Medicine and Health Sciences Commons^™

Arbovirus Infection Increases With Group Size, Charles R. Brown, Nicholas Komar, Sunita B. Quick, Rajni A. Sethi, Nicholas A. Panella, Mary Bromberger Brown, Martin Pfeffer

Zoonotics and Wildlife Disease: Publications

Buggy Creek (BCR) virus is an arthropod-borne alphavirus that is naturally transmitted to its vertebrate host the cliff swallow (Petrochelidon pyrrhonota) by an invertebrate vector, namely the cimicid swallow bug (Oeciacus vicarius). We examined how the prevalence of the virus varied with the group size of both its vector and host. The study was conducted in southwestern Nebraska where cliff swallows breed in colonies ranging from one to 3700 nests and the bug populations at a site vary directly with the cliff swallow colony size. The percentage of cliff swallow nests containing bugs infected with BCR …

Public Beliefs About The Preventability Of Unintentional Injury Deaths, Deborah C. Girasek

Uniformed Services University of the Health Sciences

This report is based upon the results of a national random digit dialed telephone survey in which 943 adults were queried. Subjects reported the proportion of deaths due to motor vehicle crashes, falls, fires/burns, drowning and poisoning that they felt were preventable. On average, respondents believed that 56% of ‘fatal accidents’ were preventable; as were 62% of motor vehicle crash deaths, 53% of fall deaths, 67% of drownings, 62% of fire/burn fatalities and 70% of accidental poisonings. Logistic regression models predicting preventability beliefs differed according to the type of injury event in question, but socio-economic status and perceived alcohol involvement …

Predictors Of Patient Satisfaction, Jeffrey L. Jackson, Judith Chamberlin, Kurt Kroenke

Uniformed Services University of the Health Sciences

Correlates of patient satisfaction at varying points in time were assessed using a survey with 2-week and 3-month follow-up in a general medicine walk-in clinic, in USA. Five hundred adults presenting with a physical symptom, seen by one of 38 participating clinicians were surveyed and the following measurements were taken into account: patient symptom characteristics, symptom-related expectations, functional status (Medical Outcomes Study Short-Form Health Survey [SF-6]), mental disorders (PRIME-MD), symptom resolution, unmet expectations, satisfaction (RAND 9-item survey), visit costs and health utilization. Physician perception of difficulty (Difficult Doctor-Patient Relationship Questionnaire), and Physician Belief Scale. Immediately after the visit, 260 (52%) …

Tsc13p Is Required For Fatty Acid Elongation And Localizes To A Novel Structure At The Nuclear-Vacuolar Interface In Saccharomyces Cerevisiae, Sepp D. Kohlwein, Sandra Eder, Chan-Seok Oh, Charles E. Martin, Ken Gable, Dagmar Bacikova, Teresa Dunn

Uniformed Services University of the Health Sciences

The TSC13/YDL015c gene was identified in a screen for suppressors of the calcium sensitivity of csg2Δ mutants that are defective in sphingolipid synthesis. The fatty acid moiety of sphingolipids in Saccharomyces cerevisiae is a very long chain fatty acid (VLCFA) that is synthesized by a microsomal enzyme system that lengthens the palmitate produced by cytosolic fatty acid synthase by two carbon units in each cycle of elongation. The TSC13 gene encodes a protein required for elongation, possibly the enoyl reductase that catalyzes the last step in each cycle of elongation. The tsc13 mutant accumulates high levels of long-chain bases …

Absence Of All Components Of The Flagellar Export And Synthesis Machinery Differentially Alters Virulence Of Salmonella Enterica Serovar Typhimurium In Models Of Typhoid Fever, Survival In Macrophages, Tissue Culture Invasiveness, And Calf Enterocolitis, Clare K. Schmitt, Jack S. Ikeda, Stephen C. Darnell, Patricia R. Watson, Jennifer Bispham, Timothy S. Wallis, Debra L. Weinstein, Eleanor S. Metcalf, Alison D. O'Brien

Uniformed Services University of the Health Sciences

In this study, we constructed an flhD (the master flagellar regulator gene) mutant of Salmonella enterica serovar Typhimurium and compared the virulence of the strain to that of the wild-type strain in a series of assays that included the mouse model of typhoid fever, the mouse macrophage survival assay, an intestinal epithelial cell adherence and invasion assay, and the calf model of enterocolitis. We found that the flhD mutant was more virulent than its parent in the mouse and displayed slightly faster net growth between 4 and 24 h of infection in mouse macrophages. Conversely, the flhD mutant exhibited diminished …

Introduction: Fear And Loathing Of Evolutionary Psychology In The Social Sciences, Daniel Leger, Alan Kamil, Jeffrey A. French

Department of Psychology: Faculty Publications

When one looks at the intellectual landscape of the modern university, at the scholarly and scientific interests of its faculty, the panorama is seamless. There are no discontinuities. The interests of physicists transmogrify into those of chemists, those of chemists into those of biologists, and so on. The lines, the divisions, between departments have been created out of administrative, not intellectual, necessity.
For example, consider the divide between chemistry and biology. There is a set of chemical processes that are characteristic of living systems. Is the study of these processes chemistry or biology? This is a meaningless question. To be …

Phonological Intervention Using A Multiple Opposition Approach, A. Lynn Williams, John Kalbfleisch

ETSU Faculty Works

The purpose of this investigation was to examine phonological restructuring when contrastive oppositions were constructed to include larger treatment sets that confronted the child with multiple sound targets selected from an entire rule set.

The Relationship Between Income And The Ability To Follow The Prescribed Medication Plan In Elderly Persons With Heart Failure, Lori Houghton-Rahrig

Masters Theses

The purpose of this study was to determine if there was a relationship between income, and obtaining and taking of medications as prescribed. The conceptual framework used for this study was Madeleine Leininger's cultural care diversity and universality theory. This secondary analysis used the initial data from the primary study. “ Home Care Outcomes for Heart Failure: A Test of Two Nursing Approaches" (Kline, 1999). A convenience sample of 70 home care clients with heart failure were interviewed using a Likert scale format. A non-parametric correlation using Spearman’s rho depicted a weak relationship between annual income and taking the medication …

The Effect Of Supportive-Educative Nursing Interventions On The Hospital Readmission Rates Of Patients With Heart Failure, Patrice M. Whitaker

Masters Theses

The prevalence of heart failure (HF) is increasing and patients with HF are frequently readmitted to hospitals soon after discharge, at great cost. Improving self-care and reducing hospitalizations in this group is vital. This study, based on Dorothea Orem’s ( 1995) self-care deficit theory, evaluated supportive-educative vs. placebo nursing interventions. The study results were drawn from a larger longitudinal study done by Dr. Kay Setter-Kline, Ph.D., R.N.

The study sought to determine if supportive-educative nursing interventions reduced the rehospitalization rate for patients with HF. The Self-Management Tool was utilized for data collection, after being adapted from the Chronic Disease Self-Management …

School Nurses Asthma Knowledge And Management, Roles And Functions, Carolyn Levi

Masters Theses

The purpose of this study was to explore school nurses’ asthma knowledge, and how they implemented their clinical practice within the school setting. The study also examined the role and functions of the school nurse to compare for continuity. This study examines the relationship of school nurses’ educational level and length of experience upon asthma knowledge.

A self-report survey design was used to collect data. Instrument modification was initiated prior to use. The theoretical basis for this study was the Neuman Systems Model. Results were analyzed in order to investigate relationships and findings. The findings of this study showed no …

The Global Health Corps: Bringing The Power Of Prevention To The People, Michele Yehieli

International Journal of Global Health

The Global Health Corps is now recognized as a model program for improving the cultural competency of health related pre-professionals, and recently received $1,000,000 of federal funding through the U.S. Health Resources and Services Administration fix its operations. It is also the winner of the 1999 Governor's Award for Excellence in Diversity Programming from the state of Iowa, and the Human Rights Award for Black Hawk County, Iowa. Amazingly, in just a few years time, the Global Health Corps has already trained nearly 200 students and served more than 10,000 at risk clients around the world. Through their efforts, students …

Divorce : A Guide For Counselors Assisting Children Of Divorce, Roxann R. Scheffert

Graduate Research Papers

Clinicians must be aware of the presenting problems of children of divorce and effective techniques and interventions when working with this targeted population. The purpose of this paper was to provide various interventions and practical guidelines when working with children of divorce.

The Concentration Of Three Anti-Seizure Medications In Hair: The Effects Of Hair Color, Controlling For Dose And Age, Tom Mieczkowski, Aristidis M. Tsatsakis, Michael Kruger, Thanasis Psillakis

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

This paper assess the relationship between the quantity of three anti-seizure medications in hair and the color of the analyzed hair, while controlling for the effects of dose, dose duration, and patient age for 140 clinical patients undergoing anti-seizure therapy. Three drugs are assessed: carbamazepine (40 patients), valproic acid (40 patients), and phenytoin (60 patients). The relationship between hair assay results, hair color, dose, dose duration, and age is modeled using an analysis of covariance. The covariance model posits the hair assay results as the dependent variable, the hair color as the qualitative categorical independent variable, and dose, …

Review Of Gale Encyclopedia Of Alternative Medicine, John Stephen Brantley

Faculty & Staff Research & Creative Activity

No abstract provided.

Review Of Handbook Of Hypnotic Inductions, John Stephen Brantley

Faculty & Staff Research & Creative Activity

No abstract provided.

Department Of Veterinary And Biomedical Sciences: 2001 Annual Report, John A. Schmitz

School of Veterinary and Biomedical Sciences: Information and History

Twenty Departmental students completed their Bachelor of Science in Agricultural Science degrees in 2001, nineteen in the Veterinary Science Major and one in the Veterinary Technologist Major. Twenty-five Nebraska residents were admitted into the College of Veterinary Medicine at Kansas State University, twelve of them having completed all or part of their pre-veterinary studies at UNL. Seven students completed their Master of Science degree in Veterinary Science. Enrollment in the Distance Education MS in Veterinary Science Master of Science, Distance Education Program increased to seven students, with several applications still being processed or expected. Three new Distance Education courses were …

Borrelia Lonestari Infection After A Bite By An Amblyomma Americanum Tick, Angela M. James, Dionysios Liveris, Gary P. Wormser, Ira Schwartz, Marisa A. Montecalvo, Barbara J. B. Johnson

United States Public Health Resources

Erythematous rashes that are suggestive of early Lyme disease have been associated with the bite of Amblyomma americanum ticks, particularly in the southern United States. However, Borrelia burgdorferi, the causative agent of Lyme disease, has not been cultured from skin biopsy specimens from these patients, and diagnostic serum antibodies usually have not been found. Borrelia lonestari sp nov, an uncultured spirochete, has been detected in A. americanum ticks by DNA amplification techniques, but its role in human illness is unknown. We observed erythema migrans in a patient with an attached A. americanum tick. DNA amplification of the flagellin gene …

The Unequal Cancer Burden: Efforts Of The Centers For Disease Control And Prevention To Bridge The Gap Through Public Health, Nancy C. Lee

United States Public Health Resources

Despite the broad advances made in cancer research and interventions in the last quarter of a century, inequality still persists as we confront challenges arising from the unequal burden of cancer among Americans. Some racial and ethnic minorities, people with low incomes, those in rural areas, and other medically underserved populations suffer disproportionately from cancer. We know, for example, that African Americans are about 34% more likely to die of cancer than whites and more than two times more likely to die of cancer than Asian/Pacific Islanders, American Indians, or Hispanics.

Disparities also exist among the major racial and ethnic …

Helmet Laws And Motorcycle Rider Death Rates, Charles C. Branas, M. Margaret Knudson

United States Public Health Resources

We investigated motorcycle rider death rates between states with full motorcycle helmet laws and those without. This was done using both unadjusted bivariate analyses and multivariate random-effects generalized least squares regression models of rider death rates. Multivariate models were adjusted for the competing influences of several explanatory variables, including the existence of a motorcycle helmet law. From 1994 to 1996, states with helmet laws experienced a median death rate of 6.20 riders per 10 000 registered motorcycles and states without helmet laws experienced a median death rate of 5.07 riders per 10 000 registered motorcycles (P=0.008). After controlling for other …

Evidence For Nonacetylcholinesterase Targets Of Organophosphorus Nerve Agent: Supersensitivity Of Acetylcholinesterase Knockout Mouse To Vx Lethality, Ellen G. Duysen, Bin Li, Weihua Xie, Lawrence M. Schopfer, Robert S. Anderson, Clarence A. Broomfield, Oksana Lockridge

United States Public Health Resources

The possibility that organophosphate toxicity is due to inhibition of targets other than acetylcholinesterase (AChE, EC 3.1.1.7) was examined in AChE knockout mice. Mice (34–55 days old) were grouped for this study, after it was determined that AChE, butyrylcholinesterase (BChE), and carboxylesterase activities had reached stable values by this age. Mice with 0, 50, or 100% AChE activity were treated subcutaneously with the nerve agent VX. The LD₅₀ for VX was 10 to 12 µg/kg in AChE-/-, 17 µg/kg in AChE+/-, and 24 µg/kg in AChE+/- mice. The same cholinergic signs of toxicity were present in AChE-/- mice as …

Characterization Of Immunoglobulin Binding To Isolated Human Erythrocyte Membranes: Evidence For Selective, Temperature-Induced Binding Of Naturally Occurring Autoantibodies To The Cytoskeleton, James M. Salhany, Karen S. Cordes, Renee L. Sloan

United States Public Health Resources

Human plasma contains naturally occurring autoantibodies to the predominant components of the erythrocyte membrane: band 3 and spectrin bands 1 and 2 of the cytoskeleton. The titer of cytoskeletal plasma autoantibodies increases in various hemolytic conditions, suggesting that opsonization of the cytoskeleton may play an important role in the clearance of hemolyzed (not senescent) erythrocytes from the circulation. In this study, we use Alexa Fluor 488 goat anti-human IgG conjugate (Molecular Probes, Eugene, OR, USA), to characterize plasma immunoglobulin binding to erythrocyte membranes from osmotically hemolyzed cells (`ghosts'). The results show that exposure of ghosts to plasma results in 4-fold …

Context-Dependent Memory Under Stressful Conditions: The Case Of Skydiving, Laura A. Thompson, Keith L. Williams, Paul R. L'Esperance, Jerffrey Cornelius

Faculty Publications - College of Nursing

Two experiments examined the effect of differing levels of emotional arousal on learning and memory for words in matching and mismatching contexts. In Experiment 1, experienced skydivers learned words either in the air or on the ground and recalled them in the same context or in the other context. Experiment 2 replicated the stimuli and design of the first experiment except that participants were shown a skydiving video in lieu of skydiving. Recall was poor in air-learning conditions with actual skydiving, but when lists were learned on land, recall was higher in the matching context than in the mismatching context. …

Nurse Manager As Leader: Creating Community Within A Healthcare Organization, Theresa Marie Duffy

Theses and Graduate Projects

Healthcare organizations are searching for mechanisms that will encourage the employ and retention of skilled registered nurses. Traditional management styles have done little to create a nurturing and supportive workplace that encourages staff nurses to work in an inpatient setting. A non-traditional nurse manager as a leader, who exhibits relational and servant-leadership characteristics can facilitate a process of creating a workplace community with registered nurses that will not only provide a supportive environment, but will perform better as well. This paper explores the attributes of a non-traditional nurse manager that will promote the development of a workplace cornrnunity.

Bovine Tuberculosis In Free-Ranging Carnivores From Michigan, Colleen S. Bruning-Fann, Stephen M. Schmitt, Scott D. Fitzgerald, Jean S. Fierke, Paul D. Friedrich, John B. Kaneene, Kathy A. Clarke, Kelly L. Butler, Janet B. Payeur, Diana L. Whipple, Thomas M. Cooley, Janice M. Miller, Darian P. Muzo

Michigan Bovine Tuberculosis Bibliography and Database

During a survey of carnivores and omnivores for bovine tuberculosis conducted in Michigan (USA) since 1996, Mycobacterium bovis was cultured from lymph nodes pooled from six coyotes (Canis latrans) (four adult female, two adult male), two adult male raccoons (Procyon lotor), one adult male red fox (Vulpes vulpes), and one 1.5-yr-old male black bear (Ursus americanus). One adult, male bobcat (Felis rufus) with histologic lesions suggestive of tuberculosis was negative on culture but positive for organisms belonging to the Mycobacterium tuberculosis complex when tested by polymerase chain reaction. All the …

Evaluation Of Florida’S Sub-Acute Inpatient Psychiatric Program (Sipp), Kristen M. Snyder, Angela Gomez, Mary L. Armstrong, Kathy Thompson-Dailey, Tom Massey

Mental Health Law & Policy Faculty Publications

In March 1998, the State of Florida received approval of a 1915 (b) waiver from the Health Care Financing Administration (HCFA) to implement an alternative, Sub-acute Inpatient Psychiatric Program (SIPP) for children under the age of 18, who had two or more psychiatric inpatient stays in a year, or a length of stay greater than thirteen days. For these high risk youth, who were typically served in general hospitals, the SIPP model was designed to improve the transition from inpatient care to community based care, in an effort to reduce the high rates of readmission and improve their chances of …

Research Across Multiple Systems: Probabilistic Population Estimation (Ppe), Diane Haynes, Rebecca Larsen, Shabnam Mehra

Mental Health Law & Policy Faculty Publications

Today, social service administrators are examining client service utilization using cross system analysis, because often a client's needs require accessing governmentfunded services from multiple organizations. One technical problem that arises is that organizations do not share common unique identifiers from which to link one individual’s information together (i.e., system #1 uses Social Security Number (SSN) and system #2 uses Personal Identification Number (PIN)). Different methods have been employed to deal with the issue of working with information across data sets when there is no common unique identifier. Probabilistic Population Estimation (PPE), Caseload Segregation/Integration Ratio (C/SIR), and Probabilistic Population Matching (PPM) …

Bulletin 4474 - Exotic Diseases - Horses, Agriculture Western Australia

Bulletins 4000 -

An exotic disease is a disease that is not present in Australia.

If an exotic disease did occur in Australia it would cause production losses, stock deaths and stop exports of primary production. When export markets are lost they can only be re-established once it is proven the disease is eradicated.

The Regulation Of Manganese Superoxide Dismutase And Inducible Nitric Oxide Synthase By Nuclear Factor-Kappa B And Activator Protein 1 In Rat Aortic Endothelial Cells, Scott L. Cobbs

Theses, Dissertations and Capstones

Inducible nitric oxide synthase (iNOS) and manganese superoxide dismutase (MnSOD) are two enzymes that influence reactive oxygen species within the cell. The promoter regions for the genes encoding these enzymes have two specific transcription factor elements in common, activator protein 1 (AP-1) and nuclear factor kappa b (NF-KB). This study was initiated to determine if either NF-KB or AP-1 regulates the transcription of both genes in endothelial cells. To test whether NF-KB or AP-1 binding sites in the MnSOD and iNOS promoter region were important for transcriptional regulation, we performed induction analysis using various deletion constructs of MnSOD and iNOS …

Transitions To Adulthood In The Context Of Aids In South Africa: Report Of Wave I, Naomi Rutenberg, Cathrien Kehus-Alons, Lisanne Brown, Kate Macintyre, Anthea Dallimore, Carol E. Kaufman

HIV and AIDS

This is a prospective study of reproductive behavior and sexual health of adolescents in South Africa as well as their education and employment experiences, family and environmental conditions, and other factors in their lives that may influence their sexual behavior and choices. This report is designed to inform educators, policymakers, and the public in South Africa and beyond of the initial findings of the study, with the ultimate goal of helping to design and refine policies and programs that will improve opportunities and capacities of adolescents and may contribute to changing behaviors and choices. The report focuses on describing the …

Prevention Of Trafficking And The Care And Support Of Trafficked Persons In The Context Of An Emerging Hiv/Aids Epidemic In Nepal, Celine Daly

HIV and AIDS

This study is a collaborative effort between the Asia Foundation (Kathmandu) and the Horizons project of the Population Council (New Delhi) to document the current intervention models and community-based study of human trafficking in the context of an emerging HIV/AIDS epidemic in Nepal. To address the human rights component of trafficking, the three components of this study focus on the rights and needs of trafficked persons as well as those who are vulnerable to trafficking. An analysis and assessment of the effectiveness of laws, policies, and interventions in the apprehension, prosecution, and conviction of alleged traffickers is not included in …