Medicine and Health Sciences Commons^™

Child Maltreatment History Among Newlywed Couples : A Longitudinal Study Of Marital Outcomes And Mediating Pathways, David Dilillo, James Peugh, Kate Walsh, Jillian Panuzio, Emily Trask, Sarah Evans

Department of Psychology: Faculty Publications

Participants included 202 newlywed couples who reported retrospectively about child maltreatment experiences (sexual abuse, physical abuse, psychological abuse, and neglect) and whose marital functioning was assessed 3 times over a 2-year period. Decreased marital satisfaction at T1 was predicted by childhood physical abuse, psychological abuse, and neglect for husbands; only neglect predicted lower satisfaction for wives. Increased maltreatment of various types was also related to T1 difficulties with marital trust and partner aggression. Dyadic growth curve analyses showed that the marital difficulties reported at T1 tended to remain over the course of the study. Further, in several instances, maltreatment exerted …

Severity Of Child Sexual Abuse And Revictimization: The Mediating Role Of Coping And Trauma Symptoms, Michelle A. Fortier, David Dilillo, Terri L. Messman-Moore, James Peugh, Kathleen A. Denardi, Kathryn J. Gaffey

Department of Psychology: Faculty Publications

Child sexual abuse (CSA) has consistently been associated with the use of avoidant coping; these coping methods have been associated with increased trauma symptoms, which have, in turn, been linked to increased risk for adult sexual revictimization. Given these previous findings, the purpose of the current study was to test a model that conceptualized the relationships among these variables. Specifically, CSA severity was conceptualized as leading to the use of avoidant coping, which was proposed to lead to maintenance of trauma symptoms, which would, in turn, impact severity of revictimization indirectly. This comprehensive model was tested in a cross-sectional study …

Impulsivity And Cigarette Craving: Differences Across Subtypes, Neal Doran, Jessica Werth Cook, Dennis E. Mcchargue, Bonnie Spring

Department of Psychology: Faculty Publications

Rationale: Cigarette smoking has been linked to a number of personality characteristics, including impulsivity. Smokers tend to endorse high levels of impulsivity, and more impulsive smokers have greater difficulty quitting, but little is known about potential explanatory mechanisms. Although indirect evidence suggests craving as a candidate mechanism, direct evidence has been mixed.
Materials and methods: This study assessed whether specific aspects of impulsivity (sensation seeking, lack of premeditation, lack of perseverance, and urgency) were associated with cue-induced craving. Regular smokers (n= 60; 50% female) were exposed to a smoking cue and a neutral cue in a repeated measure …

Repeated Antipsychotic Treatment Progressively Potentiates Inhibition On Phencyclidine-Induced Hyperlocomotion, But Attenuates Inhibition On Amphetamine-Induced Hyperlocomotion: Relevance To Animal Models Of Antipsychotic Drugs, Tao Sun, Gang Hu, Ming Li

Department of Psychology: Faculty Publications

Clinical obervations indicate that antipsychotic action starts early and increases in magnitude with repeated treatment. Animal models that faithfully capture this time course of action are few. Inhibition of hyperlocomotion induced by amphetamine or phencyclidine has been widely used as a screening tool for the antipsychotic activity of a drug. We thus investigated whether repeated antipsychotic treatment could produce an early-onset and progressively increased antagonistic effect on amphetamine or phencyclidine-induced hyperlocomotion as a way of assessing the validity of such models in capturing time course of antipsychotic action. One each of the five consecutive test days, different groups of rats …

Sedation And Disruption Of Maternal Motivation Underlie The Disruptive Effects Of Antipsychotic Treatment On Rat Maternal Behavior, Changjiu Zhao, Ming Li

Department of Psychology: Faculty Publications

The behavioral mechanisms underlying antipsychotic-induced maternal behavior deficits were examined in the present study. Different groups of postpartum rats were treated with haloperidol (0.1 mg/kg), clozapine (10.0 mg/kg), chlordiazepoxide (5.0 mg/kg, an anxiolytic) or vehicle (0.9% saline) on Days 4 and 6 postpartum and their maternal behaviors were tested under either pup-separation (e.g. pups were removed from their mothers for 4 h before testing) or no-pup-separation condition. Maternal behavior and drug-induced sedation were further tested for 3 days from Day 8 to 12 postpartum. Results show that pup-separation, which putatively increases maternal motivation, did significantly shorten clozapine-elongated pup approach latency, …

Persons As Contexts: Evaluating Between-Person And Within-Person Effects In Longitudinal Analysis, Lesa Hoffman, Robert S. Stawski

Department of Psychology: Faculty Publications

Relationships among multiple variables over time are of interest in many developmental areas and are frequently examined using time-varying predictors in multilevel models. Yet an incomplete specification of time-varying predictors will usually result in biased model effects. Specifically, the impact of constant, between-person sources of variation must be differentiated from the impact of time-specific, within-person sources of variation -that is, persons should be modeled as contexts. The current didactic article expands upon previous work to address why and how to model persons as contexts in longitudinal analysis. An electronic appendix of syntax for estimating these models is also provided.

Daily Negative Mood Affects Fasting Glucose In Type 2 Diabetes, Marilyn M. Skaff, Joseph T. Mullan, David M. Almeida, Lesa Hoffman, Umesh Masharani, David C. Mohr, Lawrence Fisher

Department of Psychology: Faculty Publications

Objective—To examine the relationship between mood and blood glucose in a 21 day daily diary study.

Design—During a home visit, information was gathered from two hundred six persons with type 2 diabetes regarding demographics, disease characteristics and treatment, and depressive symptoms. They had blood drawn at a laboratory, yielding HbA1C. The participants were then telephoned each evening for 21 days and were asked about their positive and negative mood during the past 24 hours. They also tested their blood glucose upon rising in the morning.

Main Outcome Measures—The main outcomes measures were positive and negative affect and fasting glucose.

Results—Multilevel …

Rational Decisions: The Adaptive Nature Of Context-Dependent Choice, Alexandra G. Rosati, Jeffrey R. Stevens

Department of Psychology: Faculty Publications

Although classical economic theory hinges on the assumption that rational actors should seek to maximize gains, psychologists and behavioral economists have recently collected a wealth of evidence challenging this premise. In violation of the principles of rational choice, context appears to dramatically influence human decision making. Like humans, numerous nonhuman animals, ranging from honeybees to primates, are sensitive to context, suggesting deep evolutionary roots for seemingly irrational decision-making. Many psychologists have suggested that such choices may stem from cognitive biases that result in errors. We contend, however, that labeling context-dependent choices as errors obscures the real issue. Natural selection does …

The Dynamics Of Development: Challenges For Bayesian Rationality, Nils Straubinger, Edward T. Cokely, Jeffrey R. Stevens

Department of Psychology: Faculty Publications

Commentary on Oaksford & Chater, Precis of Bayesian Rationality

Oaksford & Chater draw a rather static picture of human reasoning by focusing on typical patterns of responses from adults. We propose a more dynamic perspective, which considers that reasoning systematically varies within individuals over the lifespan (Howe & Rabinowitz 1996; Markovits & Barrouillet 2002) and between individuals with different levels of knowledge and expertise (Ericsson et al. 2006).

The original articles, the full set of commentaries, and the authors' response are attached (below) as an "Additional file."

Social Interaction Effects On Reward And Cognitive Abilities In Monkeys, Jeffrey R. Stevens, Marc D. Hauser

Department of Psychology: Faculty Publications

When given a choice between receiving $100 in 30 days and $110 in 31 days, most people wait for the larger, more delayed reward. However, when the choice is between $100 today and $110 tomorrow, many people shift their preferences to the smaller, immediate reward despite the same difference of $10 and one day. Reward properties—such as time to receipt—play a crucial role in our processing of rewards. However, reward processing does not only occur for individual decisions but also for social interactions; we must decide to either cooperate or compete with others for rewards. Humans stand out in the …

Content Validity Of Nutrition Diagnostic Term Involuntary Weight Loss, Paula K. Ritter-Gooder, Nancy M. Lewis

Department of Nutrition and Health Sciences: Faculty Publications

Objective The purpose of this study was to validate content of the Nutrition Diagnostic Term NC- 3.2 Involuntary Weight Loss using expert raters.

Design/Subjects This descriptive survey invited all Board Certified Specialists in Gerontological Nutrition (CSG) to participate by mail. An instrument was developed that included the definition, etiologies, and signs and symptoms (s/s) of the diagnosis with items added from literature review. CSG rated how common or characteristic each item is to the diagnosis using a 5 point Likert scale. A weighted response for each item was used to calculate a Diagnostic Content Validity (DCV) score. DCV scores of …

In Vivo Selection Of Plasmodium Falciparum Parasites Carrying The Chloroquine-Susceptible Pfcrt K76 Allele After Treatment With Artemether-Lumefantrine In Africa, C. Sisowath, I. Petersen, M.I. Veiga, A. Martensson, Zul Premji, A. Bjorkman, D.A. Fidock, J.P. Gil

Pathology, East Africa

Background: Artemether-lumefantrine (AL) is a major and highly effective artemisinin-based combination therapy that is becoming increasingly important as a new first-line therapy against Plasmodium falciparum malaria. However, recrudescences occurring after AL treatment have been reported. Identification of drug-specific parasite determinants that contribute to treatment failures will provide important tools for the detection and surveillance of AL resistance.

Methods: The findings from a 42-day follow-up efficacy trial in Tanzania that compared AL with sulfadoxinepyrimethamine (SP) were analyzed to identify candidate markers for lumefantrine tolerance/resistance in the chloroquine resistance transporter gene (pfcrt) and multidrug resistance gene 1 (pfmdr1). The findings were corroborated …

The Guinea Pig Ileum Lacks The Direct, High-Potency, M2-Muscarinic, Contractile Mechanism Characteristic Of The Mouse Ileum, Michael T. Griffin, Minoru Matsui, Rennolds S. Ostrom, Frederick J. Ehlert

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

We explored whether the M2 muscarinic receptor in the guinea pig ileum elicits a highly potent, direct-contractile response, like that from the M3 muscarinic receptor knockout mouse. First, we characterized the irreversible receptor-blocking activity of 4-DAMP mustard in ileum from muscarinic receptor knockout mice to verify its M3 selectivity. Then, we used 4-DAMP mustard to inactivate M3 responses in the guinea pig ileum to attempt to reveal direct, M2 receptor-mediated contractions. The muscarinic agonist, oxotremorine-M, elicited potent contractions in ileum from wild-type, M2 receptor knockout, and M3 receptor knockout mice characterized by negative log EC50 (pEC 50 ) values ± …

Understanding Middle School Students' Perspectives Regarding Physical Activity And Fitness, Susan Yesalonia

Walden Dissertations and Doctoral Studies

Research confirms inactivity increases in adolescence and that unfit youth are at risk of acquiring cardiovascular diseases, diabetes, obesity, or other significant physical disorders later in life. Thus, the purpose of this phenomenological study was to describe the experience of chronically inactive children who were exposed to an exercise intervention program. The specific focus of the research was to better understand the essential educational needs of the participants and the effective elements of the program, Moving for Fun (MFF), a 7-week after-school fitness intervention program designed to modify chronic inactivity. Open-ended interviews and 3 observations were conducted with 8 middle …

A Comparison Of Lifestyle Intervention Sessions And Clinical Screening As Motivators In The South Dakota Wisewoman Program, Jacy Clarke

Walden Dissertations and Doctoral Studies

WISEWOMAN (WW) is a comprehensive program for medically underserved women in South Dakota (SD), aged 30 to 64, which aims to reduce morbidity and mortality from chronic diseases. Screening services include blood total cholesterol, blood pressure and blood glucose, and body mass index (BMI). Lifestyle intervention (LSI) sessions are also offered to address physical activity and nutrition. The purpose of this retrospective longitudinal study was to quantitatively examine whether the combination of LSI's and clinical screenings or clinical screenings alone lead to improvements in blood pressure, blood glucose, total cholesterol, and/or BMI at rescreening 10 to14 months from initial screening. …

Personal And Professional Spirituality: Muslim Social Workers' Perspectives, Cheryl W. El-Amin

Walden Dissertations and Doctoral Studies

Research in the area of religion and spirituality in social work practice is lacking minority practitioner representation. This phenomenological study explored the questions of how American Muslim social workers define and experience the religious/spiritual, and perceive the propriety of integrating either, in practice. Ibn Khaldun and Durkheim, early social theorists, suggested that group feeling and affiliation impact personal and professional perception and decision making. American societal views of Muslims are often negative and uninformed. A group of 15 Muslim practitioners with bachelor's or more advanced degrees in social work were recruited through a survey administered via an Internet survey site. …

Faces In The Mirror: Exploring Conflict Styles Of Adults In School Communities Using The Face -Negotiation Theory, Christine D. Gross

Walden Dissertations and Doctoral Studies

This correlation study focused on the lack of understanding of the relationship between social self-image "face" and conflict styles among adult employees on school campuses. An individual's social self-image may involve concerns for the social representation of oneself, another individual, or a relationship. Limited research pertaining to the degree face concerns affect conflict styles within school communities is a problem for school administrators because conflict styles can influence conflict outcomes and impact workplace quality on school campuses. This study relied on Ting-Toomey's face-negotiation theory, which proposes that individuals prefer conflict styles based upon face concerns. Research questions explored correlations between …

Sample Size Calculation For Finding Unseen Species, Hongmei Zhang, Hal Stern

Faculty Publications

Estimation of the number of species extant in a geographic region has been discussed in the statistical literature for more than sixty years. The focus of this work is on the use of pilot data to design future studies in this context. A Dirichlet-multinomial probability model for species frequency data is used to obtain a posterior distribution on the number of species and to learn about the distribution of species frequencies. A geometric distribution is proposed as the prior distribution for the number of species. Simulations demonstrate that this prior distribution can handle a wide range of species frequency distributions …

Micrornas: Key Modulators Of Posttranscriptional Gene Expression., Steven P. O'Hara, Justin L. Mott, Patrick L. Splinter, Gregory J. Gores, Nicholas F. Larusso

Journal Articles: Biochemistry & Molecular Biology

No abstract provided.

Elevated Expression Of L-Selectin Ligand In Lymph Node-Derived Human Prostate Cancer Cells Correlates With Increased Tumorigenicity., Prakash Radhakrishnan, Ming-Fong Lin, Pi-Wan Cheng

Journal Articles: Biochemistry & Molecular Biology

Human prostate cancer LNCaP cells including C-33 and C-81 cells were originally derived from the lymph nodes of a patient with metastatic prostate cancer. These two cells were employed for characterization of L-selectin ligand and in vitro tumorigenicity, because they mimic the clinical conditions of early and late-stage human prostate cancer. C-81 cells exhibit higher in vitro migratory and invasive properties as compared with C-33 cells. We find that the L-selectin ligand and mucin glycan-associated MECA-79 epitope were elevated in C-81 cells. An increase of these glycotopes positively correlates with elevated tumorigenicity and expression of key glycosyl- and sulfotransferase genes. …

The Impact Of Centre Based Respite On Occupational Performance For People With Dementia, Kristy Ness

Theses : Honours

Dementia affects occupational performance by restricting one's ability to carry out valued roles and activities. Centre based respite has been described as one intervention to maintain or improve occupational performance and prevent or delay institutionalisation for people with dementia. The purpose of this study was to explore the impact of centre based respite on occupational performance components as outlined by the Occupational Performance Model (Australia) for people with dementia. Five spousal caregivers, recruited through Alzheimer's Australia WA, participated in semi-structured interviews. Data was analysed using framework analysis techniques. Findings revealed centre based respite attendance can positively influence marital relationships, mood, …

An Analysis Of Use Of Equipment And Respite Services By Families With A Daughter With Rett Syndrome, Anna Urbanowicz

Theses : Honours

Purpose: This literature review examines the body of knowledge concerning the use of respite services and assistive products and technology, child and family characteristics, and parental well-being among families with a daughter with Rett syndrome or with a child with another developmental disability. Method: Literature published in the time period 1983-2009 was searched. Studies were included in this review if they reported use of respite services or assistive products and technology among families with a daughter with Rett syndrome or with a child with another developmental disability. Child and family characteristics and parental well-being were also considered. Results and conclusions: …

Powered Mobility As An Intervention For Children With Cerebral Palsy: A Systematic Review ; The Smart Wheelchair: Is It An Appropriate Mobility Training Tool For Children With Cerebral Palsy?, Sarah Mcgarry

Theses : Honours

Purpose. To systematically review the effectiveness of powered mobility training interventions in improving driving skills and psychosocial outcomes in children with cerebral palsy. Method. Electronic searches of CINAHL, Medline and Meditext were conducted. Using two assessment tools, two independent reviewers assessed the quality of selected studies and level of evidence. Studies were included if a powered mobility training intervention was described, at least one participant had cerebral palsy and if the majority of participants were aged between 18 months and 18 years old. A narrative analysis was conducted. Results. Seven articles were eligible for inclusion. Intervention protocols included computer simulator …

Wikipedia, Me, And Ohp, Irvin Sam Schonfeld

Publications and Research

No abstract provided.

Étude Exploratoire Des Parcours D’Emploi En Lien Avec L’Apparition Des Premières Lésions Chez Les Jeunes De 16 À 24 Ans, Jean-François Godin, Benoît Laplante, Élise Ledoux, Mircea Vultur, Zacharie Tsala Dimbuene

Rapports de recherche scientifique

Depuis une vingtaine d’années, plusieurs études ont mis en évidence le fait que les jeunes de moins de 25 ans se blessent suffisamment fréquemment au travail pour que cette situation devienne une préoccupation de santé publique tant au Canada, aux États-Unis qu’en Europe. Au Québec, ce constat préoccupe de plus en plus les partenaires du réseau de la SST.

À ce jour, la problématique des jeunes et de la santé et sécurité du travail a surtout été documentée à partir d’enquêtes transversales. Ces analyses ont permis d’identifier, entre autres, les secteurs d’activité et les types d’emploi où se produisent le …

Visitor Perceptions Of Benefits Of Local Park, Deborah L. Kerstetter, Andrew J. Mowen, Nate E. Trauntvein, Toni Liechty, Nuno Rubiero

Kinesiology and Health Science Faculty Publications

Recent research regarding the perceived benets of local parks has been limited, posing a problem for recreation and park directors who must promote the value of and gain support for aging park facilities. To collect evidence concerning the value of local parks and the impact of park upgrades, we conducted a study with one local park to (a) document behavioral changes that have occurred as a result of renovation, and (b) determine the perceived benets of having a community park. Two-thirds of respondents reported visiting the park more frequently since renovations were completed. When asked why they visit the park …

The Interaction Of Hab18g/Cd147 With Integrin Alpha6beta1 And Its Implications For The Invasion Potential Of Human Hepatoma Cells., Jing-Yao Dai, Ke-Feng Dou, Cong-Hua Wang, Pu Zhao, Wayne Bond Lau, Ling Tao, Ya-Mei Wu, Juan Tang, Jian-Li Jiang, Zhi-Nan Chen

Department of Emergency Medicine Faculty Papers

BACKGROUND: HAb18G/CD147 plays pivotal roles in invasion by hepatoma cells, but the underlying mechanism remains unclear. Our previous study demonstrated that overexpression of HAb18G/CD147 promotes invasion by interacting with integrin alpha3beta1. However, it has never been investigated whether alpha3beta1 is solely responsible for this process or if other integrin family members also interact with HAb18G/CD147 in human hepatoma cells. METHODS: Human SMMC-7721 and FHCC98 cells were cultured and transfected with siRNA fragments against HAb18G/CD147. The expression levels of HAb18G/CD147 and integrin alpha6beta1 were determined by immunofluorescent double-staining and confocal imaging analysis. Co-immunoprecipitation and Western blot analyses were performed to examine …

Health Care In America: Historical Context, Current Issues, Future Reform, Emily Boevers

Honors Program Theses

In studying this topic, I used print resources from the last thirty years to investigate the history of the medical profession, including the ideals that shaped it and have bound it for more than 100 years. I studied the attempts at health care reform in the last 100 years, through numerous wars, economic crises, and political flux. I summarized health care systems from ten other developed nations to understand what is working - and what is not - in health care around the world. I surveyed issues plaguing the health care system in America today, and studied the trends that …

From School To Practice: The Meaning Of Nurses' Holistic Comfort, Michal Goodwin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Nurses entering the healthcare arena are likely to encounter a gap in preparation from school to practice. Despite well-intentioned transition programs, nurses struggle to keep up with the reality of demanding schedules, stressful work environments and non-nursing tasks, such as their own comfort. Holistic comfort, a well-known concept in patient care, offers an innovative approach to nursing education to sustain new nurses transitioning into practice. This phenomenological study explored how nurses who experienced holistic comfort in their schooling were able to use the same philosophical approach to transcend unavoidable difficulties early in their careers.

Newly practicing nurses from a program …

Biofeedback Assisted Relaxation Training Program To Decrease Test Anxiety In Nursing Students, Catherine Andrea Prato

UNLV Theses, Dissertations, Professional Papers, and Capstones

Nursing programs have been cited as being among the most stressful undergraduate programs. Students' knowledge and skills are consistently tested and monitored, and students may fail a course or be dropped from their nursing program if scores are not above a certain standard. Anxiety reactions are common to situations perceived as threatening; however, excessive anxiety may paralyze an individual and interfere with effective learning, functioning, and testing. Numerous studies have found increased anxiety causes physiological changes including increased respirations and heart rate, and decreased peripheral skin temperature. The purpose of this study was two fold. First test anxiety was measured …