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Articles 1561 - 1590 of 5702
Full-Text Articles in Medicine and Health Sciences
Draft Of Letter From W. Beaumont [Saint Louis, Mo] To Second Auditor’S Office, Regarding: Disputes Disallowed Payment For Forage From Accounts Of A. Massias. April 20, 1840
1840
No abstract provided.
W. Beaumont, Inaugural Address As The President Of The Saint Louis Medical Society, May 1840
W. Beaumont, Inaugural Address As The President Of The Saint Louis Medical Society, May 1840
1840
No abstract provided.
Deltanp63 Transcriptionally Regulates Atm To Control P53 Serine-15 Phosphorylation., Ashley L. Craig, Jitka Holcakova, Lee E. Finlan, Marta Nekulova, Roman Hrstka, Nuri Gueven, James Direnzo, Graeme Smith, Ted R. Hupp, Borivoj Vojtesek
Deltanp63 Transcriptionally Regulates Atm To Control P53 Serine-15 Phosphorylation., Ashley L. Craig, Jitka Holcakova, Lee E. Finlan, Marta Nekulova, Roman Hrstka, Nuri Gueven, James Direnzo, Graeme Smith, Ted R. Hupp, Borivoj Vojtesek
Dartmouth Scholarship
Background: ΔNp63α is an epithelial progenitor cell marker that maintains epidermal stem cell self-renewal capacity. Previous studies revealed that UV-dam age induced p53 phosphorylation is confined to ΔNp63α-positive cells in the basal layer of human epithelium. Results: We now report that phosphorylatio n of the p53 tumour suppressor is po sitively regulated by ΔNp63α in immortalised human keratinocytes. ΔNp63α depletion by RNAi reduces steady-state ATM mRNA and protein levels, and attenuates p53 Serine-15 phosphorylation. Conversely, ectopic expression of ΔNp63α in p63-null tumour cells stimulates ATM transcription and p53 Seri ne-15 phosphorylation. We show that AT M is a …
Role Of Pyridoxine 5'-Phosphate Oxidase In Metabolism And Transfer Of Pyridoxal 5'-Phosphate, Sayali Karve
Role Of Pyridoxine 5'-Phosphate Oxidase In Metabolism And Transfer Of Pyridoxal 5'-Phosphate, Sayali Karve
Theses and Dissertations
Deficiency of vitamin B6 due to mutations in key B6 metabolizing enzymes is suspected to contribute to several pathologies. Vitamin B6 in its active form, pyridoxal 5’-phosphate (PLP) is a cofactor for over 140 known B6 requiring (or PLP-dependent) enzymes, that serve vital roles in many biochemical reactions. There are three primary vitamin B6 forms, pyridoxine (PN), pyridoxamine (PM) and pyridoxal (PL) which are phosphorylated to pyridoxine 5’-phosphate (PNP), pyridoxamine 5’-phosphate (PMP) and PLP respectively. Pyridoxal kinase (PLK) and pyridoxine 5’-phosphate oxidase (PNPO) are the key enzymes involved in both salvage and de novo pathways of PLP biosynthesis. Mutations in …
The Effect Of Anticholinergic Burden On Functional Outcomes In Patients With Moderate To Severe Alzheimer’S Disease, Sheetal Dharia
The Effect Of Anticholinergic Burden On Functional Outcomes In Patients With Moderate To Severe Alzheimer’S Disease, Sheetal Dharia
Theses and Dissertations
Background: Alzheimer’s disease (AD) is the most common form of dementia and is characterized by a progressive loss of memory, judgment, and thinking in older adults. The current treatment is cholinesterase inhibitors, which increase acetylcholine at the synapse. Medications with anticholinergic (AC) activity are given for a variety reasons including for the treatment of comorbid conditions or side effects of cholinesterase inhibitors (ChEIs). These drugs inhibit acetylcholine in the brain. Studies have shown the detrimental outcomes of using AC medications with ChEIs in older adults. Moreover, older patients take more medications and have an increased risk of developing AC toxicity …
Combined Hip Arthroscopy And Limited Open Osteochondroplasty For Anterior Femoroacetabular Impingement, John C. Clohisy, Lukas P. Zebala, Jeffrey J. Nepple, Gail Pashos
Combined Hip Arthroscopy And Limited Open Osteochondroplasty For Anterior Femoroacetabular Impingement, John C. Clohisy, Lukas P. Zebala, Jeffrey J. Nepple, Gail Pashos
Open Access Publications
No abstract provided.
Martin Van Buren, Vice President Of The United States [Washington, Dc] To W. Beaumont, Regarding: Thanks For Experiments And Observations. January 1, 1834
1834
No abstract provided.
Thomas Henderson To W. Beaumont, U. S. Army [Fuller’S Boarding House, Washington, Dc] Regarding: Thanks And Praise For Experiments And Observations. January 8, 1834
1834
No abstract provided.
Thomas Sewall, Chairman Of The Committee Of The U. S. Senate [Washington, Dc] To Asher Robbins, With Attached Note By Joseph Lovell To Asher Robbins, Regarding: Their Favorable Opinion Of Experiments And Observations And Beaumont’S Memorial To Congress For Ongoing Expenses Of This Work. January 20, 1834
1834
No abstract provided.
Franklin Bache [Philadelphia, Pa] To W. Beaumont, Surgeon, U. S. Army [Washington, Dc] Regarding: Advice From Bache On Memorial To Congress. January 24, 1834
1834
No abstract provided.
Robert M. Johnson [Washington, Dc] To W. Beaumont, Army [Washington, Dc] Regarding: Thanks For Experiments And Observations. January 21, 1834
1834
No abstract provided.
Mr. Binney [Washington, Dc] To W. Beaumont, Regarding: Thanks For Experiments And Observations. January 24, 1834
1834
No abstract provided.
Robley Dunglison, Professor Of Materia Medica, Therapeutics, Hygiene And Medical Jurisprudence [University Of Maryland, Baltimore] To Senator Asher Robbins [Washington, Dc] In Support Of The Memorial To Congress. January 25, 1834
1834
No abstract provided.
James T. Cromwell, M.D., Secretary Of The Medical Society Of The City And County Of New York, To Samuel Beaumont [Plattsburgh, Ny] Requesting W. Beaumont’S Address. January 26, 1834
1834
No abstract provided.
Aaron Ward [Washington, Dc] To W. Beaumont, Surgeon To The U. S. Army [Washington, Dc] Regarding: Thanks And Praise For Experiments And Observations. January 26, 1834
1834
No abstract provided.
R. H. Wilde To W. Beaumont, Regarding: Thanks And Praise For Experiments And Observations. January 27, 1834
1834
No abstract provided.
Thomas H. Benton, U. S. Senate [Washington, Dc] To W. Beaumont [Washington, Dc] Regarding: Thanks For Experiments And Observations. January 28, 1834
1834
No abstract provided.
S. Beardsley, Surgeon, U. S. Army [Washington, Dc] To W. Beaumont Regarding: Thanks For Experiments And Observations. January 28, 1834
1834
No abstract provided.
D. Wardwell, U.S. House Of Representatives [Washington, Dc] To W. Beaumont, Surgeon, U. S. Army, Regarding: Thanks And Praise For Experiments And Observations. January 28, 1834
1834
No abstract provided.
W. Beaumont, Memo Preparatory To Drafting Memorial To Congress Requesting Reimbursement For Experiments. 1834
1834
No abstract provided.
Edward Everett [Washington, Dc] To W. Beaumont, Regarding: Thanks For Experiments And Observations. February 4, 1834
1834
No abstract provided.
Thomas Henderson [Washington, Dc] To Senator Asher Robbins Regarding: Endorsing W. Beaumont’S Memorial To Congress. February 10, 1834
1834
No abstract provided.
P. C. Fuller [Washington, Dc] To W. Beaumont Regarding: Thanks And Praise For Experiments And Observations. February 5, 1834
1834
No abstract provided.
Abel Huntington, John Thompson, And Robert Mitchell, House Of Representatives [Washington, Dc] To James M. Wayne Of The Library Committee Regarding: Endorsement Of The Memorial To Congress And Suggested Purchase Of Experiments And Observations For The Library Of Congress, Department Of The Army, And Department Of The Navy. February 11, 1834
1834
No abstract provided.
F. Whittlesey, House Of Representatives [Washington, Dc] To W. Beaumont [Washington, Dc] Regarding: Thanks For Experiments And Observations. February 14, 1834
1834
No abstract provided.
Henry Renshaw [London, England] To W. Miller Regarding: Declining Offer To Reprint Experiments And Observations. February 24, 1834
1834
No abstract provided.
A. Vail [London, England] To W. Beaumont, Regarding: Failure To Secure A European Publisher For Experiments And Observations. March 2, 1834
1834
No abstract provided.
Special Order From R. Jones, Adjutant General’S Office [Washington, Dc] Regarding: W. Beaumont’S Assignment To Medical Board. March 4, 1834
1834
No abstract provided.
Minutes Of Army Medical Board [Washington, Dc] By W. Beaumont, Member And Recorder, Regarding: Examination Of Rives And Clement A. Finley As Candidates For The Army Medical Staff. March 5, 1834–March 7, 1834
1834
No abstract provided.
Draft Of Minutes Of Army Medical Board [Washington, Dc] By W. Beaumont, Member And Recorder, Regarding: Examination Of Rives And Clement A. Finley As Candidates For The Army Medical Staff. March 5, 1834–March 7, 1834
1834
No abstract provided.