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Articles 8161 - 8190 of 14935

Full-Text Articles in Medicine and Health Sciences

Portable Privacy, Larken Mccarthy (Interior Design), Breah Banks (Landscape Architecture) Sep 2017

Portable Privacy, Larken Mccarthy (Interior Design), Breah Banks (Landscape Architecture)

Nexus Maximus

Creating a temporary home for displaced people in times of crisis by maximizing vertical space within an air pitch housing structure.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. That’s 34,000 people a day who leave everything behind in the hope of finding safety and a better tomorrow. The impact of war, political, racial and religious conflict, and …


Intgrt, John Cecil (Industrial Design), Veronica Reguero Cadilla (Industrial Design), Keaghan Caldwell (Sustainability Design), Emmalee Vansciver (Interior Design) Sep 2017

Intgrt, John Cecil (Industrial Design), Veronica Reguero Cadilla (Industrial Design), Keaghan Caldwell (Sustainability Design), Emmalee Vansciver (Interior Design)

Nexus Maximus

We are a non-profit organization with the goal to resettle refugees into a small-scale community with opportunities of education, employment, and housing. With the focus on cities between a 5,000 to 60,000 population, refugees have the chance to utilize their skill sets to improve and evolve a current community without being strongly labeled as a “refugee.”

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world …


Space Data Industries, Abram Gibson (Pre-Med), Bruno Jacobsen, Axel Juslin, Philip Smith (Biology) Sep 2017

Space Data Industries, Abram Gibson (Pre-Med), Bruno Jacobsen, Axel Juslin, Philip Smith (Biology)

Nexus Maximus

Winner of the most entrepreneurial award for its concept of helping government institutions predict, understand and prepare for refugee migration flows through data insights.

A poster that explains a hypothetical company that helps proactively assist governments and refugees during the migration process. The company is based off of data from the groundbreaking nano-satellites being produced at Aalto University.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around …


Amicus: Communication Across Languages, Brian Cipperly (Industrial Design), Rosario Herrera (Graphic Design), Mike Savarie (Sustainable Design) Sep 2017

Amicus: Communication Across Languages, Brian Cipperly (Industrial Design), Rosario Herrera (Graphic Design), Mike Savarie (Sustainable Design)

Nexus Maximus

MOST INNOVATIVE SOLUTION AWARD

Our project is designed to serve as a means for speakers of different languages to communicate using pictorial icons, particularly to serve basic needs such as food and water. At a refugee camp or other first point of contact, a volunteer or aid worker can be wearing a t-shirt, giving away blankets, or using flash cards with the symbols printed on them and the refugee can communicate their needs.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, …


The Children's Community Center, Noelle Howard (Economics), Silvia Martin Aldana (Graphic Design Certificate), Cristina Pareja (Disaster And Medicine And Management), Albaraa Jebreel (Disaster And Medicine And Management) Sep 2017

The Children's Community Center, Noelle Howard (Economics), Silvia Martin Aldana (Graphic Design Certificate), Cristina Pareja (Disaster And Medicine And Management), Albaraa Jebreel (Disaster And Medicine And Management)

Nexus Maximus

We are the Children’s Community Center, a NGO thats wants to provide an emergency response to the new surge of Rohingya refugee children. We want to relieve the daily mental traumas of the refugee camps through the collaborative interaction of the different children within the camps. This center will also give parents the space to focus on their own healing without the preoccupation of childcare.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the …


Combating The Problem Of Smuggling Via Legal Refugee Transport Agencies, Mitchell Maurer (Engineering), Ala Saleh, Alex Marino, Adam Hoover, Imani Pajibo, Gabriel De Toro Cruzat Sep 2017

Combating The Problem Of Smuggling Via Legal Refugee Transport Agencies, Mitchell Maurer (Engineering), Ala Saleh, Alex Marino, Adam Hoover, Imani Pajibo, Gabriel De Toro Cruzat

Nexus Maximus

Our final project is the idea of an organization that works to legally transport refugees into the EU where they can safely become members of the local economy. Legal and social loopholes prevent refugees from entering easily, while refugees are actually seen to aid in temporary working economies.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. That’s 34,000 …


Unite App: Connecting Refugees And Locals, Aubrey Coughlin (Interior Design), Anna Loimusalo (Information And Service Management), Anthony Difranco (Industrial Design), Bennett Purdy (Textile), Mismilad Alhashim (Pre-Med), Winston Folkes (Occupational Therapy) Sep 2017

Unite App: Connecting Refugees And Locals, Aubrey Coughlin (Interior Design), Anna Loimusalo (Information And Service Management), Anthony Difranco (Industrial Design), Bennett Purdy (Textile), Mismilad Alhashim (Pre-Med), Winston Folkes (Occupational Therapy)

Nexus Maximus

Unite is a social media platform which connects refugees with local organizations and anyone who wants to lend a hand, when they arrive in a new country. To make our concept more specific, we focused on the city of Berlin, the organizations which exist there and the people who are migrating there.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee …


Refugee.Jobs, Laura Dunne (Pa Studies), Jonathan Looi (Computer Science), Jose Tomas Marchant (Industrial Design), Devin Morrison (Industrial Design) Sep 2017

Refugee.Jobs, Laura Dunne (Pa Studies), Jonathan Looi (Computer Science), Jose Tomas Marchant (Industrial Design), Devin Morrison (Industrial Design)

Nexus Maximus

Refugee.jobs connects prospective refugee workers with both American employers and English language education resources. Employers who participate in Refugee.jobs are educated about the benefits of hiring refugees and are provided with answers to their concerns by Refugee.jobs liasons. Key players in the success of Refugee.jobs are local refugee resettlement agencies and cultural communities.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to …


Category 5, Michael A. Gregori (Landscape Architecture), Kelly Dutertre (Accounting), Catalina Arce Elton (Marketing), Griffin Voight (Landscape Architecture) Sep 2017

Category 5, Michael A. Gregori (Landscape Architecture), Kelly Dutertre (Accounting), Catalina Arce Elton (Marketing), Griffin Voight (Landscape Architecture)

Nexus Maximus

Follow Elizabeth and her family through this family oriented video series which highlights topics such as preparing for a hurricane, how to help those affected by a storm and raises awareness for mental health after a natural disaster.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. That’s 34,000 people a day who leave everything behind in the hope …


Hope Box, Ted Thresh (Industrial Design), Erica Lomando, Monica Tabet, Delara Kiani (Industrial Design), Iiro Nurmi Sep 2017

Hope Box, Ted Thresh (Industrial Design), Erica Lomando, Monica Tabet, Delara Kiani (Industrial Design), Iiro Nurmi

Nexus Maximus

The Hope Box is a purse sized container with the main purpose of giving people hope that not all is lost. This container locks and can hold your personal valuables safely from theft or water or abrasion damage.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. That’s 34,000 people a day who leave everything behind in the hope …


Refugee Connects, Chintha Snow Vongsakulvong (Interior Design), John Murphy, Maria Latorre, Alejandra Hernandez Sep 2017

Refugee Connects, Chintha Snow Vongsakulvong (Interior Design), John Murphy, Maria Latorre, Alejandra Hernandez

Nexus Maximus

Refuge Connects

An opportunity for Refugees Syrian refugees are in a vulnerable state while in their camps, mentally, physically, and economically. They miss their homes, jobs, and their old community. While waiting to hear about their asylum status, they want to have a sense of normality. Refugees have limited access to job opportunities, which delays productivity for families. When trying to strive for normality in their current state, having a steady source of income will stabilize their lives.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to …


Life, Kendall Hancock (Fashion Design), Damien Vela, Fancy Castillo, Monica Barrera (Interior Design), Terry Rim Sep 2017

Life, Kendall Hancock (Fashion Design), Damien Vela, Fancy Castillo, Monica Barrera (Interior Design), Terry Rim

Nexus Maximus

This project is about offering a solution to nationally displaced populations. Our group has created a system that will not only provide people with housing but a piece of mind.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. That’s 34,000 people a day who leave everything behind in the hope of finding safety and a better tomorrow. The …


Bookbox, Suraksha Chandrasekhar (Dmm), Anna Marinina (Computer Science), Gabrielle Schwartz (Mba, Marketing/Business Analytics), Erica Lomando (Interior Design), Sarah Von Lange (Health Sciences) Sep 2017

Bookbox, Suraksha Chandrasekhar (Dmm), Anna Marinina (Computer Science), Gabrielle Schwartz (Mba, Marketing/Business Analytics), Erica Lomando (Interior Design), Sarah Von Lange (Health Sciences)

Nexus Maximus

Bookbox is an app that unites the world through books. With a motto of "Donate a book, start a new chapter" Bookbox aims to facilitate the flow of donated books to refugees in Syrian refugee camps, with a goal of promoting education, self-learning and the will to build a future.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our time is how to help refugees and displaced populations, and how to prevent the causes in the first place. Every minute, 24 people around the world are forced to flee their homes. …


Mobile Health One Kiosk, Nathoue Noel (Public Administration), Giana Castelli (Interior Design), Nazanin Salehima (Interior Design), Queen Mgbechinyere (Nursing), Yasir Almukhifi (Disaster Management And Medicine), Salwa Rasheed (Textile Design) Sep 2017

Mobile Health One Kiosk, Nathoue Noel (Public Administration), Giana Castelli (Interior Design), Nazanin Salehima (Interior Design), Queen Mgbechinyere (Nursing), Yasir Almukhifi (Disaster Management And Medicine), Salwa Rasheed (Textile Design)

Nexus Maximus

The goal of this machine is to decrease the wait time to see a physician or doctor when a refugee goes to a clinic. The machine will perform the first tests that a nurse would have to do before the patient meet the doctor. The machine allows this process to be quicker by doing tests, set up appointments for refugees to see a doctor,give the estimated wait time at clinics and also to direct people to the right section of the clinic once they get there.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the …


Half Full: A Personal Water Collection System, Matthew Cuccurese (Industrial Design), Andres Valbuena, Pooja Joshi (Occupational Therapy), Sophia Warne Rowe (Interior Design), Samantha Ringer (Interior Design) Sep 2017

Half Full: A Personal Water Collection System, Matthew Cuccurese (Industrial Design), Andres Valbuena, Pooja Joshi (Occupational Therapy), Sophia Warne Rowe (Interior Design), Samantha Ringer (Interior Design)

Nexus Maximus

Our project focuses on the issue of water within refugee camps. We have proposed a system that can allow for individuals to be able to have their own source of drinking water with a device that can condensate water from the air, even in an aired region. This would allow them to use less water from the community's supply overall, and allow more water to be able to be rationed for uses like washing and cleaning than is currently rationed per person.

Nexus Maximus IV

The Challenge: Innovation for Refugees and Displaced Populations

One of the great challenges of our …


A Word From The Writing Center (September 2017), Jennifer Wilson, Ms, Els Sep 2017

A Word From The Writing Center (September 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

  • Writing Tip: Sentences that start with the word there
  • Communication Skills Workshop Series: Communicate Like a Pro: Think like a...


Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As A Graft Source For T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide., Asad Bashey, Mei-Jie Zhang, Shannon R Mccurdy, Andrew St Martin, Trevor Argall, Claudio Anasetti, Stefan O Ciurea, Omotayo Fasan, Sameh Gaballa, Md, Mehdi Hamadani, Pashna Munshi, Monzr M Al Malki, Ryotaro Nakamura, Paul V O'Donnell, Miguel-Angel Perales, Kavita Raj, Rizwan Romee, Scott Rowley, Vanderson Rocha, Rachel B Salit, Melhem Solh, Robert J Soiffer, Ephraim Joseph Fuchs, Mary Eapen Sep 2017

Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As A Graft Source For T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide., Asad Bashey, Mei-Jie Zhang, Shannon R Mccurdy, Andrew St Martin, Trevor Argall, Claudio Anasetti, Stefan O Ciurea, Omotayo Fasan, Sameh Gaballa, Md, Mehdi Hamadani, Pashna Munshi, Monzr M Al Malki, Ryotaro Nakamura, Paul V O'Donnell, Miguel-Angel Perales, Kavita Raj, Rizwan Romee, Scott Rowley, Vanderson Rocha, Rachel B Salit, Melhem Solh, Robert J Soiffer, Ephraim Joseph Fuchs, Mary Eapen

Department of Medicine Faculty Papers

Purpose T-cell-replete HLA-haploidentical donor hematopoietic transplantation using post-transplant cyclophosphamide was originally described using bone marrow (BM). With increasing use of mobilized peripheral blood (PB), we compared transplant outcomes after PB and BM transplants. Patients and Methods A total of 681 patients with hematologic malignancy who underwent transplantation in the United States between 2009 and 2014 received BM (n = 481) or PB (n = 190) grafts. Cox regression models were built to examine differences in transplant outcomes by graft type, adjusting for patient, disease, and transplant characteristics. Results Hematopoietic recovery was similar after transplantation of BM and PB (28-day neutrophil …


Finding The Right Fit To Improve Colorectal Cancer Screening, Joseph Spataro, Richard Denicola, Drew Kotler, Md, Albert Lee, Md Sep 2017

Finding The Right Fit To Improve Colorectal Cancer Screening, Joseph Spataro, Richard Denicola, Drew Kotler, Md, Albert Lee, Md

Department of Medicine Posters

Background

  • An estimated 28% of eligible US adults have never been screened for colorectal cancer (CRC) 2
  • Fecal Immunochemical Testing (FIT) offers an acceptable non-invasive screening option
  • An estimated 56% of patients at our internal medicine clinic have not had colorectal cancer screening and alternatives to colonoscopy were seldom promoted

Poster presented at: Pennsylvania Society of Gastroenterology (PSG) Annual Scientific Meeting 2017 at Nemacolin Woodlands Resort, Farmington, Pennsylvania, United States of America.


Acute And Late Toxicities Of Concurrent Chemoradiotherapy For Locally-Advanced Non-Small Cell Lung Cancer., Vivek Verma, Charles B 2nd Simone, Maria Werner-Wasik Sep 2017

Acute And Late Toxicities Of Concurrent Chemoradiotherapy For Locally-Advanced Non-Small Cell Lung Cancer., Vivek Verma, Charles B 2nd Simone, Maria Werner-Wasik

Department of Radiation Oncology Faculty Papers

For patients with unresectable locally-advanced non-small cell lung cancer (LA-NSCLC), concurrent chemoradiotherapy improves overall survival as compared to sequential chemotherapy and radiation therapy, but is associated with higher rates of toxicities. Acute, clinically significant esophagitis or pneumonitis can occur in one in five patients. The risks of esophagitis and pneumonitis can impact the decision to deliver concurrent therapy and limit the total dose of radiation therapy that is delivered. Hematologic toxicities and emesis are common toxicities from systemic therapies for LA-NSCLC and can result in delaying chemotherapy dosing or chemotherapy dose reductions. Late treatment morbidities, including pulmonary fibrosis and cardiac …


Linking Spinal Cord Injury Rehabilitation Between The World Wars: The R. Tait Mckenzie Legacy., John F. Ditunno, Jr Sep 2017

Linking Spinal Cord Injury Rehabilitation Between The World Wars: The R. Tait Mckenzie Legacy., John F. Ditunno, Jr

Department of Rehabilitation Medicine Faculty Papers

Spinal cord injury (SCI) medicine emerged after World War II due to mass casualties, which required specialized treatment centers. This approach to categorical care, however, was first developed during World War I, led by pioneers R. Tait McKenzie and George Deaver, who demonstrated that soldiers disabled by paralysis could return to society through fitness/mobility, recreational and vocational training. McKenzie, a Canadian and the first professor of physical therapy in the US, influenced Deaver and military physicians in Britain, Canada, and the U.S. with his achievements and publications. Although early mortality from SCI was high, advances in the treatment of skin …


Culture Of Mobility, Beth Colborn, Dpt, Helene Daly, Msn, Rn, Kathleen Hilbert, Rn, Msn, Cm, Gordon R. Reeves, Md, Jessica Shank, Pt, Mpt, Elizabeth Singh, Dpt, Lisa Wus, Dnp, Rn, Crnp, Pccn-Cmc Sep 2017

Culture Of Mobility, Beth Colborn, Dpt, Helene Daly, Msn, Rn, Kathleen Hilbert, Rn, Msn, Cm, Gordon R. Reeves, Md, Jessica Shank, Pt, Mpt, Elizabeth Singh, Dpt, Lisa Wus, Dnp, Rn, Crnp, Pccn-Cmc

Department of Rehabilitation Medicine Posters

Objectives

•Create an interdisciplinary approach to patient mobility and functional independence

•Provide education and support to lead a culture of mobility

•Develop a system that reduces immobility related adverse outcomes and promotes overall patient well-being

•Utilize evidence based practice to create a program that will decrease variation in patient care in order to optimize hospital based outcomes


Prisons As Learning Environments For Nursing And Public Health Practice, Mary Bouchaud, Phd, Rn, Madeline Brooks Sep 2017

Prisons As Learning Environments For Nursing And Public Health Practice, Mary Bouchaud, Phd, Rn, Madeline Brooks

College of Nursing Posters

Background:

Challenges in Securing Community Nursing Rotation Sites Eighteen years of providing clinical placement for Bachelor of Science in Nursing (BSN) students has demonstrated that community-based educational opportunities are shrinking due to:

•Increased regulatory requirements

•Competing numbers of nursing schools

•Increasing student enrollment

•Decreasing availability of community resources capable and willing to precept students

These issues present challenges to preparing students for nursing practice. A college of nursing at an urban, academic health center found a solution by working with unexpected partners – maximum security prisons and juvenile detention centers.

A Novel Solution: Partnerships with Prisons

Several factors make prisons …


Serum D-Dimer Test Is Promising For The Diagnosis Of Periprosthetic Joint Infection And Timing Of Reimplantation., Alisina Shahi, Michael M. Kheir, Majd Tarabichi, Hamid R.S. Hosseinzadeh, Timothy L. Tan, Javad Parvizi Sep 2017

Serum D-Dimer Test Is Promising For The Diagnosis Of Periprosthetic Joint Infection And Timing Of Reimplantation., Alisina Shahi, Michael M. Kheir, Majd Tarabichi, Hamid R.S. Hosseinzadeh, Timothy L. Tan, Javad Parvizi

Rothman Institute Papers

BACKGROUND: Despite the availability of a battery of tests, the diagnosis of periprosthetic joint infection (PJI) continues to be challenging. Serum D-dimer assessment is a widely available test that detects fibrinolytic activities that occur during infection. We hypothesized that patients with PJI may have a high level of circulating D-dimer and that the presence of a high level of serum D-dimer may be a sign of persistent infection in patients awaiting reimplantation.

METHODS: This prospective study was initiated to enroll patients undergoing primary and revision arthroplasty. Our cohort consisted of 245 patients undergoing primary arthroplasty (n = 23), revision for …


The Biogenesis Pathway Of Trna-Derived Pirnas In Bombyx Germ Cells., Shozo Honda, Takuya Kawamura, Phillipe Loher, Keisuke Morichika, Isidore Rigoutsos, Yohei Kirino, Phd Sep 2017

The Biogenesis Pathway Of Trna-Derived Pirnas In Bombyx Germ Cells., Shozo Honda, Takuya Kawamura, Phillipe Loher, Keisuke Morichika, Isidore Rigoutsos, Yohei Kirino, Phd

Computational Medicine Center Faculty Papers

Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation. Molecular mechanisms that shape and regulate their expression profiles are largely unknown. Here, we report the mechanism of biogenesis for tRNA-derived Piwi-interacting RNAs (td-piRNAs) expressed in Bombyx BmN4 cells. In the cells, two cytoplasmic tRNA species, tRNAAspGUC and tRNAHisGUG, served as major sources for td-piRNAs, which were derived from the 5'-part of the respective tRNAs. cP-RNA-seq identified the two tRNAs as major substrates for the 5'-tRNA halves …


One Jefferson News September 2017, Performance Excellence Sep 2017

One Jefferson News September 2017, Performance Excellence

One Jefferson News

Over the past three years, we have embarked on an exciting journey of reimagining a new model for health and education to create One Jefferson. Our first step was to bring together Thomas Jefferson University and Thomas Jefferson University Hospital. We continued along this journey by welcoming Abington Health and Aria Health, and combining Philadelphia University and Thomas Jefferson University. Recently, we also welcomed Kennedy Health to the Jefferson Health family.

As the process of coming together – becoming one – continues to produce a growing number of integration successes for the organization, we are expanding communication efforts with this …


A Clinical Practice Guideline For The Management Of Patients With Acute Spinal Cord Injury: Recommendations On The Use Of Methylprednisolone Sodium Succinate, Michael G. Fehlings, Jefferson R. Wilson, Lindsay A. Tetreault, Bizhan Aarabi, Paul A. Anderson, Paul M. Arnold, Darrel S. Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory W. Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark R. Kotter, Shekar N. Kurpad, Brian Kwon, Ralph J. Marino, Allan R. Martin, Eric M. Massicotte, Geno J. Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Andrea C. Skelly, Anoushka Singh, Eve Tsai, Alexander R. Vaccaro, Albert Yee, James S. Harrop Sep 2017

A Clinical Practice Guideline For The Management Of Patients With Acute Spinal Cord Injury: Recommendations On The Use Of Methylprednisolone Sodium Succinate, Michael G. Fehlings, Jefferson R. Wilson, Lindsay A. Tetreault, Bizhan Aarabi, Paul A. Anderson, Paul M. Arnold, Darrel S. Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory W. Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark R. Kotter, Shekar N. Kurpad, Brian Kwon, Ralph J. Marino, Allan R. Martin, Eric M. Massicotte, Geno J. Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Andrea C. Skelly, Anoushka Singh, Eve Tsai, Alexander R. Vaccaro, Albert Yee, James S. Harrop

Department of Rehabilitation Medicine Faculty Papers

Introduction: The objective of this guideline is to outline the appropriate use of methylprednisolone sodium succinate (MPSS) in patients with acute spinal cord injury (SCI). Methods: A systematic review of the literature was conducted to address key questions related to the use of MPSS in acute SCI. A multidisciplinary Guideline Development Group used this information, in combination with their clinical expertise, to develop recommendations for the use of MPSS. Based on GRADE (Grading of Recommendation, Assessment, Development and Evaluation), a strong recommendation is worded as “we recommend,” whereas a weaker recommendation is indicated by “we suggest.” Results: The main conclusions …


Type And Timing Of Rehabilitation Following Acute And Subacute Spinal Cord Injury: A Systematic Review, Anthony S. Burns, Ralph J. Marino, Sukhvinder Kalsi-Ryan, James W. Middleton, Lindsay A. Tetreault, Joseph R. Dettori, Kathryn E. Mihalovich, Michael G. Fehlings Sep 2017

Type And Timing Of Rehabilitation Following Acute And Subacute Spinal Cord Injury: A Systematic Review, Anthony S. Burns, Ralph J. Marino, Sukhvinder Kalsi-Ryan, James W. Middleton, Lindsay A. Tetreault, Joseph R. Dettori, Kathryn E. Mihalovich, Michael G. Fehlings

Department of Rehabilitation Medicine Faculty Papers

Objectives: The objective of this study was to conduct a systematic review of the literature to address the following clinical questions: In adult patients with acute and subacute complete or incomplete traumatic SCI, (1) does the time interval between injury and commencing rehabilitation affect outcome?; (2) what is the comparative effectiveness of different rehabilitation strategies, including different intensities and durations of treatment?; (3) are there patient or injury characteristics that affect the efficacy of rehabilitation?; and (4) what is the cost-effectiveness of various rehabilitation strategies? Methods: A systematic search was conducted for literature published through March 31, 2015 that evaluated …


A Clinical Practice Guideline For The Management Of Patients With Acute Spinal Cord Injury: Recommendations On The Role Of Baseline Magnetic Resonance Imaging In Clinical Decision Making And Outcome Prediction, Michael G. Fehlings, Allan R. Martin, Lindsay A. Tetreault, Bizhan Aarabi, Paul Anderson, Paul M. Arnold, Darrel Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark Kotter, Shekar Kurpad, Brian K. Kwon, Ralph J. Marino, Eric Massicotte, Geno J. Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Anoushka Singh, Andrea C. Skelly, Eve C. Tsai, Alexander R. Vaccaro, Jefferson R. Wilson, Albert Yee, James Harrop Sep 2017

A Clinical Practice Guideline For The Management Of Patients With Acute Spinal Cord Injury: Recommendations On The Role Of Baseline Magnetic Resonance Imaging In Clinical Decision Making And Outcome Prediction, Michael G. Fehlings, Allan R. Martin, Lindsay A. Tetreault, Bizhan Aarabi, Paul Anderson, Paul M. Arnold, Darrel Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark Kotter, Shekar Kurpad, Brian K. Kwon, Ralph J. Marino, Eric Massicotte, Geno J. Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Anoushka Singh, Andrea C. Skelly, Eve C. Tsai, Alexander R. Vaccaro, Jefferson R. Wilson, Albert Yee, James Harrop

Department of Rehabilitation Medicine Faculty Papers

Introduction: The objective of this guideline is to outline the role of magnetic resonance imaging (MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury (SCI). Methods: A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI. This review focused on longitudinal studies that controlled for baseline neurologic status. A multidisciplinary Guideline Development Group (GDG) used this information, their clinical expertise, and patient input to develop recommendations on the use of MRI for SCI patients. Based on GRADE (Grading of Recommendation, Assessment, …


A Clinical Practice Guideline For The Management Of Patients With Acute Spinal Cord Injury: Recommendations On The Type And Timing Of Anticoagulant Thromboprophylaxis, Michael G. Fehlings, Lindsay A. Tetreault, Bizhan Aarabi, Paul Anderson, Paul M. Arnold, Darrel S. Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark Kotter, Shekar Kurpad, Brian K. Kwon, Ralph J. Marino, Allan R. Martin, Eric Massicotte, Geno J. Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Anoushka Singh, Andrea C. Skelly, Eve C. Tsai, Alexander R. Vaccaro, Jefferson R. Wilson, Albert Yee, James Harrop Sep 2017

A Clinical Practice Guideline For The Management Of Patients With Acute Spinal Cord Injury: Recommendations On The Type And Timing Of Anticoagulant Thromboprophylaxis, Michael G. Fehlings, Lindsay A. Tetreault, Bizhan Aarabi, Paul Anderson, Paul M. Arnold, Darrel S. Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark Kotter, Shekar Kurpad, Brian K. Kwon, Ralph J. Marino, Allan R. Martin, Eric Massicotte, Geno J. Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Anoushka Singh, Andrea C. Skelly, Eve C. Tsai, Alexander R. Vaccaro, Jefferson R. Wilson, Albert Yee, James Harrop

Department of Rehabilitation Medicine Faculty Papers

Introduction: The objective of this study is to develop evidence-based guidelines that recommend effective, safe and cost-effective thromboprophylaxis strategies in patients with spinal cord injury (SCI). Methods: A systematic review of the literature was conducted to address key questions relating to thromboprophylaxis in SCI. Based on GRADE (Grading of Recommendation, Assessment, Development and Evaluation), a strong recommendation is worded as “we recommend,” whereas a weaker recommendation is indicated by “we suggest.” Results: Based on conclusions from the systematic review and expert panel opinion, the following recommendations were developed: (1) “We suggest that anticoagulant thromboprophylaxis be offered routinely to reduce the …


A Clinical Practice Guideline For The Management Of Patients With Acute Spinal Cord Injury And Central Cord Syndrome: Recommendations On The Timing (≤24 Hours Versus >24 Hours) Of Decompressive Surgery, Michael G. Fehlings, Lindsay A. Tetreault, Jefferson R. Wilson, Bizhan Aarabi, Paul Anderson, Paul M. Arnold, Darrel S. Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark Kotter, Shekar Kurpad, Ralph J. Marino, Allan R. Martin, Eric Massicotte, Geno J. Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Anoushka Singh, Andrea C. Skelly, Eve C. Tsai, Alexander R. Vaccaro, Albert Yee, James S. Harrop Sep 2017

A Clinical Practice Guideline For The Management Of Patients With Acute Spinal Cord Injury And Central Cord Syndrome: Recommendations On The Timing (≤24 Hours Versus >24 Hours) Of Decompressive Surgery, Michael G. Fehlings, Lindsay A. Tetreault, Jefferson R. Wilson, Bizhan Aarabi, Paul Anderson, Paul M. Arnold, Darrel S. Brodke, Anthony S. Burns, Kazuhiro Chiba, Joseph R. Dettori, Julio C. Furlan, Gregory Hawryluk, Langston T. Holly, Susan Howley, Tara Jeji, Sukhvinder Kalsi-Ryan, Mark Kotter, Shekar Kurpad, Ralph J. Marino, Allan R. Martin, Eric Massicotte, Geno J. Merli, James W. Middleton, Hiroaki Nakashima, Narihito Nagoshi, Katherine Palmieri, Anoushka Singh, Andrea C. Skelly, Eve C. Tsai, Alexander R. Vaccaro, Albert Yee, James S. Harrop

Department of Rehabilitation Medicine Faculty Papers

Objective: To develop recommendations on the timing of surgical decompression in patients with traumatic spinal cord injury (SCI) and central cord syndrome. Methods: A systematic review of the literature was conducted to address key relevant questions. A multidisciplinary guideline development group used this information, along with their clinical expertise, to develop recommendations for the timing of surgical decompression in patients with SCI and central cord syndrome. Based on GRADE, a strong recommendation is worded as “we recommend,” whereas a weak recommendation is presented as “we suggest.” Results: Conclusions from the systematic review included (1) isolated studies reported statistically significant and …