Medicine and Health Sciences Commons^™

Bridging The Care Continuum: Patient Information Needs For Specialist Referrals., Carol L. Ireson, Svetla Slavova, Carol L. Steltenkamp, F. Douglas Scutchfield

Preventive Medicine and Environmental Health Faculty Publications

BACKGROUND: Information transfer is critical in the primary care to specialist referral process and has been examined extensively in the US and other countries, yet there has been little attention to the patient's perspective of the information transfer process. This cross-sectional study examined the quality of the information received by patients with a chronic condition from the referring and specialist physician in the specialist referral process and the relationship of the quality of information received to trust in the physicians.

METHODS: Structured telephone interviews were conducted with a random sample of 250 patients who had experienced a referral to a …

The Otto Aufranc Award Identification Of A 4 Mb Region On Chromosome 17q21 Linked To Developmental Dysplasia Of The Hip In One 18-Member, Multigeneration Family, George Feldman, Chelsea Dalsey, Kasia Fertala, David Azimi, Paolo Fortina, Marcella Devoto, Maurizio Pacifici, Javad Parvizi

Department of Orthopaedic Surgery Faculty Papers

Developmental dysplasia of the hip (DDH) is a disabling condition of the hip that, depending on geography, can afflict between 20-80% of patients with end-stage arthritis of the hip. Despite its prevalence, the etiology of this disease remains unknown. DDH is a complex disorder with both environmental and genetic causes.. Based on the literature, the candidate genes for the disease are HOXB9, collagen type I α1, and DLX 3. The purpose of our study was to map and characterize the gene or genes responsible for this disorder by family linkage analysis. We recruited one 18-member, multigeneration affected family to provide …

Therapeutic Strategies Aimed To Facilitate Axonal Regeneration And Functional Recovery Following Traumatic Spinal Cord Injury, Woon Chow

Theses and Dissertations

Traumatic spinal cord injury (SCI) is a physically debilitating, emotionally devastating, financially costly, and life-changing condition that afflicts more than 1,000,000 people in the United States alone. Owing to the characteristic neuropathology and low regenerative capacity of the central nervous system, many victims of SCI are left permanently paralyzed. Though the tissue damage caused by the initial insult almost certainly cannot be reversed, intensive research in recent years to elucidate the cellular and molecular events that follows has provided new grounds for optimism. Accordingly, in this dissertation, we present a number of potential treatment strategies aimed to address some of …

Baseline Predictors Of Virological Response For Chronic Hepatitis B Patients, Xue-Jie Wu, Yan Wang, Ji Chen, Gui-Qiang Wang

Pharmacology and Toxicology Faculty Publications

AIM: To determine which baseline factors of chronic hepatitis B patients are predictive of virological response to Peginterferon α-2b therapy. METHODS: A total of 21 HBeAg-positive chronic hepatitis B (CHB) patients treated with Peginterferon α-2b were recruited. They were treated with Peginterferon α-2b (0.5-1.0 µg/kg per week) for 24 wk and followed up for 24 wk. Clinical and laboratory data of the patients were determined at pretreatment and at week 12, at 24 during treatment, and at week 48 during follow up. RESULTS: Ten patients achieved a virological response at the end of treatment. Their baseline serum alanine aminotransferase (ALT), …

Transcriptional Profiling Differences For Articular Cartilage And Repair Tissue In Equine Joint Surface Lesions, Michael J. Mienaltowski, Liping Huang, David D. Frisbie, C. Wayne Mcilwraith, Arnold J. Stromberg, Arne C. Bathke, James N. Macleod

Veterinary Science Faculty Publications

BACKGROUND: Full-thickness articular cartilage lesions that reach to the subchondral bone yet are restricted to the chondral compartment usually fill with a fibrocartilage-like repair tissue which is structurally and biomechanically compromised relative to normal articular cartilage. The objective of this study was to evaluate transcriptional differences between chondrocytes of normal articular cartilage and repair tissue cells four months post-microfracture.

METHODS: Bilateral one-cm2 full-thickness defects were made in the articular surface of both distal femurs of four adult horses followed by subchondral microfracture. Four months postoperatively, repair tissue from the lesion site and grossly normal articular cartilage from within the same …

Medical School Watercooler Newsletter - September 13, 2009, Lindsey Lyle

Watercooler Newsletter

This is the September 13, 2009 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler

Contents Include

• Welcome Reception for New Chair of Surgery
• Pediatrics Presents Research Award
• 2009 Michael Moore Award
• Protect Yourself and Family From Seasonal Flu
• USA Researcher - Dr. Donna Cioffi Featured

Exploring The Effect Of Sexual Education On Sexual Health Risk Behaviors: Analysis Of The 2003 And 2007 Youth Risk Behavior Surveys In Florida And Alabama, Shenena Armstrong, Alicestine Ashford, Ivette A. López, C. Perry Brown

Florida Public Health Review

The purpose of this study was to explore the relationship between sexual health education content and sexual health risk behaviors, and the mediating effect of demographic variables. A cross-sectional research design employing secondary data analysis explored these associations in a sample of African American and non-Hispanic White male and female adolescents that took part in the Youth Risk Behavior Survey (YRBS) for the years 2003 and 2007 in the aforementioned southern states. Significant associations were observed between race and reported condom use and alcohol and/or drug use during last intercourse. For both Alabama and Florida, sexual health education was associated …

Progress Toward The Synthesis Of A Truncated Ergoline, Ryan D. Enck, Matthew Hart

Student Summer Scholars Manuscripts

Many people are diagnosed with thyroid related disorders, and many more are unaware of their existing thyroid problems. T1AM, a naturally occurring metabolite of the thyroid hormone (TH), has been shown to activate the Trace Amine Associated Receptor 1 (TAAR1) and exhibits effects that oppose those of the TH. It is, therefore, likely that there is regulatory relationship between T1AM and the TH. In order to better understand this relationship, a compound must be developed that will effectively block TAAR1. Previously our lab has examined the two different mirror images of apomorphine. One of the mirror images inhibited and the …

Estimating Effects By Combining Instrumental Variables With Case-Control Designs: The Role Of Principal Stratification, Russell T. Shinohara, Constantine E. Frangakis, Elizabeth Platz, Konstantinos Tsilidis

Johns Hopkins University, Dept. of Biostatistics Working Papers

The instrumental variable framework is commonly used in the estimation of causal effects from cohort samples. In the case of more efficient designs such as the case-control study, however, the combination of the instrumental variable and complex sampling designs requires new methodological consideration. As the prevalence of Mendelian randomization studies is increasing and the cost of genotyping and expression data can be high, the analysis of data gathered from more cost-effective sampling designs is of prime interest. We show that the standard instrumental variable analysis is not applicable to the case-control design and can lead to erroneous estimation and inference. …

Giant Adrenal Endothelial Cyst Associated With Acute And Chronic Morbidity In A Young Female: A Case Report., Muhammad Rizwan Khan, Saad Ajmal, Taimur Saleem

Department of Surgery Docs

Adrenal cysts are rare clinical entities that can present as acute abdomen through rupture and internal hemorrhage as well as chronic symptoms such as gastrointestinal disturbances. A 20-year-old girl presented to our hospital with a 4-years history of abdominal pain and diarrhea. Ultrasound of the abdomen revealed a cystic area measuring 10 x 10 cm between the spleen and left kidney. Computed tomography scan showed a large cystic, homogeneous mass measuring 12.8 x 9.5 x 9.4 cm in the left hypochondrium with most likely origin from the left adrenal gland. Limited work up for hormone hypersecretion was negative. The Patient …

Designing A Simulation For Student Evaluation Using Scriven's Key Evaluation Checklist, Shelly Jensen Reed

Faculty Publications

Human patient simulation use has increased dramatically in nursing education over the past 10 years, with many benefits. One advantage is that it allows students to learn by practicing skills in a risk-free environment, with immediate faculty feedback. Another benefit is that it prepares and ensures the competence of student nurses, leading to improved patient safety outcomes. Student opinions gathered in a survey of nursing schools and simulator centers favored use of competency evaluation using simulation in at least some circumstances. As little research concerning use of simulation to evaluate student competency can be found, an established guide such as …

Impairments In Attention In Occasionally Snoring Children: An Event-Related Potential Study., Maria E. Barnes, Elizabeth A. Huss, Krista N. Garrod, Eric Van Ray, Ehab Dayyat, David Gozal, Dennis L. Molfese

Faculty and Staff Scholarship

Objective: To determine whether minimal snoring is benign in children. Procedure: 22 rarely snoring children (mean age = 6.9 years, 11 females) and age- and sex-matched controls participated in an auditory oddball task wearing 128-electrode nets. Parents completed the Conners Parent Rating Scales–Revised Long (CPRS–R:L). Results: Snorers scored significantly higher on four CPRS-R:L subscales. Stepwise regression indicated that two ERP variables from a region of the ERP that peaked at 844 msec post-stimulus onset predicted CPRS-R:L Attention Deficit Hyperactivity Disorder (ADHD) Index scores. Conclusions: Occasional snorers, according to parental report, do exhibit ADHD-like behaviors. Basic sensory processing is longer than …

Family Education For Psychosis, Amresh Srivastava

Data and Test Instruments

No abstract provided.

Ada News - 09/07/2009, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Consider Intangibles When Weighing Olympic Host City Benefits, Rick Burton, Norm O'Relly

Sport Management - All Scholarship

No abstract provided.

Medical School Watercooler Newsletter- September 6, 2009, Lindsey Lyle

Watercooler Newsletter

This is the September 6, 2009 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler

Contents Include

• USA Pediatrician Featured in September Mobile Bay Monthly
• Dr. Errol Crook Talks About Healthcare Reform
• South Alabama Gears Up For The Flu Season
• Med Students Await Healthcare Speech
• Study: Smaller Dose Equally Effective Prep
• Med Students - In their Own Words
• Spotted At Jags Football Game

Revitalisation, Rigour And Relevance: The Citizen-Client And Planning In The Health Services., Vivienne Byers

Conference Papers

Whereas, in many OECD countries strategic planning in health care has been in evidence since the 1970s, in Ireland the emergence of strategic management processes in health care planning didn’t occur until the 1990s.

This paper reports on part of a comparative study of health services planning in Ireland and in Canada. How can the strategic management of the Irish health services in the form of service planning be implemented? The focus of this paper is the identification of two key stumbling blocks to success in this endeavour. These include the limitations of the control mechanism, the legislation, underpinning service …

Strategic Change In The Irish Health Services: Comparative Case Studies In Planning, Vivienne Byers

Conference Papers

This paper reports on a study of the implementation of service planning in the Irish health services in the context of significant organisational change. One of the central mechanisms of the Strategic Management Initiative (SMI) is the devolution of accountability and responsibility from the centre to executive agencies. Service planning in the Irish health care sector is seen as part of this strategic planning ethos.

This study in examining the function and implementation of the service plan in the Irish health care system drew comparisons with the Canadian experience. A multiple case study design was utilised. Key research questions were …

Broad Range Amino Acid Specificity Of Rna-Dependent Lipid Remodelling By Multiple Peptide Resistance Factors, Hervé Roy, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Aminoacylphosphatidylglycerol synthases (aaPGSs) are multiple peptide resistance factors that transfer amino acids from aminoacyl-tRNAs to phosphatidylglycerol (PG) in the cytoplasmic membrane. Aminoacylation of PG is used by bacteria to decrease the net negative charge of the cell envelope, diminishing affinity for charged molecules and allowing for adaptation to environmental changes. Lys-PGS, which transfers lysine to PG, is essential for the virulence of certain pathogens, providing resistance to both host cationic antimicrobial peptides and therapeutic antibiotics. Ala-PGS was also recently described, but little is known about the possible activities of other members of the highly diverse aaPGS family of proteins. Systematic …

Geographic Variation And Environmental Conditions As Cofactors In Chlamydia Psittaci Association With Ocular Adnexal Lymphomas: A Comparison Between Italian And African Samples, Alessandro Carugi, Anna Onnis, Giuseppina Antonicelli, Benedetta Rossi, Susanna Mannucci, Anna Luzzi, Stefano Lazzi, Cristiana Cristiana Bellan, Gian Marco Tosi, Shahin Sayed, Giulia De Falco, Lorenzo Leoncini

Pathology, East Africa

A particular extra-nodal lymphoma type arises from B cells of the marginal zone (MZ) of mucosa-associated lymphoid tissue (MALT). The aetiology ofMZ lymphomas suggests that they are associated with chronic antigenic stimulation by microbial pathogens, among which Helicobacter pylori-associated gastricMALT lymphoma is the best studied. Recently, MALT lymphomas have been described in the context of chronic conjunctivitis, which can be associated with Chlamydia spp. infection. Studies from Italy showed the presence of Chlamydia psittaci in 87% of ocular adnexal lymphomas (OAL), and C. psittaci has been described in a large part of samples from Austria and Korea as well. However, …

Adapting To Dynamic Stimulus-Response Values: Differential Contributions Of Inferior Frontal, Dorsomedial, And Dorsolateral Regions Of Prefrontal Cortex To Decision Making., Derek G V Mitchell, Qian Luo, Shelley B Avny, Tomasz Kasprzycki, Karanvir Gupta, Gang Chen, Elizabeth C Finger, R James R Blair

Brain and Mind Institute Researchers' Publications

Dorsomedial prefrontal cortex (dmPFC), dorsolateral prefrontal cortex (dlPFC), and inferior frontal gyrus (IFG) have all been implicated in resolving decision conflict whether this conflict is generated by having to select between responses of similar value or by making selections following a reversal in reinforcement contingencies. However, work distinguishing their individual functional contributions remains preliminary. We used functional magnetic resonance imaging to delineate the functional role of these systems with regard to both forms of decision conflict. Within dmPFC and dlPFC, blood oxygen level-dependent responses increased in response to decision conflict regardless of whether the conflict occurred in the context of …

Shoulder Rehabilitation For The Injured Overhead-Throwing Athlete, Joshua M. Raskoff

Recreation, Parks, and Tourism Administration

Baseball incorporates the violent motion of throwing as a main act of physical exertion. The shoulder joint is vulnerable to injury during this movement. The overall purpose of this study was to produce a rehabilitation program for injured overhead-throwing athletes and have it evaluated by healthcare professionals. A paper and pen style questionnaire was sent through the mail to a network of professionals in California. Eighteen of the 20 questionnaires were returned. The quantitative feedback of the Likert scale questions indicated that the program was effective and usable while the qualitative feedback indicated the opposite. The additional comments allowed experts …

Integrative Health Studies Newsletter, Ciis

Integrative Health Studies Newsletter

This is the Fall 2009 issue of the Integrative Health Studies Newsletter at CIIS.

Measuring Illness Uncertainty In Men Undergoing Active Surveillance (As) For Prostate Cancer, Peter C. Albertsen

Articles - Patient Care

Uncertainty is an aversive experience and plays an important role in the lives of men undergoing active surveillance (AS) (earlier referred to as watchful waiting) for early-stage prostate cancer. Yet reliable and valid measures of uncertainty have not been fully tested in this population. This secondary analysis therefore tested the reliability of the Mishel Uncertainty in Illness Scale – Community Form (MUIS-C; Mishel, 1997b) for use with a population of men undergoing AS for prostate cancer.

New Tfii-I Family Target Genes Involved In Embryonic Development, Aleksandr V. Makeyev, Dashzeveg Bayarsaihan

SoDM Articles

Two members of the TFII-I family transcription factor genes, GTF2I and GTF2IRD1, are the prime candidates responsible for the craniofacial and cognitive abnormalities of Williams syndrome patients. We have previously generated mouse lines with targeted disruption of Gtf2ird1 and Gtf2i. Microarray analysis revealed significant changes in the expression profile of mutant embryos. Here we described three unknown genes that were dramatically down-regulated in mutants. The 2410018M08Rik/Scand3 gene encodes a protein of unknown function with CHCH and hATC domains. Scand3 is downregulated during mouse embryonic stem cell (ES) differentiation. 4933436H12Rik is a testis-specific gene, which encodes a protein with no known …

Effects Of Nicotine Patch Or Nasal Spray On Nicotine And Cotinine Concentrations In Pregnant Smokers, Cheryl A. Oncken, Winston A. Campbell, Grace Chan, Henry R. Kranzler

UCHC Articles - Research

Objective To examine the short-term effects of the nicotine patch or nasal spray on measures of nicotine exposure, withdrawal symptoms, and on maternal and fetal heart rates in pregnant smokers. Methods We measured nicotine/cotinine concentrations and maternal and fetal heart rates during an 8-hour monitoring session while smoking and again after 4 days of nicotine patch (15 mg/16 hours), nasal spray (recommended regimen of 24 doses per day), or placebo treatment. Nicotine withdrawal symptoms were assessed daily. Results Twenty-one subjects, who smoked an average of 17 cigarettes per day, completed both monitoring sessions. Nicotine concentrations decreased from baseline smoking concentrations …

Medical Education Digest, Vol. 11 No. 5 (September/October 2009), Nova Southeastern University

Medical Education Digest

No abstract provided.

Women Bound To Be Active: One Year Follow-Up To An Innovative Pilot Intervention To Increase Physical Activity And Self-Worth In Women, Jennifer L. Huberty, Jamie Vener, Laura Schulte, Sara M. Roberts, Beth Stevens, Lynda Ransdell

Kinesiology Faculty Publications and Presentations

The purpose of this investigation was to assess the effectiveness of a lifestyle intervention (a women’s book club; Women Bound to be Active) in promoting long-term physical activity (PA). Thirty-five women (26-70 years; mean age 50.6 years) completed the 8-month intervention and participated in the one-year follow-up. At follow-up, PA returned to baseline levels; however, self-worth and body mass index significantly improved. Women were more knowledgeable about PA at follow-up; however, they failed to maintain PA after the intervention. Components of the intervention were effective in improving self-worth and lowering BMI at one-year follow-up. To enhance long-term PA adherence continued …

ความสามารถของกลุ่มตัวอย่างในการเคลื่อน ขากรรไกรตามคําบอกของทันตแพทย์, พนมพร วานิชชานนท์, ขนิษฐา สายสุด, จินตนา อยู่เย็น, ณัฐพงษ์ ลาบึง

Chulalongkorn University Dental Journal

วัตถุประสงค์ เพื่อศึกษาว่ากลุ่มตัวอย่างสามารถเคลื่อนขากรรไกรไปยังแต่ละตําแหน่งตามคําบอกของทันตแพทย์ได้ถูกต้องมากน้อยเพียงใดและหาวิธีการที่เหมาะสมที่สุดเพื่อให้กลุ่มตัวอย่างเคลื่อนขากรรไกรได้ถูกต้อง วัสดุและวิธีการ สัมภาษณ์อาจารย์ทันตแพทย์ 18 ท่านถึงวิธีการที่ใช้บอกผู้ป่วยให้เคลื่อนขากรรไกรไปยังตําแหน่ง ต่อไปนี้ 1) สบฟันให้ได้พื้นที่สัมผัสมากที่สุด 2) เยื้องขากรรไกรขวา-ซ้าย 3) ยื่นขากรรไกร 4) อ้าปากกว้างมากที่สุด คัดเลือกวิธีที่ใช้มากที่สุด 4 วิธี นําไปทดสอบกับกลุ่มตัวอย่างจํานวน 102 คน อาจารย์ทันตแพทย์หนึ่งท่านเป็น ผู้ตรวจการเคลื่อนขากรรไกรทุกตําแหน่ง สําหรับการอ้าปากกว้างที่สุด วิธีการที่ทําให้ได้ระยะห่างจากปลายฟันหน้า บน-ล่างมากที่สุดจะถือว่าเป็นวิธีที่ถูกต้อง ผลการศึกษา กลุ่มตัวอย่างเคลื่อนขากรรไกรได้ถูกต้องมากน้อยเพียงใดขึ้นกับวิธีการที่ใช้ (p < 0.05) วิธีการที่กลุ่ม ตัวอย่างทําได้ถูกต้องมากที่สุดในแต่ละตําแหน่งได้แก่ 1) ตําแหน่งสบฟันให้ได้พื้นที่มากที่สุด โดยทันตแพทย์ใช้นิ้ว แตะแก้มบริเวณพื้นหลังทั้งสองข้างของกลุ่มตัวอย่างและบอกว่า “กัดลงมาตรงนี้” (ร้อยละ 91.2) 2) ตําแหน่งเยื้อง ขากรรไกรขวา-ซ้าย โดยทันตแพทย์บอกว่า “เยื้องขากรรไกรไปด้านขวา (หรือซ้าย” พร้อมกับให้ตัวอย่างดูกระจก ร่วมด้วย (ร้อยละ 84.3 และ 79.4 ตามลําดับ) 3) ตําแหน่งยื่นขากรรไกร โดยทันตแพทย์ทําให้ดูเป็นตัวอย่างก่อน (ร้อยละ 97.1) ส่วนการอ้าปากกว้างมากที่สุด ให้ทันตแพทย์บอกว่า “อ้าปากกว้างสุด ๆ” แล้วพูดว่า “กว้างอีกนิดได้ไหม” (ร้อยละ 65.09) สรุป ตัวอย่างแต่ละคนมีความสามารถในการเคลื่อนขากรรไกรตามคําบอกของทันตแพทย์แตกต่างกันทั้งในแต่ละ ตําแหน่งและวิธีการ โดยที่พบปัญหาการเคลื่อนขากรรไกรไปด้านข้างมากกว่าตําแหน่งอื่น (ว ทันต จุฬาฯ 2552;32:213-24)

การรั่วซึมของเทคนิคการอุดย้อนปลายราก 2 แบบ, ทิพวัลย์ อินทรฤทธิ์, ปิยาณี พาณิชย์วิสัย

Chulalongkorn University Dental Journal

วัตถุประสงค์ เพื่อศึกษาเปรียบเทียบการรั่วซึมของเทคนิคการอุดย้อนปลายรากชนิดใช้วัสดุเอ็มทีเอกับชนิดใช้วัสดุเรซินคอมโพสิตชนิดไหลแผ่เป็นวัสดุอุดย้อนปลายรากฟัน ทั้งกรณีที่มีและไม่มีการปนเปื้อนด้วยเลือด วัสดุและวิธีการ ฟันหน้าบนของมนุษย์ที่มีคลองรากเดียวขนาดใกล้เคียงกันจํานวน 68 ที่ถูกถอนออกด้วย เหตุผลทางการแพทย์ นํามาตัดส่วนตัวฟันออกให้เหลือความยาวราก 15 มิลลิเมตร ขยายคลองรากฟันแล้ว อุดคลองรากฟันด้วยกัตตาเปอร์ชาและเอเอ็ชพลัสรูทคาแนลซีลเลอร์ ทําการตัดปลายราก 3 มิลลิเมตร แบ่งรากฟัน ออกเป็น 4 กลุ่มการทดลอง (กลุ่มละ 15 ราก) และ 2 กลุ่มควบคุม (กลุ่มละ 4 ราก) สองกลุ่มการทดลองแรก เตรียมปลายรากฟันด้วยหัวอัลตราโซนิกส์ลึก 3 มิลลิเมตร แล้วอุดย้อนปลายรากด้วยวัสดุเอ็มทีเอ ทั้งแบบที่มีและ ไม่มีการปนเปื้อนด้วยเลือด อีกสองกลุ่มการทดลองเตรียมปลายรากฟันด้วยหัวกรอรูปกลมกรอปลายรากฟันให้มีรูปร่างเว้าเล็กน้อย อุดย้อนปลายรากฟันด้วยวัสดุเรซินคอมโพสิตชนิดไหลแผ่ ทั้งแบบที่มีและไม่มีการปนเปื้อน ด้วยเลือด ประเมินการรั่วซึมโดยใช้สีเมทธีลีนบลูในระบบสุญญากาศ วิเคราะห์ผลโดยใช้สถิติวิเคราะห์ความ แปรปรวนสองทางที่ระดับนัยสําคัญ 0.05 ผลการศึกษา กลุ่มการทดลองที่ใช้เทคนิคเตรียมปลายรากฟันให้มีรูปร่างเว้าเล็กน้อย แล้วอุดย้อนปลายรากฟัน ด้วยวัสดุเรซินคอมโพสิตชนิดไหลแผ่ แบบที่ไม่มีการปนเปื้อนด้วยเลือด มีการรั่วซึมของสีน้อยกว่ากลุ่มทดลองอื่น อย่างมีนัยสําคัญทางสถิติที่ระดับ 0.05 สรุป การรั่วซึมของการอุดย้อนปลายรากฟันด้วยวัสดุเอ็มทีเอและวัสดุเรซินคอมโพสิตชนิดไหลแผ่ ขึ้นกับเทคนิคการอุดย้อนปลายรากและปัจจัยของการปนเปื้อนด้วยเลือด โดยเทคนิคเตรียมปลายรากฟันให้มีรูปร่างเว้าเล็กน้อย แล้วอุดย้อนปลายรากฟันด้วยวัสดุเรซินคอมโพสิตชนิดไหลแผ่ แบบที่ไม่มีการปนเปื้อนด้วยเลือด มีการรั่วซึมน้อยที่สุด (ว ทันต จุฬาฯ 2552;32:167-78)