt (Sype) 2009—Final Report [Arabic], Population Council

Poverty, Gender, and Youth

Responding to a dearth of data on youth in Egypt, the Population Council conducted a comprehensive situation analysis of Egyptian adolescents and young people: the Survey of Young People in Egypt (SYPE) 2009, which covered a nationally representative sample of 15,029 young people aged 10–29. SYPE collected data on the five key life transitions of education, work, family formation; health; and civic and political participation. SYPE follows up an earlier survey conducted by the Population Council in 1997, The Adolescence and Social Change in Egypt (ASCE) survey. SYPE updates the results provided by the earlier survey and expands their scope. …

Les Coûts Du Mariage—Les Transactions Matrimoniales Dans Le Monde En Développement, Sajeda Amin, Ashish Bajracharya

Poverty, Gender, and Youth

Au cours des deux dernières décennies, le Population Council a receuilli une multitude d'informations sur les causes et les corrélats du mariage des enfants et documenté ses effets néfastes sur le bien-être des femmes et des filles. Dans de nombreuses régions du monde en développement, la compréhension du mariage des enfants est au coeur de la conception de programmes qui favorisent des transitions saines vers l'âge adulte. Les travaux de recherche du Population Council soulignent également l'importance des rituels et des pratiques d'échange matrimoniales dans le monde et éclairent les différences considérables entre ces pratiques. Promouvoir des transitions vers l'âge …