Medicine and Health Sciences Commons^™

Effect Of Naringenin Cisplatin Combination On Apoptosis Of Human Tongue Squamous Cell Carcinoma Cell Line, Nahed Atef, Nancy Hussein, Mohamed Grawesh, Mohamed Anees

Mansoura Journal of Dentistry

Aim and Objectives: This research was aimed to evaluate the efficacy of a combination treatment comprising the natural compound Naringenin (NAR) and the chemotherapeutic agent Cisplatin (CP) regarding the reduction of cell viability and the induction of apoptosis in human TSCC (HNO-97) and normal oral epithelial cell (NOEC) lines. Material and Methods: The cytotoxicity and IC50 of NAR, CP, and their combinations were evaluated using the MTT assay. The expression levels of the apoptotic marker genes p53 and caspase-3 were assessed using RT-PCR. Western blot analysis was carried out to assess the protein expression levels of the apoptotic markers Bax …

Evaluation Of Two- Implant Assisted Mandibular Overdentures Of Cobalt Chromium Vs. Peek Combined Denture Bases Regarding Occlusion And Patient Satisfaction: A Within-Subject Study, Khaled M. Diaa, Noha H. El-Shaheed, May A. Hagag, Fatma A. El-Waseef

Mansoura Journal of Dentistry

Objectives The purpose of this within-patient study was to compare two implant-assisted overdentures (IAOs) reinforced either with polyether-ether ketone (PEEK) or cobaltchromium (CO-CR) regarding the percentage of occlusal contact using a digital occlusion analysis system (Occlusense) and to assess patient satisfaction and Oral Health–Related Quality of Life (OHRQoL). Subjects and methods Ten complete edentulous subjects were eligible. All patients were delivered two mandibular implant-assisted overdentures with two reinforcement materials, CO-CR (group I) and PEEK (group II).The mandibular overdentures were retained to the underlying implant fixtures by ball and socket attachments. Patients were evaluated three months after each overdenture use. For …

Swallowing Dynamics Of Two Implants Versus Single Implant-Retained Mandibular Overdentures: Randomized Clinical Trial, Mohamed Taha, Christine Raouf Ibrahim, Abdallah Mohammed Ibrahim

Mansoura Journal of Dentistry

Objective This study evaluated the swallowing dynamics of two-implant (2-IOD) versus singleimplant (1-IOD) mandibular overdentures using the Test of Mastication and Swallowing Solids (TOMASS) and the Timed Water Swallow Test (TWST). Methods Ten completely edentulous patients were selected from the Out-Patient Clinic of the Prosthodontics Department at the Faculty of Dentistry, Mansoura University. All patients initially received conventional complete dentures and were considered Group I, then randomly distributed into two equal groups; Group II (2-IOD) received a twoimplant overdenture with locator attachments, while Group III (1-IOD) received a single implant overdenture with locator attachment. Swallowing dynamics were assessed using the …

Assessment Of Sox2 Expression As A Tumor Stem Cell Marker In Ameloblastoma And Dentigerous Cyst, Haneen Mahmoud Zeen El-Abdeen, Noha Ahmed Mansour, Sherif Yousef Elnagdy, Mohamed Abdel-Monem Tawfik

Mansoura Journal of Dentistry

Objective: The pathogenesis of odontogenic lesions remains unclear; however, a probable explanation could mean the presence of tumor stem cells (TSCs). The preservation of stem cells during early dental development is governed by many transcription factors, including sex-determining region Y (SRY)-box 2 (SOX-2). Numerous studies observed the increased expression of SOX2 in various benign and malignant tumors as its impact on tumorigenesis varies according to tumor type. This research aims to determine the predictive importance of the SOX2 stem cell marker by evaluating its immunoexpression in ameloblastoma (Ab) and dentigerous cyst (DC). Materials and Methods: Twenty-Four samples were part of …

The Prevalence Of Oral Mucosal Thermal And Chemical Burns Following Endodontic Treatments: A Multicenter Study, Mohamed Abd El Rahman El Shreif, Ahmed Adel Abdel-Azim, Noha Nasr El-Zalabany

Mansoura Journal of Dentistry

This multicenter retrospective study investigated the occurrence of oral mucosal thermal and chemical burns during endodontic operations conducted by dental students at Menoufia University (MU), Horus University in Egypt (HUE), and the Modern University for Technology and Information (MTI) over one year. A total of 4,791 clinical records were evaluated. MU identified 42 oral reactive lesions among 1,221 patients (3.4%), including 12 chemical and 30 thermal burns. HUE identified 63 lesions among 1,750 patients (3.6%), comprising 18 chemical and 45 thermal burns. MTI recorded 71 lesions among 1,820 patients (3.9%), including 21 cases of chemical and 50 cases of thermal …

Evaluation Of Retention And Wear Of Nylon Versus Polyether Ketone Ketone (Pekk) Inserts For Locator Attachments Retaining Mandibular Implant Overdenture: A Crossover Study, Mohamed Elghandour, Fatma Fathe Mahanna, Gilan Altonbary

Mansoura Journal of Dentistry

Objective: assessment and comparison between the retention and surface wear of nylon and polyether ketone ketone (PEKK) inserts of locator attachments retaining mandibular implant overdenture. Materials and methods: For this research, six patients, completely edentulous,were selected; each participant had received mandibular implants in the canine regions on each side, followed by locator attachments. Using a crossover design, patients were randomly assigned to receive different mandibular overdentures as follows. 1) Implantretained overdenture with nylon inserts; 2) Implant-retained overdenture with PEKK inserts. Retention measurements were conducted at three-time intervals: T0 (after pickup), T3 (3 months post-insertion of overdenture)and T6 (6 months post-insertion …

Digital Versus Functional Pick-Up Techniques For Two-Implant Retained Mandibular Overdentures: A Crossover Study, Aya E. Elnagar, Khaled M. Zahran, Heba Abo-Elfetouh Elsheikh, Fatma Ahmad El Waseef

Mansoura Journal of Dentistry

Objective: To evaluate two pick-up techniques—digital and functional—for two-implant retained mandibular overdentures with respect to occlusal force distribution using the digital occlusal analysis system (Occlusense®). Patients and Methods: Twenty completely edentulous, healthy patients were selected from the Prosthodontics Department, Faculty of Dentistry, Mansoura University. Conventional complete dentures were first constructed, followed by placement of two implants in the mandibular canine regions using a guided surgical approach and a delayed loading protocol. For each patient, two sets of digitally fabricated mandibular overdentures were constructed. Patients were randomly assigned into two equal groups: Group I received digital complete overdentures with digitally created …

Fracture Resistance Of Monolithic Zirconia Crowns After Endodontically Access Preparation On Premolars Teeth, Abeer Tambah, Nesma Mohamed Magdy El-Gohary, Walid Abd El-Ghafar Al-Zordk

Mansoura Journal of Dentistry

Objective The present study aimed to evaluate the fracture resistance of endodontically treated premolars with monolithic zirconia crowns following standardized endodontic access cavity preparation and restoration with either composite or ceramic inlays. Materials and Methods Twenty extracted human premolars were selected and endodontically treated after creating standardized ovoid access cavities through the zirconia crowns using a highspeed diamond bur under water cooling. Specimens were randomly divided into two groups (n=10 per group): Group 1 restored with bulk-fill composite resin and Group 2 restored with CAD/CAM-fabricated ceramic inlays. Following thermocycling (10,000 cycles, 5–55 °C) and cyclic mechanical loading (240,000 cycles, 50 …

Comparison Of Treatment Outcome Of Occlusal Splints And Physiotherapy Regarding Their Effect On Posture: An In Vivo Pilot Study, Bouchra El Fassih, Amine El Zoghbi, Pascal El Braidy

International Arab Journal of Dentistry

Objectives: The primary objective of the research is to assess occlusal splints and physical exercise effect on posture. The secondary objective is to compare which treatment option has more positive feedback regarding posture adjustment.

Methods: twenty patients with temporomandibular disorders (TMD) were divided into two groups equally, one receiving occlusal splints as a treatment for TMD and the other group receiving physical therapy exercises. They underwent a clinical and postural examination at baseline, after 1 week, after 1 month and after 2 months of treatment. Postural stability was assessed using a force platform (SATEL). Subjects were evaluated in …

Effect Of Adaptation Time On Retention Of Maxillary 3d-Printed Denture Versus Conventional Heat-Cured Acrylic Denture: A Randomized Controlled Trial, Ahmed Hebeshi, Moataz Elmahdy, Sayed Elmasry, Hala Abdelhameed

International Arab Journal of Dentistry

Objectives: The study aimed to investigate the effect of adaptation time on the retention of 3d printed versus conventional heat-cured acrylic maxillary complete dentures.

Methods: 20 patients were distributed into: Group A received ten conventional complete heatcured acrylic dentures and Group B received ten printed complete dentures. Denture retention was measured at 0, 1 , and 3 months.

Results: For acrylic denture and printed denture groups, Mean values in denture retention increased with time but this increase was statistically non-significant. The change in denture retention over time (difference in retention between the third month and at the …

Admitting Science: Problems With Current Admissibility Standards, William O'Donohue, Sneha Gupta

Lewis & Clark Law Review

Attorneys use expert testimony to advance legal positions in courtrooms. Because expert testimony can have tremendous influence over judges and juries, it is admitted only if it meets specific admissibility standards, i.e., Frye and Daubert. These standards provide different admissibility criteria, have been adopted by distinct sets of jurisdictions, and, we argue, are of questionable validity. These standards are attempts to ensure that only knowledge is admissible and are, then, essentially an epistemic matter. Science serves as a proxy for knowledge because science is the epistemic process that has been successful at generating knowledge. However, both epistemology and the philosophy …

Cause Of Death? -- It's Probably Not What's Reported On The Death Certificate, Lauren R. Roth

Lewis & Clark Law Review

In the age of big data, this country has a data problem—inaccurate and incomplete information in death certificates. The problem has long been hidden by the numbers reported—as have the people whose deaths go uncounted, but the COVID-19 pandemic unveiled the scope of the issue. Since the beginning of the pandemic, “excess deaths” (i.e., any deaths above the number predicted by existing mortality models) have increased significantly. Most of these excess deaths are likely attributable to COVID-19 because the decedent was never tested for COVID-19 or it was one of multiple factors contributing to their death. Other deaths are uncounted …

Dentistry And The Law: The Difference Between ‘Non-Covered’ Vs. ‘Disallowed’ Services, Daniel Schulte Jd

The Journal of the Michigan Dental Association

The article clarifies the distinction between "non-covered" and "disallowed" services in dental plan audits. Non-covered services are not included in the patient’s dental plan, often due to plan limitations, while disallowed services are covered but deemed non-payable due to issues like claim deficiencies or lack of documentation. Dentists must review their contracts to understand obligations regarding non-covered services and ensure compliance with HIPAA for patient-paid services. For disallowed services, contesting decisions may be possible depending on the agreement with the dental plan.

The New Professional: Intentional Goal-Setting For 2025, Amrita Patel D.D.S.

The Journal of the Michigan Dental Association

The article emphasizes the importance of intentional goal setting, networking, and leadership for new dentists to achieve long-term success. It advocates for setting clear, measurable goals, breaking them into manageable milestones, and focusing on building strong professional relationships. Networking with mentors and peers, engaging in social media, and participating in dental organizations are highlighted as ways to foster growth and opportunities. Leadership roles, even in small capacities like volunteering or joining committees, are seen as critical steps toward personal development and career advancement. These strategies collectively help new dentists establish a solid foundation for achieving their professional aspirations.

Approaches To Care For Children With Special Needs In Dental Settings: Desensitization And Teledentistry, Hannah Bergeron D.M.D., M.S., Chia-En Tsai D.D.S., Giovana Anovazzi D.D.S., M.Sc., Ph.D., James R. Boynton D.D.S., M.S.

The Journal of the Michigan Dental Association

Children with special health care needs (SHCN) are at a heightened risk of developing chronic physical, developmental, behavioral, or cognitive conditions that significantly affect their oral and general health. These children often encounter significant barriers to receiving adequate dental care, which contributes to neglected oral health needs. Common challenges include increased risk of dental diseases due to medication use, oral hygiene difficulties, and dietary restrictions. Newer strategies aimed at overcoming these barriers include the use of dental social stories, desensitization techniques, and teledentistry.

Social stories offer a structured way for parents to help prepare children for their dental visits. Desensitization …

J Mich Dent Assoc January 2025

The Journal of the Michigan Dental Association

Each month, the Journal of the Michigan Dental Association provides news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. It is the primary publication reaching Michigan dentists. The January issue sets the tone for February, the observance of Children’s Dental Health Month.

Michigan Academy of Pediatric Dentistry President Jessica Bentoski welcomes readers to this special issue, which features a cover feature on “Approaches to Care for Children with Special Needs in Dental Settings: Desensitization and Teledentistry” and a supporting article on “General Dentists’ Education, Knowledge, Attitudes, and Behavior Concerning the Effects …

Marketing The Message: Maximizing Engagement With Digital Publications Through Social Media, Email, And Analytics, Rich Evans

AADEJ - The Communicator

This article outlines a strategic approach for professional associations to enhance engagement with their digital publications in today's digital-first environment. Drawing from the Michigan Dental Association (MDA)'s transition to a fully digital Journal, it emphasizes the vital role of marketing and analytics. Key recommendations include leveraging social media for strategic visibility (e.g., summarizing articles, tagging authors, video pitches), implementing direct email delivery to members (e.g., monthly digests, audience segmentation), and ensuring easy website integration for accessible content. The piece also stresses the importance of mobile-responsive design, clear formatting, and multimedia embedding to improve the digital reading experience. It suggests evaluating …

Coaching Authors With Generative Ai, Christopher J. Smiley

AADEJ - The Communicator

This paper outlines a systematic methodology for dental editors to coach authors in the ethical use of generative artificial intelligence (GAI). By adopting "AI-First" or "Write-First" strategies, editors can help authors refine their thesis statements and improve logical flow while maintaining human oversight and intellectual integrity. Dr. Smiley asserts that GAI should be used as a tool to enhance communication rather than replace human creativity, ensuring authors remain accountable for their final expressions.

Who Calls For Urgent Action To Ban Flavoured Tobacco And Nicotine Products

Neurosciences

No abstract provided.

“Knowledge And Attitude Towards Ect Among The Caregivers Of Patients In A Tertiary Mental Health Care Setting”., Kajusree Borah, Arunjyoti Baruah Dr, Sandeep Kollipara

Manipal Journal of Nursing and Health Sciences

Background: Caregivers play an important role in shaping patients’ experiences with ECT. Despite evidence that ECT is an effective and safe treatment, certain factors, such as social stigma, inadequate knowledge, doubt about efficacy, and safety, have limited its use. With adequate knowledge, information, and understanding caregiver, as well as the patient, will develop a positive attitude towards it simultaneously. Aim: To assess the correlation of knowledge and attitude towards ECT among the caregivers of patients in a tertiary mental health care setting. Methodology: This study employed a descriptive correlational research design, conducted within a tertiary mental health care setting. …

Perceived Obligations Of Older Partners In Living-Apart-Together Relationships, Allison M. Martin, Timothy S. Killian

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Older and middle-aged adults are increasingly in Living-Apart-Together (LAT) relationships characterized by committed romantic relationships without marriage and cohabitation. Because of assumptions that older adults will receive family caregiving as they grow older and need caregiving, it is not clear how people are likely to perceive obligations to provide caregiving assistance. As adults move into old age and incidence rates of Alzheimer’s Disease or Related Dementia (ADRD) increase, questions about the availability of family members to provide needed assistance are complicated by LAT relationships. The purpose of this study was to examine perceived obligations to provide assistance to older adults …

The Ethical Imperative Of Leadership In Dentistry, Mike Graham, Toni M. Roucka Rn, Dds, Ma, Facd

Journal of the American College of Dentists

Leadership is one of the four pillars of the American College of Dentists, taking its place alongside excellence, ethics, and professionalism. Leadership in dentistry carries an inherent ethical responsibility to uphold the trust and well-being of those who depend on us—our patients, our teams, and the community. When leaders in our field exercise their influence, they wield significant power over patient outcomes, industry standards, and public health policy. With this influence comes an imperative to act ethically, to ensure that decisions are guided by a commitment to care, integrity, and the best interests of those we serve. At the heart …

Interprofessional Models Of Care: A Strategic Framework For Advancing Integrated Healthcare, Daniel J. Pihlstrom Dds

Journal of the American College of Dentists

Interprofessional models of care (IPMC) provide a vital framework for improving the delivery of health services through the alignment of medical and dental protocols, integration of shared health data, and collaborative, team-based care. Drawing on both empirical data and theoretical models, this analysis explores how integrated care can become the norm rather than the exception.

Unifying Health And Oral Health—An Ethical Imperative, Shelia Brear Bds

Journal of the American College of Dentists

The 2024 Ethics Summit, Breaking Down the Silos, convened by the American College of Dentists, marked a pivotal moment in the ongoing discourse on the ethical responsibilities of oral healthcare professionals. This distinguished gathering of interprofessional experts offered an insightful and urgent exploration into one of healthcare’s most pressing yet underexamined ethical imperatives: the moral obligation to fully integrate oral health into the broader healthcare system. The summit’s focus aligns powerfully with the mission of the American College of Dentists to advance excellence, ethics, professionalism, and leadership in oral healthcare.

Analisis Situasi Masalah Penyakit Infeksi Menular Seksual Di Kota Bogor Tahun 2024, Wardiman Wardiman, Ratna Djuwita, Bai Kusnadi

Jurnal Epidemiologi Kesehatan Indonesia

Abstrak

Infeksi menular seksual (IMS) masih menjadi tantangan kesehatan global, termasuk di Indonesia, terutama pada kelompok usia produktif 15-49 tahun. Di Kota Bogor, angka kasus IMS mengalami peningkatan, namum belum sepenuhnya menggambarkan kondisi yang sebenarnya. Penelitian ini bertujuan untuk menganalisis situasi IMS secara mendalam dan menetapkan prioritas masalah kesehatan menggunakan metode PAHO-adapted Hanlon, yang mengacu pada pembobotan Basic Priority Rating (BPR) berdasarkan lima kriteria utama, yaitu, A=Masalah utama; B=Keseriusan masalah; C=Efektivitas intervensi; E=Ketidakadilan; F=Kapasitas institusi dalam mengatasi masalah. Penelitian ini dilaksanakan di Dinas kesehatan Kota Bogor pada Oktober 2024 hingga Januari 2025, dengan pendekatan kualitatif dan kuantitatif, serta disajikan secara …

Gambaran Putus Obat Berdasarkan Sosial-Demografi Pada Penderita Tuberkulosis Di Indonesia Tahun 2023: Cross-Sectional Study, Anindya Oktaria Yudhanti, Arina Syahida Hurva Radisan Saf, Benita Riska, Enita Fransiska Tamba

Jurnal Epidemiologi Kesehatan Indonesia

Introduction: Tuberculosis is an infectious disease that spreads through the air. Based on data at the international and national levels, there has been an increase. Most pulmonary TB patients are cured with consecutive antibiotic treatment for 6-9 months, but there are still patients who eventually drop out of treatment. This could be a challenge in achieving the international tuberculosis elimination target of 2035 and the national target of 2030. Methods: This study analyzed the socio-demographic distribution and dropout analysis of Tuberculosis patients in Indonesia in 2023 based on SKI data with a cross-sectional study type. Results: The incidence of drug …

Gambaran Kasus Gondongan Pada Sekolah Dasar Negeri 010 Makroman, Samarinda, Dwi Listiani, Ashri Budi Astuti, Jami'an Jami'an, Eko Prasetya Budi, Arif Sumarianto, Irfansyah Baharuddin Pakki

Jurnal Epidemiologi Kesehatan Indonesia

Mumps is an infectious disease caused by a viral infection, often attacking the salivary glands, especially the parotid glands. This disease is self-limiting and common in elementary school children. This study aims to describe the prevalence, symptoms, and impact of mumps in students of SD Negeri 010 Makroman, Samarinda, as well as evaluate risk factors and relevant prevention efforts. With a descriptive research design, data was obtained from a population of 307 students through secondary data from the Makroman Health Center and direct on-site investigations. An attack rate of 3.58% indicates a limited impact on at-risk populations, but it is …

Mercury Concentrations, Health, And Marine Food Consumption Across Four Eastern Caribbean Populations: Insights From A Novel Community-Based Study, Russell Fielding, Catherine Brown, Jessica Dutton, Martin S. Forde, Heather Harewood, Lisa Hunt, Catherine Macdonald, Cameron Mewhirter, Vincent Reid, Madison Smith, Holly Taylor, Katelyn Zimmerman

Gulf and Caribbean Research

Mercury (Hg), as an environmental pollutant, can have harmful effects on human health. A common way that people are exposed to Hg is through seafood consumption. This project was designed to investigate Hg exposure through seafood consumption and its health effects among adults in 4 Caribbean countries: Barbados (n = 117), Grenada (n = 90), St. Lucia (n = 126), and St. Vincent & the Grenadines (n = 77). We applied a novel, community—based method, which involved recruiting and paying local barbers and hairstylists to collect hair samples from their clients who consented to join the project as participants. Participants …

Heartbeats, Romy Pein

Quill & Scope

No abstract provided.

Desert Tv At Cafecito, Ivan Dominguez

Quill & Scope

Arizona, 2024