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Articles 4201 - 4230 of 5204
Full-Text Articles in Medicine and Health Sciences
Effectiveness Of Nutrition Counseling In Young Adult Males, D. R. Williams, Nancy M. Lewis
Effectiveness Of Nutrition Counseling In Young Adult Males, D. R. Williams, Nancy M. Lewis
Department of Nutrition and Health Sciences: Faculty Publications
The purpose of this project was to determine if the addition of a laboratory measurement, i.e., measurement of serum cholesterol, would increase the effectiveness of nutrition counseling in young men. Subjects were a random sample of 45 healthy male students from a Midwestern university, between the ages of 20 and 25 who were consuming >30% of kcal from fat. Men were randomly assigned to one of four groups; nutrition counseling and measurement of serum cholesterol (NC + SC), nutrition counseling only (NC), measurement of serum cholesterol only (SC), or control (C). At weeks 1 and 6, participants completed a 24-hour …
Challenges, Strategies, And Tools For Research Scientists: Using Web-Based Information Resources, Danielle Bodrero Hoggan
Challenges, Strategies, And Tools For Research Scientists: Using Web-Based Information Resources, Danielle Bodrero Hoggan
E-JASL: Electronic Journal of Academic and Special Librarianship (1999-2009, Volumes 1-10)
Scientists face many challenges in harnessing web-based resources. Information overload, misinformation, fees, poorly designed navigation, and loss of browsability all hamper the scientist searcher. In addition, many scientists rely on only one or two databases and often miss unique information that is available through other sources. Librarians can team up with scientists to develop strategies to overcome the challenges of web-based information. For example, a librarian can teach effective information seeking techniques, including how to use controlled vocabularies, how to evaluate information on the web, and how to complement web-based resources with print resources. Librarians can also help scientists to …
Reducing Childhood Pedestrian Injuries: Individual Risk Factors (Chapter 3), Katherine Kaufer Christoffel, Lizette Peterson, David Dilillo
Reducing Childhood Pedestrian Injuries: Individual Risk Factors (Chapter 3), Katherine Kaufer Christoffel, Lizette Peterson, David Dilillo
Department of Psychology: Faculty Publications
Most factors influencing the risk of pedestrian injury for children are based on family considerations or community norms, not on individuals. Nevertheless, individual risk factors should be considered when planning prevention programs (Christoffel, Donovan et al. 1996). The potential importance of individual traits has been extensively studied in the hope of finding a factor that could be modified. Considerations of the individual are important because they largely define the child’s risk of injury, even while walking with others. The causal sequence of a child walking to a particular site at a particular time where he or she is injured is …
In-Home Prenatal Nutrition Intervention Increased Dietary Iron Intakes And Reduced Low Birthweight In Low-Income African-American Women, Chiquita Briley, Nicole L. Flanagan, Nancy M. Lewis
In-Home Prenatal Nutrition Intervention Increased Dietary Iron Intakes And Reduced Low Birthweight In Low-Income African-American Women, Chiquita Briley, Nicole L. Flanagan, Nancy M. Lewis
Department of Nutrition and Health Sciences: Faculty Publications
Low birthweight (LBW), defined as an infant weighing less than 2,500 grams (1), is a major determinant of infant mortality and contributes to infant and childhood morbidity and increased healthcare costs (2-4). LBW occurs due to preterm delivery (length of gestation less than 37 weeks), growth retardation, or both (2). In the United States, higher rates of LBW occur in urban areas with high concentrations of low-income ethnic minorities (5). Results of the 1997 Pediatric Nutrition Surveillance indicate that the rate of LBW in the United States was 13% for African-American infants, and 8% for whites (6). Healthy People 2010 …
A Mutation In The Latency-Related Gene Of Bovine Herpesvirus 1 Disrupts The Latency Reactivation Cycle In Calves, Melissa Inman, Luciane Lovato, Alan R. Doster, Clinton J. Jones
A Mutation In The Latency-Related Gene Of Bovine Herpesvirus 1 Disrupts The Latency Reactivation Cycle In Calves, Melissa Inman, Luciane Lovato, Alan R. Doster, Clinton J. Jones
School of Veterinary and Biomedical Sciences: Faculty Publications
Bovine herpesvirus 1 (BHV-1) is an important pathogen of cattle, and infection is usually initiated via the ocular or nasal cavity. Following acute infection, the primary site for BHV-1 latency is the sensory neuron. Reactivation from latency occurs sporadically, resulting in virus shedding and transmission to uninfected cattle. The only abundant viral transcript expressed during latency is the latency-related (LR) RNA, suggesting that it mediates some aspect of latency. An LR mutant was constructed by inserting three stop codons near the beginning of the LR-RNA, suggesting that expression of LR proteins would be altered. The LR mutant grew with wild-type …
Phylogenetic Analysis Of Brazilian Bovine Viral Diarrhea Virus Type 2 (Bvdv-2) Isolates: Evidence For A Subgenotype Within Bvdv-2, Eduardo F. Flores, Julia F. Ridpath, Rudi Weiblen, Fernanda S. F. Vogel, Laura H.V.G. Gil
Phylogenetic Analysis Of Brazilian Bovine Viral Diarrhea Virus Type 2 (Bvdv-2) Isolates: Evidence For A Subgenotype Within Bvdv-2, Eduardo F. Flores, Julia F. Ridpath, Rudi Weiblen, Fernanda S. F. Vogel, Laura H.V.G. Gil
School of Veterinary and Biomedical Sciences: Faculty Publications
Phylogenetic analysis divides bovine viral diarrhea viruses (BVDV) into two different genotypes (BVDV1 and BVDV2). BVDV1 strains have been further subdivided into two to 11 subgenotypes. Phylogenetic analysis of BVDV2 isolates, however, has not been able to identify discrete subgenotypes. In this study, we identified six South American BVDV2 strains and one North American BVDV2 strain that cluster to a separate genetic group within BVDV2, thus representing a distinct subgenotype. The 5’ untranslated region (UTR) sequence homology between these six strains and other BVDV2 from North America, Europe and Asia (81.7%) is lower than the homology used to segregate BVDV1 …
The Need For Proximal Mechanisms To Understand Individual Differences In Altruism, Gustavo Carlo, Rick A. Bevins
The Need For Proximal Mechanisms To Understand Individual Differences In Altruism, Gustavo Carlo, Rick A. Bevins
Department of Psychology: Faculty Publications
An "Open Peer Commentary" on the article "Altruism and selfishness" by Howard Rachlin.
There are three concerns regarding Rachlin’s altruism model. First, proximal causal mechanisms such as those identified by cognitive neuroscientists and behavioral neuropharmacologists are not emphasized. Second, there is a lack of clear testable hypotheses. And third, extreme forms of altruism are emphasized rather than common forms. We focus on an overarching theme – proximal mechanisms of individual differences in altruism.
Would Smokers With Schizophrenia Benefit From A More Flexible Approach To Smoking Treatment?, Dennis E. Mcchargue, Susy B. Gulliver, Brian Hitsman
Would Smokers With Schizophrenia Benefit From A More Flexible Approach To Smoking Treatment?, Dennis E. Mcchargue, Susy B. Gulliver, Brian Hitsman
Department of Psychology: Faculty Publications
We evaluated literature that addresses the notion that flexible smoking treatment approaches are warranted for smokers with a diagnosis of schizophrenia. Understanding the biological and psychological mechanisms that increase the likelihood of smoking and decrease the motivation to quit for these individuals is addressed within the framework of a neurobiological model. We provide a brief overview of the limited smoking cessation treatment literature for patients with schizophrenia and compare abstinence-focused versus reduction-focused treatment modalities. The potential utility of the reduction-focused approach to tobacco treatment for these smokers is evaluated. Suggestions for future research to address the utility and efficacy of …
Factors Influencing Children To Self-Disclose Sexual Abuse, Mary L. Paine, David J. Hansen
Factors Influencing Children To Self-Disclose Sexual Abuse, Mary L. Paine, David J. Hansen
Department of Psychology: Faculty Publications
Self-disclosure by victims of child sexual abuse (CSA) is critical to initiate legal and therapeutic intervention. Unfortunately, research indicates that lengthy delays in disclosure and even nondisclosure are common. A comprehensive review of the clinical and research literature on CSA and an overview of related bodies of literature was conducted. Areas addressed include the context of sexual abuse as it relates to disclosure, the context and elements of children’s disclosures, motivational factors inhibiting disclosure, and models of the disclosure process. Ancillary and analogue research on secrecy and disclosure are also reviewed. Implications for future research and practice are discussed.
What Do We Assess When We Assess A Big 5 Trait? : A Content Analysis Of The Affective, Behavioral, And Cognitive Processes Represented In Big 5 Personality Inventories, Lisa M. Pytlik Zillig, Scott H. Hemenover, Richard A. Dienstbier
What Do We Assess When We Assess A Big 5 Trait? : A Content Analysis Of The Affective, Behavioral, And Cognitive Processes Represented In Big 5 Personality Inventories, Lisa M. Pytlik Zillig, Scott H. Hemenover, Richard A. Dienstbier
Department of Psychology: Faculty Publications
What are personality traits? Are all “broad” traits equally broad in the constructs they encompass and in the pervasiveness of their effects? Or are some traits more or less affective, behavioral, or cognitive in nature? The present study examined these issues as they applied to the Big 5 traits of Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness. Expert and novice raters judged the extent to which items from four popular Big 5 inventories contain behavioral, cognitive, or affective components. Traits and inventories were then compared in terms of their relative assessment of these components. Results indicate convergence among inventories but remarkable …
Too Many Of A Good Thing? The Effects Of Multiple Motivations On Stress, Cost, Fulfillment, And Satisfaction , Marc T. Kiviniemi, Mark Snyder, Allen M. Omoto
Too Many Of A Good Thing? The Effects Of Multiple Motivations On Stress, Cost, Fulfillment, And Satisfaction , Marc T. Kiviniemi, Mark Snyder, Allen M. Omoto
Department of Psychology: Faculty Publications
Individuals engage in behaviors to satisfy motivations and can engage in the same behavior to satisfy a variety of different motivations. Previous research has examined how differences in the overall amount of motivation influence outcomes but has not addressed how differences in the number of conceptually distinct motivations one has for a particular action influence outcomes. In two longitudinal field studies, individuals with more than one motivation for volunteering experienced greater negative outcomes than did those who volunteered to satisfy a single motivation. A laboratory study manipulated the number of motivations individuals had for engaging in a volunteer activity. Individuals …
Effect Of Non-Nicotinic Moist Snuff Replacement And Lobeline On Withdrawal Symptoms During 48-H Smokeless Tobacco Deprivation, Dennis E. Mcchargue, Frank L. Collins Jr., Lee M. Cohen
Effect Of Non-Nicotinic Moist Snuff Replacement And Lobeline On Withdrawal Symptoms During 48-H Smokeless Tobacco Deprivation, Dennis E. Mcchargue, Frank L. Collins Jr., Lee M. Cohen
Department of Psychology: Faculty Publications
The present study investigated the effects of two herbal components (BACCOFFTM and DIPSTOP ™) of a commercially available smokeless tobacco treatment program for reducing subjective withdrawal symptoms during deprivation. One component, BACCOFF™, is a non-nicotinic chew. The second component, DIPSTOP™, is a liquid containing the alkaloid lobeline, which to some extent mimics peripheral nicotinic effects. All participants (N = 22 males) were placed in four conditions: BACCOFF™ + DIPSTOP™, BACCOFF™ + placebo control, DIPSTOP™ only, and placebo control only. The conditions involved 48 h of deprivation, and subjects were exposed to one condition per week for 4 weeks. …
Isolation And Characterization Of Endophytic Colonizing Bacteria From Agronomic Crops And Prairie Plants, Denise K. Zinniel, Patricia A. Lambrecht, N. Beth Harris, Zhengyu Feng, Daniel Kuczmarski, Phyllis Higley, Carol A. Ishimaru, Alahari Arunakumari, Raul G. Barletta, Anne K. Vidaver
Isolation And Characterization Of Endophytic Colonizing Bacteria From Agronomic Crops And Prairie Plants, Denise K. Zinniel, Patricia A. Lambrecht, N. Beth Harris, Zhengyu Feng, Daniel Kuczmarski, Phyllis Higley, Carol A. Ishimaru, Alahari Arunakumari, Raul G. Barletta, Anne K. Vidaver
School of Veterinary and Biomedical Sciences: Faculty Publications
Endophytic bacteria reside within plant hosts without causing disease symptoms. In this study, 853 endophytic strains were isolated from aerial tissues of four agronomic crop species and 27 prairie plant species. We determined several phenotypic properties and found approximately equal numbers of gram-negative and gram-positive isolates. In a greenhouse study, 28 of 86 prairie plant endophytes were found to colonize their original hosts at 42 days postinoculation at levels of 3.5 to 7.7 log10 CFU/g (fresh weight). More comprehensive colonization studies were conducted with 373 corn and sorghum endophytes. In growth room studies, none of the isolates displayed pathogenicity, …
Composition And Method For The Prevention And Treatment Of Oxidative Damage In Ocular Tissues, Marjorie F. Lou, Nalini Raghavachari;, Fengyu Qiao
Composition And Method For The Prevention And Treatment Of Oxidative Damage In Ocular Tissues, Marjorie F. Lou, Nalini Raghavachari;, Fengyu Qiao
School of Veterinary and Biomedical Sciences: Faculty Publications
Thioltransferase and derivatives thereof are provided. Methods of treating or preventing cataract formation comprosing administering thioltransferase or a derivative thereof are also provided. Thioltransferase or derivatives thereof are also useful for treating or preventing diseases resulting from or associated with oxidative stress. Human lens thioltransferase and a DNA sequence encoding the same are also provided.
Factors Influencing Self-Rated Preparedness For Graduate School: A Survey Of Graduate Students, Matthew T. Huss, Brandy A. Randall, Marc Patry, Stephen F. Davis, David J. Hansen
Factors Influencing Self-Rated Preparedness For Graduate School: A Survey Of Graduate Students, Matthew T. Huss, Brandy A. Randall, Marc Patry, Stephen F. Davis, David J. Hansen
Department of Psychology: Faculty Publications
Numerous studies have found a host of factors that are likely to result in more successful applications to graduate schools. This study was a retrospective examination of the variables that distinguish graduate students who believed they were better prepared for graduate school. We examined several of these factors, including variables associated with undergraduate education and the individual for their relation to self-rated preparedness for graduate school. Our findings highlighted quality faculty interactions and participation in research as important factors in graduate students’ post hoc ratings of their preparedness for graduate school. We also found that different types of institutions differed …
Generalizing The Dynamic Field Theory Of The A-Not-B Error Beyond Infancy: Three-Year-Olds’ Delay- And Experience-Dependent Location Memory Biases, Anne R. Schutte, John P. Spencer
Generalizing The Dynamic Field Theory Of The A-Not-B Error Beyond Infancy: Three-Year-Olds’ Delay- And Experience-Dependent Location Memory Biases, Anne R. Schutte, John P. Spencer
Department of Psychology: Faculty Publications
Thelen and colleagues recently proposed a dynamic field theory (DFT) to capture the general processes that give rise to infants’ performance in the Piagetian A-not-B task. According to this theory, the same general processes should operate in noncanonical A-not-B-type tasks with children older than 12 months. Three predictions of the DFT were tested by examining 3-year-olds’ location memory errors in a task with a homogeneous task space. Children pointed to remembered locations after delays of 0 s to 10 s. The spatial layout of the possible targets and the frequency with which children moved to each target was varied. As …
The Effects Of Defendant Remorse On Mock Juror Decisions In A Malpractice Case, Brian H. Bornstein, Lahna M. Rung M.A., Monica K. Miller
The Effects Of Defendant Remorse On Mock Juror Decisions In A Malpractice Case, Brian H. Bornstein, Lahna M. Rung M.A., Monica K. Miller
Department of Psychology: Faculty Publications
The purpose of this study was to observe the effects of defendant remorse on monetary damages awarded to a plaintiff in a malpractice case. In two experiments, the physician-defendant expressed remorse at the time of the incident and again at trial, expressed remorse at trial, explicitly demonstrated a lack of remorse at trial, or made no mention of remorse (or a lack thereof). Participants decided how much money to award to the plaintiff and evaluated both the plaintiff and the defendant on several dimensions. Participants awarded greater compensation when the physician expressed remorse at the time of the incident than …
The Development Of A Measure Of Prosocial Behaviors For Late Adolescents, Gustavo Carlo, Brandy A. Randall
The Development Of A Measure Of Prosocial Behaviors For Late Adolescents, Gustavo Carlo, Brandy A. Randall
Department of Psychology: Faculty Publications
The correlates and structure of prosocial behaviors in late adolescents were examined using a newly constructed, multidimensional measure. In Study 1, 249 college students (145 women; M age = 19.9 years) were administered the Prosocial Tendencies Measure (PTM) which assesses 6 types of prosocial behaviors: altruistic, compliant, emotional, dire, public, and anonymous. Measures of sympathy, perspective taking, personal distress, social desirability, global prosocial behaviors, social responsibility, ascription of responsibility, vocabulary skills, and prosocial moral reasoning were also completed. Test-retest reliability and further validity of the PTM were demonstrated in Study 2 with a sample of 40 college students (28 women; …
Pretrial Publicity And Civil Cases: A Two-Way Street?, Brian H. Bornstein, Brooke L. Whisenhunt, Robert J. Nemeth, Deborah L. Dunaway
Pretrial Publicity And Civil Cases: A Two-Way Street?, Brian H. Bornstein, Brooke L. Whisenhunt, Robert J. Nemeth, Deborah L. Dunaway
Department of Psychology: Faculty Publications
Published pretrial publicity (PTP) research has been conducted almost exclusively with criminal cases and has focused on PTP that is detrimental to the defense. The current research examined the effects of PTP in a civil case to determine if PTP can have a biasing effect against either the defendant or the plaintiff in civil litigation. In Experiment 1, participants exposed to PTP biased against the defendant were more likely to reach a liable verdict than participants who read a control article or PTP biased against the plaintiff. Experiment 2 demonstrated that a judicial admonition did not reduce the biasing effect …
Improvement In Quantity And Quality Of Prevention Measurement Of Toddler Injuries And Parental Interventions, Lizette Peterson, David Dilillo, Terri Lewis, Kenneth Sher
Improvement In Quantity And Quality Of Prevention Measurement Of Toddler Injuries And Parental Interventions, Lizette Peterson, David Dilillo, Terri Lewis, Kenneth Sher
Department of Psychology: Faculty Publications
Injury is the leading killer of children in the United States, yet little research has focused on this vital subject. One of the distinct barriers to injury prevention is the absence of effective assessment devices. Epidemiological aspects of injury have been assessed, but these provide little information at a level sufficient to allow conclusions about potential behavioral prevention methods. This paper describes an alternative, the Participant Event Monitoring (PEM) system. In this paper, the PEM system is used to examine a sample of 170 toddlers (ages 18 to 36 months), over a 6-month period, resulting in data on over 4,200 …
Osmosensitive Release Of Neurotransmitter Amino Acids: Relevance And Mechanisms, Herminia Pasantes-Morales, Rodrigo Franco, Lenin Ochoa, Benito Ordaz
Osmosensitive Release Of Neurotransmitter Amino Acids: Relevance And Mechanisms, Herminia Pasantes-Morales, Rodrigo Franco, Lenin Ochoa, Benito Ordaz
School of Veterinary and Biomedical Sciences: Faculty Publications
Hyposmolarity activates amino acid efflux as part of the corrective volume process in a variety of cells. This review discusses the mechanism of amino acid release in brain cells preparations. Results present evidence of substantial differences between the efflux of taurine and that of GABA and glu-tamate, which besides a possible role as osmolytes, have a main function as synaptic transmitters. The differences found concern the efflux time course, the sensitivity to Cl– channel blockers, the modulation by tyrosine kinases, the influence of PKC and the effect of cytoskeleton disruptive agents. While taurine efflux features fit well with the …
A Gene Capable Of Blocking Apoptosis Can Substitute For The Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene And Restore Wild-Type Reactivation Levels, Guey-Chuen Perng, Barak Maguen, Ling Jin, Kevin R. Mott, Nelson Osorio, Susan M. Slanina, Ada Yukht, Homayon Ghiasi, Anthony B. Nesburn, Melissa Inman, Gail A. Henderson, Clinton J. Jones, Steven L. Wechsler
A Gene Capable Of Blocking Apoptosis Can Substitute For The Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene And Restore Wild-Type Reactivation Levels, Guey-Chuen Perng, Barak Maguen, Ling Jin, Kevin R. Mott, Nelson Osorio, Susan M. Slanina, Ada Yukht, Homayon Ghiasi, Anthony B. Nesburn, Melissa Inman, Gail A. Henderson, Clinton J. Jones, Steven L. Wechsler
School of Veterinary and Biomedical Sciences: Faculty Publications
After ocular herpes simplex virus type 1 (HSV-1) infection, the virus travels up axons and establishes a lifelong latent infection in neurons of the trigeminal ganglia. LAT (latency-associated transcript), the only known viral gene abundantly transcribed during HSV-1 neuronal latency, is required for high levels of reactivation. The LAT function responsible for this reactivation phenotype is not known. Recently, we showed that LAT can block programmed cell death (apoptosis) in neurons of the trigeminal ganglion in vivo and in tissue culture cells in vitro (G.-C. Perng et al., Science 287:1500–1503, 2000; M. Inman et al., J. Virol. 75:3636–3646, 2001). Consequently, …
Child Sexual Abuse, Eugenia Hsu, Georganna Sedlar, Mary Fran Flood, David J. Hansen
Child Sexual Abuse, Eugenia Hsu, Georganna Sedlar, Mary Fran Flood, David J. Hansen
Department of Psychology: Faculty Publications
This chapter describes the case of two adolescent girls who were living in foster care with their maternal aunt and her family, the Kraller family. The girls and their aunt and uncle participated in Project SAFE, a university-based program for sexually abused children and their nonoffending caregivers, which is described in detail in the Course of Treatment section. The Kraller family was referred to Project SAFE by the local Child Advocacy Center. Miriam Kraller contacted the Child Advocacy Center when she learned that her two nieces (her younger sister’s daughters), Gina (age 14) and Suzy (age 13), had been sexually …
Construction And Characterization Of A Chimeric Virus (Biv/Hiv-1) Carrying The Bovine Immunodeficiency Virus Gag-Pol Gene: Research Letters, Guomin Chen, Shuhui Wang, Kun Xiong, Jinzhong Wang, Tao Ye, Wenping Dong, Qi Wang, Qimin Chen, Yunqi Geng, Charles Wood, Yi Zeng
Construction And Characterization Of A Chimeric Virus (Biv/Hiv-1) Carrying The Bovine Immunodeficiency Virus Gag-Pol Gene: Research Letters, Guomin Chen, Shuhui Wang, Kun Xiong, Jinzhong Wang, Tao Ye, Wenping Dong, Qi Wang, Qimin Chen, Yunqi Geng, Charles Wood, Yi Zeng
Nebraska Center for Virology: Faculty Publications
HIV-1HXB2 5′LTR region, most of BIVR29 gag-pol segment and HIV-1HXB2 pol IN-3′LTR region were respectively amplified. A chimeric clone, designated as pHBIV3753, was constructed by cloning three fragments sequentially into pUC18. MT4 cells were transfected with pHBIV3753. The replication and expressions of the chimeric virus (HBIV3753) were monitored by RT activity and IFA. The results firstly demonstrated that it is possible to generate a new type of the BIV/HIV-1 chimeric virus containing BIV gag-pol gene.
Using Controversial Mock Trials In “Psychology And Law” Courses: Suggestions From Participants, James L. Werth, James Harvey, Rebecca Mcnamara, Andrea Svoboda, Raina Gulbrandson, Jennifer Hendren, Tiffany Greedy, Christie Leybold
Using Controversial Mock Trials In “Psychology And Law” Courses: Suggestions From Participants, James L. Werth, James Harvey, Rebecca Mcnamara, Andrea Svoboda, Raina Gulbrandson, Jennifer Hendren, Tiffany Greedy, Christie Leybold
Department of Psychology: Faculty Publications
We discuss the use of a mock trial of the controversial Jack Kevorkian euthanasia case in an undergraduate psychology and law course. We provide an overview of the project, student feedback, and recommendations for improving the exercise. Based on feedback from students, we conclude that constructing a trial around a controversial topic with psychosocial issues as the foundation of a course can increase the utility of a mock trial and make the course a better learning experience.
Predicting The Spatial Dynamics Of Rabies Epidemics On Heterogeneous Landscapes, David L. Smith, Brendan Lucey, Lance A. Waller, James E. Childs, Leslie A. Real
Predicting The Spatial Dynamics Of Rabies Epidemics On Heterogeneous Landscapes, David L. Smith, Brendan Lucey, Lance A. Waller, James E. Childs, Leslie A. Real
Zoonotics and Wildlife Disease: Publications
Often as an epidemic spreads, the leading front is irregular, reflecting spatial variation in local transmission rates. We developed a methodology for quantifying spatial variation in rates of disease spread across heterogeneous landscapes. Based on data for epidemic raccoon rabies in Connecticut, we developed a stochastic spatial model of rabies spread through the state’s 169 townships. We quantified spatial variation in transmission rates associated with human demography and key habitat features. We found that large rivers act as semipermeable barriers, leading to a 7-fold reduction in the local rates of propagation. By combining the spatial distribution of major rivers with …
The Federal Role In Regulating Alternative Livestock Operations, Jose R. Diez, Mike Gilsdorf, Robert Werge
The Federal Role In Regulating Alternative Livestock Operations, Jose R. Diez, Mike Gilsdorf, Robert Werge
Zoonotics and Wildlife Disease: Publications
This paper discusses one aspect of federal regulation for alternative livestock, namely that concerned with the health status of animal agriculture. Federal responsibility for animal health programs rests with Veterinary Services (VS), a unit of the Animal and Plant Health Inspection Service (APHIS), an agency of the United States Department of Agriculture (USDA). The objective of this paper is to briefly describe three aspects ofVS' policy that have a potential to impact alternative livestock as well as free ranging wildlife. These are (1) using cooperative state-federal programs to eliminate diseases in alternative livestock, (2) collaborating on health issues with a …
Preclinical Diagnosis Of Chronic Wasting Disease In Captive Mule Deer (Odocoileus Hemionus) And White-Tailed Deer (Odocoileus Virginianus) Using Tonsillar Biopsy, Margaret A. Wild, Terry R. Spraker, Christina J. Sigurdson, Katherine I. O'Rourke, Michael W. Miller
Preclinical Diagnosis Of Chronic Wasting Disease In Captive Mule Deer (Odocoileus Hemionus) And White-Tailed Deer (Odocoileus Virginianus) Using Tonsillar Biopsy, Margaret A. Wild, Terry R. Spraker, Christina J. Sigurdson, Katherine I. O'Rourke, Michael W. Miller
Zoonotics and Wildlife Disease: Publications
The usefulness of tonsillar biopsy on live deer for preclinical diagnosis of the transmissible spongiform encephalopathy chronic wasting disease (CWD) was evaluated. Disease was tracked in a CWD-endemic herd using serial tonsillar biopsies collected at 6 to 9 month intervals from 34 captive mule deer (Odocoileus hemionus) and five white-tailed deer (O. virginianus). Tonsillar biopsies were examined for accumulation of PrPCWD, the protein marker for infection, using immunohistochemical (IHC) staining. 26/34 (76%) mule deer and 4/5 (80%) white-tailed deer had PrPCWD accumulation in tonsillar biopsies; CWD was subsequently confirmed by post-mortem examination in …
Validation Of Monoclonal Antibody F99/97.6.1 For Immunohistochemical Staining Of Brain And Tonsil In Mule Deer (Odocoileus Hemionus) With Chronic Wasting Disease, T. R. Spraker, Katherine I. O'Rourke, A. Balachandran, R. R. Zink, B. A. Cummings, M. W. Miller, B. E. Powers
Validation Of Monoclonal Antibody F99/97.6.1 For Immunohistochemical Staining Of Brain And Tonsil In Mule Deer (Odocoileus Hemionus) With Chronic Wasting Disease, T. R. Spraker, Katherine I. O'Rourke, A. Balachandran, R. R. Zink, B. A. Cummings, M. W. Miller, B. E. Powers
Zoonotics and Wildlife Disease: Publications
A new monoclonal antibody (MAb), F99/97.6.1, that has been used to demonstrate scrapieassociated prion protein PrPSc in brain and lymphoid tissues of domestic sheep with scrapie was used in an immunohistochemistry assay for diagnosis of chronic wasting disease (CWD) in mule deer (Odocoileus hemionus). The MAb F99/97.6.1 immunohistochemistry assay was evaluated in brain and tonsil tissue from 100 mule deer that had spongiform encephalopathy compatible with CWD and from 1,050 mule deer outside the CWD-endemic area. This MAb demonstrated abnormal protease-resistant prion protein (PrPres) in brains of all of the 100 mule deer and in …
Pregnancy Status And Fetal Prion Genetics Determine PrpSc Accumulation In Placentomes Of Scrapieinfected Sheep, Wenbin Tuo, Katherine I. O'Rourke, Dongyue Zhuang, William P. Cheevers, Terry R. Spraker, Donald P. Knowles
Pregnancy Status And Fetal Prion Genetics Determine PrpSc Accumulation In Placentomes Of Scrapieinfected Sheep, Wenbin Tuo, Katherine I. O'Rourke, Dongyue Zhuang, William P. Cheevers, Terry R. Spraker, Donald P. Knowles
Zoonotics and Wildlife Disease: Publications
Ovine scrapie is a fatal neurodegenerative disorder that may be transmitted through exposure to infected uterine and placental tissues. Susceptibility to scrapie is primarily controlled by polymorphisms in the prion protein (PrP) gene. Scrapie in the U.S. Suffolk breed and in many breeds in Europe occurs in sheep homozygous for glutamine (171QQ), but rarely in sheep heterozygous for glutamine and arginine (171QR) or homozygous for arginine (171RR) at codon 171 of the PrP gene. This study demonstrated that accumulation of PrPSc in uterine-placental epithelial cells in the placentome was determined by fetal PrP genotype and the pregnancy status of …