Medicine and Health Sciences Commons^™

J Am Coll Dent 2017 84 2

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.

J Am Coll Dent 2017 84 1

Journal of the American College of Dentists

The Journal of the American College of Dentists (JACD) publishes scholarly articles, editorials, essays, and reflections addressing the ethical, professional, and social dimensions of dentistry. The Journal serves as a forum for advancing ethics, professionalism, leadership, and excellence within the dental community. By fostering dialogue across disciplines and perspectives, JACD provides readers with insights that encourage ethical, professional practice, lifelong learning, and service to the public, reinforcing dentistry’s commitment to advancing oral healthcare and the common good.

Ultrasound Evaluation Of Left Ventricular Function In Coronary Artery Ectasia: The Added Value Of 2d Speckle-Tracking Echocardiography, Osama Abouelfetouh Elshaer, Mahmoud Gomaa, Ramy Magdy Elgamal, Mohamed Shokry Fahmy, Reda Nabil Dawoud, Reda Biomy, Ahmed Mostafa Ahmed, Mohamed Kamal Salama

Journal of the Saudi Heart Association

Introduction: Coronary artery ectasia (CAE) is defined as abnormal dilatation of coronary arteries and may be linked to subclinical myocardial dysfunction. Conventional echocardiographic parameters may not adequately detect early left ventricular (LV) dysfunction. Two-dimensional speckle-tracking echocardiography (2D STE) has shown promise in identifying subtle myocardial changes.

Methods: In this single-center observational study, 90 participants with available coronary angiography were divided into three groups: Group A (controls, n=30), Group B (single-vessel CAE, n=30), and Group C (multi-vessel CAE, n=30). Standard echocardiographic indices including LV ejection fraction (LVEF), volumes, and diastolic function were assessed. Global radial, longitudinal, circumferential, and area strains were …

Effect Of Ingot Thickness And Translucency Of Lithium Disilicate Glass-Ceramic And Final Shade: An In Vitro Study, Rami Shurbaji Mozayek, Even Hanifi, Hiba Al Helou, Mohammed Yamen Al Shorbaji Al Moziek, Nour Al Deen Kharboutly

International Arab Journal of Dentistry

Introduction: laminate veneers can alter the final shade depending on factors like resin cement shade or material used. Other factors such as ceramic thickness and translucency will be discussed in this study.

Methods: The study sample consists of 60 discs made of lithium disilicate glass ceramic divided into four groups (HT, LT, MO, HO) according to their translucency, each group was subsequently divided into three subgroups (1, 0.75, 0.5 mm) according to their thickness. L, a,b values were measured for each disc. One-Way ANOVA was carried out with 95% confidence interval.

Results: Statistical analysis showed significant difference …

Cytotoxicity And Osteogenic Potentials Of Mesenchymal Stem Cells Via A Novel Formulation Of Mineral Trioxide Aggregate: An In Vitro Study, Ahmed Elgendi, Ehab Hassanien, Mohamed Nagy, Iman Fathy, Ashraf Abu Seida, Elhassan Hassanein

International Arab Journal of Dentistry

Objectives: Root perforations can lead to periodontitis and alveolar bone loss. This study compared cytotoxicity and osteogenic potential of zirconia-containing mineral trioxide aggregate (MTA) Matreva (MAT group) to MTA Angelus (ANG group) as root perforation repair materials.

Methods: Bone marrow mesenchymal stem cells (BM-MSCs) were extracted from two albino rats and cultivated. The cytotoxicity of the studied materials was determined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay at three time points: 3, 7, and 14 days. The evaluated materials were employed to guide the osteogenic differentiation of BM-MSCs into osteoblasts. The osteogenic impact was evaluated by assessing calcium …

Assessment Of External Root Resorption During The First Stage Of The Orthodontic Treatment: A Prospective Cone-Beam Tomography Study, Eliana Pineda Vélez

International Arab Journal of Dentistry

Introduction: predisposition to root resorption as a result of a dental movement may be a consequence of clinical, biological, and biomechanical factors that should lead the clinician to objectively assess each patient to reduce associated risk factors.

Objectives: to establish an association between clinical and tomographic findings related to external root resorption (ERR) using cone beam tomography (CBCT) on maxillary incisors during the first stage of the orthodontic treatment. Methods: an observational, follow-up, cohort study that analyzed the association between clinical and radiographic variables on maxillary incisors using CBCT before placing fixed orthodontic appliances and finishing the first …

Evaluation Of Anti-Bacterial Efficacy Of Ginger, Resin Gum, And Nigella Sativa Irrigants Against Enterococcus Faecalis: An In Vitro Study, Iman El Ghazzawy, Leen Imad Hasbini, Reem Chamseddine, Wael Betbout, Roula Abiad

International Arab Journal of Dentistry

Objectives: To evaluate the antibacterial efficacy of Ginger, Resin Gum, and Nigella Sativa, against Enterococcus Faecalis.

Methods: Thirty-eight extracted single-rooted premolars were inoculated with E.faecalis, except the negative control, and incubated for 4 weeks. After instrumentation samples were divided into 4 groups (n=7) according to final irrigation: NaOCl+EDTA (Group A), Nigella sativa (B), Resin Gum (C), Ginger (D), plus 2 control groups (n=5): Saline (E), and Saline without bacterial inoculation (F). Cultures were collected at baseline and after irrigation.

Results: One-way ANOVA showed that in groups A-D a statistically significant reduction of bacterial load was observed at …

Allergy In Dentistry: Mechanisms Of Development And Effective Treatment Methods, Maria Zofia Lisiecka

International Arab Journal of Dentistry

Objectives: This study is conducted to analyse the mechanisms of allergic reaction development in dentistry and the effectiveness of their treatment methods.

Methods: During it, a review of current scientific sources on allergology, immunology, dentistry, pharmacology, and materials science is conducted, mechanisms for the development of allergies of various types are established, the effectiveness of treatment methods is evaluated, and clinical recommendations for allergy therapy in dentistry are formed.

Results: The results show that the development of allergic reactions occurs by two mechanisms. Immediate-type immunoglobulin E-mediated (IgE-mediated) responses are triggered by the release of histamine, serotonin, and …

Sickle Cell Anemia And Its Impact On The Oral Cavity: Integrative Review, Fernanda Leal, Maria Inês Guimarães, Ambre Natbeth, Inês Lopes Cardoso

International Arab Journal of Dentistry

Introduction: Sickle cell anemia, a hereditary disease, results from a mutation in the β-globin coding gene that makes up hemoglobin, leading to the deformation of erythrocytes. Numerous oral manifestations result from this disease; however, some may not be specific.

Objectives: This study’s objective is to recognize these clinical manifestations of the disease to be able to manage oral health in sickle cell anemia patients.

Methods: this integrative review analyzes scientific literature on the impact of sickle cell anemia on oral cavity. A bibliographic search was performed in PubMed, ScienceDirect, CINAHL Plus (via EBSCO host), Web of Science …

Impact On Oral Health Of The Post-Covid-19 Infections: A Systematic Review, Aouatif Aouidate, Hanane Ouddoud, Loubna Bahije

International Arab Journal of Dentistry

Introduction: The COVID-19 pandemic has been associated with a diverse range of oral health implications, including mucosal lesions, periodontitis, and disruptions of the oral microbiota. Since airborne particles primarily transmit COVID-19, understanding its potential impact on oral health is crucial for dental care and infection control.

Objectives: This systematic review aimed to evaluate the effects of post-COVID-19 infections on oral health, highlighting clinical manifestations, periodontal disease associations, and microbiota disturbances.

Methods: Electronic literature searches were conducted between January 2020 and July 2024 by one author across several databases, including PubMed/MEDLINE, Scopus, Cochrane Library, EMBASE, ScienceDirect, Google Scholar, …

Knowledge And Attitudes About Epilepsy Of Neurology Outpatients In Türkiye, Ayşe Pinar Ti̇ti̇z, Abi̇di̇n Erdal, Yaren Ağar, Buse Altunbaşak

Turkish Journal of Medical Sciences

Background/aim: We aimed to evaluate the level of epilepsy-related knowledge and attitude among neurology outpatients without an epilepsy diagnosis.

Materials and methods: The Epilepsy Knowledge and Attitude Scale was applied to 331 adult patients who were evaluated with various diagnoses in the neurology outpatient clinic.

Results: The participants comprised 331 people, 51.4% of whom were women and 48.6% of whom were men. The knowledge and attitude values increase significantly as the education level of our participants increased (p < 0.001). The knowledge and attitude scores of those who knew about an individual with epilepsy were significantly higher (p < 0.001). Attitude scale scores were higher in patients diagnosed with headache, multiple sclerosis, syncope, Behçet’s disease, essential tremor and sleep disorders compared with other groups.

Conclusion: This study focused on a subgroup of adults without epilepsy who had other neurological conditions. The findings may illuminate the critical …

Anthropometric And Metabolic Assessment In Adults With Down Syndrome: The Need For Novel Indices And Tailored Criteria ​, Seli̇n Teki̇n, Nergi̇s Basmaci, İnci̇lay Lay, Alper Gürlek

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the metabolic profile of adults with Down syndrome (DS) using novel anthropometric and metabolic indices, while also highlighting the limitations of traditional obesity assessment methods compared with the non-DS population.

Materials and methods: This cross-sectional study included 22 adults with DS and 28 age- and sex-matched non-DS controls. Anthropometric measurements, including BMI, waist circumference (WC), and hip circumference (HC), were recorded alongside novel indices such as waist-to-height ratio (WHtR), body adiposity index (BAI), A body shape index (ABSI), and visceral adiposity index (VAI). Metabolic parameters (fasting plasma glucose, HbA1c, lipid profiles, HOMA-IR) and CBC-derived …

Association Between Nutritional Targets And Muscle Index Changes In Patients With Terminal Cancer Under Palliative Care ​, İrem Kiraç Utku, Burcu Çalişkan Aydoğmuş, Hati̇ce Nur Avcioğlu, Müge Çatikkaş, Ayfer Durak, Deni̇z Sevi̇ndi̇k Günay, Umut Safer

Turkish Journal of Medical Sciences

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Background/aim: Malnutrition and muscle wasting are common in terminal cancer patients and adversely affect prognosis. Bedside muscle ultrasonography (US) has emerged as a practical tool to assess nutritional status and monitor therapy. This study evaluated the relationship between achieving individualized nutritional targets and changes in muscle indices measured by US in terminal cancer patients receiving palliative care.

Materials and methods: Subcutaneous fat tissue thickness (SFTT), muscle thickness (MT), and cross-sectional area (CSA) of the rectus femoris (RF) and biceps brachii (BB) muscles were assessed by US over 10 days and normalized to height squared (m²). A total of 95 …

Contribution Of Genetic Test Results To Patient Management In Ophthalmology: Results From A Turkish Stargardt Disease Cohort ​, Fulya Yaylacioğlu Tuncay, Şengül Özdek, Burak Acar, Gülsüm Kayhan, Murat Yüksel, Hüseyi̇n Baran Özdemi̇r, İhsan Gökhan Güreli̇k, Mehmet Ali̇ Ergün

Turkish Journal of Medical Sciences

Background/aim: The aim of the study was to analyze the genotype and phenotype characteristics of Turkish patients with a clinical diagnosis of Stargardt disease and to evaluate how collaboration between the departments of medical genetics and ophthalmology contributes to patient management.

Materials and methods: The clinical findings, genetic testing workflow in the medical genetics department, and the genetic testing results of patients clinically diagnosed with Stargardt disease in the ophthalmology department were retrospectively analyzed.

Results: The study included 50 patients from 46 families. The genetic test reports confirmed the clinical diagnosis of Stargardt disease type 1 (STGD1) in 27 patients …

Reliability Of Handheld Autorefractometers In Patients After Cataract Surgery ​, Ayça Küpeli̇ Çinar, Abdulkadi̇r Can Çinar, Hande Güçlü

Turkish Journal of Medical Sciences

Background/aim: Accurate postoperative refraction assessment is essential for optimal visual rehabilitation after cataract surgery. Although handheld autorefractometers (HH-ARMs) are widely used in pediatric and uncooperative patients, their reliability in adults after cataract surgery remains uncertain. This study compared refractive outcomes obtained with a HH-ARM (Mediworks V100; Mediworks, Guangzhou, China) and a TB-ARM (Canon RK-F2; Canon Inc., Tokyo, Japan) to evaluate the clinical applicability of HH-ARM in this population.

Materials and methods: This prospective study included 150 eyes of 150 patients (aged 55–85 years) who underwent uncomplicated phacoemulsification with intraocular lens (IOL) implantation. At 1 month postoperatively, spherical value (SV), cylindrical …

Validation Of The Turkish Version Of The Assessment Of Systemic Sclerosis-Associated Raynaud’S Phenomenon (Asrap) ​, Duygu Temi̇z Karadağ, Şeyma Yilmaz, Betül Di̇kkanoğlu Demi̇rok, John D. Pauling, Ayten Yazici, Ayşe Çefle

Turkish Journal of Medical Sciences

No abstract provided.

An Examination Of The Experiences Of An African American Male Diver On A Power Four Swim Team: An Elite Interview, Steven N. Waller Ph.D., Tiffany M. Quash Ph.D.

International Journal of Aquatic Research and Education

Despite the incremental increase in the number of Black people who are learning to swim, the number of Black divers has not kept pace. In the NCAA Database, swimmers and divers were not segmented; thus, they all appear in the category of “swimming” by race and sex. When viewing the 2024 Division I NCAA Demographics Database, 89 (.02%) of 4307 student-athletes participating in swimming were Black women. For men, the data is equally dismal, revealing that 81 (.03%) of 2,608 student-athletes who were identified as swimmers were Black. The purpose of this research note is to examine the developmental experiences …

Efficacy Of Autologous Platelet-Rich Fibrin (Prf) In Promoting Soft Tissue Healing And Bone Regeneration Following Extraction In The Anterior Maxilla: A Digital And Radiological Study, Anthony El Rai, Abdallah Menhall, Joseph Zaarour, Robin Jalkh, Joseph Bassil

International Arab Journal of Dentistry

Objectives: The main objective of this study was to evaluate the effectiveness of PRF in promoting soft tissue healing and bone regeneration after extraction in the anterior maxillary region. A secondary objective was to correlate soft tissue change with underlying bone structure variation. Finally, the study also aimed to compare soft and hard tissue alteration based on different types of extracted teeth.

Methods: The sample included five adult patients requiring the extraction of at least two symmetrical teeth in the anterior maxilla, totaling fourteen teeth. Participants underwent CBCT scans and digital impressions before extraction. Concerned teeth were then …

Comparative Evaluation Of Heat-Treated Retreatment Files On Canal Transportation And Dentin Thickness In Endodontically Treated Teeth: An In Vitro Cbct Study, Monisha Bhate, Pradeep Solete, Aparna Mohan

International Arab Journal of Dentistry

Introduction: Non-surgical retreatment is a conservative approach for managing recurrent endodontic infections requiring efficient removal of obturating material while preserving dentin. Retreatment file systems,through their design and function,plays a vital role in ensuring effective cleaning and minimal structural compromise.

Methods: Forty-five extracted mandibular molars were decoronated and obturated at a standardized root length of 16 mm in both mesial canals. Samples were divided into three groups (n=15): Group 1 – SoliteRS3, Group 2 – Dentsply Protaper Universal Retreatment Files and Group 3 – Neoendo Retreatment Files. Pre- and postoperative CBCT scans were used to assess remaining dentin thickness, …

Full-Arch Rehabilitation Of Post-Mucormycosis Edentulous Maxilla Using Quad Zygomatic Implants: A Clinical Case Report, Akansha Bansod, Sweta Kale Pisulkar, Arushi Beri, Mony Behera, Pragya Manushree, Utkarsh Umre, Michael Subal Pramanik

International Arab Journal of Dentistry

Rehabilitating the maxilla in the patient who has had surgical resection for mucormycosis poses a distinctive set of anatomical, surgical, and prosthetic challenges. The extensive maxillary bone loss after aggressive debridement often makes traditional implant-supported prosthetic options impossible. In these circumstances, zygomatic implants have proven to be a predictable, graftless solution, especially in patients with extremely atrophic maxillae. Where the bone loss is severe, the quad zygoma procedure—two implants for each zygomatic arch—is possible to support full arch rehabilitation with a fixed prosthesis. This report presents the successful rehabilitation of oral function and appearance in a patient with post-mucormycosis edentulous …

Investigating Patient Non-Attendance To Healthcare Appointments In Türkiye: Data From A State Hospital And An Oral And Dental Health Center, Eyüp Sari, Ali̇ Ni̇yazi̇ Kurtcebe, Ci̇han Döğer, Recep Aydin

Turkish Journal of Medical Sciences

Background/aim: To determine the frequency and reasons for appointment nonattendance in a state hospital and a dental health center in a densely populated district of Türkiye, and to identify related factors to guide preventive measures.

Materials and methods: This retrospective cross-sectional study included patients who scheduled appointments at Ankara Etimesgut State Hospital and Etimesgut Oral and Dental Health Center through the Centralized Patient Appointment System (Merkezi Hekim Randevu Sistemi; MHRS) in February 2024. Nonattendees were contacted in March 2024 to determine reasons for nonattendance.

Results: A total of 30,552 appointments were analyzed (1978 dental, 28,574 hospital). The overall nonattendance rate …

Fear Of Covid-19 And Hygiene Behaviors: A Study Of Secondary School Students In İstanbul ​, Zozan Göksu, Hayri̇ye Kirkoyun Uysal, Mehmet Demi̇rci̇, Di̇lek Dülger, Seda Eki̇ci̇

Turkish Journal of Medical Sciences

Background/aim: This study investigates the relationship between fear of COVID-19, measured using the Fear of COVID-19 Scale (FCV-19S), and the hygiene behaviors of secondary school students, assessed with the Hygiene Behavior Scale (HBS).

Materials and methods: Included in this cross-sectional study were 206 secondary school students. The study data were analyzed using multivariate linear regression.

Results: No relationship was found between the fear of COVID-19 scale (FCV-19S) score of the student sample and the mean total HBS and subdimension values (p > 0.05). It was noted that positive hygiene behaviors decreased as the scale score increased. Students with retired mothers scored …

Impact Of Systemic Statins On Periodontal Health: A Retrospective Study In A Lebanese Population, Elsa Boustany, Georgio Saad, Wassim Al Manhal

International Arab Journal of Dentistry

Introduction: Statins, primarily used for cholesterol management, have shown potential in improving periodontal health due to their anti-inflammatory and bone-regenerative properties.

Methods: A retrospective study was conducted on 30 patients under statin medication. A control group of 30 non-statin users was selected using propensity score matching (PSM) to minimize bias. Data on pocket depth, attachment loss, and radiographic bone loss were collected at two time points: T0 and T1. Statistical analysis was performed using RStudio, with a significance threshold set at p < 0.05.

Results: The study revealed significant decrease in pocket depth (p = 0.0027), attachment loss (p …

Evaluation Of The Remineralizing Agents After Orthodontic Bracket Debonding: A Sem-Edx Investigation, Bassant Ashraf Badr, Medhat Elzainy, Noha Ibrahim, Hend El Messiry

International Arab Journal of Dentistry

Objectives: To compare the remineralizing efficacy of (Fluoride (Fl) Varnish, Nanohydroxyapatite (n-HAp) serum and NovaMin-containing toothpaste) on premolars subjected to orthodontic debonding and a pH-cycling model.

Methods: 60 human premolars were divided into six groups (n=10). Group IA, sound enamel, IB, orthodontically treated premolars, IC, orthodontically treated premolars subjected to demineralization cycles. Three experimental groups included orthodontically treated premolars subjected to demineralization cycles and treated with Fl varnish (IIA), n-HAp serum (IIB), and NovaMin toothpaste (IIC). Surface topography and mineral content were evaluated using SEM-EDX analysis, and data were statistically analyzed using ANOVA test and Tukey’s post-hoc test. …

Management Of A Periapical Cyst In An 8-Year-Old Patient With Challenging Etiology: A Case Report With Three-Year Follow-Up, Nancy Nochahrly, Claire El Hachem, Josephine El Balaa, Elie Khoury, Christelle Abdel Nour, Marlene Khoury

International Arab Journal of Dentistry

The success of pulp therapy in primary teeth depends on accurate diagnosis and effective treatment. Periapical inflammation due to bacterial infection or pulpal necrosis can result in granulation tissue and may activate epithelial rests of Malassez, leading to a periapical cyst. In large cysts, especially in children, marsupialization is preferred to preserve developing teeth and minimize damage to surrounding structures. This case report describes an 8-year-old presenting with spontaneous pain in the lower right jaw. Radiographic examination revealed a round welldefined radiolucency over 1 cm around tooth #84 with root canal treatment and #85 with pulpotomy, with dental bud displacement. …

Current Insights On Predicting Vestibular Diseases Using Machine Learning, Emre Söylemez, Muhammed Mustafa Şeker

Turkish Journal of Medical Sciences

The vestibular system is one of the three main systems responsible for maintaining balance and posture. Accurate vestibular inputs enable the perception of the head’s position and movement in space, and ensure coordination between head movements, eye movements, balance, and posture. Any dysfunction in the peripheral vestibular end organs, the vestibular nerve, or the central vestibular system may lead to vertigo, dizziness, and gait disturbances in individuals. Some syndromes that cause vertigo symptoms can be life threatening. Although peripheral vestibular pathologies are generally benign, they can reduce patients’ quality of life, cause falls, and hinder independence. Therefore, the diagnosis and …

Unveiling The Potential Of Marine Peptides In Leukemia: Mechanistic Insights And Future Horizon In Peptide Research, Salman Ahmed, Waqas Alam, Khalaf Alsharif, Michael Aschner, Esra Küpeli̇ Akkol, Mamdouh Allahyani, Hayaa Alhuthali, Luci̇ano Saso, Esra Gi̇zem Türkcanoğlu, Haroon Khan

Turkish Journal of Medical Sciences

Leukemia is a malignant disorder that affects the bone marrow and blood. It is frequently diagnosed in adults, with a higher incidence in males than females. Globally, it ranks as the 15th most widespread cancer and is the 11th leading cause of cancer-related fatalities. The intensity and severity of treatment have increased, leading to a rise in relapse rates, toxicity, and adverse health effects. Therefore, there is a critical need for new treatments. The antileukemic properties of natural compounds have been extensively studied. Aquatic organisms are a rich source of potential medicinal compounds. Anticancer peptides offer an ideal treatment approach …

A Randomized Controlled Prospective Study Comparing Surgical Outcomes Of Median Umbilical Ligament Lift-Up And Veress Needle Entry Techniques In Gynecologic Laparoscopic Surgery, Gazi̇ Güner, Ayşe Bacaksiz, Can Berk Karabudak, Fi̇gen Efe Çami̇li, Çi̇sem Ertok, Si̇nem Özşahi̇n Kiliç, Zeli̇ha Zeynep Satilmişoğlu, Can Tercan, Nazli Ayli̇n Vural

Turkish Journal of Medical Sciences

Background/aim: Laparoscopic surgery has become the preferred minimally invasive technique for both diagnostic and therapeutic procedures in gynecology. Although it is associated with lower overall complication rates compared to open surgery, most serious complications occur during the initial step of abdominal entry. Therefore, developing faster and safer entry methods is critical to improving surgical outcomes. This study aimed to compare the surgical results of the Median Umbilical Ligament Lift-Up (MULU) technique routinely used in our clinic with the commonly preferred Veress needle (VN) entry technique.

Materials and methods: This randomized, controlled, prospective study included 124 patients: 64 underwent abdominal entry …

Clinical Characteristics And Outcomes In Epstein-Barr Virus Positive Diffuse Large B-Cell Lymphoma: A Retrospective Multicenter Study, Ebru Kiliç Güneş, Hacer Berna Afacan Öztürk, Esra Ki̇ri̇kti̇r, Asena Di̇kyar, Bi̇lge Uğur, Ahmet Kürşad Güneş, Meltem Ayli

Turkish Journal of Medical Sciences

Background/aimEpstein-Barr virus-positive (EBV+) diffuse large B-cell lymphoma, not otherwise specified (DLBCL-NOS), represents a rare and aggressive subtype of B-cell lymphoma, officially classified as a distinct entity in the revised 4th edition of the World Health Organization (WHO) 2016 classification. This retrospective study aims to evaluate the prevalence, clinical characteristics, histopathological characteristics, and survival results of patients diagnosed with EBV+ DLBCL-NOS.Materials and methodsOur retrospective study included 92 newly diagnosed DLBCL patients treated at two centers between 2016 and 2024. EBV status was determined using in situ hybridization for EBER, with positivity defined as; ≥50% nuclear staining in tumor cells. ResultsAmong 92 …

Comparison Of Canada-United Kingdom-Australia (Canuka) Scores Of Patients With Gastrointestinal Bleeding Presenting To The Emergency Department With Other Gastrointestinal Bleeding Scores, Fatma Hancer Celi̇k, Necmi Baykan, Fatma Unlu, Mustafa Alpaslan, Ayse Sule Akan, Omer Salt, Ibrahim Toker, Nuh Mehmet Buyukberber

Turkish Journal of Medical Sciences

Background/aim: Acute gastrointestinal (GI) tract bleeding is a common and potentially life-threatening condition among patients presenting to emergency departments. In this study, we calculated AIMS65, Rockall, Glasgow-Blatchford Score (GBS), and Canada-United Kingdom-Australia (CANUKA) scores in patients with GI bleeding admitted to the emergency department and compared the sensitivity of these scoring systems in predicting the rates of admission to intensive care units and mortality. It is aimed to contribute to clinical practice and help determine an effective risk assessment tool in the management of patients with GI bleeding.

Materials and methods: The study was conducted with patients who were diagnosed …