Medicine and Health Sciences Commons^™

Prevalence Of Geriatric Syndromes In Elderly Undergoing Chemotherapy, Aulia Rizka, Helda Helda, Findy Prasetyawaty, Arcita Hanjani

Jurnal Penyakit Dalam Indonesia

Introduction. Geriatric syndromes is associated with poor survival, poor quality of life and increased chemotoxicity risk in elderly receiving chemotherapy. Geriatric syndromes is currently not routinely evaluated in pre-chemotherapy clinical setting. This study aimed to identify the prevalence of some geriatric syndromes in elderly patients undergoing chemotherapy.Methods. This study is part of primary study investigating geriatric syndromes in elderly with cancer. A descriptive cross sectional study during March 2020 – March 2021 was conducted to elderly patients before chemotherapy administration in Cipto Mangunkusumo Hospital, a national referral hospital in Jakarta. Patients were recruited consecutively. Patients underwent Comprehensive Geriatric Assesment (CGA), …

Outcome Result Of Acute Myeloid Leukemia Undergoing Treatment In Semi-Isolation Chemotherapy Ward, Cosphiadi Irawan, Ricci Steven, Ralph Girson Gunarsa, Jeffry Bela Tenggara

Jurnal Penyakit Dalam Indonesia

Introduction. Standard positive pressure isolation room is not yet widely available in Indonesia. In several private hospitals, current best practice is admitting patients to semi-isolation room with additional protective measures. Despite the limitation, this practice is considered safe and might benefit Acute Myeloid Leukemia (AML) patients. This study aimed to analyze the leukemic profile and survival in AML patients admitted to semi-isolation room. Methods. A retrospective cohort study was conducted using secondary data from medical record of AML patients diagnosed in Mochtar Riady Comprehensive Cancer Center between 2018 – 2020. Patients were divided into semi-isolation room group and not admitted …

Threats Of Covid-19 Reinfection: A Review Of The Evidence From The Literature, Muhammad Luthfi Adnan, Ana Fauziyati

Jurnal Penyakit Dalam Indonesia

Case of COVID-19 reinfection are related to immune factors in patients who have recovered by the natural course of the infecting pathogen. However, the chance of COVID-19 reinfection are still not well established. This review aimed to discuss about reinfection-related studies, including causes and clinical manifestations, and reinfection management. Reinfection happens when a patient is infected by the SARS-CoV-2 virus, which has a different genome from previous infection. Although the comparison of clinical manifestation between reinfection and the previous infection is not clear, it is believed that vulnerable populations may have worse outcomes. Vaccination is the main option to reduce …

Modulation Of The Nf-Κb Activation Pathway By Phycocyanobilin From Spirulina Platensis: An In Silico Study, Febriana Catur Iswanti, Hastuti Handayani S Purba, Ani Retno Prijanti, Fadilah Fadilah, Linda Herlina, Reni Paramita

Makara Journal of Science

Several studies have predicted the molecular interactions of the active ingredient of Spirulina platensis as an anti-inflammatory compound. However, these interaction studies did not review the modulation of the NF-κB activation pathway, which involves various factors. This study demonstrated the potential of the bioactive compounds of S. platensis for modulating immune function by reducing inflammation through the inhibition of the NF-κB activation pathway. Phycocyanobilin was predicted to have good potential for molecular docking with multisubunit IκB kinase (IKK)1/IKKA, IKK2/IKKB, NF-κB-inducing kinase, and the IκBα/NF-κB complex. Furthermore, β-carotene exhibited good potential for interactions with NF-κB essential modulator/IKK and the NF-κB complex, …

Synthesis Of Alginate/Hydroxyapatite Beads For Acetaminophen Delivery, Anesylvia Angan, Nonni Soraya Sambudi

Makara Journal of Science

Conventional drug delivery systems usually involve the intake of multiple drugs, which could amplify the risk of overdosing. Acetaminophen is a widely used pain relief substance that is prone to accidental overdosing. Hence, a controlled drug delivery system is needed to ensure its efficacy. A nanocomposite hydroxyapatite/alginate system that was used as a drug carrier for acetaminophen was synthesized through the sol-gel method, and the mechanism underlying its controlled drug delivery was investigated. Spherical nanocomposite bead samples were synthesized by incorporating 5 wt%, 10 wt%, and 15 wt% hydroxyapatite into mixtures containing alginate. The mixtures were then dropped into calcium …

Development And Optimization Of An Immunoassay For The Detection Of Antibodies Against Sars-Cov-2 With In-House Recombinant Rbd Protein, Safira Pinaka Pramestika Ratu, Silmi Mariya, Rachmitasari Noviana, Uus Saepuloh, Huda Salahudin Darusman

Makara Journal of Science

COVID-19 caused by SARS-CoV-2 poses a major threat to the global community, particularly in Indonesia. Countermeasures to prevent the spread of this disease have also been implemented, including the implementation of a vaccination program. An immunoassay technique that can be used to analyze antibodies that might develop following vaccination is the indirect enzyme-linked immunosorbent assay (ELISA). We produced the recombinant spike protein used in this study. The optimization comprised adjusted concentrations of spike recombinant protein (5 and 10 ng/mL), blocking agent (2.5% and 5%), and conjugate (1:1000 and 1:5000). The optimal conditions in this study included a spiked concentration of …

Service Of People With Psychiatric Problems (Odmk) At The Pasar Baru Health Center And Pabuaran Tumpeng Health Center In Tangerang City In 2022: A Comparative Study, Mentari Kirana Firdaus, Masyitoh Basabih

Journal of Indonesian Health Policy and Administration

Mental health is one of the global health issues with cases that continue to increase every year. In 2019, psychiatric problems were the second leading cause of disability worldwide with a total of 970 million cases. This research is a comparative study that aims to determine the difference between ODMK services at Pasar Baru Health Center and Pabuaran Tumpeng Health Center. This research uses a qualitative approach with a case study method, data collection is done through in-depth interviews and document review. The variables analyzed include input, process, and output. The results of the study found that in the input …

Analysis Of Factors Related To Intention-To-Use Telemedicine Services (Teleconsultation) In Jabodetabek Residents During The Covid-19 Pandemic In 2021, Isna Mutiara Salsabila, Kurnia Sari

Journal of Indonesian Health Policy and Administration

The emergence of COVID-19 pandemic has made it difficult for people to access health services. According to JKN statistics, FKTP visits was decreased from 337.69 million (2019) to 193.03 (2021). Teleconsultation, a type of telemedicine, could be the right solution so that people can still access the health services they need and protect themselves from the spread of COVID-19. There was an increase in the use of several teleconsultation applications in Indonesia during pandemic, from 4 million to more than 15 million people. However, this rate is only 7.63% of the internet users and 5.6% of the total population of …

Analysis Of Prolanis Policy Implementation During The Covid-19 Pandemic In 2021, D.Fitria Sari Firdaus, Mardiati Nadjib

Journal of Indonesian Health Policy and Administration

Data from Basic Health Research (Riskesdas) in 2018 shows that Diabetes and Hypertension dominate chronic diseases. The Director of BPJS Kesehatan has issued Circular No. 14 of 2020 concerning health services for national health insurance participants during the COVID-19 prevention period, especially Prolanis. The policy contains an appeal to postpone the provision of services in the form of mass gathering activities such as Prolanis Gymnastics, Club Education, and and other activities. Hence, this research is needed to describe the implementation of Prolanis policies during the COVID-19 Pandemic. The study used a descriptive research design with qualitative methods and George C. …

Description Study Of Pandeglang Community Knowledge On Natural Disasters And Government Policies Related To Natural Disaster Preparedness In 2022, Novi Anggraini Ginting, Wiku Bakti Bawono Adisasmito

Journal of Indonesian Health Policy and Administration

Pandeglang Regency, which is a disaster-prone area, requires people who have sufficient knowledge to create community preparedness in dealing with disasters and can assist in the disaster mitigation process. This study aims to find out how the community's knowledge and community preparedness related to natural disasters and what efforts have been made by the government to improve the readiness of the people of Pandeglang Regency. This research method is descriptive and quantitative with 451 respondents. The results of the study showed that the people of Pandeglang Regency still did not know correctly the different types of threats or types of …

Analysis Of The Need For Legal Protection For Doctors In Teleconsultation Services Towards The Covid-19 Endemic In Indonesia, Mila Fitriana, Anhari Achadi

Journal of Indonesian Health Policy and Administration

Teleconsultation is a form of telemedicine that has developed rapidly during the COVID-19 pandemic. Clinical teleconsultation provides remote clinical consultation services to assist in establishing a diagnosis, and/or providing treatment considerations/advice. There are several issues in telemedicine, including ethical and legal issues. This study aims to find ethical and legal issues related to teleconsultation services after the COVID-19 pandemic. This research uses normative legal research methods. The laws and regulations that are reviewed by the researcher are those that are still valid in the Republic of Indonesia until June 2022. Researchers compare teleconsultation regulations and laws that were in effect …

Association Of Methylenetetrahydrofolate Reductase Rs1801133 Genetic Variants With Type 2 Diabetes Mellitus And Diabetic Nephropathy, Aysegul Bayramoglu, Gokhan Bayramoglu, Halil Ibrahım Guler, Nezaket Coban, Mustafa Çagatay Korkmaz

Makara Journal of Health Research

Background: Type 2 diabetes mellitus (T2DM) is a complex metabolic disease with a genetic predisposition. Methylenetetrahydrofolatereductase (MTHFR) gene is one of the candidate genes associated with T2DM and diabetic nephropathy (DN). This research was carried out to determine the frequency of the C677T polymorphism (rs1801133) of the MTHFR gene and examine the role of rs1801133 polymorphism in T2DM and DN development.

Methods: DNA was obtained from peripheral blood samples (273 samples) using a DNA isolation kit. MTHFR rs1801133 polymorphism was determined using polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP), and electrophoresis. PCR products were cut by …

Factors Influencing The Choice Of Toothpaste And Investigation Of Those Most Commercialized By Students In Settat, Morocco, Abdellatif Rahim, Wissal El Karfi, Lalla Asmaa Katir Masnaoui, Bouchra El Amiri, Abdel Khalid Essamadi

Makara Journal of Health Research

Background: This study aimed to determine the factors influencing the choice of toothpaste by students in Settat (Morocco) and investigate the characteristics of those most commercialized in this region.

Methods: A close-ended questionnaire was developed and filled out. This was a cross-sectional study of 429 students who agreed to participate. Based on questionnaire data, the 15 most commercialized toothpaste by respondents were purchased, and their packaging was investigated.

Results: After analysis using Excel 2019, the results revealed that the major factors influencing the choice of toothpaste are brand 55%, family choice 48%, and media advertisements 40%. Moreover, …

Patient Experience Of Inpatient Care And Services Received At A Teaching Hospital In Malaysia: A Cross-Sectional Study, Wan Nor Fatihah Wan Nawawi, Vimala Ramoo, Mei Chan Chong, Nor Zehan Ahmad

Makara Journal of Health Research

Background: Patients’ experience reflects the quality of healthcare services from the end user’s perspective and therefore is an essential indicator of healthcare quality. This study aimed to measure patient experience of inpatient care and services received at a teaching hospital.

Methods: A total of 321 patients were enrolled in this quantitative, cross-sectional study during their discharge. Data were collected from May to September 2018 through a validated self-administered questionnaire adapted from the Hospital Consumer Assessment of Healthcare Providers and Systems survey. Analysis of patient experience and overall hospital quality rating was conducted using SPSS version 25.

Results: …

Spatial Analysis For Enhancing The Use Of Health Data Availability From Different Sources To Help The Decision-Making Process, Tris Eryando

Kesmas

Spatial analysis in public health has become a common method used by researchers to understand the distribution of public health aspects related to the surrounding environment. It can also be used to analyze individual information in the form of a dot and the location or line of aggregated information in a specific area of study. Another benefit is the possibility of using different data sources to be analyzed in one statistical model analysis, as long as the identification area is sufficiently clear as a key variable. Spatial analysis can show an object's distribution on a locational map and explain the …

Sars-Cov-2 Antibody Seroprevalence In Jakarta, Indonesia, Iwan Ariawan, Hafizah Jusril, Muhammad N Farid, Pandu Riono, Wiji Wahyuningsih, Widyastuti Widyastuti, Dwi Oktavia T L Handayani, Endang Sri Wahyuningsih, Rebekka Daulay, Retno Henderiawati, Safarina G. Malik, Rintis Noviyanti, Leily Trianty, Nadia Fadila, Khin Saw Aye Myint, Frilasita A. Yudhaputri, Neeraja Venkateswaran, Kodumudi Venkateswaran, Venkatachalam Udhayakumar, William A. Hawley, Juliette Morgan, Paul M. Pronyk

Kesmas

The SARS-CoV-2 transmission dynamics in low- and middle-income countries remain poorly understood. This study aimed to estimate the SARS-CoV-2 antibodies seroprevalence in Jakarta, Indonesia, and to increase knowledge of SARS-CoV-2 transmission in urban settings. A population-based serosurvey among individuals aged one year or older was conducted in Jakarta. Employing a multistage sampling design, samples were stratified by district, slum, and non-slum residency, sex, and age group. Blood samples were tested for IgG against three different SARS-CoV-2 antigens. Seroprevalence was estimated after applying sample weights and adjusting for cluster characteristics. In March 2021, this study collected 4,919 respondents. The weighted estimate …

A Stunting Prevention Risk Factors Pathway Model For Indonesian Districts/Cities With A Stunting Prevalence Of ≥30%, Nina Fentiana, Endang L. Achadi, Besral Besral, Abram Kamiza, Trini Sudiarti

Kesmas

The prevalence of stunting in Indonesian children aged 0-23 months is a public health problem caused by direct and indirect factors. This study aimed to discover the path of the relationship between various risk factors and the stunting prevalence of ≥30% in 165 districts/cities in Indonesia. Data were obtained from the 2018 National Basic Health Research, National Socioeconomic Survey, and the Statistics Indonesia with a cross-sectional approach. The secondary data on stunting and risk factors were aggregated at the district/city level from individual data; children aged 0-23 months. The path analysis used to determine a stunting prevention model showed that …

Determinants Of Type 2 Diabetes Mellitus Among Passive Smokers, Adinda Rahma Triyaniarta, Santi Martini, Kurnia Dwi Artanti, Sri Widati, Rizma Dwi Nastiti

Kesmas

Type 2 diabetes mellitus (T2DM) leads to complications of other diseases. The modifiable risk factors for T2DM are overweight, physical activity, hypertension, unhealthy diet, and smoking. This study aimed to analyze determinants of T2DM incidence in passive smokers among various factors. This study was conducted at Hospital X in Surabaya City, East Java Province, Indonesia, from September 2019 to April 2020. The variables were univariate, bivariate, and multivariate. Case samples were T2DM patients and passive smokers, while control samples were non-T2DM patients and passive smokers, with 52 respondents per group, of 104 total respondents. Variables statistically significant related to the …

The Effect Of Health Promotion Program On Perceived Self-Efficacy And Self-Care Practices Among Elderly With Multimorbidity In Chiang Mai, Thailand, Jukkrit Wungrath, Nuttida Khumai, Phinphot Phrommasen

Kesmas

Multimorbidity in the elderly is a major public health issue with serious consequences. This study investigated the effects of health promotion programs on perceived self-efficacy and self-care practices among the elderly with multimorbidity using a quasi-experimental study design from February to July 2021. The study samples were the elderly from Doi Saket District, Chiang Mai Province, Thailand, selected by a multistage random sampling technique. The experimental and control groups each comprised 40 elderlies with multimorbidity. All elderly participants took part in a 12-week health promotion program. The perceived self-efficacy and self-care practices of the study samples were assessed using interviews, …

Predictors Of Anxiety Toward Covid-19 Delta Variant: A Cross- Sectional Study Among Healthcare Providers In Java And Bali, Indonesia, I Ketut Swarjana, I Gede Putu Darma Suyasa, I Kadek Nuryanto

Kesmas

Health facilities are experiencing overcapacity, oxygen scarcity, and a limited number of healthcare providers due to the coronavirus disease 2019 (COVID-19), thus impacted on anxiety. This study aimed to determine predictors of anxiety among healthcare providers toward the Delta variant of COVID-19 in Indonesia. A cross-sectional study was conducted with 371 healthcare providers in Java and Bali Islands, and the snowball sampling technique was used. Data were collected using a questionnaire and distributed through social media (WhatsApp), then analyzed using univariate analysis, bivariate analysis (Chi-square test), and multivariate analysis (multiple logistic regression). The results showed that 81 (21.8%) respondents experienced …

Perspectives On Reproductive Health Education Among Javanese Parents, Bagoes Widjanarko, Ratih Indraswari, Aditya Kusumawati, Novia Handayani

Kesmas

This study aimed to investigate the perspectives of reproductive health education among Javanese parents of children aged 9-11 years. This cross-sectional study was conducted with 12,306 parents in Semarang City, Central Java Province, Indonesia, using a purposive sampling technique. Some parents agreed that reproductive health education at home was unnecessary (29.5%), taboo (45%), difficult (73.1%), and awkward (41.5%). Most parents (72.7%) were not transparent in providing reproductive health information to their children by using other terms to name the genitals, considering the politeness aspect. Good practices of providing reproductive health information are slightly more common in mothers (54.2%), unemployed parents …

Spatial Analysis Of Seven Islands In Indonesia To Determine Stunting Hotspots, Tiopan Sipahutar, Tris Eryando, Meiwita Budiharsana

Kesmas

Indonesia is a vast country struggling to reduce its stunting prevalence. Hence, identifying priority areas is urgent. In determining areas to prioritize, one needs to consider geographical issues, particularly correlations among areas. This study aimed to discover whether stunting prevalence in Indonesia occurs randomly or in clusters; and, if it occurs in clusters, which areas are the hotspots. This ecological study used aggregate data from the 2018 National Basic Health Research and Poverty Data and Information Report from the Statistics Indonesia. This study analyzed 514 districts/cities across 34 provinces on seven main islands in Indonesia. The method used was the …

Model Autonomy Of Self-Finance Management For Primary Health Care To Enhance Workers’ Satisfaction, Ahmad Jet Alamin, Ossama Issac, Lina Teo, Atikah Adyas

Kesmas

This study aimed to find an appropriate model of autonomous self-finance management in primary health care (PHC) to enhance workers' satisfaction. This was a cross-sectional study in which data were collected through self-administered questionnaires from 204 workers in ten Regional Public Service Agency for Primary Health Care (RPSAPHC)/Badan Layanan Umum Daerah Pusat Kesehatan Masyarakat (BLUD Puskesmas) in Tangerang District, Banten Province, Indonesia using the partial least squares and structural equation model (PLS-SEM). A total of 73 indicators were used to examine the PHC transformation process to enhance workers' satisfaction. The indicators were grouped into three variables depending on workers' satisfaction: …

Cross-Sectional Study On Overweight And Obesity Associated With Fast-Food Consumption In Bangladesh, Farhana Sultana, Shafayet Ahmed Siddiqui, Md. Ashraful Islam, Mohammad Hamid Al Muktadir, Md. Shalahuddin Millat, Muhammed Mohibul Islam, Abu Montakim Tareq, Nahida Afroz, Mahabuba Rahman, Mohammad Nurul Amin, Talha Bin Emran

Makara Journal of Health Research

Background: This study aimed to investigate the risk factors and status of fast-food consumption among students in Bangladesh.

Methods: This cross-sectional study was conducted from March to November 2020. A total of 654 samples were collected from several schools, colleges, and universities during this study period.

Results: About 60.1% and 39.9% of the students were male and female, respectively. Of the students, 53.1% considered fast food as unhealthy (p < 0.001), but only 47.7% were leading a sedentary lifestyle. A significant outcome of overweight and pre-obesity was observed for student institutions, consumption frequency, daily fast-food consumption, and sedentary lifestyle (p < 0.001). In addition, positive association was observed for fast-food consumption more than three times and less than three times per week (OR and 95% CI: 11.13 [7.52–16.47], p < 0.001), higher social class and lower class (OR and 95% CI: 2.18 [1.31–3.62], p = 0.003), fast food preference and other foods (OR and 95% CI: 1.55 [1.11–2.15], p = 0.009), and sedentary and heavily active lifestyle (OR …

Prioritizing Training Needs For Nurses In The Government Hospitals Of The Ha’Il Region, Saudi Arabia: Future Directions For Educational Developers, Eddieson Pasay-An, Hatem Homoud Alsrour

Makara Journal of Health Research

Background: The assessment of training needs can help establish the current performance or knowledge levels related to certain essential nursing activities. The purpose of this study is to determine the training needs of the staff nurses of the government hospitals in Ha’il Region, Saudi Arabia.

Methods: This study employed a cross-sectional–correlational approach with 230 staff nurses of the government hospitals in the City of Ha’il. Random sampling was used to ensure the representativeness of the sample.

Results: The nurses perceived training activities as very important (6.22 ± 1.09) in their work but performed the necessary activities only …

Determining Individuals’ Attitudes Toward Cancer Screening And Their Influential Factors, Emre Erkal

Makara Journal of Health Research

Background: Cancer screenings are of great importance for the early detection of cancer. The goal of this study is to determine the attitudes of individuals toward cancer screening and the factors affecting these attitudes.

Methods: This descriptive, cross-sectional study comprised 1059 participants who were living in Turkey. The participants were recruited through the snowball sampling method between December 6 and 24, 2021. The Individual Self-Assessment Form and Attitude Scale for Cancer Screening were used to collect data. The data were analyzed by using independent samples t-test, one-way ANOVA, and Pearson’s correlation analysis.

Results: The mean score of …

Body Image Perception And Its Association With Food Intake Among Undergraduate Students In Kuala Lumpur, Malaysia, Christie Loke Sin Mun, Roslee Rajikan, Hanis Mastura Yahya

Makara Journal of Health Research

Background: Body image dissatisfaction may lead to the practice of imbalanced diet to achieve the desired body weight. This study aimed to determine the association between body image perception and food intake among undergraduate students.

Methods: This cross-sectional study was conducted on the data of 155 students from three faculties located at National University of Malaysia, Kuala Lumpur. Assessments included demographic data, body mass index, Contour Drawing Rating Scale, and 3-day food records.

Results: The majority of the subjects were categorized as normal weight (64.5%), and the remaining were classified as underweight (26.5%), overweight (7.7%), and obese …

Association Between Social Support And Three Types Of Loneliness Among Rural Older Adults In Johor, Malaysia, Siti Zuhaida Hussein, Norazilah Khalip, Selamah Ismail, Mohammad Fariq Hatta

Makara Journal of Health Research

Background: Social support plays a vital role in ensuring the well-being and quality of life of older people.

Methods: This cross-sectional survey was conducted among 380 older adults residing in a rural district in Johor, Malaysia. A proportional stratified random sampling was used to examine the relationship between social support and three types of loneliness. The data were collected using the Short-Form Social and Emotional Loneliness Scale for Adults and Lubben Social Network Scale–6, with p < 0.05 considered as statistically significant. Data analysis was performed using the Statistical Package for the Social Sciences Statistics 26.0 for Windows.

Results: More than half of the older adults in this rural area received social support from their family and friends. The …

Use Of Audio Devices To Increase Preventive Health Behavior During Dental Visits, Normaliza Ab Malik, Azlan Jaafar, Aws Hashim Ali, Rusyda Helma Mohd, Nor Ba'yah Abdul Kadir

Makara Journal of Health Research

Background: Compliance with preventive health behavior is crucial during dental visits. This study investigated using an audio device to increase dental patients’ preventive health behavior.

Methods: A randomized control study was conducted in private dental practices. The test group listened to an audio device containing public health messages related to COVID-19 and preventive health behavior. The control group listened to relaxing instrumental music with no public health messages.

Results: A total of 65 participants (age 18–77 years) were allocated to each group. About 63% of the participants in the test group performed preventive health behaviors compared to …

Comparisons Of Microleakage And Scanning Electron Microscope Sem Analyzes Of The Use Of Different Pulp Coverage Materials, Yasemin Yavuz, Sedef Kotanli, Mehmet Sinan Doğan, Kemal Doğan

Makara Journal of Health Research

Background: The aim of this study was to compare three different pulp coverage materials with calcium silicate content considering microleakage in the cavity floor and evaluate the gaps with a stereomicroscope and scanning electron microscope SEM.

Methods: A total of 40 human molar teeth were used in this study, and class V (4 mm mesio-distal × 3 mm gingivo-occlusal × 3 mm depth) cavities were prepared. The samples were divided into four groups (N = 10), including NeoPutty(Nusmile), Biodentin (Septodont), and TheraCal PT (Bisco). All groups were restored using Single Bond Universal adhesive and Filtek Z250 (3M ESPE). …