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Articles 60661 - 60690 of 62491

Full-Text Articles in Medicine and Health Sciences

"Slow" And "Fast" Muscle Fibers, Ernest Gutmann Jan 1966

"Slow" And "Fast" Muscle Fibers, Ernest Gutmann

MCV/Q, Medical College of Virginia Quarterly

On the basis of the clear-cut differentiation used in fast (twitch) and slow (tonic) muscles of the frog, both the fast E.D.L. and the slow soleus muscle should be considered twitch muscles. However, they reveal a marked differential behavior in their contracture responses to ACh and caffeine. Moreover, all the slow muscles I have studied (i.e.. the L.D.A. of the chicken, the rectus abdominis of the frog, and the soleus of the rat) show a higher rate of proteosynthesis. This may be related to the basic function of slow muscles concerned with long-lasting maintenance of tension, the extreme being, for …

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Contents Jan 1966

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, Spring 1966, Volume Two, Number One.

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Plasma Volume Expansion And Proximal Tubular Reabsorption Of Salt And Water By Rat Kidney, Sidney Solomon, Harald Sonnenberg Jan 1966

Plasma Volume Expansion And Proximal Tubular Reabsorption Of Salt And Water By Rat Kidney, Sidney Solomon, Harald Sonnenberg

MCV/Q, Medical College of Virginia Quarterly

Venous infusion of both hypertonic and isotonic solutions has been known to lead to diuresis and natriuresis. In recent micropuncture studies, attempts have been made to identify the tubular locus at which renal functions may be altered and to identify the mechanism by which functional changes are mediated. In the rat, Giebisch et al. (1964) found suppressed fractional reabsorption of sodium at the level of the distal tubule when hypertonic saline was administered, whereas suppressed proximal fractional reabsorption was found only when excreted sodium was greater than 13% of the filtered load. On the other hand, Cortney et al. (1965) …

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Contents Jan 1966

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, Winter 1966, Volume Two, Number Four.

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Determination Of Leukoagglutinin Specificity By In Vivo And In Vitro Studies, Ali A. Hossaini, Henry E. Wilson Jan 1966

Determination Of Leukoagglutinin Specificity By In Vivo And In Vitro Studies, Ali A. Hossaini, Henry E. Wilson

MCV/Q, Medical College of Virginia Quarterly

Results of testing sera from normal individuals and pathological patients, using a bromelin technique for the detection of leukoagglutinins, are reported. These results, supported further by an in vivo experiment, suggested that the phenomenon of leukoagglutination is immunologic in nature and that leukoagglutinins may be the cause of some febrile transfusion reactions. These are specifically directed against leukocytes, and do not involve the red cell series. Furthermore, the antigen (or antigens) is probably present in both the granulocytes and the mononuclear leukocytes. Anti-platelet antibodies could be presumed to be the cause of thrombocytopenia.

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Books Jan 1966

Books

MCV/Q, Medical College of Virginia Quarterly

Reviews of the following books: Ocular Syndromes, Walter J. Geeraets; Physiology and Biophysics of the Circulation, Alan C Burton; and Physiology of Respiration, Julius H. Comroe, Jr.

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Diabetic Microangiopathy, J. M. B. Bloodworth Jr. Jan 1966

Diabetic Microangiopathy, J. M. B. Bloodworth Jr.

MCV/Q, Medical College of Virginia Quarterly

Microangiopathy is the term applied to the abnormal state of the capillaries, arterioles, and venules found in the diabetic patient. It is characterized principally by thickening of the basement membrane of these small vessels. It might be worth mentioning that while we are concerned here with the smaller blood vessels, diabetic patients also show thickening of the basement membrane beneath the endothelium of arteries of all sizes. Also, the basement membrane-like material that surrounds each smooth muscle fiber in the wall of arteries shows similar thickening in diabetic patients. With this thickening, there is an increased glycoprotein content of the …

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Contributors Jan 1966

Contributors

MCV/Q, Medical College of Virginia Quarterly

List of contributors to this issue includes J. M. B. Bloodworth, Jr., Guy H. Chan, William F. Collins, Jr., Thaddeus S. Danowski, Max Ellenberg, Clay T. Gardner, Jr., David M. Hume, William R. Jordan, James M. Moss, John A. Owen, Jr., Olof H. Pearson, Thaddeus E. Prout, and H. St. George Tucker, Jr.

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Ernst Fischer: Thirty Years Of Service At The Medical College Of Virginia, Ernst G. Huf Jan 1966

Ernst Fischer: Thirty Years Of Service At The Medical College Of Virginia, Ernst G. Huf

MCV/Q, Medical College of Virginia Quarterly

Dedication essay by Ernst Huf to Dr. Ernst Fischer, who recently retired after thirty years of service to the Medical College of Virginia.

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Dynamic Physical Fitness And Body Composition, Archibald W. Sloan Jan 1966

Dynamic Physical Fitness And Body Composition, Archibald W. Sloan

MCV/Q, Medical College of Virginia Quarterly

Dynamic physical fitness may be satisfactorily estimated by the Harvard step test (modified for women) and this and other aspects of physical fitness are measured by appropriate test batteries. The percentage by weight of fat in the body may be calculated from the specific gravity or from caliper measurements of skin folds or ultrasonic measurements of the thickness of the layer of subcutaneous fat at selected sites. In general, physical education students are fitter than non-athletic students. British men students of physical education are fitter than American. International differences are less marked in non-athletic men and in women. Performance of …

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The Shame Of American Medicine--A Reply, David W. Richardson Jan 1966

The Shame Of American Medicine--A Reply, David W. Richardson

MCV/Q, Medical College of Virginia Quarterly

Reply to Elinor Langer's "The Shame of American Medicine" by David W. Richardson, M.D., Associate Professor of Medicine, Medical College of Virginia.

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Contributors Jan 1966

Contributors

MCV/Q, Medical College of Virginia Quarterly

List of contributors to this issue includes Rama M. Aiyawar, Hermann K. F. Blaschko, Ernest Bueding, Addison D. Campbell, Chalmers L. Gemmill, Ernest Gutmann, Gabriel Hilkovitz, Ernst G. Huf, Elinor Langer, Nancy S. LaPrade, John W. Moore, Richard W. Ramsey, Walther Riese, J. C. Rüegg, Alexander Sandow, Michael N. Sheridan, Archibald W. Sloan, Thomas C. Smith, Sidney Solomon, Harald Sonnenberg, Frederick J. Spencer, Sibyl F. Street, Alfred J. Szumski, William R. Tolbert, Hans H. Weber, and Priscilla M. Winn.

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Contents Jan 1966

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, Fall 1966, Volume Two, Number Three.

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Editorial: Responsibilities Of Scientists--A Closer Look, Fairfield Goodale Jr. Jan 1966

Editorial: Responsibilities Of Scientists--A Closer Look, Fairfield Goodale Jr.

MCV/Q, Medical College of Virginia Quarterly

From a reading of today's lay and scientific press, one must conclude that scientists are most important people. And, indeed, the signs of their beneficence are on every hand--rapid travel, instant communication, globe-encircling rockets, moon probes, food surpluses, longer life spans, and all manner of creature comforts which by now are taken for granted. Verily, ours is the age of scientific marvels and we are in the debt of those who have made it possible.

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The Future Effect Of The Computer And The Research Scientist On Medical Practice, Edward N. Brandt Jr. Jan 1966

The Future Effect Of The Computer And The Research Scientist On Medical Practice, Edward N. Brandt Jr.

MCV/Q, Medical College of Virginia Quarterly

The computer is here. It has become a part of medicine. We have talked for a day and a half now about some of the applications of computers in medicine, and of the future of at least some of these applications. There is a language problem in communicating with computers, but certainly the future is going to see a medical language, comparable to the scientific language Fortran, built to enable physicians to communicate with the computer. The real advancements in computer application depend at least in part upon active use by physicians of computers. In closing, let me summarize by …

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Cryocautery And Aqueous Humor Dynamics, Herbert Wiesinger Jan 1966

Cryocautery And Aqueous Humor Dynamics, Herbert Wiesinger

MCV/Q, Medical College of Virginia Quarterly

A method of cyclocryocautery, using the Kelman Cryostylet, is described. On rabbit eyes this brings about a statistically significant lowering of intraocular pressure and reduction of aqueous flow over an observation period of three months. The effects upon the facility of outflow are variable. Side effects are minimal. The intraocular temperature was measured at various points during and after cryocautery. An applicator temperature of about -40° C was found sufficient for the desired result with minimal side effects. Angiocryocautery of one or both long posterior ciliary vessels resulted only in a temporary reduction of intraocular pressure, as permanent obliteration of …

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Contents Jan 1966

Contents

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, Winter 1966, Volume One, Number Four.

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Reversible And Irreversible Effects Of Densely Ionizing Radiations Upon The Reproductive Capacity Of Cultured Human Cells, Paul Todd Jan 1966

Reversible And Irreversible Effects Of Densely Ionizing Radiations Upon The Reproductive Capacity Of Cultured Human Cells, Paul Todd

MCV/Q, Medical College of Virginia Quarterly

Some aspects of the radiosensitivity of single human cells have been examined in vitro. So far, all factors which tend to modify sensitivity to x-radiation appear not to modify (or to modify less effectively) the effects upon single cells of high-dE/dx radiation. Whenever the hazards of heavily ionizing radiations are being evaluated, chronic exposure must be considered equivalent to acute exposure, and any attempts to modify the effects of densely ionizing radiations at the cellular level are probably useless. In the case of cultured human cells, the RBE is dependent upon the endpoint because of the differently-shaped survival curves. Thus, …

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Contributors To This Issue Jan 1966

Contributors To This Issue

MCV/Q, Medical College of Virginia Quarterly

List of contributors to this issue includes Marvin J. Allison, Nabil A. Azzam, Ali A. Hossaini, George Kriegman, Brenda Payne, William M. Shanklin, John M. Smith, Paul W. Todd, Paul Tournier, and Henry E. Wilson.

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Volume One Subject Index Jan 1966

Volume One Subject Index

MCV/Q, Medical College of Virginia Quarterly

Subject index for MCV/Q, Medical College of Virginia Quarterly, Volume One.

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Pituitary Ablation For Diabetic Retinopathy, Olof H. Pearson Jan 1966

Pituitary Ablation For Diabetic Retinopathy, Olof H. Pearson

MCV/Q, Medical College of Virginia Quarterly

Our clinical experience and the experience of others seems to indicate that pituitary ablation can induce a significant beneficial effect on the course of diabetic retinitis, even in advanced stages. We have no strict criteria for the selection of patients. When surgical hypophysectomy is being done, the major restriction is whether the patient has a fair chance of getting through the procedure without great risk of death or serious complication. With yttrium-implant hypophysectomy, the risk of death from the procedure itself has been practically eliminated. The morbidity would be much less if the rhinorrhea and the threat of meningitis could …

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Cryosurgery Of The Pituitary Gland, William F. Collins Jr. Jan 1966

Cryosurgery Of The Pituitary Gland, William F. Collins Jr.

MCV/Q, Medical College of Virginia Quarterly

In closing I would like to state that I believe that with stereocryohypophysectomy we have a simple, effective technique which can be utilized to alter pituitary function. It can be performed under local anesthesia and, is a safe and effective method for aid in the control of diabetic retinopathy.

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Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 2 Jan 1966

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 2

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

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Observations On Chromaffin Tissue, Hermann K. F. Blaschko Jan 1966

Observations On Chromaffin Tissue, Hermann K. F. Blaschko

MCV/Q, Medical College of Virginia Quarterly

An attempt has been made to give in this article a review of some of our activities since I first met Ernst Fischer in Göttingen many years ago. I have not related the work of our laboratory to that of others. Also, I have only described observations made on chromaffin tissue. The catecholamines have acquired a much wider importance with their discovery in adrenergic neurones, and, more recently, in the central nervous system. However, the study of a more homogenous tissue has the advantage of greater simplicity. Some of the findings made on the adrenal medulla, e.g. the enzyme studies, …

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On The Nature Of The Resting Frog Skin Potential, Priscilla M. Winn, Nancy S. Laprade, William R. Tolbert, Ernst G. Huf Jan 1966

On The Nature Of The Resting Frog Skin Potential, Priscilla M. Winn, Nancy S. Laprade, William R. Tolbert, Ernst G. Huf

MCV/Q, Medical College of Virginia Quarterly

In this paper some of the highlights of research on the nature of the resting frog skin potential have been presented. Reviewing a period of about 30 years, it was the intention to show that several key problems have been recognized by a number of investigators who, through their experimental work, have tried to find unequivocal solutions to such problems as follows: a) The number and location of electrogenic layers (barriers) within the rather complex epidermis. b) The characterization of these barriers in terms of specific permeability properties. c) The electrical response of the two sides of the skin to …

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Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 3 Jan 1966

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 2 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

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Virus Infections--What Of The Future?, Robert J. Huebner Jan 1966

Virus Infections--What Of The Future?, Robert J. Huebner

MCV/Q, Medical College of Virginia Quarterly

The rate of progress in virus research today is so rapid that for many the present is the future. Consequently, in order to discuss the future in comprehensible fashion, I must talk about the present state of affairs--to discuss current knowledge which furnishes the basis for contemporary enormous interest in viruses. It is precisely those considerations which will furnish the springboard for future progress in understanding and controlling the effects of virus infections.

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The Pathogenesis Of Atherosclerosis And Coronary Heart Disease, Joseph T. Doyle Jan 1966

The Pathogenesis Of Atherosclerosis And Coronary Heart Disease, Joseph T. Doyle

MCV/Q, Medical College of Virginia Quarterly

Fifty-five percent of all deaths in the United States are ascribed to cardiovascular disease. The vast majority of these deaths are due directly or indirectly to atherosclerosis and its ischemic complications (Am. Heart Assoc., 1965; U.S. President's Commission on Heart Disease, Cancer and Stroke, 1964). Atherosclerosis is defined in Dorland's dictionary (24th edition) as "a lesion of large and medium-sized arteries with deposits in the intima of yellowish plaques containing cholesterol, lipoid material and lipophages." Typical atherosclerotic lesions of the coronary arteries are shown in figure 1. Even a casual inspection of these lesions shows the incompleteness of this conventional …

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Some Malpractices In Medical Statistics, James S. Kilpatrick Jr. Jan 1966

Some Malpractices In Medical Statistics, James S. Kilpatrick Jr.

MCV/Q, Medical College of Virginia Quarterly

Since it is now fashionable for papers in medical journals to contain statistical notations, it also follows that in a certain fraction of these the statistical content is wrongly applied. These malpractices may be classified as numerical, statistical, and methodological. To illustrate some of the most commonly occurring errors the following examples are given.

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Effects Of Computers On Patient Care, Jay Goldman Jan 1966

Effects Of Computers On Patient Care, Jay Goldman

MCV/Q, Medical College of Virginia Quarterly

In conclusion, the computer alone is not enough to provide the best possible patient care. Every hospital must be introspective about each patient-care system so that the performance aspects of the systems are meaningful and efficient. Couple the best methods of performance with the information processing and control capabilities offered by the computer, and one can envision a smoothly functioning patient-care complex in which the wild perturbations one sees in today's hospital operation are minimized. However, medical care finds itself in an awkward dichotomy. Many of the causes of system perturbation in the hospital are directly related to the demands …

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