Medicine and Health Sciences Commons^™

Role Of Flgt In Anchoring The Flagellum Of Vibrio Cholerae, Raquel M. Martinez, Brooke A. Jude, Thomas J. Kirn, Karen Skorupski, Ronald K. Taylor

Dartmouth Scholarship

Flagellar motility has long been regarded as an important virulence factor. In Vibrio cholerae, the single polar flagellum is essential for motility as well as for proper attachment and colonization. In this study, we demonstrate that the novel flagellar protein FlgT is involved in anchoring the flagellum to the V. cholerae cell. A screen for novel colonization factors by use of TnphoA mutagenesis identified flgT. An in-frame deletion of flgT established that FlgT is required for attachment, colonization, and motility. Transmission electron microscopy revealed that while the flgT mutant is capable of assembling a phenotypically normal flagellum, …

Social Support, Problem Solving, And The Longitudinal Course Of Newlywed Marriage, Kieran T. Sullivan, Lauri A. Pasch, Matthew D. Johnson, Thomas N. Bradbury

Psychology

Married couples (N = 172) were observed as newlyweds and again one year later while engaging in 2 problem-solving and 2 personal support discussions. Microanalytic coding of these conversations was used to examine associations between problem-solving and social support behaviors over one year and their relative contributions to 10-year trajectories of self-reported relationship satisfaction and dissolution. Results demonstrated that initially lower levels of positive support behaviors and higher levels of negative support behaviors predicted 1-year increases in negative emotion displayed during problem-solving conversations. Emotions coded from the initial problem-solving conversations did not predict 1-year changes in social support behaviors. Controlling …

Addressing Cultural Barriers In Australia’S Acute Care System: Problems The United States Can Learn From, Allison Reilly

Inquiry Journal 2010

No abstract provided.

The Many Faces Of Health: Dialogue And Research At The University Of New Hampshire, Emily D. Robbins

Inquiry Journal 2010

No abstract provided.

Living Positively: An Inside Look At Hiv Counseling And Testing In Uganda, Lindsay Bergmann

Inquiry Journal 2010

No abstract provided.

Dental Maturity Amongst Various Vertical And Sagittal Facial Patterns, Rashna H. Sukhia, Mubassar Fida

Section of Dental-Oral Maxillofacial Surgery

OBJECTIVE: To compare the mean dental maturity amongst three vertical facial patterns (short, average and long anterior facial heights) and also amongst two sagittal facial patterns (skeletal class I and II) in orthodontic patients.

STUDY DESIGN: Cross-sectional analytical study.

PLACE AND DURATION OF STUDY: The Aga Khan University Hospital, Karachi, from August to October 2008.

METHODOLOGY: Data was retrospectively retrieved from pretreatment orthodontic records of patients who visited the orthodontic clinic. The sample was divided into three vertical groups, namely short, average and long anterior facial types, and two sagittal groups, namely skeletal class I and II. Dental development was …

Birth Order Modifies The Effect Of Il13 Gene Polymorphisms On Serum Ige At Age 10 And Skin Prick Test At Ages 4, 10 And 18: A Prospective Birth Cohort Study, Ikechukwu U. Ogbuanu, Wilfried J. Karmaus, Hongmei Zhang, Tara Sabo-Attwood, Susan L. Ewart, Graham Roberts, Syed Hasan Arshad

Faculty Publications

Background: Susceptibility to atopy originates from effects of the environment on genes. Birth order has been identified as a risk factor for atopy and evidence for some candidate genes has been accumulated; however no study has yet assessed a birth order-gene interaction.

Objective: To investigate the interaction of IL13 polymorphisms with birth order on allergic sensitization at ages 4, 10 and 18 years.

Methods: Mother-infant dyads were recruited antenatally and followed prospectively to age 18 years. Questionnaire data (at birth, age 4, 10, 18); skin prick test (SPT) at ages 4, 10, 18; total serum IgE and specific inhalant screen …

Associations Between Polycyclic Aromatic Hydrocarbon-Related Exposures And P53 Mutations In Breast Tumors, Irina Mordukhovich, Pavel Rossner Jr., Mary Beth Terry, Regina M. Santella, Yu-Jing Zhang, Hanina Hibshoosh, Lorenzo Memeo, Mahesh Mansukhani, Chang-Min Long, Gail Garbowski, Meenakshi Agrawal, Mia M. Gaudet, Susan E. Steck, Sharon K. Sagiv, Sybil M. Eng, Susan L. Teitelbaum, Alfred I. Neugut, Kathleen Conway-Dorsey, Marilie D. Gammon

Faculty Publications

BACKGROUND: Previous studies have suggested that polycyclic aromatic hydrocarbons (PAHs) may be associated with breast cancer. However, the carcinogenicity of PAHs on the human breast remains unclear. Certain carcinogens may be associated with specific mutation patterns in the p53 tumor suppressor gene, thereby contributing information about disease etiology.

OBJECTIVES: We hypothesized that associations of PAH-related exposures with breast cancer would differ according to tumor p53 mutation status, effect, type, and number.

METHODS: We examined this possibility in a population-based case–control study using polytomous logistic regression. As previously reported, 151 p53 mutations among 859 tumors were identified using Surveyor nuclease and …

Group B Streptococcus Intrapartum Prophylaxis Guidelines Adherence: A Perinatal Risk Management Issue, Lisa Hanson, Leona Vandevusse

College of Nursing Faculty Research and Publications

No abstract provided.

T-786c Polymorphism Of The Endothelial Nitric Oxide Synthase Gene And Neuralgia-Inducing Cavitational Osteonecrosis Of The Jaws, Charles J Glueck, Robert E Mcmahon, Jerry E Bouquot, Naseer A Khan, Ping Wang

Faculty, Staff and Student Publications

OBJECTIVE: We hypothesized that, similar to idiopathic hip osteonecrosis, the T-786C mutation of the endothelial nitric oxide synthase (eNOS) gene affecting nitric oxide (NO) production was associated with neuralgia-inducing cavitational osteonecrosis of the jaws (NICO). DESIGN: In 22 NICO patients, not having taken bisphosphonates, mutations affecting NO production (eNOS T-786C, stromelysin 5A6A) were measured by polymerase chain reaction. Two healthy normal control subjects were matched per case by race and gender. RESULTS: Homozygosity for the mutant eNOS allele (TT) was present in 6 out of 22 patients (27%) with NICO compared with 0 out of 44 (0%) race and gender-matched …

Lower-Limb Alignment And Posterior Tibial Slope In Pakistanis: A Radiographic Study, Mujahid Jamil Khattak, Masood Umer, Edward T Davis, Munira Habib, Mehmood Ahmed

Department of Surgery Docs

Abstract

PURPOSE:

To assess the lower-limb alignment and posterior tibial slope in Pakistanis.

METHODS:

40 male and 19 female healthy Pakistanis aged 20 to 45 years were recruited. A full weight-bearing anteroposterior radiograph of the entire lower limb of each subject was obtained. The axial alignment was measured based on the centres of the femoral head, knee, and ankle. The tibiofemoral (TF) angle, knee joint line obliquity angle (angle J), and posterior tibial slope were determined.

RESULTS:

The mean TF angle was more varus in men than women (178.4 degrees vs. 180.0 degrees, p<0.001). The mean angle J was more medially inclined in men than women (93.4 degrees vs. 91.4 degrees, p=0.007). The mean medial tibial slope was greater in women than men (16.0 degrees vs. 12.5 degrees, p<0.001). The posterior tibial slope was greater in women than men (14.1 degrees vs. 12.5 degrees, p=0.02), and was greater than the 5 degrees to 10 degrees commonly reported.

CONCLUSIONS:

Knee alignment and geometry vary …

Volume 03, Cheryl Peck, Charles Hoever, Longwood Theater Department, Brittany Anderson, J. Ervin Sheldon, Richard Hayden, Yuri Calustro, Candice Fleming, Rebecca Franklin, Ashley Yocum, Danielle M. Jagoda, Cristina M. Valdivieso, Jameka Jones, Amy Ellis, Ashley Maser, Erikk Shupp, Jamie Yurasits, Joshua Davis, Alexander Leonhart, Kenny Wolfe, Sally Meadows, J. Haley, Amy Jackson, Morgan Howard, Adrienne Heinbaugh, Melissa Dorton, Ciarra Stalker

Incite: The Journal of Undergraduate Scholarship

Introduction from Dean Dr. Charles Ross

Little Shop of Horrors by Longwood Theater Department

Who Has the Hottest Hotsauce in Farmville: A Quantitative Comparison of Sauces from Local Restaurants by Cheryl Peck and Charles Hoever

Precipitation Effects on the Growth of White Oaks and Virginia Pines on the Mt. Vernon Plantation by Brittany Anderson

Design and Synthesis of Novel Ion Binding Molecules for Self-Assembly and Sensing Applications by J. Ervin Sheldon

A Statistical Analysis of Algorithms for Playing SameGame by Richard Hayden

Intersecting Cylinders at Arbitrary Angles by Yuri Calustro

Putting a Foot in the Revolving Door: Strategies for Reducing …

Lsuhsc Facilities Biweekly Update: April 2010, Lsuhsc Property And Facilities Management

LSUHSC Facilities Biweekly Updates: 2010

LSUHSC Facilities Biweekly Updates from April 9 and 23, 2010.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Lsuhsc Facilities Daily Update: April 2010, Lsuhsc Property And Facilities Management

LSUHSC Facilities Daily Updates: 2010

LSUHSC Facilities Daily Updates from April 2010.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

A Randomized Trial Of Bilevel Positive Airway Pressure Device And High Flow Oxygen For Persistent Dyspnea In, David Hui

Dissertations and Theses (Open Access)

Background: Dyspnea is a common and distressing symptom among patients with advanced cancer. The role of bilevel positive airway pressure (BIPAP) and Vapotherm in the relief of dyspnea have not been well defined. We aimed to determine and to compare the efficacy of BIPAP and VapoTherm for cancer related dyspnea.

Methods: In this randomized, open-label, crossover study, we randomly assigned advanced cancer patients with persistent dyspnea >=3/10 to either Vapotherm for 2 hours followed by BiPAP for 2 hours, or BiPAP followed by Vaptherm. A variable washout period was instituted between interventions. The primary end point was change in numeric …

Ureteroscopic Laser Treatment Of Upper Urinary Tract Neoplasms., Demetrius H. Bagley, Michael Grasso

Department of Radiology Faculty Papers

BACKGROUND: Endoscopic management of upper urinary tract transitional cell carcinoma has assumed an important role in diagnosis and treatment. The introduction of small diameter rigid and flexible ureteroscopes has permitted access to the upper tract. Biopsy techniques have been developed for accurate diagnosis, and the addition of lasers has given the urologists an excellent tool for treatment. METHODS: Medical literature available relative to the endoscopic laser treatment of upper tract neoplasms has been reviewed. RESULTS: Ureteroscopic treatment has been characterized by good success with high recurrence rates, both in the upper tract and in the bladder. Bladder recurrence rates are …

Giving Birth: The Voices Of Ecuadorian Women, Lynn Clark Callister, Cheryl A. Corbett, Shelly Reed, Cassidy Tomao, Katie G. Thornton

Faculty Publications

Purpose: The purpose of this ethnographic study was to describe the perceptions of Ecuadorian childbearing women. Background: No studies published in English could be found documenting the perspectives of Ecuadorian childbearing women about their birth experiences. Method: Thirty-two women who had recently given birth in Guayaquil, Ecuador participated in audiotaped interviews, which were analyzed as appropriate for ethnographic inquiry. Results: “Enduring birth to obtain the gift” was the overarching theme. Supporting themes included caring for self and accessing prenatal care to have a healthy newborn; relying on God to ensure positive maternal/newborn outcomes; submission of self to healthcare providers because …

The Effect Of Arm Dominance On Specimen Integrity When Sampling Blood From Iv Catheters, Jay M. Andross

Nursing Masters

The purpose of this study was to examine whether or not arm dominance contributes to rates of hemolysis in blood samples that are drawn from intravenous catheters at the time of their initial placement. A quantitative, prospective, quasi-experimental design was used. Fifty-eight subjects were randomized to either the control group who had blood drawn through an IV catheter placed in their dominant arm or the experimental group for whom the non-dominant arm was selected. The Sarstedt Monovette collection system was used to obtain blood samples from the IV catheter. Overall, blood specimens demonstrated a very low rate of hemolysis. Only …

Using A Self-Learning Module To Teach Nurses About Caring For Patients With Eating Disorders, Carrie Steinwachs

Nursing Masters

Background: The rate of eating disorders is on a rise, especially in adolescents. Eating disorders are very serious and can cause detrimental health problems requiring hospitalizations. Due to the many complications associated with eating disorders, nurses who care for these patients should have proper training and education regarding the disease and its ‟ treatments. Purpose : The purpose of this study was to increase nurse‟s knowledge about caring for patients with eating disorders along with determining the effectiveness of using a self-learning module (SLM) as a teaching method. Methods: A pre and post-assessment test was used in this study. Participants …

Occipital Nerve Stimulator Systems: Review Of Complications And Surgical Techniques, Steven Falowski, Dajie Wang, Arvind Sabesan, Ashwini Sharan

Department of Neurosurgery Faculty Papers

Introduction: Stimulation of the occipital nerves is becoming more widely accepted in the treatment of occipital neuritis and migraine disorders.

Objective: Presently, equipment available for spinal cord stimulation is adapted for insertion into the subcutaneous space over the occipital nerves. Many technical factors need to be reassessed to optimize the therapy.

Methods: We performed a retrospective review of patients implanted from 2003 to 2007 at a single center. We aimed to analyze the rate of surgical complications related to implantation technique. A total of 28 patients were present for analysis. Patients were followed up to 60 months with a mean …

Reliability Of Surface Electromyography During Maximal Voluntary Isometric Contractions, Jump Landings, And Cutting, Mckenzie Fauth, Erich Petushek, Christina Feldmann, Brittni Hsu, Luke Garceau, Brittney Lutsch, William Ebben

Exercise Science Faculty Research and Publications

The reliability of electromyographic (EMG) data has been examined for isometric and slow dynamic tasks, but little is known about the repeatability of this data for ballistic movements. The purpose of this study was to examine the within-session, trial-to-trial reliability of a variety of quadriceps and hamstrings muscles during isometric and ballistic activities. Data were analyzed by way of intraclass correlation coefficients (ICC), intersubject coefficients of variation (CV_inter), and intrasubject coefficients of variation (CV_intra). Twenty-four subjects performed 3 repetitions each of 2 randomly ordered test exercises, including landing from a depth jump (J) and cutting after …

Simple Linear Measurements Of The Normal Liver: Interobserver Agreement And Correlation With Hepatic Volume On Mri, Sachit K. Verma, Kristen Mcclure, Laurence Parker, Donald G. Mitchell, Manisha Verma, Diane Bergin

Department of Radiology Faculty Papers

OBJECTIVE. To retrospectively evaluate interobserver agreement for 4 manually determined linear hepatic measurements on magnetic resonance imaging (MRI) and correlation of these linear measurements with hepatic volume.

MATERIALS AND METHODS. Hepatic linear measurements: midhepatic point craniocaudad (MHP CC), maximum CC to liver tip (Max CC), maximum transverse and MHP anteroposterior (AP) dimensions were performed on 116 patients without liver disease who had 1.5 T MR imaging of the abdomen.Linear measurements: MHP CC, Max CC, maximum transverse, MHP AP dimensions and products of CC with MHP AP dimension were correlated with hepatic volumes. Correlation analysis (Pearson product moment correlation), Student t …

Relationship Of Tear Size And Location To Fatty Degeneration Of The Rotator Cuff, H. Mike Kim, Nirvikar Dahiya, Sharlene A. Teefey, Jay D. Keener, Leesa M. Galatz, Ken Yamaguchi

Open Access Publications

No abstract provided.

Gender Trends In Dental Leadership And Academics: A Twenty-Two-Year Observation, Judy Chia-Chun Yuan, Damian J. Lee, Suchada Kongkiatkamon, Sasha Ross, Soni Prasad, Anne Koerber, Cortino Sukotjo

School of Dentistry Faculty Research and Publications

The purpose of this study was to examine gender disparities in dental leadership and academics in the United States. Nine journals that represent the dental specialties and high published impact factors were selected to analyze the percentage of female dentists’ first and senior authorship for the years 1986, 1990, 1995, 2000, 2005, and 2008. Data on appointment status and female deanship were collected from the American Dental Association (ADA) survey, and the trends were studied. The proportion of female presidents in ADA-recognized specialty organizations was also calculated. Overall, the increase in first female authorship was not statistically significant, but the …

Review: Sweet Thunder: The Life And Times Of Sugar Ray Robinson, Dusty Gres

Georgia Library Quarterly

Review of "Sweet Thunder: The Life and Times of Sugar Ray Robinson," by Wil Haygood.

Post-Prandial Vomiting And Abdominal Pain: A Case Report, Hilary F. Basham Do, Kathleen Kane Md

Department of Emergency Medicine

No abstract provided.

Parotidectomy: A Review Of 112 Patients Treated At A Teaching Hospital In Pakistan, Naeem Sultan Ali, Ahmad Nawaz, Shaheryar Rajput, Mubasher Ikram

Section of Otolaryngology, Head & Neck Surgery

Objective:The Purpose of this study was to analyze the clinical presentation, histopathology and complications following parotid surgery.

Methods:

We retrospectively reviewed the charts of 112 Patients who underwent parotidectomy from January 2000 to February 2010. Data including age, sex, clinical signs and symptoms, histology and complication were collected from medical records.

Results:

Of the total, 82 (74%) had benign lesions, 30 (36%) had malignant tumors. The most common benign tumor was pleomorphic adenoma (57%), and the most common malignant tumor was mucoepidermoid carcinoma (16%). Analysis of the correlation between fine-needle aspiration cytology and final histology revealed that fine-needle aspiration …

Increase In Organization Index Predicts Atrial Fibrillation Termination With Flecainide Post-Ablation: Spectral Analysis Of Intracardiac Electrograms, Jiun Tuan, Faizel Osman, Jeilan Mohamed, Suman Kundu, Rajkumar Mantravadi, Peter J. Stafford, G. André Ng

Internal Medicine, East Africa

Aims: The mechanism of the action of flecainide in the termination of human atrial fibrillation (AF) is not fully understood. We studied the acute effects of flecainide on AF electrograms in the time and frequency domain to identify factors associated with AF termination.

Methods and results: Patients who were still in AF at the end of catheter ablation for AF were given intravenous flecainide. Dominant frequency (DF) and organization index (OI) were obtained by fast Fourier transform of electrograms from the coronary sinus catheter over 10 s in AF, before and after flecainide infusion. Mean AF cycle length (CL) was …

75 Hours, 18 Babies, Dozens Of Women, And Me: Exploring Gynecological And Obstetrical Care In Bamako, Minnie Yordon

Independent Study Project (ISP) Collection

Mali has the third highest total fertility rate in the world, with each woman having an average of 6.62 children in the year 2009. Gynecological and obstetrical care, therefore, plays a large role in the lives of these women; 70% of women attend at least one prenatal consultation over the course of their pregnancy, and a skilled attendant is present at approximately 50% of all births. In this paper, I seek a better understanding of gynecological and obstetrical care in Bamako, the capital, from the perspective of an Ob/Gyn, which often centers on pregnancy and childbirth. Based on real experiences …

Intellectual Propriety: Compulsory Licenses Through The Trips Agreement And The Doha Declaration On Public Health, Samuel Mintzer Fuchs

Independent Study Project (ISP) Collection

The Agreement on Trade Related Aspects of Intellectual Property (TRIPS), part of the Uruguay Round of trade negotiations led to the creation of the World Trade Organization (WTO) in 1995, has led to a variety of interpretations and opinions. Though its application goes beyond matters of public health, it is this area that has come under the most scrutiny in the last fifteen years as the gaps between developed and developing countries have widened and exposed the health disparities between the two groups. Tensions over intellectual property and access to newly developed medicines to treat diseases such as HIV and …