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Full-Text Articles in Medicine and Health Sciences

Antimicrobial Effect Of High Dose Ascorbate In Mouse Model With Bacterial Infection, Chulamartd Wirapakorn Jan 2017

Antimicrobial Effect Of High Dose Ascorbate In Mouse Model With Bacterial Infection, Chulamartd Wirapakorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Ascorbate or Vitamin C is a vitamin that is important to the body. It contributes to the immunity, involves the collagen formation, acts as an antioxidant and has the ability to destroy cancer cells and bacteria. These abilities depend on the concentration of ascorbate. Bactericidal properties of ascorbate were interesting, especially in the high concentrations. Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii, and Escherichia coli are a common etiologies of nosocomial infection in Thailand and worldwide. These bacteria have developed mechanisms of antibiotics resistance and cause more violence in the disease. Hence, the time-killing assay was used to explore the bactericidal …


Immune Response In Pythiosis Patients Treated With Pythium Insidiosum Antigen (Pia), Navaporn Worasilchai Jan 2017

Immune Response In Pythiosis Patients Treated With Pythium Insidiosum Antigen (Pia), Navaporn Worasilchai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Immunotherapy using Pythium insidiosum antigen (PIA) is one of the combination treatment for P. insidiosum infected patients along with amputation and certain antifungal agents. The protocol of first prime (day0) after diagnosis and six booster doses (at 0.5, 1, 1.5, 3, 6, 12 months; mo.) along a year period were performed based on previous study. The switching of T-helper2 (Th2) to Th1 after immunotherapy along with the clinical improvement in equine and rabbit models were revealed whereas studies in human are very limited. To investigate the immune response in PIA treated pythiosis patients, cytokine profile (CMI response), P. insidiosum specific …


The Antiviral Activity Of Phenolic Lipids Group Against Dengue Virus, Parichat Kanyaboon Jan 2017

The Antiviral Activity Of Phenolic Lipids Group Against Dengue Virus, Parichat Kanyaboon

Chulalongkorn University Theses and Dissertations (Chula ETD)

Dengue virus causes a global burden that specific chemotherapy has not been established in a clinical setting. A previous report suggested that anacardic acid saturated (C15:0), a member of phenolic lipids, inhibited hepatitis C virus infection. Here, we explored structure activity relationship of phenolic lipids homologues with anti-DENV properties in the cell-based system. Our results indicated that Cardol triene (C15:3) expressed DENV1-4 inhibition, but not to Zika virus (SV0010/15) with the EC50s of 5.35 ± 1.16 µM, 7.13 ± 0.72 µM, 8.98 ± 1.77 µM, and 8.21 ± 0.34 µM, respectively. Also, the compound showed good CC50s to Vero cells …


Combination Effect Of Cepharanthine And 5-Fluorouracilon Human Colon Cancer In A Mouse Xenograft Model, Chanaporn Kongsaden Jan 2017

Combination Effect Of Cepharanthine And 5-Fluorouracilon Human Colon Cancer In A Mouse Xenograft Model, Chanaporn Kongsaden

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cepharanthine (CEP), an alkaloid isolated from the root of Stephania cepharantha Hayata, was reported to possess anticancer activity in various cancers, including colon cancer. Recently, it has been shown to enhance anti-cancer activity of 5-fluorouracil (5-FU) against human colon cancer in vitro. The present study aimed to evaluate the effect of CEP alone and CEP in combination with 5-FU in a colon cancer xenograft model. HT-29 tumors were established in the right flank of nude mice. Then, HT-29 tumor bearing mice were treated with either 5-FU or CEP alone or 5-FU combined with CEP by intraperitoneal injection every other day …


Cadaveric Evaluation Of The Location Of Arteries And Their Anastomotic Territories On The Face: The Feasibility Determination Of Risky Severe Complications Regarding To The Filler Injections Sites, Benrita Jitaree Jan 2017

Cadaveric Evaluation Of The Location Of Arteries And Their Anastomotic Territories On The Face: The Feasibility Determination Of Risky Severe Complications Regarding To The Filler Injections Sites, Benrita Jitaree

Chulalongkorn University Theses and Dissertations (Chula ETD)

The facial aging features are most concerns; therefore, the filler injection procedures are selected to provide the youthful face. However, the several complications following arterial devastating have been reported continually. Therefore, this study objectively evaluated the arterial location relative to filler injection sites. Furthermore, the arterial anastomoses and arterial supply of each injection site were also studied to verify the filler embolic pathways. This dissection was performed on 62 hemi-faces Thai embalmed cadavers to investigate nearest artery and its location of all injection sites. While, the 20 hemi-faces Thai embalmed cadavers were employed with Sihler's staining procedure to examine the …


Molecular Epidemiology And Genome Analysis Of Hepatitis E Virus In Swine And Blood Donors, Duangnapa Intharasongkroh Jan 2017

Molecular Epidemiology And Genome Analysis Of Hepatitis E Virus In Swine And Blood Donors, Duangnapa Intharasongkroh

Chulalongkorn University Theses and Dissertations (Chula ETD)

Hepatitis E virus (HEV) infection affects approximately 20 million individuals and results in more than 50,000 deaths each year. The highest prevalence is in Asia where contaminated food and water are often the sources of infection. There was the difference among the genotype of human Hepatitis E virus which genotype 1 to 4 can infect human. HEV genotypes 1 and 2 are found only in humans and are responsible for viral hepatitis outbreaks, while genotypes 3 and 4 are zoonotic. The HEV infection in Thailand caused by HEV genotype 3f and usually found among adult males. However, the route of …


Assessment Of Human Papillomavirus Detection Using Different Methods And Clinical Samples, Pornjarim Nilyanimit Jan 2017

Assessment Of Human Papillomavirus Detection Using Different Methods And Clinical Samples, Pornjarim Nilyanimit

Chulalongkorn University Theses and Dissertations (Chula ETD)

Human papillomavirus (HPV) is the etiological agent implicated cancers include those of the cervix, vulva, vagina, penis, anus, rectum and oropharynx. Currently, the Papanicolaou (Pap) smear is the recommended for cervical cancer screening but only a small percentage of women follow this screening. Overall, this thesis aimed to develop the technique and type of specimen to detect HPV DNA in Thai population and to characterize of the HPV genotypes in Thai patients with anogenital warts. Cervical swab and urine sample of 116 women and 100 men were collected before the Pap smear test. The histological examination of women can classified …


Lipoic Acid-Incorporated Calcium Carbonate Nanoparticlesfor Controlling Of Adipose Derived Stem Cells (Adscs) Differentiation And Adipocyte Function, Sarocha Cherdchom Jan 2017

Lipoic Acid-Incorporated Calcium Carbonate Nanoparticlesfor Controlling Of Adipose Derived Stem Cells (Adscs) Differentiation And Adipocyte Function, Sarocha Cherdchom

Chulalongkorn University Theses and Dissertations (Chula ETD)

CaCO3 NPs has received a growing interest due to its potential properties as a safe drug carrier. The LA-CaCO3 NPs were synthesized by a chemical precipitation method and characterized using transmission electron microscopy, thermogravimetric analysis, and zeta potential measurement. We used LA-CaCO3 NPs to evaluate their therapeutic effects in lipid accumulation, lipolysis, adipogenesis, and adipokines expression in ADSCs and differentiated adipocytes. The average particle sizes were observed to be 10-20 nanometers. Thermogravimetric analysis results confirmed the percentages of LA in CaCO3 NPs. The zeta potential showed a negative charge -30.9 mV. Our findings indicated that LA-CaCO3 NPs were apparently more …


Effects Of Curcumin On Oxidative Stress, Inflammation And Apoptosis In L-Arginine Induced Acute Pancreatitis In Mice, Thidarat Chingchit Jan 2017

Effects Of Curcumin On Oxidative Stress, Inflammation And Apoptosis In L-Arginine Induced Acute Pancreatitis In Mice, Thidarat Chingchit

Chulalongkorn University Theses and Dissertations (Chula ETD)

L-arginine (L-arg) is an amino acid that has been used to induce acute pancreatitis (AP) in mice. Curcumin is an active ingredient constituent of rhizomes of the plant Curcuma longa Linn. It has been used for the treatment of inflammatory conditions and shown to exhibit a variety of biological activities such as anti-inflammatory and anti-oxidant. The present study aims to examine the effects of curcumin on oxidative stress, inflammation and apoptosis in AP. Male ICR mice were randomly divided into 4 groups. 1) Control group, mice will be received i.p. of 1% DMSO as a vehicle. 2) AP group, mice …


Effect Of Calcium Citrate In Calcium Carbonate Nanoparticles On Hk-2 Cells In Acidic Environment, Tipagorn Udomsinsirikul Jan 2017

Effect Of Calcium Citrate In Calcium Carbonate Nanoparticles On Hk-2 Cells In Acidic Environment, Tipagorn Udomsinsirikul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Metabolic acidosis exerts several cellular and tissue dysfunctions, such as increases mineral bone and protein degradation, induces inflammation, oxidative stress and cell death. These complications lead to multiple organ failure, including chronic kidney disease. Sodium bicarbonate and Shohl's solution are commonly used to treat metabolic acidosis. However, these agents cause frequent gastrointestinal adverse effects. Hence, we invented the new calcium carbonate nanoparticles to use as a drug delivery system for carrying citrate to renal cell which we hypothesize to reduce adverse effects of metabolic acidosis. We studied the physical characteristics and pharmacological effects of calcium citrate nanoparticle (Cacit) and calcium …


Development Of Parkinson’S Glove For Detection And Suppression Of Hand Tremor At Rest Among The Tremor-Dominant Parkinson’S Disease Patients With Medically Intractable Tremor., Onanong Jitkritsadakul Jan 2017

Development Of Parkinson’S Glove For Detection And Suppression Of Hand Tremor At Rest Among The Tremor-Dominant Parkinson’S Disease Patients With Medically Intractable Tremor., Onanong Jitkritsadakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objectives of this study were to determine the efficacy of an electrical muscle stimulation (EMS) as a treatment for drug resistant tremor in PD patients by identifying of the most suitable stimulation protocols for tremor reduction and to seek out for the best location for placement of the surface electrodes (phase 1) and developing the Parkinson's glove and test for its efficacy in suppression of hand tremor at rest among the tremor-dominant Parkinson's disease patients with medically intractable tremor (phase 2). From phase 1 study, 34 PD patients with classic resting tremor was recruited. The suitable stimulation protocol and …


Factors Relating To Methamphetamine Relapse Risk Among Clients In The Substance Rehabilitation Center Of National Narcotics Boards In West Java, Indonesia, Gian Nurmaindah Hendianti Jan 2017

Factors Relating To Methamphetamine Relapse Risk Among Clients In The Substance Rehabilitation Center Of National Narcotics Boards In West Java, Indonesia, Gian Nurmaindah Hendianti

Chulalongkorn University Theses and Dissertations (Chula ETD)

The purposes of this descriptive correlational research were to describe methamphetamine relapse risk and examine the relationship between self-efficacy, outcome expectancy, motivation, coping, emotional state, craving, social support, and methamphetamine relapse risk among methamphetamine users. The purposive sample of 165 who met the inclusion criteria were recruited from clients admitted to a primary phase treatment in the Substance Rehabilitation Center of National Narcotics Board in West Java, Indonesia. The research instruments were: 1) the demographic characteristic questionnaire, 2) Drug Taking Confidence Questionnaire, 3) Stimulant Effect Expectancy Questionnaire, 4) Stage of Change Readiness and Treatment Eagerness Scale version 8.0 for Drug, …


Factors Influencing On Nursing Care Quality Perceived By Professional Nurses In Government Hospitals, Kingdom Of Cambodia, Virya Koy Jan 2017

Factors Influencing On Nursing Care Quality Perceived By Professional Nurses In Government Hospitals, Kingdom Of Cambodia, Virya Koy

Chulalongkorn University Theses and Dissertations (Chula ETD)

This descriptive cross-sectional research design for causal modeling aimed to examine factors influencing on nursing care quality in government hospitals, Cambodia. The conceptual framework were modified from the Nurse Work Environment, Nurse Staffing, and Outcome Model and empirical studies. A multi-stage sampling was used for data collection, which conducted from October 2016 to April 2017. Three hundred and seventy five RNs represented twelve tertiary general hospitals were invited for the study. All of participants completed five questionnaires, including demographic data and nurse staffing, nurse practice environment, nursing work index, Copenhagen burnout inventory, Index work satisfaction, and Cambodian nursing care quality …


Comparative Study Of In Vivo Bone Regeneration Using Chitosan/Dicarboxylic Acid Scaffold Implanted With Human Periodontal Ligament Cells, Teerawat Sukpaita Jan 2017

Comparative Study Of In Vivo Bone Regeneration Using Chitosan/Dicarboxylic Acid Scaffold Implanted With Human Periodontal Ligament Cells, Teerawat Sukpaita

Chulalongkorn University Theses and Dissertations (Chula ETD)

After tooth loss, a consequent atrophy of the alveolar process always takes place and adversely affect the reconstruction process especially by dental implant. A novel chitosan/dicarboxylic acid scaffold (CS/DA scaffold) has been developed and proven to be an excellent candidate material in bone tissue engineering. This study aimed to evaluate the effects of a CS/DA scaffold with and without seeded primary human periodontal ligament cells (hPDLCs) in mouse calvarial defect model. Eighteen mice were divided into 3 groups of 6 each. Four-millimeter calvarial defects were created on both side of parietal bone and implanted with either CS/DA scaffold or CS/DA …


Induction Of S100a7 Expression From Mechanical Stress-Induced Human Dental Pulp Cells And Its Effect On Osteoclastogenesis, Hataichanok Charoenpong Jan 2017

Induction Of S100a7 Expression From Mechanical Stress-Induced Human Dental Pulp Cells And Its Effect On Osteoclastogenesis, Hataichanok Charoenpong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Mechanical injuries of dental pulp tissues could lead to root resorption by osteoclast/odontoclast. S100A7 has been demonstrated to involve in inflammatory processes and potentially involved in bone destruction. However, the roles of S100A7 in dental pulp have not been reported. Therefore, this this study aimed to investigate the effect of mechanical stress on S100A7 expression in human dental pulp cells (hDPCs) and to investigate the effect of S100A7 protein on osteoclast differentiation. HDPCs were stimulated with in vitro compressive loading. Cell viability was determined using MTT assay. Real-time PCR (qPCR) and ELISA were utilized to determine the mRNA and protein …


The Application Of Prostacyclin In Promoting Angiogenesis Of Dental Pulp Tissue In A Three Dimensional Organ Culture System, Sonntana Seang Jan 2017

The Application Of Prostacyclin In Promoting Angiogenesis Of Dental Pulp Tissue In A Three Dimensional Organ Culture System, Sonntana Seang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Dental pulp vitality can be threatened by carious or iatrogenic exposure that can lead to pulp tissue loss. The formation of a vascular network is crucial to provide a suitable environment for tissue regeneration. Thus, promoting angiogenesis is essential for successful pulpal repair in regenerative endodontics therapy. Iloprost, a prostacyclin analog, promotes vascularization in several organs such as, heart, lung, and corneal. Previously, it has been demonstrated that, iloprost induced pulpal blood flow and enhanced dentin formation in a rat mechanical pulp exposure model. However, the angiogenic effect of iloprost on the human dental pulp vasculature remains unknown. Objective: …


Effect Of Curcumin On The Expression Of Wound Healing-Related Genes In Human Gingival Fibroblasts, Auspreeya Rujirachotiwat Jan 2017

Effect Of Curcumin On The Expression Of Wound Healing-Related Genes In Human Gingival Fibroblasts, Auspreeya Rujirachotiwat

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study investigated the effect of curcumin on the expression of wound healing-related genes including transforming growth factor beta 1 (TGF-β1), transforming growth factor beta receptor type I (TGFβR I), transforming growth factor beta receptor type II (TGFβR II) and vascular endothelial growth factor (VEGF) in human gingival fibroblasts. The cytotoxicity of curcumin was determined by MTT assay. Then, cells were treated with non-cytotoxic concentrations of curcumin for 24 hours and the level of gene expression was determined by quantitative polymerase chain reaction (qPCR). Curcumin at 0.1-20 µM caused no significant change in cell viability while higher concentrations of curcumin …


Factors Associated With Dental Caries Experience In Thai Preschool Children With Cerebral Palsy Attending Non-Governmental Rehabilitation Centers, Kullanant Pansrimangkorn Jan 2017

Factors Associated With Dental Caries Experience In Thai Preschool Children With Cerebral Palsy Attending Non-Governmental Rehabilitation Centers, Kullanant Pansrimangkorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objective: To investigate factors associated with dental caries experience in preschool children with cerebral palsy attending physical therapy programs in non-governmental rehabilitation centers in Bangkok. Materials and Methods: This research is a cross sectional study of 60 children with cerebral palsy, aged 3-6 years, mean age 5.01 ± 1.23 years old. Dental caries experience was determined by dmfs index, numbers of surfaces of dental caries, extracted tooth, and filled tooth. The other variables were collected including: dental plaque index (OHI-S), type of cerebral palsy, frequency of carbohydrate intake events, dietary consistency, assisting with toothbrushing, and frequency of toothbrushing. Multiple linear …


Clinical Efficacy Of Biocellulose Wound Dressing Containing Silk Sericin And Polyhexamethylene Biguanide For Split-Thickness Skin Graft Donor Sites, Supamas Napavichayanun Jan 2017

Clinical Efficacy Of Biocellulose Wound Dressing Containing Silk Sericin And Polyhexamethylene Biguanide For Split-Thickness Skin Graft Donor Sites, Supamas Napavichayanun

Chulalongkorn University Theses and Dissertations (Chula ETD)

A biocellulose wound dressing composed of silk sericin as an accelerative wound healing component and polyhexamethylene biguanide (PHMB) as an antimicrobial agent which showed effective and safe wound treatment. A prospective, single-blinded, randomized controlled matched-pair study was designed to evaluate the safety and the clinical efficacy of the biocellulose wound dressing containing silk sericin and PHMB compared with Bactigras® in healthy volunteers (phase I clinical study) and in split-thickness skin graft (STSG) donor site wound treatment (phase II clinical study). There were 105 healthy volunteers in phase I clinical study. The results showed that the erythema and melanin levels of …


Toxicity Of Silver, Silver-Copper And Silver-Tin Nanoparticles In Thp-1 Cell Line And Thp-1 Differentiated Macrophage Cells, Patamaporn Monprasit Jan 2017

Toxicity Of Silver, Silver-Copper And Silver-Tin Nanoparticles In Thp-1 Cell Line And Thp-1 Differentiated Macrophage Cells, Patamaporn Monprasit

Chulalongkorn University Theses and Dissertations (Chula ETD)

Silver nanoparticles (AgNPs) and nanoparticles in the form of silver-metal alloy, such as silver-copper (AgCuNPs) and silver-tin (AgSnNPs) have been applied in various industries and medical applications. To assess effects of these nanoparticles on human immune system, this study aimed to assess toxicity of AgNPs, AgCuNPs and AgSnNPs on human monocytes, THP-1 cells, and THP-1 differentiated macrophage cells. The nanoparticles were characterized and assessed for cytotoxicity and generation of intracellular ROS. Effects of the nanoparticles on the release of cytokines (TNF-α, IL-1β and IL-8) were also assessed. The results demonstrated no significant cytotoxicity of silver and silver-metal nanoparticles at the …


Anatomical And Biomechanical Factors Associated With Plantar Fasciitis In Thai Male Conscripts, Pavinee Harutaichun Jan 2017

Anatomical And Biomechanical Factors Associated With Plantar Fasciitis In Thai Male Conscripts, Pavinee Harutaichun

Chulalongkorn University Theses and Dissertations (Chula ETD)

Etiology of plantar fasciitis among novice conscripts is multifactorial. The combination of all potential factors should be included for multivariate analysis to determine the significant predictors. The present study aimed to identify the intrinsic predictors of plantar fasciitis among novice conscripts. Two hundred and seventy healthy male conscripts who were without lower back or lower extremity pain prior to the commencement of military training were participated in this study. Intrinsic predictors which included individual, anatomical, and biomechanical variables were assessed at baseline. After 10 weeks of training, 113 participants were assessed again and classified as having (n = 71) or …


Comparisons Of The Four Square Step Test And The Four Square Step Test On Foam Surface In Their Accuracy To Discriminate Between Elderly With And Without Fall History, Phakkanut Mathurapongsakul Jan 2017

Comparisons Of The Four Square Step Test And The Four Square Step Test On Foam Surface In Their Accuracy To Discriminate Between Elderly With And Without Fall History, Phakkanut Mathurapongsakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

The aims of this study were 1) to investigate the intra-rater reliability, inter-rater reliability and concurrent validity of the four square step test with foam (FSST+foam) and 2) to compare the four square step test (FSST) and the FSST+foam in their accuracy for discriminating among faller elderly, non-faller elderly, and adults. Twelve participants (4 each group) were assessed by the FSST, FSST+foam, timed up and go test (TUG) and five times sit to stand test (FTSST). The intraclass correlation coefficient and correlation coefficient were calculated to determine the reliability and validity, respectively. To investigate the accuracy for discriminating between groups, …


Subjective And Objective Outcomes On Denture Adhesive Usage Among Complete Denture Wearers, Budsara Thongyoi Jan 2017

Subjective And Objective Outcomes On Denture Adhesive Usage Among Complete Denture Wearers, Budsara Thongyoi

Chulalongkorn University Theses and Dissertations (Chula ETD)

The propose of this clinical study was to evaluate the subjective and objective assessment factors affecting decision of complete denture wearers to use or not use denture adhesive. Sixty-six fully edentulous using upper and lower conventional complete dentures (aged 53 to 83 years) were recruited in this study. (1) Condition of denture-supporting tissue (ACP classification), (2) denture quality (CU-modified kapur criteria), (3) patients' satisfaction in prostheses and (4) oral impact on daily performances (OIDP) were evaluated as baseline (T0). All participants were assigned to use denture adhesive (Polident®, Ireland) for 1 month period and made decision by themselves to continue …


Effect Of 3-Methacryloxypropyltrimethoxysilane Modified Zinc Oxide Nanoparticles Incorporated In Polymethylmethacrylate Material On Antifungal, Optical And Mechanical Properties, Krid Kamonkhantikul Jan 2017

Effect Of 3-Methacryloxypropyltrimethoxysilane Modified Zinc Oxide Nanoparticles Incorporated In Polymethylmethacrylate Material On Antifungal, Optical And Mechanical Properties, Krid Kamonkhantikul

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to evaluate 1) the characteristics of different amount of 3-methacryloxypropyltrimethoxysilane (MPS) deposited on zinc oxide nanoparticles (ZnOnps) by Fourier transform infrared spectroscopy (FTIR) and thermogravimetric analysis (TGA) before and after tetrahydrofuran washing, 2) the effect of different MPS amount deposited on ZnOnps incorporated in PMMA material on mechanical properties, and 3) the effect of different ZnOnps amounts with or without MPS incorporated in PMMA material on antifungal, optical and mechanical properties. The FTIR and TGA results showed the success of silanization. The monolayered silane molecules were parallelly oriented on the ZnOnps surface. The different MPS amounts (0-14.4 …


The Quality Of Complete Denture, Patient's Satisfaction, Oral Health-Related Quality Of Life, And Their Association, Nareudee Limpuangthip Jan 2017

The Quality Of Complete Denture, Patient's Satisfaction, Oral Health-Related Quality Of Life, And Their Association, Nareudee Limpuangthip

Chulalongkorn University Theses and Dissertations (Chula ETD)

The objective of this study was to determine the association of complete denture quality, patient's satisfaction, and Oral Health-related Quality of Life (OHRQoL). A total of 126 complete denture wearers was interviewed for the primary outcome, OHRQoL, using Oral Impacts on Daily Performances (OIDP) index. Secondary outcomes were patient's satisfaction and masticatory performance. Denture retention and stability were scored following the conventional and Chulalongkorn University (CU)-modified Kapur criteria. Esthetic-assessment criteria was evaluated from patient's photographs. It was found that limited eating/chewing was the most common problem, and an ill-fitting denture was a primary cause of any reported problems. Unacceptable denture …


The Synthesis, Modification And Application Of Silica Nanoparticles In Polymethyl Methacrylate Denture Base, Pornpot Jiangkongkho Jan 2017

The Synthesis, Modification And Application Of Silica Nanoparticles In Polymethyl Methacrylate Denture Base, Pornpot Jiangkongkho

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to investigate amount of γ-methacryloxypropyltrimethoxysilane (MPS) silanized on experimental nanosilica particles (NPs), amount of NPs and amount of MPS silanized NP on flexural strength (FS), flexural modulus (FM), and fracture toughness (FT) of NP reinforced polymethymethacrylate (PMMA). The chemisorbed amount of MPS was determined using elemental analysis. Six groups (n=8) were prepared with chemisorbed amount and mixed with PMMA-monomer to make 0.25, 0.5, 1, 5, 10 and 15% (w/w) of NP reinforced PMMA. PMMA without NP served as control. Seven groups (n=8) were prepared with 1% of NPs silanized with 0, 0.061, 0.123, 0.246, 0.493, 0.987, and …


The Inflammatory Response Of Epithelial Cell To Corrosion Products From Recast Palladium -Silver Alloy, Verapol Singkarlsiri Jan 2017

The Inflammatory Response Of Epithelial Cell To Corrosion Products From Recast Palladium -Silver Alloy, Verapol Singkarlsiri

Chulalongkorn University Theses and Dissertations (Chula ETD)

In dentistry, there is an increase in alternative metals such as palladium or silver to add into noble metal alloys in order to improve properties and reduce cost. Apart from using other metals to replace gold or platinum, reuse is another way to save the cost. There are many studies on the recast dental alloys on mechanical properties and how many percentages of new alloys needed to add in the recasting process. It has been well accepted that amount of new and used alloys would affect the mechanical and physical properties. The biocompatibility of the alloys, however, has not been …


Effectiveness Of An Educational Program To Promote The Safe Use Of Pesticide Among Vegetable Farmers In India : A Quasi Experimental Study, Ajit Pal Singh Raina Jan 2017

Effectiveness Of An Educational Program To Promote The Safe Use Of Pesticide Among Vegetable Farmers In India : A Quasi Experimental Study, Ajit Pal Singh Raina

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: 1)To provide information on baseline use and Health impacts of pesticides. 2) To provide information on knowledge, attitude, and Practice for pesticide. 3) To design a self- explanatory and affordable educational tool for vegetable farmers which can be used to train farmers on safe use of pesticides and finally 4) To assess change in KAP score and reduction in pesticide exposure symptoms to farmers and their families. Methods: After developing a simple educational tool, its effectiveness was assessed by measuring change in mean scores of knowledge, attitude, practice (KAP) and in-home pesticide safety behavior in households of farmers. Pictorial …


Associated Factors Of Hepatitis C Infection In Pregnantwomen At Outpatient Department Of Peoples Medical University And Hospital District Shaeed Benazir Abadsindh Province Pakistan, Akhlaque Hussain Jan 2017

Associated Factors Of Hepatitis C Infection In Pregnantwomen At Outpatient Department Of Peoples Medical University And Hospital District Shaeed Benazir Abadsindh Province Pakistan, Akhlaque Hussain

Chulalongkorn University Theses and Dissertations (Chula ETD)

Purpose: The prevalence of hepatitis C is 3% of the world population with more the 3 million new cases are being reported, In Pakistan, the prevalence of hepatitis C virus Infection ranges from 8%-15% in the general population. In Pakistan about 13 million people are infected. Prevalence of hepatitis C in pregnancy has been studied across Pakistan and is reported with the range of 3.27%-8.9%. Methods: A descriptive cross sectional study was conducted between may to June 2018. in people's medical university at outpatient Department of gynaecology and obstetrics in district shaheed Benazir abad Sindh Pakistan. All pregnant Patient age …


Knowledge, Attitude And Cultural Factors Towards Utilization Of Insecticide Treated Nets (Itns) Among Rakhine Ethnic Group In Ann Township, Rakhine State, Myanmar, Aung Phyo Oo Jan 2017

Knowledge, Attitude And Cultural Factors Towards Utilization Of Insecticide Treated Nets (Itns) Among Rakhine Ethnic Group In Ann Township, Rakhine State, Myanmar, Aung Phyo Oo

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study is to find associations between general characteristic, knowledge, attitudes and cultural factors on malaria prevention toward utilization of insecticidal nets (ITNs) among Rakhine ethnic groups, in Ann Township, Rakhine State, Myanmar. An analytic cross sectional study was conducted among 420 Rakhine ethnic groups aged more than 18 years old from 10 villages in Ann Township. Data were collected by using face-to-face interview. The study found only 3.6% of respondents had good knowledge level, 19.0% good attitude level and 38.8% good practice level towards utilization of ITNs. Female participants were 8.015 times had good practice level than male (p-value <0.001, AOR 8.015, 95% CI = 3.395-18.923). High school level participants likely to use ITNs for 14.518 times than lower education level (p-vale <0.001, AOR 14.518, 95% CI = 4.642-45.408). Married participants were 13.753 times done good practice (p-vale <0.001, AOR 13.753, 95% CI = 4.371-43.267) and widowed participants were 5.403 times done good practice than singles (p-vale 0.039, AOR 5.403, 95% CI = 1.085-26.909). Regarding the cultural factors, participants who always worked from dawn to night time were 2.203 times had good practice level than who never work at that time (p-vale 0.032, AOR 2.203, 95% CI = 1.070-4.536). Regarding knowledge level of the participants, moderate and good knowledge level were 5.125 times had good practice level than lower knowledge level participants (p-vale <0.001, AOR 5.125, 95% CI = 1.062-6.429). Health education and encouragement of people should be done to improve knowledge and utilization to use insecticide treated nets.