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Articles 91 - 120 of 2396
Full-Text Articles in Medicine and Health Sciences
Pharmacological Treatment Of Hyperactive Delirium In People With Covid-19: Rethinking Conventional Approaches, G. Ostuzzi, C. Gastaldon, D. Papola, A. Fagiolini, S. Dursun, D. Taylor, C. U. Correll, C. Barbui
Pharmacological Treatment Of Hyperactive Delirium In People With Covid-19: Rethinking Conventional Approaches, G. Ostuzzi, C. Gastaldon, D. Papola, A. Fagiolini, S. Dursun, D. Taylor, C. U. Correll, C. Barbui
Journal Articles
No abstract provided.
Pregnancy And Neonatal Outcomes In Sars-Cov-2 Infection: A Systematic Review., R. S. Chamseddine, F. Wahbeh, F. Chervenak, L. J. Salomon, B. Ahmed, A. Rafii
Pregnancy And Neonatal Outcomes In Sars-Cov-2 Infection: A Systematic Review., R. S. Chamseddine, F. Wahbeh, F. Chervenak, L. J. Salomon, B. Ahmed, A. Rafii
Journal Articles
With the emergence of SARS-CoV-2 and its rapid spread, concerns regarding its effects on pregnancy outcomes have been growing. We reviewed 245 pregnancies complicated by maternal SARS-CoV-2 infection across 48 studies listed on PubMed and MedRxiv. The most common clinical presentations were fever (55.9%), cough (36.3%), fatigue (11.4%), and dyspnea (12.7%). Only 4.1% of patients developed respiratory distress. Of all patients, 89.0% delivered via cesarean section (n = 201), with a 33.3% rate of gestational complications, a 35.3% rate of preterm delivery, and a concerning 2.5% rate of stillbirth delivery or neonatal death. Among those tested, 6.45% of newborns were …
Response To Thrombotic Microangiopathy: Covid-19 Or Hydroxychloroquine?, R. Wanchoo, M. L. Barilla-Labarca, K. D. Jhaveri
Response To Thrombotic Microangiopathy: Covid-19 Or Hydroxychloroquine?, R. Wanchoo, M. L. Barilla-Labarca, K. D. Jhaveri
Journal Articles
No abstract provided.
The Management Of Venous Thromboembolism In Hospitalized Patients With Covid-19, A. C. Spyropoulos
The Management Of Venous Thromboembolism In Hospitalized Patients With Covid-19, A. C. Spyropoulos
Journal Articles
No abstract provided.
The Global Impact Of Covid-19 On Gastrointestinal Endoscopy Units: An International Survey Of Endoscopists, M. Alboraie, A. Piscoya, Q. T. Tran, R. B. Mendelsohn, A. S. Butt, L. Lenz, P. Alavinejad, M. H. Emara, S. Iqbal, S. Vignesh, +10 Additional Authors
The Global Impact Of Covid-19 On Gastrointestinal Endoscopy Units: An International Survey Of Endoscopists, M. Alboraie, A. Piscoya, Q. T. Tran, R. B. Mendelsohn, A. S. Butt, L. Lenz, P. Alavinejad, M. H. Emara, S. Iqbal, S. Vignesh, +10 Additional Authors
Journal Articles
© 2020 Pan-Arab Association of Gastroenterology Background & study aims: Corona virus disease-19 (COVID-19) pandemic has markedly impacted routine medical services including gastrointestinal (GI) endoscopy. We aim to report the real-life performance in high volume GI endoscopy units during the pandemic. Patients and methods: A web-based survey covering all aspects of daily performance in GI endoscopy units was sent to endoscopy units worldwide. Responses were collected and data were analyzed to reveal the effect of COVID-19 pandemic on endoscopy practice. Results: Participants from 48 countries (n = 163) responded to the survey with response rate of 67.35%. The majority (85%) …
Triaging Interventional Pain Procedures During Covid-19 Or Related Elective Surgery Restrictions: Evidence-Informed Guidance From The American Society Of Interventional Pain Physicians (Asipp), C. Gharibo, A. Sharma, A. Soin, S. Shah, S. Diwan, R. Buenaventura, D. E. Nampiaparampil, S. Aydin, S. Bakshi, K. Rajput, +13 Additional Authors
Triaging Interventional Pain Procedures During Covid-19 Or Related Elective Surgery Restrictions: Evidence-Informed Guidance From The American Society Of Interventional Pain Physicians (Asipp), C. Gharibo, A. Sharma, A. Soin, S. Shah, S. Diwan, R. Buenaventura, D. E. Nampiaparampil, S. Aydin, S. Bakshi, K. Rajput, +13 Additional Authors
Journal Articles
BACKGROUND: The COVID-19 pandemic has worsened the pain and suffering of chronic pain patients due to stoppage of "elective" interventional pain management and office visits across the United States. The reopening of America and restarting of interventional techniques and elective surgical procedures has started. Unfortunately, with resurgence in some states, restrictions are once again being imposed. In addition, even during the Phase II and III of reopening, chronic pain patients and interventional pain physicians have faced difficulties because of the priority selection of elective surgical procedures.Chronic pain patients require high intensity care, specifically during a pandemic such as COVID-19. Consequently, …
Unique Case Of Central Retinal Artery Occlusion Secondary To Covid-19 Disease, S. Acharya, M. Diamond, S. Anwar, A. Glaser, P. Tyagi
Unique Case Of Central Retinal Artery Occlusion Secondary To Covid-19 Disease, S. Acharya, M. Diamond, S. Anwar, A. Glaser, P. Tyagi
Journal Articles
© 2020 The Authors SARS-COVID-2 has been noted to be associated with neurological symptoms and complications including stroke. Hypercoagulability associated with COVID-19 has been described as a “sepsis-induced coagulopathy” and may predispose to spectrum of thromboembolic events. We present a unique article of isolated central retinal artery occlusion secondary to SARS-COV 2.
Usefulness Of Elevated Troponin To Predict Death In Patients With Covid-19 And Myocardial Injury., D. T. Majure, L. Gruberg, S. G. Saba, C. Kvasnovsky, J. S. Hirsch, R. Jauhar, Northwell Health Covid-19 Research Consortium
Usefulness Of Elevated Troponin To Predict Death In Patients With Covid-19 And Myocardial Injury., D. T. Majure, L. Gruberg, S. G. Saba, C. Kvasnovsky, J. S. Hirsch, R. Jauhar, Northwell Health Covid-19 Research Consortium
Journal Articles
Elevations in troponin levels have been shown to predict mortality in patients with coronavirus disease 2019 (COVID-19). The role of inflammation in myocardial injury remains unclear. We sought to determine the association of elevated troponin with mortality in a large, ethnically diverse population of patients hospitalized with COVID-19, and to determine the association of elevated inflammatory markers with increased troponin levels. We reviewed all patients admitted at our health system with COVID-19 from March 1 to April 27, 2020, who had a troponin assessment within 48 hours of admission. We used logistic regression to calculate odds ratios (ORs) for mortality …
Interim Guidance For Basic And Advanced Life Support In Adults, Children, And Neonates With Suspected Or Confirmed Covid-19 From The Emergency Cardiovascular Care Committee And Get With The Guidelines-Resuscitation Adult And Pediatric Task Forces Of The American Heart Association, D. P. Edelson, C. Sasson, P. S. Chan, D. L. Atkins, K. Aziz, L. B. Becker, R. A. Berg, S. M. Bradley, S. C. Brooks, A. A. Topjian, +17 Additional Authors
Interim Guidance For Basic And Advanced Life Support In Adults, Children, And Neonates With Suspected Or Confirmed Covid-19 From The Emergency Cardiovascular Care Committee And Get With The Guidelines-Resuscitation Adult And Pediatric Task Forces Of The American Heart Association, D. P. Edelson, C. Sasson, P. S. Chan, D. L. Atkins, K. Aziz, L. B. Becker, R. A. Berg, S. M. Bradley, S. C. Brooks, A. A. Topjian, +17 Additional Authors
Journal Articles
No abstract provided.
Two-Needle Technique For Lumbar Radiofrequency Medial Branch Denervation: A Technical Note, K. B. Chapman, F. Schirripa, T. Oud, P. S. Groenen, R. R. Ramsook, N. Van Helmond
Two-Needle Technique For Lumbar Radiofrequency Medial Branch Denervation: A Technical Note, K. B. Chapman, F. Schirripa, T. Oud, P. S. Groenen, R. R. Ramsook, N. Van Helmond
Journal Articles
© 2020, American Society of Interventional Pain Physicians. All rights reserved. Background: Radiofrequency ablation (RFA) of the medial branches of the dorsal rami has been reported to relieve facet joint–related back pain for 6 months to 1 year in 60% of patients. Although providing benefit in a significant proportion of patients, there remains a group of patients who do not experience any pain relief from RFA or experience only benefit from the ablation for a short period. Failure of RFA has been attributed to technical failure of coagulating the nerve or coagulation of a minimal section of the nerve, allowing …
Cytokine Elevation In Severe And Critical Covid-19: A Rapid Systematic Review, Meta-Analysis, And Comparison With Other Inflammatory Syndromes., D. E. Leisman, L. Ronner, R. Pinotti, M. D. Taylor, P. Sinha, C. S. Calfee, A. V. Hirayama, F. Mastroiani, C. J. Turtle, C. S. Deutschman, +2 Additional Authors
Cytokine Elevation In Severe And Critical Covid-19: A Rapid Systematic Review, Meta-Analysis, And Comparison With Other Inflammatory Syndromes., D. E. Leisman, L. Ronner, R. Pinotti, M. D. Taylor, P. Sinha, C. S. Calfee, A. V. Hirayama, F. Mastroiani, C. J. Turtle, C. S. Deutschman, +2 Additional Authors
Journal Articles
The description of a so-called cytokine storm in patients with COVID-19 has prompted consideration of anti-cytokine therapies, particularly interleukin-6 antagonists. However, direct systematic comparisons of COVID-19 with other critical illnesses associated with elevated cytokine concentrations have not been reported. In this Rapid Review, we report the results of a systematic review and meta-analysis of COVID-19 studies published or posted as preprints between Nov 1, 2019, and April 14, 2020, in which interleukin-6 concentrations in patients with severe or critical disease were recorded. 25 COVID-19 studies (n=1245 patients) were ultimately included. Comparator groups included four trials each in sepsis (n=5320), cytokine …
Hrs/Ehra/Aphrs/Lahrs/Acc/Aha Worldwide Practice Update For Telehealth And Arrhythmia Monitoring During And After A Pandemic, N. Varma, N. F. Marrouche, L. Aguinaga, C. M. Albert, E. Arbelo, J. I. Choi, M. K. Chung, G. Conte, L. M. Epstein, P. D. Varosy, +13 Additional Authors
Hrs/Ehra/Aphrs/Lahrs/Acc/Aha Worldwide Practice Update For Telehealth And Arrhythmia Monitoring During And After A Pandemic, N. Varma, N. F. Marrouche, L. Aguinaga, C. M. Albert, E. Arbelo, J. I. Choi, M. K. Chung, G. Conte, L. M. Epstein, P. D. Varosy, +13 Additional Authors
Journal Articles
No abstract provided.
Interrupting Microaggressions In Health Care Settings: A Guide For Teaching Medical Students, R. G. Acholonu, T. E. Cook, R. O. Roswell, R. E. Greene
Interrupting Microaggressions In Health Care Settings: A Guide For Teaching Medical Students, R. G. Acholonu, T. E. Cook, R. O. Roswell, R. E. Greene
Journal Articles
© 2020 Acholonu et al. Introduction: Microaggressions are connected to broader conceptualizations of the impact of implicit bias and systems of inequity. The body of evidence supporting the need for more-open discussions in medical education about race, racism, and their impact on health disparities continues to grow. Some have advocated for the importance of bringing anti-racist pedagogy into medical education curricula, which involves explicitly attempting to move beyond people's comfort zones and acknowledging that discomfort can be a catalyst for growth. To discuss the intent and impact of microaggressions in health care settings and how we might go about responding …
Cryoballoon Ablation Of Pulmonary Veins For Persistent Atrial Fibrillation: Results From The Multicenter Stop Persistent Af Trial, W. W. Su, V. Y. Reddy, K. Bhasin, J. Champagne, R. M. Sangrigoli, K. M. Braegelmann, F. J. Kueffer, P. Novak, S. K. Gupta, H. Calkins, +1 Additional Author
Cryoballoon Ablation Of Pulmonary Veins For Persistent Atrial Fibrillation: Results From The Multicenter Stop Persistent Af Trial, W. W. Su, V. Y. Reddy, K. Bhasin, J. Champagne, R. M. Sangrigoli, K. M. Braegelmann, F. J. Kueffer, P. Novak, S. K. Gupta, H. Calkins, +1 Additional Author
Journal Articles
No abstract provided.
Gastrointestinal Endoscopy During The Coronavirus Pandemic In The New York Area: Results From A Multi-Institutional Survey., S. Mahadev, O. C. Aroniadis, L. H. Barraza, E. Agarunov, M. S. Smith, A. J. Goodman, P. C. Benias, J. M. Buscaglia, S. A. Gross, T. A. Gonda, +6 Additional Authors
Gastrointestinal Endoscopy During The Coronavirus Pandemic In The New York Area: Results From A Multi-Institutional Survey., S. Mahadev, O. C. Aroniadis, L. H. Barraza, E. Agarunov, M. S. Smith, A. J. Goodman, P. C. Benias, J. M. Buscaglia, S. A. Gross, T. A. Gonda, +6 Additional Authors
Journal Articles
Background and study aims The coronavirus disease 2019 (COVID-19), and measures taken to mitigate its impact, have profoundly affected the clinical care of gastroenterology patients and the work of endoscopy units. We aimed to describe the clinical care delivered by gastroenterologists and the type of procedures performed during the early to peak period of the pandemic. Methods Endoscopy leaders in the New York region were invited to participate in an electronic survey describing operations and clinical service. Surveys were distributed on April 7, 2020 and responses were collected over the following week. A follow-up survey was distributed on April 20, …
Home Dialysis In The Time Of Covid-19: Reflections On Rapidly Changing Policies., M. Sachdeva, K. D. Jhaveri, S. Fishbane
Home Dialysis In The Time Of Covid-19: Reflections On Rapidly Changing Policies., M. Sachdeva, K. D. Jhaveri, S. Fishbane
Journal Articles
No abstract provided.
Consensus Guidelines For Digital Scholarship In Academic Promotion, A. Husain, Z. Repanshek, M. Singh, F. Ankel, J. Beck-Esmay, D. Cabrera, T. M. Chan, R. Cooney, M. Gisondi, E. Brumfield, +8 Additional Authors
Consensus Guidelines For Digital Scholarship In Academic Promotion, A. Husain, Z. Repanshek, M. Singh, F. Ankel, J. Beck-Esmay, D. Cabrera, T. M. Chan, R. Cooney, M. Gisondi, E. Brumfield, +8 Additional Authors
Journal Articles
Copyright: © 2020 Husain et al. This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) License. See: http://creativecommons.org/licenses/by/4.0/ Introduction: As scholarship moves into the digital sphere, applicant and promotion and tenure (P&T) committee members lack formal guidance on evaluating the impact of digital scholarly work. The P&T process requires the appraisal of individual scholarly impact in comparison to scholars across institutions and disciplines. As dissemination methods evolve in the digital era, we must adapt traditional P&T processes to include emerging forms of digital scholarship. Methods: We conducted a blended, …
Incidence Of Myocardial Infarction And Cerebrovascular Accident In Patients With Hidradenitis Suppurativa, S. Reddy, A. Strunk, G. B. Jemec, A. Garg
Incidence Of Myocardial Infarction And Cerebrovascular Accident In Patients With Hidradenitis Suppurativa, S. Reddy, A. Strunk, G. B. Jemec, A. Garg
Journal Articles
No abstract provided.
Stories To Communicate Individual Risk For Opioid Prescriptions For Back And Kidney Stone Pain: Protocol For The Life Storried Multicenter Randomized Clinical Trial, Z. F. Meisel, E. B. Goldberg, A. R. Dolan, E. Bansal, K. V. Rhodes, E. P. Hess, C. C. Cannuscio, M. M. Schapira, J. Perrone, F. S. Shofer, +4 Additional Authors
Stories To Communicate Individual Risk For Opioid Prescriptions For Back And Kidney Stone Pain: Protocol For The Life Storried Multicenter Randomized Clinical Trial, Z. F. Meisel, E. B. Goldberg, A. R. Dolan, E. Bansal, K. V. Rhodes, E. P. Hess, C. C. Cannuscio, M. M. Schapira, J. Perrone, F. S. Shofer, +4 Additional Authors
Journal Articles
© 2020 JMIR Publications. All rights reserved. Background: Prescription opioid misuse in the United States is a devastating public health crisis; many chronic opioid users were originally prescribed this class of medication for acute pain. Video narrative-enhanced risk communication may improve patient outcomes, such as knowledge of opioid risk and opioid use behaviors after an episode of acute pain. Objective: Our objective is to assess the effect of probabilistic and narrative-enhanced opioid risk communication on patient-reported outcomes, including knowledge, opioid use, and patient preferences, for patients who present to emergency departments with back pain and kidney stone pain. Methods: This …
Quantitative Estimation Of Nerve Fiber Engagement By Vagus Nerve Stimulation Using Physiological Markers, Y. C. Chang, M. Cracchiolo, U. Ahmed, I. Mughrabi, A. Gabalski, L. Becker, T. Datta-Chaudhuri, Y. Al-Abed, T. P. Zanos, S. Zanos, +2 Additional Authors
Quantitative Estimation Of Nerve Fiber Engagement By Vagus Nerve Stimulation Using Physiological Markers, Y. C. Chang, M. Cracchiolo, U. Ahmed, I. Mughrabi, A. Gabalski, L. Becker, T. Datta-Chaudhuri, Y. Al-Abed, T. P. Zanos, S. Zanos, +2 Additional Authors
Journal Articles
© 2020 The Author(s) Background: Cervical vagus nerve stimulation (VNS) is an emerging bioelectronic treatment for brain, metabolic, cardiovascular and immune disorders. Its desired and off-target effects are mediated by different nerve fiber populations and knowledge of their engagement could guide calibration and monitoring of VNS therapies. Objective: Stimulus-evoked compound action potentials (eCAPs) directly provide fiber engagement information but are currently not feasible in humans. A method to estimate fiber engagement through common, noninvasive physiological readouts could be used in place of eCAP measurements. Methods: In anesthetized rats, we recorded eCAPs while registering acute physiological response markers to VNS: cervical …
The New York City Pandemic Resuscitation Equitable Allocation Principles, K. V. Rhodes, E. K. Wei, R. J. Salway, S. Natsui, D. Silvestri, C. K. Cassel
The New York City Pandemic Resuscitation Equitable Allocation Principles, K. V. Rhodes, E. K. Wei, R. J. Salway, S. Natsui, D. Silvestri, C. K. Cassel
Journal Articles
No abstract provided.
Gut Microbiota Metabolite Fights Against Dietary Polysorbate 80-Aggravated Radiation Enteritis, Y. Li, H. Xiao, J. Dong, D. Luo, H. Wang, S. Zhang, T. Zhu, C. Zhu, M. Cui, S. Fan
Gut Microbiota Metabolite Fights Against Dietary Polysorbate 80-Aggravated Radiation Enteritis, Y. Li, H. Xiao, J. Dong, D. Luo, H. Wang, S. Zhang, T. Zhu, C. Zhu, M. Cui, S. Fan
Journal Articles
© Copyright © 2020 Li, Xiao, Dong, Luo, Wang, Zhang, Zhu, Zhu, Cui and Fan. Radiation therapy is a cornerstone of modern management methods for malignancies but is accompanied by diverse side effects. In the present study, we showed that food additives such as polysorbate 80 (P80) exacerbate irradiation-induced gastrointestinal (GI) tract toxicity. A 16S ribosomal RNA high-throughput sequencing analysis indicated that P80 consumption altered the abundance and composition of the gut microbiota, leading to severe radiation-induced GI tract injury. Mice harboring fecal microbes from P80-treated mice were highly susceptible to irradiation, and antibiotics-challenged mice also represented more sensitive to …
Time To Develop Therapeutic Antibodies Against Harmless Proteins Colluding With Sepsis Mediators?, J. Li, G. Bao, H. Wang
Time To Develop Therapeutic Antibodies Against Harmless Proteins Colluding With Sepsis Mediators?, J. Li, G. Bao, H. Wang
Journal Articles
Sepsis refers to a systemic inflammatory response syndrome resulting from microbial infections, and is partly attributable to dysregulated inflammation and associated immunosuppression. A ubiquitous nuclear protein, HMGB1, is secreted by activated leukocytes to orchestrate inflammatory responses during early stages of sepsis. When it is released by injured somatic cells at overwhelmingly higher quantities, HMGB1 may induce macrophage pyroptosis and immunosuppression, thereby impairing the host's ability to eradicate microbial infections. A number of endogenous proteins have been shown to bind HMGB1 to modulate its extracellular functions. Here, we discuss an emerging possibility to develop therapeutic antibodies against harmless proteins that collude …
Supervised Machine Learning Applied To Automate Flash And Prolonged Capillary Refill Detection By Pulse Oximetry, R. B. Hunter, S. Jiang, A. Nishisaki, A. J. Nickel, N. Napolitano, K. Shinozaki, T. Li, K. Saeki, L. B. Becker, A. J. Masino, +1 Additional Author
Supervised Machine Learning Applied To Automate Flash And Prolonged Capillary Refill Detection By Pulse Oximetry, R. B. Hunter, S. Jiang, A. Nishisaki, A. J. Nickel, N. Napolitano, K. Shinozaki, T. Li, K. Saeki, L. B. Becker, A. J. Masino, +1 Additional Author
Journal Articles
No abstract provided.
The Influence Of Migraine On Driving: Current Understanding, Future Directions, And Potential Implications Of Findings, S. J. Tepper, S. D. Silberstein, N. L. Rosen, R. B. Lipton, E. B. Dennehy, S. A. Dowsett, E. Doty
The Influence Of Migraine On Driving: Current Understanding, Future Directions, And Potential Implications Of Findings, S. J. Tepper, S. D. Silberstein, N. L. Rosen, R. B. Lipton, E. B. Dennehy, S. A. Dowsett, E. Doty
Journal Articles
© 2019 Eli Lilly and Company. Headache: The Journal of Head and Face Pain published by Wiley Periodicals, Inc. on behalf of American Headache Society Objective: To review the published findings relevant to migraine and driving performance, with an intent to encourage discussion on research which may broaden understanding in this area and help educate healthcare providers and their patients. Background: Motor vehicle crashes result in more than 35,000 deaths and more than 2 million injuries annually in the United States. Migraine is one of the most prevalent diseases in the world, and many symptoms associated with migraine attacks have …
Incorporating Remote Electrical Neuromodulation (Ren) Into Usual Care Reduces Acute Migraine Medication Use: An Open-Label Extension Study, M. J. Marmura, T. Lin, D. Harris, A. Ironi, N. L. Rosen
Incorporating Remote Electrical Neuromodulation (Ren) Into Usual Care Reduces Acute Migraine Medication Use: An Open-Label Extension Study, M. J. Marmura, T. Lin, D. Harris, A. Ironi, N. L. Rosen
Journal Articles
© Copyright © 2020 Marmura, Lin, Harris, Ironi and Rosen. Background: A recent randomized controlled study showed that 66.7% (66/99) and 37.4% (37/99) of people undergoing remote electrical neuromodulation (REN), a novel non-pharmacological migraine treatment, achieve pain relief and pain freedom, respectively, at 2 h post-treatment. The participants who completed the 6-weeks double-blind phase of this study were offered to participate in an open-label extension (OLE) with an active REN device. Objective: This study investigated the clinical use of REN, focusing on its potential in reducing the use of acute migraine medications. Methods: The parent study for this open-label extension …
Significance Of Blood And Cerebrospinal Fluid Biomarkers For Alzheimer's Disease: Sensitivity, Specificity And Potential For Clinical Use, C. D'Abramo, L. D'Adamio, L. Giliberto
Significance Of Blood And Cerebrospinal Fluid Biomarkers For Alzheimer's Disease: Sensitivity, Specificity And Potential For Clinical Use, C. D'Abramo, L. D'Adamio, L. Giliberto
Journal Articles
No abstract provided.
Mesial Temporal Resection Following Long-Term Ambulatory Intracranial Eeg Monitoring With A Direct Brain-Responsive Neurostimulation System, L. J. Hirsch, E. A. Mirro, V. Salanova, T. C. Witt, C. N. Drees, M. Brown, R. W. Lee, N. Sotudeh, R. I. Kuzniecky, M. J. Morrell, +21 Additional Authors
Mesial Temporal Resection Following Long-Term Ambulatory Intracranial Eeg Monitoring With A Direct Brain-Responsive Neurostimulation System, L. J. Hirsch, E. A. Mirro, V. Salanova, T. C. Witt, C. N. Drees, M. Brown, R. W. Lee, N. Sotudeh, R. I. Kuzniecky, M. J. Morrell, +21 Additional Authors
Journal Articles
No abstract provided.
Design And Application Of Single-Cell Rna Sequencing To Study Kidney Immune Cells In Lupus Nephritis, D. A. Rao, A. Arazi, D. Wofsy, B. Diamond
Design And Application Of Single-Cell Rna Sequencing To Study Kidney Immune Cells In Lupus Nephritis, D. A. Rao, A. Arazi, D. Wofsy, B. Diamond
Journal Articles
No abstract provided.
Unique White Matter Structural Connectivity In Early-Stage Drug-Naive Parkinson Disease, V. R. Mishra, K. R. Sreenivasan, Z. Yang, X. Zhuang, D. Cordes, Z. Mari, I. Litvan, H. H. Fernandez, D. Eidelberg, R. R. Walsh, +2 Additional Authors
Unique White Matter Structural Connectivity In Early-Stage Drug-Naive Parkinson Disease, V. R. Mishra, K. R. Sreenivasan, Z. Yang, X. Zhuang, D. Cordes, Z. Mari, I. Litvan, H. H. Fernandez, D. Eidelberg, R. R. Walsh, +2 Additional Authors
Journal Articles
© 2019 American Academy of Neurology. OBJECTIVE: To investigate the topographic arrangement and strength of whole-brain white matter (WM) structural connectivity in patients with early-stage drug-naive Parkinson disease (PD). METHODS: We employed a model-free data-driven approach for computing whole-brain WM topologic arrangement and connectivity strength between brain regions by utilizing diffusion MRI of 70 participants with early-stage drug-naive PD and 41 healthy controls. Subsequently, we generated a novel group-specific WM anatomical network by minimizing variance in anatomical connectivity of each group. Global WM connectivity strength and network measures were computed on this group-specific WM anatomical network and were compared between …