Medicine and Health Sciences Commons^™

Comparison Of Clinical Outcome Of Mushroom Poisonings With And Without Specific Treatment: A 5-Year Retrospective Analysis, Kamil Deveci, Necmi Baykan, Baycan Kus, Fatma Ünlü, Ömer Salt, Serhat Koyuncu

Saudi Medical Journal

Objectives: To determine the demographic and clinical characteristics, potential specific antidote treatments, clinical outcomes, and organ failure (morbidity) rates of patients with mushroom poisoning admitted to our center. Methods: We included 425 patients admitted to the emergency department of Kayseri City Hospital complaining of mushroom poisoning, between May 2018 and December 2023, who met the study criteria. Results: The median age of the 425 patients admitted was 51 years (34–63); 49.5% were female (n = 211), and 75% (n = 319) were admitted by ambulance. According to the Poisoning Severity Score, 70.3% (n = 299) of cases were mild, 21.9% …

Ethnic Background As A Determinant Of Thyroid Cancer Risk: A Decade-Long National Cohort Study Reveals Divergent Epidemics In Saudi Arabia, Nizar A. Khamjan

Saudi Medical Journal

Objectives: To analyze and compare temporal trends, demographic characteristics, and stage at diagnosis for thyroid cancer (TC) between Saudi and non-Saudi populations in order to identify potential population-specific etiological drivers. Methods: We conducted a national retrospective cohort study of TC cases in Saudi Arabia from 2013–2022. To assess population-level trends, we computed age-standardized incidence rates (ASIRs) and multivariable Poisson regression alongside piecewise regression models for comparative analysis. Results: Among 14,159 total cases, TC incidence increased disproportionately in Saudi nationals, rising from 884 to 1,677 (90%), significantly outpacing the 184 to 275 (49%) increase observed in non-Saudis. The incidence rate ratio …

Comparison Of The Predictive Value Of Crp/Albumin, Crp/Prealbumin, And The Clinical Frailty Scale For Mortality In Geriatric Intensive Care Patients, Natali T. Aksoy, Bülent B. Güven, Sümeyya M. Soyalan, Dilek Metin Yamaç, Tuna Ertürk, Süheyla Abitağaoğlu

Saudi Medical Journal

Objectives: To evaluate the relationship between C-reactive protein (CRP)/prealbumin and CRP/albumin ratios, Clinical Frailty Scale (CFS) scores, and short-term (first 3 days) and long-term (28 days) mortality in geriatric patients hospitalized in the intensive care unit. Methods: After obtaining ethical approval and informed consent, 213 patients aged 65 years and older were included. Patients discharged within 24 hours, those discharged and readmitted during the study period, those receiving routine albumin replacement, and patients with cirrhosis or undergoing chronic dialysis were excluded. Demographic characteristics, admission diagnoses, chronic comorbidities, frailty scores at admission, and laboratory values, including albumin, prealbumin, and CRP …

Tumor-Associated Neutrophils In Advanced Non-Small Cell Lung Cancer Patients Predicted By Clinicopathologic Characteristics And Peripheral Blood Markers, Weiwei Hong, Xie Xiong, Chen Fang, Chuanhong Luo, Xiaoying Qian, Xinyuan Yao, Xin Ye, Biao Yu, Bingbiao Zhou, Dengying Chen, Chengsi Shu, Yong Wang, Yong Li

Saudi Medical Journal

Objectives: The process of analyzing tumor-associated neutrophils (TANs) types is complex. This study explored the relationships among clinicopathological characteristics, peripheral blood markers, and TANs. Methods: Clinical information was retrospective gathered for 115 patients in our hospital from May 2019 to May 2021, and multiplex immunofluorescence staining was utilized to access the expression of TANs and analyze the potential relationship between TANs and clinicopathological features or peripheral blood markers. Results: Among the 115 patients, the proportion of female patients within the neutrophils (N1)-low group was notably greater compared to the N1-high group (87.5% vs. 12.5%, p = 0.022). In nonsmoking patients, …

Clinical Role Of Hematologic Inflammatory Markers In The Diagnosis Of Missed Abortion, Mustafa Bakırcı, Çağlayan Ateş, Ethem S. Yalvaç

Saudi Medical Journal

Objectives: To evaluate the diagnostic value of hematological and biochemical inflammatory markers in distinguishing missed abortions from healthy pregnancies during the first trimester. Methods: This retrospective case-control study was conducted between May 2022 and May 2024, included 61 women diagnosed with missed abortion by ultrasound and 100 healthy pregnant women who acted as controls. The following inflammatory markers were calculated from routine blood and biochemistry results: neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), monocyte-lymphocyte ratio (MLR), lymphocyte-monocyte ratio (LMR), systemic immune-inflammation index (SII) and C-reactive protein-albumin ratio (CAR). Intergroup comparisons and receiver operating characteristic (ROC) curve analyses were performed. Results: The …

Concurrent Appendectomy In Patients Undergoing Surgery For Gynecological Malignancies: A Retrospective Analysis From A Tertiary Referral Center, Gazi Güner, Can Tercan, Emrah Dağdeviren, Ali Selçuk Yeniocak, Ceylin Elbistanli, Sure Nur Erdoğmuş, Ayşe Hazirbulan, Yiğit Mert Bayrak, Neçirvan Çağdaş Çaltek, Gözde Şahin, Ergun Tercan, Figen Efe Çamili, Nazlıaylin Vural, Hüseyin Karatay, Saniye Merve Gül Kara, İlkbal Temel Yüksel

Saudi Medical Journal

Objectives: To evaluate appendectomy specimen findings and their association with tumor type and stage. Concurrent appendectomy is frequently performed during gynecologic oncology surgery to prevent postoperative appendicitis and detect occult pathology, yet its value remains debated. Methods: In this study, we reviewed the medical records of 300 women who underwent gynecologic oncologic surgery accompanied by appendectomy at Başakşehir Çam and Sakura City Hospital (Istanbul, Türkiye) over the period from July 2020 to April 2025. Clinical, surgical, andhistopathologic data were collected. Appendiceal pathologies were categorized as reactive hyperplasia, chronic inflammation, benign neoplasms, metastatic tumors, or primary. Statistical analyses included chi-square, t-test, …

Reliability And Validity Of The Arabic Version Of The Nose-Perf Scale, Rayan M. Alfallaj, Abdullah I. Binghaith, Mohammed Y. Alyoussef, Ahmed S. Alsaleh, Saad A. Alsaleh, Abdulaziz A. Alqahtani, Ahmad S. Alroqi

Saudi Medical Journal

Objectives: To assess the psychometric validity of the Arabic adaptation of the nasal obstruction symptom evaluation–perforation (NOSE-Perf) scale. To assess how reliable and valid the Arabic adaptation of the NOSE-Perf questionnaire is. Patients with septal perforations, particularly Arabic speakers, lack validated self-assessment tools for subjective symptom evaluation. Methods: Conducted between May 2024 and June 2025, the study included 100 participants—20 patients with septal perforation and 80 controls. Participants filled out a questionnaire consisting of demographic data as well as the Arabic forms of the Sino-Nasal Outcome Test-22 (SNOT-22), NOSE, and NOSE-Perf scales. Cronbach's alpha was applied to determine internal consistency, …

A Multi-Centre Study: Quantitative Evaluation Of Radiation Dose For Adults Head Computed Tomography, Abdulaziz A. Qurashi, Shrooq T. Aldahery

Saudi Medical Journal

Objectives: To determine regional radiation dose in adults head computed tomography (CT) examinations in Jeddah by assessing the volume computed tomography dose index (CTDI_vol) and dose length product (DLP) values. Methods: A retrospective study was conducted from February to April 2025 across 10 CT scanners from 5 governmental hospitals in Jeddah. Data for 20 head CT examinations per scanner were collected. Dose metrics including CTDI_vol and DLP (mGy·cm), were extracted from digital imaging and communications in medicine (DICOM) images. Mean values per scanner and the 75^th percentile were calculated across centres to identify the regional DRL. …

The Role Of The Delta Neutrophil Index In Determining The Severity Of Intrahepatic Cholestasis Of Pregnancy, Selçuk Atalay, Melike Çaltekin, Nihal Çallıoğlu, Fırat Ersan, Verda Alpay, Yasin Anasız, Ipek Geyikoğlu

Saudi Medical Journal

Objective: This study aimed to investigate the clinical utility of the delta neutrophil index (DNI) in distinguishing patients with intrahepatic cholestasis of pregnancy (ICP) from healthy pregnant women, and to assess its potential role in evaluating disease severity. Methods: This retrospective analysis included data from 249 pregnant women. Among them, 131 were identified with ICP, based on clinical symptoms and total bile acid levels ≥ 10 μ mol/L. The remaining 118 participants served as healthy controls. The ICP cases were categorized into mild (TBA 10–39 μ mol/L; n = 90) and severe (TBA ≥ 40 μ mol/L; n = 41) …

Integrative Approaches To Gut Microbiota: Biomarkers, Dysbiosis, And Therapeutic Potential, Zeyad M. Alharbi

Saudi Medical Journal

The human gut contains bacteria, viruses, and archaea that influence health depending on age, diet, and location. An individual harbours about 150 bacterial species. An imbalance of these microorganisms, known as dysbiosis, can negatively impact health. Commensal bacteria maintain microbial homeostasis by building short chain fatty acids. The 2-way communication channel that connects the gut and the brain is referred to as the gut-brain axis. Dysbiosis of the gut leads to some autoimmune diseases. A decline of beneficial bacteria causes the progression of rheumatoid arthritis. Gut dysbiosis increases intestinal permeability, allowing toxins and cytokines to enter the bloodstream and damage …

Emerging Nanotherapy Applications In Cancer Treatment: A Comprehensive Review, Waleed H. Mahallawi

Saudi Medical Journal

This comprehensive review synthesizes recent advances in cancer nanotherapy, focusing on 6 emerging categories: immunomodulation, gene/RNA delivery, theranostics, radiosensitization, biomimetic carriers, and artificial intelligence (AI)-guided formulations. These innovative platforms demonstrate transformative potential by overcoming key limitations of conventional cancer treatments. Immunomodulatory nanoparticles reprogram tumor microenvironments and convert immunologically ``cold'' tumors to ``hot'' responsive states. Gene delivery systems enable precise editing with >50% efficiency, while theranostic platforms integrate real-time imaging with targeted therapy. Radiosensitizers amplify local radiation dose by twofold, and biomimetic carriers achieve prolonged circulation through immune evasion. An AI-driven approaches optimize personalized formulations based on patient-specific biomarkers. Clinical evidence …

Treatment Of Odontogenic Sinusitis With Oroantral Communication And Fistula: A Systematic Review And Meta-Analysis, Rana R. Alharbi, Omar F. Alnajar, Reham E. Almahdi, Salman A. Alrougi, Remas A. Alshehri, Ruyuf A. Alotaibi, Shahad S. Alharbi, Manal A Eltahir, Yahya A. Fageeh

Saudi Medical Journal

Objective: To assess the available data regarding medicinal, surgical, and combination therapy approaches for odontogenic sinusitis linked to OAC and OAF. Oroantral communication (OAC), an atypical connection between the oral cavity and maxillary sinus, commonly arises following upper jaw procedures, trauma, or infection. Chronic odontogenic maxillary sinusitis may result from OAC developing into an oroantral fistula (OAF) if treatment is not received. Recurrent infections and functional difficulties can be avoided by managing these illnesses effectively. Methods: A systematic search was conducted in National Library of Medicine's (PubMed [MEDLINE]) and Google Scholar for studies published between 2000 and 2024. A total …

Mental Health In Relation To Parental Absence: A Systematic Review, Mohammed Barry, Abdulaziz Alyahyawi, Heba Jafar Sabbagh

Saudi Medical Journal

Objective: To evaluate the literature based on the relationship between orphaned children and mental health, compared to non-orphaned children. Mental well-being of orphaned children is a profound intricate topic that connects with broader concerns of childcare. This systematic review aims to evaluate the literature regarding the relationship between mental health and parental absence. Methods: We conducted a systematic search of PubMed, MEDLINE, and Science Direct in October 2025, with 1017 screened studies. Six studies met the inclusion criteria. Independent reviewers performed quality assessments using the Newcastle-Ottawa scale (NOS). Subsequently, a meta-analysis was performed when possible. Results: Findings indicate that orphaned …

Hypoxemia Following Surgical Repair Of Partial Anomalous Pulmonary Venous Connection With Interrupted Inferior Vena Cava:Insights From Cardiac Ct, Mahmoud F Elshahat, Ahmed Goha, Naif S. Alghasab, Ahmad Alomrani

Journal of the Saudi Heart Association

Preoperative understanding of complex congenital heart disease is crucial for proper management. Surgical direction of partial anomalous pulmonary venous drainage and atrial septal defect closure when combined by the rare azygos continuation of interrupted inferior vena cava (IVC) may be associated with anomalous systemic to pulmonary venous connection, causing right-to-left shunt. We report a 44-year-old male with a history of congenital heart disease repaired in early childhood. Diagnostic imaging revealed an interrupted IVC with azygos continuation draining into the right upper pulmonary vein to the left atrium. CT play an essential role in recognition of venous anomalies with unexplained cyanosis.

An Ethics Of Listening: The Rupture Of Delusion And The Offer Of A New Freedom, Bret Fimiani

Middle Voices

This paper will focus on the topic of listening as an ‘analytic act’ by the analyst (but also by the analysand) and its relation to ethics and the position of the analyst in the field of psychosis. Is the analyst listening for something in particular? The prospect of listening for something supposes that the analyst holds a specific idea of what distinguishes the ‘structure of the address’ in psychosis (versus neurosis). Typically, we say that the analyst is listening for the unconscious, or for the ‘subject’ (of the unconscious). As we are trying to find our bearings in the field …

Creating An Unconscious: Toward A New Ethic Of Residential Treatment, Daniel Garcia

Middle Voices

What is currently nominated “residential treatment” for serious mental illness (SMI) has a long and varied history. From its earliest version as houses for the unproductive, to confinement of and with the unruly and criminally dangerous, to asylumdom, residential treatment has always sought to protect society from those it perceives as actively trying to revoke it. Consequently, the remedies prescribed in defense of civilization have also ranged from the gruesome to the utopian and the seat of responsibility for maintenance of the social order has vacillated between the family and the church, the local community and the state, the psychiatric …

What Are Elementary Phenomena? An Introduction To A Lacanian Conceptualization, Derek Hook Ph.D.

Middle Voices

What do Lacanians mean when they refer to the notion of elementary phenomena? This idea, crucial to Lacan’s (1993) theorizations of psychosis in Seminar III, refers back to the psychiatric conceptualizations of the late 19th and early 20th century. However, even while citing the influence of others when utilizing the concept, Lacan—characteristically enough— described the concept in his own distinctively psychoanalytic way. The term is particularly important to Lacan in terms of how he thinks about the development of delusions and related psychotic symptoms in relation to the initial onset of psychosis. In this short paper, I aim simply to …

Working With Schizophrenia: Adaptive Work & The Threat Of Despair, Pavan S. Brar

Middle Voices

Commentary

The Wager Of Speech, And The Maneuver Of The Dream In The Clinic Of Psychosis, Christopher Meyer

Middle Voices

Psychoanalysis, especially in the clinic of psychosis and extreme states, requires a wager on the part of the analyst. This wager welcomes the speech of the analysand regarding a censored unconscious. In the clinic of psychosis, the analyst’s reference to the dream in the establishment of the frame of the treatment is a maneuver that creates a working space that reveals the subjective history of the analysand. This history concerns key moments of trauma in which the speaking being found themselves without resort or resource to speech or language to represent their experience. The discourse of the delusion arises in …

Psycho-Pathology And Links Between Neurosis And Psychosis, B. Mason Judy, John Dall'aglio

Middle Voices

Commentary

The Secretary Of Alienation: Metaphor And Metapsychology, Anna Kreienberg

Middle Voices

Commentary

An Interview With Stijn Vanheule, Phd Following His Talk: “The Clinic Of Psychoanalysis In Times Of Capitalism”, Stijn Vanheule

Middle Voices

An interview with Stijn Vanheule

Thinking With The Feet In The Clinic Of Psychosis, Jed Wilson

Middle Voices

In his later work, Lacan makes occasional reference to the idea of “thinking with the feet.” An equivocal formulation, it first seems to suggest that thought and language can be regarded as physical processes—not occurring in some homunculan disembodied brain or mind, but in the real of the body. Equally, it can call to mind the idea of thinking “on” one’s feet, in the manner of adaptive improvisation. Going further, could we not also say that it points to the possibility of setting something in motion (as in walking, dancing, going somewhere—all the things we do with the feet) as …

Beyond Symptoms: A Narrative Counseling Interpretation Of First-Year Student Anxiety In Indonesian Higher Education, Azizah Abdullah, Rizky Andana Pohan, Ramtia Darma Putri, Triyono Triyono, Marimbun Marimbun, Rahmi Dwi Febriani

Buletin Konseling Inovatif

The transition to higher education is a critical period in which first-year students face new academic demands, financial pressures, social adjustment challenges, and uncertainty about the future. However, limited research has examined how freshmen make sense of and narrate their anxiety, particularly in the Indonesian context. This study aimed to explore the main domains of anxiety among first-semester students in Indonesian public universities and to interpret these experiences through a narrative counseling lens. The study employed a qualitative online survey design with an interpretivist orientation. Data were collected from 199 first-semester students through open-ended questions addressing anxiety-provoking situations, sources of …

Governing Addiction: An Anthropological Comparison Of Care In The United States And The Netherlands, Kiren K. Bagga

Bates College Journal of Political Studies

This article examines addiction care as a form of moral governance through a comparative anthropological analysis of the United States and the Netherlands. Drawing on a Foucauldian theory of biopolitics alongside this study argues that approaches to addiction treatment reveal how states differentially value life, citizenship, and vulnerability. Joan Tronto's relational definition of ethical care is used to move beyond a solely moral context, towards an ethical understanding of both caretakers and those who require care. In the United States, addiction policy has historically functioned as a punitive and moralizing project, shaped by racialized drug criminalization, neoliberal ideals of individual …

Smoking Habits And Attitudes Of Dental, Nursing And Pharmacy Students, Daniel M. Laskin Dds, Ms, Caroline K. Carrico

Virginia Dental Journal

No abstract provided.

Interactive Associations Between Physical Activity And Sleep Architecture On Cognition In Community-Dwelling Older Black Adults, Joshua L. Gills, Anhiti Dharmapuri, Rachel Mccray, Shreshtha Shah, Anthony Q. Briggs, Purbanka Pahari, Dominique Tanner, Mark A. Bernard, Elena Valkanova, Korey Kam, Ankit Parekh, Lisa L. Barnes, Gbenga Ogedegbe, Omonigho M. Bubu

International Journal of Exercise Science: Conference Proceedings

Growing evidence suggests an interactive relationship between physical activity (PA) and sleep in shaping cognitive performance. Enhanced sleep features, like greater K-complex density and slow-wave activity, may reflect mechanisms through which PA and restorative sleep improve cognitive function. PURPOSE: To examine how PA and sleep architecture interact to influence cognition in older Black adults. METHODS: A cross-sectional study of 51 participants (mean age: 63.1 ± 15.8 years) from NYU’s Aging Research In Sleep Equity and Dementia Prevention Program. Participants underwent neuropsychological testing, polysomnography, clinical evaluation, and seven days of actigraphy to assess PA and sedentary behavior. Cognitive tasks measured processing …

Use Of Resistive Exercise Snacks To Improve Upper Body Fitness In Undergraduate And Graduate Students, Zachary Abouelkawaam, Kevin Vaughan, Alexander Rothstein, Abdelmohsen Mossolem, Jean-Paul Dodier, Carlos Africa, Freddie Leong, John Handrakis

International Journal of Exercise Science: Conference Proceedings

Graduate/undergraduate students lack time for consistent physical activity, leading to declines in fitness. Exercise snacks (ExSnck), short bouts of submaximal exercise performed throughout the day, may offer a solution. PURPOSE: To evaluate the effects of a 6-week upper body ExSnck program on endurance, strength, power, and enjoyment compared to a 1-set maximal exercise (MaxEx) protocol and a control group. METHODS: 43 participants were randomly assigned to ExSnck (n=15), MaxEx (n=16), or Control (n=12) groups. The ExSnck group performed 33% of their maximal push-ups and plank time for 3 sessions/day (sessions ≥2hrs apart). The MaxEx group performed the same …

Association Between Coaching Behavior Styles And Athlete Well-Being: A Systematic Review, Matthew Benavides, Olivia Evola, Devjja V. Joshi, Arpita M. Bedarkar, Amerigo Rossi

International Journal of Exercise Science: Conference Proceedings

Coaching behavior plays a critical role in shaping athlete outcomes, including motivation, performance, satisfaction, and burnout. PURPOSE: Evaluates how different coaching styles are associated with athlete well-being and the psychological mechanisms involved. METHODS: A detailed search of ProQuest, Gale and EBSCO databases was done. Five peer-reviewed studies that met the inclusion criteria of college student athletes competing in NCAA or NAIA in the US or Canada and studies involving the coaching styles of either autocratic, democratic, transformational, congruent leadership or intrinsic motivation were systematically reviewed. 1,900 athletes were evaluated in the included studies of relationships between coaching behaviors and student …

Pediatric Cardiac Imaging With Second- And Third-Generation Dual Source Ct Scanners: Radiation Dose, And Diagnostic Accuracy In Comparison With Echocardiography And Mri—A Systematic Review And Meta-Analysis, Lamia Ghazi Jamjoom, Razan Kamal Daghistani

Journal of the Saudi Heart Association

Objectives: The purpose of this study was to evaluate the diagnostic accuracy, imaging speed, radiation dose, and clinical utility of second- and third-generation dual source computed tomography scanners, in comparison with echocardiography and magnetic resonance imaging in diagnosing congenital heart disease in paediatric patients.

Material and Methods: A systematic literature search was conducted in PubMed, Embase, Scopus, and the Cochrane Central Register of Controlled Trials from 1 January 2006 to 30 April 2025.  Eligible studies included pediatric populations undergoing cardiac imaging with modern computed tomography scanners and compared outcomes against echocardiography or magnetic resonance imaging. Study selection followed PRISMA guidelines. …