Medicine and Health Sciences Commons^™

Adventuring Into A University Common Read Program, Emily Hurst

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Background

Each year a selection committee at a large urban university selects a book for all first year students. Books are sent out to students and then the title is used throughout many freshman level classes. Librarians are involved in the selection of the book, the creation of a resource guide with related information, and the creation of potential programs to support the themes and topics addressed in the book. The largest event is organized through the common read program and involves a lecture to the university community from the book author. For many years the book and common read …

The Self-Taught Marketers Guide To Creating An Annual Report, Everly D. Brown, Patrick T. Waugh, Tara R. Wink

Mid-Atlantic Chapter of the Medical Library Association (MAC- MLA) Annual Meeting Posters/Presentations

Objective

To produce an easy-to-read, visually appealing, 1-4 page annual report for the University of Maryland, Baltimore’s Health Sciences and Human Services Library (HSHSL). The report should be a mix of interesting statistics, highlights, stories, quotes, and photographs to promote the HSHSL’s annual accomplishments to the campus.

Methods

We gather all of the stories and statistics we think will be eligible material for the annual report, pulling content and ideas from: newsletters, workshops, blog posts, events, exhibits, and meetings with division and department heads. An annual report committee and visual designer decide upon the top stories and statistics, focusing upon …

Foxos Modulate Proteasome Activity In Human-Induced Pluripotent Stem Cells Of Huntington’S Disease And Their Derived Neural Cells, Jefin Jose

VCU's Medical Journal Club: The Work of Future Health Professionals

FOXO transcription factors have been implicated in modulating proteasome activity. Liu et al. found that Huntington's disease-induced pluripotent stem cells (HD iPSCs) exhibited greater proteasome activity as well as greater FOXO1 and FOXO4 expression. To determine a possible causal relationship, Liu et al. performed shRNA knockout of these two transcription factors and found that only FOXO4 mediated proteasome activity in pluripotent stem cells. Overexpression of FOXO4 rescued proteasomal defect in HD iPSCs-derived neural progenitor cells (NPCs). Overall, Liu et al. found that FOXO4 specifically modulated proteasome activity in HD iPSCs and their derived NPCs.

Slow-Stroke Back Massage Compared With Music Therapy For Leukemia-Related Pain And Fatigue: A Randomized Controlled Trial, Rhea Tammireddi

VCU's Medical Journal Club: The Work of Future Health Professionals

This presentation focused on the effects of nonpharmacological treatments for leukemia-related pain and fatigue. These types of treatments are becoming more prevalent in today's times due to the risk of opioid addictions with increased pain medications. The study looked at two treatments: slow-back massage therapy and music therapy. Both treatments offer various advantages physically and emotionally. The study separated 114 adults with acute myeloid leukemia into the two treatments group and a control group of standard treatment. The results showed back massage therapy had a stronger and longer effect on the reduction of pain and fatigue.

Anti-Gd2 Antibody Dinutuximab Inhibits Triple-Negative Breast Tumor Growth By Targeting Gd2+ Breast Cancer Stem-Like Cells, Nasser Al-Abdulaly

VCU's Medical Journal Club: The Work of Future Health Professionals

Triple negative breast cancer is an aggressive subtype of breast cancer characterized by its lack of estrogen and progesterone receptors, as well as no or low levels of human epidermal growth factor 2. Ly et al. found that the ganglioside GD2 is highly expressed in a stem cell-like population of triple negative breast cancer tumor and helps with cell adhesion and migration. Using a xenograft model, the researchers determined that targeting this cell population with dinutuximab (anti-GD2 antibody) could prevent tumor growth and metastasis.

Association Of Cag Repeats With Long-Term Progression In Huntington Disease, Jefin Jose

VCU's Medical Journal Club: The Work of Future Health Professionals

The relationship between CAG repeat length and clinical/morphometric decline in Huntington's disease patients beyond the age of onset has not been well characterized. Some studies argue that CAG repeat length does influence clinical decline after the age of onset, while others do not. Langbehn et al. found that clinical condition correlated quadratically with age for every subject with a pathogenic number of CAG repeats in the TRACK-HD and TRACK-ON datasets. Interestingly, those with a higher CAG repeat length experienced a greater rate of clinical decline at each timepoint. Performing a similar analysis using morphometric data, Langbehn et al. found a …

Nonpharmacological Practices For Reducing Agitation In Persons With Dementia, Meghan L. Farkas

Commonwealth Scholars Program

1 in 11 people aged 45 years and older experience subjective cognitive decline, with nearly a third identifying a decline in the ability to participate in social activities, work, or volunteering. There are twelve modifiable risk factors that can either increase or decrease an individual's possibility of developing Dementia. This can include excessive alcohol consumption, head injury, air pollution, lower education level, hypertension, hearing impairment, smoking, obesity, depression, physical inactivity, diabetes, and infrequent social contact. These modifiable risk factors may prevent or delay up to 40% of dementias. Furthermore, many risk factors cluster around inequalities, which occur particularly in Black, …

Climate Change And Mental Health: What Can We Do?, Ann N. Welch

VCU Health Nursing

Climate change has been described as the defining health issue of this century. Many aspects of mental health are affected by the events related to the earth's warming climate. This poster presentation will identify ways in which climate change affects mental health and suggest concrete actions that can be taken to help to mitigate these effects.

Using Silicone Mesh To Mitigate Risk Of Forehead Pulse Ox Pressure Injuries, Patrick Alridge

VCU Health Nursing

Introduction

In the intensive care unit (ICU) setting, patients may require the use of a pulse ox probe on the forehead to obtain an appropriate oxygenation saturation reading. The pulse ox probe has two clear plastic sensors, through which the infrared light travels to measure oxygenation. Despite applying the sensor per manufacturer’s instructions and rotating the device location on the forehead more frequently than manufacturer recommendations, the sensor can still cause a medical device-related pressure injury.

Methods

Silicone mesh dressing is commonly used under wet to dry dressings or under negative pressure wound therapy dressings to prevent adherence of the …

What Matters Most: Cna Perspectives On Workforce Education, Professional Identity And Age-Friendly Care, Shannon Arnette, Annie Rhodes, Kimberly Ivey, Christian Bergman, Leland "Bert" Waters

Case Studies from Age in Action

Learning Objectives

1. Identify the gaps in current Certified Nursing Assistant (CNA) training in relation to Delirium, Dementia(s), and Depression (3D’s).

2. Identify CNA learning preferences.

3. Review the constructed tele-education training sessions that incorporate age-friendly care and What Matters Most (WMM) to participants in regards to the 3D’s.

4. Increase the CNAs’ competency and level of comfort working with individuals living with the 3D’s.

Recognizing And Responding To Abuse In Later Life: Feedback From Virginia’S Frontline, Sarah A. Marrs, Courtney O'Hara

Case Studies from Age in Action

Learning Objectives

1. To describe a research project aimed at understanding the recognition of and response to abuse in later life in the greater Richmond area

2. To discuss the structural factors that contribute to underidentification and under-resourcing of services that address abuse in later life

3. To discuss the relationship between ageism and abuse in later life

Coping With Macular Degeneration: Three Case Studies, Ajit D. Tiwari

Case Studies from Age in Action

Educational Objectives

1. Learn about the diagnosis and available treatments for Age Related Macular Degeneration (AMD).

2. Explain the differences between Dry and Wet AMD.

3. Understand the impact of vision loss on the lives of older adults.

The Effects Of Clinical Depression On The Oral Health Of College Students, Delorias Perkins, Sarah Peng

Dental Hygiene Student Scholarship

Objectives: Mental health among college students has become a recent concern due to the rising cases of depression. In addition to the stress factors a typical college student often faces, we now have the COVID-19 pandemic that further exacerbates this issue. One’s state of mind has a significant impact on not only their mindset but their body overall. If the body’s health is impacted by depression, then it will influence the immune system and bodily function, ultimately affecting the oral cavity as well. The purpose of this review of literature is to identify the relationship between clinically diagnosed depression and …

Adult-Onset Alexander Disease Uncovered In A Previously Healthy Patient Presenting With Acute Stroke-Like Symptoms, Usaamah M. Khan, Matthew Barrett, Alex Dworetz Do

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Alexander Disease is a rare, often fatal, leukoencephalopathy of early childhood associated with a heterozygous mutation of the glial fibrillary acid protein (GFAP) gene. Adult-Onset Alexander Disease (AOAD) is an exceptionally rare leukoencephalopathy that often presents with slowly progressive brainstem and cervical cord dysfunction features. Acute onset of AOAD has only ever been reported three times in the literature. We report a case of acute onset AOAD in a patient that presented with bulbar symptoms and left hemiplegia initially concerning for acute stroke.

Patient And Provider-Level Factors That Underlie Alcohol Use Disorder Treatment Offer And Acceptance In Veterans With Cirrhosis, Nikki Duong

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Background: Untreated alcohol use disorder (AUD) is associated with poor cirrhosis outcomes. We evaluated factors associated with AUD treatment discussions and initiation in the Veterans Health Administration.

Methods: Chart reviews were conducted for veterans with International Classification of Diseases codes for both cirrhosis and AUD who were receiving care at one of three large medical centers in 2020. Factors associated with a 1-year offer of AUD treatment and its acceptance were assessed using regression models, which included as covariates demographic characteristics, comorbidities, and depression, as measured by the patient health questionnaire (PHQ-2) from the electronic health record.

Results: The cohort …

Characterizing Abdominal Pain In Patients With Gastroparesis, Dylan Vainer, Henry Parkman, Dariush Shahsavari

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

TITLE: CHARACTERIZING ABDOMINAL PAIN IN PATIENTS WITH GASTROPARESIS

AUTHORS (LAST NAME, FIRST NAME): Vainer, Dylan¹; Shahsavari, Dariush²; Parkman, Henry P.²

INSTITUTIONS (ALL): 1. Section of Gastroenterology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States. 2. Temple University Health System Inc, Philadelphia, PA, United States.

ABSTRACT BODY: Introduction: Patients with gastroparesis (Gp) typically present with nausea, vomiting, and early satiety. Abdominal pain can be present in Gp. The cause of abdominal pain in patients with Gp is often unknown. In patients whose predominant symptom is abdominal pain, other causes of abdominal pain …

Lessons Learned From Inspire Super-Performers, Thomas H. Fitzpatrick Iv, Ryan S. Nord

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Objective: The purpose of this study is to examine what demographic factors correlate with greater rates of upper airway stimulation adherence and efficacy.

Study Design: Case control study

Introduction:

Upper airway stimulation (UAS) is emerging as an effective procedure for select patients with obstructive sleep apnea. As initially studied, this procedure is reserved for those exhibiting body mass index (BMI)

Methods:

We queried a single surgeon’s database of UAS cases, totaling 97 at the time of study. The electronic medical record (EMR) was queried for each patient and pertinent demographics were recorded. We began by defining cohorts: super-adherers were …

Antinociceptive Effects Of G-Protein Biased Mu Opioid Receptor Agonists In Male And Female Rats With Chemotherapy-Induced Neuropathy, Tilak Patel Md

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Aim: Mu-opioid receptor (MOR) agonists are often prescribed for the treatment of chemotherapy-induced neuropathy (CIN). Recent drug development strategies have focused on opioids with signaling profiles that “bias” activation of specific intracellular pathways (e.g., G-protein signaling) over others with the aim of increasing therapeutic selectivity. However, it is unknown if the variances in these signaling profiles at the MOR differentially modulate the antinociceptive effects of MOR agonists against neuropathic pain. In the present study, we tested a series of MOR agonists of varying G-protein signaling bias in a rat model of CIN. Methods: CIN was induced in male and female …

Firearm Curriculum For Pediatric Residents Improves Safe Storage Counseling, Hannah Hollon Md, Darina Dinov Do, Benjamin Sandifer Md, Scott Risney Md, Heemali Kamdar Do, Christopher Ferrante Do, Leroy Thacker Phd, Michael S. Ryan Md, Mehp, Elizabeth Wolf Md, Mph

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Objectives

Firearms are the leading cause of death among children and adolescents. Despite evidence to support physician training in firearm safety counseling, formal curricula are limited in pediatric residency programs. We sought to develop and implement a resident-led, feasible, sustainable, and impactful firearm safety curriculum for pediatric residents.

Methods

A firearm safety curriculum was developed by pediatric residents using Kern’s curriculum development framework and delivered to their peers at a single academic center from 2019 - 2020. The three-part series included workshops on basic firearm safety counseling principles, case-based practice, and advocacy training and a gun lock program in collaboration …

Assessing Opportunities To Improve Sedation/Analgesia Use In Neonatal Patients On Ecmo, Rita Hazboun, Prattyak Mukhopadhyay,, Vaneeza Khan, Miheret Yitayew, Nayef Chahin, Nada Darwish, Lisa Shaver, Jie Xu, Thacker Leroy, Karen Hendricks-Munoz

Graduate Medical Education (GME) Resident and Fellow Research Day Posters

Background: Sedation is used during ECMO to prevent agitation. Analgesia is used to dampen pain perception as neonatal procedural pain related stress is associated with later altered neurodevelopment with poorer perceptual reasoning and visual perception. Common sedatives/analgesics used during ECMO are opiates and benzodiazepines. Studies have shown that lipophilic drugs such as Fentanyl and Midazolam are significantly sequestered in the circuit suggesting opportunities to improve delivery for pain.

Hypothesis and Methods: We hypothesized opportunities to improve sedation/analgesia drug treatment in ECMO patients. Using a retrospective analysis of all neonatal patients receiving ECMO between 2015-2020, we aimed to assess the relationship …

Maternal-Fetal Immune Responses In Pregnant Women Infected With Sars-Cov-2, Arya Hanjagi, Arya Revankar, Meghana Sunkara, Tvisha Vanteru

VCU's Medical Journal Club: The Work of Future Health Professionals

This study aimed to provide more insight into how much of an effect these unique maternal-fetal immune responses have during pregnancy and examine the likelihood of placental infections. Pregnant women with positive RT-PCR results for SARS-CoV-2 and healthy gestational age-matched controls made up the study's two primary groups. The study comprised a total of 23 women, 12 women (8 asymptomatic; 1 with mild symptoms; 3 had severe COVID-19 (requiring oxygen supplementation). Sections from the center of the placenta and placental disk were taken and histologically examined. Researchers obtained and analyzed differences in SARS-CoV-2 human maternal peripheral blood, umbilical cord blood, …

Neurod1 Aav-Based Gene Therapy For Functional Brain Repair After Ischemic Injury Through In Vivo Astrocyte-To-Neuron Conversion, Marlena Ramlatchan

VCU's Medical Journal Club: The Work of Future Health Professionals

This study uses AAV based gene therapy to create an astrocyte- neuron conversion to regain functional abilities damaged by ischemic injuries. NeuroD1 treatment has shown promising results in the treatment of ischemic injuries in rodents and is heading towards clinical trials. Cognitive and motor improvements were shown. The basis of this therapy is to use functional glial cells to promote neurocellular growth, which would restore some function lost as a result of injury.

End Stage Recurrent Glioblastoma Treated With A New Noninvasive Non-Contact Oncomagnetic Device, Devam Purohit

VCU's Medical Journal Club: The Work of Future Health Professionals

This presentation focused on the use of a noninvasive oncomagnetic device for glioblastoma. This treatment is special because it is noninvasive and doesn't pose the side effects of chemotherapy or surgery. The study looked at how the oncomagnetic device affected the size of the tumor after it reappeared in the patient's brain after being surgically removed initially. The device was tested on one patient and it was able to reduce his tumor by 31%.

Cauti: Are We Testing Appropriately?, Christoph Lecznar

VCU Health Nursing

Purpose: The purpose of this evidence-based quality improvement project was to decrease catheter associated urinary tract infections in a 28 bed Surgical Trauma Intensive Care Unit in a Level One Trauma Academic Medical Center.

Background: Catheter Associated Urinary Tract Infections (CAUTI) are deemed never events by the Centers for Medicare & Medicaid Services. Centers for Disease Control and Prevention estimates 17-69% of CAUTIs are preventable. Current recommendations for CAUTI reduction include: Education strategies, chlorhexidine gluconate bathing and catheter care, catheter avoidance, policies for insertion, and urine culture testing stewardship. Our unit experienced an increase in CAUTI incidence in May and …

The Emotional Word-Emotional Face Stroop Task In The Abcd Study: Psychometric Validation And Associations With Measures Of Cognition And Psychopathology, Harry R. Smolker, Kai Wang, Monica Luciana, James M. Bjork, Raul Gonzalez, Deanna M. B, Erin C. Mcglade, Roselinde H. Kaiser, Naomi P. Friedman, John K. Hewitt, Marie T. Banich

Psychiatry Publications

Characterizing the interactions among attention, cognitive control, and emotion during adolescence may provide important insights into why this critical developmental period coincides with a dramatic increase in risk for psychopathology. However, it has proven challenging to develop a single neurobehavioral task that simultaneously engages and differentially measures these diverse domains. In the current study, we describe properties of performance on the Emotional Word-Emotional Face Stroop (EWEFS) task in the Adolescent Brain Cognitive Development (ABCD) Study, a task that allows researchers to concurrently measure processing speed/attentional vigilance (i.e., performance on congruent trials), inhibitory control (i.e., Stroop interference effect), and emotional information …

Repeated Exposure To Chlorpyrifos Is Associated With A Dose-Dependent Chronic Neurobehavioral Deficit In Adult Rats, Ana C. R. Ribeiro, Elisa Hawkins, Fay M. Jahr, Joseph L. Mcclay, Laxmikant Deshpande

Neurology Publications

Organophosphate (OP) chemicals include commonly used pesticides and chemical warfare agents, and mechanistically they are potent inhibitors of the cholinesterase (ChE) enzyme. Epidemiological studies report long-term neuropsychiatric issues, including depression and cognitive impairments in OP-exposed individuals. Chlorpyrifos (CPF) is one of the most widely used pesticides worldwide. Multiple laboratory studies have reported on either the long-term behavioral effect of an acute high-dose CPF (30-250 mg/kg) or studied sub-chronic behavioral effects, particularly the motor and cognitive effects of repeated low-dose CPF. However, studies are lacking on chronic mood and depression-related morbidities following repeated CPF doses that would mimic occupationally relevant OP …

Virginia Dental Journal (Vol. 99, No. 1, 2022)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 99, No. 2, 2022)

Virginia Dental Journal

No abstract provided.

Virginia Dental Journal (Vol. 99, No. 3, 2022)

Virginia Dental Journal

No abstract provided.

Violence Prevention Task Force: A Health System’S Journey Towards Zero, Lisa Davis, Denise Holyoak

VCU Health Nursing

VCU Health's mission is to be the safest most caring hospital with zero events of preventable harm to patients, team members, and visitors. Our goal cannot be achieved if our staff suffer from workplace violence injuries thus, our executive leaders sponsored a Violence Task Force in 2017 comprised of leaders and bedside staff from all disciplines to implement evidence-informed strategies to aid in the prevention, response or recovery to a violent event. Review of data and measures of our outcomes are based on our worker's compensation, behavioral rapid response, and safety culture surveys. Event drill-downs are achieved by our post-assault …