Medicine and Health Sciences Commons^™

The Second Messenger Camp Elicits Eating By An Anatomically Specific Action In The Perifornical Hypothalamus, Gillard, Arshad Khan, Rickinder Grewal, Bara Mouradi, Stefany Wolfsohn, B. Stanley

Departmental Papers (Biology)

No abstract provided.

Nsu Going Back May Be The Best Way Of Getting Ahead Courses, Seminars, Workshops, Conferences Spring 1998, Nova Southeastern University

Abraham S. Fischler College of Education and School of Criminal Justice College Archive

No abstract provided.

Allopurinol As An Additive To Quinine In The Treatment Of Acute Complicated Falciparum Malaria, P. S. A. Sarma, Anil K. Mandal, Harry Khamis

Population and Public Health Sciences Faculty Publications

The emergence of chloroquine resistance, and a world-wide scarcity of quinine, have resulted in a search for newer antimalarial drugs directed against falciparum malaria. Allopurinol causes virtually complete inhibition of purine biosynthesis of malaria parasites, which may prove lethal to the parasites. This study was designed to examine if allopurinol is additive to quinine in the treatment of acute falciparum malaria. Forty-seven Asian-Indian adults with acute complicated falciparum malaria were assigned to a treatment period of five days. They were randomly assigned to receive either oral allopurinol (12 mg/kg in three divided doses for five days) plus quinine (600 mg …

Ectopic Eruption Of Maxillary First Permanent Molars: Treatment Options And Report Of Two Cases, H. Cem Güngör, Nil Altay

School of Dentistry Faculty Research and Publications

Irreversible ectopic eruption of maxillary first permanent molars may lead to crowded permanent dentition when it is overlooked. The situation usually requires active treatment. In the presented irreversible ectopic eruption cases, distalization and uprighting of maxillary first permanent molars were achieved using removable orthodontic appliances.

Nsu Going Back May Be The Best Way Of Getting Ahead Courses, Seminars, Workshops, Conferences Spring 1998, Nova Southeastern University

Abraham S. Fischler College of Education and School of Criminal Justice College Archive

No abstract provided.

Étude Sur La Sécurité Des Véhicules Tout-Terrain En Opérations Forestières, Serge Massé, Jean-Guy Richard, François Charron, Éric Lemay, Jean-Paul Dionne, Steeve Giguère

Rapports de recherche scientifique

No abstract provided.

Analyse Des Risques Et Étude Des Besoins Relatifs Au Procédé De Meulage Dans L'Industrie Lourde, Cécile Collinge, Éric Lemay, Jean-Luc Wojtowicki, Chantal Tellier, René Benoit, François Charron, François Gauthier, Jean Nicolas, Guy Perrault

Rapports de recherche scientifique

No abstract provided.

Évaluation De La Résistance À La Coupure Des Bottes De Protection Pour Les Travailleurs Forestiers, Denis Turcot, Renaud Daigle

Rapports de recherche scientifique

No abstract provided.

Building Web Sites That Attract Visitors, C. David Shepherd, Daniel Fell

Faculty Articles

The article discusses the use of web sites for health care service marketing. The potential benefits of Internet services for users and care providers are mentioned, but challenges in implementation are also listed. A three generation model of web site design is offered, distinguishing various levels of interactivity, customization, and perceived value. Suggestions are offered applying this model to health care service web sites and their marketing potential.

Basics Of Research (Part 12): Qualitative Research, Cheryl Thompson, B. Lee Walker

Journal Articles: College of Nursing

Although both the assumptions and methods of qualitative and quantitative approaches in nursing research are different, both have the goal of furthering the scientific basis for practice. A variety of qualitative approaches are available, and which approach to use depends on the purpose of the research. In general, qualitative investigations address broad questions related to description, discovery, or theory building, and, as a consequence, the researcher is concerned with the entire context surrounding the phenomenon of interest rather than concentrating on specific variables thought to influence that phenomenon. The type of data collected and the methods of analysis differ, but …

Antigen-Specific Cd8+ T Cells Protect Against Lethal Toxoplasmosis In Mice Infected With Neospora Caninum, Lloyd H. Kasper, Imtiaz A. Khan

Dartmouth Scholarship

Neospora caninum is a coccidial protozoan parasite that appears morphologically indistinguishable from Toxoplasma gondii and that infects a large range of mammals. Both inbred and outbred strains of mice exhibit a high degree of resistance to infection with N. caninum. Three inbred strains of mice (A/J, BALB/c, and C57BL/6) that were infected intraperitoneally with N. caninum were protected against a lethal challenge from T. gondii. Vaccine-induced protection was Neospora dose dependent. A rise in the CD8+ T-cell population in mice that had been vaccinated with N. caninum and challenged with T. gondii was observed. Adoptive transfer of CD8+ T-cell splenocytes …

How Occupational Therapists Teach Older Patients To Use Bathing And Dressing Devices In Rehabilitation., Ruth Levine Schemm, Laura N. Gitlin

Department of Occupational Therapy Faculty Papers

OBJECTIVE: This article describes the methods occupational therapists use to teach bathing and dressing device use to older patients in rehabilitation programs. The relationship of three patient characteristics to five aspects of assistive device instruction was examined.

METHOD: The study sample included 86 patients and 19 occupational therapists who provided the assistive device training. Patients were 55 years of age or older and in rehabilitation for an orthopedic deficit, cerebrovascular accident, or lower limb amputation. Therapists recorded information on teaching methods, perceptions of patient knowledge, and expectations for future device use after each treatment session.

RESULTS: Patients received an average …

Mla's Professional Development Program: How We Took Control Of Our Future, Fred W. Roper

Faculty Publications

No abstract provided.

Investigating Sentinel Events: How To Find And Resolve Root Causes, Larry I. Palmer

Popular Media

No abstract provided.

Haemolytic Uraemic Syndrome In Childhood: An Experience Of 7 Years At The Aga Khan University, S H. Ibrahim, Z A. Bhutta, I A. Khan

Department of Paediatrics and Child Health

We reviewed the case records of all children admitted to the Aga Khan University Hospital (AKUH) with a diagnosis of Haemolytic Uremic Syndrome (HUS) over a 7 year period (July, 1988-June, 1995). A total of 33 patients were admitted to the Pediatric ward at (AKUH) with a median age of 16 months (range 4 months-9 years). 97% cases identified were of the classic variety and no familial case was identified. The mean duration of illness was 27 days, 39% had an illness > 28 days. Diarrhoea and prior antibiotic used was in 97% patients. Oliguria at admission was seen in 52.5% …

Restructuring The Va Health Care System: Safety Net, Training, And Other Considerations, Barbara Skydell

National Health Policy Forum

This paper provides an historical overview of the modern Veterans Administration (VA) healthcare system and describes the multiple missions of the VA — patient care, health professions education, research, and medical preparedness. The VA's reform plan, which addresses issues related to decentralization, management and oversight, resource allocation, eligibility reform, and primary/ambulatory care, is also described and discussed. Challenges facing the VA as it transitions to a greater focus on prevention, primary care, and care management are also addressed.

From Compassion To Compensation: The Effect Of Injury Severity On Mock Jurors’ Liability Judgments, Brian H. Bornstein

Department of Psychology: Faculty Publications

Two studies were performed to ascertain the effect of injury severity on participants’ judgments in a simulated jury task. Participants read a summary of a personal-injury case in which the severity of the plaintiff’s injury was varied: they were asked to judge the defendant’s liability, award compensation, and rate their feelings toward the litigants. In Study 1, more severely hurt plaintiffs were more likely to obtain a favorable verdict, even though evidence of liability was held constant. Greater severity influenced liability judgments only insofar as it elicited positive feelings toward the plaintiff or negative feelings toward the defendant. In Study …

Enhancement Of Atp Levels And Glucose Metabolism During An Infection By Chlamydia: Nmr Studies Of Living Cells, David M. Ojcius, H. Degani, Joel Mispelter, Alice Dautry-Varsat

All Dugoni School of Dentistry Faculty Articles

The Chlamydia species are obligate intracellular bacteria that proliferate only within the infected cell. Since the extracellular bacteria are metabolically inert and there are no cell-free systems for characterizingChlamydia metabolism, we studied metabolic changes related to ATP synthesis and glycolysis in HeLa cells infected withChlamydia psittaci during the course of the 2-day infection cycle using noninvasive 31P and 13C NMR methods. We find that the infection stimulates ATP synthesis in the infected cell, with a peak of ATP levels occurring midway through the infection cycle, when most of the metabolically active bacteria are proliferating. The infection also stimulates synthesis of …

The Federal Employees Health Benefits Program: What Lessons Can It Offer Policymakers?, Karl Polzer

National Health Policy Forum

This paper provides an historical overview of the Federal Employees Health Benefits (FEHB) program and its marketplace dynamics. It also reviews key program features and issues, including payments to health plans, strategies used to mitigate the opportunities for risk selection, and costs.

Predictors Of Children’S Risk Appraisals, David Dilillo, Richard Potts, Susan Himes

Department of Psychology: Faculty Publications

This study explored variables associated with cognitive appraisals of physical risk in a sample of 62 elementary school children. Participants were presented with drawings of persons in three categories of risky situations typical of children, typical of adults, and typical of television plots. They were asked to judge the potential for physical injury in each. Results indicated that children tended to appraise risks in child, adult, and TV-plot risk situations differently, and that each type of situation was predicted by different variables. For the child situations, greater amounts of direct experience with the risk situation itself was found to be …

Interprofessional Working And Continuing Medical Education., Linda Headrick, Peter Wilcock, Paul Batalden

Dartmouth Scholarship

No abstract provided.

Site Visit To Philadelphia — Providing Community-Based Primary Care: Nursing Centers, Chcs, And Other Initiatives, Karen Matherlee

National Health Policy Forum

This site visit provided federal congressional and agency health staff opportunities to visit facilities and engage in discussions on essential community health services. Focused on community-based primary care in a managed care environment, it featured delivery and financing concerns relating to nursing centers, community health centers, public-mission hospitals, and homeless services. In examining the impact of managed care in a rapidly changing health marketplace, it explored the implementation of the Medicaid HealthChoices program in the city as well as access to and delivery of care to persons with neither public nor private insurance. It also looked at the role of …

Differentiating Withdrawal Patterns Between Smokers And Smokeless Tobacco Users, Dennis E. Mcchargue, Frank L. Collins Jr.

Department of Psychology: Faculty Publications

The present study was designed to document smokeless tobacco withdrawal patterns and to examine differential withdrawal responses between smokers and smokeless users. Participants (N = 19) were studied under deprivation and nondeprivation conditions, 1 condition per week. The Withdrawal Symptoms Checklist was administered to assess cognitive and affective changes. Both smokers and smokeless users experienced substantially more withdrawal at 48-hr deprivation compared to the 48-hr nondeprivation condition. Participants in both groups endorsed decreasingly fewer withdrawal symptoms from 0 hr to 48 hr on nondeprivation days. This downward trend suggests a need for stabilizing withdrawal responses before deprivation.

Information Interface - Volume 23, Issue 2 - March/April 1998, George Washington University, Himmelfarb Health Sciences Library

Information Interface (1976 - 2009)

News and information about Himmelfarb Health Sciences Library of interest to users.

Jefferson Alumni Bulletin – Volume Xlvii, Number 2, March 1998

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLVII, Number 2, March 1998

Department Restructurings Respond to the Evolution in Scientific Disciplines, Page 4

The Rb2/p130 Gene and Endometrial Cancer, Page 7

Gene Therapy Trial for Glioblastoma, Page 8

Ovarian Cancer Vaccine is Promising in First Tests, Page 9

Transgenic Mouse for Study of Photoaging, Page 10

Uric Acid Reduces MS Symptoms in Mice, Page 11

Albert Einstein Healthcare Network Will Join Jefferson Health System by July, Page 12

Proposed Amendments to Alumni Association Bylaws, Page 14

Joseph Seltzer, ’71, the Next Alumni President, Page 15

Wallace Miller ’56 Receives RSNA Gold Medal, …

Overexpression Of Glyoxalase-I In Bovine Endothelial Cells Inhibits Intracellular Advanced Glycation Endproduct Formation And Prevents Hyperglycemia-Induced Increases In Macromolecular Endocytosis., Moritsugu Shinohara, P J. Thornalley, Ida Giardino, Paul Beisswenger, Suzanne R. Thorpe, Joelle Onorato, Michael Brownlee

Dartmouth Scholarship

Methylglyoxal (MG), a dicarbonyl compound produced by the fragmentation of triose phosphates, forms advanced glycation endproducts (AGEs) in vitro. Glyoxalase-I catalyzes the conversion of MG to S-D-lactoylglutathione, which in turn is converted to D-lactate by glyoxalase-II. To evaluate directly the effect of glyoxalase-I activity on intracellular AGE formation, GM7373 endothelial cells that stably express human glyoxalase-I were generated. Glyoxalase-I activity in these cells was increased 28-fold compared to neo-transfected control cells (21.80+/-0.1 vs. 0. 76+/-0.02 micromol/min/mg protein, n = 3, P < 0.001). In neo-transfected cells, 30 mM glucose incubation increased MG and D-lactate concentration approximately twofold above 5 MM (35.5+/-5.8 vs. 19.6+/-1.6, P < 0.02, n = 3, and 21.0+/-1.3 vs. 10.0+/-1.2 pmol/ 10(6) cells, n = 3, P < 0.001, respectively). In contrast, in glyoxalase-I-transfected cells, 30 mM glucose incubation did not increase MG concentration at all, while increasing the enzymatic product D-lactate by > 10-fold (18.9+/-3.2 vs. 18.4+/- 5.8, n = 3, P = NS, and 107.1+/-9.0 vs. 9.4+/-0 pmol/10(6) cells, n = …

Research To Practice: The Most Important Member: Facilitating The Focus Person's Participation In Person Centered Planning, Jean Whitney-Thomas, Jaimie Ciulla Timmons

Research to Practice Series, Institute for Community Inclusion

This brief summarizes research that explored the participation of young people in person centered planning, and gives specific recommendations to assist facilitators in maximizing student participation.

Research To Practice: Building Authentic Visions: How To Support The Focus Person In Person Centered Planning, Jean Whitney-Thomas, Jaimie Ciulla Timmons

Research to Practice Series, Institute for Community Inclusion

This brief summarizes research on behavior during a planning session that increased or decreased participation of the focus person. Recommendations challenge team members to think about how their own behavior influences the focus person's participation.

The Role Of Ease Of Retrieval And Attribution In Memory Judgments: Judging Your Memory As Worse Despite Recalling More Events, Piotr Winkielman, Norbert Schwarz, Robert Belli

Department of Psychology: Faculty Publications

Abstract—Participants who had to recall 12 childhood events (a difficult task) were more likely to infer that they could not remember large parts of their childhood than participants who had to recall 4 events (an easy task), although the former recalled three times as many events. This pattern of results suggests that memory judgments are based on the experienced ease or difficulty of recall. Accordingly, the negative impact of recalling 12 events was attenuated when participants were led to attribute the experienced difficulty to the task rather than to the poor quality of their memory. The findings emphasize the role …

Mitochondrial Myopathy With Atypical Subacute Presentation, Oren Cohen, Israel Steiner, Zohar Argov, Avi Ashkenazi, Judith Diment, Ann Saada, Yaron River

Department of Neurology Faculty Papers

Mitochondrial myopathies usually have a chronic course of progressive limb weakness, exercise induced myalgia without muscle tenderness, and normal or only mildly raised serum creatine kinase. Acute or subacute presentation or exacerbation of nervous system signs is common in Leber's hereditary optic neuropathy (LHON) and in mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), but has not been reported for muscle in mitochondrial diseases. We describe a patient who presented with rapidly progressive, subacute muscle weakness due to a mitochondrial disorder.