Medicine and Health Sciences Commons^™

Increase In Isolation Of Extended Spectrum Beta Lactamase Producing Multidrug Resistant Non Typhoidal Salmonellae In Pakistan., Kauser Jabeen, Afia Zafar, Seema Irfan, Erum Khan, Vikram Mehraj, Rumina Hasan

Department of Pathology and Laboratory Medicine

Background:Increasing resistance to quinolones and ceftriaxone in non typhoidal Salmonellae is a global concern. Resistance to quinolone and 3rd generation cephalosporin amongst non typhoidal Salmonellae (NTS) from Pakistan has been reported in this study.

Methods:

Retrospective analysis of laboratory data was conducted (1990-2006). NTS were isolated and identified from clinical samples using standard microbiological techniques. Antimicrobial susceptibility testing was performed by Kirby Bauer. Extended spectrum beta lactamase production (ESBL) was detected using combined disc method. Ciprofloxacin sensitivity was detected by nalidixic acid screening method. Minimum inhibitory concentration (MIC) of ciprofloxacin was determined by agar dilution method. Statistical analysis was …

Nonparametric Regression With Missing Outcomes Using Weighted Kernel Estimating Equations, Lu Wang, Andrea Rotnitzky, Xihong Lin

Harvard University Biostatistics Working Paper Series

No abstract provided.

The Influence Of Language Production, Comprehension, And Pragmatic Judgment On Solitary-Passive Withdrawal In Children, Rachel Johnston

Theses and Dissertations

Previous studies examining withdrawal in children with language impairment (LI) have found that these children are more socially withdrawn than their typically developing peers. It seems reasonable to assume that a causal relationship exists between language deficits and withdrawal. However, there is growing evidence that different subtypes of withdrawal have varying social consequences and language may not be closely linked to each subtype. In the present study, subtests from the Comprehensive Assessment of Spoken Language (CASL; Carrow-Woolfolk, 1999) were used to evaluate specific language skills and the Teacher Behavior Rating Scale (TBRS; Hart & Robinson, 1996) was used to evaluate …

Associations Between Sport And Screen-Entertainment With Mental Health Problems In 5-Year-Old Children, Lucy J. Griffiths, Marsha Dowda, Carol Dezateux, Russell R. Pate

Faculty Publications

Background: Few studies have examined the benefits of regular physical activity, and risks of sedentary behavior, in young children. This study investigated associations between participation in sports and screen-entertainment (as components of physical activity and sedentary behavior), and emotional and behavioral problems in this population.

Methods: Cross-sectional analysis of data from 13470 children (50.9% boys) participating in the nationally representative UK Millennium Cohort Study. Time spent participating in sports clubs outside of school, and using screen-entertainment, was reported by the child's mother at child age 5 years, when mental health was also measured using the Strengths and Difficulties Questionnaire.

Results …

Genetic Variations Of Cyp2b6 Enzyme And The Response To Meperidine In Oral Sedation, Heath Whitfield

Theses and Dissertations

Purpose: The purpose of this study was to determine the relationship of the CYP2B6 genotype to the clinical response to meperidine in pediatric dental patients. Methods: Forty-nine patients, ASA I/ II, 41–101 months old, received an oral sedative regimen containing meperidine for dental treatment. The North Carolina Behavior Rating Scale (NCBRS) and Overall Effectiveness of Sedation Scale (OESS) were used to assess their behavior and sedation outcome. Saliva DNA samples were genotyped by PCR-RFLP. Results: We found the following genotype distributions: homozygous wild-type 1*1 (n = 19, 39%), heterozygous 1*6 (n = 25, 51%), and homozygous variant 6*6 (n = …

The Effects Of Motivational Interviewing In Pregnancy On Knowledge And Retention Of Infant Oral Health Information, Andrew Zima

Theses and Dissertations

THE EFFECTS OF MOTIVATIONAL INTERVIEWING IN PREGNANCY ON KNOWLEDGE AND RETENTION OF INFANT ORAL HEALTH INFORMATION By Andrew D. Zima, Jr., B.S., M.S., D.D.S. A thesis submitted in partial fulfillment of the requirements for the degree of Masters of Science in Dentistry at Virginia Commonwealth University. Virginia Commonwealth University, 2010 Major Director: Tegwyn H. Brickhouse, D.D.S., Ph.D Associate Professor, Department of Pediatric Dentistry Purpose: The purpose was to examine the effect of motivational counseling in pregnancy with readiness and acceptance of infant oral health information. Methods: The study used a prospective cohort design to examine the effect of prenatal education …

Differential Roles Of The Two Major Endocannabinoid Hydrolyzing Enzymes In Cannabinoid Receptor Tolerance And Somatic Withdrawal, Joel Schlosburg

Theses and Dissertations

While there is currently active debate over possible therapeutic applications of marijuana and cannabis-based compounds, consistently their primary drawbacks have been the psychoactive properties, dependence, and abuse potential. Prolonged administration of ∆9-tetrahydrocannabinol (THC), the primary psychoactive constituent in marijuana, demonstrates both tolerance and physical withdrawal in both preclinical and clinical studies. Repeated THC administration also produces CB1 receptor adaptations in the form of reduced activation of receptors, along with a downregulation of membrane surface receptors, in many brain regions involved in THC-associated behaviors. The increased need for drug to maintain therapeutic effects, and a withdrawal syndrome following discontinuation of use, …

The Eternal Flame: Politics Of The Olympic Games, Alyssa Gunstrom

Honors Capstones

Capstone submitted as a graduation requirement for the BSU Honors Program.

Optimal Bone Strength And Mineralization Requires The Type 2 Iodothyronine Deiodinase In Osteoblasts, J. H. D. Bassett, Alan Boyde, Peter G. T. Howell, Richard H. Bassett, Thomas M. Galliford, Marta Archanco, Holly Evans, Michelle A. Lawson, Peter Croucher, Donald L. St. Germain, Valerie A. Galton, Graham R. Williams

Dartmouth Scholarship

Hypothyroidism and thyrotoxicosis are each associated with an increased risk of fracture. Although thyroxine (T4) is the predominant circulating thyroid hormone, target cell responses are determined by local intracellular availability of the active hormone 3,5,3'-L-triiodothyronine (T3), which is generated from T4 by the type 2 deiodinase enzyme (D2). To investigate the role of locally produced T3 in bone, we characterized mice deficient in D2 (D2KO) in which the serum T3 level is normal. Bones from adult D2KO mice have reduced toughness and are brittle, displaying an increased susceptibility to fracture. This phenotype is characterized by a 50% reduction in bone …

Ada News - 04/19/2010, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Proteasome-Dependent Entry Of Herpes Simplex Virus, Mark Delboy

Theses and Dissertations

Herpes simplex virus entry into cells is a multistep process that engages the host cell machinery. The proteasome is a large, ATP-dependent, multisubunit protease that plays a critical role in the maintenance of cell homeostasis. A battery of assays were used to demonstrate that proteasome inhibitors blocked an early step in herpes simplex virus entry that occurred after capsid penetration into the cytosol but prior to capsid arrival at the nuclear periphery. Proteasome-dependent viral entry was not reliant on host or viral protein synthesis. MG132, a peptide aldehyde that competitively inhibits the degradative activity of the proteasome, had a reversible …

Sensitivity Analysis – The Effects Of Glasgow Outcome Scale Misclassification On Traumatic Brain Injury Clinical Trials, Juan Lu

Theses and Dissertations

I. EFFECTS OF GLASGOW OUTCOME SCALE MISCLASSIFICATION ON TRAUMATIC BRAIN INJURY CLINICAL TRIALS The Glasgow Outcome Scale (GOS) is the primary endpoint for efficacy analysis of clinical trials in traumatic brain injury (TBI). Accurate and consistent assessment of outcome after TBI is essential to the evaluation of treatment results, particularly in the context of multicenter studies and trials. The inconsistent measurement or interobserver variation on GOS outcome, or for that matter, on any outcome scales, may adversely affect the sensitivity to detect treatment effects in clinical trial. The objective of this study is to examine effects of nondifferential misclassification of …

Medical School Watercooler Newsletter - April 18, 2010, Lindsey Lyle

Watercooler Newsletter

This is the April 18, 2010 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

• Dr. Anne Cross to Present Lectures on Multiple Sclerosis
• USA Awarded $7.5 Million Grant To Lead Alabama's Effort To Improve Health Care Through Electronic Medical Records
• USA Cardiology Granted Accreditation for Nuclear Stress Testing
• Walter Beckham Retirement Reception
• "The Mitochondrial Paradigm for Disease Susceptibility: Prehistoric Events Influencing Contemporary Disease Risk"

Norris, Ruby (Fa 218), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid and full-text scan of collection (Click on “Additional Files” below) for Folklife Archives Project 218. Paper: "[Folk Medicine in Cumberland County]" written by Ruby Norris for a Western Kentucky University folk studies class.

The Point Of No Return, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Celebrate Nursing, Celebrate Gold: 50th Anniversary Of The Illinois Wesleyan University School Of Nursing Bsn, School Of Nursing, Illinois Wesleyan University

History

No abstract provided.

The Role For Osmotic Agents In Children With Acute Encephalopathies: A Systematic Review, Samson Gwer, Hellen Gatakaa, Leah Mwai, Richard Idro, Charles R. Newton

All Peer-Reviewed Publications

Background: Raised intracranial pressure (ICP) is known to complicate both traumatic and non-traumatic encephalopathies. It impairs cerebral perfusion and may cause death due to global ischaemia and intracranial herniation. Osmotic agents are widely used to control ICP. In children, guidelines for their use are mainly guided by adult studies. We conducted this review to determine the current evidence of the effectiveness of osmotic agents and their effect on resolution of coma and outcome in children with acute encephalopathy.Methods: We searched several databases for published and unpublished studies in English and French languages, between January 1966 and March 2009. We considered …

Synthesis Of An Endothelial Cell Mimicking Surface Containing Thrombomodulin And Endothelial Protein C Receptor, Karl E. Kador

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Synthetic materials for use in blood contacting applications have been studied for many years with limited success. One of the main areas of need for these materials is the design of synthetic vascular grafts for use in the hundreds of thousands of patients who have coronary artery bypass grafting, many without suitable veins for autologous grafts. The design of these grafts is constrained by two common modes of failure, the formation of intimal hyperplasia (IH) and thrombosis. IH formation has been previously linked to a mismatching of the mechanical properties of the graft and has been overcome by creating grafts …

Today - April 16, 2010, Loma Linda University

TODAY

Inside this issue:

-- Behavior Health Institute hosts opening ceremonies
-- LLU students travel to the Amazon
-- LLU School of Pharmacy students provide blood pressure screening and medication consultation during National Patient Safety Week
-- School of Public Health alumnus provides holistic healing for torture survivors in San Diego
-- Visiting Japanese students learn about respiratory care
-- LLU students receive scholarships during the 26th BALL Scholarship Banquet
-- Pediatric Wholistic Medicine Clinic to hold open house in new location
-- Vaneta Condon: A 52-year journey dedicated to the success of students
-- Board of Trustees report
-- School …

Wright State University Celebration Of Research, Scholarship And Creative Activities 2010 Book Of Abstracts, Wright State University Office Of Undergraduate Research And Stemm Activities

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's inaugural Celebration of Research, Scholarship and Creative Activities on April 16, 2010.

The Influence Of Organizational Culture On The Existence Of Systems Employed To Improve Quality Of Care In Medical Office Practices, Donna Dugan

Theses and Dissertations

A frequently cited reason for poor quality of care in the ambulatory care setting is the lack of optimally designed systems to address care for those with preventive or chronic care needs. Organizational theory suggests that culture plays an important role in the shaping of these types of programs. The purpose of this cross-sectional study is to understand through descriptive and regression analysis of secondary data, the relationship between the existence of cultural characteristics such as collegiality, quality emphasis and autonomy, and the systems employed to improve quality of care within primary care practices. The study uses an integrated theoretical …

Neuroprotection With Anesthetics In Two Models Of Cerebral Ischemia, Rafael Eduardo Chaparro Buitrago

USF Tampa Graduate Theses and Dissertations

Neuroprotection with anesthetics has been studied for many decades; important advances in this field have modified the way Anesthesiologists treat patients in the operating room. Animal models have played an important role in the study of ischemia in the operating room. Recent studies have demonstrated that the effect of anesthetics seems to be different in different animal models. We decided to evaluate anesthetics in a well-known model of cerebral ischemia and also in hypotensive models designed by us. We used a model of cerebral ischemia (MCAO) to test anesthetics neuroprotective effect in a two-week period. Then, we used a model …

Deaths In Custody In Nevada, 2001-2006, Brian R. Brehman, Terance D. Miethe, Timothy C. Hart

Graduate Research Symposium (2010 - 2017)

A large number of prisoners die each year while under the custody of the state. These deaths include prisoners who are executed under state laws and other deaths in custody from a variety of causes. Nationally, 18,550 individuals died in the custody of a state prison between 2001 and 2006. This state data brief examines deaths in custody in Nevada prisons and jails and compares them to national averages. This report summarizes the prevalence rates for deaths in custody, changes in these custody deaths over time, the cause of these deaths, and compares custody deaths in Clark County jail to …

Evaluating The Comprehensiveness Of Youth Access To Tobacco Legislation, Richard Clark

Graduate Research Symposium (2010 - 2017)

The deadly effects of smoking have been well documented since the 1960s. As laws and ordinances have been instituted at the state level, various measures have been developed in an attempt to measure both the comprehensiveness and effectiveness of such restrictions. This paper seeks to build on the rating systems already developed that currently look at individual laws by developing an overall rating scale of state level smoking restrictions and their effectiveness over time. Results of the overall rating scale will be shared along with recommendations for future research.

Therapeutic Alliance And Client Satisfaction From The Client’S Perspective, Colleen Peterson, Armeda Stevenson, Katherine M. Hertlein, Stephen Fife

Graduate Research Symposium (2010 - 2017)

This was the second phase of a two phase mixed methodology study. Presented is the qualitative portion consisting of semi-structured phone interviews conducted with past clients in order to examine the relationship of the therapeutic alliance and client satisfaction with client retention and termination status.Findings were classified into three main categories: therapist characteristics, treatment structural characteristics and process characteristics.

Defining Intimacy In Diverse Asian Cultures, Blendine Hawkins, Katherine Herlein

Graduate Research Symposium (2010 - 2017)

America has continued to diversify as a nation, welcoming people from every race, culture and continent. The US Census Bureau (2004) reported that there were 13.5 million Asians in America and these numbers are increasing (US Census Bureau, 2004). This indicates that there is a greater demand for competent and effective mental health care to meet the needs of this heterogeneous group. Asian Americans can be best helped by a therapist who is sensitive, knowledgeable and has an understanding about the core values which are present in many Asian cultures. There are limited resources and treatment guides for this population …

The Portrayal Of Schizophrenia In Television: An Experiment Assessing How Viewer Attitudes Are Affected, Lindsey Jo Hand, Paul Traudt

Graduate Research Symposium (2010 - 2017)

Portrayals of schizophrenia in the media have been found to be very negative in nature. This study is an attempt to take research in this area a step further by conducting an experiment measuring attitudes of viewers toward schizophrenia before and after viewing an episode of Law and Order: Special Victims Unit in which a man with schizophrenia is depicted as a dangerous sexual deviant. Participants were given a pretest, viewed the television show and then were given a post-test. The post-test and pretest are identical and consist of questions from the Community Attitudes on Mental Illness (CAMI) scale and …

News In Brief

Jefferson Surgical Solutions

No abstract provided.

Jefferson Awards Gala Celebrates A Dedicated Faculty Member

Jefferson Surgical Solutions

No abstract provided.

On The Job-Katie Ashburn, Crnp, And Shawn Pierce, Cnrp

Jefferson Surgical Solutions

No abstract provided.