Medicine and Health Sciences Commons^™

W. Beaumont [Jefferson Barracks, Mo] To Joseph Lovell, Surgeon General [Washington, Dc] Regarding: Hopes To Employ St. Martin And To Continue Observations And Experiments, Preference For Posts More Centrally Located And Conducive To Research Work, And Request For Furlough. September 6, 1834

1834

No abstract provided.

W. Beaumont [Jefferson Barracks, Mo] Regarding: Request For Furlough For Family Reasons. September 6, 1834

1834

No abstract provided.

W. Beaumont Jefferson Barracks, Mo] Regarding: Inventories Of Effects Of Two Dead Soldiers, William Telford And Corporal Jones. October 25, 1834

1834

No abstract provided.

S. Cooper [Jefferson Barracks, Saint Louis, Mo] To W. Beaumont, Regarding: Transfer To Fort Crawford, Transfer Of Finley To Jefferson Barracks. October 1, 1834. W. Beaumont [Jefferson Barracks, Mo] To Joseph Lovell, Surgeon General’S Office [Washington, Dc] Regarding: Finley’S Desertion. October 1, 1834

1834

No abstract provided.

W. Beaumont [Jefferson Barracks, Mo] To Joseph Lovell, Surgeon General [Washington, Dc] Regarding: Request For Transfer Of Samuel G. I. Decamp To Jefferson Barracks Instead Of Finley. October 20, 1834

1834

No abstract provided.

Joseph Lovell, Surgeon General’S Office [Washington, Dc] To W. Beaumont [Jefferson Barracks, Mo] Regarding: Finley Ordered To Jefferson Barracks To Await Trial With W. Beaumont As Witness. October 21, 1834

1834

No abstract provided.

Lieutenant Potter To W. Beaumont, Requesting Clarification Of Latter’S Orders. 1834

1834

No abstract provided.

Joseph Lovell, Surgeon General’S Office [Washington, Dc] To W. Beaumont [Plattsburgh, Ny] Regarding: Vaccine Supply Sent And Official Notice Of Transfer To Jefferson Barracks. December 26, 1834

1834

No abstract provided.

S. Highley, [London, England] To Thomas P. Jones [Washington, Dc] Regarding: Declining Offer To Publish Experiments And Observations And Return Of Manuscript. February 20, 1834

1834

No abstract provided.

Notes On “Review Of Beaumont On The Gastric Juices” (Experiments And Observations) In The Western Medical Gazette Of Cincinnati, May 1834

1834

No abstract provided.

Memo, Draft Memorial, W. Beaumont To Congress, With Narrative Of Experiments On St. Martin And Expenses Incurred. 1834

1834

No abstract provided.

W. Beaumont [Washington, Dc] To Deborah Beaumont [Plattsburgh, Ny] Regarding: Travels By Boat And Stage From Louisville Over The Allegheny Mountains To Virginia. November 15, 1834

1834

No abstract provided.

A Secondary Data Analysis Of The Practice Intervention Designed To "Wipe Out C. Difficile", Kimberly Aronhalt

Theses and Graduate Projects

Clostridium dfficile infection (CDI) recognized as a global healthcare-associated infection (HAI) causing infectious diarrhea, has increased in incidence, severity, and mortality among patients in the last three decades. Related health care costs to patients and health care facilities are enormous. To prevent HAIs healthcare organizations are charged to have infection prevention control programs in place to address CDI. Surveillance of CDI and prevention strategies are challenged to impact the transmission of CDI due to its anaerobic, spore forming characteristics. At a tertiary medical center, Wipe Out C. dfficile was a targeted approach for five high incident units to reduce CDI. …

Selective Lesions Of Medial Septal Gabaergic Neurons Disrupt Hippocampal Theta Rhythm Amplitude, Miriam G. Perez-Cordova, Saul Jaime, Herminio M. Guajardo, Luis V. Colom

Health & Biomedical Sciences Faculty Publications

Septal inputs critically modulate hippocampal function. However, the role of Medial Septal/Diagonal Band (MS/DB) neuronal populations in hippocampal theta rhythm generation is still under debate. MS/DB GABAergic neurons selectively innervate inhibitory hippocampal interneurons and through this action exert a powerful control on hippocampal excitability. To further investigate the role of the MS/DB GABAergic neurons in hippocampal theta rhythm generation, the antibody Gamma amino butyric acid Transporter 1 (GAT-1) conjugated to saporin (SAP, 3µL at 325ng/µL) was injected in the MS/DB of adults Sprague Dawley rats to selectively destroy GABAergic neurons. Population estimates of MS/DB GABAergic neurons were analyzed using StereoInvestigator …

Bioactive Peptide-Based Probes, Clair D. Hicks, Peter A. Crooks

Pharmaceutical Sciences Faculty Patents

A method for preparing a site-specific peptide probe, wherein the peptide is specific to a receptor, includes modifying a marker to include a tether molecule and covalently binding the tether molecule to the peptide. The present invention also provides a labeled probe, comprising a peptide specific for a receptor and a marker. The marker is modified to include a tether molecule capable of covalently binding to the peptide. The peptide is typically derived from a bacteriophage or is a synthetic analog or derivative of the peptide. The receptor will typically be found on a surface of a bacterial cell. The …

The Development And Use Of A Geographic Information System For Evaluating The Association Between Pesticide Exposure And Prostate Cancer, Kristen Wells

Theses and Dissertations

Abstract 1 – A Geographic Information System for Evaluating Residential Pesticide Exposure and Prostate Cancer Incidence Agricultural pesticide exposure is hypothesized to be a risk factor for prostate cancer, and such exposures are of particular concern for men living in farming communities where large-scale pesticide applications occur. Prostate cancer incidence data were obtained from the State Health Registry of Iowa for the years 1996 through 2006, and county and census tract level age-adjusted incidence rates were calculated. Historical crop-specific land use records and pesticide sales data for the state of Iowa during 1990 were integrated into a geographic information system …

The Transcriptional Regulation Of Hla-E By Interferon-Gamma In Tumor Cells, Quintesia Grant

Theses and Dissertations

The human Class Ib gene, HLA-E inhibits both Natural Killer Cells and a subset of CD8+ cytotoxic T lymphocytes by engaging the CD94/NKG2A inhibitory receptor. IFN-γ induces the expression of HLA-E as well as Class Ia molecules, which are required for the killing of target cells. Since HLA-E has negative effects on immune killing of target cells, we have sought to identify locus specific mechanisms of IFN-γ induction in order to identify molecular targets for selective activation of Class Ia genes, but not HLA-E. We have previously identified a unique upstream IFN-γ response region in the HLA-E promoter and showed …

Effectiveness Of Counseling For Anxiety And Depression In Mothers Of Children Ages 0-30 Months By Community Workers In Karachi, Pakistan: A Quasi Experimental Study, Niloufer Sultan Ali, Badar S. Ali, Iqbal Azam Syed, Ali Khan Khuwaja

Department of Family Medicine

Background: The prevalence of anxiety/depression is quite high during the perinatal period but unfortunately its detection and treatment have been less than satisfactory. Moreover, many women are reluctant to take pharmacotherapy for fear of excretion of drugs into their breast milk. This study assesses the effectiveness of counseling from minimally trained community health workers in reducing anxiety/depression, the rate of recurrence and the interval preceding recurrence in women during first two and a half years after childbirth.
Methods: In a quasi-experimental study, community women from two under-privileged communities were trained in data gathering, teaching healthy child-rearing practices, basic counseling skills, …

Characterizing Accuracy Of Total Hemoglobin Recovery Using Contrast-Detail Analysis In 3d Image-Guided Near Infrared Spectroscopy With The Boundary Element Method, Hamid R. Ghadyani, Subhadra Srinivasan, Brian W. Pogue, Keith D. Paulsen

Dartmouth Scholarship

The quantification of total hemoglobin concentration (HbT) obtained from multi-modality image-guided near infrared spectroscopy (IG-NIRS) was characterized using the boundary element method (BEM) for 3D image reconstruction. Multi-modality IG-NIRS systems use a priori information to guide the reconstruction process. While this has been shown to improve resolution, the effect on quantitative accuracy is unclear. Here, through systematic contrast-detail analysis, the fidelity of IG-NIRS in quantifying HbT was examined using 3D simulations. These simulations show that HbT could be recovered for medium sized (20mm in 100mm total diameter) spherical inclusions with an average error of 15%, for the physiologically …

Pyridoxal Kinase: Its Role In Vitamin B6 Metabolism, Jigarkumar Desai

Theses and Dissertations

Pyridoxal kinase (PL kinase) and pyridoxine 5’-phosphate oxidase (PNP oxidase) are the two vitamin B6 salvage enzymes involved in metabolism of the primary inactive vitamin B6 (pyridoxal, pyridoxine and pyridoxamine) into the active cofactor form, pyridoxal 5’-phosphate (PLP). PLP, arguably the most important vitamin, is required by numerous vitamin B6 (PLP-dependent) enzymes as a co-factor. These enzymes serve vital roles in the metabolism of glucose, lipids, amino acids, heme, DNA/RNA and many neurotransmitters. High levels of vitamin B6 are linked to neurotoxicity, due to the non-specific interactions of PLP with non-B6 proteins. This problem is controlled, in part, by maintaining …

Medical School Watercooler Newsletter - July 18, 2010, Lindsey Lyle

Watercooler Newsletter

This is the July 18, 2010 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Med School Café - Expert Advice For The Community
• College of Medicine Welcomes Dr. Ian Malcolm
• Mark Your Calendar

Draft Of Letter From W. Beaumont [Saint Louis, Mo] To Ramsey Crooks, Regarding: Attempt To Employ St. Martin Through Crooks. January 23, 1839

1839

No abstract provided.

William B. Lewis, Second Auditor’S Office, Treasury Department [Washington, Dc] To W. Beaumont [Saint Louis, Mo] Regarding: Returns Of Hospital And Medical Stores Of September 30, 1837 Received. February 20, 1839

1839

No abstract provided.

Draft Of Letter From W. Beaumont [Saint Louis, Mo] To Joseph H. Lamotte Regarding: Advice To Lamotte Concerning Sarah Beaumont. February 21, 1839

1839

No abstract provided.

Thomas Lawson, Surgeon General [Washington, Dc] To W. Beaumont [Saint Louis, Mo] Regarding: Received Weather Diary, Accounts, Reports Of Sick And Of Recruits Examined. March 7, 1839

1839

No abstract provided.

J.B. Mcdowell [Saint Louis, Mo] To W. Beaumont, Regarding: Mcdowell’S Proposal Of Medical Partnership. March 13, 1839

1839

No abstract provided.

N.R. Smith [Lexington, Ky] To W. Beaumont [Saint Louis, Mo] Regarding: Letter Of Introduction For Thomas Reyburn. March 12, 1839

1839

No abstract provided.

Wills Dehass [Saint Louis, Mo] To W. Beaumont, Regarding: Medical Partnership Proposal. March 15, 1839

1839

No abstract provided.

William Combe [Albany, Ny] To W. Beaumont [Saint Louis, Mo] Regarding: A Copy Of W. Beaumont’S Work On Digestion Republished In Great Britain By Andrew Combe. March 18, 1839

1839

No abstract provided.

Thomas Lawson, Surgeon General [Washington, Dc] To W. Beaumont [Saint Louis, Mo] Regarding: Request For Leave Of Absence Denied Unless Beaumont Pays Replacement. March 27, 1839

1839

No abstract provided.