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2010

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Articles 4381 - 4410 of 5702

Full-Text Articles in Medicine and Health Sciences

The Adolescent Experience In-Depth: Using Data To Identify And Reach The Most Vulnerable Young People—Egypt 2008, Population Council Jan 2010

The Adolescent Experience In-Depth: Using Data To Identify And Reach The Most Vulnerable Young People—Egypt 2008, Population Council

Poverty, Gender, and Youth

“The Adolescent Experience In-Depth: Using Data to Identify and Reach the Most Vulnerable Young People: Egypt 2008” is part of a series of Population Council guides that draw principally on data from the Demographic and Health Surveys to provide decisionmakers at all levels—from governments, nongovernmental organizations, and advocacy groups—with evidence on the situation of adolescent girls and boys and young women aged 10–24 years. The data are presented in graphs, tables, and maps (wherever possible), providing multiple formats to make the information accessible to a range of audiences. Section I is the Foreword. Section II offers brief technical notes specific …


Romance And Sex Before Marriage Among Young Women And Men In India, International Institute For Population Sciences (Iips), Population Council Jan 2010

Romance And Sex Before Marriage Among Young Women And Men In India, International Institute For Population Sciences (Iips), Population Council

Poverty, Gender, and Youth

This policy brief was produced in association with the International Institute for Population Sciences, Mumbai (IIPS). Data was drawn from the Youth in India: Situation and Needs study to examine pre-marital partnerships and relationship among youth in India. Findings call for family life or sex education, and increased awareness and education of condom use.


Schooling And Conflict In Darfur: A Snapshot Of Basic Education Services For Displaced Children, Cynthia B. Lloyd, Safaa El-Kogali, Jenny Perlman Robinson, Johanna Rankin, Ali Rashed Jan 2010

Schooling And Conflict In Darfur: A Snapshot Of Basic Education Services For Displaced Children, Cynthia B. Lloyd, Safaa El-Kogali, Jenny Perlman Robinson, Johanna Rankin, Ali Rashed

Poverty, Gender, and Youth

Schooling and Conflict in Darfur, a joint project of the Population Council and the Women's Refugee Commission, is a report based on a 2008 survey designed to provide a more accurate picture of the state of formal and non-formal education for displaced children of primary school age (6-14) in North and West Darfur. The findings are based on a scientifically selected sample of internally displaced persons (IDP) communities in North and West Darfur. The goal of the report is to provide donors, policymakers, and practitioners information to help plan and implement effective, targeted education programs for internally displaced children in …


Health And Social Consequences Of Marital Violence: A Synthesis Of Evidence From India, Shireen J. Jejeebhoy, K.G. Santhya, Rajib Acharya Jan 2010

Health And Social Consequences Of Marital Violence: A Synthesis Of Evidence From India, Shireen J. Jejeebhoy, K.G. Santhya, Rajib Acharya

Poverty, Gender, and Youth

This review paper was produced with support from UNFPA (United Nations Population Fund), and synthesizes what is known about the health and social consequences of marital violence for women in India. The review focuses on sexual, reproductive and child health consequences, including contraceptive use, experience of symptoms of infection, pregnancy-related care, unintended pregnancy and abortion, fetal, perinatal and early childhood mortality; maternal and child nutrition; and mental health outcomes. It also reviews evidence of a range of social outcomes including substance use, women's autonomy and self-efficacy; and inter-generational effects (witnessing parental violence when growing up).


White Paper: Enhancing Adolescent Financial Capabilities Through Financial Education In Bangladesh, Sajeda Amin, Laila Rahman, Sigma Ainul, Ubaidur Rob, Bushra Zaman, Rinat Akter Jan 2010

White Paper: Enhancing Adolescent Financial Capabilities Through Financial Education In Bangladesh, Sajeda Amin, Laila Rahman, Sigma Ainul, Ubaidur Rob, Bushra Zaman, Rinat Akter

Poverty, Gender, and Youth

This white paper addresses a growing concern about the problems of financial exclusion of the poor. It is based on a scoping study and a pilot program providing financial education to adolescents in Bangladesh. The Population Council worked with BRAC and Underprivileged Children’s Educational Program (UCEP) to expand these life skills. The result and tools of the study inspired UCEP to commit introduction of financial literacy in 52 schools for the under privileged children from next year while BRAC expressed interest to accumulate resources and initiate discussions with their donors and consortium partners for gradually introducing the financial literacy in …


Ethiopia Gender Survey: A Study In Seven Regions, Annabel Erulkar, Abebaw Ferede, Worku Ambelu, Woldemariam Girma, Helen Amdemikael, Behailu Gebremedhin, Berhanu Legesse, Ayehualem Tameru, Messay Teferi Jan 2010

Ethiopia Gender Survey: A Study In Seven Regions, Annabel Erulkar, Abebaw Ferede, Worku Ambelu, Woldemariam Girma, Helen Amdemikael, Behailu Gebremedhin, Berhanu Legesse, Ayehualem Tameru, Messay Teferi

Poverty, Gender, and Youth

“Ethiopia Gender Survey: A Study in Seven Regions” is a 2009 population-based survey. Over 8,000 Ethiopian women aged 15 to 49 were interviewed to examine a better understanding of HIV behavior, gender issues and reproductive health in Ethiopia. The information serves as the baseline survey for four initiatives in Ethiopia related to adolescent health and development, gender-based violence, women’s empowerment, and female genital cutting/ mutilation.


Family Level Phylogenies Reveal Modes Of Macroevolution In Rna Viruses, Andrew Kitchen, Laura Shackelton, Edward Holmes Jan 2010

Family Level Phylogenies Reveal Modes Of Macroevolution In Rna Viruses, Andrew Kitchen, Laura Shackelton, Edward Holmes

United States Public Health Resources

Despite advances in understanding the patterns and processes of microevolution in RNA viruses, little is known about the determinants of viral diversification at the macroevolutionary scale. In particular, the processes by which viral lineages assigned as different “species” are generated remain largely uncharacterized. To address this issue, we use a robust phylogenetic approach to analyze patterns of lineage diversification in five representative families of RNA viruses. We ask whether the process of lineage diversification primarily occurs when viruses infect new host species, either through cross-species transmission or codivergence, and which are defined here as analogous to allopatric speciation in animals, …


Patterns Of Drug Use And Abuse Among Aging Adults With And Without Hiv: A Latent Class Analysis Of A Us Veteran Cohort, Traci C. Green, Trace Kershaw, Haiqun Lin, Robert Heimer, Joseph L. Goulet, Kevin L. Kraemer, Adam J. Gordon, Steve A. Maisto, Nancy L. Day, Kendall Bryant, David A. Fiellin, Amy C. Justice Jan 2010

Patterns Of Drug Use And Abuse Among Aging Adults With And Without Hiv: A Latent Class Analysis Of A Us Veteran Cohort, Traci C. Green, Trace Kershaw, Haiqun Lin, Robert Heimer, Joseph L. Goulet, Kevin L. Kraemer, Adam J. Gordon, Steve A. Maisto, Nancy L. Day, Kendall Bryant, David A. Fiellin, Amy C. Justice

United States Public Health Resources

This study characterized the extent and patterns of self-reported drug use among aging adults with and without HIV, assessed differences in patterns by HIV status, and examined pattern correlates. Data derived from 6351 HIV-infected and uninfected adults enrolled in an eight-site matched cohort, the Veterans Aging Cohort Study (VACS). Using clinical variables from electronic medical records and sociodemographics, drug use consequences, and frequency of drug use from baseline surveys, we performed latent class analyses (LCA) stratified by HIV status and adjusted for clinical and socio-demographic covariates. Participants were, on average, age 50 (range 22–86), primarily male (95%) and African-American (64%). …


Female Veterans Of The Oef/Oif Conflict: Concordance Of Ptsd Symptoms And Substance Misuse, Sarah E. Nunnink, Gali Goldwaser, Pia S. Heppner, James O.E. Pittman, Caroline M. Nievergelt, Dewleen G. Baker Jan 2010

Female Veterans Of The Oef/Oif Conflict: Concordance Of Ptsd Symptoms And Substance Misuse, Sarah E. Nunnink, Gali Goldwaser, Pia S. Heppner, James O.E. Pittman, Caroline M. Nievergelt, Dewleen G. Baker

United States Public Health Resources

This study examined the post-deployment rates of comorbid PTSD and substance abuse in a cohort of female veterans who served in Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF). Female OEF/ OIF veterans and reservists (N=36) completed a battery of assessments as part of a larger study. Of the 36 participants, 11 (31%) screened positive for posttraumatic stress disorder (PTSD), 17 (47%) screened positive for high-risk drinking and 2 (6%) screened positive for drug abuse. Higher scores on measures of alcohol and drug use predicted positive PTSD status (p≤0.01) and alcohol misuse was significant in explaining …


Understanding Attitudes Toward People With Down Syndrome, Jill E. Pace, Mikyong Shin, Sonja A. Rasmussen Jan 2010

Understanding Attitudes Toward People With Down Syndrome, Jill E. Pace, Mikyong Shin, Sonja A. Rasmussen

United States Public Health Resources

Understanding attitudes of the public toward people with Down syndrome is important because negative attitudes might create barriers to social integration, which can affect their success and quality of life. We used data from two 2008 U.S. surveys (HealthStyles© survey of adults 18 years or older and YouthStyles© survey of youth ages 9–18) that asked about attitudes toward people with Down syndrome, including attitudes toward educational and occupational inclusion and toward willingness to interact with people with Down syndrome. Results showed that many adults continue to hold negative attitudes toward people with Down syndrome: A quarter of respondents agreed that …


Age Effect On The Gaze Stabilization Test, Julie A. Honaker Jan 2010

Age Effect On The Gaze Stabilization Test, Julie A. Honaker

Department of Special Education and Communication Disorders: Faculty Publications

Impairments of the vestibular-ocular reflex (VOR) lead to a decline in visual acuity during head movements. Dynamic visual acuity (DVA) testing is a sensitive assessment tool for detecting VOR impairments. DVA evaluates accuracy of visual acuity during fixed velocity head movements. In contrast, the Gaze Stabilization test (GST) is a new functional evaluation of the VOR that identifies a person’s maximum head velocity (in degrees per second) a person can maintain with stable vision of a target (i.e. optotype). The objective of this study was to evaluate the effect of age on the GST in participants without vestibular disease. The …


Michigan Bovine Tuberculosis: Annotated Bibliography Jan 2010

Michigan Bovine Tuberculosis: Annotated Bibliography

Michigan Bovine Tuberculosis Bibliography and Database

The bibliography includes 259 research publications from the years 1930-2010. It is international in scope, including articles relating to North and South America, Africa, Europe, Australia, and New Zealand. It includes journal articles, dissertations, government publications, reports, and proceedings. Each publication entry includes citation, abstract, and key words.

The bibliography (PDF) was generated from an MS Access database. A "zipped" version of that database is attached below as a related file (it is approximately 175 Mb)


Evaluation Of A Rapid Serological Test For The Determination Of Mycobacterium Bovis Infection In Badgers (Meles Meles) Found Dead, Mark A. Chambers, Konstantin P. Lyashchenko, Rena Greenwald, Javan Esfandiari, Eurig James, Leslie Barker, Jeff Jones, Gavin Watkins, Simon Rolfe Jan 2010

Evaluation Of A Rapid Serological Test For The Determination Of Mycobacterium Bovis Infection In Badgers (Meles Meles) Found Dead, Mark A. Chambers, Konstantin P. Lyashchenko, Rena Greenwald, Javan Esfandiari, Eurig James, Leslie Barker, Jeff Jones, Gavin Watkins, Simon Rolfe

Michigan Bovine Tuberculosis Bibliography and Database

Between October 2005 and May 2006, a total of 727 badgers found dead in Wales were reported, and 550 were delivered to the Regional Laboratories of the Veterinary Laboratories Agency (VLA). Of the 459 carcasses suitable for examination, 55 were deemed to be infected with Mycobacterium bovis on the basis of culture, spoligotyping, and variable-number tandem repeat typing. Acid-fast bacteria were observed histologically in a further six badgers, but these bacteria were not confirmed as M. bovis by culture. A rapid serological test (BrockTB Stat-Pak) performed on thoracic blood showed a sensitivity of 35% and a specificity of 99%. Presence …


Estimating The Extent Of Spatial Association Of Mycobacterium Bovis Infection In Badgers In Ireland, G. E. Kelly, G. E. Mcgrath, S. J. More Jan 2010

Estimating The Extent Of Spatial Association Of Mycobacterium Bovis Infection In Badgers In Ireland, G. E. Kelly, G. E. Mcgrath, S. J. More

Michigan Bovine Tuberculosis Bibliography and Database

Mycobacterium bovis infects the wildlife species badgers Meles meles who are linked with the spread of the associated disease tuberculosis (TB) in cattle. Control of livestock infections depends in part on the spatial and social structure of the wildlife host. Here we describe spatial association of M. bovis infection in a badger population using data from the first year of the Four Area Project in Ireland. Using second-order intensity functions, we show there is strong evidence of clustering of TB cases in each the four areas, i.e. a global tendency for infected cases to occur near other infected cases. Using …


Emergence Of Diseases From Wildlife Reservoirs, J. C. Rhyan, T. R. Spraker Jan 2010

Emergence Of Diseases From Wildlife Reservoirs, J. C. Rhyan, T. R. Spraker

Michigan Bovine Tuberculosis Bibliography and Database

Interest in the epidemiology of emerging diseases of humans and livestock as they relate to wildlife has increased greatly over the past several decades. Many factors, most anthropogenic, have facilitated the emergence of diseases from wildlife. Some livestock diseases have ‘‘spilled over’’ to wildlife and then ‘‘spilled back’’ to livestock. When a population is exposed to an infectious agent, depending on an interaction of factors involving the host, agent, and environment, the population may be resistant to infection or may become a dead-end host, a spillover host, or a maintenance host. Each exposure is unique; the same species of host …


Economic Burden Of Ventilator-Associated Pneumonia Based On Total Resource Utilization, Marcos I. Restrepo, Antonio Anzueto, Alejandro C. Arroliga, Bekele Afessa, Mark J. Atkinson, Ngoc J. Ho, Regina Schinner, Ronald L. Bracken, Marin H. Kollef Jan 2010

Economic Burden Of Ventilator-Associated Pneumonia Based On Total Resource Utilization, Marcos I. Restrepo, Antonio Anzueto, Alejandro C. Arroliga, Bekele Afessa, Mark J. Atkinson, Ngoc J. Ho, Regina Schinner, Ronald L. Bracken, Marin H. Kollef

Open Access Publications

No abstract provided.


Attributable Costs Of Surgical Site Infection And Endometritis After Low Transverse Cesarean Delivery, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Barton H. Hamilton, Victoria J. Fraser Jan 2010

Attributable Costs Of Surgical Site Infection And Endometritis After Low Transverse Cesarean Delivery, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Barton H. Hamilton, Victoria J. Fraser

Open Access Publications

No abstract provided.


Quantitative Cardiovascular Magnetic Resonance For Molecular Imaging, Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza, Samuel A. Wickline Jan 2010

Quantitative Cardiovascular Magnetic Resonance For Molecular Imaging, Patrick M. Winter, Shelton D. Caruthers, Gregory M. Lanza, Samuel A. Wickline

Open Access Publications

No abstract provided.


Sliding Set-Points Of Immune Responses For Therapy Of Autoimmunity, Chyi-Song Hsieh, Jhoanne Lynne Bautista Jan 2010

Sliding Set-Points Of Immune Responses For Therapy Of Autoimmunity, Chyi-Song Hsieh, Jhoanne Lynne Bautista

Open Access Publications

No abstract provided.


Defective Camp Generation Underlies The Sensitivity Of Cns Neurons To Neurofibromatosis-1 Heterozygosity, Jacquelyn A. Brown, Scott M. Gianino, David H. Gutmann Jan 2010

Defective Camp Generation Underlies The Sensitivity Of Cns Neurons To Neurofibromatosis-1 Heterozygosity, Jacquelyn A. Brown, Scott M. Gianino, David H. Gutmann

Open Access Publications

No abstract provided.


Ret Signaling Is Required For Survival And Normal Function Of Nonpeptidergic Nociceptors, Judith P. Golden, Masato Hoshi, Mohammed A. Nassar, Hideki Enomoto, John N. Wood, Jeffrey Milbrandt, Robert W. Gereau Iv, Eugene M. Johnson Jr, Sanjay Jain Jan 2010

Ret Signaling Is Required For Survival And Normal Function Of Nonpeptidergic Nociceptors, Judith P. Golden, Masato Hoshi, Mohammed A. Nassar, Hideki Enomoto, John N. Wood, Jeffrey Milbrandt, Robert W. Gereau Iv, Eugene M. Johnson Jr, Sanjay Jain

Open Access Publications

No abstract provided.


Vav2 And Vav3 As Candidate Disease Genes For Spontaneous Glaucoma In Mice And Humans, Keiko Fujikawa, Takeshi Iwata, Kaoru Inoue, Masakazu Akahori, Hanako Kadotani, Masahiro Fukaya, Masahiko Watanabe, Qing Chang, Edward M. Barnett, Wojciech Swat Jan 2010

Vav2 And Vav3 As Candidate Disease Genes For Spontaneous Glaucoma In Mice And Humans, Keiko Fujikawa, Takeshi Iwata, Kaoru Inoue, Masakazu Akahori, Hanako Kadotani, Masahiro Fukaya, Masahiko Watanabe, Qing Chang, Edward M. Barnett, Wojciech Swat

Open Access Publications

No abstract provided.


The Arf Tumor Suppressor Regulates Bone Remodeling And Osteosarcoma Development In Mice, Daniel A. Rauch, Michelle A. Hurchla, John C. Harding, Hongju Deng, Lauren K. Shea, Mark C. Eagleton, Stefan Niewiesk, Michael D. Lairmore, David Piwnica-Worms, Thomas J. Rosol, Jason D. Weber, Lee Ratner, Katherine N. Weilbaecher Jan 2010

The Arf Tumor Suppressor Regulates Bone Remodeling And Osteosarcoma Development In Mice, Daniel A. Rauch, Michelle A. Hurchla, John C. Harding, Hongju Deng, Lauren K. Shea, Mark C. Eagleton, Stefan Niewiesk, Michael D. Lairmore, David Piwnica-Worms, Thomas J. Rosol, Jason D. Weber, Lee Ratner, Katherine N. Weilbaecher

Open Access Publications

No abstract provided.


Melanoma Differentiation-Associated Gene 5 (Mda5) Is Involved In The Innate Immune Response To Paramyxoviridae Infection In Vivo, Leonid Gitlin, Loralyn Benoit, Christina Song, Marina Cella, Susan Gilfillan, Michael J. Holtzman, Marco Colonna Jan 2010

Melanoma Differentiation-Associated Gene 5 (Mda5) Is Involved In The Innate Immune Response To Paramyxoviridae Infection In Vivo, Leonid Gitlin, Loralyn Benoit, Christina Song, Marina Cella, Susan Gilfillan, Michael J. Holtzman, Marco Colonna

Open Access Publications

No abstract provided.


Aromatase Gene Polymorphisms Are Associated With Survival Among Patients With Cardiovascular Disease In A Sex-Specific Manner, Amber L. Beitelshees, Julie A. Johnson, Megan L. Hames, Yan Gong, Rhonda M. Cooper-Dehoff, Jun Wu, Sharon Cresci, Cynthia X. Ma, Carl J. Pepine, Michael A. Province, John A. Spertus, Howard L. Mcleod Jan 2010

Aromatase Gene Polymorphisms Are Associated With Survival Among Patients With Cardiovascular Disease In A Sex-Specific Manner, Amber L. Beitelshees, Julie A. Johnson, Megan L. Hames, Yan Gong, Rhonda M. Cooper-Dehoff, Jun Wu, Sharon Cresci, Cynthia X. Ma, Carl J. Pepine, Michael A. Province, John A. Spertus, Howard L. Mcleod

Open Access Publications

No abstract provided.


Altered Lung Morphogenesis, Epithelial Cell Differentiation And Mechanics In Mice Deficient In The Wnt/Beta-Catenin Antagonist Chibby, Damon Love, Feng-Qian Li, Michael C. Burke, Benjamin Cyge, Masao Ohmitsu, Jeffery Cabello, Janet E. Larson, Steven L. Brody, J. Craig Cohen, Ken-Ichi Takemaru Jan 2010

Altered Lung Morphogenesis, Epithelial Cell Differentiation And Mechanics In Mice Deficient In The Wnt/Beta-Catenin Antagonist Chibby, Damon Love, Feng-Qian Li, Michael C. Burke, Benjamin Cyge, Masao Ohmitsu, Jeffery Cabello, Janet E. Larson, Steven L. Brody, J. Craig Cohen, Ken-Ichi Takemaru

Open Access Publications

No abstract provided.


Chlorella Viruses Encode Most, If Not All, Of The Machinery To Glycosylate Their Glycoproteins Independent Of The Endoplasmic Reticulum And Golgi, James L. Van Etten, James Gurnon, Giane M. Yanai-Balser, David Dunigan, Michael V. Graves Jan 2010

Chlorella Viruses Encode Most, If Not All, Of The Machinery To Glycosylate Their Glycoproteins Independent Of The Endoplasmic Reticulum And Golgi, James L. Van Etten, James Gurnon, Giane M. Yanai-Balser, David Dunigan, Michael V. Graves

Nebraska Center for Virology: Faculty Publications

In contrast to all other viruses that use the host machinery located in the endoplasmic reticulum and Golgi to glycosylate their glycoproteins, the large dsDNA-containing chlorella viruses encode most, if not all, of the components to glycosylate their major capsid proteins. Furthermore, all experimental results indicate that glycosylation occurs independent of the endoplasmic reticulum and Golgi. (Review article)


History Of Medicine Schedule 2010-2011, Houston History Of Medicine Society Jan 2010

History Of Medicine Schedule 2010-2011, Houston History Of Medicine Society

Houston History of Medicine Lectures (2006-2012)

  • William Osler (1849-1919): America’s Most Famous Physician (Robert E. Rakel)
  • The Assassination of John F. Kennedy: A Neurosurgeon’s Eyewitness Account of the Medical Aspect of the Events of November 22, 1963 (Robert G. Grossman)
  • Making Cancer History: Disease and Discovery at the University of Texas M.D. Anderson Cancer Center (James S. Olson)
  • The History of Pathology as a Biological Science and Medical Specialty (L. Maximillian Buja)
  • “Medicine in the Mid-19th Century America” (Student Essay Contest Winner) (David Hunter)
  • The Achievements and Enduring Relevance of Rudolph Virchow (Nathan Grohmann)
  • Medicine: Perspectives in History and Art (Robert E. Greenspan)
  • What Every Physician …


State Agency Promising Practice: Massachusetts - Using A Collaborative, Person-Centered Planning Approach To Facilitate Community Employment, Jennifer Bose, Jaimie Ciulla Timmons, Thinkwork! At The Institute For Community Inclusion At Umass Boston Jan 2010

State Agency Promising Practice: Massachusetts - Using A Collaborative, Person-Centered Planning Approach To Facilitate Community Employment, Jennifer Bose, Jaimie Ciulla Timmons, Thinkwork! At The Institute For Community Inclusion At Umass Boston

ThinkWork! Publications

The Northeast Region Supported Employment Project was developed by the North Shore area office of the Massachusetts Department of Developmental Services in 2007. This pilot program, open to any individual with ID/DD who wanted to work, emphasized a person-centered planning approach to achieving the individuals’ goals for employment in the community. The project emphasized the individual’s choice of employment providers, collaboration with the Massachusetts Rehabilitation Commission (MRC), and use of an independent facilitator to support career and life planning. The project was spearheaded by two DDS administrators dedicated to communicating the value of community-based employment to the Department.


State Agency Promising Practice: Maryland - Collaborating To Promote Self-Employment For People With Intellectual/Developmental Disabilities, Jennifer Bose, Thinkwork! At The Institute For Community Inclusion At Umass Boston Jan 2010

State Agency Promising Practice: Maryland - Collaborating To Promote Self-Employment For People With Intellectual/Developmental Disabilities, Jennifer Bose, Thinkwork! At The Institute For Community Inclusion At Umass Boston

ThinkWork! Publications

Self-employment has emerged as a viable option for individuals with intellectual or developmental disabilities (IDD). To meet increased self-employment demands, Maryland’s Developmental Disabilities Administration (DDA), in collaboration with the Maryland Division of Rehabilitation Services (DORS), adapted services offered through the Reach Independence through Self Employment (RISE) program. The RISE program, funded by DORS, provides technical assistance and financial support to people starting their own businesses. DDA’s role in this self-employment initiative has helped people with IDD start a wide variety of businesses and achieve meaningful employment.