Medicine and Health Sciences Commons^™

Caring For The Terminally Ill: Communicating With Patients And Family, Dana G. Cable

Henry Ford Hospital Medical Journal

Caring for terminally ill patients requires effective communication skills. It is important that medical personnel understand appropriate ways to communicate with the patient in order to inform him about his illness, throughout its duration. Physicians must develop an understanding of how patients communicate and ways to respond to that communication. Furthermore, the physician needs to communicate with the family of the terminally ill patient. Effective communication must become a regular part of the treatment.

Chronic Myelogenous Leukemia: Molecule To Man, Robert Peter Gale

Henry Ford Hospital Medical Journal

Chronic myelogenous leukemia (CML) is the best understood human cancer. The molecular basis of CML involves activation of a cellular proto-oncogene—ABL. The consequence is to increase tyrosine kinase activity. This results in a marked clonal increase in the myeloid mass. Later on, cellular maturation is blocked and the decrease eventuates in acute leukemia. Abnormalities of other proto-oncogenes or antioncogenes, like P53, may be involved in leukemia progression. Treatment of CML involves chemotherapy and, more recently, interferon. Whether this treatment prolongs survival or increases the likelihood of cure is unknown but either result seems unlikely. Bone marrow transplants which cure about …

Application Of The Polymerase Chain Reaction For Detection Of Minimal Residual Disease Of Hematologic Malignancies, Mark S. Roth, Valeri H. Terry

Henry Ford Hospital Medical Journal

Current induction therapies for acute and chronic leukemias and the lymphomas have achieved significant complete remission rates. Despite this initial success, disease recurrence remains a major problem. Relapse from clinically undetectable residual malignant cells is the most likely mechanism of recurrence. Of crucial importance to the clinician is the accurate detection of residual malignant cells prior to clinical relapse. Standard approaches to evaluate for this minimal residual disease (MRD) allow detection only when the malignant clone exceeds 1%. Patients in remission, however, may frequently have residual neoplastic cells that are far below this level. Recently, several investigators have adapted the …

Assessment Of Methylprednisolone Purging Efficacy On Daudi Burkitt Lymphoma Cells From Normal Bone Marrow, Nalini Janakiraman, Loreen M. Niewenhuis

Henry Ford Hospital Medical Journal

Studies on normal bone marrow and Daudi Burkitt lymphoma cells were performed to determine the efficacy of selective, in vitro chemopurging with methylprednisolone (MP). We found that MP reduces the numher of lymphoma cells without significant damage to bone marrow cells. This information is important because we need to improve the existing in vitro purging regimens used to cleanse autologous marrows of metastatic disease before transplantation into cancer patients who have received high-dose chemotherapy. Normal human bone marrow (NBM) and Daudi lymphoma cells were trealed in parallel with various purging regimens. NBM death was evaluated using soft-agar culture, while Daudi …

Capsaicin: A Therapeutic Option For Painful Diabetic Neuropathy, Karen M. Basha, Fred W. Whitehouse

Henry Ford Hospital Medical Journal

Fifteen patients with diabetes mellitus who had painful diabetic neuropalhy (PDN) were enrolled in a double-blind study to test the safety and efficacy of capsaicin 0.075% (Axsain, Genderm, Northbrook, IL). Twelve of the 15 patients completed the eight-week sludy. Nine of the 12 patients reported symptomatic relief; of these nine, five used the drug and four used the vehicle. The three patients who reported no relief of symptoms applied the vehicle. Capsaicin is potentially effective when burning pain is a major symptom of PDN. The side effects of capsaicin were limited and minimal. This agent should be considered by clinicians …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Quality Of Life: What Does It Mean?, Joyce A. Deshano

Henry Ford Hospital Medical Journal

No abstract provided.

Palliative Care In The 1990s: Special Issues, Derek Doyle

Henry Ford Hospital Medical Journal

No abstract provided.

New Purine Analogues For The Treatment Of Chronic B-Cell Malignancies, Thomas E. Gribbin

Henry Ford Hospital Medical Journal

Adenosine deaminase (ADA). a purine salvage pathway enzyme, appears to play a key role in normal lymphocyte growth, development, and differentiation. Three new purine nucleoside analogues, deoxycoformycin, fludarahine, and 2-chlorodeoxyadenosine, affect the normal function of the purine salvage pathway by inhibiting ADA or by acting as analogs of the ADA substrates. These agents show significant activity in the treatment of chronic B-cell leukemias and low-grade lymphomas. The pharmacology, mechanism of action, and clinical usefulness of these agents are discussed.

Peripheral Blood Stem Cell Transplantation As An Alternative To Bone Marrow Transplantation: An Overview, Nalini Janakiraman

Henry Ford Hospital Medical Journal

Stem cells capable of restoring hematopoiesis following lethal bone marrow injury circulate in the blood of many animals, including humans. When collected through leukapheresis and reinfused following high-dose chemotherapy, stem cells offer a treatment option not currently open to some patients who are unable to undergo autologous bone marrow transplantation because of tumor involvement in the pelvis, prior pelvic radiation, or intolerance to general anesthesia. After stem cell infusion, hematologic and immunologic recovery are rapid in comparison to that after autologous hone marrow reinfusion: however, in some cases platelet engraftment is slower. There is some evidence that tumor contamination in …

Porcine Bioprosthetic Aortic Valve Endocarditis With Ring Abscess And Aortic Stenosis, Reda A. Girgis, Howard Rosman, Ramon Del Busto, Maryann Fitzmaurice, Norman A. Silverman

Henry Ford Hospital Medical Journal

Porcine bioprosthetic valve endocarditis is an infrequent but serious complication of valve replacement surgery. Ring (or annular) abscess is a frequent finding in mechanical valve endocarditis. In contrast, porcine valve endocarditis most often involves the cusps, and annular infection is uncommon. Porcine valvular dysfunction secondary to endocarditis usually takes the form of incompetence, whereas stenosis is less frequent. We report a case of a 76-year-old female who developed endocarditis wilh Staphylococcus epidermidis nine months after placement of a Carpenter-Edwards porcine aortic valve. Her initial presentation included complete heart block and moderate aortic stenosis. Transesophageal echocardiography aided the diagnosis by demonstrating …

The Department Of Surgery And The Halsted Tradition, Edward R. Munnell

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Hospice Care: An Overview, Josefina B. Magno

Henry Ford Hospital Medical Journal

No abstract provided.

Classroom Interaction Between Teacherand Ctpb Medical Studentsfaculty Of Medicine, Chulalongkorn University, Boonnart Laisnitsarekul, Chaloem Varavithya, Seri Ruamsuke, Baterng Rajatapiti

Chulalongkorn Medical Journal

No abstract provided.

Changes In Sera Biochemistry And Hormones In Elderlythai Subjects : A Preliminary Report, Sukanya Werawatgoompa, Kalayanee Tunsaringkarn, Saichit Wongyai, Witoon Jaruprakorn, Kanit Buranasiri, Nikorn Dusitsin

Chulalongkorn Medical Journal

No abstract provided.

Elisa Seropositive Ocular Toxocariasis:A Case Report, Vilavan Puangsricharern, Pornsawat Nantawan, Malinee T. Anantaphruti

Chulalongkorn Medical Journal

No abstract provided.

The Development Of Mental Health Services In Sub-Saharan Africa: The Case Of Rwanda, Froduald Gatarayiha, Franz Baro, Morton O. Wagenfeld, Rene Stockman

The Journal of Sociology & Social Welfare

This paper considers several aspects of the evolution, organization and current status of the mental health system of Rwanda. The centerpiece of the Rwandan mental health system is the neuropsychiatric hospital in Ndera. Resource constraints preclude development of an extensive system of specialty mental health care. The World Health Organization has proposed that mental health services can best be delivered in developing countries through decentralization and integration with primary health care services. The accomplishments and problems encountered in implementing this model in Rwanda are described and, based on this experience, some recommendations are offered for other developing countries.

Mental Health Services In Hong Kong: History, Modern Development, And Issues, Wai-Kwong Mak

The Journal of Sociology & Social Welfare

This paper provides a comprehensive account of the history, current mental health services, and related-issues in Hong Kong. Psychiatric services provided by the Government such as inpatient, outpatient, and daypatient treatments are highlighted. Community mental health services rendered by the voluntary sector such as the counseling and casework, care in half-way houses, and psychiatric nursing are also discussed. Recent statistical information provides a detailed picture of psychiatric institutions and characteristics of patients. Mental health issues typical of developed countries are discussed.

A Cross-Cultural Perspective On Selected Mental Health Systems, Gary Mathews, Morton O. Wagenfeld

The Journal of Sociology & Social Welfare

The information provided from authors around the world on their respective mental health systems is analyzed and compared. Several key dimensions are utilized, including the relationship of mental health services to other services, institutional care, community care, staffing, prevention and mental health promotion services, and accessibility. Resources and governmental priorities are identified as being essential to the provision of effective services. It is clear that the general trends identified by the experts for mental health in both developing and developed countries are by no means universal in applicability.

Racial Differences In The Use Of Drugs And Alcohol Among Low Income Youth And Young Adults, John E. Poulin

The Journal of Sociology & Social Welfare

This study examines the use of drugs and alcohol among 284 youth and young adults of a low income urban community. Racial differences in the use of drugs and alcohol are examined for four age groups between 12 and 25.

Overall, the findings show significant racial differences in the use of both drugs and alcohol. Black youth and young adults have lower drug use and alcohol use rates than their white peers. The differences hold for the four age groups examined. Implications of the findings for drug prevention programs are discussed.

ข้อคิดเห็นบางประการเกี่ยวกับสุขภาพจิตและพฤติกรรม, Duangjai Kasantikul., Maneeratana Charungdechakul

Chulalongkorn Medical Journal

No abstract provided.

Family Therapy: Another Choice For Helping Children, U. Trangkasombat

Chulalongkorn Medical Journal

No abstract provided.

Characteristics Of Students Receiving Counselingcompared With Students In General, Duangjai Kasantikul, Bhirom Sughondhabirom, Umpon Su-Ampan

Chulalongkorn Medical Journal

No abstract provided.

Correlation Between Gestational Age And Ultrasoniccerebellar Diameter, Chanane Wanapirak, Theera Tongsong, Therdsak Rojsurakitti

Chulalongkorn Medical Journal

No abstract provided.

Renal Oncocytoma, Saowaneee Yenrudi, Vira Kasantikul, Ruangchai Vajarapongse, Santi Rojsatapong, Kaesorn Vajarapongse

Chulalongkorn Medical Journal

No abstract provided.

Pharmacological Treatment Of Psychiatric Disorders In Children And Adolescents, U. Trangkasombat

Chulalongkorn Medical Journal

No abstract provided.

Mental Health Services: An International Perspective, Thomas R. Holmes, Merl C. Hokenstad

The Journal of Sociology & Social Welfare

This paper provides an introduction to this special edition on international mental health perspectives. The importance of an international perspective is discussed and key questions are raised to provide the reader with a frame of reference for examining the mental health systems in the countries presented. An orientation to some of the current mental health issues in Europe, the United States, and developing countries is given as point of comparison for the reader. Questions discussed relate to the status of institutional care, outpatient services, the composition of mental health staff, the role of community interventions and prevention, and the availability …

Short Communication The Expression Of S-100 Protein In Canine Malignant Fibrous Histiocytoma (Mfh), Achariya Sailasuta, Tatsuya Fukatsu, Susumu Tateyama, Ryoji Yamag

The Thai Journal of Veterinary Medicine

No abstract provided.

การใช้ปริมาณน้ำนมที่จุดสูงสุดหลังคลอดทำนายปริมาณน้ำนมทั้งหมดที่จะได้ในหนึ่งช่วงของการให้นม, ปรียพันธุ์ อุดมประเสริฐ, พีระศักดิ์ จันทร์ประทีป, อุดม วังตาล

The Thai Journal of Veterinary Medicine

ปริมาณน้ำนมที่สูงสุด (PEAK) จะเกิดขึ้นประมาณ 40-70 วันหลังคลอด ซึ่งมีความสัมพันธ์กับปริมาณน้ำนมในหนึ่งช่วงของการให้นม (LTYIELD) อย่างมีนัยสำคัญทาง ยิ่งไปกว่านั้น PEAK ยังสามารถอธิบายความผันแปรของ LTYIELD ได้มากกว่า 95 เปอร์เซ็นต์ ความสัมพันธ์ดังกล่าวสำหรับแม่โคสาวท้องแรกสามารถแสดงอยู่ในรูปของ สมการคือ LTYIELD = 230 * PEAK (N = 37, P = 0.00, R2 = 0.97) ส่วนความสัมพันธ์สำหรับแม่โคท้องอื่น ๆ อยู่ในรูปของสมการ LTYIELD = 213 * PEAK (N = 63, P = 0.00, R2 = 0.98) การทราบถึงความสัมพันธ์ดังกล่าวจะช่วยให้ผู้เลี้ยงหรือสัตวแพทย์ สามารถตัดสินใจในการคัดโคสาวออกจากฝูงได้แต่เนิน ๆ โดยไม่ต้องรอให้โคสาวนั้นให้นมจนสิ้นสุด ช่วงการให้นมก่อน ช่วยในการจัดทำ Standard lactation shape เพื่อการวินิจฉัยปัญหาเกี่ยวกับการให้อาหารแม่โค หรือปัญหาเกี่ยวกับโรคที่เป็นแบบ subclinical นอกจากนี้ยังเป็นหลักฐานทางวิชาการที่ใช้อ้างอิงถึงความสูญเสียที่จะได้รับ อันเป็นผลเนื่องมา เลี้ยงดูแม่โคในช่วงหลังคลอดไม่ดีพอ ทำให้แม่โคไม่สามารถให้นมได้ถึงจุดสูงสุด