Medicine and Health Sciences Commons^™

Cardiac Rehabilitation: Gender Differences In Factors Influencing Participation, Lani Lieberman, Marta Meana, Donna E. Stewart

Psychology Faculty Research

This study investigates gender differences in the barriers and incentives that are most influential in the coronary patient's decision to participate in cardiac rehabilitation (CRPs) and suggests strategies to counter these barriers. Patient surveys were administered to consecutive English-speaking attenders and referred nonattenders to a cardiac rehabilitation center at a university healthcare system in Toronto, Canada. A survey questionnaire, constructed from a literature review and advice from key informants, examined potential factors affecting decisions to engage in CRPs. One129 attenders at a CRP and 61 referred nonattenders completed the questionnaire. Physician recommendation was reported to be the most important factor …

Gender-Specific Protection From Microvessel Rarefaction In Female Hypertensive Rats, Paula E. Papanek, Mark J. Rieder, Julian H. Lombard, Andrew S. Greene

Exercise Science Faculty Research and Publications

Epidemiologic studies reveal that women have a significantly lower age-adjusted morbidity and mortality from cardiovascular disease than men, suggesting that gender is a cardiovascular disease risk factor. The mechanism of the “gender protection” is unknown. In this study, we investigated the microvascular remodeling in reduced renal mass plus a high salt (4.0% NaCl) diet model of hypertension (RRM + HS). We hypothesized that women would be protected from the increase in blood pressure and from the microvascular rarefaction associated with RRM + HS hypertension. Studies were designed to determine whether female rats were less susceptible to changes in microvessel density …

Dobutamine Stress Echocardiography For Assessing Coronary Artery Disease After Transplantation In Children., R L. Larsen, P M. Applegate, D A. Dyar, P A. Ribeiro, S D. Fritzsche, N F. Mulla, Girish S. Shirali, M A. Kuhn, R E. Chinnock, P M. Shah

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVES: The purpose of this study was to determine the feasibility, safety and diagnostic accuracy of dobutamine stress echocardiography (DSE) for evaluating posttransplant coronary artery disease (TxCAD) in children, and to determine the frequency of selected cardiac events after normal or abnormal DSE.

BACKGROUND: Posttransplant coronary artery disease is the most common cause of graft loss (late death or retransplantation) after cardiac transplantation (CTx) in children. Coronary angiography, routinely performed to screen for TxCAD, is an invasive procedure with limited sensitivity. The efficacy of DSE for detecting atherosclerotic coronary artery disease is established, but is unknown in children after CTx. …

Expression Of Toxoplasma Gondii-Specific Heat Shock Protein 70 During In Vivo Conversion Of Bradyzoites To Tachyzoites, Neide M. Silva, Ricardo T. Gazzinelli, Deise A. O. Silva, Eloisa A. V. Ferro, Lloyd H. Kasper, Jose R. Mineo

Dartmouth Scholarship

Stage conversion between bradyzoites and tachyzoites was investigated in C57BL/6 mice chronically infected with the ME-49 strain of Toxoplasma gondii. In order to promote bradyzoite-tachyzoite conversion, mice were treated in vivo with neutralizing doses of anti-gamma interferon (IFN-gamma) or anti-tumor necrosis factor alpha (TNF-alpha) antibodies. Expression of parasite-specific antigens SAG-1, SAG-2, and heat shock protein 70 (Hsp-70) was visualized in the central nervous system by immunocytochemistry and measured by photometric assay. The immunosuppressive effect of anti-IFN-gamma or anti-TNF-alpha treatment was immediate, leading to parasite stage conversion as indicated by the increased expression of tachyzoite-specific antigens (SAG-1 and SAG-2) and by …

Cd4(+) T Cells Tolerized Ex Vivo To Host Alloantigen By Anti-Cd40 Ligand (Cd40l:Cd154) Antibody Lose Their Graft-Versus-Host Disease Lethality Capacity But Retain Nominal Antigen Responses., Bruce R. Blazar, Patricia A. Taylor, Randolph J. Noelle, Daniel A. Vallera

Dartmouth Scholarship

A major goal of the transplant field is to tolerize donor T cells to prevent graft-versus-host disease (GVHD) (1). We describe an ex vivo approach in which the blockade of CD40 ligand (CD40L:CD154):CD40 interactions, a pathway required for optimal T cell expansion, induces donor CD4(+) T cells to become tolerant to host alloantigens (2). High doses of tolerized cells did not cause GVHD lethality in vivo. T cells had intact responses to antigens not present during tolerization. Tolerance was long lived and not readily reversible in vivo. These data have significant implications for the use of tolerization approaches to prevent …

Communicating To Beneficiaries About Medicare+Choice: Opportunities And Pitfalls, Nora Super

National Health Policy Forum

This issue brief explores the opportunities and potential pitfalls in communicating to beneficiaries about Medicare+Choice. This issue brief also looks at the difficulties inherent in communicating complex information to a diverse group of older individuals as well as at communications and programmatic challenges related to information overload, marketing concerns, lack of uniform standards, lack of infrastructure, and the vulnerability of various subpopulations.

Synapse, Alabama Health Libraries Association

Synapse - Newsletter of ALHeLa

This is the Summer, 1998 edition of the ALHeLa newsletter - Synapse.

Contents include:

• President's Column
• ALHeLA 1998 Annual Meeting
• NetRx: Internet workshops 3 & 4
• News from Alabama
• National Library of Medicine News
• Alabama Health Libraries Association - 1998 Executive Committee
• Alabama Health Libraries Association - Executive Committee Meeting

2,4-Disulfo Phenyl Butyl Nitrone, Its Salt And Their Use As Pharmaceuticals, John M. Carney

Pharmacology and Nutritional Sciences Faculty Patents

2,4-disulfonyl α-phenyl-tert-butyl nitrone and its pharmaceutically acceptable salts are disclosed. These materials are useful as pharmaceutical agents for oral or parenteral, e.g. intravenous administration to patients suffering from acute central nervous system oxidation as occurs in a stroke or from gradual central nervous system oxidation which can exhibit itself as progressive central nervous system function loss. The materials are also used to ameliorate the side effects of oxidative-damage causing antineoplastic disease treatments.

Medicare Coverage And Technology Diffusion: Past, Present, And Future, Robin J. Strongin

National Health Policy Forum

This issue brief provides an overview of the Medicare coverage process. Coverage involves deciding whether or not to pay for a particular service or product. This brief examines Medicare's coverage determination process, which includes technology assessment, payment determination, and the demand for evidence. Options for improving the coverage determination process are reviewed.

Nornicotine Enantiomers For Use As A Treatment For Dopamine Related Conditions And Disease States, Peter A. Crooks, Linda Phyliss Dwoskin, Michael Thomas Bardo

Pharmaceutical Sciences Faculty Patents

Optically active nornicotine compounds as a treatment for dopamine-related conditions and disease states. Such disease states include the treatment of myasthenia gravis, Parkinson's disease, Alzheimer's disease, schizophrenia, eating disorders, ulcers, drug addiction and as a substitute for psycho-stimulant self-administration.

Cannabinoid Receptor Agonist Efficacy For Stimulating [35S]Gtpγs Binding To Rat Cerebellar Membranes Correlates With Agonist-Induced Decreases In Gdp Affinity, C. S. Breivogel, D. E. Selley, S. R. Childers

Pharmaceutical Sciences

No abstract provided.

Mid-Atlantic Ethics Committee Newsletter, Summer 1998

Mid-Atlantic Ethics Committee Newsletter

No abstract provided.

The Beat Newsletter, College Of Medicine

The Beat Newsletter

This is the July, 1998 edition of the Frederick P. Whiddon College of Medicine's newsletter - The Beat.

Contents include:

• The essential role of Iron
• USA clinical trails goes online
• BENOIT named president-elect of USA chapter of sigma XI
• College of medicine establishes office of health services grants development
• International Efforts
• 'DATELINE' features USA stroke center
• USA comprehensive sickle cell center receives six million dollar grant award
• USA children's research fund
• New Ph.D. graduates in basic medical sciences
• Congratulations...
• American heart association awards research grants
• Honors convocation awards
• The class of 1998 Residency Appointments

Basics Of Research (Part 13): Qualitative Research--An Example, Cheryl Thompson, Edward A. Panacek

Journal Articles: College of Nursing

No abstract provided.

Summer 1998, Southwestern Oklahoma State University

The Sig

The Sig Newsletter from the Southwestern Oklahoma State University College of Pharmacy - Summer 1998

Adolescent Perceptions Of Risk-Taking Behaviors, Susan Matthews

Masters Theses & Specialist Projects

Adolescents often make adult decisions regarding their lifestyle and behavior with little support from their family and community. In this study the researcher examined the difference in risk-taking behaviors between genders and the role that families and communities play in reducing risk-taking behaviors. In the study I further analyzed self-reports of numbers of development assets those students reporting participation in high-risk behaviors. Method: Data were obtained from a sample of convenience of (N=82) 12^th grade students. Behaviors and attitudes were examined using the Search Institute’s Profiles of Student Life survey. Results: Chi square was used to test for significant …

Jefferson Alumni Bulletin – Volume Xlvii, Number 3, July 1998

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XLVII, Number 3, July 1998

Drug Development and Clinical Trials, Page 4

Thomas Jefferson university Hospital is Ranked One of the Top 100 in the Country, Page 8

The W.W. Smith Charitable Trust Gives $1.5 Million, Page 9

First GI Text from an Endoscopic Perspective, Page 9

Brucker Lecture on Refocusing of Managed Care, Page 10

Gene Therapy for Canavan’s Disease, Page 11

Decorin May Be a Natural Cancer Fighter in Cells, Page 13

Clue to How a Protein Works to Suppress Tumors, Page 13

Francis Elected to ACP Board of Regents, Page 23

Appendicitis: A Continuing Challenge, K M. Pal, A Khan

Department of Surgery Docs

Acute appendicitis is a common surgical emergency in urban setting, of a developing country. The computerised hospital patient database at Aga Khan University Hospital, Karachi, was utilised to obtain records of all adults with a histologically proven diagnosis of acute appendicitis. A review of patients treated over a 18 month period was undertaken. One hundred and three appendicectomies were performed for acute appendicitis during this period. The diagnosis was clinical in all cases. Investigations like leucocyte count and lower abdominal ultrasound scan were used to improve diagnostic accuracy without a clear advantage. A number of routine investigations like, haemoglobin estimation …

Nsu Summer Instruction Master's Program In Life Span Care And Administration: “The Profession And Public Policy Family Systems In Substance Abuse Counseling Group Theory And Practice” July – August 1998, Nova Southeastern University

Abraham S. Fischler College of Education and School of Criminal Justice College Archive

No abstract provided.

Étude Sur L'Impact Du Mode De Gestion Des Changements Technologiques Et Organisationnels Sur La Santé Et La Sécurité Du Travail Dans La Fabrication De Produits En Métal Et De Produits Électriques Et Électroniques : Résumé, Camille Legendre, Denis Harrison

Rapports de recherche scientifique

No abstract provided.

Stabilité Des Camions Et Remorques À Bennes Basculantes, Paul-A. Bourassa, Mustapha Khan

Rapports de recherche scientifique

No abstract provided.

L'Incidence De Lombalgies Dans Deux Cohortes : Les Auxiliaires Familiales Et Les Préposées Aux Bénéficiaires Et L'Évaluation Des Conditions De Travail, Dina Hamd, Gilles Thériault

Rapports de recherche scientifique

No abstract provided.

Étude Sur L'Impact Du Mode De Gestion Des Changements Technologiques Et Organisationnels Sur La Santé Et La Sécurité Du Travail Dans La Fabrication De Produits En Métal Et De Produits Électriques Et Électroniques, Camille Legendre, Denis Harrison

Rapports de recherche scientifique

No abstract provided.

L'Utilisation De La Mesure De L'O-Crésol Urinaire Comme Indicateur De L'Exposition Professionnelle Au Toluène : Développement Et Validation D'Un Nouvel Outil, Ginette Truchon, Robert Tradif, Jules Brodeur

Rapports de recherche scientifique

No abstract provided.

Hydatidosis: Experience With Hepatic And Pulmonary Hydatid Disease, T Pishori, R Azami, S M. Ali

Department of Surgery Docs

From 1989-1992, 35 cases comprising of 20 hepatic and 15 pulmonary hydatid cysts were seen. Four patients with pulmonary hydatid disease had previous or concomitant hepatic hydatidosis compared to no concomitant pulmonary hydatid disease in the hepatic group. Hepatic hydatid disease had a greater tendency to be right sides, infected and calcified. Anaphylactic reactions occurred in 3 of 20 patients with hepatic hydatid disease against none in 15 patients with pulmonary disease. Management consisted of evacuation, drainage and obliteration of the residual cavity by capittonage in the lung and omentoplasty in the liver. Two patients, one hepatic and one with …

International Classification For Nursing Practice (Icnp): Most-Frequently Asked Questions, Judith J. Warren, Amy Coenen

College of Nursing Faculty Research and Publications

The International Classification for Nursing Practice (ICNP) is a collaborative project under the auspices of the International Council of Nurses. The alpha version ia available online for comment in preparation for the release of the beta version in 1999. The authors answer the most-frequently asked questions about the ICNP and encourage nurses in the United States to participate in the revision by sending comments and suggestions to the American Nurses Association.

Well Differentiated Hepatocellular Carcinoma Metastasizing To Jaw And Oral Cavity Within Six Months Of Primary Diagnosis., Nazma Afroze, Irshad N. Soomro, Shahid Pervez, Naila Kayani, Sheema H. Hasan

Department of Pathology and Laboratory Medicine

No abstract provided.

Department Of Radiology-Annual Report-July 1, 1997 To June 30, 1998, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Executive Summary Report, July 1, 1997 to June 30, 1998. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 103 pages.

Implantable Controlled Release Device To Deliver Drugs Directly To An Internal Portion Of The Body, Paul Ashton, Paul A. Pearson

Ophthalmology and Visual Science Faculty Patents

A simple and implantable sustained release drug delivery device with an inner core containing an effective amount of a low solubility agent covered by a non-bioerodible polymer coating layer that is permeable to the low solubility agent is disclosed. A method for treating a mammal to obtain a desired local or systemic physiological or pharmacological effect by surgically implanting such a sustained release drug delivery device into a mammal in need of treatment is also disclosed.

Delivery Of An Anti-Hiv-1 Ribozyme Into Hiv-Infected Cells Via Cationic Liposomes, Krystyna Konopka, John J. Rossi, Piotr Swiderski, Vladimir A. Slepushkin, Nejat Düzgüneş

All Dugoni School of Dentistry Faculty Articles

Cationic liposome-mediated intracellular delivery of a fluorescein-labeled chimeric DNA-RNA ribozyme targeted to the HIV-1 5' LTR was investigated, using THP-1, THP-1/HIV-1(IIIB) or HeLa/LAV cells. Different fluorescence patterns were observed when the cells were exposed to Lipofectamine, Lipofectin or DMRIE:DOPE (1:1) complexed to the ribozyme. With Lipofectamine intense cell-associated fluorescence was found. Incubation with Lipofectin resulted in less intense diffuse fluorescence, while with DMRIE an intense but sporadic fluorescence was observed. Differentiated THP-1/HIV-1(IIIB) cells were more susceptible to killing by liposome-ribozyme complexes than THP-1 cells. Under non-cytotoxic conditions (a 4-h treatment) complexes of 5, 10 or 15 μM Lipofectin or DOTAP:DOPE …