Medicine and Health Sciences Commons^™

Medicine And The Holocaust: My Personal Reflections, Catherine Phamduy

Physicians and the Holocaust Student Books

What you are about to read is an accumulation of my reflections based on thought-provoking questions asked in my class “Medicine and the Holocaust”. You might know a lot about the Holocaust, yet here are just a few bits on my opinion from the standpoint of a medical student.

Medicine And The Holocaust 2020-2021: A Book Of Prayer And Reflections, Hannah L. Carson

Physicians and the Holocaust Student Books

A book of prayer and reflections written for Medicine and the Holocaust course.

Clinical And Diagnostic Imaging Manifestations Of Erdheim-Chester Disease, Avrey Thau, Roland Gazaille, Alejandro Calvo, Christina E. Borchers, Ronald E. Warwar, William Boyce, Joseph Blake

Dermatology Faculty Publications

Introduction: Erdheim-Chester disease (ECD) is a rare form of non-Langerhans-cell histiocytosis which typically presents with bilateral masses due to retro-orbital deposition, xanthelasma of the eyelids, cardiopulmonary manifestations, along with sclerosis and cortical thickening of the long bones, particularly in the lower extremities.

Case Report: We present the case of a 58-year-old male who presented to a local emergency department with a one day history of severe dizziness, diaphoresis, dyspnea, and intermittent diplopia. Imaging demonstrated bilateral symmetric retrobulbar masses. Subsequent imaging as well as orbital and bone marrow biopsies lead to the diagnosis of ECD.

Conclusion: Erdheim-Chester disease is a rare …

Fear Of Covid-19 And Depression: Mediating Role Of Anxiety And Stress Among University Students, Noreena Kausar, Amna Ishaq, Hafsa Qurban, Hafiz Abdur Rashid

Journal of Bioresource Management

Fear of CIVID-19 and psychological health issues are most common in general population, health professionals and students after emerging the COVID-19 infection. The literature review elaborated the correlation among fear of COVID-19, stress, depression and anxiety among students at different levels.The current study was conducted with two objectives. First aim was to assess the relationships among fear of COVID-19, stress, anxiety and depression among university students. The second objective was to measure the mediating role of anxiety and stress between the relationship of fear of COVID-19 and depression.Total 500 Government and private university students were selected through convenient sampling technique …

Outcome After Surgical Stabilization Of Rib Fractures Versus Nonoperative Treatment In Patients With Multiple Rib Fractures And Moderate To Severe Traumatic Brain Injury (Cwis-Tbi), Jonne T.H. Prins, Esther M. M. Van Lieshout, Francis Ali-Osman, Zachary M. Bauman, Eva-Corina Caragounis, Jeff Choi, D. Benjamin Christie Iii, Peter A. Cole, William B. Devoe, Andrew R. Doben, Evert A. Eriksson, Joseph D. Forrester, Douglas R. Fraser, Brendan Gontarz, Claire Hardman, Daniel G. Hyatt, Adam J. Kaye, Huan-Jang Ko, Kiara N. Leasia, Stuart Leon, Silvana F. Marasco, Allison G. Mcnickle, Timothy Nowack, Terri D. Ogunleye, Prakash Priya, Aaron P. Richman, Victoria Sschlanser, Gregory Semon, Ying-Hao Su, Michael H. J. Verhofstad, Julie Whitis, Fredric M. Pieracci, Mathieu M. E. Wijffels

Department of Surgery Faculty Publications

BACKGROUND

Outcomes after surgical stabilization of rib fractures (SSRF) have not been studied in patients with multiple rib fractures and traumatic brain injury (TBI). We hypothesized that SSRF, as compared with nonoperative management, is associated with favorable outcomes in patients with TBI.

METHODS

A multicenter, retrospective cohort study was performed in patients with rib fractures and TBI between January 2012 and July 2019. Patients who underwent SSRF were compared to those managed nonoperatively. The primary outcome was mechanical ventilation-free days. Secondary outcomes were intensive care unit length of stay and hospital length of stay, tracheostomy, occurrence of complications, neurologic outcome, …

Managing Work Flow In High Enrolling Trials: The Development And Implementation Of A Sampling Strategy In The Prepare Trial, David Pogorzelski, Uyen Nguyen, Paula Mckay, Lehana Thabane, Megan Camara, Lolita Ramsey, Rachel Seymour, J. Brett Goodman, Sheketha Mcgee, Joanne Fraifogl, Andrea Hudgins, Stephanie L. Tanner, Mohit Bhandari, Gerard P. Slobogean, Sheila Sprague, Jeffrey Wells, Prep-It Investigators Executive Committee

Orthopaedic Surgery Faculty Publications

Pragmatic trials in comparative effectiveness research assess the effects of different treatment, therapeutic, or healthcare options in clinical practice. They are characterized by broad eligibility criteria and large sample sizes, which can lead to an unmanageable number of participants, increasing the risk of bias and affecting the integrity of the trial. We describe the development of a sampling strategy tool and its use in the PREPARE trial to circumvent the challenge of unmanageable work flow. Given the broad eligibility criteria and high fracture volume at participating clinical sites in the PREPARE trial, a pragmatic sampling strategy was needed. Using data …

Population Pharmacokinetics Of Olanzapine In Children, Anil R. Maharaj, Huali Wu, Kanecia O. Zimmerman, Julie Autmizguine, Rohit Kalra, Amira Al‐Uzri, Catherine M.T. Sherwin, Stuart L. Goldstein, Kevin Watt, Jinson Erinjeri, Elizabeth H. Payne, Michael Cohen‐Wolkowiez, Christoph P. Hornik

Pediatrics Faculty Publications

Aims The aim of this study was to evaluate the population pharmacokinetics (PopPK) of olanzapine in children and devise a model-informed paediatric dosing scheme. Methods The PopPK of olanzapine was characterized using opportunistically collected plasma samples from children receiving olanzapine per standard of care for any indication. A nonlinear mixed effect modelling approach was employed for model development using the software NONMEM (v7.4). Simulations from the developed PopPK model were used to devise a paediatric dosing scheme that targeted comparable plasma exposures to adolescents and adults. Results Forty-five participants contributed 83 plasma samples towards the analysis. The median (range) postnatal …

Improved De Novo Alignment Of A Girardia Dorotocephala Ma-C2 (2n = 24) Transcriptome, Labib Rouhana, J F. Ryan, Eugene M. P. Almazan

Biological Sciences Faculty Publications

Improved De novo alignment of a Girardia dorotocephala MA-C2 (2n = 24) transcriptome.

Uvb-Induced Microvesicle Particle Release In Human Skin In Vivo Is Diminished Following Oral Vitamin C And E Antioxidant Administration, Cameron Mcglone

Scholarship in Medicine - All Papers

An important question in photobiology asks how Ultraviolet B (UVB, 290 – 320 nm) radiation, which mostly absorbs in the outer epidermis of skin, can generate a systemic response such as immunosuppression. Previous in vitro and ex vivo studies demonstrate UVB-dependent release of bioactive molecule-containing microvesicle particles (MVPs) from keratinocytes. Furthermore, MVP release is diminished upon antioxidant administration. The purpose of this study is to examine UVB-induced MVP release and antioxidant response in vivo. In this IRB-approved study, 8 male participants with Fitzpatrick type I or II skin were treated with 1000 J/m2 UVB irradiation to a 5 by 5 …

Risk Factors For Sudden Infant Death Syndrome: A Cdc Wonder Analysis, Elise Hoy

Scholarship in Medicine - All Papers

Objective. By definition, there is no known cause of Sudden Infant Death Syndrome (SIDS).1 The best information currently available comes from studies investigating infant sleep habits. Thus far, researchers agree that in regards to sleep, infants are safest, and at lowest risk for SIDS, when sleeping in a supine rather than prone or lateral position, when sleeping on hard, rather than soft, bedding with no pillows or blankets, and when sleeping in a crib rather than sharing a bed with a parent.1–4 In an effort to better understand what additional factors might predispose an infant to dying of SIDS, this …

Publication Status Of Unpublished Research Manuscripts On Orthopaedic Surgery Residency Applications After 30 Months, J. T. Barnes

Scholarship in Medicine - All Papers

Objectives: The orthopaedic surgery residency applicant class of 2016 had a nationwide match rate of 67.8%. This institution received 573 applications for four residency spots. As orthopaedic surgery residency becomes more competitive, so does the drive among applicants to improve their residency applications. Research experience, in particular, is becoming an increasingly common component of applications. Previous research has demonstrated that the requirement for a PubMed Identification number on all published citations on residency applications since 2014 has led to a drastic decrease in misrepresentation of published research. While publication is the ultimate goal of most research projects, not all manuscripts …

Characterization Of Inhbb, Heatr5a, & Cyp2s1 Expression In Dorsal Root Ganglia By In-Situ Hybridization, Joshua D. Krech

Browse all Theses and Dissertations

Multiple studies have shown that gene expression changes occur in sensory neurons after peripheral nerve injury (PNI). These expression changes include many genes that are turned on specifically in response to injury, but much less is know about expression changes in stable genetic markers of particular sensory neuron populations. This study characterized the expression of three markers of proprioceptive neurons Inhbb, Heatr5a, Cyp2s1 in lumbar dorsal root ganglion (DRG) neurons in intact animals and after PNI. To perform these experiments, we subcloned segments of the coding sequences of these genes and generated DIG-labeled riboprobes. Control experiments demonstrated the validity of …

Association Between Serum Vitamin D And Bone Mineral Density In Us Population, Hamza M. Sultan

Master of Public Health Program Student Publications

Osteoporosis is a condition where the bones become weak that affects 12.6% of the United States (US) population over 50 years of age. Vitamin D helps to improve bone health as it functions in helping reabsorb calcium from the intestines. Several studies have been conducted on the effects of vitamin D on Bone Mineral Density (BMD), where it has shown that insufficient vitamin D is associated with a reduction in BMD. The purpose is to determine the relationship between serum vitamin D and BMD of the femoral neck in the US population in National Health and Nutrition Examination Survey (NHANES) …

How Medical Student Adherence To Assigned Readings In A Flipped Classroom Curriculum Affects Their Outcomes, Meghan Blank

Scholarship in Medicine - All Papers

Objective: This study is aimed at finding out which level and type of preparation is most effective in helping students to achieve success in a flipped classroom curriculum.

Methods: Surveys were conducted regarding the percentage of required preparation students completed for each type of learning session (peer instruction, team-based learning), whether or not they used supplemental resources, and whether or not they completed >50% or < 50% of the required preparation. These were then compared to student scores on the type of learning activity through Spearman correlations and unpaired t-tests.

Results: The greater the percentage of required preparation completed typically resulted in higher test scores. Supplemental preparation did not directly correlate with higher test scores, with some cases showing a decrease in score with the …

Multiplex Social Factors Affecting Hiv Prevalence In Colorado, Jesse Cannella

Scholarship in Medicine - All Papers

Objective: The objective of this paper was to investigate and analyze the relationships between the prevalence of HIV and geographic location, high-risk behaviors, and education status in Colorado in 2020. Methods: The author of this paper conducted Spearmen correlations on HIV prevalence with rural status, rates of flu vaccinations, and drug overdose deaths, as well as performed stepwise linear regressions on the variance of HIV prevalence accounted for by rates of teen births, sexually transmitted infections, high school graduation, and college education status. Results: Incidence of other STIS and teen births (F2,42 = 7.69, p = .001), as well as …

Evaluating Academic Performance In Students Who Are Underrepresented In Medicine, Alexis Marrin

Scholarship in Medicine - All Papers

Objective: The purpose of this study was to investigate academic performance throughout the first two years of medical education of students who classify themselves as underrepresented in medicine (URM) as compared to non-URM students. Methods: Final exam scores from each course throughout the Foundation phase, Clinical Medicine evaluation scores, CBSE scores, and Step 1 scores from three classes of medical students at Wright State University Boonshoft School of Medicine were analyzed using multiple linear regression models, while controlling for MCAT percentile, undergraduate science GPA, and gender. Results: URM students enter medical school with lower entrance data than non-URM students, and …

Signing Your Life Away? Emergency Department Patient Recall And Understanding Of Ed Consent For Treatment Based On Triage Level, Daniel Ross

Scholarship in Medicine - All Papers

Objective: The determine the correlation between patient recall and understanding of Emergency Department (ED) consent for treatment and patient triage level. Methods: This was a prospective study based on demographical and triage data collected from patient charts, in combination with patient responses to the consent for treatment survey. Results: Of the 293 that participated in the study, the mean age was 52, with 122 (41.6%) males and 171 (58.4%) females. 179 (61.5%) identified as white/Caucasian and 100 (34.4%) identified as African-American. Most patients, 210 (72.4%), arrived by walk-in and the rest, 80 (27.6%), were by ambulance. Participants with lower triage …

Antimicrobial Use In Positive Respiratory Viral Panel: Impact Of Procalcitonin Use And Antimicrobial Stewardship, David Beleny

Scholarship in Medicine - All Papers

increasing antibiotic resistant microbes.¹ Blood and sputum cultures are the gold standard for bacterial identification, but they are difficult to obtain and take days to receive back from the lab. Physicians commonly treat patients empirically with antibiotics because there is an increased risk of 30-day mortality in patients with bacterial community-acquired pneumonia (CAP).² Overuse of antibiotics is commonplace in hospitalized patients which is detrimental as it contributes to antibiotic resistance, costs money, wastes resources, and puts patients at risk for unnecessary adverse effects of the medications.³ It was found that 75% of patients presenting with a respiratory …

Human Immunodeficiency Virus (Hiv) – An Analysis Of Trends In Hiv Diagnoses From 2008 – 2018, Ulysses G. Gardner

Scholarship in Medicine - All Papers

Objective: An estimated 1.1 million people are living with the human immunodeficiency virus (HIV) in the United States. Despite over two decades of research, a cure for HIV has not been approved and it remains a pandemic. This research study was conducted to determine the statistical significance in HIV incidence based on diagnoses in 2008 versus 2018; age groups 25-34 years old versus 55+ years old; Black versus Hispanic versus White; male versus female; and geographical location. Methods: This retrospective study was conducted using data from the Center for Disease Control and Prevention (CDC) Atlas Plus data sets, a collection …

Chlamydia In Ohio 2019, Jennifer Schmitz

Scholarship in Medicine - All Papers

Objective: Chlamydia Trachomatis is becoming an increasingly large national problem with severe consequences on the medical health care system. Methods: With data collected from County Health Ranking, with research that has been conducted at governmental and nongovernmental levels throughout the community, state and national level. Increases in rates of chlamydia can be linked to an increased number of testing or increased accuracy of testing while decreased numbers of incidence can be due to low reporting from that county. Conducting correlation and comparison may reveal additional links to the rising rates of Chlamydia. Results: We found a positive correlation between rate …

Family Structure And Pediatric Outcomes In Ohio, Andrew J. Berman

Scholarship in Medicine - All Papers

Objective: The number of single-parent households has been trending upwards since the early 1900s. Studies in the past have evaluated the effects single-parent households have on pediatric outcomes nationwide. This study attempts to build upon these past studies by analyzing whether these findings remain when looked at the State level, for Ohio 2020, as well as see if the percent of children in single-parent households can predict child mortality.

Methods: Data was collected from publicly available data sets through County Health Rankings. This study utilizes SPSS for data analysis. ANOVA with post-hoc was performed to compare children in single-parent household …

Consent For Emergency Treatment: Demographic Variables And Relationship To Patient Comprehension, Ashwatha Thenappan

Scholarship in Medicine - All Papers

Objective: One of the most important pillars of patient autonomy is informed consent for medical treatment. This study was undertaken to measure patient recall and understanding of consent for treatment among ED patients. Methods: This prospective survey study was conducted at Miami Valley Hospital, an Urban Level 1 Trauma Center. Trained research assistants obtained verbal consent in private patient treatment rooms. Data were collected from the electronic medical record and from a survey questionnaire. Results: A total of 293 patients consented to participate (95% participation rate). The majority of participants stated that they had signed a consent document (N …

Outcomes In Children And Adolescents Undergoing Cholecystectomies With A High Ejection Fraction, Salony Dighamber, Karen Herzing, Arturo Aranda, Jeffrey C. Pence, Sean Barnett

Scholarship in Medicine - All Papers

Background

Cholecystectomy is commonly performed electively for symptomatic cholelithiasis and biliary hypokinesia with an ejection fraction (EF) less than 35%. Recent literature has shown that cholecystectomy in adults for biliary hyperkinesia (EF>65%) can provide resolution of symptoms (primarily pain) for the majority of patients. We seek to determine whether cholecystectomy is efficacious in the treatment of symptomatic biliary hyperkinesia in the pediatric population.

Method

The charts of over 100 patients aged 7 to 21 in the last 10 years (2008 to 2018) who had cholecystectomies were reviewed to determine ejection fraction, BMI, race, pain with CCK-HIDA, complications, and resolution …

Pneumomediastinum Following Endotracheal Intubation, Aroh Ribadiya

Scholarship in Medicine - All Papers

EP, an 81-year-old female with a history of multiple metastases presented to the Emergency Department (ED) for shortness of breath. She developed respiratory failure requiring endotracheal intubation. She was successfully intubated, treated with etomidate, succinylcholine, propofol, fentanyl, and admitted to the Intensive Care Unit (ICU). A follow up chest CT at 2 hours demonstrated an incidental finding of pneumomediastinum.

If Gharib Hall Could Talk, Maryam Alizadeh, Dean Parmelee, Saeedreza Mehrpour

Medical Education Faculty Publications

Not only did we have to convince faculty and students that "active and engaged" learning would make for better education-a major "culture" transition-we had to create the learning spaces that would support these changes. Hafferty, in confronting hidden curriculum, has suggested that medical school is a "learning space", which sends messages to students and teachers (1). In sum, we defined the "problem" as an "opportunity" to engage students, faculty, and leadership in a process to transform the learning culture to learner-centered and this included creating a teaching-learning space to fit.

Vital Signs, Winter 2021, Boonshoft School Of Medicine

Vital Signs

A newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Advancing Motivational Interviewing Training With Artificial Intelligence: Readmi, Paul J. Hershberger, Yong Pei, Dean A. Bricker, Timothy Crawford, Ashutosh Shivakumar, Miteshkumar Vasoya, Raveendra Medaramitta, Maria Rechtin, Aishwarya Bositty, Josephine F. Wilson

Family Medicine Faculty Publications

Background: Motivational interviewing (MI) is an evidence-based, brief interventional approach that has been demonstrated to be highly effective in triggering change in high-risk lifestyle behaviors. MI tends to be underutilized in clinical settings, in part because of limited and ineffective training. To implement MI more widely, there is a critical need to improve the MI training process in a manner that can provide prompt and efficient feedback. Our team has developed and tested a training tool, Real-time Assessment of Dialogue in Motivational Interviewing (ReadMI), that uses natural language processing (NLP) to provide immediate MI metrics and thereby address the need …

Incorporation Of Feeding Functional Group Information Informs Explanatory Patterns Of Long-Term Population Changes In Fish Assemblages, Jason C. Doll, Stephen J. Jacquemin

Biological Sciences Faculty Publications

The objective of this study was to evaluate long term trends of fish taxa in southern Lake Michigan while incorporating their functional roles to improve our understanding of ecosystem level changes that have occurred in the system over time. The approach used here highlighted the ease of incorporating ecological mechanisms into population models so researchers can take full advantage of available long-term ecosystem information. Long term studies of fish assemblages can be used to inform changes in community structure resulting from perturbations to aquatic systems and understanding these changes in fish assemblages can be better contextualized by grouping species according …

Vertebrate Subfossil Localities In Taylorsville Metropark, Montgomery County, Ohio, Usa, Ryan Shell, Kristin Zimmerman, David Peterman, Charles Ciampaglio, Lauren Fuelling, Stephen J. Jacquemin

Biological Sciences Faculty Publications

Karst features in the Silurian dolomites of Taylorsville MetroPark (Dayton Metropolitan Area, Ohio, United States) were explored from 2017 to 2018 to identify sites of paleontological interest. Initial landscape surveys recovered 124 skeletal elements (from 12 sites) that were attributed to 17 vertebrate species--including evidence of such extirpated animals as bobcats (Lynx rufus) and rattlesnakes (Crotalus sp.). Of the 12 sites, 9 sites contained remains from the historical era and 3 sites contained much older remains (n = 17) that were radiocarbon dated to approximately 1,400 years before present (YBP). Human remains at one site, butchered bones at another, and …

Evaluating Winter Malting Barley Grain Yield With Fractional Green Canopy Cover, Gregory J. Mcglinch, Stephen J. Jacquemin, Laura E. Lindsey

Biological Sciences Faculty Publications

Because of growth in the craft brewing industry, farmers in the eastern United States are planting winter malting barley (Hordeum vulgare L.) to meet demands for locally sourced grain. However, given that barley is a relatively new crop in this region, basic agronomic information relating to stand assessment is needed. This is particularly relevant in this region, as climatic variability from extreme temperature fluctuations during the winter and spring can reduce a barley stand, creating the need for farmers to estimate grain yield potential. The objective of the research was to evaluate the relationship between spring stem counts, fractional …