Medicine and Health Sciences Commons^™

Étude De La Problématique Des Maux De Dos Dans Le Secteur Minier Québécois, Renée Levaque Charron, Suzanne Gingras, Michel Vézina

Rapports de recherche scientifique

No abstract provided.

Étude Sur La Validité De Matrices Emploi-Exposition Multisectorielles En Hygiène Industrielle, Michel Gérin, Louise De Guire, Jack Siemiatycki

Rapports de recherche scientifique

No abstract provided.

Intégration De L'Ergonomie Au Processus De Conception D'Une Usine D'Abattage De Volailles, Jean-Guy Richard, Marie Bellemare

Rapports de recherche scientifique

No abstract provided.

L'Absorption Percutanée Des Contaminants Du Milieu De Travail, Claude Viau, Diane Talbot, Adolf Vyskocil

Rapports de recherche scientifique

No abstract provided.

Étude Descriptive Des Déterminants Des Facteurs De Risque De Latr Aux Postes D'Éviscération Abdominale De Deux Abattoirs De Porcs, Georges Toulouse, Nicole Vézina, Lucie Geoffrion

Rapports de recherche scientifique

No abstract provided.

Impact Of Spinal Cord Injury On The Life Roles Of Women., M Claire Quigley

Department of Occupational Therapy Faculty Papers

This qualitative study was conducted to explore and describe the role experience of five women whose lives were disrupted by a traumatic spinal cord injury and who later returned to their communities after completing intensive rehabilitation programs. In-depth interviews and participant observations were used to examine the experiences of these women. The findings exemplify how the women's use of adaptation and negotiation and the development of a new role as self-advocate facilitated the reestablishment of their life roles. As the women's occupational roles were redefined, the processes of adaptation and negotiation were evident in three aspects of their lives: daily …

EnterohemorrhagicEscherichia Coli O157:H7 Requires Intimin To Colonize The Gnotobiotic Pig Intestine And To Adhere To Hep-2 Cells, Marian L. Mckee, Angela R. Melton-Celsa, Rodney A. Moxley, David H. Francis, Alison D. O'Brien

School of Veterinary and Biomedical Sciences: Faculty Publications

In a previous study, enterohemorrhagic Escherichia coli (EHEC) O157:H7 with a deletion and insertion in the eaeA gene encoding intimin was used to establish that intimin is required for the organism to attach to and efface microvilli in the piglet intestine (M. S. Donnenberg, S. Tzipori, M. L. McKee, A. D. O’Brien, J. Alroy, and J. B. Kaper, J. Clin. Invest. 92:1418–1424, 1993). However, in the same investigation, a role for intimin in EHEC adherence to HEp-2 cells could not be definitively demonstrated. To analyze the basis for this discrepancy, we constructed an in-frame deletion of eaeA and compared the …

Identification Of Gene Products Encoded By The Latency-Related Gene Of Bovine Herpesvirus 1, Ashfaque Hossain, L. M. Schang, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine herpesvirus 1 (BHV-1) establishes a latent infection in sensory ganglionic neurons of infected animals. Expression of latency-related (LR) gene products is controlled by a 980-bp fragment (LR promoter). DNA sequence analysis revealed that two major open reading frames (ORFs) are in the LR gene. Antibodies directed against both ORFs were generated in rabbits by using synthetic peptides. Antibody P2, which is directed to sequences near the amino terminus of ORF 2, recognized a 41-kDa protein in lytically infected cells, suggesting that ORF 2 encodes a protein. When the LR gene was inserted into a mammalian expression vector and subsequently …

Jefferson Alumni Bulletin – Volume Xliv, Number 4, September 1995

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLIV, Number 4, September 1995 Anniversary galas, page 4 and 24 Jefferson health system in established by the university and main line health, page 12 Research, page 14 Appointments, page 20 Books, page 22 Journal of neurovirology is founded, page 22

Evaluation Of Oral Midazolam As Pre-Medication In Day Care Surgery In Adult Pakistani Patients, N Ahmed, F A. Khan

Department of Anaesthesia

A placebo controlled randomized double blind study was designed to assess the suitability of oral Midazolam as a premedication in day care surgery in adult Pakistani patients. Fifty ASA I and II patients aged between 20-60 years received either Midazolam 7.5 mg or a placebo approximately one hour prior to surgery. Midazolam 7.5 mg produced significant anxiolysis and sedation (p < 0.001) in comparison to placebo after one hour of premedication. There was a significant difference (p < 0.001) in the mean heart rate and blood pressure in both groups after 1 hour of premedication with a lesser rise in blood pressure and heart rate in the Midazolam group. Psychomotor performance assessed by 'n' deletion test was impaired by Midazolam (p < 0.001) and recall of pictures revealed differences (p < 0.05) in the groups at one hour after premedication. However, at four hours after surgery there were no differences in both groups. These findings indicate that rapidly acting oral Midazolam in doses of 7.5 mg provided safe and effective premedication in terms of anxiolysis, sedation, amnesia and psychomotor performance and is suitable for day surgery.

Anti-Human Immunodeficiency Virus (Hiv) Activities Of Halogenated Gomisin J Derivatives, New Nonnucleoside Inhibitors Of Hiv Type 1 Reverse Transcriptase, Toshiaki Fujihashi, Hiroto Hara, Toshiya Sakata, Kazuya Mori, Hirotaka Higuchi, Akio Tanaka, Hideko Kaji, Akira Kaji

Department of Biochemistry and Molecular Biology Faculty Papers

Halogenated gomisin J (a derivative of lignan compound), represented by the bromine derivative 1506 [(6R, 7S, S-biar)-4,9-dibromo-3,10-dihydroxy-1,2,11,12-tetramethoxy-6, 7-dimethyl-5,6,7,8- tetrahydrodibenzo[a,c]cyclo-octene], was found to be a potent inhibitor of the cytopathic effects of human immunodeficiency virus type 1 (HIV-1) on MT-4 human T cells (50% effective dose, 0.1 to 0.5 microM). Gomisin J derivatives were active in preventing p24 production from acutely HIV-1-infected H9 cells. The selective indices (toxic dose/effective dose) of these compounds were as high as > 300 in some systems. 1506 was active against 3'-azido-3'-deoxythymidine-resistant HIV-1 and acted synergistically with AZT and 2',3'-ddC. 1506 inhibited HIV-1 reverse transcriptase (RT) in …

Farmer Is Run Over By Disc After Falling From Tractor, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

Because access to the scene and inspection of the equipment were not possible in this case, a partial inspection was done. Conclusions cannot be drawn from the evidence collected.

A 68-year-old farmer died when he fell from his tractor into the path of an attached disc. The victim had begun discing a tobacco field about 3:00 p.m., minutes after his wife and son left for second-shift work at a factory. After completing one field, he proceeded to a second field to complete the afternoon's work. The second field was across a small galley. As the victim drove the tractor through …

Apparatus And Method For Multiple Wavelength Of Tissue, Robert A. Lodder, Lisa A. Cassis

Pharmaceutical Sciences Faculty Patents

An apparatus for analyzing the chemical composition of tissue includes a near infrared light source, a fiber-optic probe, a mechanism for directing the light from the light source onto the tissue and detectors for detecting light reflected by the tissue. The light source transmits an incident beam having a wavelength ranging from 1000 to 2500 nm. A compound parabolic concentrator (CPC) is connected to a distal end of the fiber optic probe to focus or concentrate the wavelengths of light simultaneously and in parallel on a particular spot of tissue. Alternatively, an inverted, substantially conical reflector is positioned to scatter …

Farmer Run Over After Falling From Tractor, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 54-year-old male farmer was killed in a tractor runover incident. The victim was on his way to his tobacco field when he lost control of his tractor. After it left the road, he fell and was run over by the right rear tire and possibly the edge of the attached plow. The three-year-old tractor was equipped with a seatbelt, but it was not fastened. The victim was pronounced dead at the scene by the county coroner. In order to prevent similar incidents, the KY FACE investigator concluded that:

• Tractor operators should always wear seatbelts;
• Tractor operators should pay close …

Farmer Killed In Tractor Rollover [95ky039], Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 66-year-old male farmer was killed in a tractor rollover incident. The victim was discing a small tobacco plot near his home when he lost control of his tractor. It went over an embankment, rolled one-half turn and landed on the victim before rolling further down the embankment. It was not equipped with a rollover protective structure (ROPS) or a seatbelt; its brakes were inoperable. The victim was pronounced dead at the scene by the county coroner. In order to prevent similar incidents, the KY FACE investigator concluded that:

• tractors should be retrofitted with Roll Over Protective Structures and seatbelts; …

Farmer Killed After Tractor Overturns Into Creek Bed, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 47-year-old farmer/chemical analyst was killed when his tractor overturned into a muddy creek bed. The victim was checking a fence line on his property, which in that area has a rough, uneven terrain and on that day was very wet from a thunderstorm the previous night. He was going up an incline when his tractor slid backwards in the mud; the back tire slipped over the edge of a steep embankment and the tractor rolled over into the creek bed, pinning him face down in the mud. The tractor was not equipped with a Roll Over Protective Structure (ROPS) …

Information Interface - Volume 20, Issue 3 - August/September 1995, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

The Relationship Between Vision And Athletic Performance, Steven Richard Wininger

Masters Theses & Specialist Projects

In today's competitive world of athletics it is not uncommon to discover a few athletes actively involved in some form of vision enhancement motivated by the promise that the exercises will improve their athletic performance. A review of past and present literature in the area of sports vision revealed that these athletes are performing exercises based upon a very weak scientific foundation. Most of the research investigating the relationship between vision and athletic performance has been plagued by flawed methodology, as well as extremely low numbers of subjects. The purpose of this study was to test for any relationship between …

Antibody Response To Trypanosoma Cruzi During The Course Of Infection In Mice Held At Elevated Environmental Temperature, Lianyong Gao

Masters Theses & Specialist Projects

It has been demonstrated that changes in environmental temperature can influence the resistance of mice to Trypanosoma cruzi (the causative agent of Chagas' disease in humans) infection. This increased resistance is not only reflected by decreased parasitemias and increased longevity but also by enhanced parasite-specific and nonspecific immune responsiveness in infected mice. The antibody response to heterologous antigen has been demonstrated to be greatly enhanced in infected mice held at elevated temperature. However, the parasite-specific antibody response was reported to be lower in infected mice maintained at 36°C than at room temperature (RT) during early stage of infection, although it …

The Effect Of Dietary Supplemented Vitamin E And Selenium On Experimental Chagas' Disease, Brenda Bennett

Masters Theses & Specialist Projects

Dietary supplementation with increased levels of vitamin E can enhance the immune system of C3HeB/FeJ mice to enable many of them to survive an otherwise lethal dose of Trypanosoma cruzi, the causative agent of Chagas' disease. To study the role of diet on the course of experimental Chagas' disease, C3HeB/FeJ mice were fed pelleted, synthetic food containing no vitamin E and selenium, 800 IU/kg vitamin E, 2 ppm selenium, or food containing 800 IU/kg vitamin E plus 2 ppm selenium. Mice on synthetic food were compared to control mice fed a commonly used Purina rodent chow # 5001. After diet …

Animal Activist Urges Vets To Be Activists Too, Henry Spira

Commentaries and Editorials

No abstract provided.

Site Directed Mutagenesis Of A Putative Protease Cleavage Site Within The 105 Kilodation Protein Of Southern Bean Mosaic Virus, Jingyu Shi

Masters Theses & Specialist Projects

There are four open reading frames (ORF) in three positive-sense translational phases of Southern Bean Mosaic Virus (SBMV). ORF2 codes for a 105 KDa polyprotein which is proposed to be autocatalytically cleaved into smaller functional proteins. Amino acid sequence homology between the SBMV and poliovirus, foot and mouth disease virus, and cowpea mosaic virus reveal that SBMV has a similar genomic organization to picornaviruses with a conserved order: Vpg (Viral protein, genome-linked )-protease-replicase. Two Gln-Ser (QS) amino acid pairs within the 105 KDa polyprotein, C75= 930-936, C60= 1305-1310, are proposed to be the cleavage sites based on 1) similar structural …

Military Recreation Programs: Their Role In Quality Of Life Of United States' Service Men And Women And Their Families, Michael Gorham

Masters Theses & Specialist Projects

This thesis was designed to determine the importance of military recreation programs in improving the quality of life of United States service men and women. The study utilized a survey conducted on Fort Campbell, Kentucky, in the Spring of 1995. The results were analyzed individually and as a group. The findings were that military recreation programs play an important role in the quality of life of United States service men and women and their families. These findings were supported by the review of related literature and results from the survey which showed that 70% of the respondent's "Agreed" or "Strongly …

Race, Family, And Obligation, Rodney C. Roberts

Center for the Study of Ethics in Society Papers

The Martin Luther King Jr. Day Lecture Presented to the WMU Center for the Study of Ethics in Society, January 16, 1995.

The Effect Of A Shared Decisionmaking Program On Rates Of Surgery For Benign Prostatic Hyperplasia. Pilot Results., John E. Wennberg

Dartmouth Scholarship

Mulley at al hypothesized that active efforts to involve patients in devisions made about their care should improve outcomes by better matching treatments with patient values and needs. How utilization of various treatments would be affected is a critical element of the evaluation of such efforts. The Shared Decisionmaking Program for benign prostatic hyperplasia (SDP-BPH) is an interactive videodisc-based patient education program designed to help patients make an informed choice about whether to elect a transurethral resection of the prostate (TURP) or to follow a program of expectant management called "watchful waiting."

The BPH-SDP was piloted by two urology groups …

Patient Reactions To A Program Designed To Facilitate Patient Participation In Treatment Decision For Benign Prostatic Hyperplasia, John E. Wennberg

Dartmouth Scholarship

Patients often want considerable information about their conditions, and enhanced patient participation might reduce unwanted practice variation aad improve medical decisions. The authors assessed how men with benign prostatic hyperplasia reacted to an educational program designed to facilitate participation in declsionmaking and how strongly ratings of their symptom state and the prospect of complications predicted their treatment choice. A prospective cohort study was conducted in three hospital-based urology practices: two in prepaid group practices, and one Veterans Administration clinic. Four hundred twenty-one men with symptomatic benign prostatic hyperplasia without prior prostatectomy or benign prostatic hyperplasia complication were enrolled, and 373 …

Transactivation Of The Moloney Murine Leukemia Virus And T-Cell Receptor Beta-Chain Enhancers By Cbf And Ets Requires Intact Binding Sites For Both Proteins., Wanwen Sun, Barbara J. Graves, Nancy A. Speck

Dartmouth Scholarship

The Moloney murine leukemia virus (Mo-MLV) enhancer contains binding sites (LVb and LVc) for the ets gene family of proteins and a core site that binds the polyomavirus enhancer-binding protein 2/core-binding factor (cbf) family of proteins. The LVb and core sites in the Mo-MLV enhancer contribute to its constitutive activity in T cells. All three binding sites (LVb, LVc, and core) are required for phorbol ester inducibility of the Mo-MLV enhancer. Adjacent binding sites for the ets and cbf proteins likewise constitute a phorbol ester response element within the human T-cell receptor beta-chain (TCR beta) enhancer and contribute to constitutive …

The Dmpa Service Provider: Profile, Problems And Prospects—Philippines, Maria Carmela Patron, Marilou P. Costello

Reproductive Health

This report presents the results of interviews conducted with 60 trained DMPA service providers from seven of the ten local government units (LGUs) covered by Phase I of the Philippine Department of Health's DMPA Reintroduction Program. DMPA, or Depot-medroxyprogesterone acetate, is an injectable contraceptive commonly known as Depo-Provera. The interviews were undertaken as part of the DMPA Monitoring and Follow-up Studies sponsored by the Population Council under the Asia and Near East Operations Research and Technical Assistance (ANE OR/TA) Project. While the monitoring study and the follow-up survey focused on DMPA users and dropouts, this study centered on the service …

Research To Practice: Consumer And Family Perspectives On The Meaning Of Work, Sheila Fesko

Research to Practice Series, Institute for Community Inclusion

Findings from a study that obtained the perspectives of people with significant disabilities and their family members about their employment experiences, outcomes, and expectations.

The Role Of Fibrinogen D Domain Intermolecular Association Sites In The Polymerization Of Fibrin And Fibrinogen Tokyo Ii (Γ275 Arg→Cys), Michael W. Mosesson, Kevin R. Siebenlist, James P. Diorio, M. Matsuda, James F. Hainfeld, J. S. Wall

Biomedical Sciences Faculty Research and Publications

Intermolecular end-to-middle domain pairing between a thrombin-exposed 'A' polymerization site in the central 'E' domain of fibrin, and a constitutive complementary 'a' site in each outer 'D' domain ('D:E'), is necessary but not alone sufficient for normal fibrin assembly, as judged from previous studies of a congenital dysfibrinogen, Tokyo II (gamma 275 arg-->cys), which showed defective fibrin clot assembly and a normal D:E interaction (Matsuda, M., M. Baba, K. Morimoto, and C. Nakamikawa, 1983. J. Clin. Invest. 72:1034-1041). In addition to the 'a' polymerization site, two other constitutive intermolecular association sites on fibrinogen D domains have been defined: between …