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Articles 3301 - 3330 of 8080
Full-Text Articles in Medicine and Health Sciences
Removing The Specimen With Traction During Robotic Radical Prostatectomy Does Not Cause A Positive Surgical Margin, Serkan Altinova, Abi̇di̇n Egemen İşgören, Zi̇ya Akbulut, Muhammet Fuat Özcan, Abdullah Erdem Canda, Ali̇ Fuat Atmaca, Mevlana Derya Balbay
Removing The Specimen With Traction During Robotic Radical Prostatectomy Does Not Cause A Positive Surgical Margin, Serkan Altinova, Abi̇di̇n Egemen İşgören, Zi̇ya Akbulut, Muhammet Fuat Özcan, Abdullah Erdem Canda, Ali̇ Fuat Atmaca, Mevlana Derya Balbay
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to gauge whether removal of a specimen with traction during robot-assisted laparoscopic radical prostatectomy causes a positive surgical margin or not. Materials and methods: One hundred and sixty-nine patients with localized prostate cancer who underwent robot-assisted laparoscopic radical prostatectomy from 2009 to 2011 were included in the study. After dividing the patients into two groups, we recorded their characteristics and pre-op/post-op evaluations. Results: There were 111 and 58 patients in groups 1 (with traction) and 2 (without traction), respectively. We evaluated the patients' ages, follow-up time, body mass index (BMI), prostate-specific antigen (PSA) …
Clinical Correlation Between The 6-Min Walk Test Andcardiopulmonary Exercise Testing In Patients With Pulmonary Arterial Hypertension, Serap Acar, Sema Savci, Di̇dem Karadi̇bak, Buse Özcan Kahraman, Bahri̇ Akdeni̇z, Ebru Özpeli̇t, Can Sevi̇nç
Clinical Correlation Between The 6-Min Walk Test Andcardiopulmonary Exercise Testing In Patients With Pulmonary Arterial Hypertension, Serap Acar, Sema Savci, Di̇dem Karadi̇bak, Buse Özcan Kahraman, Bahri̇ Akdeni̇z, Ebru Özpeli̇t, Can Sevi̇nç
Turkish Journal of Medical Sciences
Background/aim: The aims of the present study were to assess the relationship between the distance walked during the 6-min walk test (6MWT) and exercise capacity as determined by cardiopulmonary exercise testing (CPET) in patients with pulmonary arterial hypertension (PAH) and to investigate the prognostic value of the 6MWT in comparison to clinical parameters of CPET and echocardiography findings. Materials and methods: Thirty PAH patients participated in the study. Subject characteristics and New York Heart Association (NYHA) classifications were recorded. All subjects completed the 6MWT and CPET. Relationships among the variables were analyzed by the Pearson correlation test. Correlation coefficients between …
Applying The International Classification Of Functioning, Disability, And Health In Children With Low Vision: Differences Between Raters, Feri̇de Yarar, Uğur Cavlak, Bi̇lge Başakci Çalik
Applying The International Classification Of Functioning, Disability, And Health In Children With Low Vision: Differences Between Raters, Feri̇de Yarar, Uğur Cavlak, Bi̇lge Başakci Çalik
Turkish Journal of Medical Sciences
Background/aim: This study was conducted to analyze the agreement between International Classification of Functioning, Disability, and Health (ICF) raters and to show its applicability in children with low vision. Materials and methods: Twenty children (mean age: 11.70 ± 1.92 years) were included. To evaluate the independency of the sample, the Northwick Park Activities Daily Living questionnaire was used. The Low Vision Quality of Life Scale was used to evaluate quality of life. An ICF core set was developed to be used in this study. The core set consisted of 13 items for body functions, 3 items for body structures, 36 …
Cryptogenic Organizing Pneumonia: Clinical And Radiological Features, Treatment Outcomes Of 17 Patients, And Review Of The Literature, Eli̇f Yelda Ni̇ksarlioğlu, Gülci̇han Zehra Özkan, Nur Di̇lek Bakan, Si̇bel Yurt, Lütfi̇ye Kiliç, Güngör Çamsari
Cryptogenic Organizing Pneumonia: Clinical And Radiological Features, Treatment Outcomes Of 17 Patients, And Review Of The Literature, Eli̇f Yelda Ni̇ksarlioğlu, Gülci̇han Zehra Özkan, Nur Di̇lek Bakan, Si̇bel Yurt, Lütfi̇ye Kiliç, Güngör Çamsari
Turkish Journal of Medical Sciences
Background/aim: We evaluated patients with cryptogenic organizing pneumonia (COP) who attended our clinic. Materials and methods: We retrospectively investigated the clinical and radiological findings, diagnostic methods, treatment, and follow-up outcomes of 17 patients who had been histopathologically diagnosed with COP. Results: The mean age of the patients was 49.8 ± 10.4 years. The most common symptom was cough (n = 15; 88.2%) and the most common radiological finding (n = 10) was consolidation in the inferior lobes on thoracic computed tomography. The diagnosis of COP was made by open lung biopsy in 11 (64.7%) patients, transbronchial biopsy in 5 (29.4%), …
Experiential Avoidance, Empathy, And Anger-Related Attitudesin Antisocial Personality Disorder, Kaasim Fati̇h Yavuz, Oktay Şahi̇n, Sevi̇nç Ulusoy, Okan Ufuk İpek, Erhan Kurt
Experiential Avoidance, Empathy, And Anger-Related Attitudesin Antisocial Personality Disorder, Kaasim Fati̇h Yavuz, Oktay Şahi̇n, Sevi̇nç Ulusoy, Okan Ufuk İpek, Erhan Kurt
Turkish Journal of Medical Sciences
Background/aim: In prevailing opinion, a strong relation exists between lack of empathy and antisocial personality disorder (ASPD). However, recent data fail to wholly clarify this relation, especially in consideration of empathy dimensions. In this study our aim was to address ASPD and social functionality from a contextual behavioral science viewpoint. Materials and methods: The present study was conducted with a sample of 34 individuals with ASPD and 32 healthy individuals as the control group. The participants were assessed with a sociodemographic form, Structured Clinical Interviews for DSM I and II (SCID-I and SCID-II), Social Functioning Scale (SFS), Acceptance and Action …
The Combined Effects Of Proteasome Inhibitor Bortezomib With Topoisomerase I And Ii Inhibitors On Topoisomerase Enzymes, Emi̇ne Öksüzoğlu, Çi̇ydem Tirinoğlu, Bariş Keri̇moğlu
The Combined Effects Of Proteasome Inhibitor Bortezomib With Topoisomerase I And Ii Inhibitors On Topoisomerase Enzymes, Emi̇ne Öksüzoğlu, Çi̇ydem Tirinoğlu, Bariş Keri̇moğlu
Turkish Journal of Medical Sciences
Background/aim: DNA topoisomerases are ubiquitous enzymes that regulate conformational changes in DNA topology during essential cellular processes, and, for this reason, have been characterized as the cellular targets of a number of anticancer drugs. Bortezomib is a powerful proteasome inhibitor used in the treatment of hematological malignancies. In this study, we investigated the inhibitory effects of bortezomib on human topoisomerase I and II enzymes both alone and in combination modes with camptothecin and etoposide. Materials and methods: The interactions of these drugs with topoisomerase enzymes were evaluated by relaxation assay in cell-free systems. IC50 values of the drugs on topoisomerase …
Neuroprotective Effects Of Bone Marrow-Derived Mesenchymal Stem Cellsand Conditioned Medium In Mechanically Injured Neuroblastoma Cells, Mesut Mete, Işil Aydemi̇r, Ülkü Ünlü Ünsal, Yusuf Kurtuluş Duransoy, Mehmet İbrahi̇m Tuğlu, Mehmet Selçuki̇
Neuroprotective Effects Of Bone Marrow-Derived Mesenchymal Stem Cellsand Conditioned Medium In Mechanically Injured Neuroblastoma Cells, Mesut Mete, Işil Aydemi̇r, Ülkü Ünlü Ünsal, Yusuf Kurtuluş Duransoy, Mehmet İbrahi̇m Tuğlu, Mehmet Selçuki̇
Turkish Journal of Medical Sciences
Background/aim: Bone marrow-derived mesenchymal stem cells (BMSCs) possess self-renewal characteristics that distinguish them from other cell types. Recent studies have focused on the effects of conditioned medium (CM) that includes the extracellular matrix. Here we examined the neuroprotective effects of BMSCs and CM on damaged neuroblastoma cells. Materials and methods: The cells were divided into five groups: 1) healthy controls, 2) damaged cells alone, 3) damaged cells treated with BMSCs, 4) damaged cells treated with CM, and 5) damaged cells treated with both BMSCs and CM. Neuroprotective effects were then evaluated based upon the levels of oxidative stress, antitransforming growth …
Virulence Factors, Biofilm-Forming Ability, And Antimicrobial Resistance Of Urinary Escherichia Coli Strains Isolated From Hospitalized Patients, Barbara Kot, Jolanta Wicha, Agata Gruzewska, Malgorzata Piechota, Katarzyna Wolska, Maria Obrebska
Virulence Factors, Biofilm-Forming Ability, And Antimicrobial Resistance Of Urinary Escherichia Coli Strains Isolated From Hospitalized Patients, Barbara Kot, Jolanta Wicha, Agata Gruzewska, Malgorzata Piechota, Katarzyna Wolska, Maria Obrebska
Turkish Journal of Medical Sciences
Background/aim: Escherichia coli is the most frequent cause of urinary tract infections. We investigated the possible associations between the origin of strains, antimicrobial resistance, the presence of urovirulence factors, and biofilm-forming ability. Materials and methods: Antibiotic susceptibility of E. coli strains was tested by disk diffusion method. Hemagglutination assays were performed for phenotypic characterization of the cell surface. Multiplex PCR was used for detection of virulence genes and for determination of phylogenetic relationships. Results: The resistance to ampicillin (55.5%) and tetracycline (39.3%) was significantly more frequent than to other antimicrobial agents. The fim gene was present in 92.5% of strains. …
Distribution Of Hepatitis C Virus Genotypes Among Intravenous Drug Users In The Çukurova Region Of Turkey, Enver Üçbi̇lek, Bahri̇ Abayli, Mahmut Bakir Koyuncu, Durdane Midikli, Süveyda Gözüküçük, Alper Akdağ, Osman Özdoğan, Engi̇n Altintaş, Orhan Sezgi̇n
Distribution Of Hepatitis C Virus Genotypes Among Intravenous Drug Users In The Çukurova Region Of Turkey, Enver Üçbi̇lek, Bahri̇ Abayli, Mahmut Bakir Koyuncu, Durdane Midikli, Süveyda Gözüküçük, Alper Akdağ, Osman Özdoğan, Engi̇n Altintaş, Orhan Sezgi̇n
Turkish Journal of Medical Sciences
Background/aim: The most common hepatitis C virus (HCV) genotype in Turkey is genotype 1. However, there has not been a study about the distribution of HCV genotypes among intravenous drug users (IVDUs) in the Çukurova region of Turkey. This study was planned to understand if there is a difference between IVDUs and the normal population. Materials and methods: Between May 2010 and May 2014, anti-HCV positive IVDUs who applied to the 6 hospitals in the Çukurova region of Turkey were included in this study. Their HCV genotypes were studied. Results: Ninety-seven anti-HCV positive IVDUs were screened in terms of HCV …
Diagnostic Accuracy Of Noninvasive End-Tidal Carbon Dioxide Measurement In Emergency Department Patients With Suspected Pulmonary Embolism, Meli̇h Yüksel, Murat Pekdemi̇r, Serkan Yilmaz, Eli̇f Yaka, Asli Gülfer Kartal
Diagnostic Accuracy Of Noninvasive End-Tidal Carbon Dioxide Measurement In Emergency Department Patients With Suspected Pulmonary Embolism, Meli̇h Yüksel, Murat Pekdemi̇r, Serkan Yilmaz, Eli̇f Yaka, Asli Gülfer Kartal
Turkish Journal of Medical Sciences
Background/aim: Pulmonary embolism (PE) is a frequent health problem representing a diagnostic challenge with high mortality and morbidity rates. The aim of this study was to investigate the value of end-tidal carbon dioxide (ETCO2) and alveolar dead space fraction (ADSF) in the diagnosis of PE. Materials and methods: ETCO2 levels of patients with suspected PE were measured with a noninvasive mainstream sensor. ADSF of patients was calculated and PaCO2 levels were also obtained. ROC curve analysis was used to determine diagnostic values of ETCO2 and ADSF for PE. Results: The study included 159 patients. The mean values for ETCO2 and …
Tracheal Intubation In Patients Immobilized By A Rigid Collar: A Comparison Of Glidescope And An Intubating Laryngeal Mask Airway, Semi̇h Özdi̇l, Zehra İpek Arslan Aydin, Zehra Nur Baykara, Kami̇l Toker, Zeynep Mi̇ne Solak
Tracheal Intubation In Patients Immobilized By A Rigid Collar: A Comparison Of Glidescope And An Intubating Laryngeal Mask Airway, Semi̇h Özdi̇l, Zehra İpek Arslan Aydin, Zehra Nur Baykara, Kami̇l Toker, Zeynep Mi̇ne Solak
Turkish Journal of Medical Sciences
Background/aim: Intubation must be rapidly performed with the utmost care in cervical trauma patients. We present the first comparison of GlideScope and an intubating laryngeal mask airway (ILMA) regarding insertion and intubation times, intubation success rates, mucosal damage, need for optimization maneuvers, effects on hemodynamic changes, and postoperative minor complications in a simulated cervical injury with a Philadelphia cervical collar. Materials and methods: Ethics committee approval and patient consent were obtained and 94 American Society of Anesthesiology physical status I or II patients were enrolled in this study. Following standard anesthesia monitoring and induction, the Philadelphia-type cervical collar was applied …
Hormone Therapy In Hypospadias Surgery: A Survey On The Current Practice In Turkey, Gülnur Göllü Bahadir, Ergun Ergün, Onur Telli̇, Fari̇d Khanmammadov, Ahmet Murat Çakmak
Hormone Therapy In Hypospadias Surgery: A Survey On The Current Practice In Turkey, Gülnur Göllü Bahadir, Ergun Ergün, Onur Telli̇, Fari̇d Khanmammadov, Ahmet Murat Çakmak
Turkish Journal of Medical Sciences
Background/aim: Nowadays surgical intervention is possible in smaller phalluses and younger children with hypospadias disease. Different hormone treatments with different doses, modalities, indications, and treatment times come along with some disputes. The aim of this study is to evaluate the management approaches in hypospadias surgery of surgeons in regards to hormone preparations. Materials and methods: Questionnaires were sent via e-mail to 110 actively working pediatric surgeons and urologists. The answers of 99 surgeons were evaluated (90%). Two surgeons declared that they did not perform hypospadias surgery. Results: When testosterone usage in penile surgery was questioned, 44.4% of participants (n = …
Management Of Acute Postoperative Hypertension For Reducing Cardiovascular Complications In Cancer Patients: When And How Aggressively?, Ning Lou, Daofeng Wang, Zhi Wang, Wenfeng Ye, Xiao Liu
Management Of Acute Postoperative Hypertension For Reducing Cardiovascular Complications In Cancer Patients: When And How Aggressively?, Ning Lou, Daofeng Wang, Zhi Wang, Wenfeng Ye, Xiao Liu
Turkish Journal of Medical Sciences
Background/aim: We sought to determine what factors cardiovascular complications (CVCs) correlate with in cancer patients with acute postoperative hypertension (APH) and to define when and how aggressively to treat this disorder in the present study. Materials and methods: A retrospective observational study of cancer patients with postoperative hypertension at a single intensive care unit between July 2007 and June 2013 was conducted. The outcome of interest was the incidence of a CVC. Results: There were 1162 patients enrolled, of which 92 (7.9%) experienced one or more CVCs. Preexisting hypertension (OR 38.3, 95% CI 3.2-457.4, P = 0.004) and choice of …
The Effect Of Systemic Isotretinoin Treatment On Skin Biophysicalparameters Among Patients With Acne Vulgaris, Emi̇ne Çölgeçen, Kemal Özyurt, Ayten Ferahbaş Kesi̇koğlu
The Effect Of Systemic Isotretinoin Treatment On Skin Biophysicalparameters Among Patients With Acne Vulgaris, Emi̇ne Çölgeçen, Kemal Özyurt, Ayten Ferahbaş Kesi̇koğlu
Turkish Journal of Medical Sciences
Background/aim: Systemic isotretinoin has been widely considered an effective and safe medical treatment for severe and refractory acne for nearly 3 decades. However, it also appears to cause undesirable cutaneous side effects. The aim of this study was to prospectively measure biophysical parameters of skin function among patients with acne vulgaris before and after 3 months of isotretinoin therapy, including pH, temperature, sebum content, skin hydration, and transepidermal water loss. Materials and methods: The study cohort consisted of 19 patients with acne vulgaris. Noninvasive methods were used to measure the biophysical characteristics of forehead skin. All measurements were repeated following …
Cytomegalovirus Hepatitis In 49 Pediatric Patients With Normal Immunity, Hasan Tezer, Sali̇ha Kanik Yüksek, Belgi̇n Gülhan, Asli Nur Özkaya Parlakay, Ceyda Tuna Kirsaçlioğlu
Cytomegalovirus Hepatitis In 49 Pediatric Patients With Normal Immunity, Hasan Tezer, Sali̇ha Kanik Yüksek, Belgi̇n Gülhan, Asli Nur Özkaya Parlakay, Ceyda Tuna Kirsaçlioğlu
Turkish Journal of Medical Sciences
Background/aim: Cytomegalovirus (CMV) hepatitis is generally asymptomatic or rarely can lead to severe complications in immunocompetent hosts. This study aims to evaluate CMV hepatitis in immunocompetent young children, which is discussed relatively rarely in the literature. Materials and methods: A retrospective review of 49 pediatric patients with CMV hepatitis from January 2005 to December 2010 was performed. Results: The median age of the patients was 5.81 ± 6.49 months and 57.1% were female. Complaints were prolonged jaundice, vomiting, diarrhea, and abdominal distension. Seventeen patients (34.6%) had congenital or probable congenital CMV infection, while 32/49 (65.3%) had perinatal CMV infection. CMV …
Is There A Difference Between Parkinson Disease Patients And A Control Group In Terms Of Urinary Symptoms And Quality Of Life?, Erdal Benli̇, Fahri̇ye Feri̇ha Özer, Yasemi̇n Kaya, Tuba Şazi̇ye Özcan, Ali̇ Ayyildiz
Is There A Difference Between Parkinson Disease Patients And A Control Group In Terms Of Urinary Symptoms And Quality Of Life?, Erdal Benli̇, Fahri̇ye Feri̇ha Özer, Yasemi̇n Kaya, Tuba Şazi̇ye Özcan, Ali̇ Ayyildiz
Turkish Journal of Medical Sciences
Background/aim: The aim of this study is to research whether urinary symptoms and disruption of quality of life observed in Parkinson disease patients are different than those of their healthy peers. Additionally, whether these complaints were affected by characteristics such as age at onset of Parkinson disease, sex, disease duration, and severity was investigated. Materials and methods: This study comprised a total of 79 individuals, 39 Parkinson patients and a control group of 40 individuals. Parkinson diagnosis was provided by a neurology expert according to the UK Parkinson's Disease Society Brain Bank Criteria. All patients were evaluated by a urologist …
The Demographics And Histopathological Features Of Oral Cavity Cancers In Turkey, Mehmet Düzlü, Recep Karamert, Faruk Kadri̇ Bakkal, Raşi̇t Cevi̇zci̇, Hakan Tutar, Mehmet Ekrem Zorlu, Alper Di̇lci̇, Faki̇h Ci̇hat Eravci
The Demographics And Histopathological Features Of Oral Cavity Cancers In Turkey, Mehmet Düzlü, Recep Karamert, Faruk Kadri̇ Bakkal, Raşi̇t Cevi̇zci̇, Hakan Tutar, Mehmet Ekrem Zorlu, Alper Di̇lci̇, Faki̇h Ci̇hat Eravci
Turkish Journal of Medical Sciences
Background/aim: This study aimed to examine the demographics and histopathological features of oral cavity cancers (OCCs) managed in our clinic. Materials and methods: Patients who were diagnosed with OCCs in the Gazi University Otorhinolaryngology Department between the years 1993 and 2013 were retrospectively enrolled in the study. Surgical archive charts and pathology records were reviewed in detail regarding the anatomical and histopathological profiles of the tumors, as well as the demographic data of the patients. Results: Out of 230 patients with OCCs, the most common anatomic location and histopathological diagnosis were found to be the oral tongue (41.4%) and squamous …
Exhaled Carbon Monoxide Is A Marker Of Heavy Nicotine Dependence, Eli̇f Babaoğlu, Ayşegül Karalezli̇, Mükremi̇n Er, Hati̇ce Canan Hasanoğlu, Derya Öztuna
Exhaled Carbon Monoxide Is A Marker Of Heavy Nicotine Dependence, Eli̇f Babaoğlu, Ayşegül Karalezli̇, Mükremi̇n Er, Hati̇ce Canan Hasanoğlu, Derya Öztuna
Turkish Journal of Medical Sciences
Background/aim: Exhaled CO level provides an objective measure of a patient's smoking status. The relationship between CO levels and nicotine dependence is controversial. The aim of this study is to evaluate the relationship between exhaled CO levels and nicotine dependence as well as to demonstrate that exhaled CO levels may be used as a marker of nicotine dependence. Materials and methods: Two hundred eighty-nine patients (132 females, 157 males) were included in the study. Smoking duration, the age of smoking initiation, exhaled CO levels, and Fagerström Test for Nicotine Dependence (FTND) scores were recorded. The relationship between FTND scores and …
Simulation Of Cryolipolysis As A Novel Method For Noninvasive Fat Layer Reduction, Abbas Majdabadi, Mohammad Abazari
Simulation Of Cryolipolysis As A Novel Method For Noninvasive Fat Layer Reduction, Abbas Majdabadi, Mohammad Abazari
Turkish Journal of Medical Sciences
Background/aim: Regarding previous problems in conventional liposuction methods, the need for development of new fat removal operations was appreciated. In this study we are going to simulate one of the novel methods, cryolipolysis, aimed to tackle those drawbacks. Materials and methods: We think that simulation of clinical procedures contributes considerably in efficacious performance of the operations. To do this we have attempted to simulate temperature distribution in a sample fat of the human body. Using Abaqus software we have presented the graphical display of temperature-time variations within the medium. Results: Findings of our simulation indicate that tissue temperature decreases after …
The Effects Of Balneotherapy On Acute, Process-Related, And Cumulative Peripheral Cardiac Responses And Pulmonary Functions In Patients With Musculoskeletal Disorders, Senem Şaş, Şeyda Toprak Çelenay, Derya Özer Kaya
The Effects Of Balneotherapy On Acute, Process-Related, And Cumulative Peripheral Cardiac Responses And Pulmonary Functions In Patients With Musculoskeletal Disorders, Senem Şaş, Şeyda Toprak Çelenay, Derya Özer Kaya
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the effects of balneotherapy on acute, process-related, and cumulative peripheral cardiac responses and pulmonary functions in patients with musculoskeletal disorders. Materials and methods: Ninety-eight patients with musculoskeletal disorders referred to physiotherapy with balneotherapy were recruited. The patients received balneotherapy for 20 min 5 times per week for 2 weeks. Blood pressure and pulse were measured at the 0th, 5th, 10th, 20th, and 30th minutes during the 1st and 10th sessions. All patients were subjected to pulmonary function testing before balneotherapy and after the 10th session. Results: It was found that systolic blood pressure decreased …
Clinical And Histopathological Features Of Asymptomaticpersistent Microscopic Hematuria In Children, Serçi̇n Güven, İbrahi̇m Gökce, Nesli̇han Çi̇çek, Ülger Altuntaş, Nurdan Yildiz, Hari̇ka Alpay
Clinical And Histopathological Features Of Asymptomaticpersistent Microscopic Hematuria In Children, Serçi̇n Güven, İbrahi̇m Gökce, Nesli̇han Çi̇çek, Ülger Altuntaş, Nurdan Yildiz, Hari̇ka Alpay
Turkish Journal of Medical Sciences
Background/aim: We analyzed the clinical and pathological features and prognosis of 106 children with persistent asymptomatic microscopic hematuria (PAMH) with or without mild proteinuria. Materials and methods: This was a retrospective study of 106 children who were referred to our clinics from 2000 to 2013 for evaluation of PAMH. Results: Among the 106 patients, 69 (65%) were female and 37 (35%) were male. The patients were divided into two groups: 101 patients with isolated microscopic hematuria (IMH) and 5 patients with asymptomatic microscopic hematuria and mild proteinuria (AMHP). Renal biopsy was performed in all 5 children with AHMP: 2 patients …
Evaluation Of Epidemiological Characteristics And Risk Factors Affecting Mortality In Patients With Candidemia, Fatma Yilmaz Karadağ, Pinar Ergen, Özlem Aydin, Arzu Doğru, Berri̇n Tanidir, Mustafa Haluk Vahaboğlu
Evaluation Of Epidemiological Characteristics And Risk Factors Affecting Mortality In Patients With Candidemia, Fatma Yilmaz Karadağ, Pinar Ergen, Özlem Aydin, Arzu Doğru, Berri̇n Tanidir, Mustafa Haluk Vahaboğlu
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to determine epidemiologic characters of patients with candidemia and to evaluate risk factors that can affect mortality rates among these patients. Materials and methods: Patients admitted to the İstanbul Medeniyet University Göztepe Training Hospital between 2009 and 2011 who had a positive blood culture for Candida spp. during hospitalization were studied retrospectively for demographic characteristics and risk factors. Statistical comparisons were estimated with the Stata 12 package. Independent variables associated with mortality were estimated by Cox regression analyses. Results: A total of 89 patients were identified with a positive blood culture. Of the …
Clinical Characteristics And Outcome Of Brucella Endocarditis, Na Du, Feng Wang
Clinical Characteristics And Outcome Of Brucella Endocarditis, Na Du, Feng Wang
Turkish Journal of Medical Sciences
Background/aim: Brucella endocarditis, which is a rare condition, is the most common cause of death in human brucellosis, leading to severe cardiac complications. By collecting and analyzing clinical cases, we analyzed the clinical characteristics and outcome of Brucella endocarditis in endemic areas in China. Materials and methods: Presented here are 5 cases of Brucella endocarditis, all managed uniformly. We present the clinical, serological, and echocardiographic features; the therapeutic approach; and the follow-up of five patients with Brucella endocarditis. Results: There was a predominance of aortic involvement (4 cases) and a high incidence of left ventricular failure (5 cases). Polymerase chain …
Chronic Cough: Clinical Characteristics And Etiologies Of 510 Cases, Guiyuan Jiang, Xinying Huang, Tianlin Li, Dongping Xu
Chronic Cough: Clinical Characteristics And Etiologies Of 510 Cases, Guiyuan Jiang, Xinying Huang, Tianlin Li, Dongping Xu
Turkish Journal of Medical Sciences
Background/aim: To investigate the clinical features and underlying etiologies of chronic cough (CC). Materials and methods: Five hundred and ten CC patients were enrolled. The phases, characteristics and associated clinical manifestations of CC among the gastroesophageal reflux cough (GERC), cough-variant asthma (CVA), and upper airway cough syndrome (UACS) groups were compared, and the diagnostic values of each group were evaluated by multiple regression analysis. Results: In the 510 patients, 404 had CC with single etiology-GERC (n = 175), CVA (n = 134), and UACS (n = 95). The characteristic features of GERC included gastric acid backflow symptoms such as sour-tasting …
Pityriasis Rosea: A Natural History Of Pediatric Cases In Thecentral Anatolia Region Of Turkey, Emi̇ne Çölgeçen, Çi̇ğdem Kader, Yilmaz Ulaş, Pinar Öztürk, Öznur Küçük, Mehmet Balci
Pityriasis Rosea: A Natural History Of Pediatric Cases In Thecentral Anatolia Region Of Turkey, Emi̇ne Çölgeçen, Çi̇ğdem Kader, Yilmaz Ulaş, Pinar Öztürk, Öznur Küçük, Mehmet Balci
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the demographic, clinical, and epidemiological features of pityriasis rosea (PR) in a cohort of 46 children in Yozgat, a city in the Central Anatolia Region of Turkey. Materials and methods: Forty-six children with PR were monitored at regular intervals (1, 2, 4, and 12 weeks) for 3 months from the time of diagnosis. A complete evaluation of the patient was performed at each visit. Results: The average age of patients at time of diagnosis was 12 ± 3.9 years. Cases were most common in the winter (rainy, snowy months; n = 14, 31%). Fifteen …
Sleep Quality In Opioid-Naive And Opioid-Dependent Patientson Methadone Maintenance Therapy In Malaysia, Zalina Zahari, Muslih Abdulkarim Ibrahim, Soo Choon Tan, Nasir Mohamad, Rusli Ismail
Sleep Quality In Opioid-Naive And Opioid-Dependent Patientson Methadone Maintenance Therapy In Malaysia, Zalina Zahari, Muslih Abdulkarim Ibrahim, Soo Choon Tan, Nasir Mohamad, Rusli Ismail
Turkish Journal of Medical Sciences
Background/aim: Sleep disturbances may contribute to poor treatment outcomes in opioid-dependent patients. The extent to which the sleep profiles of opioid-dependent patients differ from those of the general Malaysian population is not documented. This study compared opioid-naive subjects and opioid-dependent patients on methadone maintenance therapy (MMT) in terms of their sleep quality. Materials and methods: Participants comprised Malay male opioid-naive subjects (n = 159) and opioid-dependent patients (n = 160) from MMT clinics in Kelantan, Malaysia, between March and October 2013. Sleep quality was evaluated using the translated and validated Malay version of the Pittsburgh Sleep Quality Index (PSQI). Results: …
Does Cpap Treatment Affect The Voice?, Güleser Saylam, Mustafa Şahi̇n, Di̇lek Demi̇ral, Ömer Bayir, Meli̇ke Bağnu Yüceege, Emel Çadalli Tatar, Mehmet Hakan Korkmaz
Does Cpap Treatment Affect The Voice?, Güleser Saylam, Mustafa Şahi̇n, Di̇lek Demi̇ral, Ömer Bayir, Meli̇ke Bağnu Yüceege, Emel Çadalli Tatar, Mehmet Hakan Korkmaz
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate alterations in voice parameters among patients using continuous positive airway pressure (CPAP) for the treatment of obstructive sleep apnea syndrome. Materials and methods: Patients with an indication for CPAP treatment without any voice problems and with normal laryngeal findings were included and voice parameters were evaluated before and 1 and 6 months after CPAP. Videolaryngostroboscopic findings, a self-rated scale (Voice Handicap Index-10, VHI-10), perceptual voice quality assessment (GRBAS: grade, roughness, breathiness, asthenia, strain), and acoustic parameters were compared. Results: Data from 70 subjects (48 men and 22 women) with a mean …
Acute Exudative Tonsillitis In Adults: The Use Of The Centor Scoreand Some Laboratory Tests, Yavuz Furuncuoğlu, Fi̇li̇z Sağlam, Ahmet Kutluhan
Acute Exudative Tonsillitis In Adults: The Use Of The Centor Scoreand Some Laboratory Tests, Yavuz Furuncuoğlu, Fi̇li̇z Sağlam, Ahmet Kutluhan
Turkish Journal of Medical Sciences
Background/aim: The aim of our study was to determine the usefulness of the Centor score and some basic laboratory tests (complete blood count and C-reactive protein) for the differential diagnosis of exudative tonsillitis due to Group A β-hemolytic streptococcus (GABHS) or due to non-GABHS agents. Materials and methods: The data of clinical and laboratory characteristics of the patients diagnosed with exudative tonsillitis were collected and statistically compared between those having positive GABHS throat culture result and those who were negative for any bacterial agent. Results: Totally 899 adult patients were included in our study; 56 (6.2%) of them were positive …
Treatment Efficacy And Superinfection Rates In Complicated Urinarytract Infections Treated With Ertapenem Or Piperacillin Tazobactam, Murat Di̇zbay, Hasan Selçuk Özger, Ömer Karaşahi̇n, Emi̇ne Füsun Karaşahi̇n
Treatment Efficacy And Superinfection Rates In Complicated Urinarytract Infections Treated With Ertapenem Or Piperacillin Tazobactam, Murat Di̇zbay, Hasan Selçuk Özger, Ömer Karaşahi̇n, Emi̇ne Füsun Karaşahi̇n
Turkish Journal of Medical Sciences
Background/aim: In this retrospective study, the efficacy of ertapenem and piperacillin tazobactam was compared in the treatment of complicated urinary tract infections (cUTIs). Treatment responses were also evaluated for both antibiotics. Materials and methods: A total of 230 patients were enrolled in the study. Of these, 170 received ertapenem and 60 received piperacillin-tazobactam. Results: In both groups, urine cultures after 48 h were negative for the initial uropathogen. The frequency of superinfection was 29.4% in the ertapenem group and 8.3% in the piperacillin-tazobactam group over the duration of treatment (P < 0.05). Urinary catheterization increased the superinfection risk 2.88-fold in the ertapenem group and diabetes mellitus increased the risk 8.50-fold in the piperacillin-tazobactam group (CI: 1.44-5.76 and 1.16-62.09, respectively, P < 0.05). The main pathogen isolated from superinfection in the ertapenem group after 48 h was Enterococcus spp. (71.4%). Conclusion: Both ertapenem and piperacillin-tazobactam were effective in the treatment of cUTIs caused by ESBL-producing microorganisms. A high frequency of superinfection in the ertapenem group was the result of Enterococcus and Pseudomonas spp., against which ertapenem is not active. In the presence of urinary catheterization, diabetes mellitus, and urological intervention, patients should be closely monitored for the development of a superinfection, especially patients receiving ertapenem.
Plasma Levels Of Serotonin, Gastrointestinal Symptoms,And Sleep Problems In Children With Autism, Sorayya Khkheirouri, Parinaz Kalejahi, Seyyed Gholamreza Noorazar
Plasma Levels Of Serotonin, Gastrointestinal Symptoms,And Sleep Problems In Children With Autism, Sorayya Khkheirouri, Parinaz Kalejahi, Seyyed Gholamreza Noorazar
Turkish Journal of Medical Sciences
Background/aim: Autism is a neurodevelopmental disorder identified with higher frequency of serotonin abnormalities and gastrointestinal (GI) and sleep problems. This study aimed to evaluate the plasma levels of serotonin, GI symptoms, and sleep problems, and their relationship with autism severity in children with autism. Materials and methods: Thirty-five children with autism and 31 healthy subjects were studied. GI problems, sleep disorders, and severity of disorder were assessed. Plasma serotonin was determined using ELISA. Results: There was no significant association between GI problems and autism severity, but a significant positive correlation was seen between different indicators of sleep disorder and severity …