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Articles 3511 - 3540 of 8080
Full-Text Articles in Medicine and Health Sciences
The Patterns And Clinical Relevance Of Contact Allergen Sensitization In A Pediatric Population With Atopic Dermatitis, Ayşegül Akan, Müge Toyran, Emi̇ne Vezi̇r, Di̇lek Azkur, Ayşenur Kaya, Mustafa Erkoçoğlu, Ersoy Ci̇velek, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş
The Patterns And Clinical Relevance Of Contact Allergen Sensitization In A Pediatric Population With Atopic Dermatitis, Ayşegül Akan, Müge Toyran, Emi̇ne Vezi̇r, Di̇lek Azkur, Ayşenur Kaya, Mustafa Erkoçoğlu, Ersoy Ci̇velek, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş
Turkish Journal of Medical Sciences
Background/aim: Data about contact allergen sensitization (CAS) in children with atopic dermatitis (AD) are limited. The purpose of this study was to identify the frequency and patterns of CAS in children with AD by using a ready-to-use patch test system. Materials and methods: After receiving the history of CAS in the patients, the severity of AD and IgE-mediated allergen sensitization were determined. Results: Of 134 children with AD, 33.8% (n = 45) had at least 1 positive reaction. The most frequent positive reaction was to nickel sulfate (NS) (37.8%, 17/45), followed by methylchloroisothiazolinone (20.0%, 9/45) and thimerosal (15.6%, 7/45). The …
Diabetes Prevalence And Awareness In Adults In The Balçova District In Turkey, Kevser Tari Selçuk, Meli̇h Kaan Sözmen, Belgi̇n Ünal Toğrul
Diabetes Prevalence And Awareness In Adults In The Balçova District In Turkey, Kevser Tari Selçuk, Meli̇h Kaan Sözmen, Belgi̇n Ünal Toğrul
Turkish Journal of Medical Sciences
Background/aim: To determine the prevalence and awareness of diabetes and to evaluate associated factors in a population aged 30 and over in the Balçova district of İzmir, Turkey. Materials and methods: In this cross-sectional study data from 12,915 people who participated in Balçova's Heart Project were evaluated. Diabetes was defined using fasting blood glucose levels according to ADA criteria. Results: Diabetes prevalence was 13.0% and 87.7% of the patients were aware of the condition. Diabetes prevalence was 1.32 times higher in males, 1.31 times higher in individuals with primary school or lower level of education, 1.37 times higher in individuals …
The Effect Of Tramadol And Tramadol + Gabapentin Combination In Patients With Lumbar Disc Herniation After Epidural Steroid Injection, Lütfi̇ye Pi̇rbudak, Hülya Çi̇çek, Mustafa Işik, Yasemi̇n Zer
The Effect Of Tramadol And Tramadol + Gabapentin Combination In Patients With Lumbar Disc Herniation After Epidural Steroid Injection, Lütfi̇ye Pi̇rbudak, Hülya Çi̇çek, Mustafa Işik, Yasemi̇n Zer
Turkish Journal of Medical Sciences
Background/aim: To compare the effects of tramadol-only treatment and tramadol + gabapentin treatment in patients who had received an epidural steroid injection. Materials and methods: Forty patients with hernia disc-originated acute lumbar discogenic pain were evaluated. All patients received a single dose of steroid and local anesthesia mixture epidurally via the lumbar approach. In both groups, Group T (tramadol, n = 20) and Group TG (tramadol + gabapentin, n = 20), the injection dose was adjusted to 4 mL of triamcinolone acetonide and 0.25% bupivacaine mixture. Orally, 75 mg/day tramadol or 75 mg/day tramadol + 900 mg/day gabapentin were added …
The Evaluation Of Hypermetabolic Mediastinal-Hilar Lymph Nodes Determined Bypet/Ct In Pulmonary And Extrapulmonary Malignancies: Correlation With Ebus-Tbna, Zuhal Kandemi̇r, Ayşegül Şentürk, Eli̇f Özdemi̇r, Ni̇lüfer Yildirim, Hati̇ce Canan Hasanoğlu, Mutlay Keski̇n, Şeyda Türkölmez
The Evaluation Of Hypermetabolic Mediastinal-Hilar Lymph Nodes Determined Bypet/Ct In Pulmonary And Extrapulmonary Malignancies: Correlation With Ebus-Tbna, Zuhal Kandemi̇r, Ayşegül Şentürk, Eli̇f Özdemi̇r, Ni̇lüfer Yildirim, Hati̇ce Canan Hasanoğlu, Mutlay Keski̇n, Şeyda Türkölmez
Turkish Journal of Medical Sciences
Background/aim: We aimed to define the optimal SUVmax cut-off value in determination of mediastinal-hilar lymph node metastasis, by comparing positive PET/CT results with the results of endobronchial ultrasound guided transbronchial needle aspiration biopsy (EBUS-TBNA). Materials and methods: Thirty-one patients with malignancy whose PET/CT imaging revealed a hypermetabolic mediastinal and/or hilar lymph node and who had undergone EBUS-TBNA were evaluated retrospectively. Histopathology was regarded as the gold standard. The diagnostic role of PET/CT in mediastinal/hilar lymph node metastasis was investigated and compared with the results of contrast-enhanced CT. Results: When a SUVmax value of 2.5 was used, the sensitivity, positive predictive …
Clinical Characteristics And Prognosis Of Patients With Retinoblastoma: 8-Year Follow-Up, Xin Luo, Huijing Ye, Yun-Gang Ding, Yi Du, Huasheng Yang
Clinical Characteristics And Prognosis Of Patients With Retinoblastoma: 8-Year Follow-Up, Xin Luo, Huijing Ye, Yun-Gang Ding, Yi Du, Huasheng Yang
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate the potential correlation between clinical characteristics and prognosis of patients with retinoblastoma (Rb). Materials and methods: This retrospective study included 314 Rb patients. Clinical data including laterality of eyes, sex, age, presenting signs, lag time, and survival were recorded and analyzed. Results: Leukocoria is the most common clinical presentation of Rb. Patients with isolated leukocoria had shorter lag time and exhibited a high survival rate (85%, 5 years). Patients with strabismus and blurred vision, and who were older and had longer lag time, exhibited an excellent survival rate (100% and 92.3%, …
Mutation Analysis Of 6 Spinocerebellar Ataxia (Sca) Types In Patients From Southern Turkey, Perçi̇n Pazarci, Hali̇l Kasap, Ayşe Fi̇li̇z Koç, Şaki̇r Altunbaşak, Mehmet Ali̇ Erkoç
Mutation Analysis Of 6 Spinocerebellar Ataxia (Sca) Types In Patients From Southern Turkey, Perçi̇n Pazarci, Hali̇l Kasap, Ayşe Fi̇li̇z Koç, Şaki̇r Altunbaşak, Mehmet Ali̇ Erkoç
Turkish Journal of Medical Sciences
Background/aim: Spinocerebellar ataxias (SCAs) are complex clinical and genetically heterogeneous, mostly autosomal dominant neurodegenerative diseases. At present, more than 30 hereditary SCA types have been associated with different gene mutations. In this study, the frequency distribution of the 6 SCA types 1, 2, 3, 6, 7, and 17 in the Turkish population was investigated with respect to clinical features. Materials and methods: 159 patients who received a diagnosis of SCA and 42 healthy controls from Adana, Mersin, Gaziantep, Hatay, and Osmaniye provinces were included in the study. DNA samples were isolated from 2 mL blood samples and the number of …
Neopterin, Homocysteine, And Adma Levels During And After Urticaria Attack, Sali̇m Kemal Tuncer, Ümi̇t Kaldirim, Yusuf Emrah Eyi̇, Ali̇ Osman Yildirim, Şafak Eki̇nci̇, Kemal Kara, Murat Eroğlu, Muzaffer Öztosun, Selahatti̇n Özyürek, Murat Durusu, Mustafa Güleç, Tuncer Çayci, Özcan Altinel, Hüseyi̇n Levent Yamanel
Neopterin, Homocysteine, And Adma Levels During And After Urticaria Attack, Sali̇m Kemal Tuncer, Ümi̇t Kaldirim, Yusuf Emrah Eyi̇, Ali̇ Osman Yildirim, Şafak Eki̇nci̇, Kemal Kara, Murat Eroğlu, Muzaffer Öztosun, Selahatti̇n Özyürek, Murat Durusu, Mustafa Güleç, Tuncer Çayci, Özcan Altinel, Hüseyi̇n Levent Yamanel
Turkish Journal of Medical Sciences
Background/aim: Urticaria is a vascular skin reaction characterized with papules and plaques. Neopterin is accepted as an immunologic marker and an indicator of activation of the immune system. Homocysteine and asymmetric dimethylarginine (ADMA) are the markers of increased vascular resistance. Alteration in vascular resistance has a role in the pathogenesis of urticaria. We aimed to investigate whether there is a relationship between urticaria and neopterin, homocysteine, or ADMA. Materials and methods: The study is designed as a prospective descriptive study and patients with a diagnosis of urticaria in the emergency department were included in the study. Demographic data and characteristics …
Investigation Of The Diagnostic Value Of Chromosome Analysis And Bacterial Artificial Chromosome-Based Array Comparative Genomic Hybridization In Prenatal Diagnosis, Hakan Savli, Seda Eren Keski̇n, Naci̇ Çi̇ne
Investigation Of The Diagnostic Value Of Chromosome Analysis And Bacterial Artificial Chromosome-Based Array Comparative Genomic Hybridization In Prenatal Diagnosis, Hakan Savli, Seda Eren Keski̇n, Naci̇ Çi̇ne
Turkish Journal of Medical Sciences
Background/aim: To investigate the diagnostic value of bacterial artificial chromosome (BAC)-based array comparative genomic hybridization (CGH) and chromosome analysis in prenatal diagnosis. Materials and methods: This study included the chromosome analysis and BAC-based array CGH analysis of 140 amniocentesis samples with prenatal diagnosis indications. Results: Karyotype analysis showed trisomy 21 in 4 patients, trisomy 18 in 5 patients, monosomy X in 1 patient, and other anomalies in 3 patients. The BAC-based array CGH analysis showed 4 patients with trisomy 21, 4 patients with trisomy 18, and 1 patient with monosomy X as a numerical chromosome anomaly, while partial duplication was …
Evaluation Of Oxidant And Antioxidant Status In Patients With Vitamin B12 Deficiency, Teki̇n Güney, Murat Alişik, Sema Akinci, Sali̇m Neşeli̇oğlu, İmdat Di̇lek, Özcan Erel
Evaluation Of Oxidant And Antioxidant Status In Patients With Vitamin B12 Deficiency, Teki̇n Güney, Murat Alişik, Sema Akinci, Sali̇m Neşeli̇oğlu, İmdat Di̇lek, Özcan Erel
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to examine the theory that oxidative stress might have an important mediating effect on the deleterious results of vitamin B12 metabolism deficiency seen throughout the body. Materials and methods: Forty patients with vitamin B12 deficiency and 40 healthy controls were included in the study. Venous blood samples were collected from all participants to evaluate serum vitamin B12, homocysteine, methylmalonic acid, total antioxidant status (TAS), and total oxidant status (TOS) levels in the pre- and posttreatment periods. Results: There were no significant differences in TAS, TOS, or oxidative stress index (OSI) levels between the …
Decreasing The Need For Mechanical Ventilation After Surgery Forretinopathy Of Prematurity: Sedoanalgesia Vs. General Anesthesia, Ayşe Ülgey, Işin Güneş, Adnan Bayram, Recep Aksu, Ci̇hangi̇r Bi̇çer, Fati̇h Uğur, Çağatay Karaca, Adem Boyaci
Decreasing The Need For Mechanical Ventilation After Surgery Forretinopathy Of Prematurity: Sedoanalgesia Vs. General Anesthesia, Ayşe Ülgey, Işin Güneş, Adnan Bayram, Recep Aksu, Ci̇hangi̇r Bi̇çer, Fati̇h Uğur, Çağatay Karaca, Adem Boyaci
Turkish Journal of Medical Sciences
Background/aim: Premature infants experience more respiratory problems after surgical procedures. We aimed to compare general anesthesia with sedation regarding the need for postoperative mechanical ventilation in infants undergoing retinopathy of prematurity (ROP) surgery. Materials and methods: Sixty patients who underwent laser surgery for ROP were included in this study. This study was performed between October 2010 and December 2012. The sedation group (Group S, n = 30) received 1 mg/kg ketamine and 1 mg/kg propofol as a bolus for induction. The patients then received an infusion of 100-150 μg kg-1 min-1 propofol and 0.25 mg kg-1 h-1 ketamine for maintenance. …
Correlation Between Body Mass Index And Semen Quality In Male Infertility Patients, Tang Wen-Hao, Zhuang Xin-Jie, Ma Lu-Lin, Qiao Jie, Hong Kai, Zhao Lian-Ming, Liu De-Feng, Mao Jia-Ming, Zhang Hong-Liang, Zhou Shan-Jie, Jiang Hui
Correlation Between Body Mass Index And Semen Quality In Male Infertility Patients, Tang Wen-Hao, Zhuang Xin-Jie, Ma Lu-Lin, Qiao Jie, Hong Kai, Zhao Lian-Ming, Liu De-Feng, Mao Jia-Ming, Zhang Hong-Liang, Zhou Shan-Jie, Jiang Hui
Turkish Journal of Medical Sciences
Background/aim: The question of whether body mass index (BMI) affects semen quality and male fertility is controversial. The purpose of this research was to determine whether there is a correlation between BMI and semen analysis parameters. Materials and methods: A total of 617 male infertility patients were recruited and separated into 3 groups according to BMI values as follows: normal weight group (n = 334), overweight group (n = 220), and obese group (n = 63). Height and weight were measured and a routine semen analysis was performed for all patients. Results: Significant differences existed in BMI, age, and sperm …
Molecular Characteristics Of Extended Spectrum Ss-Lactamase And Carbapenemase Genes Carried By Carbapenem-Resistant Enterobacter Cloacae In A Chinese University Hospital, Lanying Cui, Jingying Zhao, Juan Lu
Molecular Characteristics Of Extended Spectrum Ss-Lactamase And Carbapenemase Genes Carried By Carbapenem-Resistant Enterobacter Cloacae In A Chinese University Hospital, Lanying Cui, Jingying Zhao, Juan Lu
Turkish Journal of Medical Sciences
Background/aim: In recent years, the increase in the prevalence of carbapenem-resistant Enterobacter cloacae (CREC) has been significant and has become a global problem. The aim of this study is to characterize CREC extended spectrum β-lactamases (ESBLs) and CREC carbapenemase genes and evaluate the risk factors for CREC infections in a university hospital in China. Materials and methods: The identification and assessment of the antimicrobial susceptibility of CREC isolates were performed using a VITEK-2 compact system. Clonal relatedness was investigated by pulsed-field gel electrophoresis (PFGE). β-Lactamase genes were examined using polymerase chain reaction and nucleotide sequencing. Results: A total of 64 …
Pharyngeal Carriage Rate Of Neisseria Meningitidis Before And After Thehajj Pilgrimage, In Zahedan (Southeastern Iran), 2012, Maliheh Metanat, Batool Sharifi-Mood, Sara Sanei-Moghaddam, Nahid Sepehri Rad
Pharyngeal Carriage Rate Of Neisseria Meningitidis Before And After Thehajj Pilgrimage, In Zahedan (Southeastern Iran), 2012, Maliheh Metanat, Batool Sharifi-Mood, Sara Sanei-Moghaddam, Nahid Sepehri Rad
Turkish Journal of Medical Sciences
Background/aim: The annual Hajj pilgrimage to Mecca, which attracts more than 3 million Muslim pilgrims from around the world, has played a role in the global spread of meningococcal infection. We aimed to compare pharyngeal carriage of Neisseria meningitidis in Hajj pilgrims before departure and after returning to Iran, Zahedan. Materials and methods: This prospective and cross-sectional study was conducted among Hajj pilgrims in Zahedan (southeast Iran) in 2012. We studied all pilgrims who agreed to participate in this study and who met the inclusion criteria. Sampling was done by swabbing the posterior pharyngeal wall through the mouth with direct …
Characterization Of Klebsiella Isolates By Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry (Maldi-Tof Ms) And Determination Of Antimicrobial Resistance With Vitek 2 Advanced Expert System (Aes), Alper Karagöz, Sümeyra Acar, Hani̇fi̇ Körkoca
Characterization Of Klebsiella Isolates By Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry (Maldi-Tof Ms) And Determination Of Antimicrobial Resistance With Vitek 2 Advanced Expert System (Aes), Alper Karagöz, Sümeyra Acar, Hani̇fi̇ Körkoca
Turkish Journal of Medical Sciences
Background/aim: The purpose of the study was to evaluate the performance of the VITEK mass spectrometry (MS) (bioMérieux, France) system for the identification of Klebsiella spp. isolated from different sources. Moreover, while assessing the ability of the VITEK 2 automated expert system (AES) to recognize antimicrobial resistance patterns, the researchers have extended the study to compare VITEK 2 with the routine antimicrobial susceptibility testing method. Materials and methods: This study tested 51 Klebsiella spp. isolates that were isolated from environmental examples and clinical examples. Results of conventional methods and the matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) MS were compared. Then, any …
Pcr Investigation Of Panton-Valentine Leukocidin, Enterotoxin, Exfoliative Toxin,And Agr Genes In Staphylococcus Aureus Strains Isolated From Psoriasis Patients, Juli̇de Sedef Göçmen, Neri̇man Şahi̇ner, Mukadder Koçak, Zeynep Ceren Karahan
Pcr Investigation Of Panton-Valentine Leukocidin, Enterotoxin, Exfoliative Toxin,And Agr Genes In Staphylococcus Aureus Strains Isolated From Psoriasis Patients, Juli̇de Sedef Göçmen, Neri̇man Şahi̇ner, Mukadder Koçak, Zeynep Ceren Karahan
Turkish Journal of Medical Sciences
Background/aim: Staphylococcus aureus colonization is a determiner of disease activation in psoriasis patients. Here we evaluate the presence of genes encoding Panton-Valentine leukocidin (PVL), enterotoxins, TSST-1, exfoliative toxins, and the accessory gene regulatory locus by polymerase chain reaction (PCR) in S. aureus isolates obtained from healthy and diseased skin regions and anterior nares of psoriasis patients and healthy controls. Materials and methods: The presence of PVL and toxin genes was investigated, and agr typing was performed by PCR. Results: Eighteen of the isolated strains carried the sei, 1 carried the seb-sec, and 1 carried the seg1397645907enterotoxin gene. Eight of the …
Workplace Physical Violence, Verbal Violence, And Mobbing Experiencedby Nurses At A University Hospital, Fatma Nur Baran Aksakal, Emi̇ne Füsun Karaşahi̇n, Asi̇ye Uğraş Di̇kmen, Emi̇ne Avci, Seçi̇l Özkan
Workplace Physical Violence, Verbal Violence, And Mobbing Experiencedby Nurses At A University Hospital, Fatma Nur Baran Aksakal, Emi̇ne Füsun Karaşahi̇n, Asi̇ye Uğraş Di̇kmen, Emi̇ne Avci, Seçi̇l Özkan
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine the frequency of and risk factors for physical violence, verbal violence, and mobbing experienced by nurses in a university hospital. Materials and methods: This was a cross-sectional study conducted at Gazi University Medical Faculty Hospital. A questionnaire form recommended by the WHO and the International Labor Organization was administered through face-to-face interviews to determine the violence experienced in the past 12 months by nurses. Results: The prevalence of physical violence, verbal violence, and mobbing was 13.9%, 41.8%, and 17.1%, respectively. Working more than 40 h per week increased the risk of …
An Anatomical Study Of The Supratrochlear Foramen Of The Jining Population, Jing Li, Qinghua Mao, Wenyuan Li, Xiaoyan Li
An Anatomical Study Of The Supratrochlear Foramen Of The Jining Population, Jing Li, Qinghua Mao, Wenyuan Li, Xiaoyan Li
Turkish Journal of Medical Sciences
Background/aim: The supratrochlear foramen (STF) is an important variation in the lower end of the humerus where the septum separating the coronoid and olecranon fossa is perforated. There are no studies in the literature on the STF of the Jining population. This study will make a contribution to anatomy and anthropology by adding new data. Materials and methods: STF was studied in detail in 262 adult dried humeri of unknown sex and age. The topographical anatomy of the STF was studied, morphometric measurements were taken, and the specimens were photographed with a digital camera. Results: The prevalence of the STF …
Paclitaxel-Loaded Niosomes For Intravenous Administration: Pharmacokineticsand Tissue Distribution In Rats, Zerri̇n Sezgi̇n Bayindir, Arzu Beşi̇kci̇, Ni̇lüfer Yüksel
Paclitaxel-Loaded Niosomes For Intravenous Administration: Pharmacokineticsand Tissue Distribution In Rats, Zerri̇n Sezgi̇n Bayindir, Arzu Beşi̇kci̇, Ni̇lüfer Yüksel
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to investigate and compare the pharmacokinetic behavior and tissue distribution of paclitaxel, delivered as commercial preparation Taxol or through Span 40 niosomes, after intravenous injection to rats. Materials and methods: Paclitaxel-loaded Span 40 niosomes were prepared using the thin-film method. An HPLC method was developed and validated for paclitaxel determination in rat plasma and tissues. Results: The area under the curve value of the niosome-recipient group (3.22 ± 0.255 μg h/mL) was significantly higher compared to that of the Taxol group (0.725 ± 0.163 μg h/mL). The mean residence time and the elimination …
Comparison Of Thiopental And Ketamine+Xylazine Anesthesia Inischemia/Reperfusion-Induced Arrhythmias In Rats, Ersöz Gonca
Comparison Of Thiopental And Ketamine+Xylazine Anesthesia Inischemia/Reperfusion-Induced Arrhythmias In Rats, Ersöz Gonca
Turkish Journal of Medical Sciences
Background/aim: To investigate the influence of thiopental (85 mg/kg, intraperitoneally (ip)), and ketamine+xylazine (ketamine 75 mg/kg and xylazine 8 mg/kg, ip) anesthesia on the incidence and duration of ischemia/reperfusion-induced arrhythmias. Materials and methods: Myocardial ischemia was induced by a 6-min ligation of the left anterior descending coronary artery, followed by a 6-min reperfusion. Measurements were taken of the incidence and duration of ventricular arrhythmias, the mean arterial blood pressure and heart rate, and the pressure rate-product (as an index of myocardial oxygen consumption). Results: The arrhythmia score and the incidence of ventricular fibrillation and tachycardia were significantly decreased in the …
Effects Of Contemporary Orthodontic Composites On Tooth Color Following Short-Term Fixed Orthodontic Treatment: A Controlled Clinical Study, Bayram Çörekçi̇, Ebubeki̇r Toy, Firat Öztürk, Siddik Malkoç, Bora Öztürk
Effects Of Contemporary Orthodontic Composites On Tooth Color Following Short-Term Fixed Orthodontic Treatment: A Controlled Clinical Study, Bayram Çörekçi̇, Ebubeki̇r Toy, Firat Öztürk, Siddik Malkoç, Bora Öztürk
Turkish Journal of Medical Sciences
Background/aim: To determine the color alterations of natural teeth associated with different orthodontic composites used in comprehensive short-term treatment. Materials and methods: Twenty-two patients were treated with ?xed appliances and 22 untreated subjects were also evaluated. Lower incisors were bonded with different orthodontic composites: 42 with Grengloo, 41 with Light Bond, 31 with Kurasper F, and 32 with Transbond XT. The color parameters of the Commission Internationale de l'Eclairage (CIE) were measured for each tooth with a spectrophotometer. Color assessment in relation to time, adhesive material, and their interaction was made with 2-way mixed analysis of variance (ANOVA) and 1-way …
Bioimpedance For Assessing Volume Status In Children With Nephrotic Syndrome, Kadri̇ye Özdemi̇r, Makbule Sevgi̇ Mi̇r, Ni̇da Di̇nçel, Si̇bel Bozabali, İpek Kaplan Bulut, Ebru Yilmaz, Betül Sözeri̇
Bioimpedance For Assessing Volume Status In Children With Nephrotic Syndrome, Kadri̇ye Özdemi̇r, Makbule Sevgi̇ Mi̇r, Ni̇da Di̇nçel, Si̇bel Bozabali, İpek Kaplan Bulut, Ebru Yilmaz, Betül Sözeri̇
Turkish Journal of Medical Sciences
Background/aim: The effectiveness of assessing volume load via bioimpedance in pediatric patients with nephrotic syndrome (NS) was investigated. Materials and methods: Patients with NS (n = 34) were compared with healthy controls (n = 20). The inferior vena cava index and inferior vena cava collapsibility index (IVCCI) scores were determined for all subjects. Bioimpedance measurements were used to directly determine volume load. Clinical findings, relative fluid load, and echocardiographic measurements were determined and compared with bioimpedance in calculating volume load. Results: The sensitivity and specificity of bioimpedance in determining volume load were found to be 65% and 90%, respectively. IVCCI …
Opinions Of The Turkish Population On Cancer And Being Informed Of The Diagnosis Of Cancer, Abdussamed Yalçin, Kami̇le Silay, Abdullah Büyükçeli̇k, Abdurrahman Işikdoğan, Haci Mehmet Türk, Hasan Şenol Coşkun, Feyyaz Özdemi̇r, Mehmet Uğurlu, Yusuf Üstü, Bülent Yalçin
Opinions Of The Turkish Population On Cancer And Being Informed Of The Diagnosis Of Cancer, Abdussamed Yalçin, Kami̇le Silay, Abdullah Büyükçeli̇k, Abdurrahman Işikdoğan, Haci Mehmet Türk, Hasan Şenol Coşkun, Feyyaz Özdemi̇r, Mehmet Uğurlu, Yusuf Üstü, Bülent Yalçin
Turkish Journal of Medical Sciences
Background/aim: An opinion survey was conducted to investigate the opinions and attitudes of the Turkish population regarding cancer if they or one of their family members were to receive a diagnosis of cancer. Materials and methods: The opinion survey was completed by 6566 subjects and consisted of questions about the demographics of the participants and their overall opinions about cancer. The other points of the investigation asked whether they would inform relatives who had cancer about the diagnosis and whether they would prefer to be informed if they were the one with the cancer diagnosis. Results: The median age of …
What Primary Care Physicians Think About Insulin Initiation In Type 2 Diabetes:A Field-Based Study, Muharrem Ak, Mustafa Haki̇ Sucakli, Meti̇n Canbal, Yaşar Koşar
What Primary Care Physicians Think About Insulin Initiation In Type 2 Diabetes:A Field-Based Study, Muharrem Ak, Mustafa Haki̇ Sucakli, Meti̇n Canbal, Yaşar Koşar
Turkish Journal of Medical Sciences
Background/aim: A significant number of patients with type 2 diabetes mellitus require insulin and little is known about the possible physician-related factors that could cause a delay in the initiation of insulin treatment in patients with type 2 diabetes. This study aimed to evaluate those factors. Materials and methods: A total of 87 family physicians working at 36 family health centers in urban Malatya participated in our study on a voluntary basis. A self-administered survey form was structured to gather the views of the primary care physicians. The survey was developed based on a review of the literature. The survey …
What Is The Main Target: A Clearer Colon With A Sennoside-Based Regime, Or Adequate Bowel Cleansing Before Colonoscopy With A Peg-El-Based Regime?, Aki̇f Altinbaş, Bariş Yilmaz, Bora Aktaş, Fuat Eki̇z, Zahi̇de Şi̇mşek, Ömer Başar, Şahi̇n Çoban, Osman Yüksel
What Is The Main Target: A Clearer Colon With A Sennoside-Based Regime, Or Adequate Bowel Cleansing Before Colonoscopy With A Peg-El-Based Regime?, Aki̇f Altinbaş, Bariş Yilmaz, Bora Aktaş, Fuat Eki̇z, Zahi̇de Şi̇mşek, Ömer Başar, Şahi̇n Çoban, Osman Yüksel
Turkish Journal of Medical Sciences
Background/aim: Even though polyethylene glycol-electrolyte lavage (PEG-EL)-based regimes have become the gold standard in recent years, to finish drinking 4 L of PEG-EL solution can be difficult. The quality of sennoside-based bowel-cleansing regimes used in Turkey has been known for some time. Therefore, we aimed to investigate the efficacy of both bowel-cleansing regimes. Materials and methods: Patients over 18 years old undergoing elective colonoscopic procedures between January and March 2011 were included in the study. The patients were divided into 2 groups; in Group 1, 91 patients were given sennoside a + b calcium 500 mg/250 mL (X-M solution, Yenişehir …
Surgical Management Of Pulmonary Aspergilloma: Clinical Experience With 77 Cases, Koray Aydoğdu, Funda İncekara, Mehmet Furkan Şahi̇n, Seli̇m Şaki̇r Erkmen Gülhan, Göktürk Findik, Abdullah İrfan Taştepe, Sadi̇ Kaya
Surgical Management Of Pulmonary Aspergilloma: Clinical Experience With 77 Cases, Koray Aydoğdu, Funda İncekara, Mehmet Furkan Şahi̇n, Seli̇m Şaki̇r Erkmen Gülhan, Göktürk Findik, Abdullah İrfan Taştepe, Sadi̇ Kaya
Turkish Journal of Medical Sciences
Background/aim: This retrospective study evaluated the clinical presentation, underlying lung disease, surgical indications, technique, treatment outcomes, and postoperative complications of pulmonary aspergilloma. Materials and methods: We evaluated 77 patients who underwent pulmonary resection of an aspergilloma at Atatürk Chest Diseases and Thoracic Surgery Research and Training Hospital between January 2000 and December 2013. The initial operations were 4 pneumonectomies, 24 lobectomies, 9 lobectomy plus myoplasties, 10 segmental resections, and 30 wedge resections. Six reoperations were carried out to deal with postoperative complications: 1 myoplasty, 2 completion lobectomies plus myoplasties, 2 myoplasties with rib resections, and 1 completion lobectomy. Results: The …
Effectiveness Of Pelvic Floor Muscle Training On Symptoms And Uroflowmetryparameters In Female Patients With Overactive Bladder, Haluk Kulaksizoğlu, Murat Akand, Evri̇m Çakmakçi, Murat Gül, Bedreddi̇n Seçki̇n
Effectiveness Of Pelvic Floor Muscle Training On Symptoms And Uroflowmetryparameters In Female Patients With Overactive Bladder, Haluk Kulaksizoğlu, Murat Akand, Evri̇m Çakmakçi, Murat Gül, Bedreddi̇n Seçki̇n
Turkish Journal of Medical Sciences
Background/aim: To evaluate the effects of pelvic floor muscle training (PFMT) on symptoms of overactive bladder (OAB) as well as uroflowmetry parameters and functional bladder capacity. Materials and methods: Fifty-nine female patients with OAB symptoms were included. Patients were assessed by SEAPI-QMM, uroflowmetry, and abdominal ultrasound. A specially designed PFMT program using a Pilates ball was generated for patients. The training period was 1-h sessions twice a week for 6 weeks and aerobic home exercises to be performed at home 4 or 5 times every other day. Following training, subjects were reevaluated for body mass index, SEAPI questionnaire, and uroflowmetry. …
The Role Of Radiotherapy After Radical Prostatectomy, Meryem Aktan, Mehmet Koç
The Role Of Radiotherapy After Radical Prostatectomy, Meryem Aktan, Mehmet Koç
Turkish Journal of Medical Sciences
No abstract provided.
Effects Of Prenatally Exposed Diclofenac Sodium On Rat Heart Tissue:A Stereological And Histological Study, Fi̇kret Gevrek, Mi̇kai̇l Kara, Murat Çeti̇n Rağbetli̇, Hüseyi̇n Aslan
Effects Of Prenatally Exposed Diclofenac Sodium On Rat Heart Tissue:A Stereological And Histological Study, Fi̇kret Gevrek, Mi̇kai̇l Kara, Murat Çeti̇n Rağbetli̇, Hüseyi̇n Aslan
Turkish Journal of Medical Sciences
Background/aim: Diclofenac sodium (DS) can cross the placental barrier and affect the fetus, and its consumption during pregnancy may cause developmental malformation of embryos. This study investigates the effect of prenatally applied DS on the quantitative morphology of the adult rat heart. Materials and methods: Pregnant rats were divided into three groups (control, sham, and test). The rats in the test group were injected with DS; the control group received physiological saline (1 mL; 1 mg/kg, i.m.) from the 5th to the 20th day of pregnancy; and the rats in the sham group were not injected at all. At the …
Does Glp-2 Have A Protective Effect On Cerebral Ischemia/Reperfusion Model?, Naci̇ Topaloğlu, Gülsün Memi̇, Tuncay Kaner, Mustafa Deni̇z, Önder Şahi̇n, Mustafa Güven, Murat Çoşar
Does Glp-2 Have A Protective Effect On Cerebral Ischemia/Reperfusion Model?, Naci̇ Topaloğlu, Gülsün Memi̇, Tuncay Kaner, Mustafa Deni̇z, Önder Şahi̇n, Mustafa Güven, Murat Çoşar
Turkish Journal of Medical Sciences
Background/aim: To investigate the neuroprotective effects of glucagon-like peptide 2 (Glp-2), which increases cerebral blood flow, on the hippocampal complex after cerebral ischemia/reperfusion (I/R) injury in rats. Materials and methods: Animals were randomized into 4 groups: sham, I/R + 0.9% NaCl, I/R + pre-Glp-2, and I/R + post-Glp-2. Cerebral ischemia was performed via the occlusion of the bilateral internal carotid artery for 40 min and continued with a reperfusion process. At the end of 6 h of reperfusion, animals were decapitated in all groups and brain tissues were removed. Malondialdehyde (MDA) and natural intracellular antioxidant glutathione (GSH) levels and myeloperoxidase …
Prevention Of Methotrexate-Induced Nephrotoxicity By Concomitantadministration Of Garlic Aqueous Extract In Rat, Walaa Ahmed, Amr Zaki, Taghred Nabil
Prevention Of Methotrexate-Induced Nephrotoxicity By Concomitantadministration Of Garlic Aqueous Extract In Rat, Walaa Ahmed, Amr Zaki, Taghred Nabil
Turkish Journal of Medical Sciences
Background/aim: Methotrexate (MTX) has been widely used for treatment of cancer and rheumatoid arthritis, but its use has been limited by its nephrotoxicity. This study was carried out to determine whether garlic exerts a protective effect against MTX-induced nephrotoxicity. Materials and methods: Nephrotoxicity was induced in rats after a single i.p. injection of MTX (20 mg/kg). Garlic extract (1 mL/100 g b.w.) was given orally for 7 days before and after MTX administration. Serum samples were collected to evaluate urea, creatinine, sodium, phosphorous, potassium, and calcium. Reduced glutathione, catalase, adenosine deaminase, nitric oxide, and malondialdehyde were measured in renal tissue. …