Medicine and Health Sciences Commons^™

Ua66/4/2 Ceremony Of Capping & Pinning, Wku Dental Hygiene

WKU Administration Documents

Program from capping & pinning ceremony.

Virtue And The Health Professions, Janet Pisaneschi

Center for the Study of Ethics in Society Papers

Presented to the WMU Center for the Study of Ethics in Society, February 8, 1991.

Information Interface - Volume 15, Issue 3 - May/June 1991, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

The Calendar - May 1991, Nova University

The Calendar

No abstract provided.

Interleukin-2-Triggered Raf-1 Expression, Phosphorylation, And Associated Kinase Activity Increase Through G1 And S In Cd3-Stimulated Primary Human T Cells., Antanina Zmuidzinas, Harvey J. Mamon, Thomas M. Roberts, Kendall A. Smith

Dartmouth Scholarship

To gain further insight into the role of Raf-1 in normal cell growth, c-raf-1 mRNA expression, Raf-1 protein production, and Raf-1-associated kinase activity in normal human T cells were analyzed. In contrast to the constitutive expression of Raf-1 in continuously proliferating cell lines, c-raf-1 mRNA and Raf-1 protein levels were barely detectable in freshly isolated G0 T lymphocytes. Previous work with fibroblasts has suggested that Raf-1 plays a signaling role in the G0-G1 phase transition. In T cells, triggering via the T-cell antigen receptor (TCR)-CD3 complex (TCR/CD3) resulted in an approximately fourfold increase in c-raf-1 mRNA. In addition, the promotion …

Reaction Of Chromium(Vi) With Glutathione Or With Hydrogen Peroxide: Identification Of Reactive Intermediates And Their Role In Chromium(Vi)-Induced Dna Damage, J Aiyar, H Berkovits, R Floyd, K Wetterhahn

Dartmouth Scholarship

The types of reactive intermediates generated upon reduction of chromium(VI) by glutathione or hydrogen peroxide and the resulting DNA damage have been determined. In vitro, reaction of chromium(VI) with glutathione led to formation of two chromium(V) complexes and the glutathione thiyl radical. When chromium(VI) was reacted with DNA in the presence of glutathione, chromium-DNA adducts were obtained, with no DNA strand breakage. The level of chromium-DNA adduct formation correlated with chromium(V) formation. Reaction of chromium(VI) with hydrogen peroxide led to formation of hydroxyl radical. No chromium(V) was detectable at 24 degrees C (297 K); however, low levels of the tetraperoxochromium(V) …

Student Attitudes Toward Their Role As Patient Advocate, Jacquelyn Heinlein Graven

Honors Projects

Patient advocacy is a role which has been identified as an important one for nurses. Numerous definitions, models, opinions and philosophical justification of advocacy as a nursing role are described in the literature. The importance of this role is obvious when considering the philosophical dimensions of advocacy. It has been suggested that the concept of advocacy may be the fundamental or theoretical foundation of nursing (Donahue, 1985; Gadow, 1980). Although the role has been discussed for many years there are few established guidelines for implementation and little research exists regarding the advocacy role. The purpose of this descriptive study is …

Les Accidents Aux Mains Dans Le Secteur De La Fabrication De Produits En Métal, Danièle Champoux, Madeleine Bourdouxhe

Rapports de recherche scientifique

No abstract provided.

Evidence For Attenuation Of Myo-Inositol Uptake, Phosphoinositide Turnover And Inositol Phosphate Production In Aortic Vasculature Of Rats During Pregnancy, Kirk P. Conrad, Susan A. Barrera, Peter A. Friedman, Vicki M. Schmidt

Dartmouth Scholarship

We postulated that vascular phosphoinositide metabolism is attenuated during pregnancy, and thereby could contribute to maternal vasodilation and reduced vascular reactivity. The basal rate of incorporation of [3H]myo-inositol and [3H]glycerol into phosphoinositides of aortae from pregnant rats in vitro was significantly reduced, when compared with vessels from virgin animals. After injection of [3H]myo-inositol intravenously into chronically instrumented conscious pregnant and virgin rats, the incorporation of the label by phosphatidylinositol was 66 +/- 4% less in aortae of gravid versus virgin animals (P less than 0.001), despite comparable plasma concentrations of radioactivity. Fold stimulation of total [3H]inositol phosphates by arginine vasopressin, …

Efficient Immortalization Of Luminal Epithelial Cells From Human Mammary Gland By Introduction Of Simian Virus 40 Large Tumor Antigen With A Recombinant Retrovirus, Bartek J, Bartkova J, Kyprianou N, El-Nasir Lalani, Staskova Z, Shearer M, Chang S, Taylor Papadimitriou J

Department of Pathology and Laboratory Medicine

When defined in terms of markers for normal cell lineages, most invasive breast cancer cells correspond to the phenotype of the common luminal epithelial cell found in the terminal ductal lobular units. Luminal epithelial cells cultured from milk, which have limited proliferative potential, have now been immortalized by introducing the gene encoding simian virus 40 large tumor (T) antigen. Infection with a recombinant retrovirus proved to be 50-100 times more efficient than calcium phosphate transfection, and of the 17 cell lines isolated, only 5 passed through a crisis period as characterized by cessation of growth. When characterized by immunohistochemical staining …

Ua12/2/1 Magazine, Wku Student Affairs

WKU Administration Documents

Special magazine edition of the College Heights Herald:

• Howard, Laura. Lessons in Patience – Patrick Petty, Panorama

Novel Peptidyl Carbamate Inhibitors Of The Enzyme Elastase, George A. Digenis, Bushra J. Agha

Pharmaceutical Sciences Faculty Patents

To see the abstract, please download this patent.

The Relationships Among Competitive Orientation, Sport-Confidence, Self-Efficacy, Anxiety, And Performance, Jeffrey J. Martin, Diane L. Gill

Kinesiology, Health and Sport Studies

We examined the relationships among trait and state psychological variables and performance in male high school distance runners using the Sport Orientation Questionnaire (SOQ; Gill & Deeter, 1988), the Competitive Orientation Inventory (COI; Vealey, 1986), the Trait Sport-Confidence Inventory (TSCI; Vealey, 1986), the State Sport-Confidence Inventory (SSCI; Vealey, 1986), the Competitive State Anxiety Inventory-2 (CSAI-2; Martens, Burton, Vealey, Bump & Smith, 1990), and separate self-efficacy scales for performance (time) and outcome (place). As hypothesized, trait sport-confidence predicted state sport-confidence and outcome self-efficacy. However, competitive orientation did not contribute to the prediction of state measures. State sport-confidence and self-efficacy predicted performance, …

Strain-Specific Neutralizing Determinant In The Transmembrane Protein Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Daniel P. Silva, Fulvia Dimarzo Veronese, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

Monoclonal antibody SF8/5E11, which recognizes the transmembrane protein (TMP) of simian immunodeficiency virus of macaque monkeys (SIVmac), displayed strict strain specificity. It reacted with cloned and uncloned SIVmac251 but not with cloned SIVmac142 and SIVmac239 on immunoblots. This monoclonal antibody neutralized infection by cloned, cell-free SIVmac251 and inhibited formation of syncytia by cloned SIVmac251-infected cells; these activities were specific to cloned SIVmac251 and did not occur with the other viruses. Site-specific mutagenesis was used to show that TMP amino acids 106 to 110 (Asp-Trp-Asn-Asn-Asp) determined the strain specificity of the monoclonal antibody. This strain-specific neutralizing determinant is located within a …

Evaluation Of Four Aerobiological Sampling Methods For The Retrieval Of Aerosolized Pseudomonas Syringae, Mark P. Buttner, Linda Stetzenbach

Environmental & Global Health Faculty Research

The Andersen six-stage impactor, the SAS (Surface Air System) impactor, the AGI-30 impinger, and gravity plates were evaluated for the retrieval of aerosol-releasedPseudomonas syringae. The upper limits of the impactor samplers were exceeded at a spray concentration of 10^7 CFU/ml, indicating that these samplers are not appropriate for monitoring high airborne concentrations. Decreased cell concentrations were retrieved with increased sampling time for the Andersen and AGI samplers, indicating that a minimum sampling time is preferable for monitoring aerosolized vegetative cells.

Ua61/1 Wku Nursing Class 1991, Wku Nursing

WKU Administration Documents

Members of the 1991 nursing class: Patricia Sanchez, Lyndi Squires, Sherri Thomas, Lori Radford, Jean Atwell, Laura Tuck, Robbie Ghafoori, Susan Bolts, Darren Lawrence, Angela Fields, Marla Thompson, Rebecca Hall, Debra Cain, Karen Creasy, Sheila Howard-Tomes, Audra Lesnansky, Christy Wood, Katherine Winkler, Debra Coates, Sandy Small, David Smith, Shannon Martin, Tracy Lewis, Gwen Turner, Nicholle McDonald, Cathy Duke-Hodgkins, Darlene Dakin, Yvonne Caffee, Laura Skala, Jeff Jones, Sandra Tidwell, Laura Simmons, Gayle Brown, Lisa Chikhard, Jill Askins, Julie Dansby, Gina Haynes, Jennifer Rogers, Kelley Conquest, Elaine Pursell, Betty Crabtree, Amy Hale, Bill McDonald, Leslie Bradshaw and Sheila Houchins.

The Calendar - April 1991, Nova University

The Calendar

No abstract provided.

Selection Of Genetic Variants Of Simian Immunodeficiency Virus In Persistently Infected Rhesus Monkeys, Dawn P. Wooley, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

Genetic and antigenic variation may be one means by which lentiviruses that cause AIDS avoid elimination by host immune responses. Genetic variation in the envelope gene (env) was studied by comparing the nucleotide sequences of 27 clones obtained from two rhesus monkeys infected with molecularly cloned simian immunodeficiency virus. All 27 clones differed from each other and differed from the input clone in the gp120 (SU) portion of the envelope gene. Nucleotide substitutions were shown to accumulate with time at an average rate of 8.5 per 1,000 per year in SU. Surprisingly, the majority of nucleotide substitutions (81%) resulted in …

Tympanic Infrared Thermometry For Fullterm And Preterm Neonates, Marianne E. Weiss

College of Nursing Faculty Research and Publications

Tympanic infrared thermometry has been proposed as a safe, rapid, cost-effective, and reliable method of temperature taking. 1,2 Testing with adults and children have produced results supporting its use in clinical practice. In previous studies conducted with an adult population, excellent results for accuracy and precision were obtained.^3,4 Studies of children have primarily focused on the use of tympanic thermometry for use in pediatric office and emergency room settings.^5~6 Kenney et al.1 found tympanic thermometry to differ from rectal temperature by .06°C across all ages and by .02°C for subjects less than two months of age. Mean differences …

An Emerging Leadership Paradigm: Transformational Leadership, Anne M. Barker

Nursing Faculty Publications

Transformational leadership is the "in" label. But what does it mean? Why is it becoming popular? Barker tells us that in an era when hierarchies and their rules are breaking down, the inspirational leader who empowers workers is needed.

Jefferson Alumni Bulletin – Volume Xl, Number 3, Spring 1991

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XL, Number 3, Spring 1991 Growth and maturation of the pediatrics department, page 2 The Virgin Islands’ response to hurricane Hugo, page 10 Obstacles to care in a troubled land, page 14 Romanian rehabilitation, page 15 On campus, page 16 Class notes, page 23

Multinational Validation Of Anxiety, Hopelessness, And Ineffective Airway Clearance, Richard J. Fehring, Teresa Fadden, Madeline Wake

College of Nursing Faculty Research and Publications

The effective use of nursing diagnosis internationally depends in part on incorporating language and cultural difference into the common language of nursing. International validation studies can provide a basis for this effort. This study tested three diagnoses—anxiety, hopelessness, and ineffective airway clearance—through multinational validation. The Diagnostic Content Validity (DCV) model was used to collect data from critical care nurses in six countries. Defining characteristics rated as critical (> .80) by the total sample were dyspnea for ineffective airway clearance and panic and nervousness for anxiety. No critical defining characteristics for hopelessness were identified. DCV ratios for …

Ua12/2/1 Magazine, Wku Student Affairs

WKU Administration Documents

Special magazine edition of the College Heights Herald:

• Poore, Chris. Silent Escape – Amy Deputy, Bulimia

Personality And Socialization Correlates Of Vicarious Emotional Responding, Nancy Eisenberg, Richard Fabes, Mark Schaller, Paul Miller, Gustavo Carlo, Rick Poulin, Cindy Shea, Rita Shell

Department of Psychology: Faculty Publications

The relations of personality and family characteristics to adults’ negative vicarious emotional responses to sympathy and distress films were examined. Ss reported more sympathy and less personal distress and exhibited less skin conductance as well as heart rate deceleration when viewing a sympathy-evoking film. Dispositional emotional intensity and fantasy empathy were associated with greater self-reported emotional responding and higher skin conductance. Dispositional perspective taking and personal distress were positively and negatively correlated, respectively, with reported vicarious responding to the sympathy film when Ss were administered instructions to imagine the emotions of those in the films. Family cohesiveness was associated with …

The Altruistic Personality: In What Contexts Is It Apparent?, Gustavo Carlo, Nancy Eisenberg, Debra Troyer, Galen Switzer, Anna L. Speer

Department of Psychology: Faculty Publications

Hypotheses concerning the specific contexts in which an altruistic personality might be most apparent were investigated, College students completed questionnaires tapping components of an altruistic personality, emotionality, and social desirability. At a 2nd session, the emotional evocativeness and ease of escape from the helping situation were experimentally manipulated. Ss were exposed to a distressed woman, completed state sympathy and personal distress indexes, and were given an opportunity to assist the woman. High scorers on dispositional altruism were expected to assist most when escape was easy, particularly when the distress cues were obvious. Altruistic and emotionally reactive persons were also expected …

Information Interface - Volume 15, Issue 2 - March/April 1991, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

The Calendar - March 1991, Nova University

The Calendar

No abstract provided.

Epidural Spinal Cord Compression From Metastatic Cancer: Clinical Features And Management, H Shaheen, S Abubakar, I Malik, I Altafullah, F Alam, A Khan

Section of Nephrology

We retrospectively analyzed thirty-three patients (21 males, 12 females) with malignancy induced spinal cord compression (SCC). The mean age of the patients was 42.8 years and almost half (51%) of them presented with SCC. Mean duration of symptoms was 4.5 months and the mean interval between the original diagnosis of cancer and the development of SCC was 14.6 months. Back pain was the most frequent (97%) symptom with an equal number of patients having subjective or objective evidence of lower limb weakness. Majority (73%) of the patients were non-ambulatory at the time of diagnosis. Spinal level involvement was mostly thoracic …

Acquired Cisplatin Resistance In Human Ovarian Cancer Cells Is Associated With Enhanced Repair Of Cisplatin-Dna Lesions And Reduced Drug Accumulation., Ricardo J. Parker, Alan Eastman, Frieda Bostick-Bruton, Eddie Reed

Dartmouth Scholarship

Studies were undertaken to investigate acquired resistance to cisplatin in human ovarian cancer cells. The cell lines A2780 and A2780/CP70 were studied to assess their respective characteristics of drug accumulation and efflux, cytosolic inactivation of drug, and DNA repair. All experiments were performed using 1-h drug exposures. The A2780/CP70 cell line was 13-fold more resistant to cisplatin than A2780 cells. When studied at their respective IC50 doses, drug accumulation rates were similar for the two cell lines. However, the resistant cell line was twofold more efficient at effluxing drug, which was associated with reduced total drug accumulation for equivalent micromolar …

The Right To Die: An Old Woman's Formula, Mary Guinan

School of Public Health Faculty Research

On December 26, 1990, Nancy Cruzan died, 12 days after her feeding tube was removed. She had been in an irreversible coma for seven years and her parents had sued for the right to remove the feeding tube that was keeping her alive. The pain and suffering of her family in coming to this decision was certainly compounded by those who disagreed with them and tried to prevent the extubation. Whether one agrees with this particular decision or not, most of us will not be faced with such clear alternatives, ie, leave the tube in or take it out in …