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Articles 181 - 210 of 2396

Full-Text Articles in Medicine and Health Sciences

Ultrasound On The Frontlines Of Covid-19: Report From An International Webinar, R. B. Liu, V. S. Tayal, N. L. Panebianco, Y. Tung-Chen, A. Nagdev, S. Shah, E. Pivetta, P. C. Henwood, M. J. Nelson, C. L. Moore Jan 2020

Ultrasound On The Frontlines Of Covid-19: Report From An International Webinar, R. B. Liu, V. S. Tayal, N. L. Panebianco, Y. Tung-Chen, A. Nagdev, S. Shah, E. Pivetta, P. C. Henwood, M. J. Nelson, C. L. Moore

Journal Articles

No abstract provided.


Use Of Teledermatology By Dermatology Hospitalists Is Effective In The Diagnosis And Management Of Inpatient Disease., C. K. Gabel, E. Nguyen, R. Karmouta, K. J. Liu, G. Zhou, A. Alloo, R. Arakaki, Y. Balagula, V. R. Sharon, Daniela Kroshinsky, +25 Additional Authors Jan 2020

Use Of Teledermatology By Dermatology Hospitalists Is Effective In The Diagnosis And Management Of Inpatient Disease., C. K. Gabel, E. Nguyen, R. Karmouta, K. J. Liu, G. Zhou, A. Alloo, R. Arakaki, Y. Balagula, V. R. Sharon, Daniela Kroshinsky, +25 Additional Authors

Journal Articles

BACKGROUND:Patient outcomes are improved when dermatologists provide inpatient consults. Inpatient access to dermatologists is limited, illustrating an opportunity to utilize teledermatology. Little is known about the ability of dermatologists to accurately diagnose and manage inpatients using teledermatology, particularly utilizing non-dermatologist generated clinical data. METHODS:This prospective study assessed the ability of teledermatology to diagnose and manage 41 dermatology consults from a large urban tertiary care center utilizing internal medicine referral documentation and photos. Twenty-seven dermatology hospitalists were surveyed. Interrater agreement was assessed by the kappa statistic. RESULTS:There was substantial agreement between in-person and teledermatology assessment of the diagnosis with differential diagnosis …


Targeting Inflammation Driven By Hmgb1, H. Yang, H. Wang, U. Andersson Jan 2020

Targeting Inflammation Driven By Hmgb1, H. Yang, H. Wang, U. Andersson

Journal Articles

© Copyright © 2020 Yang, Wang and Andersson. High mobility group box 1 (HMGB1) is a highly conserved, nuclear protein present in all cell types. It is a multi-facet protein exerting functions both inside and outside of cells. Extracellular HMGB1 has been extensively studied for its prototypical alarmin functions activating innate immunity, after being actively released from cells or passively released upon cell death. TLR4 and RAGE operate as the main HMGB1 receptors. Disulfide HMGB1 activates the TLR4 complex by binding to MD-2. The binding site is separate from that of LPS and it is now feasible to specifically interrupt …


The Role Of Type 1 Interferons In Coagulation Induced By Gram-Negative Bacteria, X. Yang, X. Cheng, Y. Tang, X. Qiu, Z. Wang, G. Fu, J. Wu, H. Kang, H. Wang, B. Lu, +4 Additional Authors Jan 2020

The Role Of Type 1 Interferons In Coagulation Induced By Gram-Negative Bacteria, X. Yang, X. Cheng, Y. Tang, X. Qiu, Z. Wang, G. Fu, J. Wu, H. Kang, H. Wang, B. Lu, +4 Additional Authors

Journal Articles

No abstract provided.


Public Knowledge And Attitudes Towards Bystander Cardiopulmonary Resuscitation (Cpr) In Ghana, West Africa., M. Anto-Ocrah, N. Maxwell, J. Cushman, E. Acheampong, R. Kodam, C. Homan, T. Li Jan 2020

Public Knowledge And Attitudes Towards Bystander Cardiopulmonary Resuscitation (Cpr) In Ghana, West Africa., M. Anto-Ocrah, N. Maxwell, J. Cushman, E. Acheampong, R. Kodam, C. Homan, T. Li

Journal Articles

BACKGROUND AND OBJECTIVES:Early bystander cardiopulmonary resuscitation (CPR) is one of the most important predictors of out-of-hospital cardiac arrests (OHCA) survival. There is a dearth of literature on CPR engagement in countries such as Ghana, where cardiovascular events are increasingly prevalent. In this study, we sought to evaluate Ghanaians' knowledge of and attitudes towards bystander CPR, in the context of the country's nascent emergency medicine network. METHODS:Capitalizing on the growing ubiquity and use of social media across the country, we used a novel social media sampling strategy for this study. We created, pre-tested, and distributed an online survey, using the two …


Ultrasound Identification Of Retrobulbar Hematomas By Emergency Physicians In A Cadaveric Model, E. Carlin, A. Palmieri, T. Bajaj, M. Nelson Jan 2020

Ultrasound Identification Of Retrobulbar Hematomas By Emergency Physicians In A Cadaveric Model, E. Carlin, A. Palmieri, T. Bajaj, M. Nelson

Journal Articles

Copyright: © 2020 Carlin et al. This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) License. See: http://creativecommons.org/licenses/by/4.0/ Introduction: Retrobulbar hemorrhage (RBH) is a rare complication of facial trauma that can lead to dangerous orbital compartment pressures and must be rapidly recognized to prevent permanent vision loss. Point-of-care ultrasound (POCUS) offers a rapid modality for evaluating a wide variety of ocular pathologies, and prior case reports demonstrate the ability of clinicians to recognize RBH using ultrasound. This study aimed to assess the ability of clinicians at various stages of …


A Framework For Advancing Our Understanding Of Cancer-Associated Fibroblasts, E. Sahai, I. Astsaturov, E. Cukierman, D. G. Denardo, M. Egeblad, R. M. Evans, D. Fearon, R. G. Maki, D. C. Ramirez, Z. Werb, +10 Additional Authors Jan 2020

A Framework For Advancing Our Understanding Of Cancer-Associated Fibroblasts, E. Sahai, I. Astsaturov, E. Cukierman, D. G. Denardo, M. Egeblad, R. M. Evans, D. Fearon, R. G. Maki, D. C. Ramirez, Z. Werb, +10 Additional Authors

Journal Articles

No abstract provided.


Covid-19 And Thrombotic Or Thromboembolic Disease: Implications For Prevention, Antithrombotic Therapy, And Follow-Up: Jacc State-Of-The-Art Review, B. Bikdeli, M. V. Madhavan, D. Jimenez, T. Chuich, I. Dreyfus, E. Driggin, C. D. Nigoghossian, W. Ageno, A. C. Spyropoulos, G. Y. Lip, +10 Additional Authors Jan 2020

Covid-19 And Thrombotic Or Thromboembolic Disease: Implications For Prevention, Antithrombotic Therapy, And Follow-Up: Jacc State-Of-The-Art Review, B. Bikdeli, M. V. Madhavan, D. Jimenez, T. Chuich, I. Dreyfus, E. Driggin, C. D. Nigoghossian, W. Ageno, A. C. Spyropoulos, G. Y. Lip, +10 Additional Authors

Journal Articles

© 2020 American College of Cardiology Foundation Coronavirus disease-2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), may predispose patients to thrombotic disease, both in the venous and arterial circulations, because of excessive inflammation, platelet activation, endothelial dysfunction, and stasis. In addition, many patients receiving antithrombotic therapy for thrombotic disease may develop COVID-19, which can have implications for choice, dosing, and laboratory monitoring of antithrombotic therapy. Moreover, during a time with much focus on COVID-19, it is critical to consider how to optimize the available technology to care for patients without COVID-19 who have thrombotic …


Development And Validation Of Clinical Scoring Tool To Predict Outcomes Of Treatment With Vedolizumab In Patients With Ulcerative Colitis., P. S. Dulai, S. Singh, N. V. Casteele, J. Meserve, A. Winters, S. Chablaney, S. Aniwan, P. Shashi, A. Swaminath, C. Cao, +10 Additional Authors Jan 2020

Development And Validation Of Clinical Scoring Tool To Predict Outcomes Of Treatment With Vedolizumab In Patients With Ulcerative Colitis., P. S. Dulai, S. Singh, N. V. Casteele, J. Meserve, A. Winters, S. Chablaney, S. Aniwan, P. Shashi, A. Swaminath, C. Cao, +10 Additional Authors

Journal Articles

BACKGROUND & AIMS:We created and validated a clinical decision support tool (CDST) to predict outcomes of vedolizumab therapy for ulcerative colitis (UC). METHODS:We performed logistic regression analyses of data from the GEMINI 1 trial, from 620 patients with UC who received vedolizumab induction and maintenance therapy (derivation cohort), to identify factors associated with corticosteroid-free remission (full Mayo score of 2 or less, no subscore above 1). We used these factors to develop a model to predict outcomes of treatment, which we called the vedolizumab CDST. We evaluated the correlation between exposure and efficacy. We validated the CDST in using data …


Adolescent Sjogren's Syndrome Presenting As Psychosis: A Case Series, E. K. Hammett, C. Fernandez-Carbonell, C. Crayne, A. Boneparth, R. Q. Cron, S. M. Radhakrishna Jan 2020

Adolescent Sjogren's Syndrome Presenting As Psychosis: A Case Series, E. K. Hammett, C. Fernandez-Carbonell, C. Crayne, A. Boneparth, R. Q. Cron, S. M. Radhakrishna

Journal Articles

No abstract provided.


A Quality Improvement Project To Standardize Surfactant Delivery In The Era Of Noninvasive Ventilation., J. E. Kim, M. Brewer, R. Spinazzola, E. Wallace, J. Casatelli, J. Beachy, B. Weinberger, S. Perveen Jan 2020

A Quality Improvement Project To Standardize Surfactant Delivery In The Era Of Noninvasive Ventilation., J. E. Kim, M. Brewer, R. Spinazzola, E. Wallace, J. Casatelli, J. Beachy, B. Weinberger, S. Perveen

Journal Articles

No abstract provided.


Diagnosis, Treatment, And Outcomes In Children With Congenital Nephrogenic Diabetes Insipidus: A Pediatric Nephrology Research Consortium Study, C. D'Alessandri-Silva, M. Carpenter, R. Ayoob, J. Barcia, A. Chishti, A. Constantinescu, K. M. Dell, J. Goodwin, C. Sethna, J. D. Mahan, +9 Additional Authors Jan 2020

Diagnosis, Treatment, And Outcomes In Children With Congenital Nephrogenic Diabetes Insipidus: A Pediatric Nephrology Research Consortium Study, C. D'Alessandri-Silva, M. Carpenter, R. Ayoob, J. Barcia, A. Chishti, A. Constantinescu, K. M. Dell, J. Goodwin, C. Sethna, J. D. Mahan, +9 Additional Authors

Journal Articles

© Copyright © 2020 D'Alessandri-Silva, Carpenter, Ayoob, Barcia, Chishti, Constantinescu, Dell, Goodwin, Hashmat, Iragorri, Kaspar, Mason, Misurac, Muff-Luett, Sethna, Shah, Weng, Greenbaum and Mahan. Background and Objectives: Congenital or primary nephrogenic diabetes insipidus (NDI) is a rare genetic disorder that severely impairs renal concentrating ability, resulting in massive polyuria. There is limited information about prognosis or evidence guiding the management of these patients, either in the high-risk period after diagnosis, or long-term. We describe the clinical presentation, genetic etiology, treatment and renal outcomes in a large group of children (89%) and white (67%). Median age at diagnosis was 4.2 months …


Advisory Committee On Immunization Practices Recommended Immunization Schedule For Children And Adolescents Aged 18 Years Or Younger - United States, 2020, C. L. Robinson, H. Bernstein, K. Poehling, J. R. Romero, P. Szilagyi Jan 2020

Advisory Committee On Immunization Practices Recommended Immunization Schedule For Children And Adolescents Aged 18 Years Or Younger - United States, 2020, C. L. Robinson, H. Bernstein, K. Poehling, J. R. Romero, P. Szilagyi

Journal Articles

No abstract provided.


Epidemiological And Clinical Characteristics Of International Travelers With Enteric Fever And Antibiotic Resistance Profiles Of Their Isolates: A Geosentinel Analysis, S. H. Hagmann, K. M. Angelo, R. Huits, K. Plewes, G. Eperon, M. P. Grobusch, A. Mccarthy, M. Libman, E. Caumes, D. H. Hamer, +15 Additional Authors Jan 2020

Epidemiological And Clinical Characteristics Of International Travelers With Enteric Fever And Antibiotic Resistance Profiles Of Their Isolates: A Geosentinel Analysis, S. H. Hagmann, K. M. Angelo, R. Huits, K. Plewes, G. Eperon, M. P. Grobusch, A. Mccarthy, M. Libman, E. Caumes, D. H. Hamer, +15 Additional Authors

Journal Articles

Copyright © 2020 American Society for Microbiology. All Rights Reserved. Enteric fever, caused by Salmonella enterica serovar Typhi (S. Typhi) and S. enterica serovar Paratyphi (S. Paratyphi), is a common travel-related illness. Limited data are available on the antimicrobial resistance (AMR) patterns of these serovars among travelers. Records of travelers with a culture-confirmed diagnosis seen during or after travel from January 2007 to December 2018 were obtained from GeoSentinel. Traveler demographics and antimicrobial susceptibility data were analyzed. Isolates were classified as nonsusceptible if intermediate or resistant or as susceptible in accordance with the participating site’s national guidelines. A total of …


Foreword: Evaluation And Management Of Overweight And Obesity In Children And Adolescents, M. Fisher Jan 2020

Foreword: Evaluation And Management Of Overweight And Obesity In Children And Adolescents, M. Fisher

Journal Articles

No abstract provided.


Functional Biology Of The Steel Syndrome Founder Allele And Evidence For Clan Genomics Derivation Of Col27a1 Pathogenic Alleles Worldwide, C. Gonzaga-Jauregui, G. Yesil, H. Nistala, A. Gezdirici, Y. Bayram, K. C. Nannuru, D. Pehlivan, B. Yuan, D. H. Tegay, J. R. Lupski, +27 Additional Authors Jan 2020

Functional Biology Of The Steel Syndrome Founder Allele And Evidence For Clan Genomics Derivation Of Col27a1 Pathogenic Alleles Worldwide, C. Gonzaga-Jauregui, G. Yesil, H. Nistala, A. Gezdirici, Y. Bayram, K. C. Nannuru, D. Pehlivan, B. Yuan, D. H. Tegay, J. R. Lupski, +27 Additional Authors

Journal Articles

© 2020, The Author(s). Previously we reported the identification of a homozygous COL27A1 (c.2089G>C; p.Gly697Arg) missense variant and proposed it as a founder allele in Puerto Rico segregating with Steel syndrome (STLS, MIM #615155); a rare osteochondrodysplasia characterized by short stature, congenital bilateral hip dysplasia, carpal coalitions, and scoliosis. We now report segregation of this variant in five probands from the initial clinical report defining the syndrome and an additional family of Puerto Rican descent with multiple affected adult individuals. We modeled the orthologous variant in murine Col27a1 and found it recapitulates some of the major Steel syndrome associated …


Longitudinal Changes In Health-Related Quality Of Life In Primary Glomerular Disease: Results From The Curegn Study, S. L. Murphy, J. D. Mahan, J. P. Troost, T. Srivastava, A. J. Kogon, Y. Cai, T. K. Davis, H. Fernandez, C. B. Sethna, V. Royal, +90 Additional Authors Jan 2020

Longitudinal Changes In Health-Related Quality Of Life In Primary Glomerular Disease: Results From The Curegn Study, S. L. Murphy, J. D. Mahan, J. P. Troost, T. Srivastava, A. J. Kogon, Y. Cai, T. K. Davis, H. Fernandez, C. B. Sethna, V. Royal, +90 Additional Authors

Journal Articles

© 2020 Introduction: Prior cross-sectional studies suggest that health-related quality of life (HRQOL) worsens with more severe glomerular disease. This longitudinal analysis was conducted to assess changes in HRQOL with changing disease status. Methods: Cure Glomerulonephropathy (CureGN) is a cohort of patients with minimal change disease, focal seNorthwell Healthntal glomerulosclerosis, membranous nephropathy, IgA vasculitis, or IgA nephropathy. HRQOL was assessed at enrollment and follow-up visits 1 to 3 times annually for up to 5 years with the Patient-Reported Outcomes Measurement Information System (PROMIS). Global health, anxiety, and fatigue domains were measured in all; mobility was measured in children; and sleep-related …


Long-Term Neurobehavioral And Quality Of Life Outcomes Of Critically Ill Children After Glycemic Control, K. V. Biagas, V. J. Hinton, N. R. Hasbani, P. M. Luckett, D. Wypij, V. M. Nadkarni, M. S. Agus, V. Srinivasan, J. Schneider, A. Natarajan, +35 Additional Authors Jan 2020

Long-Term Neurobehavioral And Quality Of Life Outcomes Of Critically Ill Children After Glycemic Control, K. V. Biagas, V. J. Hinton, N. R. Hasbani, P. M. Luckett, D. Wypij, V. M. Nadkarni, M. S. Agus, V. Srinivasan, J. Schneider, A. Natarajan, +35 Additional Authors

Journal Articles

© 2019 Elsevier Inc. Objectives: To investigate adaptive skills, behavior, and quality health-related quality of life in children from 32 centers enrolling in the Heart And Lung Failure-Pediatric INsulin Titration randomized controlled trial. Study design: This prospective longitudinal cohort study compared the effect of 2 tight glycemic control ranges (lower target, 80-100 mg/dL vs higher target, 150-180 mg/dL) 1-year neurobehavioral and health-related quality of life outcomes. Subjects had confirmed hyperglycemia and cardiac and/or respiratory failure. Patients aged 2-16 years old enrolled between April 2012 and September 2016 were studied at 1 year after intensive care discharge. The primary outcome, adaptive …


Meningococcal Vaccination: Recommendations Of The Advisory Committee On Immunization Practices, United States, 2020, S. A. Mbaeyi, C. H. Bozio, J. Duffy, L. G. Rubin, S. Hariri, D. S. Stephens, J. R. Macneil Jan 2020

Meningococcal Vaccination: Recommendations Of The Advisory Committee On Immunization Practices, United States, 2020, S. A. Mbaeyi, C. H. Bozio, J. Duffy, L. G. Rubin, S. Hariri, D. S. Stephens, J. R. Macneil

Journal Articles

© 2020. This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of meningococcal vaccines in the United States. As a comprehensive summary and update of previously published recommendations, it replaces all previously published reports and policy notes. This report also contains new recommendations for administration of booster doses of serogroup B meningococcal (MenB) vaccine for persons at increased risk for serogroup B meningococcal disease. These guidelines will be updated as needed on the basis of availability of new data or licensure of new meningococcal vaccines. ACIP recommends routine vaccination with a quadrivalent …


Physician Perceptions Of Adhd Stimulant Diversion And Misuse, N. M. Colaneri, S. A. Keim, A. Adesman Jan 2020

Physician Perceptions Of Adhd Stimulant Diversion And Misuse, N. M. Colaneri, S. A. Keim, A. Adesman

Journal Articles

© The Author(s) 2016. Objective: The recent rise in ADHD has prompted concerns about adolescents with ADHD diverting and/or misusing stimulants. This is the first study to assess physician perceptions of the pervasiveness of these issues. Method: Questionnaires were mailed to a national sample of pediatric subspecialists. Responses were analyzed (n = 826; 18% response rate) using descriptive statistics and regression analyses. Results: In the past year, 59% of physicians suspected ≥1 patient(s) with ADHD diverted stimulants. Seventy-four percent believed ≥1 patient(s) feigned symptoms to obtain an initial ADHD diagnosis; 66% believed ≥1 patient(s) wanted stimulants to improve academic performance. …


Pandemic-Related Submissions: The Challenge Of Discerning Signal Amidst Noise, L. J. Kaplan, T. P. Bleck, T. G. Buchman, R. P. Dellinger, C. S. Deutschman, J. C. Marshall, D. M. Maslove, H. Masur, M. M. Parker, J. J. Zimmerman, +4 Additional Authors Jan 2020

Pandemic-Related Submissions: The Challenge Of Discerning Signal Amidst Noise, L. J. Kaplan, T. P. Bleck, T. G. Buchman, R. P. Dellinger, C. S. Deutschman, J. C. Marshall, D. M. Maslove, H. Masur, M. M. Parker, J. J. Zimmerman, +4 Additional Authors

Journal Articles

No abstract provided.


Patient And Physician Discordance Of Global Disease Assessment In Juvenile Dermatomyositis: Findings From The Childhood Arthritis & Rheumatology Research Alliance Legacy Registry, H. Tory, D. Zurakowski, S. Kim, L. Abramson, E. Anderson, M. Andrew, N. Battle, M. Becker, B. Gottlieb, M. Simmons, +90 Additional Authors Jan 2020

Patient And Physician Discordance Of Global Disease Assessment In Juvenile Dermatomyositis: Findings From The Childhood Arthritis & Rheumatology Research Alliance Legacy Registry, H. Tory, D. Zurakowski, S. Kim, L. Abramson, E. Anderson, M. Andrew, N. Battle, M. Becker, B. Gottlieb, M. Simmons, +90 Additional Authors

Journal Articles

© 2020 The Author(s). Background: Global disease activity scores (gVAS) capture patient or family (PF) and physician (MD) assessments of disease. This study sought to measure discordance between PF and MD global activity scores in juvenile dermatomyositis (JDM), and determine factors associated with discordance. Methods: Patients with JDM were included from the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry (N = 563). PF and MD gVAS were assessed for discordance, defined as a ≥ 2-point difference. Factors associated with discordant gVAS were compared in univariate analysis. Multivariable regression analysis was used to identify predictors of discordance. Results: Almost …


Outcome Measurement Instruments For Peripheral Vascular Malformations And An Assessment Of The Measurement Properties: A Systematic Review, S. E. Horbach, A. P. Rongen, R. G. Elbers, C. M. Van Der Horst, C. A. Prinsen, P. I. Spuls, F. Blei, C. J. Van Der Vleuten, I. J. Frieden, L. M. Boon, +4 Additional Authors Jan 2020

Outcome Measurement Instruments For Peripheral Vascular Malformations And An Assessment Of The Measurement Properties: A Systematic Review, S. E. Horbach, A. P. Rongen, R. G. Elbers, C. M. Van Der Horst, C. A. Prinsen, P. I. Spuls, F. Blei, C. J. Van Der Vleuten, I. J. Frieden, L. M. Boon, +4 Additional Authors

Journal Articles

© 2019, The Author(s). Purpose: The Outcome measures for vascular malformation (OVAMA) group reached consensus on the core outcome domains for the core outcome set (COS) for peripheral vascular malformations (venous, lymphatic and arteriovenous malformations). However, it is unclear which instruments should be used to measure these domains. Therefore, our aims were to identify all outcome measurement instruments available for vascular malformations, and to evaluate their measurement properties. Methods: With the first literature search, we identified outcomes and instruments previously used in prospective studies on vascular malformations. A second search yielded studies on measurement properties of patient- and physician-reported instruments …


Proceedings From The 2NdNext Gen Therapies For Systemic Juvenile Idiopathic Arthritis And Macrophage Activation Syndrome Symposium Held On October 3-4, 2019, S. W. Canna, G. S. Schulert, A. De Jesus, A. Pickering, H. Brunner, M. Gadina, S. Levine, R. Goldbach-Mansky, B. Gottlieb, V. Delgaizo, +20 Additional Authors Jan 2020

Proceedings From The 2NdNext Gen Therapies For Systemic Juvenile Idiopathic Arthritis And Macrophage Activation Syndrome Symposium Held On October 3-4, 2019, S. W. Canna, G. S. Schulert, A. De Jesus, A. Pickering, H. Brunner, M. Gadina, S. Levine, R. Goldbach-Mansky, B. Gottlieb, V. Delgaizo, +20 Additional Authors

Journal Articles

© 2020 The Author(s). For reasons poorly understood, and despite the availability of biological medications blocking IL-1 and IL-6 that have markedly improved overall disease control, children with Systemic Juvenile Idiopathic Arthritis (SJIA) are now increasingly diagnosed with life-threatening chronic complications, including hepatitis and lung disease (SJIA-LD). On October 3-4, 2019, a two-day meeting, NextGen Therapies for Systemic Juvenile Idiopathic Arthritis (SJIA) & macrophage activation syndrome (MAS) organized by the Systemic JIA Foundation (www.systemicjia.org/) in Washington, DC brought together scientists, clinicians, parents and FDA representatives with the objectives (1) to integrate clinical and research findings in MAS and SJIA-LD, and …


Sleep Spindles Promote The Restructuring Of Memory Representations In Ventromedial Prefrontal Cortex Through Enhanced Hippocampal-Cortical Functional Connectivity, E. Cowan, A. Liu, S. Henin, S. Kothare, O. Devinsky, L. Davachi Jan 2020

Sleep Spindles Promote The Restructuring Of Memory Representations In Ventromedial Prefrontal Cortex Through Enhanced Hippocampal-Cortical Functional Connectivity, E. Cowan, A. Liu, S. Henin, S. Kothare, O. Devinsky, L. Davachi

Journal Articles

No abstract provided.


The Longitudinal Relationship Between Patient-Reported Outcomes And Clinical Characteristics Among Patients With Focal Senorthwell Healthntal Glomerulosclerosis In The Nephrotic Syndrome Study Network, J. P. Troost, A. Waldo, N. E. Carlozzi, S. Murphy, F. Modersitzki, H. Trachtman, P. H. Nachman, C. B. Sethna, P. Singer, D. S. Gipson, +36 Additional Authors Jan 2020

The Longitudinal Relationship Between Patient-Reported Outcomes And Clinical Characteristics Among Patients With Focal Senorthwell Healthntal Glomerulosclerosis In The Nephrotic Syndrome Study Network, J. P. Troost, A. Waldo, N. E. Carlozzi, S. Murphy, F. Modersitzki, H. Trachtman, P. H. Nachman, C. B. Sethna, P. Singer, D. S. Gipson, +36 Additional Authors

Journal Articles

No abstract provided.


Turner Syndrome With Y Chromosome: Spontaneous Thelarche, Menarche, And Risk Of Malignancy, E. Dabrowski, E. K. Johnson, V. Patel, Y. Hsu, S. Davis, A. L. Goetsch, R. Habiby, W. J. Brickman, C. Finlayson Jan 2020

Turner Syndrome With Y Chromosome: Spontaneous Thelarche, Menarche, And Risk Of Malignancy, E. Dabrowski, E. K. Johnson, V. Patel, Y. Hsu, S. Davis, A. L. Goetsch, R. Habiby, W. J. Brickman, C. Finlayson

Journal Articles

No abstract provided.


The Surviving Sepsis Campaign: Basic/Translational Science Research Priorities∗, C. S. Deutschman, J. Hellman, R. Ferrer Roca, D. De Backer, C. M. Coopersmith Jan 2020

The Surviving Sepsis Campaign: Basic/Translational Science Research Priorities∗, C. S. Deutschman, J. Hellman, R. Ferrer Roca, D. De Backer, C. M. Coopersmith

Journal Articles

© 2020 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved. Objectives: Expound upon priorities for basic/translational science identified in a recent paper by a group of experts assigned by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine. Data Sources: Original paper, search of the literature. Study Selection: By several members of the original task force with specific expertise in basic/translational science. Data Extraction: None. Data Synthesis: None. Conclusions: In the first of a series of follow-up reports to the original paper, several members of the original task …


Treatment Of Children And Adolescents Who Are Overweight Or Obese, S. Di Figlia-Peck, R. Feinstein, M. Fisher Jan 2020

Treatment Of Children And Adolescents Who Are Overweight Or Obese, S. Di Figlia-Peck, R. Feinstein, M. Fisher

Journal Articles

No abstract provided.


Urinary Epidermal Growth Factor As A Marker Of Disease Progression In Children With Nephrotic Syndrome, D. S. Gipson, H. Trachtman, A. Waldo, K. L. Gibson, S. Eddy, K. M. Dell, T. Srivastava, K. V. Lemley, C. B. Sethna, W. Ju, +18 Additional Authors Jan 2020

Urinary Epidermal Growth Factor As A Marker Of Disease Progression In Children With Nephrotic Syndrome, D. S. Gipson, H. Trachtman, A. Waldo, K. L. Gibson, S. Eddy, K. M. Dell, T. Srivastava, K. V. Lemley, C. B. Sethna, W. Ju, +18 Additional Authors

Journal Articles

© 2019 International Society of Nephrology Introduction: Childhood-onset nephrotic syndrome has a variable clinical course. Improved predictive markers of long-term outcomes in children with nephrotic syndrome are needed. This study tests the association between baseline urinary epidermal growth factor (uEGF) excretion and longitudinal kidney function in children with nephrotic syndrome. Methods: The study evaluated 191 participants younger than 18 years enrolled in the Nephrotic Syndrome Study Network, including 118 with their first clinically indicated kidney biopsy (68 minimal change disease; 50 focal seNorthwell Healthntal glomerulosclerosis) and 73 with incident nephrotic syndrome without a biopsy. uEGF was measured at baseline for …