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Articles 52441 - 52470 of 63031

Full-Text Articles in Medicine and Health Sciences

The Effects Of Cyclophosphamide In The Absence And Precence Of Mesna On Some Blood Parameters In Guinea Pigs, Özdal Etli̇k, İlksi̇n Pi̇şki̇n, Vedat Sağmanligi̇l, Ahmet Tomur Jan 1999

The Effects Of Cyclophosphamide In The Absence And Precence Of Mesna On Some Blood Parameters In Guinea Pigs, Özdal Etli̇k, İlksi̇n Pi̇şki̇n, Vedat Sağmanligi̇l, Ahmet Tomur

Turkish Journal of Veterinary & Animal Sciences

This investigation was carried out to observe the effects of single dose of cyclophosphamide on blood cells and whether these could be prevented by mesna or not. In this study, 24 albino male guinea pigs weighing 250-300 g were equally diveded into 4 groups. The first (control) and second groups animals were applied physiologic saline as placebo while third and fourth group animals were given mesna (21.5 mg/kg) at 0, 180, 360 and 540^{th} minutes intraperitoneally. In addition these, physiologic saline was injected to the first and third group animals while cyclophosphamide (68,1 mg/kg) was given to the second and …


A Research On The Growth Rate On The Mullet (Mugil Auratus Risso, 1810) Fingerlings Fed Different Diets In Cages, Gülçi̇n Ağirağaç, Mustafa Kalma Jan 1999

A Research On The Growth Rate On The Mullet (Mugil Auratus Risso, 1810) Fingerlings Fed Different Diets In Cages, Gülçi̇n Ağirağaç, Mustafa Kalma

Turkish Journal of Veterinary & Animal Sciences

This research was conducted to determine the effect of different feeds on the growth rate of mullet juveniles (M. auratus R. 1810). Juveniles with a initial mean weight of 14.15 g and 14.71 g were feed a semi-moist diet (%50 trout viscera + %25 soybean meal + %25 high quality wheat bran) and carp pellets for a period of 60 days in marine cages. At the end of the experiment, final average weights were determined as 28.83± 0.6 g and 22.04±0.6 g have been obtained, respectively. The difference between the two harvesting weights was found statistically significant (P


Effect Of Bacteriocinogenic Starter Cultures On The Growth Of Listeria Monocytogenes In Turkish Fermented Sausage (Sucuk), İrfan Erol, T. Haluk Çeli̇k, Ufuk Tansel Şi̇reli̇, Haydar Özdemi̇r Jan 1999

Effect Of Bacteriocinogenic Starter Cultures On The Growth Of Listeria Monocytogenes In Turkish Fermented Sausage (Sucuk), İrfan Erol, T. Haluk Çeli̇k, Ufuk Tansel Şi̇reli̇, Haydar Özdemi̇r

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was the inhibition of L. monocytogenes (SLCC 9488) serotype 4b, indicated great importance in foodborne listeriosis, by using bacteriocin producer starter cultures as Pediococcus acidilactici PAC 1.0 and Lactobacillus sake Lb 706 in fermented Turkish sausage (sucuk), ripened at 20° and 25°C. For this purpose, 4 groups were constituted in each experimental sucuk producing as following. All of these groups were inoculated with L. monocytogenes at the range of 7.0 - 2.9x10^5 cfu/g, and the other groups except control group following starter cultures were added. 1.Group : Included only L. monocytogenes at the range of …


Nonlinear Approach To Characterization Oftemporomandibular Joint Vibrations, Murat Pehli̇van, Ahmet Saraçoğlu, Yeşi̇m Şahi̇n, Alexander Andrushchenko, Gürbüz Çelebi̇, Bi̇rgül Özpinar, Simin Hepguler, Berran Öztürk Jan 1999

Nonlinear Approach To Characterization Oftemporomandibular Joint Vibrations, Murat Pehli̇van, Ahmet Saraçoğlu, Yeşi̇m Şahi̇n, Alexander Andrushchenko, Gürbüz Çelebi̇, Bi̇rgül Özpinar, Simin Hepguler, Berran Öztürk

Turkish Journal of Medical Sciences

A new approach is proposed to characterize and discriminate temporomandi-bular joint vibrations. It consists of three steps. First, signals recorded during each cycle of mandibular movement are unified into a single time series. Second, this time series is embedded in some multidimensional space. Third, nonlinear analysis methods are applied to extract the pertinent signal characteristics. In this way two groups of signals have been characterized; those in the first group were recorded from patients whose post-treatment results werebad and the ones in the second group were recorded from patients whose post-treatment results were good. But patients in both groups had …


Frequency And Distribution Of Risk Factors Forcoronary Heart Disease In The Adult Populationof Rural District Of Elazığ, Turkey, Yasemi̇n Açik, R. Erol Sezer, Hafi̇ze Sezer Jan 1999

Frequency And Distribution Of Risk Factors Forcoronary Heart Disease In The Adult Populationof Rural District Of Elazığ, Turkey, Yasemi̇n Açik, R. Erol Sezer, Hafi̇ze Sezer

Turkish Journal of Medical Sciences

Objectives: This study was performed to determine the frequency and distribution of risk factors for coronary heart disease in people living in the Baskil district of Elazığ. Methods: From a population of 905 individuals aged 35 years and over, 388 were randomly selected. Selection of subjects was done with official records of the Baskil Health Care Center. Although repeated invitations were made, 32 individuals (29 men and 3 women) did not participate. Thus, 356 subjects were enrolled. Blood cholesterol and blood pressure levels, body height and weight were measured in all study subjects. In addition, a questionnaire was applied. Results: …


The Effect Of Hepatic Plexus Vagectomy On Thesphincter Of Oddi In Hummans, Osman Güler, Meti̇n Aydin, Muammer Karaayvaz, Osman Nuri̇ Di̇lek Jan 1999

The Effect Of Hepatic Plexus Vagectomy On Thesphincter Of Oddi In Hummans, Osman Güler, Meti̇n Aydin, Muammer Karaayvaz, Osman Nuri̇ Di̇lek

Turkish Journal of Medical Sciences

Right upper quadrant billary type pain is classified in three types. Biliary group lll patients have only biliary type pain that is due to sphincter of Oddi dyskinesia and without any abnormalities. In these patients, endoscopic sphincterotomy is a current treatment method that is performed to decrease the choledochal pressure and to facilitate bile flow into the duodenum. In this prospective study, the effect of hepatic plexus vagectomy as an adjunct to cholecystectomy on the sphincter of Oddi was investigated in biliary group lll patients who were potential sufferers of postcholecystectomy syndrome. Common bile duct pressures in 62 cholelithiasis patients …


Testicular Ultrasound And Biopsy Findings Incases Of Acute Lymphoblastic Leukemia, Ertan Kayseri̇li̇, Pami̇r Gülez, Sertaç Sözer Arslanoğlu, Canan Vergi̇n, Füsun Atlihan, Ragip Ortaç, Nazahat Argon, İrfan Karaca Jan 1999

Testicular Ultrasound And Biopsy Findings Incases Of Acute Lymphoblastic Leukemia, Ertan Kayseri̇li̇, Pami̇r Gülez, Sertaç Sözer Arslanoğlu, Canan Vergi̇n, Füsun Atlihan, Ragip Ortaç, Nazahat Argon, İrfan Karaca

Turkish Journal of Medical Sciences

No abstract provided.


Infantile Galactosialidosis Associated Withvitamin D Deficiency Rickets, Koray Boduroğlu, Ergül Tunçbi̇lek, Turgay Coşkun, Canan Uçar Jan 1999

Infantile Galactosialidosis Associated Withvitamin D Deficiency Rickets, Koray Boduroğlu, Ergül Tunçbi̇lek, Turgay Coşkun, Canan Uçar

Turkish Journal of Medical Sciences

Galactosialidosis is an autosomal recessive disease with combined deficiency of two lysosomal enzymes due to the lack of a protective protein. We report on a boy with infantile galactosialidosis who has an intermediate phenotype and vitamin D deficiency rickets. Due to the possible role of vitamin D deficiency in the pathogenesis of dysostosis multiplex we recommend that patients with lysosomal storage disease should be supplemented with vitamin D.


Chromosomal Aberrations In Peripherallymphocytes Of A High-Voltage Power Linemanexposed To Electromagnetic Fields, M. Emi̇n Erdal, Nurten Erdal, Si̇bel Oğuzkan Jan 1999

Chromosomal Aberrations In Peripherallymphocytes Of A High-Voltage Power Linemanexposed To Electromagnetic Fields, M. Emi̇n Erdal, Nurten Erdal, Si̇bel Oğuzkan

Turkish Journal of Medical Sciences

No abstract provided.


Arginine Hydrolysis By Mycoplasma Fermentansisregulated By Glucose, Sema Aşkin Özcan Jan 1999

Arginine Hydrolysis By Mycoplasma Fermentansisregulated By Glucose, Sema Aşkin Özcan

Turkish Journal of Medical Sciences

Arginine metabolism by mycoplasmas has been reported to be correlated with pathogenicity. Since a clinically important mycoplasma; M. fermentans hydrolyses arginine as an energy source, the arginine metabolism amongst M. fermentans strains belonging to different isolation sites was investigated. Arginine hydrolysis was detected by the increase in NH 4+ concentration, measured using an NH 4+ -sensitive electrode. The method proved simple to use and gave reproducible results. In broth medium, arginine and glucose were both shown to act as energy sources for growth. It was also shown that, in contrast to previous work, glucose inhibited arginine hydrolysis during growth. There …


In Vitro Effects Of Some Anthelminthics On Themalate Dehydrogenase And Lactate Dehydrogenaseenzyme Activities Of Taenia Saginata, A. Yasemi̇n Öztop, Gülendame Saygi, H. Nursevi̇n Öztop Jan 1999

In Vitro Effects Of Some Anthelminthics On Themalate Dehydrogenase And Lactate Dehydrogenaseenzyme Activities Of Taenia Saginata, A. Yasemi̇n Öztop, Gülendame Saygi, H. Nursevi̇n Öztop

Turkish Journal of Medical Sciences

Malate Dehydrogenase (MDH) and Lactate Dehydrogenase (LDH) activities were demonstrated in the mitochondrial and cytosolic fractions of an intestinal cestode, Taenia saginata, and then the in vitro effects of three anthelminthics, albendazole, niclosamide, and piperazine on these enzymes were investigated. The Vmax and Km values of MDH were found to be 3.00 \mumol (min mg protein) -1 and 0.0166 mM respectively. In vitro addition of albendazole and niclosamide increased the Vmax value of MDH, whereas it decreased Km value of MDH (p


Very Late Relapse In Hodgkin's Disease, İmdat Di̇lek, Günhan Gürman, Işinsu Kuzu, Seli̇m Erekul Jan 1999

Very Late Relapse In Hodgkin's Disease, İmdat Di̇lek, Günhan Gürman, Işinsu Kuzu, Seli̇m Erekul

Turkish Journal of Medical Sciences

No abstract provided.


The Intracellular Concentration Of Components Ofthe Ubiquitin System In A549 Culture Cellsduring Uv Treatment, İbrahi̇m Pi̇ri̇m Jan 1999

The Intracellular Concentration Of Components Ofthe Ubiquitin System In A549 Culture Cellsduring Uv Treatment, İbrahi̇m Pi̇ri̇m

Turkish Journal of Medical Sciences

This study attempts to determine a link between the intracellular components of the ubiquitin (Ub) system and the process of DNA repair in eukaryotes. It is possible to investigate this link in two ways: i. studying the concentration of mRNA for specific Ub components in DNA damaged and controlled cells. ii. studying the concentration of proteins of the Ub system in both DNA damaged and control cells. The specific aim of this study was to try to establish such a link between repair and Ub, by studying and making a quantitative analysis of the intracellular concentrations of both the Ub …


A Combined Variation In The Gluteal Region, Zeli̇ha Kurtoğlu, M. Haluk Uluutku Jan 1999

A Combined Variation In The Gluteal Region, Zeli̇ha Kurtoğlu, M. Haluk Uluutku

Turkish Journal of Medical Sciences

No abstract provided.


Hepatic Macronodular Tuberculosis, İlgi̇nç Yorulmaz, Hakan Uncu, Yalçin Aker, Aslan Sakarya, Aydin Isisag Jan 1999

Hepatic Macronodular Tuberculosis, İlgi̇nç Yorulmaz, Hakan Uncu, Yalçin Aker, Aslan Sakarya, Aydin Isisag

Turkish Journal of Medical Sciences

No abstract provided.


S-Aroylmethyl N, N-Disubstituteddithiocarbamates With Antiparkinson Activity, Rahi̇me Şi̇mşek, Ci̇hat Şafak, Kevser Erol, Kami̇l Vural Jan 1999

S-Aroylmethyl N, N-Disubstituteddithiocarbamates With Antiparkinson Activity, Rahi̇me Şi̇mşek, Ci̇hat Şafak, Kevser Erol, Kami̇l Vural

Turkish Journal of Medical Sciences

Seven S-aroylmethyl N,N-disubstituted dithiocarbamate derivatives have been synthesized and their effects on oxotremorine induced tremor have been investigated on mice pretreated with the proparkinsonian drug haloperidol. While the compound 1f inhibited oxotremorine-induced tremors at doses of 50 mg/kg and 100 mg/kg levels, compounds 1a, 1c and 1e had this effect at the dose of 100 mg/kg. The compounds 1b, 1d and 1g had no effect on oxotremorine-induced tremors in mice. These results suggest that some of these derivatives have central antimuscarinic effects and antiparkinson activities.


An Immunohistochemical Study Of Gastricneuroendocrine Tumors: Expression Ofproliferating Cell Nuclear Antigen Andp53 Oncoprotein, Gülen Doğusoy, Süha Göksel, Işil Paki̇ş, Haydar Durak, Gökhan Ersoy, Selda Göçener Jan 1999

An Immunohistochemical Study Of Gastricneuroendocrine Tumors: Expression Ofproliferating Cell Nuclear Antigen Andp53 Oncoprotein, Gülen Doğusoy, Süha Göksel, Işil Paki̇ş, Haydar Durak, Gökhan Ersoy, Selda Göçener

Turkish Journal of Medical Sciences

The aim of this study is to examine expression of Proliferating cell nuclear antigen (PCNA) and p53 oncoprotein in gastric neuroendocrine tumors. 35 gastric neuroendocrine tumors were analyzed for first histopathologic features and then, immunohistochemical study was done to detect labeling index of PCNA and accumulation of p53 protein by using monoclonal antibodies and the Labeled strepavidin-biotin method. PCNA labeling index and p53 protein expression were compared with histopatholoic features in statistical methods of Fisher's exact, chi square and logistic regression tests. No significant correlation was found between them except PCNA score and depth of invasion. In conclusion, our findings …


Bilateral Carpal Hyperextension Cases In Dogs And Operative Treatment Methods, Burhanettin Olcay, Mehmet Sağlam, Hasan Bi̇lgi̇li̇ Jan 1999

Bilateral Carpal Hyperextension Cases In Dogs And Operative Treatment Methods, Burhanettin Olcay, Mehmet Sağlam, Hasan Bi̇lgi̇li̇

Turkish Journal of Veterinary & Animal Sciences

This study was carried out on 4 dogs with bilateral carpal hyperextension that treated in Ankara University, Faculty of Veterinary Medicine Orthopaedics and Traumatology Clinic. In clinical examination, it was found that the angle of the stepped carpal joints were between 250° and 270°. Furthermore, there were wounds at volar sites of carpal joints. There were no lesions seen radiographically. In 3 cases, total arthrodesis was made by applying a single Steinmann pine, passing intramedullary through metacarpus III, to os carpi centrale and radius, in one case total arthrodesis was made by applying three Steinmann pines passing through metacarpus 2, …


Effect Of Gonadoreline Administration On Blood Progesterone, Oestradiol 17\Beta Concentrationand Some Fertility Parameters In Angora Goats, Erol Alaçam, Bülent Güven, Ali Ayar, Erdal Saban Jan 1999

Effect Of Gonadoreline Administration On Blood Progesterone, Oestradiol 17\Beta Concentrationand Some Fertility Parameters In Angora Goats, Erol Alaçam, Bülent Güven, Ali Ayar, Erdal Saban

Turkish Journal of Veterinary & Animal Sciences

Various fertility parameters, plasma progesterone and oestradiol 17\beta ?concentrations were investigated in Angora Goats receiving gonadoreline immediately or on 12th day after breeding . A total 48 cyclic , pluriparous Angora Goats, 2-5 years of age were divided into 3 groups. The first group received 100 µg gonadorelin immediately after breeding. The second group received 100 µg gonadoreline on the 12th day after breeding and the third group receiving no injection served as the control. Jugular blood samples were collected from all goats during the days 13 to 16 after breeding and plasma progesterone and oestradiol 17\beta?levels were determined by …


Efficacy Of Moxidectin Against Gastrointestinal Nematodesin Naturally Infected Lambs And Calves, Erkut Tüzer, Müfi̇t Toparlak, Kazim Göksu Jan 1999

Efficacy Of Moxidectin Against Gastrointestinal Nematodesin Naturally Infected Lambs And Calves, Erkut Tüzer, Müfi̇t Toparlak, Kazim Göksu

Turkish Journal of Veterinary & Animal Sciences

In this trial based on the reduction of the egg output and on the evaluation of results from larval/egg differentiation, moxidectin (Cydectin, 1% injectable moxidectin) administrated subcutaneously at a dose of 0.2 mg kgbw -1 was found effective on the gastrointestinal nematodes in naturally infected lambs (8 female and 7 male treatment; 8 female and 7 male control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp and Nematodirus spp and in naturally infected female calves (20 treatment and 10 control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp, Bunostomum sppand Cooperia spp.The efficacy was 100% on day +7, 99.9% on day +14 …


The Use Of Laboratory Findings In The Diagnosis Of Ceh-Pyometra Complexin The Bitch, Mustafa Kaymaz, Ayhan Baştan, Ni̇l Erünal, Seli̇m Aslan, Murat Findik Jan 1999

The Use Of Laboratory Findings In The Diagnosis Of Ceh-Pyometra Complexin The Bitch, Mustafa Kaymaz, Ayhan Baştan, Ni̇l Erünal, Seli̇m Aslan, Murat Findik

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to research the effects of ultrasonography, vaginal cytology, a serum biochemical profile, complete blood count and blood gas analysis in 18 bitches in the diagnosis of cystic endometrial hyperplasia (CEH)-pyometra complex. In transabdomimal ultrasonography, it was observed the the majority of anechongenic areas differed with the thickness of the uterine wall. Usually basal-parabasal type of cells appeared in vaginal cytologic examination, invasion of neutrophyl leucocytes and in some cases degenerative cell changes proved inflammatory changes. In bitches with CEH-pyometra complex there was a very significant increase in AST (Aspartate aminotransferase) and decrease in the …


The Location Of Extrinsic Afferent And Efferent Neurons Innervatingthe Stomach And Colon In Rat, Berri̇n Gençer Tarakçi, Camille Vaillant Jan 1999

The Location Of Extrinsic Afferent And Efferent Neurons Innervatingthe Stomach And Colon In Rat, Berri̇n Gençer Tarakçi, Camille Vaillant

Turkish Journal of Veterinary & Animal Sciences

The location of extrinsic afferent and efferent neurons projecting to the rat gastrointestinal tract were mapped using the retrograde tracer, True Blue (TB). Injection of retrograde tracer, TB into stomach, proximal colon and distal colon resulted in labelled cells in the dorsal root ganglia. Cells were also labelled in the nodose ganglia following injection of tracer into stomach and proximal colon. TB-labelled cells were also seen in the prevertebral ganglia (coeliacomesenteric complex and inferior mesenteric ganglion), after injection of TB into the stomach, proximal and distal colon. Many TB-labelled cells were detected in the dorsal motor nucleus of the vagus …


Therapy Of Knemidocoptic Mange In Budgerigars With Spot-On Applicationof Moxidectin, Müfi̇t Toparlak, Erkut Tüzer, Ayşen Gargili, Aynur Gülanber Jan 1999

Therapy Of Knemidocoptic Mange In Budgerigars With Spot-On Applicationof Moxidectin, Müfi̇t Toparlak, Erkut Tüzer, Ayşen Gargili, Aynur Gülanber

Turkish Journal of Veterinary & Animal Sciences

In this study, 30 Budgerigars ( Melopsittacus undulatus) with Knemidocoptes pilae infection were treated with a spot-on application of moxidectin (Cydectin® Injection For Cattle) at a dose of 1 mg (0.1 ml Cydectin) per bird. This application was given once to 10 birds and twice at 10 days intervals to 20 birds. Clinical signs in all birds of both groups disappeared 30-40 days after treatment. No side effects were seen.


The Morphologicial Investigations Of Experimental Avian Encephalomyelitis In Turkey Embriyo, Fethi̇ Yilmaz, Harun Özer Jan 1999

The Morphologicial Investigations Of Experimental Avian Encephalomyelitis In Turkey Embriyo, Fethi̇ Yilmaz, Harun Özer

Turkish Journal of Veterinary & Animal Sciences

In this study; macroscopic and microscopic changes induced by Avian Encepholomyelitis Virus (AEV) in turkey embryos were investigated. For purpose 0,1 ml. AEV-VR (Van Roekel Strain) at Embriyo Infective Dose 50 of 10 -3 diluted in steril saline at 1/10 ratio was inoculated into 7-day-old emriyonated turkey eggs via yolk sac. The most prominent macroscopic findings were loss of embryo movements, retardation in growth, cerebral edema, torticollis, cataract, deformities in the leg and feed. Microscopic lesions characterized by vascular proliferation, edema, gliosis, neuronal necrosis and degeneration in the brain, gliosis, neuronal degeneration and necrosis, in medulla spinalis, cataract in the …


Effects Of Selection For Four Week Body Weight On Reproductiveperformance In Japanese Quail, Levent Türkmut, Özge Altan, İsmai̇l Oğuz, Servet Yalçin Jan 1999

Effects Of Selection For Four Week Body Weight On Reproductiveperformance In Japanese Quail, Levent Türkmut, Özge Altan, İsmai̇l Oğuz, Servet Yalçin

Turkish Journal of Veterinary & Animal Sciences

This research was carried out to determine the genetic effects of divergent selection under two different selection pressures for four week body weight over three generations on reproductive characteristics and some egg characteristics in Japanese quail. Birds were weighed individually. Individual selection for body weight was carried out at four weeks, separately for each sex. The proportion kept was 10% for males and 30% for females in 10Y and 10D lines, and 20% for males and 60% females in 20Y and 20D lines. 10Y and 20Y lines were selected for high body weight, 10D and 20D lines were selected for …


Urinary Serotonin And 5-Hydroxyindolacetic Acid Levels In Preeclampsia, Pervi̇n Vural, Cemi̇l Akgül, Mukaddes Canbaz, Alkan Yildirim Jan 1999

Urinary Serotonin And 5-Hydroxyindolacetic Acid Levels In Preeclampsia, Pervi̇n Vural, Cemi̇l Akgül, Mukaddes Canbaz, Alkan Yildirim

Turkish Journal of Medical Sciences

The role of serotonin in the pathogenesis of hypertension which is one of the main symptoms of preeclampsia is of growing importance. The levels of serotonin (5-Hydroxytryptamin or 5-HT) and its metabolite, 5-Hydroxyindolacetic acid (5-HIAA) in twenty-four hour urine samples taken from severe preeclamptic and normotensive pregnant women were determined by colon chromotography and spectrophotometry. In preeclamptic pregnant women there was a significant increase in 5-HT levels (P


The Dermatophytic Flora Ratio Of Dermatophytes, Hüseyi̇n Taniş, Gürbüz Aksoy, Zülal Aşçi Jan 1999

The Dermatophytic Flora Ratio Of Dermatophytes, Hüseyi̇n Taniş, Gürbüz Aksoy, Zülal Aşçi

Turkish Journal of Medical Sciences

This paper describes the mycological examination of patients admitted to the department of dermatology of Kahramanmaras State Hospital. One hundred and seventy samples of finger nails, hairs and skin were collected from patients suspected of having fungal diseases and were examined under a light microscope after being treated with 15-20% KOH solution. It was observed that 68 of the 170 samples contained fungal hyphae and arthrospores, while 62 samples were free of these. Forty samples were observed to have Malasezia furfur. The samples containing M. furfur were not subjected to a culture medium. Of the 130 cultured samples, 68 had …


Focal Dermal Hypoplasia (Goltz Syndrome) In Amale Infant, Hülya Bi̇lgen, Eren Özek, Cengi̇z Canpolat, Oya Gürbüz, Müyesser Tuncer Jan 1999

Focal Dermal Hypoplasia (Goltz Syndrome) In Amale Infant, Hülya Bi̇lgen, Eren Özek, Cengi̇z Canpolat, Oya Gürbüz, Müyesser Tuncer

Turkish Journal of Medical Sciences

No abstract provided.


Prevalence Of Diabetic Nephropathy In Turkish Children With Insulin-Dependent Diabetes Mellitus, Ayşenur Ökten, Gülay Kaya, Gülay Karagüzel, Yusuf Gedi̇k, Muhterem Özdemi̇r Jan 1999

Prevalence Of Diabetic Nephropathy In Turkish Children With Insulin-Dependent Diabetes Mellitus, Ayşenur Ökten, Gülay Kaya, Gülay Karagüzel, Yusuf Gedi̇k, Muhterem Özdemi̇r

Turkish Journal of Medical Sciences

This study was involved with determining the prevalence of diabetic nephropathy in 72 Turkish children with insulin-Dependent diabetes mellitus. Diabetic nephropathy was diagnosed with blood pressure levels, glomerular filtration rate, albumin excretion rate, ?-2 microglobulinuria and kidney length. There wereo significant differences between laboratory data for boys and girls, but adolescent patients had significantly higher albumin excretion rates than preadolescent patients (p


Diurnal Variation Of Methotrexatepharmacokinetics In Adults With Osteosarcoma, Necdet Soykan, Mehtap Çinar, Cenk Can, Banu Çiçek Bi̇lkay Jan 1999

Diurnal Variation Of Methotrexatepharmacokinetics In Adults With Osteosarcoma, Necdet Soykan, Mehtap Çinar, Cenk Can, Banu Çiçek Bi̇lkay

Turkish Journal of Medical Sciences

The daytime and nighttime dispositions of high dose (12 g/m 2 ) methotrexate were examined in 8 osteosarcoma patients. The plasma and renal clearances, urine pH values and area under the curves were compared. The plasma clearance of methotrexate tended to fall after it was administered at (from 1.74±0.06 ml/min/kg to 0.47±0.01 ml/min/kg, p