Medicine and Health Sciences Commons^™

Efficacy Of Individualised Homoeopathic Medicines As An Adjunct To Conventional Iron And Folic-Acid Supplementation In Iron Deficiency Anaemia Among Reproductive-Aged Women: Single-Blind, Randomised, Placebo-Controlled Trial, Avidipta Hazra, Tanmay Sarkar, Debarsi Das, Rakesh Ghosh, Chandrani Ghosh

Indian Journal of Research in Homoeopathy

Background: Iron deficiency anaemia (IDA) is a major public health concern affecting women of reproductive age globally. If left untreated, it can cause various health issues including fatigue, shortness of breath, abnormal heart rhythms, chest pain, and complications during pregnancy. Objectives: To evaluate the efficacy of individualised homoeopathic medicines (IHMs) with iron and folic acid supplement (IFS) in treatment of iron deficiency among reproductive-aged women, in comparison with placebos with IFS. Methods: Single-blind, randomised, placebo-controlled clinical trial was conducted over total six months at the outpatient-department, of which participants received interventions and outcome assessments for three months. Reproductive women (15–49 …

Investigation Of Molecular Footprints In Ultra-High Diluted Homoeopathic Solutions Of Arnica Montana And Rhus Toxicodendron Through Combined Infrared And Impedance Spectroscopy, Sharbadeb Kundu, Usha Rani Dash, Chirasree Roychaudhuri, Aindrila Roy, Sanatan Chattopadhyay, Rathin Chakravarty, Debadatta Nayak, Subhash Kaushik, Amit Roy Chowdhury, Ananya Barui, Subhadip Chakraborty

Indian Journal of Research in Homoeopathy

Background: The study of ultra-high diluted (UHD) solutions is a compelling and controversial domain in modern science. Despite numerous investigations and hypotheses, there is a lack of rigorous, reproducible empirical evidence supporting the existence of molecular footprints beyond the Avogadro's limit. Objective: This study conducted a detailed investigation of the molecular and electrical properties, focusing on hydrogen bonding and impedance to understand the fundamental nature of UHD solutions. Materials and methods: Combined impedance and infrared spectroscopic investigations were performed to probe the structural behaviour of relevant water networks at the molecular level of UHD alcoholic extract of Arnica montana (AM) …

Mitochondria-Mediated Apoptotic Induction By Chionanthus Virginica Q: A Cytotoxic And Oxidative Stress-Driven Approach In Hepg2 Hepatocellular Carcinoma Cells, Arun R. Nair, Venkateshan Hariram, Vettrivel Arul

Indian Journal of Research in Homoeopathy

Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, with current therapeutic options limited by late-stage detection, recurrence, and toxicity. Alternative treatments derived from medicinal plants are gaining attention due to their potential anticancer properties. Chionanthus virginica, traditionally used for liver disorders, contains bioactive compounds with hepatoprotective and antioxidant effects. However, its anticancer potential remains largely unexplored. Objective: This study evaluates the antioxidant, cytotoxic, and apoptotic effects of Chionanthus virginica in mother tincture (Q) and potentised (12C) forms on HepG2 liver cancer cells to determine its efficacy as a natural anticancer agent. Materials and methods: HepG2 …

Non-Invasive Treatment For Indolent Chronic Venous Ulcer Using Individualised Homoeopathy: An Evidence-Based Case Series, Vinitha Edavattath Ramanan, Geethu Kp

Indian Journal of Research in Homoeopathy

Background: Venous ulcers account for 60–70% of all leg ulcers. They are irregular ulcers with sloping edges mainly seen above the medial malleolus associated with oedema, lipodermatosclerosis and hemosiderosis. Conventional medicine mentions chronic venous ulcers as a surgical disease. It usually results in further co-morbidities and reduces the patient's quality of life. Homoeopathic literature describes many medicines for the treatment of varicose ulcers. This case series demonstrates the role of homoeopathic treatment in the complete healing of venous ulcers non-invasively. Case Summary: This is a case series of five patients suffering from chronic venous ulcers resistant to conventional external medications …

Panic Disorder Treated With Individualised Homoeopathic Medicines: A Case Series, Hima Bindu Ponnam, Gr Kiranmayee Rompicherla

Indian Journal of Research in Homoeopathy

Introduction: Panic disorder is one category of generalised anxiety disorder that is commonly reported in a majority of the outpatient departments of primary care hospitals, especially in the COVID-19 post-pandemic era. Although its prevalence is lower compared to other anxiety disorders, panic disorder remains a serious concern, as it often leads to cardiorespiratory emergencies; therefore, prompt recognition and timely management are crucial. Since the first-line pharmacological interventions of modern medicine are expensive and associated with certain undesirable side effects, the homoeopathic system of medicine appears to be a safer and more economical alternative in such cases. Keeping this in view, …

Homoeopathy During One Hundred Years Of Lmhi (1925–2025) – Part 2: Historical Perspectives* (Continued From Part 1, Published In The Last Issue)1, Josef M. Schmidt

Indian Journal of Research in Homoeopathy

Taking Hahnemann in his entirety, as a paradigmatic example of a true homoeopath, as a sound basis for a proper understanding of Homoeopathy, the ``scientific-critical'' school of homoeopaths seems to miss one constitutive part of Homoeopathy: its spiritual embedment into a greater frame of thinking and feeling. In fact, the greatest successes of Homoeopathy, in terms of popularisation, institutionalisation and implementation into social and cultural practice, were achieved in countries and periods open towards spiritual dimensions. This was the case in North America at the end of the 19^th century, when James Tyler Kent propagated a Hahnemannian Homoeopathy inspired …

Screening Of Antiurolithiatic Activity Of Different Formulations Of Homoeopathic Medicines Using Calcium Oxalate Crystallisation Assay, Loganathan G, Satesh T

Indian Journal of Research in Homoeopathy

Background: Homoeopathic medicines such as Aerva lanata, Hydrangea arborescens, Berberis vulgaris, and Sarsaparilla are commonly used to treat kidney stones. Scientific research is needed to understand their effects on calcium oxalate crystallisation, a key factor in urolithiasis. Objective: The study evaluated the in vitro effects of Aerva Lanata, Hydrangea Arborescens, Berberis Vulgaris, and Sarsaparilla in Q, 6C, and 30C potencies on calcium oxalate crystallisation. It aimed to identify which potency had the strongest inhibitory effect compared to Ethanol (90%). Methods: Calcium oxalate (CaOx) crystals were synthesised by mixing calcium chloride and sodium oxalate, then cooled to 37°C to achieve a …

Capacity Building In Biorisk Management And Field Epidemiology: Proceedings Of A Biosafety And Outbreak Simulation Training Programme, Muralidharan Menon Arjun, Jain Vij Shruti, Panaparambil Azis Suhana, Gopinathan Pillai Sreekanth, Sudheesh N, Anup Jayaram, Prasad Varamballi, K. C. Muraleedharan, Sunil S. Ramteke, Subhash Kaushik, Chiranjay Mukhopadhyay

Indian Journal of Research in Homoeopathy

The Biosafety and Outbreak Simulation Training 2025, held from 6–10 October 2025 at Manipal, Karnataka, India, brought together thirty homoeopathic doctors from 14 states to strengthen national preparedness for infectious disease threats. Organised by the Manipal Institute of Virology (MIV) under Manipal Academy of Higher Education (MAHE) in collaboration with the Central Council for Research in Homoeopathy (CCRH), the workshop integrated theoretical sessions, hands-on training on sample transportation, and a comprehensive outbreak simulation exercise. Core modules spanned biorisk management, biosafety and biosecurity, biomedical waste management, incident response, epidemiological investigation, and sample transport in accordance with International Air Transport Association …

Research Highlights, Meenu Gupta, Sunaina Shanker

Indian Journal of Research in Homoeopathy

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Fundamental Research Principles In Homoeopathy: Bridging Empirical And Clinical Evidence, Himanshu Shekhar, Parth Aphale, Shashank Dokania

Indian Journal of Research in Homoeopathy

Letter to Editor

Homoeopathic Management Of Mania With Psychotic Symptoms-A Case Report, R. Bhuvaneswari, Sakthivel V

Indian Journal of Research in Homoeopathy

Introduction: Manic episode (ICD-F30.2) is typically characterised by distinct period of abnormally and persistently elevated, expansive, or irritable mood, along with abnormally and persistently increased goal-directed activity or energy, lasting at least 1 week and causing significant disruption in occupational and social functioning. The lifetime risk of experiencing manic episodes is approximately 0.8–1%. These episodes typically recur in three to four-month cycles. This case report aims to highlight significance of individualised homoeopathic treatment in managing mania with psychotic symptoms over a 41-month period without relapse, and without the use of conventional medication. Case Summary: An 18-year-old female was brought …

Holistic Approach Of Homoeopathy In Treatment Of Multimorbidity: A Case Report, Divya Verma, Nitin Kumar Saklani, Arun Kumar

Indian Journal of Research in Homoeopathy

Introduction: Multimorbidity, a rise in all ages, is a challenge for health care systems that are focused on single-disease management. Homoeopathy has shown competence in the management of chronic diseases, whether they occur as a single ailment or as multimorbidities. Case Summary: A 25-year-old female suffering from symptoms of PCOS, like irregular menses, secondary dysmenorrhea and secondary amenorrhea, along with chronic migraine visited the OPD. She also developed renal calculi during the previous homoeopathic treatment. Her condition improved through homoeopathic medicines Pulsatilla and Lycopodium. The case is reported according to HOM-CASE guidelines. The assessment of causal attribution of homoeopathic …

Acknowledgement To Our Reviewers (2025)

Indian Journal of Research in Homoeopathy

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Indian Standard For Alfalfa (Medicago Sativa L.), Kumar Vivekanand, Daisy Katarmal, Indra Gaurav Saxena, Binit Dwivedi, Divya Taneja, Shrishti Dixit, Raj Kumar Manchanda

Indian Journal of Research in Homoeopathy

Traditional systems of medicine remain integral to global healthcare, yet variability in herbal raw materials has long challenged their scientific validation and regulatory acceptance. Differences in environmental conditions, harvesting, processing and formulation techniques significantly influence the herb's phytochemical composition, potency, and therapeutic outcomes. Standardisation is therefore essential to ensure safety, efficacy, reproducibility, and regulatory credibility. In this context, the Bureau of Indian Standards (BIS) has developed Indian Standards for medicinal plants and homoeopathic preparations. This article presents an overview of IS 18978:2024, Alfalfa (Medicago sativa L.) for Use in Traditional Medicine—Specification, and IS 19135:2025, Alfalfa Hydro-alcoholic Extract for Use …

In Vitro And In Silico Evaluation Of Calcined Chicken Eggshell Powder As An Antibacterial Agent Against Staphylococcus Aureus, Hadi Kurniawan, Hariyanto Ih, Fajar Nugraha, Siti Nani Nurbaeti, Inarah Fajriaty, Ardi Kurniawan, Ridho Maulana Difa

Makara Journal of Science

Staphylococcus aureus is a major Gram-positive pathogen that is increasingly resistant to antibiotics, significantly contributing to antimicrobial resistance (AMR)-related deaths. Therefore, this study aimed to examine the antibacterial activity of calcined chicken eggshell powder (CCEP), a waste-derived material rich in calcium compounds. CCEP was prepared by calcining eggshell powder at 900 °C for 3 hours. Its antibacterial potential was evaluated using in vitro assays, including agar disc diffusion and broth microdilution, as well as in silico molecular docking against penicillin-binding protein 4 (PBP4, PDB ID: 3HUM). The in vitro results showed that a 20% (w/v) CCEP solution in glycerol produced …

Complications And Outcomes Of Orbital Fracture Repair In Oman, Saleh Al Ghailani, Abdulaziz Bakathir, Ahmed Al Ajmi, Shuhra Al Washahi, Tiamour Al Baloshi, Ahmed Al Hashmi

Sultan Qaboos University Medical Journal

Objective: This study aimed to investigate and analyse the complications and outcomes of orbital fracture repair in Oman. Methods: This multicentre retrospective study included all patients with orbital floor and/or medial wall fractures who underwent orbital reconstruction at four tertiary hospitals in Oman between January 2014 and December 2021. The data collected included demographics, fracture aetiology, surgical approach, reconstruction material, complications and repair outcomes. Results: A total of 41 patients were included in this study. Motor vehicle collisions (MVCs) were the most common cause of orbital fractures, accounting for (53.7%) of the patients. Isolated orbital fractures were encountered in …

Drug Procurement Methods And Challenges In Asian Low And Lower-Middle-Income Countries: A Systematic Review, Ferina Septiani Damanik, Anna Wahyuni Widayanti, Muhammad Qowiyul Amin

The Thai Journal of Pharmaceutical Sciences

Background: Pharmaceutical procurement plays a pivotal role in healthcare within Asian low and lower-middle-income countries (LLMICs), ensuring accessibility to essential, cost-effective, and high-quality medicines. Tailored approaches are imperative due to specific challenges inherent in these countries.
Objectives: This review examines several drug procurement systems in Asian countries with LLMICs while identifying and evaluating any potential challenges that might arise within the systems.
Materials and Methods: This review using the preferred reporting items for systematic reviews and meta-analyses guidelines and three search engines (PubMed, Science Direct, and Research Gate) employing Boolean search terms. The search focuses on drug procurement, medicine procurement, …

Efficacy And Safety Of Stem Cell-Based Interventions For Burn Wound Healing: A Systematic Review And Meta-Analysis Of Pre-Clinical And Early Clinical Evidence, Prayuth Poowaruttanawiwit, Patsanan Kulla, Naveeya Pakpoomkamonlert

The Thai Journal of Pharmaceutical Sciences

Background: Burn injuries remain a major therapeutic challenge, with conventional treatments often failing to achieve complete functional skin regeneration. Stem cell-based interventions, including mesenchymal stem cells (MSCs) and exosome derivatives, have demonstrated regenerative and immunomodulatory potential, yet their translation to clinical practice remains limited.
Objectives: To systematically evaluate the efficacy and safety of stem cell-based therapies for burn wound healing across pre-clinical and clinical studies.
Materials and Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines, four databases (PubMed, Embase, Scopus, and Cochrane) were searched through April 2025. Eligible studies included randomized controlled trials and controlled pre-clinical …

Characteristics Of Drug-Related Problems And The Impact Of Pharmacist Interventions On Hospital Drug Costs In The Medical Intensive Care Unit, Sirima Sitaruno, Wanrada Binyala, Pattama Phetsuk, Nisrin Ni-Ngoh, Worakarn Nukong, Asama Saiwaree, Nawaporn Assanangkornchai, Tanatape Wanishayakorn

The Thai Journal of Pharmaceutical Sciences

Background: Pharmaceutical care activities have been reported to enhance treatment outcomes and cost-effectiveness in critically ill patients. However, relevant and timely data on this topic are still lacking in Thailand.
Objectives: The objective of the study is to investigate the characteristics of drug-related problems (DRPs) identified during pharmaceutical care activities at the medical intensive care unit (MICU) of a tertiary care teaching hospital in Thailand. In addition, we aimed to quantify the impact of pharmacist interventions on hospital drug costs.
Materials and Methods: DRPs identified during pharmaceutical care activities over 3 years were reviewed and classified by the Pharmaceutical Care …

Optimization Of Solvent Extraction For Polyphenols And Antioxidant Activity From Zanthoxylum Acanthopodium Leaves Using Simplex Centroid Design, Waras Nurcholis, Indah Z. Septiawati, Roni Kartiman, Surya Diantina

The Thai Journal of Pharmaceutical Sciences

Background: Zanthoxylum acanthopodium DC., locally known as andaliman, is an indigenous spice from North Sumatra, Indonesia, recognized for its high antioxidant potential. Despite its bioactive richness, optimization of solvent extraction for phenolic and flavonoid compounds from its leaves remains underexplored, even though these compounds are valuable for food and pharmaceutical applications. The use of solvents such as acetone in analytical extraction contexts is acceptable; however, further purification steps would be required for applications in food and pharmaceutical products.
Objectives: The main objective of this study was to optimize solvent combinations – comprising water, ethanol, and acetone – to maximize the …

Pharmacognostic Analysis And Thin-Layer Chromatographic Study Of The Thai Antipyretic Herbal Formula Khiao-Bencha-Khan, Sirinapa Chaisri, Tassanee Paraput, Pravit Akarasereenont, Pinpat Tripatara

The Thai Journal of Pharmaceutical Sciences

Background: Khiao-bencha-khan formula (KBF) is an herbal formula recorded in Thai scriptures and used to treat fever, including exanthematous fever, and aphthous ulcers. It consists of Limnophila rugosa (Roth) Merr., Bacopa monnieri (L.) Wettst., Gossypium arboreum L., Pogostemon cablin (Blanco) Benth., Eupatorium japonicum L., and Justicia gendarussa Burm.f.
Objectives: This study aimed to identify the pharmacognostic and chemical profiles of the herbal components found in KBF.
Methods: All authentic plant materials were collected, and samples were prepared under Pharmaceutical Inspection Co-operation Scheme/good manufacturing practice guidelines. The materials were identified using macroscopic, microscopic, and thin-layer chromatography (TLC) methods.
Results: Microscopic analysis …

Design Of Experiments Based Reversed-Phase High-Performance Liquid Chromatography Method For Estimation Of Metformin And Glimepiride In Combined Dosage Forms, Neela Manish Bhatia, Rachana Patil, Harinath More, Rutuja Dattatray Chougale

The Thai Journal of Pharmaceutical Sciences

Background: The present study aimed to systematically develop and validate a robust, rapid, and stability-indicating reversed-phase high-performance liquid chromatography (RP-HPLC) method for the simultaneous estimation of metformin and glimepiride in fixeddose combination tablets. Method development was guided by a design of experiments (DoE) approach using the Box-Behnken design (BBD) to ensure optimal analytical performance.
Materials and Methods: Chromatographic separation was achieved on a Cosmosil C18 column using an optimized mobile phase of acetonitrile and water (80:20, v/v) adjusted to pH 3.5. The flow rate was 1 mL/min, and detection was performed at 221 nm. The BBD approach systematically evaluated the …

Development Of Aqueous Dispersions Of Zein–Inulin Nanoparticles: Influence Of Formulation Variables On Physical Properties, Wanarat Sayamol, Supakarn Chamni, Jittima Chatchawalsaisin

The Thai Journal of Pharmaceutical Sciences

Background: Zein-based nanoparticles exhibit considerable potential for pharmaceutical and food applications. Incorporating inulin, a prebiotic polysaccharide, can improve their functional performance. Owing to the distinct solubilities of zein and inulin in aqueous ethanol, zein– inulin nanoparticles can be prepared through precipitation using their respective anti-solvents.
Objectives: This study aimed to systematically develop zein–inulin nanoparticles using the antisolvent precipitation method, with a focus on investigating the effects of formulation variables on particle characteristics and dispersion properties.
Materials and Methods: Zein–inulin nanoparticles were prepared using an anti-solvent precipitation method. Zein and inulin were separately dissolved in aqueous ethanol and water, respectively. The …

Medicines Security And Bioprospecting: A Future Agenda For Pharmaceutical Research, Geoffrey A. Cordell

The Thai Journal of Pharmaceutical Sciences

Humanity is at an extraordinary moment in history, where our interwoven future in Gaia depends on showing reverence for the modulation of our resource limits after significant losses of biodiversity and encroaching environmental change, including disappearing glaciers, rising sea levels, and changing climates. Engaging with the interconnectedness of all life on Earth and integrating sustainability and optimization of the valuable, renewable resources for future generations are essential beginning actions. Fostering economic and resource sustainability deepens the focus for contemporary research priorities toward assuring access to biological agents needed by the consumer/patient. Based on the outcomes of the COP28/29/30 and COP15/16 …

Understanding The Coach Learning Environment In Formal, Field-Based Settings: A Self-Determination Theory Perspective, Jody L. Langdon, Shayla Snow

Journal of Coach Development

Grounded in self-determination theory (SDT), the purpose of this study was two-fold: 1) to evaluate the psychometric properties of SDT-related measures in a sample of coach learners, and 2) to examine the relationships between need satisfaction and frustration, coach motivation, and engagement in training sessions.. A total of 796 coaches participated in the study, completing surveys measuring basic psychological need satisfaction and frustration, coaching motivation, and engagement. Aside from confirming the validity and reliability of measures for use among coach learners, findings indicate that satisfaction of basic psychological needs positively correlated with intrinsic motivation and engagement, while frustration of these …

Best Integrated Writing Spring 2026 - Complete Edition, Wright State University School Of Humanities And Cultural Studies, Tracy Smith, Kristie Mckiernan

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University.

Bacteriophage Therapy For Antibiotic-Resistant Infections, Shiva Pariyar

Best Integrated Writing

Pariyar examines bacteriophage therapy as a promising alternative to antibiotics for treating multidrug-resistant infections, highlighting its targeted mechanism, ability to disrupt biofilms, and synergy with antibiotics. While challenges such as regulation, immune response, and limited clinical trials remain, the study argues that advances in biotechnology and global collaboration position phage therapy as a future cornerstone in combating antimicrobial resistance.

Exploring The Impact Of Education On Cardiovascular Health In Women: Sex Disparities, Symptom Recognition And Attribution, And Preventive Measures, Sydney Totten

Best Integrated Writing

Totten examines sex disparities in cardiovascular disease among women, emphasizing gaps in symptom recognition, treatment, and health education. Through a literature review and educational intervention, it demonstrates that targeted, nurse-led education can significantly improve women’s understanding of risk factors, symptoms, and disease management, ultimately supporting better health outcomes.

Influence Of Ceramic Thickness And Cad/Cam Ceramic Materials On The Fracture Resistance Of Indirect Restorations: An In Vitro Study, Lara El Hanach, Karim Corbani, Nabil Ghosn, Ryan Harouny, Cynthia Kassis

International Arab Journal of Dentistry

Objectives: This in-vitro study aimed to evaluate the impact of different CAD/CAM materials (IPS e.max® CAD and Cerasmart®) and thicknesses (0.7 mm, 1 mm, and 1.5 mm) on the fracture resistance of indirect overlay restorations.

Methods: Sixty-three human third molars were divided into 7 groups (n=9) based on material and thickness, including a control group of 9 sound teeth. Only 54 specimens were prepared using a thin-section cutting machine, scanned, and their scans were used to fabricate overlays from different materials and thicknesses. After adhesive cementation, the overlays underwent thermal cyclic loading (5,000 cycles between 5°C and 55°C). A universal …

Aquifer Characteristics And Groundwater Flow Modeling For Sustainable Water Resources Development And Planning Using Modflow Software In India, Ravi Sharma

AUIQ Complementary Biological System

MODFLOW is one of the most commonly used numerical models for simulating groundwater flow. Its structured data design and compatibility with GIS tools make it suitable for groundwater assessment and planning. Groundwater forms an important part of the hydrological cycle and occurs within the pore spaces of sedimentary rocks or within fractures in hard rock terrains. Although its distribution beneath the surface is not always uniform or predictable, it is still considered one of the cleanest, most accessible, and quickly available freshwater sources. Numerical groundwater models help convert complex subsurface processes into simplified relationships that describe flow behavior. Even though …