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Articles 4351 - 4380 of 5204

Full-Text Articles in Medicine and Health Sciences

Cytoplasmic Filament-Deficient Mutant Of Treponema Denticola Has Pleiotropic Defects, Jacques Izard, William A. Samsonoff, Ronald J. Limberger Nov 2000

Cytoplasmic Filament-Deficient Mutant Of Treponema Denticola Has Pleiotropic Defects, Jacques Izard, William A. Samsonoff, Ronald J. Limberger

Department of Food Science and Technology: Faculty Publications

In Treponema denticola, a ribbon-like structure of cytoplasmic filaments spans the cytoplasm at all stages of the cell division process. Insertional inactivation was used as a first step to determine the function of the cytoplasmic filaments. A suicide plasmid was constructed that contained part of cfpA and a nonpolar erythromycin resistance cassette (ermF and ermAM) inserted near the beginning of the gene. The plasmid was electroporated into T. denticola, and double-crossover recombinants which had the chromosomal copy of cfpA insertionally inactivated were selected. Immunoblotting and electron microscopy confirmed the lack of cytoplasmic filaments. The mutant was further …

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Cognitive Consequences And Central Nervous System Injury Following Treatment For Childhood Leukemia, I. M. Moore, K. A. Espy, P. Kaufmann, J. Kramer, K. Kaemingk, P. Miketova, N. Mollova, M. Kaspar, A. Pasvogel, K. Schram, W. Wara, J. Hutter, K. Matthay Nov 2000

Cognitive Consequences And Central Nervous System Injury Following Treatment For Childhood Leukemia, I. M. Moore, K. A. Espy, P. Kaufmann, J. Kramer, K. Kaemingk, P. Miketova, N. Mollova, M. Kaspar, A. Pasvogel, K. Schram, W. Wara, J. Hutter, K. Matthay

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

OBJECTIVES: To determine the relationship between membrane damage and intellectual and academic abilities in children with acute lymphoblastic leukemia (ALL) and pilot test a math intervention for children with ALL who were affected. DATA SOURCES: Research studies and review articles. CONCLUSIONS: Despite the prophylactic central nervous system (CNS) treatment for long-term disease-free survival, many children with ALL subsequently experience declines in intellectual and academic skills. IMPLICATIONS FOR NURSING PRACTICE: Improving academic abilities in children who have received CNS treatment is of high priority and may have longlasting implications on quality of life.

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Prenatal Cocaine Exposure And Prematurity: Neurodevelopmental Growth, K. A. Espy, D. J. Francis, M. L. Riese Nov 2000

Prenatal Cocaine Exposure And Prematurity: Neurodevelopmental Growth, K. A. Espy, D. J. Francis, M. L. Riese

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

The consequences of prematurity and prenatal cocaine exposure on early neurobehavior and physical growth were examined longitudinally in a sample of 20 cocaine-exposed and 20 nonexposed preterm neonates. The magnitude of the difference in physical growth acceleration related to prenatal cocaine exposure increased with increasing birth gestational age, whereas growth rate differences in irritability decreased. In contrast, prenatal cocaine exposure, independent of prematurity, was related to reduced attention skills at 36 wks conceptional age and increased rates of neurobehavioral change. The effects of prenatal cocaine exposure differed with respect to the degree of prematurity, depending on the nature of the …

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Amino Acid Osmolytes In Regulatory Volume Decrease And Isovolumetric Regulation In Brain Cells: Contribution And Mechanisms, Herminia Pasantes-Morales, Rodrigo Franco, M. Eugenia Torres-Marquez, Karla Hernandez-Fonseca, Arturo Ortega Oct 2000

Amino Acid Osmolytes In Regulatory Volume Decrease And Isovolumetric Regulation In Brain Cells: Contribution And Mechanisms, Herminia Pasantes-Morales, Rodrigo Franco, M. Eugenia Torres-Marquez, Karla Hernandez-Fonseca, Arturo Ortega

School of Veterinary and Biomedical Sciences: Faculty Publications

Brain adaptation to hyposmolarity is accomplished by loss of both electrolytes and organic osmolytes, including amino acids, polyalcohols and methylamines. In brain in vivo, the organic osmolytes account for about 35% of the total solute loss. This review focus on the role of amino acids in cell volume regulation, in conditions of sudden hyposmosis, when cells respond by active regulatory volume decrease (RVD) or after gradual exposure to hyposmotic solutions, a condition where cell volume remains unchanged, named isovolumetric regulation (IVR). The amino acid efflux pathway during RVD is passive and is similar in many respects to the volume-activated anion …

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Method And Apparatus For Adaptive Filtering By Counting Acoustic Sample Zeroes In Ultrasound Imaging, Gregory R. Bashford, Edward D. Nonnweiler, David D. Becker, David John Muzilla Oct 2000

Method And Apparatus For Adaptive Filtering By Counting Acoustic Sample Zeroes In Ultrasound Imaging, Gregory R. Bashford, Edward D. Nonnweiler, David D. Becker, David John Muzilla

Biomedical Imaging and Biosignal Analysis Laboratory

An ultrasound imaging system having an adaptive spatial filter the filter coefficients of which, for particular image parameter sample, are determined by counting the number of neighboring image parameter samples having zero or near-zero values. If the number of zero or near-zero values in a data window is greater than a predetermined threshold, the data in the window is passed, not filtered. This filter has two advantages over other spatial filters. First, image parameter data samples having only zero or near-zero neighboring values (i.e., isolated "point noise") are not smeared. Second, boundaries such as the edge of color in a …

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Clinical, Pathological And Antigenic Aspects Of Bovine Viral Diarrhea Virus (Bvdv) Type 2 Isolates Identified In Brazil, E. F. Flores, L. H. G. V. Gil, S. A. Botton, R. Weiblen, J. F. Ridpath, L. C. Kreutz, C. Pilati, D. Driemeyer, V. Moojen, A. C. Wendelstein Oct 2000

Clinical, Pathological And Antigenic Aspects Of Bovine Viral Diarrhea Virus (Bvdv) Type 2 Isolates Identified In Brazil, E. F. Flores, L. H. G. V. Gil, S. A. Botton, R. Weiblen, J. F. Ridpath, L. C. Kreutz, C. Pilati, D. Driemeyer, V. Moojen, A. C. Wendelstein

School of Veterinary and Biomedical Sciences: Faculty Publications

Nucleotide sequencing and phylogenetic analysis of Brazilian bovine viral diarrhea virus (BVDV) field isolates identified four viruses belonging to the genotype 2. Comparison of 5’ UTR sequences from these isolates to those of North American BVDV type 2 revealed genomic variations that correlated with the geographic origins of the isolates. Two of the Brazilian type 2 viruses were isolated from clinical cases of gastroenteric/respiratory disease and two were isolated from healthy bovine fetuses. The clinical cases affected young animals (8- and 18-months-old) and were characterized by diarrhea, respiratory signs, extensive oral and digestive tract erosions, conjunctival and vulvar congestion, occasional …

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Analysis Of 200 Food Items For Benzo[A]Pyrene And Estimation Of Its Intake Ίη An Epidemiologic Study, Ν. Kazerouni, R. Sinha, Che-Han Hsu, Α. Greenberg, Ν. Rothman Oct 2000

Analysis Of 200 Food Items For Benzo[A]Pyrene And Estimation Of Its Intake Ίη An Epidemiologic Study, Ν. Kazerouni, R. Sinha, Che-Han Hsu, Α. Greenberg, Ν. Rothman

United States Public Health Resources

Animal stιιdies have shown that dietary intake of benzo[α]pyrene (BaP), a polycyclic aromatic hydrocarbon (ΡΑΗ), causes increased levels of tumors at several sites, particιιlarly ίη the upper gastrointestinal tract. However, the role of dietary intake of BaP and cancer ίη humans is not clear. We CIeated a BaP database of selected food products that could be lίnl(ed to Food Frequency Qnestionnaires (FFQs) to estimate BaP intake. BaP levels were measnred for each food line-item (composite samples) which consisted of a variety of foods ίη a FFQ. Composite sample parts were derived from the Second National Health and Nutrition Examination Survey …

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Prevalence Of Non-O157:H7 Shiga Toxin-Producing Escherichia Coli In Diarrheal Stool Samples From Nebraska, Paul Fey, R. S. Wickert, M.E. Rupp, T. J. Safranek, S. H. Hinrichs Oct 2000

Prevalence Of Non-O157:H7 Shiga Toxin-Producing Escherichia Coli In Diarrheal Stool Samples From Nebraska, Paul Fey, R. S. Wickert, M.E. Rupp, T. J. Safranek, S. H. Hinrichs

United States Public Health Resources

We determined the prevalence of Shiga toxin-producing Escherichia coli (STEC) in diarrheal stool samples from Nebraska by three methods: cefixime-tellurite sorbitol MacConkey (CT-SMAC) culture, enterohemorrhagic E. coli (EHEC) enzyme immunoassay, and stx1,2 polymerase chain reaction (PCR). Fourteen (4.2%) of 335 specimens were positive by at least one method (CT-SMAC culture [6 of 14], EHEC enzyme immunoassay [13 of 14], stx1,2 PCR [14 of 14]). Six contained serogroup 0157, while non-0157 were as prevalent as 0157 serogroups.

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Hsv Latency-Associated Transcript And Neuronal Apoptosis, Anthony B. Nesburn, Clinton J. Jones Sep 2000

Hsv Latency-Associated Transcript And Neuronal Apoptosis, Anthony B. Nesburn, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Thompson and Sawtell report that the Promega Anti-PARP p85 antibody did not recognize cleaved PARP in mouse or rabbit cells in their experiments, and conclude that the results reported with this antibody by Perng et al. (1) are an artifact. The Promega antibody was generated against a peptide based on the sequence of human p85. Although the corresponding bovine sequence differs by two amino acids, the antibody reacts with both human and bovine p85 (2). The mouse and rat sequences for this region of p85 differ from the human sequence by a single amino acid that corresponds to one of …

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Intestinal Lesions Caused By A Strain Of Chlamydia Suis In Weanling Pigs Infected At 21 Days Of Age, Douglas G. Rogers, Arthur A. Andersen Sep 2000

Intestinal Lesions Caused By A Strain Of Chlamydia Suis In Weanling Pigs Infected At 21 Days Of Age, Douglas G. Rogers, Arthur A. Andersen

School of Veterinary and Biomedical Sciences: Faculty Publications

The objective of this study was to determine whether a strain of Chlamydia suis shown previously to be an intestinal pathogen in gnotobiotic piglets could cause diarrhea and intestinal lesions in young weanling pigs. Pigs from 2 sows were randomly assigned to 2 groups. Group 1 included 13 pigs that were weaned at 24 hours of age and then housed in isolator units and fed milk replacer and unmedicated starter ration. Group 2 included 8 pigs that nursed their respective sows, consumed unmedicated starter ration, and were weaned at 21 days of age. Ten pigs in group 1 and 6 …

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Cancer Surveillance Series: Non-Hodgkin’S Lymphoma Incidence By Histologic Subtype In The United States From 1978 Through 1995, Frank D. Groves, Martha S. Linet, Lois B. Travis, Susan S. Devesa Aug 2000

Cancer Surveillance Series: Non-Hodgkin’S Lymphoma Incidence By Histologic Subtype In The United States From 1978 Through 1995, Frank D. Groves, Martha S. Linet, Lois B. Travis, Susan S. Devesa

United States Public Health Resources

Background: Clinical investigations have shown prognostic heterogeneity within the non-Hodgkin’s lymphomas (NHLs) according to histology, but few descriptive studies have considered NHLs by subgroup. Our purpose is to assess the demographic patterns and any notable increases in population- based rates of different histologic subgroups of NHL.
Methods: Using data collected by the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute, we calculated incidence rates for the major clinicopathologic categories of NHL by age, race, sex, geographic area, and time period.
Results: Among the 60 057 NHL cases diagnosed during the period from 1978 through 1995, total incidence …

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Social Anxiety Scale For Adolescents: Normative Data And Further Evidence Of Construct Validity, Heidi M. Inderbitzen-Nolan, Kenneth S. Walters Aug 2000

Social Anxiety Scale For Adolescents: Normative Data And Further Evidence Of Construct Validity, Heidi M. Inderbitzen-Nolan, Kenneth S. Walters

Department of Psychology: Faculty Publications

Replicates and extends prior work with the Social Anxiety Scale for Adolescents (SAS– A) by providing psychometric data, further evidence of construct validity, and largesample based normative data. Participants were 2,937 students (1,431 boys and 1,506 girls) in Grades 6, 7, 8, 9, and 11. Students completed the SAS–A, the Revised Children’s Manifest Anxiety Scale (RCMAS), and the Children’s Depression Inventory (CDI). Results replicated a three-factor structure for the SAS–A, with good internal consistencies for its subscales. Normative data were subdivided by sex and grade group. Construct validity included replication of prior relations with general anxiety (RCMAS) and depressive symptomatology …

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Naturally Occurring Tuberculosis In White-Tailed Deer, Mitchell V. Palmer, Diana L. Whipple, Janet B. Payeur, David P. Alt, Kevin J. Esch, Colleen S. Bruning-Fann, John B. Kaneene Jun 2000

Naturally Occurring Tuberculosis In White-Tailed Deer, Mitchell V. Palmer, Diana L. Whipple, Janet B. Payeur, David P. Alt, Kevin J. Esch, Colleen S. Bruning-Fann, John B. Kaneene

Michigan Bovine Tuberculosis Bibliography and Database

Objective—To determine the distribution of lesions and extent of tissues infected with Mycobacterium bovis in a captive population of white-tailed deer.

Design—Cross-sectional study.

Animals—116 captive white-tailed deer.

Procedure—Deer were euthanatized, and postmortem examinations were performed. Tissues with gross lesions suggestive of tuberculosis were collected for microscopic analysis and bacteriologic culture. Tissues from the head, thorax, and abdomen of deer with no gross lesions were pooled for bacteriologic culture. Tonsillar, nasal, oral, and rectal swab specimens, fecal samples, and samples of hay and pelleted feed, soil around feeding sites, and water from 2 natural ponds were collected …

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Method And Apparatus For Controlling Acoustic Signal Bandwidth In An Ultrasonic Diagnostic Imaging System, Jeffrey R. Resnick, Gregory R. Bashford Jun 2000

Method And Apparatus For Controlling Acoustic Signal Bandwidth In An Ultrasonic Diagnostic Imaging System, Jeffrey R. Resnick, Gregory R. Bashford

Biomedical Imaging and Biosignal Analysis Laboratory

An ultrasonic imaging system includes a receive beamformer that generates analog receive signals and a scan converter. A receive signal processing path interconnects the receive beamformer and the scan converter, and this processing path included both an A/D converter characterized by a selectable sampling rate and at least one filter characterized by at least one filter parameter. The filter parameter is selected as a function of the sampling rate to provide enhanced image quality.

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One-Trial Context Fear Conditioning With Immediate Shock: The Roles Of Transport And Contextual Cues, Rick A. Bevins, Anthony S. Rauhut, Janice E. Mcphee, John J. B. Ayres Jun 2000

One-Trial Context Fear Conditioning With Immediate Shock: The Roles Of Transport And Contextual Cues, Rick A. Bevins, Anthony S. Rauhut, Janice E. Mcphee, John J. B. Ayres

Department of Psychology: Faculty Publications

In three experiments, using a total of 120 albino rats, we assessed whether transportation cues might evoke some of the freezing (i.e., defensive immobility) that we see in a context on a day following a footshock given immediately after placement in that context. The results suggested that immediate shock could directly condition strong fear to both simulated and actual transport cues. Although conditioning to transport cues explains some of the freezing that is seen on the test day, it does not explain all of it. We also found evidence that some of the freezing is due to conditioning to permanent …

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Anticipating Adulthood: Expected Timing Of Work And Family Transitions Among Rural Youth, Lisa J. Crockett, C. Raymond Bingham Jun 2000

Anticipating Adulthood: Expected Timing Of Work And Family Transitions Among Rural Youth, Lisa J. Crockett, C. Raymond Bingham

Department of Psychology: Faculty Publications

This study examined family and individual processes influencing the future expectancies of adolescents (N = 345) from an economically stressed rural community. The anticipated timing and sequencing of key role transitions (school completion, job entry, marriage, and parenthood) were examined for each gender. In addition, factors contributing to individual differences in expected timing were examined, and gender differences in predictors were tested. Results indicated that rural adolescents' expectancies about adult role transitions diverged somewhat from societal norms with respect to timing. Family background and relationships, adolescents' attitudes and behaviors, and educational aspirations all contributed to individual differences in expected …

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Parental Monitoring And Adolescent Adjustment: An Ecological Perspective, Kristen C. Jacobson, Lisa J. Crockett Jun 2000

Parental Monitoring And Adolescent Adjustment: An Ecological Perspective, Kristen C. Jacobson, Lisa J. Crockett

Department of Psychology: Faculty Publications

This study uses an ecological framework to examine the associations between parental monitoring and a variety of indicators of adolescent adjustment. Specifically, investigators examined whether higher levels of parental monitoring were associated with higher adolescent grade point average, lower levels of adolescent depression, and lower levels of adolescent sexual activity and minor delinquency, and whether these relations were moderated by gender, grade level, or mothers’ work status. Participants were 424 7th to 12th graders from a single rural school district in central Pennsylvania. Bivariate correlations indicated that parental monitoring had strong associations with all indicators of adjustment for both boys …

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"Preface" To Negotiating Adolescence In Times Of Social Change, Lisa J. Crockett, Rainer K. Silbereisen Jun 2000

"Preface" To Negotiating Adolescence In Times Of Social Change, Lisa J. Crockett, Rainer K. Silbereisen

Department of Psychology: Faculty Publications

In February 1996, a diverse group of social scientists (psychologists, sociologists, and anthropologists) from Germany, the United Kingdom, and the United States convened at the Pennsylvania State University to discuss the ways in which social change may affect adolescent development, the likely consequences for adolescent functioning and well-being, and the kinds of social interventions needed to support healthy development in a changing society. Entitled "Negotiating Adolescence in Times of Social Change," the conference was organized to consider the abrupt and more gradual social changes affecting Western industrialized countries. Drawing on the ecological and life course perspectives, we were especially interested …

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Rural Youth: Ecological And Life Course Perspectives, Lisa J. Crockett, Michael J. Shanahan, Julia Jackson-Newsom Jun 2000

Rural Youth: Ecological And Life Course Perspectives, Lisa J. Crockett, Michael J. Shanahan, Julia Jackson-Newsom

Department of Psychology: Faculty Publications

Drawing on the themes of social change, ecological risk, and their implications for the life course, this chapter is intended as a point of departure for future research on rural adolescents. We begin by considering the basic but difficult issue of defining the ecology of rural youth, noting possible sources of risk and resilience. We then examine research on psychosocial adjustment among rural youth, identifying how they are advantaged and disadvantaged relative to other youth. Third, we turn to a central challenge facing contemporary rural youth: the need to reconcile attachments to family and place with a desire for educational …

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Social Change And Adolescent Development: Issues And Challenges, Lisa J. Crockett, Rainer K. Silbereisen Jun 2000

Social Change And Adolescent Development: Issues And Challenges, Lisa J. Crockett, Rainer K. Silbereisen

Department of Psychology: Faculty Publications

Determining the consequences of such societal-level changes for adolescent development presents formidable challenges. Social change on one or more dimensions must be documented, the complex processes through which social change may affect adolescents must be identified, and the hypothesized causal processes must be linked empirically to adolescent outcomes. In this chapter, we discuss these challenges and the conceptual issues they raise. We begin with one example of social change and use it as a springboard for discussing four questions:
1. What kinds of contextual changes are produced by social change?
2. How (through what mediating processes) do these changes affect …

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Efflux Of Osmolyte Amino Acids During Isovolumic Regulation In Hippocampal Slices, Rodrigo Franco, Octavio Quesada, Herminia Pasantes-Morales May 2000

Efflux Of Osmolyte Amino Acids During Isovolumic Regulation In Hippocampal Slices, Rodrigo Franco, Octavio Quesada, Herminia Pasantes-Morales

School of Veterinary and Biomedical Sciences: Faculty Publications

The efflux of potassium (K+) and amino acids from hippocampal slices was measured after sudden exposure to 10% (270 mOsm), 25% (225 mOsm) or 50% (150 mOsm) hyposmotic solutions or after gradual decrease (22.5 mOsm/min) in external osmolarity. In slices suddenly exposed to 50% hyposmotic solutions, swelling was followed by partial (74%) cell volume recovery, suggesting regulatory volume decrease (RVD). With gradual hyposmotic changes, no increase in cell water content was observed even when the solution at the end of the experiment was 50% hyposmotic, showing the occurrence of isovolumic regulation (IVR). The gradual decrease in osmolarity elicited …

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Ceftriaxone-Resistant Salmonella Infection Acquired By A Child From Cattle, Paul D. Fey, Thomas J. Safranek, Mark E. Rupp, Eileen F. Dunne, Efrain Ribot, Peter C. Iwen, Patricia A. Bradford, Frederick J. Angulo, Steven H. Hinrichs Apr 2000

Ceftriaxone-Resistant Salmonella Infection Acquired By A Child From Cattle, Paul D. Fey, Thomas J. Safranek, Mark E. Rupp, Eileen F. Dunne, Efrain Ribot, Peter C. Iwen, Patricia A. Bradford, Frederick J. Angulo, Steven H. Hinrichs

Zoonotics and Wildlife Disease: Publications

Background
The emergence of resistance to antimicrobial agents within the salmonellae is a worldwide problem that has been associated with the use of antibiotics in livestock. Resistance to ceftriaxone and the fluoroquinolones, which are used to treat invasive salmonella infections, is rare in the United States. We analyzed the molecular characteristics of a ceftriaxone-resistant strain of Salmonella enterica serotype typhimurium isolated from a 12-year-old boy with fever, abdominal pain, and diarrhea.
Methods
We used pulsed-field gel electrophoresis and analysis of plasmids and β-lactamases to compare the ceftriaxone-resistant S. enterica serotype typhimurium from the child with four isolates of this strain …

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Choosing A Doctor: An Exploratory Study Of Factors Influencing Patients’ Choice Of A Primary Care Doctor, Brian H. Bornstein, David Marcus, William Cassidy Apr 2000

Choosing A Doctor: An Exploratory Study Of Factors Influencing Patients’ Choice Of A Primary Care Doctor, Brian H. Bornstein, David Marcus, William Cassidy

Department of Psychology: Faculty Publications

We assessed the relative importance healthcare consumers attach to various factors in choosing a primary care doctor (PCD) in a cross-sectional, in-person survey. Three survey locations were used: doctors’ offices, a public shopping area, and meetings of a women’s organization. A total of 636 community residents, varying across major demographic categories, participated. Participants completed a 23-item survey, designed to assess which factors consumers perceive as most relevant in choosing a PCD. Participants perceived professionally relevant factors (e.g. whether the doctor is board certified, office appearance) and management practices (e.g. time to get an appointment, evening and weekend hours) as more …

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Method And Apparatus For Three-Dimensional Ultrasound Imaging Of Biopsy Needle, Syed Omar Ishrak, Mir Said Seyed-Bolorforosh, William Thomas Hatfield, Todd Michael Tillman, Brian Peter Geiser, Gregory R. Bashford, Michael Joseph Washburn Apr 2000

Method And Apparatus For Three-Dimensional Ultrasound Imaging Of Biopsy Needle, Syed Omar Ishrak, Mir Said Seyed-Bolorforosh, William Thomas Hatfield, Todd Michael Tillman, Brian Peter Geiser, Gregory R. Bashford, Michael Joseph Washburn

Biomedical Imaging and Biosignal Analysis Laboratory

A method and an apparatus for three-dimensional ultrasound imaging of a needle-like instrument, such as a biopsy needle, inserted in a human body. The instrument is visualized by transmitting ultrasound beams toward the instrument and then detecting the echo signals using a linear array of transducer elements. The problem of ultrasound being reflected from a biopsy needle in a direction away from the transducer array is solved by steering the transmitted ultrasound beams t increase the angle at which the beams impinge upon the biopsy needle. Ideally the ultrasound beams are perpendicular to the needle. This increases the system's sensitivity …

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Drugs In The Heartland: Methamphetamine Use In Rural Nebraska, Denise C. Herz Apr 2000

Drugs In The Heartland: Methamphetamine Use In Rural Nebraska, Denise C. Herz

United States Public Health Resources

A decade ago, methamphetamine was commonly believed to be limited to the West Coast and a few other, isolated areas. Recent evidence shows that substantial proportions of arrestees in several large urban areas of the West and Midwest are using the drug. Increasingly, the problem is coming to the attention of policymakers and law enforcement nationwide. (See “The Federal Government Responds.”)
Methamphetamine has generated concern because of its ready availability and the severity of its effects on the user. It is cheaper than cocaine, it is easy to manufacture, it produces a longer lasting “high,” and its short- and long-term …

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Genetic Resistance To Experimental Infection With In Red Deer (Cervus Elaphus), Colin G. Mackintosh, Tariq Qureshi, Ken Waldrup, Robert E. Labes, Ken G. Dodds, J. Frank T. Griffin Mar 2000

Genetic Resistance To Experimental Infection With In Red Deer (Cervus Elaphus), Colin G. Mackintosh, Tariq Qureshi, Ken Waldrup, Robert E. Labes, Ken G. Dodds, J. Frank T. Griffin

Michigan Bovine Tuberculosis Bibliography and Database

Tuberculosis (Tb) caused by Mycobacterium bovis is a worldwide threat to livestock and humans. One control strategy is to breed livestock that are more resistant to Mycobacterium bovis. In a 3-year heritability study 6 farmed red deer stags were selected from 39 on the basis of their differing responses to experimental challenge via the tonsillar sac with approximately 500 CFU of M. bovis. Two stags remained uninfected, two were moderately affected, and two developed serious spreading Tb. Seventy offspring, bred from these six stags by artificial insemination using stored semen, were similarly challenged with M. bovis …

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Proceedings From The Conference On Bovine Tuberculosis – March 2000 Mar 2000

Proceedings From The Conference On Bovine Tuberculosis – March 2000

Michigan Bovine Tuberculosis Bibliography and Database

Table of Contents:

The Challenge, USDA by Craig Reed, DVM; John Clifford, DVM

The Comprehensive Strategic Plan by Joe VanTiem, DVM, MS

Surveillance of Non-Cervid (Cattle and Goats) Livestock by Nathan Zauel, DVM

Surveillance of Bovine Tuberculosis in Michigan Captive Cervidae Mike VanderKlok, DVM Surveillance of Domestic Carnivores for Tuberculosis Steven L. Halstead, DVM, MS Human Health Update: Bovine Tuberculosis in Michigan by Barbara Robinson-Dunn, PhD; Mary Grace Stobierski, DVM, MPH

Risks Associated with M. bovis in Michigan Free-ranging White-tailed Deer by Barbara Corso, DVM, MS

Economic Impact of Wildlife-Related Recreation in the 5-County Area: An Update by Dennis Propst, …

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Serum Lipid Response To N-3 Fatty Acid Enriched Eggs In Persons With Hypercholesterolemia, Nancy M. Lewis, Kim Schalch, Sheila E. Scheideler Mar 2000

Serum Lipid Response To N-3 Fatty Acid Enriched Eggs In Persons With Hypercholesterolemia, Nancy M. Lewis, Kim Schalch, Sheila E. Scheideler

Department of Nutrition and Health Sciences: Faculty Publications

Consumption of long-chain n-3 polyunsaturated fatty acids (n-3 PUFA) is low among certain population subgroups in the United States, especially in people living in Midwestern states and those who dislike fish. Therefore, there is a need to identify acceptable food sources of n-3 PUFA. Vegetable oils, such as canola and soy, provide some n-3 fatty acids. However, these sources are high in n-6 fatty acids and there is concern that they may have detrimental side effects. Eggs enriched in n-3 PUFA can be produced by incorporating sources of these fatty acids into poultry rations. In acceptability studies, US consumers responded …

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Virus-Induced Neuronal Apoptosis Blocked By The Herpes Simplex Virus Latency-Associated Transcript, Guey-Chuen Perng, Clinton J. Jones, Janice Ciacci-Zanella, Melissa Stone, Gail A. Henderson, Ada Yukht, Susan M. Slanina, Florence M. Hofman, Homayon Ghiasi, Anthony B. Nesburn, Steven L. Wechsler Feb 2000

Virus-Induced Neuronal Apoptosis Blocked By The Herpes Simplex Virus Latency-Associated Transcript, Guey-Chuen Perng, Clinton J. Jones, Janice Ciacci-Zanella, Melissa Stone, Gail A. Henderson, Ada Yukht, Susan M. Slanina, Florence M. Hofman, Homayon Ghiasi, Anthony B. Nesburn, Steven L. Wechsler

School of Veterinary and Biomedical Sciences: Faculty Publications

Latent infections with periodic reactivation are a common outcome after acute infection with many viruses. The latency-associated transcript (LAT) gene is required for wild-type reactivation of herpes simplex virus (HSV). However, the underlying mechanisms remain unclear. In rabbit trigeminal ganglia, extensive apoptosis occurred with LAT- virus but not with LAT+ viruses. In addition, a plasmid expressing LAT blocked apoptosis in cultured cells. Thus, LAT promotes neuronal survival after HSV-1 infection by reducing apoptosis.

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The Suggestibility Of Older Witnesses, Brian H. Bornstein, Christy J. Witt, Katie E. Cherry, Edith Greene Feb 2000

The Suggestibility Of Older Witnesses, Brian H. Bornstein, Christy J. Witt, Katie E. Cherry, Edith Greene

Department of Psychology: Faculty Publications

The present study compares younger and older adult witnesses’ susceptibility to misinformation. Previous research on the misinformation effect has not measured the relationship between the effect and individuals’ perceptions of their own memory abilities. Such perceptions, and general knowledge of one’s own memory processes, are referred to as “metamemory.” In order to examine the relationship between metamemory and the misinformation effect in the present study, participants also completed a questionnaire that assessed their perception of their memory functioning. Although older persons tend to perceive their memories as being faulty, the correlation between self-assessment of memory abilities and actual memory performance …

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