Alterations Of Tnf-Α And Il-8 Levels In Gingival Crevicular Fluid Among Different Types Of Smoking Following Phase I Periodontal Therapy In Periodontitis Patients, Nouran Abdelmaged Dr., Nivine Ibrahim Ragy Professor, Zienab Farid Dr.

Future Dental Journal

Aim: The purpose of the current research was to evaluate the impacts of different smoking types on GCF levels of TNF-α & IL-8 after phase I periodontal therapy. The study compared between traditional cigarettes and heated tobacco products (HTPs) in contrast to non-smokers following non-surgical treatment of moderate periodontitis patients. Subjects & methods: Forty-five patients with moderate generalized chronic periodontitis had been enrolled in this research. They had been divided into 3 equal groups and received non-surgical periodontal treatment. Samples of gingival crevicular fluid had been collected from periodontal pockets at baseline & after six months. The collected …

Antibacterial Effect Of Silver Diamine Fluoride And Glass Ionomer Cement Restorations Against Streptococcus Mutans (An In Vitro Study), Shima Mahmoud Ibrahim Dr., Osama Ibrahim Elshahawy Prof Dr., Sara Ahmed Mahmoud Prof Dr., Eman Alaa Eldeen Abd Allah Associate Professor

Future Dental Journal

Objective: To determine the antibacterial effect of silver diamine fluoride and glass ionomer cement restoration against streptococcus mutans. Materials and methods: This study included 10 blood agar plates, the anti-bacterial efficacy of each matter was estimated against streptococcus mutans using agar diffusion test. Streptococcus mutans was prepared on blood gar plate. Three wells (A,B,C) with a diameter of 5 mm were performed in each plate and totally filled with one of the tested substances. The test materials were divided into three groups: group A (SDF): silver diamine fluoride, group B (GI): glass ionomer and group C (SDF+GI) were placed into …

Assessment Of Dental Anxiety And Fear In A Group Of Children And Adolescents With Molar Incisor Hypomineralisation (Mih), A Comparative Cross Sectional Study, Jumana Adel Alshafei, Osama Ibrahim El-Shahawy, Randa Youssef, Eman Alaa

Future Dental Journal

Introduction: patients with Molar Incisor Hypomineralisation are highly susceptible to caries and hypersensitivity because of the altered morphology and structure of the enamel prisms, which can result in complication in management during the treatment.

Aim: the aim of the study was to assess the Dental Fear and Anxiety in a group of Egyptian children and adolescents with MIH.

Subjects and methods: the study was a comparative cross-sectional study included 200 Egyptian children and adolescents aged from 6 to 17 years old ,100 patients diagnosed with MIH and 100 as a control group attending the Pediatric Dentistry and Dental Public Health …

Oral Health-Related Quality Of Life: A Cross-Sectional Comparison Between Dental And Non-Dental Students At Newgiza University, Fayrouz Sayed Saber, Mohamed Sabry, Alaa Nawar, Mayar El Weik

Future Dental Journal

Introduction: Evaluating oral health-related quality of life (OHRQoL) among Egyptian dental students can broaden the traditional focus on dental criteria to include social, emotional, and functional aspects. This perspective shift is vital as background knowledge influences both perceptions and behaviors regarding oral health. Comparing OHRQoL between dental and non-dental students is crucial for understanding these differences.

Aim: This study aims to compare the oral health related quality of life and oral hygiene measures between a group of dental and non-dental students at Newgiza University.

Methods: During the Oral Health Day at Newgiza University, the short form of the Oral …

Accuracy Of Dolphin Imaging Software Vs Quickceph Studio In Prediction Of The Extraction Treatment Outcomes Of Class Ii Malocclusion In Adult Patients: A Retrospective Study, Mostafa Ahmad Hashem, Hala Munir Abdel Majeed, Sameh Mohamed Talaat

Future Dental Journal

This study aimed to evaluate the accuracy of Dolphin Imaging Software and QuickCeph Studio in predicting the soft tissue profile following extraction treatment of Class II malocclusion. The study included 32 Class II patients aged 14 to 30 years who had previously undergone orthodontic treatment with extraction of first premolars. The accuracy of both software applications was evaluated using preoperative and postoperative lateral cephalometric X-rays and extra-oral photographs to compare the predicted outcomes with the actual post-treatment outcomes. Results: there was no significant difference between posttreatment and predicted regarding dolphin software while there was only a significant difference between posttreatment …

Scanning Electron Microscope Evaluation Of Enamel Damage After Bracket Debonding Using Two Techniques For Residual Resin Removal: (A Randomized Clinical Trial), Besher Maher Hawout Besher, Essam Nassef Prof. Dr., Hala Munir Prof. Dr., Faten Eid Prof. Dr.

Future Dental Journal

Introduction: The purpose of this study was evaluation of enamel damage index (EDI) immediately after adhesive removal and after exposure to intraoral fluids for a period of 3 months, using tungsten carbide burs compared to stainbuster burs.

Methods: Twenty patients were randomly assigned into 2 main groups 10 patients each, where in Group I the enamel damage index was evaluated immediately after adhesive removal and in Group II the enamel damage index was evaluated after 3 months follow up. Forty premolars in each group were randomly assigned to either TC bur or SB bur groups. In Group 2, replicas using …

P53 Tumor Suppressor Gene Expression In Ameloblastoma Subtypes: An Immunohistochemical Analysis, Yara Y. Mouselhy, Ahmed Abozekry, Iman M. Abdel Meguid, Raneem F. Obeid, Mai Abdelhalim Hamouda, Hala El-Kammar

Future Dental Journal

Background: Ameloblastoma is the most frequent of the benign epithelial odontogenic tumours. It exhibits a unique biologic behavior which demands meticulous understanding for thorough diagnosis and management. P53 tumor suppressor protein functions as a gatekeeper of cell division, inducing either cell cycle arrest or apoptosis. While mutations in the p53 gene are often detected in human cancers; the role of p53 in ameloblastoma remains elusive.

Material and methods: To investigate p53 expression in ameloblastoma, a retrospective study was designed to evaluate and compare immunohistochemical p53 protein expression patterns, in follicular ameloblastoma, plexiform ameloblastoma and unicystic ameloblastoma. Nine paraffin-embedded archival tissue …

Postoperative Pain After Different Root Canal Irrigant Activation Methods In Patients With Non-Vital Teeth (Randomized Clinical Trial), Passant Tarek El Zainy, Wael Ahmed Hessein Prof, Mahmoud Mohamed Badr

Future Dental Journal

Objective To evaluate the effect of ultrasonic irrigation or manual dynamic agitation on postoperative pain in patients with necrotic teeth with symptomatic apical periodontitis using (VAS) scale.

Methods Seventy-eight patients diagnosed with necrotic mandibular first molar with symptomatic apical periodontitis were randomly allocated into 1 of 3 separate groups (n=26); Manual Dynamic Agitation group, Ultra X group, or Navitip group (control). After a single visit root canal treatment and a specific method of agitation, depending on each group, the patients were given a questionnaire on which the patient would mark the degree of pain in a scale from 0 to …

The Effect Of Nanoparticles Incorporation On Antimicrobial And Bond Strength Properties Of Bio-Ceramic Sealer (An In Vitro Study), Hatem Tarek Dr., Wael Hussein Kamel Prof., Nehal Ezzat Sabet Prof., Adel Abdelwahed Associate Prof.

Future Dental Journal

Aim: This research intended to assess how the addition of nanoparticles impacts the antimicrobial effectiveness and bonding ability of bio-ceramic sealers when compared to resin-based sealers.. Materials and Methods: Bioactive glass nanoparticles (BG NPs) were prepared via a modified Stöber process. AH Plus and Bio-C Sealer were mixed with (BG NPs). Part I: Antibacterial tests involved 96 tubes divided into 6 main groups , tests were conducted using Enterococcus faecalis using direct contact test (DCT). Part II: Push-out tests utilized 32 extracted human permanent anterior teeth and were performed to evaluate bond strength. Results: Resin-based sealers and bio-ceramic sealers exhibited …

Assessing The Usefulness Of Solid-Phase Microextraction (Spme) For Methadone And Its Metabolites Analysis In Urine Samples Using Hplc/Spme Fibre Tips, Majidah Mahmoud Alfahmi

Saudi Toxicology Journal

Solid-phase microextraction (SPME) has been introduced as a novel, simple and single- step technique of extracting methadone (MDN), 2-ethylidene-1,5-dimethyl-3,3- diphenylpyrrolidine (EDDP) and 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (EMDP) from urine samples. In this study, direct immersion SPME followed by high-performance liquid chromatography with ultraviolet detection (HPLC-UV) was developed to identify methadone and its metabolites. The separation was performed on a Gemini C18 (octadecyl carbon chain) analytical column (150 x 2.0 mm, 5 µm) and detected by an ultraviolet (UV) detector at 210 nm. The factors influencing the SPME procedure, such as the sample’s pH, fibre coating type, salt addition and desorption solvent type were …

Artificial Intelligence (Ai) In Pharmacy, Giang Nguyen, Elizabeth Sartschev, John Reyes, Allie Honigford, Marisa Petrunich, Kiley Devoll, Brianna Lu, Joshua Honaker, T'Bony M. Jewell

Pharmacy and Wellness Review

Artificial Intelligence (AI) has transformed the pharmaceutical field by enabling computer software systems to learn and perform human behavior. Specifically, AI has revolutionized chronic diabetes management through continuous glucose monitoring, showcasing its immense potential in healthcare. However, alongside its transformative impact, AI’s increasing role in healthcare has prompted concerns over privacy and its premature integration. Despite these challenges, AI offers limitless opportunities to improve medication management and treatment regimens, driving advancements across various domains. From improving CT imaging to enhancing adenoma detection in colonoscopies and facilitating medication adherence, AI’s impact on healthcare is profound. Furthermore, AI plays a pivotal role …

Effect Of Vitamin K Supplementation On Insulin Resistance: A Review, Samantha Mccord, Rebecca Willier, Kaitlyn Kirby, Kaylin Mahoney, Lance Dillon, Rileigh Rahrig, Brianna Lu, Joshua Honaker, Emily Eddy

Pharmacy and Wellness Review

Insulin resistance is one of the pathological hallmarks that leads to the development of type II diabetes mellitus (T2DM). Around 40% of people aged 18 to 44 living in the United States have insulin resistance. Recent research, coupled with a better understanding of how vitamin K functions in the body, suggests that this vitamin could potentially help reduce insulin resistance. Vitamin K is not included in the American Diabetes Association (ADA) guidelines for the treatment of insulin resistance, but it has been shown to have some benefits in patients with T2DM. It may also serve as a treatment option for …

The Application And Innovation Of Casgevy On Sickle Cell Disease, Emily Tackett, Le Thien Truc Pham, Hannah Salamie, Arin Wade, Allison Provenzale, Alexander Defranco, Ashley Jacob, Brianna Lu, Joshua Honaker, Amy Stockert

Pharmacy and Wellness Review

Casgevy, sickle cell anemia, SCA, sickle cell disease, SCD, CRISPR/Cas9, hydroxyurea, hemoglobin, Hb, l-glutamine, voxelotor, Crizanlizumab, Lyfgenia, stem cells, genetics, pharmacogenetics, pharmacogenomics

Poor Birth Outcomes Related To Cannabis Use In Pregnancy, Reese Weissenfluh, Madison Hall, Branden Kadlubowski, Makayla Eversole, Elizabeth Clary, Layla Dials, Brenna Hissong, Brianna Lu, Joshua Honaker, Manoranjan D'Souza

Pharmacy and Wellness Review

Pregnancy, a period of dynamic physiological changes, necessitates careful consideration of external influences on maternal and fetal health. Despite increasing legalization and prevalence, the impact of cannabis use during gestation remains a topic of significant concern and investigation.

Recent studies have shed light on the consequences of in utero cannabis exposure, encompassing both fetal and maternal outcomes. Notably, several studies have identified associations between cannabis exposure during pregnancy and adverse fetal outcomes, including small-for-gestational-age birth, altered neurodevelopment, preterm birth, and increased risk of neonatal morbidity. Evidence to date underscores the urgent need for education, intervention, and regulatory oversight regarding cannabis …

Effectiveness Of Empagliflozin In Treating Patients With Heart Failure With Preserved Ejection Fraction: A Systematic Review, Sara Abou Al-Saud

Journal of the Saudi Heart Association

Aim

The goal of this systematic review is to determine the effectiveness of empagliflozin in managing patients with heart failure with preserved ejection fraction (HFpEF) as compared with a placebo

Methods

Web of Science, Cochrane, PubMed, and Scopus databases were searched for articles from 2000 to 2023. Reference lists of articles were manually screened. Trials that recruited patients with HFpEF and reported the effects of empagliflozin were included. Endnote X9 software was used for the study screening process.

Results

1029 non-duplicate articles were identified from the literature and 9 were selected for inclusion in this review. The included papers were …

Wellness Literature Review - 2024, Bidhu Sharma, Martin Huecker, Brian A. Ferguson

Journal of Wellness

Introduction: The Journal of Wellness has moved to a single calendar year editorial review of wellness literature. This annual review includes studies published in 2024.

Methods: Authors conducted a PubMed and Google Scholar keyword search, narrowing results to interventional studies / clinical trials in humans.

Literature in Review: We conducted a thematic review of a selection of relevant papers from the literature search. COVID-19 crisis has exacerbated the rate of burnout and impacted well-being of healthcare providers. Need for intervention in this area has arisen significantly since the pandemic. Post pandemic, working conditions have been normalized to some extent, however, …

Subtalar Dislocation With Isolated Talonavicular Dislocation – A Unique Case, Yaser J. Rahim, Naveen J. Pattisapu, Maxwell C. Alley

The Lahey Journal

Subtalar joint dislocations are infrequent injuries of the foot involving interruption of the articulations in the subtalar joint complex. These injuries involve dislocation of the talocalcaneal and talonavicular joints simultaneously with or without associated fractures. Subtalar joint dislocations are classified as medial or lateral, with medial dislocations occurring more commonly. Medial subtalar dislocations are generally not associated with other injuries whereas lateral subtalar dislocations are more frequently accompanied by fractures of talus, calcaneus or navicular. Prompt recognition of this dislocation and other injuries prevent negative sequelae associated with delayed treatment, and patients typically have a good outcome and return to …

Antidiabetic Properties Of Prickly Pear (Opuntia Ficus-Indica) Fruit Extract, Kenzy Aidan Joseph Mckay

The Undergraduate Research Journal

Diabetes mellitus is a metabolic disorder that claims 1.5 million lives annually. Opuntia ficus-indica, commonly known as the prickly pear, has been commonly used in traditional folk medicine for its hypoglycemic properties. It has been claimed that it has antimicrobial and antioxidant properties as well. The plant is native to Mexico and is commonly found in the middle east and India and folk medicine from all of these areas have been using prickly pear medicinally for years. To test these claims an extract of locally sourced Opuntia ficus-indica was prepared using the flesh and seeds of the fruit. The …

Priming For Practice: A Teaching Strategy, Jennifer Tomesko, Diane L. Rigassio Radler

Journal of Dietetic Education

Authors present a brief educational teaching strategy.

Use Of Simulation In Dietetic Internships: A Qualitative Exploration Of Program Director Attitudes And Motivations, Theresa B. O'Reilly, Amy J. Nwora, Megan Whelan, Mary-Pat Maciolek

Journal of Dietetic Education

The use of simulation holds promise for the future of dietetics education for its use as an alternative for up to 30% of the 1,000 supervised practice hours for the training of Registered Dietitian Nutritionists. Even more so, simulation is a teaching tool. When done well, simulation can challenge students in a safe environment where they can receive constructive feedback from expert guides and meaningfully reflect on their learning. The purpose of this study was to interview dietetic internship (DI) program directors on their attitudes and motivations on the use of simulation in their programs, targeting the heavily program-congested states …

Conceptual Diagrams Help Dietetic Students To Understand And Apply The Nutrition Care Process, Janica Jamieson, Bojana Kovacic, Philippa Lyons-Wall, Therese O'Sullivan

Journal of Dietetic Education

Aim: To evaluate the impact of a conceptual diagram assessment task on dietetic student knowledge of and confidence applying the Nutrition Care Process. Methods: Situated within a pragmatic research paradigm, this mixed methods study applied a survey administered before and after a conceptual diagram assessment task using the Nutrition Care Process to explore changes in student knowledge, self-reported confidence, perceptions towards the Nutrition Care Process, and student experience. Nineteen students enrolled in a first-semester unit within a Master level dietetic course completed the assessment task, which visually presented a client case sourced from the student-run clinic within the Nutrition Care …

Cover, Editor's Message, Table Of Contents, Diana Cuy Castellanos

Journal of Dietetic Education

No abstract provided.

The Usefulness Of 3d Heart Models As A Tool Of Congenital Heart Disease Education: A Narrative Review, Raghad Abdulaziz Alhojailan, Reghd Husain M Alkhalifah, Bana Albani, Majed Wadi

Journal of the Saudi Heart Association

Objectives: The objective of this review is to evaluate the effectiveness of three-dimensional (3D) heart models as teaching tools for congenital heart disease (CHD), addressing the limitations of traditional medical education methods. Methods: A thorough literature review was conducted using PubMed, Google Scholar, Scientific Direct and Scopus databases. Relevant articles were screened and selected based on their discussion of the application of 3D models in CHD education. Results: The comprehensive review of 19 studies revealed that 3D heart models provide students, healthcare professionals, and patients with meaningful experiences that significantly enhance understanding and learning outcomes. These models improve …

Advances In 2024: Update And Thanking Our Peer Reviewers, Richard Alweis, Christina Goodermote, Elizabeth Mamo

Advances in Clinical Medical Research and Healthcare Delivery

The Editors review the performance of the journal and thank the peer reviewers for 2024.

Monroe County Medical Society Abstract Competition, Janine Fogarty

Advances in Clinical Medical Research and Healthcare Delivery

Established in 1821 in Rochester, New York, Monroe County Medical Society is a non-profit, professional organization whose 1,200 members are physicians, residents, and medical students. The society advocates for physicians and patients for the betterment of the medical profession and the health of the community. Monroe County Medical Society encompasses the 7th District Branch of the Medical Society of the State of New York and serves the New York State counties of Monroe, Livingston, Ontario, Seneca, Steuben, Wayne & Yates Counties

A call for abstracts was requested for the Monroe County Medical Society 203rd Anniversary Gala held on September 25th, …

Murder Mystery Solved! Unmasking Multi-Generational Familial Death As A Result Of Brugada Syndrome, Ryan Tam, Sandres Aodish, Jeremiah Tom, Mohammad Jawish

Advances in Clinical Medical Research and Healthcare Delivery

Brugada syndrome is an inherited condition that has an increased risk of developing ventricular arrhythmias and sudden cardiac death. This condition can be diagnosed by using the Shanghai Scoring System. Here, we present a patient with an incidental finding of Type 1 Brugada pattern on electrocardiogram amidst atypical neurological findings on presentation to the emergency department and a history of cardiac-related familial deaths of uncertain etiology.

One Center's Experience Of Pulmonary Embolism After Covid-19: Impact Of Vaccination Status, Cara Gose, Kaylee Dixon, Andrea M. Bodine Md

Advances in Clinical Medical Research and Healthcare Delivery

Background: The incidence of pulmonary embolism (PE) has increased since the outbreak of the COVID-19 pandemic and may be due to the observed hypercoagulable state. There is conflicting evidence that thromboembolism risk increases after vaccination and that vaccines decrease the probability of having a thromboembolic event. This study aimed to explore how vaccination status impacts occurrence of PE after a positive COVID-19 test. The hypothesis was that vaccinated, immunocompetent patients have a lower incidence of PE after COVID-19 compared to unvaccinated patients.

Methods: This was a retrospective chart review at a teaching hospital in New England from 1/01/2021 to 3/31/2023 …

A Compelling Case Of The Use Of Electroconvulsive Therapy In Severe Treatment Resistant Depression With Suicidality, Neha Narayanan, Ryan Tam, James Mead

Advances in Clinical Medical Research and Healthcare Delivery

Treatment-resistant depression is a condition that occurs when an individual, experiencing major depressive disorder episodes, has failed the first line of treatment with medication therapy of adequate dose and duration. This is important to be addressed as there is a high likelihood of progression to having thoughts and an intended plan for suicide. Electroconvulsive therapy is a recommended option for those who have failed medication therapy, but it has been controversial in its use due to its stigma and side effects of memory impairment. Here, we present a case of a patient who had undergone several sessions of ECT with …

Special Patient Populations - A Case Report Of A Jehovah’S Witness, Michael P. Mullinax, S. Jiaming Lin, Paige M. Kieper, Jake W. Vogel, Orlando Nunez Isaac

Advances in Clinical Medical Research and Healthcare Delivery

This case report describes a Jehovah’s Witness patient with a life-threatening exacerbation of chronic anemia, warranting blood transfusion. This case highlights the complex medical management and ethical considerations encountered when treating special patient populations. Moreover, this case illustrates the delicate balance that healthcare providers must maintain when delivering necessary medical interventions to patients with competing religious beliefs.

Enfortumab Vedotin Induced Cutaneous Manifestations, Zeni Kharel, Farhan S. Imran

Advances in Clinical Medical Research and Healthcare Delivery

Enfortumab vedotin(EV) comprises of an anti–nectin-4 monoclonal antibody bound to the chemotherapeutic agent called monomethyl auristatin E, forming an antibody-drug conjugate. It is currently approved for the treatment of locally advanced or metastatic urothelial carcinoma after disease progression on two prior lines of therapy including chemotherapy and immunotherapy. Since nectin-4 is also expressed on the surface of keratinocytes, cutaneous adverse effects are common. Our clinical image depicts a cutaneous adverse reaction to EV and its resolution after discontinuation of EV.