Medicine and Health Sciences Commons^™

Clinical Observation Of Glp-1ra And Substance Use (Cogs) Study Preliminary Data Outcomes, Akshara S. Narahari, Nzingha Johnson

Summer Research Program Abstracts

No abstract provided.

Neuroinflammatory Profiles In The Hippocampus Of Cognitively Resilient Alzheimer's Disease Patients, William H. Otte, Avery Matthews, Hongyu Wu, Ashlee Arizmendez, Michael E. Maniskas, Xinhai (Robert) Zhang, Chunfeng (Sheryl) Tan

Summer Research Program Abstracts

No abstract provided.

Understanding Delays In Human Milk Fortification Timing And Impact On Growth Outcomes In Very Low Birthweight Preterm Infants, Maria Poblete, Sepideh Saroukhani, Manouchehr Hessabi Md, Mph, Amirali Tahanan Ms, Lindsay F Holzapfel

Summer Research Program Abstracts

No abstract provided.

Ai-Segmented Upper Airway Imaging Biomarkers Across The Lifespan, David L. Holt, Vishwa S. Parekh

Summer Research Program Abstracts

No abstract provided.

Implementation Study Of Aortagpt, An Ai Decision Support Tool For Heritable Thoracic Aortic Disease, Noah Mathai

Summer Research Program Abstracts

No abstract provided.

The Role Of The Hs1582 Enhancer In The Regulation Of Spry1 In Human Neural Crest Cells, Maia Williams, Vershanna E Morris

Summer Research Program Abstracts

No abstract provided.

Clinical Characterization Of Non-Severe Retinal Hemorrhages In Pediatric Patients: A Retrospective Case Series, Scott Koh, Marybeth Farazdaghi, Ashley Gibson, Van Michelle Ruda

Summer Research Program Abstracts

No abstract provided.

Microrna Regulation Of Human Trophoblast Stem Cell Proliferation, Eva E. Adams, Madison Vu, Jacqueline G. Parchem

Summer Research Program Abstracts

No abstract provided.

Population-Level Eligibility For Bonemri As A Radiation-Free Alternative To Spine Ct, Niels Levy-Thiebaut, Timothy Borden Md

Summer Research Program Abstracts

No abstract provided.

Effect Of Pparα Inhibition On Metabolic Maturation In Primary Murine Cardiomyocytes, Aedan Christian S. Villegas, Brenna Servantes, Ximena Medina Romero, Jacqueline Parchem, Tina Oak Findley

Summer Research Program Abstracts

No abstract provided.

Comparison Of Refractive Accuracy Of Iolmaster 700, Lenstar Ls 900, And Anterion For Iol Power Calculation, Travis Williams Md Ms, Mena Kozman Md, Siddhant Patil, Leon Toursarkissian, Ahmad Kheirkhah Md

Summer Research Program Abstracts

No abstract provided.

Reducing Over-Isolation: Baseline Evaluation Of Isolation Precaution Reassessment In Hospitalized Children, Laura Brambilla, Wan-Hsuan Chen

Summer Research Program Abstracts

No abstract provided.

Procedural Pain In Extremely Preterm Infants During The First 28 Days Of Life, Emma Young, Manouchehr Hessabi Md, Amirali Tahanan Ms, Sepideh Saroukhani Md, Phd, Amanda Zander Msn, Rn, Christine Domonoske Pharmd, Matthew Martin-Souza Pharmd, Amir Khan Md, Allison Davidson Md, Jaclyn Ruggiero Md

Summer Research Program Abstracts

No abstract provided.

Del Nido Versus Blood Cardioplegia In Pediatric Congenital Heart Surgery: A Systematic Review And Meta-Analysis, Sahej Bhogal

Summer Research Program Abstracts

No abstract provided.

Characteristics In Patients With Adolescent Idiopathic Scoliosis Undergoing Bracing That Impact Corrected Spinal Curves, James A. Flegle

Summer Research Program Abstracts

No abstract provided.

The Effect Of Vaccine Mandates On Disease Spread: Evidence From College Covid-19 Mandates, Riley K. Acton, Wenjia Cao, Emily E. Cook, Scott A. Imberman, Michael F. Lovenheim

Research Collection School Of Economics

Nearly 700 4-year U.S. colleges mandated students receive COVID-19 vaccinations in fall 2021. Using data on college policies and county health, we estimate how mandates affect surrounding communities. Event studies from August to November 2021 show that mandates covering all colleges in a county reduced COVID-19 deaths by 5.6 per 100,000 persons, a 4.6% reduction in the U.S. total during this period. Mandates reduced COVID cases by 504 and ICU admissions by 16.2 per 100,000, though we see no statistically significant impact on hospitalizations. Impacts are larger in counties with larger college populations and low estimated ex-ante student vaccination rates.

Staff Education To Improve Lithium Adherence In Bipolar I Disorder Through Staff Education, Queendroline Fundong Nkeh

Walden Dissertations and Doctoral Studies

No abstract provided.

Transoral Endoscopic Stapled Diverticulotomy For Pediatric Esophageal Diverticulum: A Case Report, Nadeen Alturki, Huma Quraishi, Keith A. Kuenzler

Manuscripts, Articles, Book Chapters and Other Papers

Introduction

Case presentation

Factors Associated With Pre-Donation Health-Related Quality-Of-Life Among Pediatric Sibling Hematopoietic Cell Donors: A Donorkids Ql Study., Galen E. Switzer, Jessica G. Bruce, Bronwen E. Shaw, Vidya Kuniyil, James W. Varni, Brandan J. Butler, Connor Erickson, Alisha Mussetter, Allison Neutzling, Hisham Abdel-Azim, Paibel Aguayo-Hiraldo, Eric J. Anderson, Victor M. Aquino, Karlie Boone, Farid Boulad, Joseph H. Chewning, Jessica Cooper, Ann Dahlberg, Christopher C. Dvorak, Jorge Galvez-Silva, Ann E. Haight, Jennifer A. Hoag, Michelle Hudspeth, David Jacobsohn, Kimberly A. Kasow, Carrie L. Kitko, Lakshmanan Krishnamurti, Lisa Madden, Holly K. Miller, Erin Morales, Timothy S. Olson, Anna B. Pawlowska, Vinod K. Prasad, Troy C. Quigg, Andromachi Scaradavou, Niketa C. Shah, Shalini Shenoy, Nancy Terwilliger, Lori Wiener, Gregory A. Yanik, Lolie C. Yu, Michael A. Pulsipher

Manuscripts, Articles, Book Chapters and Other Papers

Due to limited published data assessing pediatric hematopoietic cell donor experiences, we previously conducted one of the largest quantitative investigations of pediatric donor experiences and health-related quality-of-life (HRQoL) at the time (RDSafe). Findings from RDSafe demonstrated that a subset of pediatric HC donors experienced very poor HRQoL; unfortunately, that dataset addressed only a limited number of factors, and key associations explaining this poor HRQoL were not found. In this study, our goal was to address that deficit by describing pre-donation donor HRQoL in detail and identifying factors across five key domains that were associated with donor HRQoL. We conducted a …

Quality Improvement Project To Reduce Wait Time For Pediatric Gastrointestinal Procedures., Jennifer Colombo, Nicholas Clark, Laura E. Shroyer, Dustin J. Hahn, Jonathan Patterson, Kenneth Sam

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Delays in care can lead to poor health outcomes and suboptimal patient and family experiences. We aimed to reduce the average wait time for gastrointestinal endoscopic procedures (procedure request to procedure completion) from 145 to 15 days (a 90% reduction) within 4 months (November 2023 to March 2024).

METHODS: A3 problem-solving methodology was used. The primary intervention was a multiday, multidisciplinary improvement workshop. Outcome measures included (1) procedure request date to procedure completion date, and (2) favorable patient satisfaction score for timeliness of access to care. Process measures included (1) procedure request date to date procedure scheduled by staff, …

Immediate Postoperative Pacing Dependency Is Not Associated With Worse Mid-Term Survival In Redo Mitral Valve Surgery, Devon Kelley, Joyce Ho, Andrew Belec, Takahiro Tashima, Victoria Li, James Lao, Varun Kathawate, Kazuhiro Ueno, Amit Iyengar, Jessica Dominic, Pavan Atluri

Division of Cardiology Faculty Papers

Risk factors (RF) for permanent pacemaker (PPM) placement in cardiac surgery include valvular operations and redo operations. We aim to identify RF for PPM placement prior to discharge (DC) specifically among redo mitral valvular operations, and to analyze outcomes in this population. Our retrospective review considered 943 patients undergoing redo MV operations between 01/2002 and 12/2021, excluding patients experiencing in-hospital death within 48 hours of their operation and patients with existing PPM or implanted cardiac defibrillator (ICD). Patients (n = 742) were categorized based on whether they received a PPM before DC or not. Of the 742 patients analyzed, 47 …

In Vivo Evidence Of Blood Flow Slippage: Failure Of The No-Slip Boundary Condition Assumption, Alena Jarolímová, Jaroslav Hron, Karel Tůma, Radomír Chabiniok, Josef Málek, Keshava Rajagopal

Division of Cardiology Faculty Papers

The assumption that blood adheres to vessel walls with zero tangential velocity component, the so-called "no-slip" boundary condition, is a foundational premise of cardiovascular fluid dynamics. Whether the no-slip condition holds in vivo, however, remains unknown. Seven healthy adult volunteers underwent cardiovascular magnetic resonance imaging. With four-dimensional flow magnetic resonance imaging of the descending thoracic aorta and modeling blood as a Navier-Stokes fluid, near-wall blood velocities were quantified, and wall shear stress was calculated based on the measured velocity fields. Within the Navier-Stokes data assimilation framework, tangential wall velocities of ∼30-80% of the mean luminal velocity were consistently obtained. These …

Neoadjuvant Immunotherapy For Hepatocellular Carcinoma Is Associated With Improved Survival After Hepatectomy: A Matched Analysis Of The 2017 To 2022 National Cancer Database, Lawrence Chiang, Adam Bodzin, Daniel Lin, Nader Hanna, Scott Koeneman, Hien Dang, Charles J. Yeo, Christopher Shubert, R. Zheng

Department of Surgery Faculty Papers

Background: Effects of neoadjuvant immunotherapy (NIT) before liver resection are not well-described in hepatocellular carcinoma (HCC). Survival and R0 resection rates in HCC patients undergoing curative-intent resection with or without NIT were evaluated.

Methods: A retrospective study of stage I-III HCC patients undergoing hepatectomy from the 2017–2022 National Cancer Database was performed. Patients receiving NIT were exactly matched 1:3 to non-NIT patients by clinical stage. Primary outcomes were margin positivity, 30- and 90-day mortality, and overall survival.

Results: After matching 510 patients, 97 received NIT and 291 did not (non-NIT). Resections included segmental (178, 45.9%), lobar (149, 38.4%), and extended …

Comparing Intraosseous (Io) Access To Intravenous (Iv) Access, Isabella Ouellette Rn, Charlyn Achola Rn, Catherine Marcoullier Rn

Nurse Residency

In adult patients experiencing cardiac arrest, how does intraosseous access compared to intravenous access affect time to medication administration and return of spontaneous circulation (ROSC) during resuscitation?

Patient Ratio Impact On Patient Safety In The Emergency Department, Erin Griffin Rn, Rhonda Leavitt Rn

Nurse Residency

How does high patient to nurse ratios effect patient outcome and satisfaction compared to lower nurse to patient ratios?

Implementation Of Acute Pain Management Protocols And Effect On Rescue Opioid Administration During Ed Stay, Victoria Nordbeck Rn, Avegail Avila Rn, Sarah Durocher Rn, Isabel Dimek Rn

Nurse Residency

In patients presenting with acute pain processes in the emergency department, how does the implementation of acute pain protocols compared to standard opioid based therapies affect needs for rescue medication and overall length of stay?

Behavioral Risks, Sophie Coro Rn, Katelyn Piche Rn, Maria Neihauser Rn, Mia Martel Rn

Nurse Residency

In nurses caring for behavioral risk patients, does the use of electronic behavioral alert systems compared to no alert systems reduce nurse-patient workplace violence?

Does Apply Boarder Foam Dressings Decrease Hapi In High-Risk Patients In The Acute Care Setting, Felicia Burton Rn, Kathryn Twombly Rn, Amanda Ring Rn

Nurse Residency

Does applying border foam dressings (i.e.mepilex dressings) to patients at risk for skin breakdown prevent pressure injuries and skin breakdown during a patient's hospital stay?

Standardization Of Objectives And Response Criteria For Neoadjuvant Immunotherapy In Resectable Squamous Cell Carcinoma Of The Head And Neck, Carlo Resteghini, Athanassios Argiris, Pierre Blanchard, Irene Braña, Anna Maria Camarda, Anthony T. C. Chan, Robert Ferris, Vincent Gregoire, Kevin J. Harrington, Ingeborg Tinhofer, Senada Koljenović, Nancy Y. Lee, C. René Leemans, Jean-Pascal Machiels, Hisham Mehanna, Robert Metcalf, Brian O'Sullivan, Sjoukje Oosting, Ester Orlandi, Vinidh Paleri, Amanda Psyrri, Nabil F F. Saba, Sandra Schmitz, Christian Simon, Makoto Tahara, Vincent Vander Poorten, Milan Vošmik, Paolo Bossi

Department of Medical Oncology Faculty Papers

The management of locally-advanced, resectable head and neck squamous cell carcinoma (HNSCC) is undergoing a major shift driven by the integration of neoadjuvant immunotherapy (nIO). The rationale for nIO lies in its administration within an immunologically active, treatment-naïve microenvironment that enhances immune priming and anti-tumor response. Despite encouraging clinical data, including the pivotal KEYNOTE-689 trial and multiple phase II studies, methodological heterogeneity in trial design, endpoint definitions, and response criteria currently hampers data comparability and the establishment of new standards of care. This expert narrative review proposes a structured framework for standardizing clinical, pathologic, imaging, and translational endpoints in HNSCC …

Health Beliefs And Lung Cancer Screening Uptake Among Eligible Asian Americans In Philadelphia, Pennsylvania, United States, Julia G. Katcher, Kuang-Yi Wen, Christine S. Shusted, Jessica Liang, Kyunghee Koh, Hee-Soon Juon, Julie Barta

Department of Medical Oncology Faculty Papers

OBJECTIVE: Asian Americans experience disproportionately late-stage lung cancer diagnoses and lower lung cancer screening (LCS) rates than other racial groups. This study evaluated the association between the

METHODS: This pilot randomized controlled trial, conducted April 2023-January 2024 within a Philadelphia health system, tested a culturally and linguistically tailored intervention led by community health workers. LCS completion and LCS-Health Belief Scale (LCS-HBS) responses were compared between control and intervention participants (

RESULTS: LCS completion was higher in the intervention group (45%) than in the control (31.3%). Control participants who completed LCS reported higher perceived lung cancer risk, greater perceived benefits, and …