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Articles 31 - 60 of 215
Full-Text Articles in Medicine and Health Sciences
Tissue Damage In Abdominal Hysterectomy Performed With A Vessel Sealing System, Ilgin Türkçüoğlu, Ayşe Kafkasli, Çağdaş Doğan, Emrullah Tanrikut
Tissue Damage In Abdominal Hysterectomy Performed With A Vessel Sealing System, Ilgin Türkçüoğlu, Ayşe Kafkasli, Çağdaş Doğan, Emrullah Tanrikut
Turkish Journal of Medical Sciences
To compare the tissue damage, operation times, blood loss, short-term postoperative complication rates, and hospitalization durations of abdominal hysterectomies performed due to benign gynecological conditions using the LigaSure vessel sealing system (LVSS) and conventional suture ligation. Materials and methods: Patients were prospectively enrolled in LVSS (TAH-L group, 22 cases) and suture ligation (TAH-S group, 31 cases) groups. Anesthesia time, operation time, intraoperative blood loss, intraoperative and short-term postoperative complications, and hospitalization durations were compared between the groups. Tissue damage was assessed by comparing changes in C-reactive protein, creatine phosphokinase levels, and white blood cell counts on preoperative and postoperative days …
Anesthesia, Complications, And Clinical Outcome For Ruptured Intracranial Aneurysms: A Retrospective Comparison Between Endovascular Coiling And Neurosurgical Clipping, Vladimir Vrsajkov, Radmila Kolak, Anna Uram-Benka, Arsen Uvelin, Jasenka Kiselicki
Anesthesia, Complications, And Clinical Outcome For Ruptured Intracranial Aneurysms: A Retrospective Comparison Between Endovascular Coiling And Neurosurgical Clipping, Vladimir Vrsajkov, Radmila Kolak, Anna Uram-Benka, Arsen Uvelin, Jasenka Kiselicki
Turkish Journal of Medical Sciences
To compare anesthetic practice, perioperative complications, and clinical outcomes of endovascular coiling versus neurosurgical clipping in our university hospital over a 2-year period. Materials and methods: This was a retrospective review of the hospital charts of 30 patients with cerebral aneurysms treated by endovascular coiling compared with 52 patients treated by neurosurgical clipping. Information including demographics, preoperative neurological status, timing of intervention, anesthetic management, duration of the postoperative intensive care and hospital stay, intra- and postoperative complications, and clinical outcome at hospital discharge were compared and analyzed. P < 0.05 was considered to be significant. Results: The surgical group had greater consumption of certain anesthetic agents whereas the endovascular group had more frequent episodes of hypertension (>30% more than the baseline measurement) during the procedure. We recorded significantly …
Oxidative Stress Status Of Individuals Involved In Traffic Accidents*, Bora Özdemi̇r, Atilhan Kaya, Özgür Söğüt, Hali̇l Kaya, Mehmet Tahi̇r Gökdemi̇r, Osman Celbi̇ş
Oxidative Stress Status Of Individuals Involved In Traffic Accidents*, Bora Özdemi̇r, Atilhan Kaya, Özgür Söğüt, Hali̇l Kaya, Mehmet Tahi̇r Gökdemi̇r, Osman Celbi̇ş
Turkish Journal of Medical Sciences
To investigate the role of the oxidative stress status of drivers involved in traffic accidents as a risk factor. Materials and methods: Twenty-six drivers and 28 passengers involved in traffic accidents and 31 healthy control drivers and 30 healthy control pedestrians were enrolled in the present study. The total antioxidant status (TAS) and total oxidant status (TOS) were measured in blood samples. Results: The mean value of the TOS level in drivers involved in traffic accidents was significantly higher than that of the control pedestrians (P =< 0.05). The mean value of the TAS level in passengers involved in traffic accidents was significantly lower than that of the control drivers and pedestrians (P =< 0.001 and P =< 0.01, respectively). Conclusion: This is the first study assessing the oxidative markers of individuals involved in a traffic accident compared with a control group. The results reveal that involvement in a traffic accident has an effect on oxidative markers. However, further studies are required in order to use the oxidative stress status of drivers involved in traffic accidents as a marker for estimating the accident risk.
Bother Index Can Be Used In Deciding How The Symptom Nocturia Itself Is Important, Ahmet Tunç Özdemi̇r, Haci İbrahi̇m Çi̇men, Serkan Altinova, Ali̇ Fuat Atmaca, Ege Can Şerefoğlu, Mevlana Derya Balbay
Bother Index Can Be Used In Deciding How The Symptom Nocturia Itself Is Important, Ahmet Tunç Özdemi̇r, Haci İbrahi̇m Çi̇men, Serkan Altinova, Ali̇ Fuat Atmaca, Ege Can Şerefoğlu, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
Aim: To report the prevalence of nocturia. Associated risk factors and bother in various age groups (by decade) were evaluated in order to determine the characteristics of individuals who may need medical help. Materials and methods: To estimate the extent to which patients were bothered relative to nocturia in various age groups (by decade), a descriptive figure, the "bother index," was used. The bother index was calculated by dividing the number of individuals reporting a bother score higher than a symptom score by the number of individuals reporting a bother score lower than a symptom score in the same age …
Effects Of Neoadjuvant Chemotherapy On Pathological Parameters And Survival In Patients Undergoing Radical Cystectomy For Muscle-Invasive Bladder Cancer, Alper Çağlayan, Zi̇ya Akbulut, Ali̇ Fuat Atmaca, Serkan Altinova, Meti̇n Kiliç, Mevlana Derya Balbay
Effects Of Neoadjuvant Chemotherapy On Pathological Parameters And Survival In Patients Undergoing Radical Cystectomy For Muscle-Invasive Bladder Cancer, Alper Çağlayan, Zi̇ya Akbulut, Ali̇ Fuat Atmaca, Serkan Altinova, Meti̇n Kiliç, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
Aim: To evaluate the effect of neoadjuvant chemotherapy on tumor pathology and patient survival in patients with muscle-invasive bladder cancer undergoing radical cystectomy. Neoadjuvant chemotherapy is believed to prevent micrometastasis and provide pathological downstaging. Materials and methods: Between June 2004 and March 2009, 74 patients with muscle-invasive bladder cancer were treated with radical cystectomy. Patients fit to receive chemotherapy were administered systemic chemotherapy of methotrexate, vinblastine, Adriamycin, and cisplatin (MVAC); gemcitabine and cisplatin (GC); or carboplatin and gemcitabine (CG). Patients in Group 1 (n = 36) did not receive any chemotherapy, while the remaining 38 patients in Group 2 did …
Iodine Deficiency In Pregnancy And In Women Of Reproductive Age In Erzurum, Turkey, Kadi̇r Çeti̇nkaya, Meti̇n İngeç, Semra Çeti̇nkaya, İbrahi̇m Kaplan
Iodine Deficiency In Pregnancy And In Women Of Reproductive Age In Erzurum, Turkey, Kadi̇r Çeti̇nkaya, Meti̇n İngeç, Semra Çeti̇nkaya, İbrahi̇m Kaplan
Turkish Journal of Medical Sciences
Aim: Iodine deficiency (ID) is an important public health problem and the most common cause of preventable mental retardation. The aims of this study were to determine the urinary iodine concentration (UIC) of pregnant women living in Erzurum, to assess the ID rate, and to find out whether iodine supplementation is necessary in pregnancy. Materials and methods: Spot urine was obtained from pregnant and nonpregnant women with no functional or organic thyroid disease. The UIC was studied using the Sandell-Kolthoff method. Results: The median UIC values of pregnant women in the first, second, and third trimesters and of the nonpregnant …
A Combination Therapy Of Half-Dose Verteporfin Photodynamic Therapy And Intravitreal Injection Of Ranibizumab For Chronic Central Serous Chorioretinopathy, Yasi̇n Toklu, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Şule Berk Ergun, Şaban Şi̇mşek
A Combination Therapy Of Half-Dose Verteporfin Photodynamic Therapy And Intravitreal Injection Of Ranibizumab For Chronic Central Serous Chorioretinopathy, Yasi̇n Toklu, Hasan Basri̇ Çakmak, Mücella Arikan Yorgun, Şule Berk Ergun, Şaban Şi̇mşek
Turkish Journal of Medical Sciences
Aim: To study the combination treatment consisting of half-dose verteporfin photodynamic therapy (PDT) and an intravitreal injection of ranibizumab as a potential treatment for patients with chronic central serous chorioretinopathy (CSC). Materials and methods: Six eyes of 6 patients were studied with fundus examination, fluorescein angiography, and optical coherence tomography to diagnose the maculopathy, monitor the detachments, and localize the choroidal hyperpermeability of the disorder. Half-dose verteporfin PDT was applied to areas of choroidal hyperpermeability and, the following day, 0.5 mg/0.05 mL ranibizumab was injected intravitreally. The patients were observed to determine the anatomic and functional outcomes. Results: The combination …
Biochemical And Structural Changes Of The Kidney In Mice Exposed To Phenol, Zahra Tootian, Ali Louei Monfared, Simin Fazelipour, Mohammad Taghi Shybani, Fatemeh Rouhollah, Farhang Sasani, Ebrahim Molaemi
Biochemical And Structural Changes Of The Kidney In Mice Exposed To Phenol, Zahra Tootian, Ali Louei Monfared, Simin Fazelipour, Mohammad Taghi Shybani, Fatemeh Rouhollah, Farhang Sasani, Ebrahim Molaemi
Turkish Journal of Medical Sciences
Aim: To investigate the histology and function of the kidney in mice exposed to different concentrations of phenol through the gavage method for 10 consecutive days. Materials and methods: Forty female BALB/c mice were selected and randomly divided into 1 control group and 3 experimental groups. The control group was administered distilled water through the gavage method, while the experimental groups received daily doses of 80, 180, and 320 mg/kg of phenol, respectively. After 10 days, blood samples were collected and the sera were analyzed biochemically. Renal tissue samples were also taken and histopathological changes of the kidneys were examined …
Cortical And Medullary Vascularity In Renal Allograft Biopsies, Şadi̇ye Mehtat Ünlü, Ali̇ Çeli̇k, Funda Sağlam Eyi̇ler, Si̇bel Ersan, Sülen Sarioğlu
Cortical And Medullary Vascularity In Renal Allograft Biopsies, Şadi̇ye Mehtat Ünlü, Ali̇ Çeli̇k, Funda Sağlam Eyi̇ler, Si̇bel Ersan, Sülen Sarioğlu
Turkish Journal of Medical Sciences
Aim: To evaluate the relation between cortical and medullary peritubular capillaries (PTCs) and scarring. There are presently no studies about medullary PTCs in renal allograft biopsies. Materials and methods: Nonprotocol allograft biopsies were evaluated and 41 with adequate medullary and cortical tissues were selected. Vascular structures were counted separately at the medulla and cortex on anti-CD34 stained sections. Other histopathological and clinical findings were retrieved from the patient files. Results: A weak but positive correlation was found between the number of cortical vascular structures (nVC) and medullary vascular structures (nVM). The nVC and nVM were decreased in cases with increased …
Effects Of Depression And Life Factors On Social Network Score In Elderly People In Çankaya, Ankara, Meti̇n Canbal, İrfan Şencan, Ayfer Şahi̇n, Şeyda Kunt, Umut Yücel Çavuş, Oğuz Teki̇n
Effects Of Depression And Life Factors On Social Network Score In Elderly People In Çankaya, Ankara, Meti̇n Canbal, İrfan Şencan, Ayfer Şahi̇n, Şeyda Kunt, Umut Yücel Çavuş, Oğuz Teki̇n
Turkish Journal of Medical Sciences
Aim: Social interaction is an important factor in the physical and mental health of seniors. This study was performed in order to evaluate the effects of depression and life factors on the social networking scores of elderly people. Materials and methods: Tests for the Lubben Social Network Scale (LSNS) and Geriatric Depression Scale (GDS) were given to 116 elderly people (>=60 years) in the Çankaya area of Ankara between March and May of 2010. The effects of life factors and GDS scores on LSNS scores were explored. Results: Among the study group, 46.5% of the individuals were male and …
Endovascular Treatment Of Abdominal Aortic Aneurysms With Endologix® Stent Graft: Single-Site Experiences And Short-Term Follow-Up Outcomes, Mustafa Kayan, Turhan Yavuz, Mustafa Etli̇, Şeyma Benzi̇n, Seda İbi̇şoğlu, Esma Di̇lek Üstün, Mert Köroğlu, Ergün Ceylan, Ulaş Sağlam
Endovascular Treatment Of Abdominal Aortic Aneurysms With Endologix® Stent Graft: Single-Site Experiences And Short-Term Follow-Up Outcomes, Mustafa Kayan, Turhan Yavuz, Mustafa Etli̇, Şeyma Benzi̇n, Seda İbi̇şoğlu, Esma Di̇lek Üstün, Mert Köroğlu, Ergün Ceylan, Ulaş Sağlam
Turkish Journal of Medical Sciences
The aim of this study was to investigate the short-term results of endovascular repair of abdominal aortic aneurysms with the Endologix IntuiTrak Powerlink XL® (Endologix) stent graft and to share our clinical experiences in our center. Materials and methods: Endovascular stent graft treatment was applied in 16 cases with infrarenal abdominal aortic aneurysm (13 men and 3 women; mean age: 70.2 years) in 2009 and 2010. Before treatment, all of the patients were examined with 128-slice computed tomography (CT) angiography for the assessment of abdominal aortic aneurysms. The Endologix stent graft (bifurcated system) was used for all of the patients. …
Dysregulation Of Nitric Oxide Synthase Activity And Bcl-2 And Caspase-3 Gene Expressions In Renal Tissue Of Streptozotocin-Induced Diabetic Rats, Hüseyi̇n Aktuğ, Vi̇ldan Bozok Çeti̇ntaş, Buket Kosova, Fati̇h Oltulu, Şi̇ri̇n Bakti Demi̇ray, Türker Çavuşoğlu, Saadet Özen Akarca, Altuğ Yavaşoğlu
Dysregulation Of Nitric Oxide Synthase Activity And Bcl-2 And Caspase-3 Gene Expressions In Renal Tissue Of Streptozotocin-Induced Diabetic Rats, Hüseyi̇n Aktuğ, Vi̇ldan Bozok Çeti̇ntaş, Buket Kosova, Fati̇h Oltulu, Şi̇ri̇n Bakti Demi̇ray, Türker Çavuşoğlu, Saadet Özen Akarca, Altuğ Yavaşoğlu
Turkish Journal of Medical Sciences
To evaluate the effects of diabetes on nitric oxide synthase (NOS) activity and on gene expressions of B-cell lymphoma protein 2 (Bcl-2) and caspase-3 in the renal tissues of streptozotocin (STZ)-induced rats. Materials and methods: Twenty rats were analyzed in 2 equally distributed groups of healthy controls and STZ-induced diabetic rats. Rats with blood glucose levels of >=250 mg/dL were considered diabetic. Renal tissue sections were analyzed histomorphologically and immunohistochemically. Gene expressions of caspase-3 and Bcl-2 were evaluated by real-time quantitative polymerase chain reaction. Results: Bcl-2 expression significantly decreased in the diabetic group, both at the gene and protein level. …
Is The Six-Minute Walk Test Correlated With Disease Control And Quality Of Life In Children With Asthma?, Hasan Yüksel, Özge Yilmaz, Bülent Gökşen, Senem Üstün, Ayhan Söğüt
Is The Six-Minute Walk Test Correlated With Disease Control And Quality Of Life In Children With Asthma?, Hasan Yüksel, Özge Yilmaz, Bülent Gökşen, Senem Üstün, Ayhan Söğüt
Turkish Journal of Medical Sciences
To evaluate the changes in a 6-min walk test (6MWT) and quality of life (QoL) before and after asthma control is achieved in children. A 6MWT is used in the determination of disease severity in many chronic childhood diseases. Materials and methods: Thirty-six asthmatic children, aged 6 to 15 years, were enrolled before asthma control was achieved. Disease severity parameters during the previous 3 months were recorded. All of the children completed an asthma control questionnaire (ACQ) and received a symptom score; a 6MWT was performed during enrollment and 1 month later, when asthma control was achieved. Results: The initial …
Effects Of L-2-Oxоthiazolidine-4-Carboxylic Acid On The Lung Antioxidant Defense System In An Asthma Mouse Model, Lyudmil Georgiev Terziev, Veneta Lyubenova Shopova, Violeta Yordanova Dancheva, Galya Tzvetanova Stavreva, Angelina Milcheva Stoyanova
Effects Of L-2-Oxоthiazolidine-4-Carboxylic Acid On The Lung Antioxidant Defense System In An Asthma Mouse Model, Lyudmil Georgiev Terziev, Veneta Lyubenova Shopova, Violeta Yordanova Dancheva, Galya Tzvetanova Stavreva, Angelina Milcheva Stoyanova
Turkish Journal of Medical Sciences
We aim ed to study the effect of a glutathione precursor, L-2-oxothiazolidine-4-carboxylic acid (OTCA), on the lung antioxidant defense system in an animal asthma model. Materials and methods: The study was carried out on 24 female C57BL/6 mice. The mice were divided into 4 treatment groups: group 1 - control group; group 2 - injected with ovalbumin (OVA) and given an OVA inhalant; group 3 - treated with OTCA and phosphate-buffered saline inhalant; and group 4 -injected with OVA and OTCA and given an OVA inhalant. Under sodium pentobarbital anesthesia the animals were killed by exsanguination 48 h after the …
Sciatic Nerve Injury Due To Intramuscular Injection: Electrophysiological Findings And One-Year Follow-Up, Selda Bağiş, Mehmet Adam, Ümmühan Berri̇n Leblebi̇ci̇, Meti̇n Karataş, Adi̇le Zeynep Güven, Ayşe Reyhan Çeli̇ker
Sciatic Nerve Injury Due To Intramuscular Injection: Electrophysiological Findings And One-Year Follow-Up, Selda Bağiş, Mehmet Adam, Ümmühan Berri̇n Leblebi̇ci̇, Meti̇n Karataş, Adi̇le Zeynep Güven, Ayşe Reyhan Çeli̇ker
Turkish Journal of Medical Sciences
To investigate the electrophysiological findings of sciatic nerve injury following intramuscular injection and follow-up progression. Materials and methods: Included in the study were 26 patients (16 men, 10 women) with sciatic nerve injuries due to intramuscular injections who were admitted to our electrophysiology laboratory. The age, sex, and body mass index (BMI), along with the clinical and electrophysiological findings of each of the patients, were recorded. Tibial and peroneal nerve motor conduction studies, sural and superficial peroneal nerve sensorial conduction studies, and needle electromyography were performed. The patients were reevaluated for electrophysiological evaluation at 3 and 6 months and 1 …
Limb Remote Ischemic Postconditioning Is Effective But Also Time-Course-Limited In Protecting The Brain From I/R Injury, Ce Xu, Chengju Yi, Haidong Guo, Qiangqiang Liu, Li Wang, Hongxia Li
Limb Remote Ischemic Postconditioning Is Effective But Also Time-Course-Limited In Protecting The Brain From I/R Injury, Ce Xu, Chengju Yi, Haidong Guo, Qiangqiang Liu, Li Wang, Hongxia Li
Turkish Journal of Medical Sciences
To determine the effect of limb remote ischemic postconditioning (LIPoC) against cerebral ischemia reperfusion in rats and the relationship between cycle number or remote postconditioning episode duration and the protective function of LIPoC. Materials and methods: Transient focal ischemia/reperfusion was induced by 90 min of middle cerebral artery occlusion (MCAO) with nylon monofilament and 22 h of reperfusion in male Sprague-Dawley rats. The animals underwent LIPoC consisting of 1, 2, or 3 cycles, with each occlusion or release lasting for 5 min (5/5), 10 min (10/10), or 15 min (15/15) of bilateral femoral artery occlusion/release. Neurological score, infarct volume, water …
Microalbumin Excretion And Outcome In Children With Multicystic Dysplastic Kidney, İpek Aki̇l, Neşe Biyikli, Pinar Yazici, Beyhan Cengi̇z Özyurt, Hari̇ka Alpay
Microalbumin Excretion And Outcome In Children With Multicystic Dysplastic Kidney, İpek Aki̇l, Neşe Biyikli, Pinar Yazici, Beyhan Cengi̇z Özyurt, Hari̇ka Alpay
Turkish Journal of Medical Sciences
To present the long-term follow-up results of children with multicystic dysplastic kidney (MCDK) and urinary microalbumin excretion levels in order to evaluate whether there is an increased risk of renal damage or not. Materials and methods: Thirty-three children with the diagnosis of MCDK who had been followed up by the nephrology outpatient clinic between 2002 and 2009 were invited to participate in the study. Twenty-six healthy children were investigated as a control group for microalbumin/creatinine ratio (µg/g creatinine). The mean age at diagnosis, the duration of follow-up, accompanying urinary tract abnormalities, attacks of urinary tract infection (UTI), contralateral kidney size, …
Tularemia As A Result Of Outdoor Activities For Children In The Countryside, Şaban Gürcan, Gamze Varol Saraçoğlu, Aynur Karadeni̇zli̇, Emi̇ne Neşe Özkayin, Şemsi̇ Zafer Öztürk, Cemal Çi̇çek, Bi̇nay Vatansever
Tularemia As A Result Of Outdoor Activities For Children In The Countryside, Şaban Gürcan, Gamze Varol Saraçoğlu, Aynur Karadeni̇zli̇, Emi̇ne Neşe Özkayin, Şemsi̇ Zafer Öztürk, Cemal Çi̇çek, Bi̇nay Vatansever
Turkish Journal of Medical Sciences
To investigate the features of a new tularemia outbreak that occurred in the Thrace region. Materials and methods: The research team visited the village after the identification of the index case. Serum and throat samples were taken from 41 villagers who were examined, and environmental samples were taken in order to identify the source of the outbreak. Culture, serology, and molecular methods were used to search for Francisella tularensis in these samples. Results: A total of 8 children were diagnosed with tularemia. The adults and all of the other children were seronegative for tularemia. All of the patients had a …
Salter Innominate Osteotomy Or Pemberton Pericapsular Osteotomy In Treatment Of Developmental Dysplasia Of Hip, Naci̇ Ezi̇rmi̇k, Kadri̇ Yildiz
Salter Innominate Osteotomy Or Pemberton Pericapsular Osteotomy In Treatment Of Developmental Dysplasia Of Hip, Naci̇ Ezi̇rmi̇k, Kadri̇ Yildiz
Turkish Journal of Medical Sciences
We aimed to compare the clinical and radiological results of the Salter innominate osteotomy (SIO) and Pemberton pericapsular osteotomy (PPO) in children with bilateral developmental hip dysplasia who had undergone PPO for 1 side and SIO for the other side in a 1-stage operation. Materials and methods: Children with bilateral hip dysplasia who had undergone PPO for 1 side and SIO for the other side in a 1-stage operation were included in this study, and 126 hips of 63 patients were evaluated. Clinical and radiological results were evaluated and compared using the Sutherland Pain Scale, Modified McKay Grading System, and …
Efficacy Of Azithromycin For Prevention Of Bronchopulmonary Dysplasia (Bpd), Manizheh Mostafa Gharehbaghi, Ali Peirovifar, Mortaza Ghojazadeh, Majid Mahallei
Efficacy Of Azithromycin For Prevention Of Bronchopulmonary Dysplasia (Bpd), Manizheh Mostafa Gharehbaghi, Ali Peirovifar, Mortaza Ghojazadeh, Majid Mahallei
Turkish Journal of Medical Sciences
Bronchopulmonary dysplasia (BPD) remains one of the most serious and challenging complications in premature infants. This study was conducted to evaluate the efficacy of azithromycin in the prevention of BPD in very low birth weight preterm infants Materials and methods: Preterm neonates with birth weight less than 1500 g were enrolled in a prospective randomized controlled clinical trial. One hundred eight neonates were randomly allocated to the intervention group (n = 56) or control group (n = 52). The intervention group received oral azithromycin 10 mg/kg for 1 week followed by 5 mg/kg for another week. The outcome measures were …
The Levels Of Serum Chemokines In Patients With Behçet's Disease, İbrahi̇m Kökçam, Di̇lara Turgut, Nafi̇ye Fulya İlhan, Demet Çi̇çek
The Levels Of Serum Chemokines In Patients With Behçet's Disease, İbrahi̇m Kökçam, Di̇lara Turgut, Nafi̇ye Fulya İlhan, Demet Çi̇çek
Turkish Journal of Medical Sciences
As chemokines are involved in the regulation of immune responses and inflammatory reactions, this study aimed to investigate the serum levels of some chemokines to determine whether they play roles in the pathogenesis of Behçet's disease (BD). Materials and methods: The study comprised 64 cases, allocated to active or inactive patient groups. The levels of serum macrophage inflammatory protein-1\alpha (MIP-1\alpha), epithelial neutrophil-activating protein-78 (ENA-78), and neutrophil-activating peptide-2 (NAP-2) were measured. Results: The serum levels of MIP-1\alpha and ENA-78 were statistically higher in BD patients than controls (P = 0.032 and P = 0.023, respectively). However, NAP-2 levels did not differ …
Comparison Of Conventional And Liquid-Based Cytology: Do The Diagnostic Benefits Outweigh The Financial Aspect?, Erdi̇n İlter, Ahmet Mi̇di̇, Berna Hali̇loğlu, Aygen Çeli̇k, Arzu Neşe Yener, İpek Ulu, Hayri̇ye Serpi̇l Bozkurt, Ümi̇t Özeki̇ci̇
Comparison Of Conventional And Liquid-Based Cytology: Do The Diagnostic Benefits Outweigh The Financial Aspect?, Erdi̇n İlter, Ahmet Mi̇di̇, Berna Hali̇loğlu, Aygen Çeli̇k, Arzu Neşe Yener, İpek Ulu, Hayri̇ye Serpi̇l Bozkurt, Ümi̇t Özeki̇ci̇
Turkish Journal of Medical Sciences
We aimed to compare the efficiency of conventional cytology (CC) and new liquid-based cytology (LBC) techniques in the assessment and the accuracy of Pap smears reported as abnormal by histological examinations. Materials and methods: A total of 3488 women who were undergoing routine cervical screening (1308 CC and 2180 LBC) were included in the initial screening. The results were assessed as either satisfactory or unsatisfactory. Satisfactory results were subdivided as negative, atypical squamous cells of undetermined significance (ASCUS), atypical squamous cells for which high-grade lesions could not be excluded (ASC-H), low-grade squamous intraepithelial lesion (LGSIL), high-grade squamous intraepithelial lesion (HGSIL), …
2-[18f]-Fluoro–2-Deoxy-D-Glucose Positron Emission Tomography In The Evaluation Of Breast Lesions And Axillary Involvement: A Comparison With Mammography And Histopathological Diagnosis, Oğuz Hançerli̇oğullari, Nuri̇ Arslan, Semi̇h Görgülü, Mehmet Fati̇h Can, Hani̇fe Asli Ayan Eke, Semra İnce, Erkan Öztürk, Ramazan Yildiz, Mehmet Ali̇ Özgüven
2-[18f]-Fluoro–2-Deoxy-D-Glucose Positron Emission Tomography In The Evaluation Of Breast Lesions And Axillary Involvement: A Comparison With Mammography And Histopathological Diagnosis, Oğuz Hançerli̇oğullari, Nuri̇ Arslan, Semi̇h Görgülü, Mehmet Fati̇h Can, Hani̇fe Asli Ayan Eke, Semra İnce, Erkan Öztürk, Ramazan Yildiz, Mehmet Ali̇ Özgüven
Turkish Journal of Medical Sciences
The objective of this prospective study was to evaluate the potential role of 2-[18f]-fluoro-2-deoxy-d-glucose (FDG) positron emission tomography (PET) in the differentiation of malignant and benign breast masses and the evaluation of axillary lymph node involvement. The secondary objective of this study was to assess the value of FDG PET in the initial staging of patients with breast cancer. Materials and methods: We evaluated 82 lesions in 79 consecutive patients (mean age of 54.4 ± 13.0; age range: 25-82 years) with FDG PET. While ultrasounds were performed in all cases, of the 79 patients, 72 had mammography and 58 had …
Comparison Of The Outcomes Of The Tot Technique Using A Hand-Made Tot Material And A Commercial One, Ahmet Tunç Özdemi̇r, Serkan Altinova, Haci İbrahi̇m Çi̇men, Ege Can Şerefoğlu, Hasbey Hakan Koyuncu, Mesut Gürdal
Comparison Of The Outcomes Of The Tot Technique Using A Hand-Made Tot Material And A Commercial One, Ahmet Tunç Özdemi̇r, Serkan Altinova, Haci İbrahi̇m Çi̇men, Ege Can Şerefoğlu, Hasbey Hakan Koyuncu, Mesut Gürdal
Turkish Journal of Medical Sciences
The purpose of this study was to compare the effectiveness of handmade transobturator tape (TOT) devices (tailored polypropylene mesh by the surgeon during the operation) with commercially available ones. Materials and methods: We included 78 consecutive women with the complaint of pure stress urinary incontinence recalcitrant to lifestyle modifications, pelvic floor muscle training, and medical treatment. The patients underwent TOT procedures either with a commercially available product (I-Stop, CL Medical, Lyon, France) (group 1) or with a device prepared during the operation with polypropylene mesh of 35 × 2 cm in size (Prolen®, Ethicon Inc., Somerville, New Jersey, USA) (group …
The Effect Of Palonosetron On Postoperative Nausea And Vomiting In Supratentorial Craniotomy Patients, Hali̇t Madenoğlu, Ci̇han Akdemi̇r, Recep Aksu, Ci̇hangi̇r Bi̇çer, Ayşe Ülgey, Adem Boyaci
The Effect Of Palonosetron On Postoperative Nausea And Vomiting In Supratentorial Craniotomy Patients, Hali̇t Madenoğlu, Ci̇han Akdemi̇r, Recep Aksu, Ci̇hangi̇r Bi̇çer, Ayşe Ülgey, Adem Boyaci
Turkish Journal of Medical Sciences
Postoperative nausea and vomiting (PONV) is a condition that adversely affects postoperative patient comfort. Supratentorial craniotomy patients were therefore monitored to establish the therapeutic efficiency of 2 different doses of palonosetron. Materials and methods: Patients scheduled for elective supratentorial craniotomy were randomly assigned to 3 groups: a control group (n = 30), a 0.05 mg palonosetron group (n = 30), and a 0.075 mg palonosetron group (n = 30). The drugs were given intravenously at the commencement of dura mater closure. Anesthesia maintenance was provided with 1 MAC sevoflurane in a 50% air and O_2 mixture. After the extubation, the …
Concomitant Carotid Endarterectomy And Off-Pump Coronary Artery Bypass Grafting In Coexistent Carotid And Coronary Artery Diseases, Murat Kurtoğlu, Mehmet Şanser Ateş, İbrahi̇m Duvan, Burak Emre Onuk, Yahya Hali̇dun Karagöz
Concomitant Carotid Endarterectomy And Off-Pump Coronary Artery Bypass Grafting In Coexistent Carotid And Coronary Artery Diseases, Murat Kurtoğlu, Mehmet Şanser Ateş, İbrahi̇m Duvan, Burak Emre Onuk, Yahya Hali̇dun Karagöz
Turkish Journal of Medical Sciences
To analyze the results of our experience with a combined procedure via off-pump coronary artery bypass (OPCABG) and carotid endarterectomy (CEA) retrospectively. Materials and methods: Eighty-four patients underwent OPCABG and CEA concomitantly between 1998 and 2011. Thirty (35.7%) patients had a cardiac history of myocardial infarction (MI), 13 (15.6%) had unstable angina (USAP), and 27 (32.1%) had USAP together with MI, whereas 14 (16.6%) were asymptomatic. Forty-two (50%) patients showed no neurological symptoms, 20 (23.8%) had transient ischemic attacks (TIAs), 21 (25%) suffered from stroke, and 1 (1.2%) experienced both. CEA was performed before OPCABG in all of the patients. …
Dietary Boron Intake Does Not Change The Ischemic Tolerance And Preconditioning Response In Isoproterenol-Induced Myocardial Injury In Healthy Rats, Mehmet Fati̇h Karakaş, Mustafa Kurt, Uğur Arslantaş, Göktürk İpek, Esra Karakaş, Emi̇ne Bi̇len, Hüsametti̇n Erdamar
Dietary Boron Intake Does Not Change The Ischemic Tolerance And Preconditioning Response In Isoproterenol-Induced Myocardial Injury In Healthy Rats, Mehmet Fati̇h Karakaş, Mustafa Kurt, Uğur Arslantaş, Göktürk İpek, Esra Karakaş, Emi̇ne Bi̇len, Hüsametti̇n Erdamar
Turkish Journal of Medical Sciences
Boron is important for many enzymes, most of which also have a role in the ischemic tolerance of the myocardium. We aimed to evaluate the influence of dietary boron intake on ischemic tolerance in a rat model. Materials and methods: Rats were divided into 3 groups according to the ischemia protocol: Sham (S) (n = 20 total), ischemia only (Isc-only) (n = 40 total), and remote ischemic preconditioning + ischemia (RIPC+Isc) (n = 40 total) groups. These 3 groups were further divided into 4 according to the amount of daily dietary boron (
Evaluation Of The Treatment Results Of Laryngeal Carcinoma: Our Experience Over 10 Years, Erkan Karataş, Eli̇f Baysal, Cengi̇z Durucu, Teki̇n Bağlam, Yildirim Ahmet Bayazit, Muzaffer Kanlikama
Evaluation Of The Treatment Results Of Laryngeal Carcinoma: Our Experience Over 10 Years, Erkan Karataş, Eli̇f Baysal, Cengi̇z Durucu, Teki̇n Bağlam, Yildirim Ahmet Bayazit, Muzaffer Kanlikama
Turkish Journal of Medical Sciences
To retrospectively analyze the treatment results for laryngeal carcinoma and to find the impact of the clinical parameters on the survival of the patients. Materials and methods: The medical records of 150 consecutive patients, operated on for laryngeal squamous cell carcinoma between 1991 and 2009, were reviewed. Tumor localization, TNM stages, treatment modalities, radiotherapy, second primary tumors, and tumor recurrence were recorded, and the survival data were obtained. Results: Neck metastasis was rare (3.6%) in T1 and T2 glottic tumors, while there was a significant increase in the rate of N+ neck (35%) in T3 and T4 glottic tumors (P …
The Relative Frequency Of Odontogenic Tumors In The Black Sea Region Of Turkey: An Analysis Of 86 Cases, Fi̇gen Çi̇zmeci̇ Şenel, Ezher Hamza Dayisoylu, Şafak Ersöz, Nuray Yilmaz Altintaş, Emre Tosun, Cem Üngör, Fati̇h Taşkesen
The Relative Frequency Of Odontogenic Tumors In The Black Sea Region Of Turkey: An Analysis Of 86 Cases, Fi̇gen Çi̇zmeci̇ Şenel, Ezher Hamza Dayisoylu, Şafak Ersöz, Nuray Yilmaz Altintaş, Emre Tosun, Cem Üngör, Fati̇h Taşkesen
Turkish Journal of Medical Sciences
To determine the relative frequency and distribution of different types of odontogenic tumors in southeastern Europe, focusing on the Black Sea region of Turkey. Materials and methods: In total 1165 oromaxillofacial biopsy records were evaluated for histologic diagnosis of odontogenic tumors over a 7-year period from patients referred to the Department of Oral and Maxillofacial Surgery and Department of Pathology, Karadeniz Technical University, Faculty of Dentistry and Medicine, Trabzon, Turkey. Results: A total of 86 odontogenic tumors were reported. Malignant transformation only occurred in 6 cases (6.8%), while the others were benign (93.2%). Odontoma was the most common odontogenic tumor …
Investigation Of The Clinical And Hematological Significance Of The First Observed Hemoglobin Ernz Variant [Β123(H1) Thr>Asn] In The Turkish Population, Ramazan Güneşaçar, Muhammet Murat Çeli̇k, Oktay Hasan Öztürk, Mustafa Çeli̇k, Cemi̇l Tümer, Tanju Çeli̇k
Investigation Of The Clinical And Hematological Significance Of The First Observed Hemoglobin Ernz Variant [Β123(H1) Thr>Asn] In The Turkish Population, Ramazan Güneşaçar, Muhammet Murat Çeli̇k, Oktay Hasan Öztürk, Mustafa Çeli̇k, Cemi̇l Tümer, Tanju Çeli̇k
Turkish Journal of Medical Sciences
In this report, we aimed to investigate the clinical and hematological significance of the first observed hemoglobin Ernz variant in the Turkish population. Materials and methods: We identified the Hb Ernz variant in 3 nonrelated females (Probands 1, 2, and 3). Proband 1’s family was also included the study. Hematological data were obtained with an automated cell counter and routine methodology. The beta-globin gene was sequenced by automatic sequencing. Results: Proband 1 was detected as a combination of Hb Ernz/Hb S without any clinical symptoms. Her sister and brother had to be an Hb Ernz/Hb S combination. Her mother and …