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Articles 1 - 30 of 141
Full-Text Articles in Medicine and Health Sciences
Ischemia-Reperfusion Injury, Reactive Oxygenmetabolites, And The Surgeon, A.Özdemir Aktan, A. Süha Yalçin
Ischemia-Reperfusion Injury, Reactive Oxygenmetabolites, And The Surgeon, A.Özdemir Aktan, A. Süha Yalçin
Turkish Journal of Medical Sciences
No abstract provided.
The Effects Of Constant Darkness And Constantlight On The Pineal Gland And Thymusmorphology In The Rats, Nihal İçten, Filiz Karagöz, K. Ali Güneç
The Effects Of Constant Darkness And Constantlight On The Pineal Gland And Thymusmorphology In The Rats, Nihal İçten, Filiz Karagöz, K. Ali Güneç
Turkish Journal of Medical Sciences
It is known that periods of constant darkness and constant light cause stim-ulation and inhibition of melatonin secretion from the pineal gland. It is also suggested that neuroendocrine responses to environmental stimuli, such as light, can influence immune responses through the pineal gland. For these reasons, in this study the effects of the alterations in the photoperiod rhythm on the pineal gland and thymus morphology were experimentally investigated. 30 Swiss albino rats, aged 4 wk, were divided into 3 groups. Group I rats were kept in a dark room, group II in a room under a bright artificial light and …
An Investigation On Adherence Of Cryptococcusneoformans Serotypes (A, B, C And D) In Ratlung Cell Culture, Şinasi Taner Yildiran, Hüseyin Gün
An Investigation On Adherence Of Cryptococcusneoformans Serotypes (A, B, C And D) In Ratlung Cell Culture, Şinasi Taner Yildiran, Hüseyin Gün
Turkish Journal of Medical Sciences
Cryptococcus neoformans causes an opportunistic infection known as cryptococcosis principally in immunocompromised individuals. It is not clearly known whether the serotype of the infecting strain of Cryptococcus neoformans has its own properties related to its adherence to host tissues in disease process. Here, the adherence of each serotype (A, B, C, and D) was investigated using primary rat lung cell culture in a timedependent manner. After the confluent monolayer of primary rat lung cell culture was obtained, the adherence assay was performed. The mean binding index (Bl) value of serotype D was statistically significant(p0.05). These findings suggest that the adherence …
The Effects Of Vitamin E On Gastric Ulcers Andgastric Mucosal Barrier In Stress Induced Rats, Cihat Güzel, Doğan Kurt, Abdurrahman Sermet, Zeki Kanay, Orhan Denli̇, Fikri Canoruç
The Effects Of Vitamin E On Gastric Ulcers Andgastric Mucosal Barrier In Stress Induced Rats, Cihat Güzel, Doğan Kurt, Abdurrahman Sermet, Zeki Kanay, Orhan Denli̇, Fikri Canoruç
Turkish Journal of Medical Sciences
Effects of vitamin E on gastric ulcers gastric mucosal barrier were in-vestigated in cold + restraint stress (CRS) induced rats. In this study 21 males two month old Swiss Albino Rats were used. Stress treated rats significantly decreased mucus and phospholipid content of gastric mucosa (p
How Hyperosmolar Solutions (Glucose 30%) Mayprevent Stress Induced Ulcers In Rats, Mustafa Yandi, Nazim Ağaoğlu, Tevhide Sel, Nihat Mansur
How Hyperosmolar Solutions (Glucose 30%) Mayprevent Stress Induced Ulcers In Rats, Mustafa Yandi, Nazim Ağaoğlu, Tevhide Sel, Nihat Mansur
Turkish Journal of Medical Sciences
It is accepted that administration of hyperosmolar solutions (glucose 30%) prevent stress-induced ulcers in the rats; but their mechanisms of action are not elucidated. In this study, we have investigated whether glucose is absorbed or not through the gastric wall. C14 labelled glucose solution of 30% was given to groups A (n=6), and B (n=8) and physiologic serum to group C(n=7). Restriction of movement with cold application was performed in group B and C. Ulcer indexes were 0.56±0.12 in group A, 0.83±0.27 in group B and 1.63±0.43 in group C. Net absorption rates were 12.2±4.8 %, 23.01±8.3 % and 53.1±4.65 …
The Role Of Vasopressin In Reduced Renalmass-Saline Hypertension, Besim Özaykan, Ayşe Doğan
The Role Of Vasopressin In Reduced Renalmass-Saline Hypertension, Besim Özaykan, Ayşe Doğan
Turkish Journal of Medical Sciences
The cause of reduced renal mass (RRM)-saline hypertension is not clear. In our study, it was aimed to investigate the role of vasopressin (AVP) in this type of hypertension by using selective V 1 antagonist of AVP. RRM was performed in 32 normotensive male Wistar rats under anesthesia in which we used a mixture of ketamine (130 mg/kg, i.m.) and chlorpromazine (1.3 mg/kg, i.m.). After a one-week of recovery period, all of the rats were given a low sodium diet and either distilled water (group 1) or 1% NaCl (group 2) as drinking water for 4 weeks. Five weeks after …
The Effects Of Phenoxybenzamine On Tyrosinehydroxylase (Th) And Th Mrna Level In Adrenalmedulla Of Sprague Dawley Rats, Muhittin Yürekli̇
The Effects Of Phenoxybenzamine On Tyrosinehydroxylase (Th) And Th Mrna Level In Adrenalmedulla Of Sprague Dawley Rats, Muhittin Yürekli̇
Turkish Journal of Medical Sciences
The effects of anti-hipertensive phenoxybenzamine were in-vestigated on tyrosine hydroxylase (TH) enzyme activity and TH mRNA levels. In the present study 5 months male sprague dawley (SD) rats were used. Phenoxybenzamine was injected i.p as 20 mg/kg which prepared in the 0.9 % NaCl and 5% ethanole. TH activity was measured by detecting of formation of 3 H 2 O as a formation of dopa from 3 H-tyrosine by radioisotope technique total adrenal RNA was isolated and hybridized wit 32 P labeled cDNA. TH mRNA was assayed by densitometric scanning of the autoradiograms using a densitometer. TH activity and TH …
Laminar Distribution Of The Sources Ofascending Spino-Supraspinal Pathways Involvedin Nociceptive Transmission And Pain Modulation, Figen Gövsa, Gülgün Kayalioğlu, Berrin Erdem, Vladimir A. Maisky, Nuran Hariri
Laminar Distribution Of The Sources Ofascending Spino-Supraspinal Pathways Involvedin Nociceptive Transmission And Pain Modulation, Figen Gövsa, Gülgün Kayalioğlu, Berrin Erdem, Vladimir A. Maisky, Nuran Hariri
Turkish Journal of Medical Sciences
In the present study, we made an attempt to detect more exactly the laminar distribution of spinomesencephalic, spinothalamic and spinotelencephalic tract neurons and to estimate the character of axonal collateralization in these spinosupraspinal pathways in the rat by means of retrograde double-labelling of cells with Fluoro-Gold (FG) and Primuline O (Pr). We found that sources of spino-supraspinal pathways to the upper centers of the brain stem, nucleus accumbens and septal nuclei were mixed together in the marginal zone, deep dorsal horn, reticulated area, lamina X and the lateral spinal nucleus, but have as a rule their own discrete projection fields. …
The Effect Of Pre-And Postnatal Cd Exposure Onconduction Velocity In Sciatic Nerve, Piraye Yargiçoğlu, Aysel Ağar, Ümit Kemal Şentürk, Nimet İzgüt Uysal, Derya Kiliç
The Effect Of Pre-And Postnatal Cd Exposure Onconduction Velocity In Sciatic Nerve, Piraye Yargiçoğlu, Aysel Ağar, Ümit Kemal Şentürk, Nimet İzgüt Uysal, Derya Kiliç
Turkish Journal of Medical Sciences
The purpose of the study has been to investigate the effect of preand postnatal Cd exposure on conduction velocity of sciatic nerve. Pregnant Swiss albino rats were divided into three groups as control (C), cadmium (Cd) and non-cadmium (NCd) groups. Control animals received tap water while rats in Cd group received Cd as CdCl 2 in their drinking water during the experimental period. The mothers of the NCd group were given Cd during their pregnancy but given tap water after birth. Twenty-two days after birth (postnatal day 22) the rats were separated from the mothers. The present study was performed …
Anatomy Of The Lateral Ankle Ligaments, Muzaffer Si̇ndel, Sevgi Demi̇r, Aydın Yildirim, Yaşar Uçar
Anatomy Of The Lateral Ankle Ligaments, Muzaffer Si̇ndel, Sevgi Demi̇r, Aydın Yildirim, Yaşar Uçar
Turkish Journal of Medical Sciences
The lateral ligaments of talocrural articulation, namely anterior talofibular ligament, posterior talofibular ligament and cal-caneofibular ligament, are important in an-atomic reconstruction. If reconstructed improperly, they are known to limit the movements of talocrural articulation and subtalar articulation (talocalcaneal articulation) Studies on anatomy of anterior talofibular ligament, posterior talofibular ligament and calcaneofibular ligament known as the lateral ligaments have some discrepancies. Knowing the importance of a more detailed discription of ankle ligament anatomy for reconstructing and fixing the ligaments, we studied 24 ankles and examined the width, length, attachment points of all three ligaments and their relationships with talocrural joint and …
The Validity Of Mahmood Scoring System Inmeningiomas, Sülen Sarioglu, M Serefettin Canda, Tülay Canda, Fulya Çakalağaoğlu, Nagihan Yalçin
The Validity Of Mahmood Scoring System Inmeningiomas, Sülen Sarioglu, M Serefettin Canda, Tülay Canda, Fulya Çakalağaoğlu, Nagihan Yalçin
Turkish Journal of Medical Sciences
Meningiomas are well known for their diverse histological apperance. Although generally considered benign, their behaviour is unpredictable and characterized by frequent recurrences. Histopathological features associated with aggressive behaviour have been described, but even the World Health Organization (WHO) grading system provides broad criteria for malignancy. Mahmood et al. described a scoring system, based on 6 histopathological features, establishing objective criteria. In this study, 73 specimens from 61 cases which were diagnosed as meningioma have been reviewed and scored by the criteria described by Mahmood et al. in order to search for the availability of the application of the system. Out …
Providencia Ssp In Nosocomial Urinary Infections, Efsun Akbaş, Orhan Cem Aktepe, Belkıs Levent, İbrahim Dalkilinç, Engin Güvener
Providencia Ssp In Nosocomial Urinary Infections, Efsun Akbaş, Orhan Cem Aktepe, Belkıs Levent, İbrahim Dalkilinç, Engin Güvener
Turkish Journal of Medical Sciences
This study was carried out in the Ankara Rehabilitation Centre over an eight month period. A total of 428 urine samples was collected from inpatients with long-term catheterization for diagnosis of bacteriuria. Urinary tract infection was detected in three hundreds and thirty-one samples. Escherichia coli was found to be the highest causative agent. Moreover in forty of these samples Providencia spp were determined as the fifth highest causative agent. This Providencia spp finding is important as it is the highest recorded in Turkey. Although six out of 40 isolates were during preservation, the remaining thirty-four isolates were further investigated to …
Blood Lactate/Pyruvate As A Predictor Of Shockdevelopment In Acute Myocardial Infarction, Arzu Seven, Sabiha Ci̇velek, Figen Kocaman, Lale Koldaş, Gülden Candan
Blood Lactate/Pyruvate As A Predictor Of Shockdevelopment In Acute Myocardial Infarction, Arzu Seven, Sabiha Ci̇velek, Figen Kocaman, Lale Koldaş, Gülden Candan
Turkish Journal of Medical Sciences
This study, designed to investigate the blood lactate and pyruvate levels in AMI, was carried out on 41 patients. Based upon the localization of AMI, the patients were studied under anterior AMI (n=17), anteroseptal AMI (n=9) and inferior AMI (n=15) groups. Left ventricular failure developed in five patients with anterior AMI and in one patient with anteroseptal AMI. Cardiogenic shock developed in two patients with anterior AMI. Lactate and pyruvate were analysed in the blood samples drawn 24-48 hours after AMI. CPK, CPK-MB, AST and LDH activities were determined in the sera of blood samples drawn within 6-24 hours of …
Urinary N-Acetyl-\Beta-D-Glucosaminidase Excretionin Asphyctic Newborns-Does It Predict Thedevelopment Of Acute Renal Failure?, Mete Aki̇sü, Nilgün Kültürsay, Resmiye Oral, Nermin Tansuğ, Caner Kabasakal
Urinary N-Acetyl-\Beta-D-Glucosaminidase Excretionin Asphyctic Newborns-Does It Predict Thedevelopment Of Acute Renal Failure?, Mete Aki̇sü, Nilgün Kültürsay, Resmiye Oral, Nermin Tansuğ, Caner Kabasakal
Turkish Journal of Medical Sciences
Urinary N-acetyl-\beta-D-glucosaminidase (NAG) levels of twenty healthy full-term newborns and of seventeen full-term newborns with perinatal asphyxia were evaluated within the first 48 hours of life. Urinary NAG levels and NAG indices (urinary NAG/urinary creatinine ratio) were sig-nificantly higher in newborns with perinatal asphyxia than control group (p
The Change Of Glutathione Dependentanti-Oxidant Mechanism In Patients With Chronicrenal Disease By Hemodialysis, Hatice Paşaoğlu, Sabahattin Muhtaroğlu, Mehmet Güneş, Cengiz Utaş
The Change Of Glutathione Dependentanti-Oxidant Mechanism In Patients With Chronicrenal Disease By Hemodialysis, Hatice Paşaoğlu, Sabahattin Muhtaroğlu, Mehmet Güneş, Cengiz Utaş
Turkish Journal of Medical Sciences
In order to test the for existence of a possible effect during hemodialysis we investigated glutathione and related enzymes before and after dialysis of 36 patients (20 M/16 F) with chronic renal failure (CRF). 25 healthy person (15 M/10F) served as controls. Erythrocyte reduced glutathione (GSH) concentrations, glucose -6- phosphate dehydrogenase (G-6-PD), glutathione peroxidase (GPX) activities and plasma GPX activities were significantly decreased in patients (p
Sensory Conduction Along The Fourth Finger Inpatients With Carpal Tunnel Syndrome, H. Özden Şener, Nezih Yücemen, Nermin Mutluer
Sensory Conduction Along The Fourth Finger Inpatients With Carpal Tunnel Syndrome, H. Özden Şener, Nezih Yücemen, Nermin Mutluer
Turkish Journal of Medical Sciences
The aim of this study was to examine the value of sensory conduction along the median and ulnar nerves of the fourth finger in the diagnosis of carpal tunnel syndrome. 20 females with carpal tunnel syndrome as diagnosed by clinical and routine electrophysiological examinations were included in the study. By using the near-nerve technique, orthodromic sensory conduction along the thumb, 3rd, and 4th fingers for median; and 4th and 5th fingers for ulnar nerve study was performed. 't test' was used for statistical analysis In 19 of 20 patients with carpal tunnel syndrome, the conduction velcocity was reduced along the …
Prevalence Of Rheumatoid Factor (Rf) Andanti-Native-Dna Antibodies (Anti-N Dna) Indifferent Age Subpopulations, Fatoş Önen, Cansel Türkay, Ali Meydan, H. Sebila Dökmetaş, Haldun Sümer, Lütfi Hocaoğlu, Serhat Içagasioğlu, M. Zahir Bakici
Prevalence Of Rheumatoid Factor (Rf) Andanti-Native-Dna Antibodies (Anti-N Dna) Indifferent Age Subpopulations, Fatoş Önen, Cansel Türkay, Ali Meydan, H. Sebila Dökmetaş, Haldun Sümer, Lütfi Hocaoğlu, Serhat Içagasioğlu, M. Zahir Bakici
Turkish Journal of Medical Sciences
In this study, we have evaluated the prevalence of RF and anti-n-DNA in dif-ferent age subpopulations grouped according to their clinical status. RF and anti-n-DNA were measured in the serum of 51 elderly people considered to be successfully aging (group 1), 65 chronically ill elderly (group 2), 65 chronically ill patients under 65 years (group 3) and 30 patients with rheumatoid arthritis (group 4). The results were compared to 100 healthy persons as a control group under 65 years. The prevalences of RF in group 1, group 2 and group 3 were significantly higher than the healthy younger controls. Particularly …
Value Of Anti-Kp 90 Lmmunoglobulin A (Lga)Antibodies In Diagnosis Of Active Tuberculosis: Apreliminary Report, Sevtap Arikan, Serdar Tuncer, Dürdal Us, Serhat Ünal, Şemsettin Ustaçelebi̇
Value Of Anti-Kp 90 Lmmunoglobulin A (Lga)Antibodies In Diagnosis Of Active Tuberculosis: Apreliminary Report, Sevtap Arikan, Serdar Tuncer, Dürdal Us, Serhat Ünal, Şemsettin Ustaçelebi̇
Turkish Journal of Medical Sciences
The lack of a rapid and reliable method for diagnosis of active tuberculosis necessitated the development of new laboratory techniques. Diagnostic value of a re-cently developed ELISA for the detection of lgA antibodies to Kp 90 antigen of Mycobacterium tuberculosis was evaluated in this study and the results were compared with the conventional methods and polymerase chain reaction (PCR). Fifty six sera and body fluid (pleural, peritoneal, pericardial) samples from 23 patients with ac-tive tuberculosis and 26 control subjects were included in the study. Out of 28 samples obtained from the patients, 22 (79%) yielded positive result for lgA. Comparison …
The Frequency Of Chromosomal Abnormalities Inmen With Azoospermia Andoligoasthenoteratozoospermia: A Preliminarystudy, Cüneyt Tüzün, Kubilay Vi̇cdan, Semra Kahraman, Suat Özgür, Ahmet Z. Işik, Kutay Bi̇beroğlu
The Frequency Of Chromosomal Abnormalities Inmen With Azoospermia Andoligoasthenoteratozoospermia: A Preliminarystudy, Cüneyt Tüzün, Kubilay Vi̇cdan, Semra Kahraman, Suat Özgür, Ahmet Z. Işik, Kutay Bi̇beroğlu
Turkish Journal of Medical Sciences
The aim of this study is to investigate the frequency of chromosomal abnormalities in men with severe andrological infertility, In 50 men with azoospermia and severe oligoasthenoteratozoospermia (OAT), who referred for our intracytoplasmic sperm injection program, a cytogenetic study has been prospectively carried out. Peripheral blood lymphocytes were cultured for chromosomal analysis and for each proband 30 metaphases were analyzed by GTG banding technique. Major chromosomal abnormalities were detected in 4 of cases (8%). There were 3 sex-chromosome abnormalities, 46XXY in all 3 cases, and one autosomal chromosomal abnormality 46 XY, t (1;7) (P32;Q32). Although the sample size is small, …
Detection Of Antinuclear Antibody (Ana) Inpatients With Mycoplasmal Pneumonia, Sevtap Arikan, Sibel Ergüven, Şemsettin Ustaçelebi̇
Detection Of Antinuclear Antibody (Ana) Inpatients With Mycoplasmal Pneumonia, Sevtap Arikan, Sibel Ergüven, Şemsettin Ustaçelebi̇
Turkish Journal of Medical Sciences
No abstract provided.
Hepatoerythropoietic Porphyria And Cerebralabnormalities, Mehmet Helvaci, Buket Özkaya, Işın Yaprak, Üstün Ezer
Hepatoerythropoietic Porphyria And Cerebralabnormalities, Mehmet Helvaci, Buket Özkaya, Işın Yaprak, Üstün Ezer
Turkish Journal of Medical Sciences
No abstract provided.
Factor Vii Deficiency Presenting Withmenometrorrhagia, Gürden Gür, Mete Özdoğan, Orhan Özgür, Sedat Boyacioğlu, Hasan Telatar
Factor Vii Deficiency Presenting Withmenometrorrhagia, Gürden Gür, Mete Özdoğan, Orhan Özgür, Sedat Boyacioğlu, Hasan Telatar
Turkish Journal of Medical Sciences
No abstract provided.
A Case Of Trisomy 8 Mosaicism, Sadık Akşi̇t, Meral Türker, Işın Yaprak, Suat Çağlayan, Coskun Dorak, Savaş Kansoy
A Case Of Trisomy 8 Mosaicism, Sadık Akşi̇t, Meral Türker, Işın Yaprak, Suat Çağlayan, Coskun Dorak, Savaş Kansoy
Turkish Journal of Medical Sciences
No abstract provided.
Patients' Rights In Turkey, Şükrü Hatun
Patients' Rights In Turkey, Şükrü Hatun
Turkish Journal of Medical Sciences
Patient's rights primarily mean the practice of human rights and values in the field of health care services and include the rights which are considered as third generation rights. Recently, in many countries, especially in European countries, concept of health care services which give importance to patients' rights has been developed. Patients' rights in Turkey is one of the least known issues and remembered only by physicians' malparactises causing death or disabilities some of which are speculative. Efforts are needed to strengthen the patients' rights should be accelerated in order to protect the patients and physicians from unnecessary speculations in …
Effects Of The N-Ras Oncogene On The Expression Of Other Cellular Genes In Co25 Myoblast Cells, Hülya Zeyti̇noğlu, Ian Gibson
Effects Of The N-Ras Oncogene On The Expression Of Other Cellular Genes In Co25 Myoblast Cells, Hülya Zeyti̇noğlu, Ian Gibson
Turkish Journal of Medical Sciences
The effects of the N- ras oncogene on the transcription levels of c- myc, p53, c-K-ras and b-actin genes have been investigated by Northern blotting in a cell line which normally differentiates into myotubes. Treatment of cells with dexamethasone activates N- ras gene, then cells proliferate and form foci. The transcription level of c- myc gene was generally high during transformation whereas c-K- ras mRNAs levels were high during differentiation. Following induction of the N- ras oncogene, the level of c-myc mRNA first decreased in two days and then increased in three and four days. During differentiation, c-K- ras mRNA …
Hüseyin Eray Bulut,Erdoğan Gürsoy, An Ultrastructural Study
Hüseyin Eray Bulut,Erdoğan Gürsoy, An Ultrastructural Study
Turkish Journal of Medical Sciences
Cryptorchidism causes a failure in testosterone secretion from the testicles. The metabolism of the adrenocortical steroids is influenced by sex hormones. Therefore testicular failure may cause structural and func-tional alterations in adrenal cortex. It is the aim of the present study to evaluate the effect of experimental caryptorchidism on the ultrastructure of the rat adrenal cortex, especialy on the reticularis region during prepubertal and postpubertal ages. Three groups of animals were used in the present study. The first (prepubertal) group consisted of 5,21-day old rats whereas the second (postpubertal) group was made of 5,3-month old rats. Third group was the …
The Effects Of Vitamin E On Catalase Activies In Various Rat Tissues, Gülinnaz Alper, Mehtap Çinar, Cenk Can, Gülriz Menteş, Biltan Ersöz, Akgün Evinç
The Effects Of Vitamin E On Catalase Activies In Various Rat Tissues, Gülinnaz Alper, Mehtap Çinar, Cenk Can, Gülriz Menteş, Biltan Ersöz, Akgün Evinç
Turkish Journal of Medical Sciences
Vitamin E and other antioxidants prevent or minimize oxidative damage in biological systems. The level of antioxidant defense sufficient to protect the organism from high free radical concentrations is one of the new horizons for Vitamin E research. The role of Vitamin E as a protective agent aganist oxidative stress was evaluated by meas-uring the antioxidant enzyme catalase (CAT) activities in different tissues of Swiss male albino rats aged two months. In this study, rats were divided to three groups; control (n=10), E 1 (n=5) which received 25 mg/kg. per day of Vitamin E, IM. for 10 days and E …
Effects Of Acute Hypothyroidism On Brainstemauditory Evoked Potentials (Baeps), Metin Özata, Abdullah Özkardeş, M. Ali Gündoğan
Effects Of Acute Hypothyroidism On Brainstemauditory Evoked Potentials (Baeps), Metin Özata, Abdullah Özkardeş, M. Ali Gündoğan
Turkish Journal of Medical Sciences
Although functional alterations in the central nervous system (CNS) and peripheral nerves are well documented in overt hypothyroidism, little is known about alterations of CNS in acute hypothyroidism. Sixteen patients with differentiated thyroid carcinoma were studied when prepared for radioiodine scanning after stopping levothyroxine (LT 4 ) therapy for 6 weeks to determine whether acute hypothyroidism leads to alteration in brainstem auditory evoked potentials (BAEPs). Repeat BAEPs were performed on the same patients at 6 months of the following L-T 4 therapy when patients were eu-thyroid. Neurophysiological findings were compared with a group of 20 normal controls with no hystory …
Visual Evoked Potentials In Diabetic Patients, Ömer Azal, Abdullah Özkardeş, M. Emin Önde, Metin Özata, Gökhan Özişik, Ahmet Çorakçi, M. Ali Gündoğan
Visual Evoked Potentials In Diabetic Patients, Ömer Azal, Abdullah Özkardeş, M. Emin Önde, Metin Özata, Gökhan Özişik, Ahmet Çorakçi, M. Ali Gündoğan
Turkish Journal of Medical Sciences
Currently there are conflicting results regarding optic neuropathy in diabetes mellitus. Therefore, the aim of the present study was to evaluate optic neuropathy in diabetic patients. We studied visual evoked potentials (VEPs) in 20 diabetic patients (6 insulin dependent, 14 noninsulin dependent; 8 women, 12 men; mean age: 49.70± 18.22 years; mean duration of diabetes: 9.33 ± 5.75 years) and 20 age-, and sex-matched healthy subjects (7 women, 13 men; mean age: 52.40 ± 16.02 years) as a control group. Nine of 20 diabetic patients had sensorimotor neuropathy, and 5 diabetic patients had both sensorimotor neuropathy and autonomic neuropathy, as …
Alterations Of Erythrocyte And Plasma Lipid Peroxides As Well As Antioxidant Mechanism In Patients With Type Ii Diabetes Mellitus (Niddm), Yıldız Atamer, Yüksel Koçyi̇ği̇t, Aytaç Atamer, Nuriye Mete, Naime Canoruç, Gülten Toprak
Alterations Of Erythrocyte And Plasma Lipid Peroxides As Well As Antioxidant Mechanism In Patients With Type Ii Diabetes Mellitus (Niddm), Yıldız Atamer, Yüksel Koçyi̇ği̇t, Aytaç Atamer, Nuriye Mete, Naime Canoruç, Gülten Toprak
Turkish Journal of Medical Sciences
It has been maintained that free oxygen radicals (FOR) that occur in cell have important roles in the ethiopathogenesis of diabet, and that cell damage progressing as a result of their accumulation is responsible for the development of diabetic complications. In recent years, along with free oxygen radicals, antioxidant mechanisms and the substances influencing as free radical cleaner have been investigated in connection with diabet. With this respect, in a total of 30 patients with type II Diabetes Mellitus (NIDDM), 15 with diabetic retinopathy and 15 without diabetic retinopathy, and in 20 healthy subjects, we measured glutathione (GSH), catalase and …