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Full-Text Articles in Medicine and Health Sciences

The Structure, Mortality And Growth Of The Tench [Tinca Tinca (L., 1758)] Population In Çivril Lake, Denizli, Turkey, Süleyman Balik, Hasan M. Sari, Mustafa Ruşen Ustaoğlu, Ali̇ İlhan Jan 2004

The Structure, Mortality And Growth Of The Tench [Tinca Tinca (L., 1758)] Population In Çivril Lake, Denizli, Turkey, Süleyman Balik, Hasan M. Sari, Mustafa Ruşen Ustaoğlu, Ali̇ İlhan

Turkish Journal of Veterinary & Animal Sciences

The population structure, mortality and growth of the tench [Tinca tinca (L., 1758)] in Çivril Lake was investigated, using 506 fish caught with various gill nets between February 1998 and January 1999. The percentages of females and males in the population were 38.34% and 61.66%, respectively, and the overall female-male sex ratio was 1:1.61. Specimens ranged from 11.4 to 28.8 cm in fork length, and from 27.7 to 420.4 g in weight. The age distribution was I-V in the population. For all individuals, the length-weight relation and von Bertalanffy growth parameters were W = 0.018 L^{3.01}, and L_{\infity} = 33.85 …


Some Growth Characteristics Of The Brown Trout Salmo Trutta Macrostigma (Dumeril, 1858) In Tekederesi (Erzurum), Esat Mahmut Kocaman, Aslan Yusuf Yüksel, Muhammed Atamanalp Jan 2004

Some Growth Characteristics Of The Brown Trout Salmo Trutta Macrostigma (Dumeril, 1858) In Tekederesi (Erzurum), Esat Mahmut Kocaman, Aslan Yusuf Yüksel, Muhammed Atamanalp

Turkish Journal of Veterinary & Animal Sciences

Some growth properties of the brown trout Salmo trutta macrostigma (Dumeril, 1858) in Tekederesi, which is a branch feeding the Karasu River, were investigated. The age composition of the population varied between I and V. The population was 64.81% female and 35.19% male and the differences between the sexes were statistcally significant (P < 0.05). The mean fork length and mean body weight of the 54 individuals examined were 16.58 cm and 53.15 g, respectively. The differences between the sexes according to age groups for fork length and total weight were not statistically significant (P > 0.05). The specific and relative growth for length and weight were maximum at the second age. The length-weight relationship of the population was calculated by the least squares method and the logarithmic equation was found to be Log W = -1.4684 + 2.590 Log FL (fork length). …


A Study On The Meat Cost And Marketing Margins Of Cattle Fattening Farms In Erzurum Province, Yavuz Topcu Jan 2004

A Study On The Meat Cost And Marketing Margins Of Cattle Fattening Farms In Erzurum Province, Yavuz Topcu

Turkish Journal of Veterinary & Animal Sciences

The major aim of this study was to analyze the meat cost per kg live weight and marketing margins of cattle fattening farms in Erzurum province in the 2001 production period. Data were collected from 130 cattle fattening farms and different associations. Cattle fattening farms were classified according to their size into 3 groups using stratified random sampling. According to the results obtained, the meat cost per kg live weight was 2.800.000 TL for group 1 farms, 2.840.000 TL for group 2 farms and 2.290.000 TL for group 3 farms. Marketing margins were 33.33% for group 1 and 3 farms …


The Quality Changes That Occur During The Frozen Storage Of Bonito (Sarda Sarda Bloch, 1793) Prepared By Different Treatments, Hülya Turan, İbrahi̇m Erkoyuncu Jan 2004

The Quality Changes That Occur During The Frozen Storage Of Bonito (Sarda Sarda Bloch, 1793) Prepared By Different Treatments, Hülya Turan, İbrahi̇m Erkoyuncu

Turkish Journal of Veterinary & Animal Sciences

Bonitos (Sarda sarda Bloch, 1793) frozen with different prefreezing and postfreezing treatments at -35 ºC in an air blast freezer with 5 m/s air velocity were stored at -25,2 ºC for 6 months. We determined the effects on the sensory properties, total volatile basic nitrogen (TVB-N) and thiobarbituric acid (TBA) values, and the drip loss during the storage period of applying glaze with solution including ascorbic acid for preventing oxidation, of using sodium polyphosphate in order to prevent drip loss during the frozen storage, of removing the internal organs and gills, and of keeping in ice during 24 h prefreezing. …


Changes In Meat Yield And Food Component Of Smoked Tench (Tinca Tinca L., 1758), Levent İzci̇, Ö. Osman Ertan Jan 2004

Changes In Meat Yield And Food Component Of Smoked Tench (Tinca Tinca L., 1758), Levent İzci̇, Ö. Osman Ertan

Turkish Journal of Veterinary & Animal Sciences

In this study, changes in the food component and meat yield in hot smoked tench (Tinca tinca L., 1758) were investigated. The meat yield of tench was calculated as 49.27 ± 0.76%. Before hot smoking the water content, and crude fat, crude protein, crude ash and carbohydrate levels were determined as 83.19 ± 0.56%, 1.11 ± 0.05%, 12.68 ± 0.57%, 1.13 ± 0.10% and 1.89 ± 0.14%, respectively. After hot smoking the water content and crude fat, crude protein, cude ash and carbohydrate levels were determined as 73.59 ± 0.35%, 1.56 ± 0.13%, 18.38 ± 0.64%, 4.29 ± 0.26% and …


Estimation Of Genetic Parameters And Correlations For The First Three Lactation Milk Yields In Holstein Friesian Cattle By The Reml Method, Adnan Ünalan, Zeynel Cebeci̇ Jan 2004

Estimation Of Genetic Parameters And Correlations For The First Three Lactation Milk Yields In Holstein Friesian Cattle By The Reml Method, Adnan Ünalan, Zeynel Cebeci̇

Turkish Journal of Veterinary & Animal Sciences

In this study, 3484 milk yield records (1520 first, 1206 second and 758 third lactations) obtained from 1816 cows born between 1990 and 1997 in the Holstein-Friesian herd of Ceylanpınar State Farm were used to estimate the heritabilities, and genetic and phenotypic correlations between lactation milk yields using an individual animal model and the restricted maximum likelihood (REML) method. In the model studied, 305-day milk yields were used and individual animal effects were assumed to be a random effect, calving year and calving months were fixed effects, and calving age (as months) was a covariate, and all of these factors …


The Effect Of Gnrh Administration On Plasma Progesterone And Reproductive Performance In Ewes, Mehmet Aki̇f Çam, Mehmet Kuran, Erdoğan Selçuk Jan 2004

The Effect Of Gnrh Administration On Plasma Progesterone And Reproductive Performance In Ewes, Mehmet Aki̇f Çam, Mehmet Kuran, Erdoğan Selçuk

Turkish Journal of Veterinary & Animal Sciences

Two experiments were carried out to investigate the effect of GnRH administration at mating and on day 12 post-mating on the reproductive performance of Karayaka and Sakız x Karayaka (F_2) crossbred sheep. In the first experiment, ewes were allocated into a control group (K, n = 27), and groups administered 4 µg GnRH at mating (A, n = 27), on day 12 post-mating (AS, n = 30) and both at mating and on day 12 post-mating (AAS, n = 30). GnRH administration in the A and AS groups increased plasma progesterone concentrations (P < 0.01). The pregnancy rate at first mating in the AS group (86.7%) was higher than those in the ASS (66.7%), A (51.9%) and K (51.9%) groups (P < 0.01). There was no difference between the treatment groups in terms of litter sizes (1.31, 1.21, 1.21 and 1.20 for AS, K, A and ASS, respectively). In the second experiment, ewes were allocated into 2 groups, a control group (K, n = 70) and a group administered 4 µg GnRH on day 12 post-mating (AS, n = 73). The pregnancy rate at first mating was 71.4% and 80.8% (P > 0.05) and litter size was 1.24 and …


Microbiological Quality And Chemical Composition Of The Döner, Vi̇ldan Küpeli̇ Gençer, Mükerrem Kaya Jan 2004

Microbiological Quality And Chemical Composition Of The Döner, Vi̇ldan Küpeli̇ Gençer, Mükerrem Kaya

Turkish Journal of Veterinary & Animal Sciences

Chemical composition and microbiological quality of 40 döner samples (cooked) taken from 8 different restaurants in Erzurum city center were investigated. Total aerobic bacteria count was an average of 5.1 log CFU/g. Lactic acid bacteria counts in 20% of samples, Enterobacteriaceae and S. aureus counts in 60% of samples, coliform bacteria counts in 45% of samples, E. coli counts in 67.5% of samples, and C. perfringens count in 85% of samples were under detectable levels (


The Behavior Of Listeria Monocytogenes In Sucuks Produced With Different Lactic Starter Cultures, Mükerrem Kaya, Hüsnü Yusuf Gökalp Jan 2004

The Behavior Of Listeria Monocytogenes In Sucuks Produced With Different Lactic Starter Cultures, Mükerrem Kaya, Hüsnü Yusuf Gökalp

Turkish Journal of Veterinary & Animal Sciences

In this study, the growth and viability status of Listeria monocytogenes were investigated during the ripening and storage period of sucuk (Turkish dry fermented sausage) produced using different lactic acid bacteria (Lactobacillus plantarum Lb 8 and L. plantarum Lb 75, Pediococcus acidilactici Lb 626, P. pentosaceus Lb 1010, L. sakei 706 and L. sakei 706-B). The initial inoculum of L. monocytogenes into sucuk dough was 10^4 cfu/g. There was a significant increase in the L. monocytogenes counts during the first 3 days of ripening of sucuk produced without starter culture. A similar result was observed in sucuk fermented with L. …


Determination Of Variations In Fish Growth During Reservoir Ontogeny: A Case Study Of The Mirror Carp Population In Gelingüllü Dam Lake (Yozgat, Turkey), Fi̇tnat Güler Ekmekçi̇, Şeri̇fe Gülsün Kirankaya Jan 2004

Determination Of Variations In Fish Growth During Reservoir Ontogeny: A Case Study Of The Mirror Carp Population In Gelingüllü Dam Lake (Yozgat, Turkey), Fi̇tnat Güler Ekmekçi̇, Şeri̇fe Gülsün Kirankaya

Turkish Journal of Veterinary & Animal Sciences

Reservoirs are unstable environments as a very rapid change from a riverine to lacustrine environment occurs in terms of hydrology, climatology and ecology. These changes have a very significant influence on the growth and reproduction of fish populations. In this study, the effects of different phases of reservoir ontogeny on fish growth in Gelingüllü Dam Lake, a typical Central Anatolian reservoir, were monitored. The growth of mirror carp introduced into Gelingüllü Dam Lake was studied both during an initial phase, from 1995 to 1996, and during a later pre-depression phase, from 1998 to 2000. The growth parameters were compared in …


Antimicrobial Activity And Characteristics Of Bacteriocins Produced By Vaginal Lactobacilli, Şengül Alpay Karaoğlu, Faruk Aydi̇n, S. Sirri Kiliç, Ali̇ O. Kiliç Jan 2003

Antimicrobial Activity And Characteristics Of Bacteriocins Produced By Vaginal Lactobacilli, Şengül Alpay Karaoğlu, Faruk Aydi̇n, S. Sirri Kiliç, Ali̇ O. Kiliç

Turkish Journal of Medical Sciences

The aim of this study is to test the production of bacteriocin in vaginal Lactobacilli and determining the characterization and antibacterial activity of this bacteriocin. For this reason 100 Lactobacillus strains were isolated and identified from vaginal swab samples of 75 women who attended obstetric and gynecology clinics. It was determined that six of 100 Lactobacillus strains produced bacteriocin. The antibacterial activity of bacteriocins was examined and found to be effective on vaginal L. gasseri, L. acidophilus, Gardnerella vaginalis ATCC 14018 and Pseudomonas aeroginosa ATCC 10145. We also found that bacteriocins were sensitive to proteinase enzymes and alkalinity, but resistant …


Diagnostic Value Of Ki-67li In Hepatocellular Carcinoma Ki-67 Antigen Expression In Hepatocellular Carcinoma, Metastatic Adenocarcinoma And Normal Hepatocytes, Işin Soyuer, Cemi̇l Eki̇nci̇, Muhsi̇n Kaya, Yasemi̇n Genç, Kadi̇r Bahar Jan 2003

Diagnostic Value Of Ki-67li In Hepatocellular Carcinoma Ki-67 Antigen Expression In Hepatocellular Carcinoma, Metastatic Adenocarcinoma And Normal Hepatocytes, Işin Soyuer, Cemi̇l Eki̇nci̇, Muhsi̇n Kaya, Yasemi̇n Genç, Kadi̇r Bahar

Turkish Journal of Medical Sciences

One hundred liver fine-needle aspiration cytology (FNAC) specimens obtained from 42 patients with hepatocellular carcinomas (HCC), 38 patients with metastatic adenocarcinomas (MAC) and 20 patients with non-malignant liver disease (control group) were studied. Liver specimens were stained with an immunoperoxidase method using a monoclonal antibody to Ki-67 (MIB1). Ki-67 antigen was visualised in cold acetone, and a fresh liver needle aspiration cytology specimen using antibodies was used to identify proliferating hepatocytes. In this study it was examined that; if there is a difference between the groups in terms of Ki-67 positivity and degree of differentiation of tumor and the relationship …


Prevalence Of Oral Precancerous Lesions In A Selected Turkish Population, Çağri Deli̇lbaşi, Hakan Akman, Eni̇s Redzep, Ümi̇t K. Akal Jan 2003

Prevalence Of Oral Precancerous Lesions In A Selected Turkish Population, Çağri Deli̇lbaşi, Hakan Akman, Eni̇s Redzep, Ümi̇t K. Akal

Turkish Journal of Medical Sciences

Oral cancers are malignancies that have high metastasis potential and thus survival rate of the patients is low. Today, epidemiological studies are being widely conducted on precancerous lesions, defined as predecessor lesions. In order to investigate the prevalence of oral precancerous lesions among Turkish people, 2000 consecutive outpatients who referred to our clinic for routine dental treatment, were examined. The proportion of lesions with potential to transform into cancer was 4.0%. It was concluded that leukoplakia and lichen planus were the most commonly observed precancerous lesions. All lesions had male propensity and the most affected site was the buccal mucosa. …


Immunization Of Mice With Plasmid Dna Encoding Hepatitis B Virus Core Antigen (Hbcag), Yasemi̇n Bulut, Hakan Bulut, Mehmet Zi̇ya Doymaz Jan 2003

Immunization Of Mice With Plasmid Dna Encoding Hepatitis B Virus Core Antigen (Hbcag), Yasemi̇n Bulut, Hakan Bulut, Mehmet Zi̇ya Doymaz

Turkish Journal of Medical Sciences

The aim of this study was to investigate the antibody response following immunization with plasmid vector DNA containing the hepatitis B virus core antigen (HBcAg) gene of a hepatitis B virus (HBV) isolated from a patient in Turkey. A HBcAg gene fragment was cloned into a pcDNA 3 eukaryotic expression vector. After confirmation of the cloning of the HBcAg gene, the expressing vector based HBcAg was used in DNA immunization experiments. Four-to 6-week-old Balb/c mice were immunized with HBcAg expressing plasmids and the anti-HBcAg antibody responses of the mice were evaluated by enzyme immunoassay (EIA). The results of this study …


Evaluation Of Phagocytic Function Of The Spleen After Splenic Artery Ligation In Secondary Hypersplenism, Celaletti̇n Vatansev, Şaki̇r Teki̇n, Mustafa Şahi̇n, Mustafa Serdengeçti̇, Mustafa C. Avunduk Jan 2003

Evaluation Of Phagocytic Function Of The Spleen After Splenic Artery Ligation In Secondary Hypersplenism, Celaletti̇n Vatansev, Şaki̇r Teki̇n, Mustafa Şahi̇n, Mustafa Serdengeçti̇, Mustafa C. Avunduk

Turkish Journal of Medical Sciences

The aim of this study was to investigate the effects of splenic artery ligation on the phagocytic functions and morphology of the spleen in rabbits in which secondary hypersplenism was induced by splenic vein ligation (SVL). Thirty New Zealand-type rabbits were included in this study. The rabbits were separated into three groups of 10 subjects each. The first group underwent laparotomy, and the second and third groups underwent laparotomy + splenic vein ligation. At the end of the fourth week, the first and second groups underwent laparotomy while the third group underwent laparotomy + splenic artery ligation. At the end …


Problems In Urinary Iodine Determination Methods And An Automated Kinetic Assay As A Solution, Mustafa Gültepe, Ömer Özcan, Osman Meti̇n İpçi̇oğlu, Kadi̇r Avşar Jan 2003

Problems In Urinary Iodine Determination Methods And An Automated Kinetic Assay As A Solution, Mustafa Gültepe, Ömer Özcan, Osman Meti̇n İpçi̇oğlu, Kadi̇r Avşar

Turkish Journal of Medical Sciences

Accurate, fast and economical urinary iodine measurement is very important in diagnosing iodine deficiency disorders. The urinary iodine determination method using ammonium persulfate digestion based on the Sandell-Kolthoff reaction was optimized and modified to kinetic and automated assay. Ammonium persulfate digestion was performed at +95 ºC in a water-bath to ± 0.1 ºC precision. The performance of both the Sandell-Kolthoff reaction at 37 ºC and its kinetic measurement at 340 nm was tested in a random access automated analyzer. For method comparison, urinary iodine concentrations were measured using both the conventional chloric acid digestion method and the kinetic automated method …


Pcr Analysis Of Hsv-Negative Erythema Multiforme For The Expression Of Other Herpesviruses, Mukadder Koçak, Emel Erkek, Özgül Kisa, Çakir Güney, Ahu Bi̇rol Jan 2003

Pcr Analysis Of Hsv-Negative Erythema Multiforme For The Expression Of Other Herpesviruses, Mukadder Koçak, Emel Erkek, Özgül Kisa, Çakir Güney, Ahu Bi̇rol

Turkish Journal of Medical Sciences

Background: Herpes simplex virus (HSV) is the primary herpesvirus implicated to have a causal role in erythema multiforme (EM), both in cases with an antecedent herpetic infection and in idiopathic EM. However, the association of EM with several other viral infections has been clearly documented. Objective: The aim of the present study was to investigate a hypothetical role for the remaining members of the herpesvirus family in HSV-negative cases of EM. Methods: Fresh, unfixed lesional skin biopsies from 25 patients with HSV-negative EM were studied for the presence of Epstein-Barr virus (EBV), cytomegalovirus (CMV), human herpesvirus-6 (HHV-6) and human herpesvirus-7 …


Lipid Peroxidation, Nitrate And Nitrite Levels In Eclamptic And Intrauterine Growth Retarded Pregnancies, Hati̇ce Paşaoğlu, Nesli̇han Bukan, Gülsen Bulduk, Şevki̇ Çelen Jan 2003

Lipid Peroxidation, Nitrate And Nitrite Levels In Eclamptic And Intrauterine Growth Retarded Pregnancies, Hati̇ce Paşaoğlu, Nesli̇han Bukan, Gülsen Bulduk, Şevki̇ Çelen

Turkish Journal of Medical Sciences

In this study we investigated nitric oxide metabolites nitrate+nitrite and lipid peroxidation product (malonyldialdehyde: MDA) related to the pathogenesis of eclampsia and intrauterine growth retarded (IUGR) pregnancy. Plasma nitrate+nitrite levels were higher in the eclamptic (31.6 ± 16.7 µmol/L p < 0.001) and IUGR (24.3 ± 9.5 µmol/L p < 0.005) groups than in the control group (18.8 ± 6.9 µmol /L). Plasma MDA levels were higher in the eclamptic group (5.5 ± 2.5 nmol/ml (p < 0.05) but not significantly different in the IUGR (3.4 ± 2.4 nmol/ml p > 0.05) group than control group (3.0 ± 1.3 nmol/ml). In addition, the plasma nitrite+nitrate and MDA levels in the eclamptic group were higher than in the IUGR group (p < 0.05). These variations could play different roles in the pathogenesis of eclampsia and IUGR pregnancy.


Lecithin:Cholesterol Acyltransferase Activity And Cholesteryl Ester Transfer Rate In Patients With Diabetes Mellitus, Melahat Di̇ri̇can, Zehra Serdar, Emre Sarandöl, Esma Sürmen Gür Jan 2003

Lecithin:Cholesterol Acyltransferase Activity And Cholesteryl Ester Transfer Rate In Patients With Diabetes Mellitus, Melahat Di̇ri̇can, Zehra Serdar, Emre Sarandöl, Esma Sürmen Gür

Turkish Journal of Medical Sciences

Several factors may be responsible for the high prevalence of atherosclerosis in diabetes mellitus, including alterations in reverse cholesterol transport. In the present study, the activity of plasma lecithin:cholesterol acyltransferase (LCAT) and the cholesteryl ester transfer rate, and concentrations of lipids and lipoproteins were measured in 11 patients with insulin-dependent diabetes mellitus (type 1), 42 patients with noninsulin-dependent diabetes mellitus (type 2) and compared with those in age-matched control groups (Control I, n = 14; and Control II, n = 29, respectively). No statistically significant differences were observed in plasma total cholesterol, triglyceride, ester cholesterol or very low density lipoprotein …


Comparison Of Indirect Methods For Lactose Malabsorption, İsmai̇l Kurt, Mohammed Wael Abou Ghoush, Adnan Haşi̇mi̇, A. Muhi̇tti̇n Serdar, Türker Kutluay Jan 2003

Comparison Of Indirect Methods For Lactose Malabsorption, İsmai̇l Kurt, Mohammed Wael Abou Ghoush, Adnan Haşi̇mi̇, A. Muhi̇tti̇n Serdar, Türker Kutluay

Turkish Journal of Medical Sciences

Although direct determination of the lactase activity of the small intestinal mucosa is considered a "gold standard" for the diagnosis of hypolactasia leading to lactose malabsorption, less invasive and simpler indirect techniques like the "plasma glucose response test" and "breath hydrogen test" are preferred in daily practice to diagnose the disorder. The aim of this study was to compare the different indirect diagnostic methods for lactose malabsorption. The following tests were performed in 54 adults: plasma glucose response test, breath hydrogen test and urine galactose/creatinine ratio. The diagnostic variables were as follows: increased plasma glucose £ 20 mg/dl; increased exhalation …


Subtalar Dislocations: A Report Of Two Cases, Özcan Pehli̇van, Can Solakoğlu, İbrahi̇m Akmaz Jan 2003

Subtalar Dislocations: A Report Of Two Cases, Özcan Pehli̇van, Can Solakoğlu, İbrahi̇m Akmaz

Turkish Journal of Medical Sciences

HLİVAN Can SOLAKOĞLU İbrahim AKMAZ Department of Orthopedics and Traumatology, Gülhane Military Medical Academy, Haydarpaşa Training Hospital, İstanbul - Turkey


Bilateral Intratesticular Varicocele In A Patient With A History Of Bilateral Cryptorchidism, Nuri̇ Erdoğan, Oğuz Ekmekçi̇oğlu, Murat Baykara Jan 2003

Bilateral Intratesticular Varicocele In A Patient With A History Of Bilateral Cryptorchidism, Nuri̇ Erdoğan, Oğuz Ekmekçi̇oğlu, Murat Baykara

Turkish Journal of Medical Sciences

OĞAN^1 Oğuz EKMEKCİOĞLU^2 Murat BAYKARA^1 Departments of ^1Radiology, ^2Urology, Faculty of Medicine, Erciyes University, Kayseri, Turkey


Echinococcus Infestation Of Quadriceps Femoris Muscle Misdiagnosed As A Soft Tissue Tumor (A Case Report), Kaan Erler, Mahmut Kömürcü, M.Taner Özdemi̇r, Uğur Bariş Özkal, Mustafa Başbozkurt, Ömer Günhan Jan 2003

Echinococcus Infestation Of Quadriceps Femoris Muscle Misdiagnosed As A Soft Tissue Tumor (A Case Report), Kaan Erler, Mahmut Kömürcü, M.Taner Özdemi̇r, Uğur Bariş Özkal, Mustafa Başbozkurt, Ömer Günhan

Turkish Journal of Medical Sciences

ER^1 Mahmut KÖMÜRCÜ^1 M.Taner ÖZDEMİR^1 U. Barış ÖZKAL^1 Mustafa BAŞBOZKURT^1 Ömer GÜNHAN^2 Departments of ^1Orthopedics and Traumatology, ^2Pathology Gülhane Military Medical Academy, Etlik, Ankara - TURKEY


Peritoneal Defense Mechanisms, Toni̇ Hau Jan 2003

Peritoneal Defense Mechanisms, Toni̇ Hau

Turkish Journal of Medical Sciences

No abstract provided.


Histological Changes In The Rat Thoracic Aorta After Chronic Nitric Oxide Synthase Inhibition, Ni̇gar Vardi, Feral Öztürk, Ersi̇n Fadillioğlu, Ali̇ Otlu, Murat Yağmurca Jan 2003

Histological Changes In The Rat Thoracic Aorta After Chronic Nitric Oxide Synthase Inhibition, Ni̇gar Vardi, Feral Öztürk, Ersi̇n Fadillioğlu, Ali̇ Otlu, Murat Yağmurca

Turkish Journal of Medical Sciences

The objective of this study was to determine the morphological effects of chronic nitric oxide (NO) inhibition on the thoracic aorta of Wistar rats. Fifteen male Wistar Albino rats were divided into three groups. Group I rats (control group, n = 5) received tap water, group II rats (n = 5) recieved 100 mg/kg L-NAME (moderate NO inhibiton) and group III rats (n = 5) received 500 mg/kg L-NAME, in drinking water (severe NO inhibition) for 15 days. At the end of 15 days, the carotid arteries of the rats were cannulated and their blood pressure was measured. The rats …


A Preliminary Study Of Dna Damage In Peripheral Lymphocytes From Lung Cancer Patients And Healthy Subjects, Arthur See King Sham, Yim Tong Szeto, Iris Frances Foster Benzie, Kian Cheng Tan-Un Jan 2003

A Preliminary Study Of Dna Damage In Peripheral Lymphocytes From Lung Cancer Patients And Healthy Subjects, Arthur See King Sham, Yim Tong Szeto, Iris Frances Foster Benzie, Kian Cheng Tan-Un

Turkish Journal of Medical Sciences

A pilot study was undertaken to investigate the differences in oxidative DNA damage and 2-h DNA repair in peripheral lymphocytes between lung cancer patients and healthy subjects. Twenty-four lung cancer patients and 23 normal controls were recruited from the Queen Mary Hospital, Hong Kong SAR, China. Single cell gel electrophoresis (comet assay) was performed to measure the oxidative damage, repair and baseline of peripheral lymphocytes in the subjects. There were no significant differences in baseline DNA damage and oxidative stress damage and DNA repair at 2 h among the two groups of lung cancer patients who had blood taken before …


Tissue Plasminogen Activator Mass Concentration In Ischemic Acute Stroke Patients, Cavi̇t Boz, Abdurrahman Akbaş, Zekeri̇ya Ali̇oğlu, Mehmet Özmenoğlu Jan 2003

Tissue Plasminogen Activator Mass Concentration In Ischemic Acute Stroke Patients, Cavi̇t Boz, Abdurrahman Akbaş, Zekeri̇ya Ali̇oğlu, Mehmet Özmenoğlu

Turkish Journal of Medical Sciences

The role of endogenous fibrinolysis in cerebral infarction has been investigated, but with conflicting results. In this study, variations of tissue-type plasminogen activator (t-PA) antigen concentrations over time after stroke were examined at the acute and subacute phases of ischemic stroke in a group of patients and in a control group. The relationships between t-PA levels and stroke severity, lesion volume and clinical status were also investigated. This study was carried out in 45 patients with acute ischemic stroke and 21 control subjects who had similar characteristics. Levels of t-PA mass concentration were measured via the ELISA, while Student's t, …


Fasting And Post-Methionine Load Plasma Homocysteine Levels In Patients With Angiographically Defined Coronary Artery Disease, Mustafa Özkan, M. Kemal Erbi̇l, Münzer Al Rashed, Emi̇n Özgür Akgül, Tuncer Çayci, Cumhur Bi̇lgi̇, Gürkan Meti̇nyurt, Şeri̇f Akman, Türker Kutluay Jan 2003

Fasting And Post-Methionine Load Plasma Homocysteine Levels In Patients With Angiographically Defined Coronary Artery Disease, Mustafa Özkan, M. Kemal Erbi̇l, Münzer Al Rashed, Emi̇n Özgür Akgül, Tuncer Çayci, Cumhur Bi̇lgi̇, Gürkan Meti̇nyurt, Şeri̇f Akman, Türker Kutluay

Turkish Journal of Medical Sciences

Elevated plasma homocysteine concentration either in fasting state or after methionine loading is an independent risk factor for vascular disease. The aim of this study was to evaluate the relationship between fasting total homocysteine (tHcy) and post-methionine load tHcy in healthy control subjects and in patients with angiographically defined coronary artery disease (CAD). Methionine loading has been used to investigate impaired methionine metabolism, especially of the trans-sulphuration pathway. We investigated the effect of methionine excess on total plasma homocysteine in 65 control subjects (44 men and 21 women) who attended a polyclinic of Gülhane Military Medical Academy (GMMA) in Ankara. …


Hemodynamic Changes After Aortopulmonary Separation, Ersi̇n Fadillioğlu, M. Kemal Irmak, Murat Yağmurca, Hasan Erdoğan Jan 2003

Hemodynamic Changes After Aortopulmonary Separation, Ersi̇n Fadillioğlu, M. Kemal Irmak, Murat Yağmurca, Hasan Erdoğan

Turkish Journal of Medical Sciences

The neural crest origin of the aortopulmonary septum has led us to investigate the septum. We designed the present study to assess the hemodynamic changes following aortopulmonary separation in the rat. We freed the ascending aorta from the pulmonary artery by blunt dissection and placed aluminium foil between them in anesthetized, ventilated, open-chest animals and found that the procedure resulted in a slight but significant increase in systolic and diastolic blood pressure and in an insignificant elevation of the heart rate. The hemodynamic deterioration observed after the separation process might be a result of a possible function of the aortopulmonary …


Chemokine Receptor Cxcr4 Expression In The Major Salivary Gland, Çağri Deli̇lbaşi Jan 2003

Chemokine Receptor Cxcr4 Expression In The Major Salivary Gland, Çağri Deli̇lbaşi

Turkish Journal of Medical Sciences

LİLBAŞI Osaka University, Graduate School of Dentistry, First Department of Oral and Maxillofacial Surgery