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Articles 1 - 30 of 215
Full-Text Articles in Medicine and Health Sciences
Effects Of Etomidate On Blood Cortisol, Insulin, And Glucose Levels And Ponv Rates In Smokers, Cevdet Sümer, Ömer Lütfi̇ Erhan, Ayşe Beli̇n Özer, Fuat Yildiz
Effects Of Etomidate On Blood Cortisol, Insulin, And Glucose Levels And Ponv Rates In Smokers, Cevdet Sümer, Ömer Lütfi̇ Erhan, Ayşe Beli̇n Özer, Fuat Yildiz
Turkish Journal of Medical Sciences
To observe differences in the effects of etomidate, used for anesthesia induction, on surgery-induced endocrine response and postoperative nausea and vomiting (PONV) among nonsmokers and smokers. Materials and methods: Eighty adult patients with ASA I-II risk status were randomly divided into 2 groups: smokers (Group I, n = 40) and nonsmokers (Group II, n = 40). Patients were then further divided into subgroups according to the drug used for anesthesia induction, either propofol (Group IP and Group IIP) or etomidate (Group IE and Group IIE). Blood cortisol, insulin, glucose, and white blood cell (WBC) levels were measured and PONV scores …
Evaluation Of The Antibacterial Activity Of Zataria Multiflora Boiss., Rhus Coriaria L. (Sumac), Mentha Piperita L., And Ocimum Basilicum L. Extracts On Brucella Strains Isolated From Brucellosis Patients, Yousef Motaharinia, Mohammad Ali Rezaee, Mohammad Saleh Hazhir, Farid Zandi, Reza Shapouri, Mohammad Saied Hakhamaneshi, Ahmad Rashidi, Mohammad Reza Rahmani
Evaluation Of The Antibacterial Activity Of Zataria Multiflora Boiss., Rhus Coriaria L. (Sumac), Mentha Piperita L., And Ocimum Basilicum L. Extracts On Brucella Strains Isolated From Brucellosis Patients, Yousef Motaharinia, Mohammad Ali Rezaee, Mohammad Saleh Hazhir, Farid Zandi, Reza Shapouri, Mohammad Saied Hakhamaneshi, Ahmad Rashidi, Mohammad Reza Rahmani
Turkish Journal of Medical Sciences
Since brucellosis has been called a chronic illness and treatment of patients infected with this bacterium has not been successful, the present study aim ed to evaluate the effects of several medicinal plant extracts on clinical Brucella strains. Materials and methods: First, Brucella strains were isolated from brucellosis patients. Then an antibiotic resistance assay was performed for these strains, while the antibacterial activity of the above-mentioned extracts was evaluated. Results: After performing accurate evaluations, the obtained results showed that all of the isolated Brucella strains were sensitive to tetracycline, doxycycline, and gentamicin, and the rates of antibiotic resistance to rifampin …
Endovascular Treatment Of Abdominal Aortic Aneurysms With Endologix® Stent Graft: Single-Site Experiences And Short-Term Follow-Up Outcomes, Mustafa Kayan, Turhan Yavuz, Mustafa Etli̇, Şeyma Benzi̇n, Seda İbi̇şoğlu, Esma Di̇lek Üstün, Mert Köroğlu, Ergün Ceylan, Ulaş Sağlam
Endovascular Treatment Of Abdominal Aortic Aneurysms With Endologix® Stent Graft: Single-Site Experiences And Short-Term Follow-Up Outcomes, Mustafa Kayan, Turhan Yavuz, Mustafa Etli̇, Şeyma Benzi̇n, Seda İbi̇şoğlu, Esma Di̇lek Üstün, Mert Köroğlu, Ergün Ceylan, Ulaş Sağlam
Turkish Journal of Medical Sciences
The aim of this study was to investigate the short-term results of endovascular repair of abdominal aortic aneurysms with the Endologix IntuiTrak Powerlink XL® (Endologix) stent graft and to share our clinical experiences in our center. Materials and methods: Endovascular stent graft treatment was applied in 16 cases with infrarenal abdominal aortic aneurysm (13 men and 3 women; mean age: 70.2 years) in 2009 and 2010. Before treatment, all of the patients were examined with 128-slice computed tomography (CT) angiography for the assessment of abdominal aortic aneurysms. The Endologix stent graft (bifurcated system) was used for all of the patients. …
Dysregulation Of Nitric Oxide Synthase Activity And Bcl-2 And Caspase-3 Gene Expressions In Renal Tissue Of Streptozotocin-Induced Diabetic Rats, Hüseyi̇n Aktuğ, Vi̇ldan Bozok Çeti̇ntaş, Buket Kosova, Fati̇h Oltulu, Şi̇ri̇n Bakti Demi̇ray, Türker Çavuşoğlu, Saadet Özen Akarca, Altuğ Yavaşoğlu
Dysregulation Of Nitric Oxide Synthase Activity And Bcl-2 And Caspase-3 Gene Expressions In Renal Tissue Of Streptozotocin-Induced Diabetic Rats, Hüseyi̇n Aktuğ, Vi̇ldan Bozok Çeti̇ntaş, Buket Kosova, Fati̇h Oltulu, Şi̇ri̇n Bakti Demi̇ray, Türker Çavuşoğlu, Saadet Özen Akarca, Altuğ Yavaşoğlu
Turkish Journal of Medical Sciences
To evaluate the effects of diabetes on nitric oxide synthase (NOS) activity and on gene expressions of B-cell lymphoma protein 2 (Bcl-2) and caspase-3 in the renal tissues of streptozotocin (STZ)-induced rats. Materials and methods: Twenty rats were analyzed in 2 equally distributed groups of healthy controls and STZ-induced diabetic rats. Rats with blood glucose levels of >=250 mg/dL were considered diabetic. Renal tissue sections were analyzed histomorphologically and immunohistochemically. Gene expressions of caspase-3 and Bcl-2 were evaluated by real-time quantitative polymerase chain reaction. Results: Bcl-2 expression significantly decreased in the diabetic group, both at the gene and protein level. …
Is The Six-Minute Walk Test Correlated With Disease Control And Quality Of Life In Children With Asthma?, Hasan Yüksel, Özge Yilmaz, Bülent Gökşen, Senem Üstün, Ayhan Söğüt
Is The Six-Minute Walk Test Correlated With Disease Control And Quality Of Life In Children With Asthma?, Hasan Yüksel, Özge Yilmaz, Bülent Gökşen, Senem Üstün, Ayhan Söğüt
Turkish Journal of Medical Sciences
To evaluate the changes in a 6-min walk test (6MWT) and quality of life (QoL) before and after asthma control is achieved in children. A 6MWT is used in the determination of disease severity in many chronic childhood diseases. Materials and methods: Thirty-six asthmatic children, aged 6 to 15 years, were enrolled before asthma control was achieved. Disease severity parameters during the previous 3 months were recorded. All of the children completed an asthma control questionnaire (ACQ) and received a symptom score; a 6MWT was performed during enrollment and 1 month later, when asthma control was achieved. Results: The initial …
The Effects Of Stress Urinary Incontinence On The Quality Of Life Of Turkish Women In The Reproductive Age Group, Elçi̇n Balci, Özlem Gürlevi̇k, İskender Gün, Osman Günay
The Effects Of Stress Urinary Incontinence On The Quality Of Life Of Turkish Women In The Reproductive Age Group, Elçi̇n Balci, Özlem Gürlevi̇k, İskender Gün, Osman Günay
Turkish Journal of Medical Sciences
This study was performed in order to evaluate the effect of urinary incontinence (UI) on the quality of life of women in the reproductive age group. Materials and methods: Included in the study were 150 women with UI [stress urinary incontinence (SUI) or mixed urinary incontinence (MUI)] and 150 healthy women, ranging in age between 15 and 49 years. Short Form 36 (SF-36) and the Urogenital Distress Inventory (UDI-6) were filled in by the women in both groups and the Incontinence Impact Questionnaire (IIQ-7) was filled in only by the women in the UI group. Unpaired t-tests and the general …
Clinical And Electrophysiological Evaluation Of Shoulder Functions In Spinal Accessory Nerve-Preserving Neck Dissection, Özgür Tarkan, Ülkü Tuncer, Hacer Bozdemi̇r, Tunay Sarpel, Süleyman Özdemi̇r, Özgür Sürmeli̇oğlu
Clinical And Electrophysiological Evaluation Of Shoulder Functions In Spinal Accessory Nerve-Preserving Neck Dissection, Özgür Tarkan, Ülkü Tuncer, Hacer Bozdemi̇r, Tunay Sarpel, Süleyman Özdemi̇r, Özgür Sürmeli̇oğlu
Turkish Journal of Medical Sciences
The aim of this study was to evaluate shoulder functions after neck dissection with preservation of the spinal accessory nerve by objective physical examination, electromyographic findings, and subjective patient complaints, and also to investigate the effect of the type of neck dissection. Materials and methods: The present study included 29 patients on whom unilateral selective or modified radical neck dissection was performed for head and neck cancer and/or metastasis to the neck. Electromyographical findings, range of motion, and pain scores of the shoulder joint were determined for the operated and nonoperated (control) sides. Results: An electromyographic examination of the trapezius …
Antinociceptive Activity Of Some Scorzonera L. Species, Özlem Bahadir Acikara, Hayri̇ye Gülçi̇n Saltan, Hanefi̇ Özbek
Antinociceptive Activity Of Some Scorzonera L. Species, Özlem Bahadir Acikara, Hayri̇ye Gülçi̇n Saltan, Hanefi̇ Özbek
Turkish Journal of Medical Sciences
Scorzonera species are mainly used to relieve pain in Turkish traditional medicine. The roots of Scorzonera latifolia (Fisch. & Mey) DC., S. tomentosa L., S. suberosa C.Koch subsp. suberosa, and S. mollis M.Bieb. subsp. szowitzii collected from different regions of Anatolia, and yakı sakızı, which is prepared by drying the latex obtained from the roots of Scorzonera latifolia, were evaluated for their antinociceptive activities. Materials and methods: For antinociceptive evaluation, Scorzonera latifolia (Fisch. & Mey) DC., S. tomentosa L., S. suberosa C.Koch subsp. suberosa, S. mollis M.Bieb. subsp. szowitzii, and yakı sakızı were tested on mice, and acetic acid-induced writhing …
The Effect Of Early Loss Of Anterior Primary Tooth On Speech Production In Preschool Children, Melek Di̇lek Turgut, Gülsüm Aydan Genç, Fi̇gen Başar, Meryem Uzamiş Tekçi̇çek
The Effect Of Early Loss Of Anterior Primary Tooth On Speech Production In Preschool Children, Melek Di̇lek Turgut, Gülsüm Aydan Genç, Fi̇gen Başar, Meryem Uzamiş Tekçi̇çek
Turkish Journal of Medical Sciences
Early childhood caries (ECC) is a progressive dental caries in children that may cause premature loss of the anterior primary teeth. In this study, the aim was to investigate the effects of primary anterior tooth loss and removable dentures on the speech of children with ECC. Materials and methods: Included in the study were 15 patients with ECC who required extraction of the primary anterior teeth and needed dentures (case group), and 15 healthy children (control group). The articulation of the control group was evaluated once and that of the case group was evaluated before and after extraction, before and …
Characteristics Of Patients Transferred By Air: A Descriptive Epidemiologic Study, Ataman Köse, Beri̇l Köse, Ayça Açikalin Akpinar, Özlem Köksal, Şule Aydin, Erol Armağan
Characteristics Of Patients Transferred By Air: A Descriptive Epidemiologic Study, Ataman Köse, Beri̇l Köse, Ayça Açikalin Akpinar, Özlem Köksal, Şule Aydin, Erol Armağan
Turkish Journal of Medical Sciences
To analyze the characteristics of patients transferred by air ambulance in the eastern Anatolia region of Turkey. Materials and methods: We retrospectively evaluated the records of patients transferred by air ambulance between January 2010 and December 2010. Demographics and medical data of the patients, geographic conditions, and flight duration data were all analyzed. Results: A total of 241 patients were included in the study, of whom 51% were men and 49% were women. The majority of the patients were between 0 and 1 year old (40.2%). In the adult patients, the most commonly seen diagnoses were trauma (31.6%), obstetric problems …
Prediction Of Mortality In Stroke Patients Using Multilayer Perceptron Neural Networks, Necdet Süt, Yahya Çeli̇k
Prediction Of Mortality In Stroke Patients Using Multilayer Perceptron Neural Networks, Necdet Süt, Yahya Çeli̇k
Turkish Journal of Medical Sciences
We aim ed to predict mortality in stroke patients by using multilayer perceptron (MLP) neural networks. Materials and methods: A data set consisting of 584 stroke patients was analyzed using MLP neural networks. The effect of prognostic factors (age, hospitalization time, sex, hypertension, atrial fibrillation, embolism, stroke type, infection, diabetes mellitus, and ischemic heart disease) on mortality in stroke were trained with 6 different MLP algorithms [quick propagation (QP), Levenberg-Marquardt (LM), backpropagation (BP), quasi-Newton (QN), delta bar delta (DBD), and conjugate gradient descent (CGD)]. The performances of the MLP neural network algorithms were compared using the receiver operating characteristic (ROC) …
The Effects Of Stobadine On Purine Metabolism In Rats Treated With Carbon Tetrachloride, Ni̇lüfer Bayrakdar, Seda Duygulu Devay, Mi̇ne Yavuz Taşlipinar, Suna Ömeroğlu, Seyhan Gümüşlü, Mustafa Kavutçu, Orhan Canbolat
The Effects Of Stobadine On Purine Metabolism In Rats Treated With Carbon Tetrachloride, Ni̇lüfer Bayrakdar, Seda Duygulu Devay, Mi̇ne Yavuz Taşlipinar, Suna Ömeroğlu, Seyhan Gümüşlü, Mustafa Kavutçu, Orhan Canbolat
Turkish Journal of Medical Sciences
The aim of the present study was to investigate the relationship between liver damage induced by carbon tetrachloride (CCl_4) and adenosine deaminase (ADA), 5'-nucleotidase (5'NT), xanthine oxidase (XO) enzyme activities, and malondialdehyde (MDA) levels. The effect of stobadine on purine metabolism was also evaluated. Materials and methods: This study measured the effect of CCl_4 on ADA, 5'NT, XO enzyme activities, and MDA levels, and measured the histopathologic changes in liver cells. Results: Our research found that ADA, XO activities, and MDA levels increased in the CCl_4 group when compared with the control group. This was also supported by the histopathological …
Effects Of L-2-Oxоthiazolidine-4-Carboxylic Acid On The Lung Antioxidant Defense System In An Asthma Mouse Model, Lyudmil Georgiev Terziev, Veneta Lyubenova Shopova, Violeta Yordanova Dancheva, Galya Tzvetanova Stavreva, Angelina Milcheva Stoyanova
Effects Of L-2-Oxоthiazolidine-4-Carboxylic Acid On The Lung Antioxidant Defense System In An Asthma Mouse Model, Lyudmil Georgiev Terziev, Veneta Lyubenova Shopova, Violeta Yordanova Dancheva, Galya Tzvetanova Stavreva, Angelina Milcheva Stoyanova
Turkish Journal of Medical Sciences
We aim ed to study the effect of a glutathione precursor, L-2-oxothiazolidine-4-carboxylic acid (OTCA), on the lung antioxidant defense system in an animal asthma model. Materials and methods: The study was carried out on 24 female C57BL/6 mice. The mice were divided into 4 treatment groups: group 1 - control group; group 2 - injected with ovalbumin (OVA) and given an OVA inhalant; group 3 - treated with OTCA and phosphate-buffered saline inhalant; and group 4 -injected with OVA and OTCA and given an OVA inhalant. Under sodium pentobarbital anesthesia the animals were killed by exsanguination 48 h after the …
Rating Of Perceived Exertion In Cycle Ergometer: Effect Of Maximal Capacity Difference, Özgür Kasimay Çakir, Bariş Çakir, Ömer Utku Erzengi̇n, Hizir Kurtel
Rating Of Perceived Exertion In Cycle Ergometer: Effect Of Maximal Capacity Difference, Özgür Kasimay Çakir, Bariş Çakir, Ömer Utku Erzengi̇n, Hizir Kurtel
Turkish Journal of Medical Sciences
The purpose of this study was to evaluate cardiopulmonary responses of individuals with different fitness levels according to predetermined rating of perceived exertion (RPE) scores and to investigate the correspondence between the heart rate reserve percentage (HRR%) and the RPE scale by using fit and unfit subjects. Materials and methods: RPE scores of sedentary volunteers were recorded at different HRR% levels during graded exercise tests on a cycle ergometer. Following the tests, subjects were divided into 2 groups, high metabolic equivalent [(MET) MET >= 10; n = 9] and low MET (MET < 10; n = 11), according to maximal O_2 uptakes (VO_{2max}). Participants performed the steady-state exercise test at the 13th-14th level of their perceived exertion 48 h after the first test. Variance and regression analyses were performed. Results: For all HRR% values, RPE levels were not different between groups. During the graded exercise test, perceived exertion was significantly higher in the low MET group than in the high MET group. Predetermined RPE score results were significantly greater in the low MET group with relative O2 consumption as compared to the high MET group (P < 0.05-0.001). Conclusion: In individuals with different VO_{2max} levels, exercise intensity can be prescribed using HRR% or RPE scale methods while adjusting for individual differences in oxygen consumption.
Sciatic Nerve Injury Due To Intramuscular Injection: Electrophysiological Findings And One-Year Follow-Up, Selda Bağiş, Mehmet Adam, Ümmühan Berri̇n Leblebi̇ci̇, Meti̇n Karataş, Adi̇le Zeynep Güven, Ayşe Reyhan Çeli̇ker
Sciatic Nerve Injury Due To Intramuscular Injection: Electrophysiological Findings And One-Year Follow-Up, Selda Bağiş, Mehmet Adam, Ümmühan Berri̇n Leblebi̇ci̇, Meti̇n Karataş, Adi̇le Zeynep Güven, Ayşe Reyhan Çeli̇ker
Turkish Journal of Medical Sciences
To investigate the electrophysiological findings of sciatic nerve injury following intramuscular injection and follow-up progression. Materials and methods: Included in the study were 26 patients (16 men, 10 women) with sciatic nerve injuries due to intramuscular injections who were admitted to our electrophysiology laboratory. The age, sex, and body mass index (BMI), along with the clinical and electrophysiological findings of each of the patients, were recorded. Tibial and peroneal nerve motor conduction studies, sural and superficial peroneal nerve sensorial conduction studies, and needle electromyography were performed. The patients were reevaluated for electrophysiological evaluation at 3 and 6 months and 1 …
Limb Remote Ischemic Postconditioning Is Effective But Also Time-Course-Limited In Protecting The Brain From I/R Injury, Ce Xu, Chengju Yi, Haidong Guo, Qiangqiang Liu, Li Wang, Hongxia Li
Limb Remote Ischemic Postconditioning Is Effective But Also Time-Course-Limited In Protecting The Brain From I/R Injury, Ce Xu, Chengju Yi, Haidong Guo, Qiangqiang Liu, Li Wang, Hongxia Li
Turkish Journal of Medical Sciences
To determine the effect of limb remote ischemic postconditioning (LIPoC) against cerebral ischemia reperfusion in rats and the relationship between cycle number or remote postconditioning episode duration and the protective function of LIPoC. Materials and methods: Transient focal ischemia/reperfusion was induced by 90 min of middle cerebral artery occlusion (MCAO) with nylon monofilament and 22 h of reperfusion in male Sprague-Dawley rats. The animals underwent LIPoC consisting of 1, 2, or 3 cycles, with each occlusion or release lasting for 5 min (5/5), 10 min (10/10), or 15 min (15/15) of bilateral femoral artery occlusion/release. Neurological score, infarct volume, water …
Development Of A High-Performance Liquid Chromatography Method For Warfarin Detection In Human Plasma, Yung An Chua, Wan Zaidah Abdullah, Siew Hua Gan
Development Of A High-Performance Liquid Chromatography Method For Warfarin Detection In Human Plasma, Yung An Chua, Wan Zaidah Abdullah, Siew Hua Gan
Turkish Journal of Medical Sciences
Most of the high-performance liquid chromatography (HPLC) methods that have been developed to measure warfarin levels use the preextraction spiked internal standard method. We developed a new liquid-liquid extraction (LLE) and reversed-phase HPLC method that uses a postextraction spiked internal standard for the determination of plasma warfarin. Materials and methods: The effect of varying the 1) mobile phase pH, 2) type and composition of organic solvents, 3) type and concentration of buffer solutions, 4) column temperatures, 5) flow rates, 6) organic modifier, and 7) ultraviolet wavelengths were tested. Results: Optimum separation was achieved by using 30:70 (v/v) acetonitrile and potassium …
Final Baricity Of Ropivacaine Or Bupivacaine Combined With Fentanyl For Intrathecal Administration, Berri̇n Günaydin, İrfan Güngör, Seval İzdeş
Final Baricity Of Ropivacaine Or Bupivacaine Combined With Fentanyl For Intrathecal Administration, Berri̇n Günaydin, İrfan Güngör, Seval İzdeş
Turkish Journal of Medical Sciences
We determined the baricity of fentanyl-added bupivacaine or ropivacaine with or without dextrose by analyzing the specific gravity for a better understanding of the final baricity of the intrathecal drug combinations that are supposed to be used for surgery.
Long-Term Results Of Pancreaticoduodenectomy And Endoscopic Resection In The Treatment Of Early Stage Carcinoma Of The Ampulla Of Vater: Case Series And Review Of The Literature, Abdulkadi̇r Dökmeci̇, Mustafa Yakut, Necati̇ Örmeci̇, Hasan Özkan, Gökhan Kabaçam
Long-Term Results Of Pancreaticoduodenectomy And Endoscopic Resection In The Treatment Of Early Stage Carcinoma Of The Ampulla Of Vater: Case Series And Review Of The Literature, Abdulkadi̇r Dökmeci̇, Mustafa Yakut, Necati̇ Örmeci̇, Hasan Özkan, Gökhan Kabaçam
Turkish Journal of Medical Sciences
We retrospectively evaluated 6 cases to explore the role of curative pancreaticoduodenectomy and endoscopic resection of ampulla of Vater tumors. Six patients diagnosed with stage 1 ampullary tumors at Ankara University Hospital between January 1994 and September 2009 were analyzed retrospectively. Icterus was the cardinal symptom in all patients. The median time for the symptoms caused by the lesion of the papilla was 7 weeks in patients with carcinoma. The diameters of the visualized tumors were less than 20 mm. Diabetes mellitus was observed in 2 patients. When the patients were classified according to TNM staging, all patients were in …
Urodynamic Evaluation Of Acute Effects Of Sildenafil On Voiding Among Males With Erectile Dysfunction And Symptomatic Benign Prostate, Fati̇h Rüştü Yalçinkaya, Mürsel Davarci, Soner Akçi̇n, Ahmet Gökçe, Eşref Oğuz Güven, Mehmet İnci̇, Mevlana Derya Balbay
Urodynamic Evaluation Of Acute Effects Of Sildenafil On Voiding Among Males With Erectile Dysfunction And Symptomatic Benign Prostate, Fati̇h Rüştü Yalçinkaya, Mürsel Davarci, Soner Akçi̇n, Ahmet Gökçe, Eşref Oğuz Güven, Mehmet İnci̇, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
To evaluate the acute effects of sildenafil citrate on micturition of men with erectile dysfunction and symptomatic benign prostatic hyperplasia using urodynamic parameters. Materials and methods: Between June and December 2009, a total of 50 patients over the age of 40 participated in the study. The patients were admitted to our hospital with erectile dysfunction and moderate to severe lower urinary symptoms with benign prostatic hyperplasia. To examine the sexual function of the participants, we used the IIEF-5 Sexual Health Inventory for Men questionnaire. Patients were randomly divided into 2 groups: a treatment group and a control group. A basal …
Prevalence And Etiology Of Anemias In The Adult Turkish Population, Ramazan Memi̇şoğullari, Hayri̇ye Ak Yildirim, Taner Uçgun, Meli̇h Engi̇n Erkan, Cemaletti̇n Güneş, Mesut Erbaş, Adem Güngör, Mehmet Emi̇n Yanik
Prevalence And Etiology Of Anemias In The Adult Turkish Population, Ramazan Memi̇şoğullari, Hayri̇ye Ak Yildirim, Taner Uçgun, Meli̇h Engi̇n Erkan, Cemaletti̇n Güneş, Mesut Erbaş, Adem Güngör, Mehmet Emi̇n Yanik
Turkish Journal of Medical Sciences
Anemia is common in the general population and one of the most frequently observed nutritional deficiency diseases in the world today. The aim of this study was to investigate the prevalence and etiology of anemias in a large cohort representing the Turkish nation. Materials and methods: The study population comprised 2187 subjects. Serum iron, iron binding capacity, ferritin, vitamin B12, and folic acid analyses were conducted with autoanalyzers using commercial kits. Results: A total of 565 (25.8%) subjects (423 females and 142 males) were diagnosed as anemic. The prevalence of anemia was 30.0% in female and 18.2% in male participants. …
Heart Rate Recovery In Patients With Obstructive Sleep Apnea Syndrome, Riza Murat Karaşen, Bülent Çi̇ftçi̇, Ahmet Ari̇f Yalçin, Baran Acar, Selma Firat Güven
Heart Rate Recovery In Patients With Obstructive Sleep Apnea Syndrome, Riza Murat Karaşen, Bülent Çi̇ftçi̇, Ahmet Ari̇f Yalçin, Baran Acar, Selma Firat Güven
Turkish Journal of Medical Sciences
To demonstrate the effects of obstructive sleep apnea syndrome (OSAS) on baroregulatory function by using heart rate recovery (HRR) parameters. Materials and methods: Fifty-four moderate and severe OSAS patients were included in the study. HRR was defined as the difference in heart rate between peak exercise and 1 min later; a value of 18 beats/min was considered abnormal. OSAS patients were enrolled in the study as group 1 (normal HRR; n = 12) and group 2 (abnormal HRR, n = 42). Left ventricular ejection fraction (LVEF, %) and other parameters were also measured by echocardiography in both groups. Results: There …
The Oral Health Status Of Healthy And Obese Children In A Turkish Population: A Cross-Sectional Study, Günseli̇ Güven Polat, Sevi̇ Burçak Çehreli̇, Mehmet Emre Taşcilar, Özlem Marti Akgün, Ceyhan Altun, İlker Tolga Özgen
The Oral Health Status Of Healthy And Obese Children In A Turkish Population: A Cross-Sectional Study, Günseli̇ Güven Polat, Sevi̇ Burçak Çehreli̇, Mehmet Emre Taşcilar, Özlem Marti Akgün, Ceyhan Altun, İlker Tolga Özgen
Turkish Journal of Medical Sciences
To compare the oral health status of a group of obese and healthy Turkish children. Materials and methods: The study involved 43 healthy (19 boys and 24 girls, mean age: 9.88) and 53 obese (18 boys and 35 girls, mean age: 10.4) children who were admitted to a pediatric dentistry clinic in 2008 and 2009. The parents were asked to complete a questionnaire concerning medical history and dietary/oral hygiene habits. The number of decayed, missing, and filled permanent teeth (DMFT); number of decayed, missing, and filled primary teeth (dmft); and gingival bleeding index (GBI) scores of patients were recorded. Statistical …
Do Incubation Temperature, Incubation Time, And Carbon Dioxide Affect The Chromogenic Properties Of Chromagar?, Di̇lek Yeşi̇m Meti̇n, Hüsnü Pullukçu, Süleyha Hi̇lmi̇oğlu Polat, Ramazan İnci̇, Zeki̇ye Emel Tümbay
Do Incubation Temperature, Incubation Time, And Carbon Dioxide Affect The Chromogenic Properties Of Chromagar?, Di̇lek Yeşi̇m Meti̇n, Hüsnü Pullukçu, Süleyha Hi̇lmi̇oğlu Polat, Ramazan İnci̇, Zeki̇ye Emel Tümbay
Turkish Journal of Medical Sciences
On CHROMagar medium Candida species form different colors; thus, the medium enables the differentiation of these species from each other as well as from other Candida species. The aim of this study is to investigate the effect of incubation temperatures, incubation times, and CO_2 on the chromogenic properties of CHROMagar. Materials and methods: A total of 112 strains of Candida spp. were used. A 0.5 McFarland suspension of each strain was inoculated onto CHROMagar with a calibrated loop and incubated at 26 °C and 35 °C for 24-48 h in normal atmosphere and in an atmosphere of 5% CO_2. The …
Cyp2c9 Gene Polymorphisms And Warfarin Dose Requirement: A Single-Center Experience In Turkey, Rahşan Yildirim, Mehmet Gündoğdu, Fati̇h Kurnaz, Abdulkadi̇r Yildirim, Hülya Aksoy, Fuat Erdem, İlhami̇ Ki̇ki̇, Emi̇n Murat Akbaş, Serkan Cerrah
Cyp2c9 Gene Polymorphisms And Warfarin Dose Requirement: A Single-Center Experience In Turkey, Rahşan Yildirim, Mehmet Gündoğdu, Fati̇h Kurnaz, Abdulkadi̇r Yildirim, Hülya Aksoy, Fuat Erdem, İlhami̇ Ki̇ki̇, Emi̇n Murat Akbaş, Serkan Cerrah
Turkish Journal of Medical Sciences
In this study, we aimed to evaluate the relationship between genetic structure and daily dose requirement in patients under warfarin therapy presenting at our hospital. Materials and methods: A total of 80 patients (45 female and 35 male) aged between 29 and 80 years (mean age: 59.86 ± 14.46 years), using warfarin for at least 1 month and presenting at Atatürk University Medical Faculty Outpatient Clinic between May 2009 and May 2010, were included in the study. Analysis of CYP2C9 1075 A>C and CYP2C9 430 C>T polymorphisms were performed using polymerase chain reaction (PCR) and the reverse-hybridization method. …
Evaluation Of The Relationship Between Obstructive Sleep Apnea Syndrome Severity And Cephalometric And Clinical Variables, Süleyman Hakan Tuna, Önder Öztürk, Muhammet Hakan Türkkahraman, Hüseyi̇n Alkiş, Hüseyi̇n Avni̇ Balcioğlu, Ahmet Akkaya
Evaluation Of The Relationship Between Obstructive Sleep Apnea Syndrome Severity And Cephalometric And Clinical Variables, Süleyman Hakan Tuna, Önder Öztürk, Muhammet Hakan Türkkahraman, Hüseyi̇n Alkiş, Hüseyi̇n Avni̇ Balcioğlu, Ahmet Akkaya
Turkish Journal of Medical Sciences
To evaluate the cephalometric features of patients with obstructive sleep apnea syndrome (OSAS) and to elucidate the relationship between the severity of OSAS and cephalometric and clinical variables. Materials and methods: Ninety-three patients (71M/22W) with OSAS were classified into 3 subgroups according to the apnea-hypopnea index (AHI). Various cephalometric and clinical measurements were carried out for all patients. Results: Inferior airway space (IAS), maximum soft palate thickness (MSPT), SNGoGn°, and distance of hyoid bone to mandibular plane (Hy-MPPerp) were found to be higher in severe OSAS for both sexes. Middle airway space, IAS, MSPT, and Hy-MPPerp were correlated positively with …
Maternal Smoking During Pregnancy And Effects On Neonatal Anthropometry: A Prospective Study, Fati̇h Bolat, Özge Eren, Güher Bolat, Emrah Can, Serdar Cömert, Hasan Si̇nan Uslu, Asi̇ye Nuhoğlu
Maternal Smoking During Pregnancy And Effects On Neonatal Anthropometry: A Prospective Study, Fati̇h Bolat, Özge Eren, Güher Bolat, Emrah Can, Serdar Cömert, Hasan Si̇nan Uslu, Asi̇ye Nuhoğlu
Turkish Journal of Medical Sciences
To identify risk factors associated with cigarette smoking during pregnancy and to evaluate the effect of smoking on anthropometric measurements. Materials and methods: This study was carried out prospectively in selected women who gave birth to a healthy, term infant at Şişli Etfal Education and Research Hospital from January 2009 to January 2010. Smoking status during pregnancy was categorized into 3 groups: nonsmoker; smoker; passive smoker. Regression analysis was performed to compare risk factors with cigarette smoking. Results: A total of 1175 mothers were enrolled. Active and passive smoking rates were 14.9% and 32.3%, respectively. In univariate analysis, maternal active …
The Prevalence Of Pterygium In Ankara: A Hospital-Based Study, Özge Saraç, Yasi̇n Toklu, Mehmet Şahi̇n
The Prevalence Of Pterygium In Ankara: A Hospital-Based Study, Özge Saraç, Yasi̇n Toklu, Mehmet Şahi̇n
Turkish Journal of Medical Sciences
The prevalence of pterygium in a hospital-based population was analyzed in Ankara, in central Turkey. Materials and methods: This was a retrospective, nonrandomized, and consecutive case study. The medical records of 6470 consecutive patients aged 40 and above who attended the general ophthalmology clinic during a 12-month period from May 2008 to May 2009 were evaluated for the presence of pterygium. Results: The overall prevalence of pterygium was found to be 3.0 % (95% confidence interval (CI): 1.9 to 3.8). It was 3.2% (95% CI: 1.9 to 4.5) and 2.8% (95% CI: 1.4 to 4.5) in men and women, respectively …
Early Oxidative Status In Adult Patients With Isolated Traumatic Brain Injury, Özgür Söğüt, Hali̇l Kaya, Mehmet Tahi̇r Gökdemi̇r, Leyla Solduk, Mehmet Aki̇f Dokuzoğlu, Mustafa Burak Sayhan, Atilhan Kaya, Abdürrahi̇m Koçyi̇ği̇t
Early Oxidative Status In Adult Patients With Isolated Traumatic Brain Injury, Özgür Söğüt, Hali̇l Kaya, Mehmet Tahi̇r Gökdemi̇r, Leyla Solduk, Mehmet Aki̇f Dokuzoğlu, Mustafa Burak Sayhan, Atilhan Kaya, Abdürrahi̇m Koçyi̇ği̇t
Turkish Journal of Medical Sciences
To investigate oxidative and antioxidative status, as well as the Glasgow Coma Scale (GCS) and Revised Trauma Score (RTS), reflecting injury severity and neurological outcome during the early posttraumatic period in patients with isolated traumatic brain injury (TBI). Materials and methods: Fifty-one adult patients with TBI and 45 eligible healthy volunteers as control subjects were enrolled. Plasma total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) were calculated as biomarkers of early oxidative changes in serum using a novel automated method. Results: TOS levels and OSI values were significantly higher in nonsurvivors compared with those …
Hyaluronidase-1 Expression Is Not A Predictor Of Biochemical Recurrence In Radical Prostatectomy Specimens, Bayram Güner, Sidika Şeyma Özkanli, Turhan Çaşkurlu, Asif Yildirim, Mehmet Cenk Gürbüz, Itir Ebru Zemheri̇
Hyaluronidase-1 Expression Is Not A Predictor Of Biochemical Recurrence In Radical Prostatectomy Specimens, Bayram Güner, Sidika Şeyma Özkanli, Turhan Çaşkurlu, Asif Yildirim, Mehmet Cenk Gürbüz, Itir Ebru Zemheri̇
Turkish Journal of Medical Sciences
The purposes of this study were to evaluate the rate of biochemical recurrence among patients who underwent radical prostatectomy due to localized prostate cancer, assess the risk factors of biochemical recurrence, and investigate its relation with hyaluronidase-1 (HYAL-1). Materials and methods: We retrospectively evaluated the data of 112 patients who underwent radical retropubic prostatectomy. HYAL-1 expression was evaluated immunohistochemically and staining was graded as mild, moderate, and severe. Two blinded pathologists evaluated the specimens. The relation among preoperative pathologic findings that were detected in transrectal ultrasound (TRUS) guided biopsy, specimens of radical prostatectomy in the final stage, and biochemical recurrence …