Medicine and Health Sciences Commons^™

Chinese: Regular Breast Examinations Can Prolong Your Life

Photonovels

Thomas Jefferson University Hospital would like to acknowledge the following community agencies for their assistance in the development of this informational booklet:

Photonovella Participants Grandmother: So King Kong Mother: Huan Qin Ye Daughter: Melody Wong

Chinese American Women’s Sisterhood Society of Philadelphia

Thomas Jefferson University Hospital Chinese Health Information Center

Thomas Jefferson University Hospital Center to Advance Population Health

Supported by a grant from the Philadelphia affiliate of the Susan G. Komen Breast Cancer Foundation, Inc.

Supported by a grant from the Avon Foundation

Chinese Health Information Center 111 South 11th Street Suite 1830 Philadelphia, PA 19107 215-955-8282

Jefferson Alumni Bulletin – Volume 59, Number 2, Spring 2010

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 59, Number 2, Spring 2010

Dean's Message, page 2

Findings: Researchers Decode Powerful Tumor Suppressor, page 4

Jefferson Physicians Respond to Haiti Earthquake, page 6

Student Blog: Exploring Health Care in Uganda, page 10

JHN Physicians Use Robotic System to Examine Patients from Afar, page 13

Crime in the Age of Science: 19th Century Body Snatching, page 14

Faculty Profile: Edouard Trabulsi: Easing the Burden on Cancer Patients, page 18

On Campus, page 20

Class Notes: George Valko, MD ’86: Alumni Association’s New President, page 22

In Memoriam, page 27

By the Numbers, page 29

Resolution Of Clinical Signs Of Ventilator-Associated Pneumonia In Trauma Patients, Kathryn A. Connor, Joseph M. Swanson, Bradley A. Boucher, G. Christopher Wood

Pharmacy Faculty/Staff Publications

Objectives: The ATS/IDSA Ventilator-Associated Pneumonia (VAP) guidelines suggest that clinical improvement of VAP should be apparent within 3–6 days. This study evaluated resolution of clinical signs of VAP in trauma patients after diagnosis.

Methods: Critically injured adults admitted to the trauma intensive care unit (ICU) from June 1, 2006, to December 31, 2007, and subsequently given a diagnosis of VAP were retrospectively assessed. Clinical signs, including derangements of maximum temperature (Tmax), white blood cell (WBC) count, and PaO2/FiO2, were evaluated on days 1–16 after VAP diagnosis. Data are presented as mean ± SD unless otherwise stated. Clinical parameters after VAP …

The Role Of The Ras Superfamily Small G-Proteins In The Proinflammatory Environment Of Rhinovirus-Exposed Monocytic-Lineage Cells, Michael Schreiber

Lawrence University Honors Projects

Rhinoviral infections are a major cause of asthma exacerbations, and though productive rhinovirus infection occurs predominantly in the bronchial epithelial cells of the upper airway, monocytic-lineage cells are implicated in establishing the inflammatory microenvironment observed during rhinoviral asthma exacerbation. It has remained unclear whether small G-protein activation plays a role in establishing this inflammatory microenvironment. The small molecular- weight G-proteins are known to be activated in a variety of cell types upon exposure to a range of viruses. However, it is unclear if small G-protein activation during viral exposure is a byproduct of receptor attachment, is important for viral replication, …

Associative Pattern Mining For Supervised Learning, Harpreet Singh

Doctoral Dissertations

The Internet era has revolutionized computational sciences and automated data collection techniques, made large amounts of previously inaccessible data available and, consequently, broadened the scope of exploratory computing research. As a result, data mining, which is still an emerging field of research, has gained importance because of its ability to analyze and discover previously unknown, hidden, and useful knowledge from these large amounts of data. One aspect of data mining, known as frequent pattern mining, has recently gained importance due to its ability to find associative relationships among the parts of data, thereby aiding a type of supervised learning known …

Pushing Techniques Used By Midwives When Providing Second Stage Labor Care, Kathryn Osborne

Dissertations (1934 -)

A growing body of evidence suggests that spontaneous pushing during the second stage of labor results in better outcomes than directed pushing, which usually involves repeated use of the Valsalva maneuver. However, birth attendants in the United States (U.S.) continue to use directive methods when caring for women in the second stage of labor. This study used quantitative methods with the Theory of Diffusion of Innovations as a framework to identify and describe the practices used by certified nurse-midwives and certified midwives, practicing in the U.S., when caring for women in second stage labor. Data were gathered using a questionnaire …

Hss Departmental Developments Spring 2010, Department Of Health And Sport Sciences

Health and Sport Sciences Newsletter

• Official Recognition of Health Promotion & Fitness
• Alumni Panel Discussion
• Congratulations Grads
• Updates from the Majors

Otterfit News March 2010, Department Of Health And Sport Sciences

Health and Sport Sciences Newsletter

Health, Wellness, & Programming Information for OtterFit participants

Potret Pembangunan Prasarana Kesejahteraan Sosial: Profil Prasarana Pelayanan Kebutuhan Dasar Dan Pembangunan Ekonomi Di 45 Kabupaten/Kota Di Pulau Jawa, Sofyan Cholid

Jurnal Ilmu Kesejahteraan Sosial

No abstract provided.

Range For Normal Body Temperature In Hemodialysis Patients And Its Comparison With That Of Healthy Individuals, Rabia Hasan, Mehreen Adhi, Syed Faisal Mahmood, Fatima Noman, Safia Awan, Fazal Akhtar, Anwar Naqvi, Adeeb Ul Hassan Rizvi

Section of Nephrology

Background/Aims: Patients with chronic kidney disease undergoing hemodialysis have an altered homeostasis leading to altered body temperatures. We aimed to determine the range for normal body temperature in hemodialysis Patients and compared it to healthy individuals. Also, we determined how much axillary temperatures differed from oral temperatures in both groups and whether axillary temperature is affected by the presence of an arteriovenous fistula (AVF) in hemodialysis Patients. Methods: Oral and axillary (left & right) temperatures were recorded using an ordinary mercury-in-glass thermometer in 400 subjects (200 hemodialysis Patients, 200 healthy individuals) at the Sindh Institute of Urology and Transplantation from …

Percutaneous Coronary Intervention In Unprotected Left Main Coronary Artery Disease, Hafeez Ahmed, Javed Majid Tai, Sajid H. Dhakam

Section of Cardiology

Percutaneous coronary intervention for unprotected left main coronary artery disease is potentially an important intervention in surgically unstable patients. A detailed review of medical record and visual analysis of coronary angiography and PCI procedure was undertaken. The study was conducted at the Aga Khan University Hospital, from January 2003 to December 2007. Patients included in the study had unprotected > 70% left main stenosis with ongoing ischemia, considered unsuitable for surgical revascularization. A total of 9 patients were included with a mean age of 70.1 years. Six patients had cardiogenic shock. Eight patients had bifurcation lesion. Simultaneous kissing stenting technique was …

Comparing Modelled Predictions Of Neonatal Mortality Impacts Using List With Observed Results Of Community-Based Intervention Trials In South Asia, Ingrid K. Friberg, Zulfiqar Ahmed Bhutta, Gary L. Darmstadt, Abhay Bang, Simon Cousens, Abdullah H. Baqui, Vishwajeet Kumar, Neff Walker, Joy E. Lawn

Woman and Child Health

Background:There is an increasing body of evidence from trials suggesting that major reductions in neonatal mortality are possible through community-based interventions. Since these trials involve packages of varying content, determining how much of the observed mortality reduction is due to specific interventions is problematic. The Lives Saved Tool (LiST) is designed to facilitate programmatic prioritization by modelling mortality reductions related to increasing coverage of specific interventions which may be combined into packages.
Methods: To assess the validity of LiST outputs, we compared predictions generated by LiST with observed neonatal mortality reductions in trials of packages which met inclusion criteria …

Patient Centered Care Approach To Adherence With Cardiovascular Medications: Self-Determination Theory Integration, David S. Li

Health Services Research Dissertations

Problem statement. Behavioral intervention is used to improve adherence with medication in patients with cardiovascular diseases (CVD), but the effect was not sustainable. Patient-centered care (PCC) as a consumer movement has gained acceptance, but it lacks a theoretical framework. Self-determination theory (SDT) may provide an alternative to improve patients' adherence to chronic cardiovascular medication, as well as a theoretical framework for PCC. Both approaches to CVD management have not been evaluated.

Methods. The study was a quasi-experimental pretest posttest comparison design with consecutive sampling of a hospitalized cardiac patient population. Sixty patients each for the usual care (UC) …

Attitudes And Perceptions Towards Men In Nursing Education, Wally J. Bartfay, Emma Bartfay, Kimberly A. Clow, Terry Wu

Internet Journal of Allied Health Sciences and Practice

Purpose: The aim of the current investigation was to compare and contrast societal perceptions and attitudes towards men in nursing as reported by male and female nursing and non-nursing university students. Methods: A comparative study design was employed to investigate societal attitudes and perceptions towards male nurses enrolled in school of nursing in a mid-sized university in Ontario, Canada. A convenience non-random sampling method was employed that consisted of undergraduate nursing (N = 82) and non-nursing (N = 67) students. Perceptions and attitudes towards men in nursing were assessed using the Attitudes Towards Men in Nursing Scale (ATMINS). Results: Sixty-seven …

Mmp-9/Timp-1 Imbalance Induced In Human Dendritic Cells By Porphyromonas Gingivalis, Ravi Jotwani, Sridhar V K Eswaran, Surinder Moonga, Christopher W Cutler

Faculty, Staff and Student Publications

Matrix metalloproteinase-9 (MMP-9) cleaves collagen, allowing leukocytes to traffic toward the vasculature and the lymphatics. When MMP-9 is unregulated by tissue inhibitor of metalloproteinase-1 (TIMP-1), this can lead to tissue destruction. Dendritic cells (DCs) infiltrate the oral mucosa increasingly in chronic periodontitis, characterized by infection with several pathogens including Porphyromonas gingivalis. In this study, human monocyte-derived DCs were pulsed with different doses of lipopolysaccharide of P. gingivalis 381 and of Escherichia coli type strain 25922, as well as whole live isogenic fimbriae-deficient mutant strains of P. gingivalis 381. Levels of induction of MMP-9 and TIMP-1, as well as interleukin-10 (IL-10), …

Ipecac: A Lesson In Clinical Guidelines, Regina L. Pfister

Internet Journal of Allied Health Sciences and Practice

In 1965, the Food and Drug Administration (FDA) approved the use of ipecac for over-the-counter sale. For years, ipecac remained on the list of “must have” items for households with small children. Typically, Ipecac was used to administer an emetic quickly before reaching the emergency room or to prevent the patient from having to be referred to a medical facility. In 2004, new ipecac guidelines were published stating that the routine stocking and use of ipecac would no longer be recommended. The new guidelines would change what had been accepted for decades. Though Ipecac is no longer suggested for home …

Fleshing Out The Spirit Of Contention: Conflicting Preventative Approaches To The Aids Pandemic In Africa And The Promise Of A Scientific Narrative, Rachel Zimmerman

Honors Capstones

No abstract provided.

Augmentation Of Macular Pigment Following Supplementation With All Three Macular Carotenoids: An Exploratory Study, Eithne Connolly, Stephen Beatty, David Thurnham, James Loughman, Alan Howard, Jim Stack, John Nolan

Articles

Purpose:At the macula, the carotenoids meso-zeaxanthin (MZ), lutein (L), and zeaxanthin (Z) are collectively referred to as macular pigment (MP). This study was designed to measure serum and macular responses to a macular carotenoid formulation. Materials and Methods:Ten subjects were recruited into this study (five normal and five with early age-related macular degeneration [AMD]). Subjects were instructed to consume a formulation containing 7.3mg of MZ, 3.7mg of L, and 0.8mg of Z everyday over an eight-week period. The spatial profile of MP optical density (i.e., MPOD at 0.25°, 0.5°, 1°, and 1.75°) was measured using customized heterochromatic flicker photometry, and …

Professional Product Review Vol. 5 No. 2, American Dental Association, Council On Scientific Affairs

Professional Product Review

A user-friendly newsletter from the ADA Council on Scientific Affairs offering scientifically sound, unbiased, and clinically relevant information to member dentists about professional dental products tested by the ADA. This collection is historical and may not reflect current standards. For up-to-date information contact the ADA.

Chironian Spring/Summer 2010, New York Medical College

The Chironian

No abstract provided.

An Analysis Of Continuous Chest Compression Cpr For Ems Providers During Out Of Hospital Cardiac Arrest, Megan L. Gleason

Honors Projects

A significant amount of research has been done in an attempt to improve the outcomes of patients found in cardiac arrest outside the hospital. The American Heart Association has long advocated Advanced Cardiac Life Support (ACLS), a procedure that encompasses cycles of chest compressions with advanced airway maintenance and defibrillation. Recent evidence has suggested that these current guidelines are ineffective due to prolonged “hands off” time. New research suggests utilizing a technique known as continuous chest compression CPR that delays advanced airway management and instead focuses on defibrillation and continuous chest compressions. Across the country, research has demonstrated that when …

Reliability Measurement Of The Premature Infant Oral Motor Intervention, Clare A. Goebel

Honors Projects

A study was conducted at a Level III Neonatal Intensive Care Unit (NICU) at a large Midwestern teaching medical center to determine the reliability of the Premature Infant Oral Motor Intervention (PIOMI). The PIOMI is a five minute, oral motor intervention using a gloved finger in the mouths of premature infants of at least 29 weeks post-menstrual age (PMA) developed by Dr. Brenda S. Lessen to improve feeding skills in preterm infants. The PIOMI was first introduced in a pilot study done by Dr. Lessen and the results demonstrated a decrease in the amount of time needed for premature infants …

Cerebral Toxoplasmosis In A Patient With Acquired Immunodeficiency Syndrome, Rohana Naqi, Muhammad Azeemuddin, Humera Ahsan

Department of Radiology

Cerebral toxoplasmosis commonly affects patients with advanced HIV immunodeficiency. Toxoplasmosis in patients who are immunocompromised can be severe and debilitating in patients with Central Nervous System (CNS) involvement and the condition may be fatal. We report the case of a 40-year-old man who was a known case of HIV and presented with cerebral toxoplasmosis. His Magnetic Resonance Imaging (MRI) scan showed multiple ring enhancing lesions with extensive surrounding oedema in supratentorial as well as infratentorial region. Lesions were mainly located in the periventricular region as well as at the grey-white matter junction and showed enhancement in the periphery as well …

Oncolog Volume 55, Number 04-05, April-May 2010, John Lebas, Sunni Hoseman

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• IMAGING NERVES: Tetnus Toxin Offers Promise for Neurography
• INBRIEF: Fight-or-Flight Hormones Linked to Metastasis/Drug Combination Shows Promise for Colon Cancer Chemoprevention
• Compass Spring 2010: Early Uterine Papillary Serous Carcinoma: Treatment Options Tailored to Patient and Disease Characteristcs
• House Call: Addressing the Cosmetic Effects of Breast Cancer

Tuberculosis Screening And Treatment Of Latent Tuberculosis Infection Among International College Students, Bhavna Bhardwaj, Eknath Naik, Beata Casanas, Michael D. Breglia, Michael Lauzardo

Florida Public Health Review

Tuberculosis (TB) remains in the crosshairs of many public health policies worldwide that are taking aim at eradicating this potentially curable and preventable illness. Although tuberculosis (TB) incidence has been declining in the United States for over a decade, it still remains a serious public health concern. Currently, there is no public health policy that requires the screening of non-immigrant international university students visiting the United States. Given the rising numbers of visiting international students, this population has come under scrutiny as potential vectors of transmission of TB into the United States. Foreign-born persons from countries with consistently elevated TB …

Community Assessment Of Lead Screening: Health Care Providers In Ada & Elmore Counties, Kayla Anthony, Caitlin Duke, Rn, Jeanette Hinton, Victoria Johnson, Therese Kepner, Natalie Morgan, Jill Rolfson, Ashley Snook, Hannah Tobias

Service-Learning Program

Service Project Purpose: To assess barriers of lead screening among Ada and Elmore Counties Health Care Providers that work with Head Start and Early Head Start children and families and to encourage the use of routine screening methods as part of an early childhood examination regiment through the presentation of available data. Learning Goals: To learn to collaborate with a community agency outside of our discipline. To apply research methods and assessment skills. To utilize community resources as a way of promoting the health of children

Somali Bantu Refugees In Southwest Idaho: Assessment Using Participatory Research, Pamela J. Springer, Mikal Black, Kim Martz, Cathy Marie Deckys, Terri Soelberg

Nursing Faculty Publications and Presentations

Each year, refugees are forced to leave their homes and country due to result of wars or political turmoil. According to the National Office of Refugees, 2.6 million refugees have settled in the United States (U.S.) since 19751. Idaho is a state in which refugees are resettled. The majority of refugees in Idaho are located in the capitol city of Boise. The refugees come from over the globe including Latin America, Europe, Africa and the Middle East.

African refugees represent a unique population in the United States and throughout the world. Many African refugees represent a preliterate population; they have …

Questions And Answers: Bovine Tuberculosis Federal Order

Michigan Bovine Tuberculosis Bibliography and Database

Questions:

What does the Federal Order do?
To whom does the Federal Order apply?
What does the Federal Order mean for me as a producer in an accredited free State/zone?
What does the Federal Order mean for me as a producer in a modified accredited advanced State/ zone?
What does the Federal Order mean for me as a producer in a modified accredited, accreditation preparatory, or nonaccredited State/zone?
What does the Federal Order mean for me as a producer in a modified accredited, accreditation preparatory, or nonaccredited State/zone?
When does the Federal Order take effect?
How long does the Federal …

Delayed Enrichment Of Mesenchymal Cells Promotes Cardiac Lineage And Calcium Transient Development, Liliana Grajales, Jesus Garcia, Kathrin Banach, David Geenen

Peer Reviewed Articles

Bone marrow-derived mesenchymal stem cells (BM-MSCs) can be induced to differentiate into myogenic cells. Despite their potential, previous studies have not been successful in producing a high percentage of cardiac-like cells with a muscle phenotype. We hypothesized that cardiac lineage development in BM-MSC is related to cell passage, culture milieu, and enrichment for specific cell subtypes before and during differentiation. Our study demonstrated that Lin− BM-MSC at an intermediate passage (IP; P8–P12) expressed cardiac troponin T (cTnT) after 21 days in culture. Cardiac TnT expression was similar whether IP cells were differentiated in media containing 5-azacytidine+2% FBS (AZA; 14%) or …

A Gis Analysis Of The Environmental Variables Related To Rift Valley Fever Outbreaks, Jacqueline Florette Jackson

Health Services Research Dissertations

Rift Valley fever is a mosquito-borne disease that causes widespread febrile illness and mortality in domestic animals as well as humans (Gaff, 2007). Rift Valley fever virus was first isolated in 1931 (Daubney, 1931), and since then, outbreaks have occurred in sub-Saharan Africa, southern Africa, Egypt, Saudi Arabia, Yemen and Madagascar, proving it to be a virus able to invade ecologically diverse regions (Gaff, 2007). The potential introduction of Rift Valley fever into the United States suggests the potential for human infection and major economic disruption. It is important to understand the role environmental variables have played in historical outbreaks …