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Articles 2911 - 2940 of 8080
Full-Text Articles in Medicine and Health Sciences
Modifications Of Mice Gut Microflora Following Oral Consumption Oflactobacillus Acidophilus And Bifidobacterium Bifidum Probiotics, Hossein Khavari-Daneshvar, Maryam Mosavi, Hamid Khodayari, Ebrahim Rahimi, Peyman Ranji, Amir Hossein Mohseni, Reyhaneh Mahmudian, Farzad Shidfar, Shahram Agah, Ali Mohammad Alizadeh
Modifications Of Mice Gut Microflora Following Oral Consumption Oflactobacillus Acidophilus And Bifidobacterium Bifidum Probiotics, Hossein Khavari-Daneshvar, Maryam Mosavi, Hamid Khodayari, Ebrahim Rahimi, Peyman Ranji, Amir Hossein Mohseni, Reyhaneh Mahmudian, Farzad Shidfar, Shahram Agah, Ali Mohammad Alizadeh
Turkish Journal of Medical Sciences
Background/aim: Thirty male BALB/c mice were equally divided into three groups: control, L. acidophilus, and B. bifidum for the assessment of the probiotics' stability in the gut microflora. Materials and methods: First, the gut microflora of the mice was checked every 3 days (days 3, 6, 9, and 12) without probiotic consumption, and then the mice were daily given orally 1.5 g of probiotics in 30 cc of drinking water. The consumption of probiotics was then stopped for recovery and then the consumption continued for 5 months. Results: On day 9 after the consumption of the probiotics, L. acidophilus and …
Efficient Production Of Nanobodies Against Urease Activity Ofhelicobacter Pylori In Pichia Pastoris, Shahrbanoo Pourasadi, Seyed Latif Mousavi Gargari, Masoumeh Rajabibazl, Shahram Nazarian
Efficient Production Of Nanobodies Against Urease Activity Ofhelicobacter Pylori In Pichia Pastoris, Shahrbanoo Pourasadi, Seyed Latif Mousavi Gargari, Masoumeh Rajabibazl, Shahram Nazarian
Turkish Journal of Medical Sciences
Background/aim: Helicobacter pylori is a major health problem. One of the therapeutic approaches is administration of antibody against H. pylori. The methylotrophic Pichia pastoris is a suitable host for expression of recombinant antibody fragments. The aims of this study were the expression and the evaluation of camelid nanobody in the yeast Pichia pastoris. Materials and methods: The camelid-derived heavy-chain antibody (nanobody) against the UreC subunit of urease from H. pylori was subcloned in the pPink-HC shuttle vector and transferred into Escherichia coli TOP10. After digestion and purification, the shuttle vector was transformed in the PichiaPink expression system. The expression was …
Evaluation Of Cytotoxic, Membrane, And Dna Damaging Effects Of Thymus Revolutuscélak Essential Oil On Different Cancer Cells, Aysun Özkan, Ayşe Erdoğan
Evaluation Of Cytotoxic, Membrane, And Dna Damaging Effects Of Thymus Revolutuscélak Essential Oil On Different Cancer Cells, Aysun Özkan, Ayşe Erdoğan
Turkish Journal of Medical Sciences
Background/aim: In this study, we evaluated Thymus revolutus Célak essential oil and its two main constituents, γ-terpinene and p-cymene, as potential oxidative agents against lung cancer and epidermoid carcinoma cells. Materials and methods: Cell viability assessment was made by CellTiter-Blue® cell viability and 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) assay after treatment with 5?600 ?g/mL concentrations of essential oil, γ-terpinene, and p-cymene. Malondialdehyde and 8-hydroxy-2'-deoxyguanosine levels in parental H1299, epirubicin-resistant (drug-resistant) H1299, A549, and A431 cells were also assayed after essential oil, γ-terpinene, and p-cymene had been administered for 24 h. Glutathione S-transferase (GST), glutathione peroxidase (GPx), glutathione reductase (GRx), and glucose …
Psychosocial Functioning In Pediatric Patients With Pectus Excavatum And Pectus Carinatum, Ali̇ye Tuğba Bahadir, Pinar Kuru, Ayli̇n Çakiroğlu, Ceyda Afacan, Mustafa Yüksel
Psychosocial Functioning In Pediatric Patients With Pectus Excavatum And Pectus Carinatum, Ali̇ye Tuğba Bahadir, Pinar Kuru, Ayli̇n Çakiroğlu, Ceyda Afacan, Mustafa Yüksel
Turkish Journal of Medical Sciences
Background/aim: Pectus excavatum and pectus carinatum are the most commonly seen anterior chest wall deformities. Recent studies reveal that minimal invasive repair of pectus deformities improves the quality of life. Our aim is to assess the psychosocial functioning and sociodemographic characteristics of pediatric patients with pectus deformities and evaluate the differences between patients operated on with minimal invasive repair techniques and nonoperated patients. Materials and methods: Thirty-two patients with pectus deformities who were operated on 6 months or more before and 31 nonoperated patients participated in the study. The Children's Depression Inventory, Piers-Harris Children's Self-Concept Scale, Capa Social Phobia Scale …
Antioxidants Status In Type 2 Diabetic Patients In Morocco, Rachid Eljaoudi, Naoual Elomri, Meryem Laamarti, Yahia Cherrah, Taoufik Amezyane, Driss Ghafir, Azeddine Ibrahimi
Antioxidants Status In Type 2 Diabetic Patients In Morocco, Rachid Eljaoudi, Naoual Elomri, Meryem Laamarti, Yahia Cherrah, Taoufik Amezyane, Driss Ghafir, Azeddine Ibrahimi
Turkish Journal of Medical Sciences
Background/aim: Type 2 diabetes is a heterogeneous and multifactorial metabolic disorder with some relationship to oxidative stress (OS). Since no studies were conducted in the Moroccan population, this clinical investigation aimed at evaluating the antioxidants status in Moroccan patients with type 2 diabetes. Materials and methods: Blood samples of 60 type 2 diabetic patients and 40 healthy controls subjects were analyzed for determination of glycemia, hemoglobin, CRP, glycated hemoglobin, lipid parameters, malondialdehyde (MDA), vitamins E and C, copper (Cu), zinc (Zn), and selenium (Se). Results: CRP and triglycerides were higher in the diabetic group while high-density lipoprotein levels were significantly …
The Evaluation Of Cervical Spinal Angle In Patients With Acute And Chronic Neck Pain, Ayhan Aşkin, Korhan Bariş Bayram, Ümi̇t Seçi̇l Demi̇rdal, Emel Atar, Çi̇ğdem Ari̇foğlu Karaman, Ece Güvendi̇, Ali̇ye Tosun
The Evaluation Of Cervical Spinal Angle In Patients With Acute And Chronic Neck Pain, Ayhan Aşkin, Korhan Bariş Bayram, Ümi̇t Seçi̇l Demi̇rdal, Emel Atar, Çi̇ğdem Ari̇foğlu Karaman, Ece Güvendi̇, Ali̇ye Tosun
Turkish Journal of Medical Sciences
Background/aim: Clinicians associate the changes in cervical lordosis with neck pain, but there is no clear consensus on this. We aimed to investigate the relationships of cervical angles, neck pain, disability, and the psychological status of the patients with acute and chronic neck pain. Materials and methods: A total of 110 patients with neck pain were included in this study. Demographic and clinical characteristics of the patients were recorded. The lordosis angle was determined by the posterior tangent method. A visual analog scale (VAS), the Neck Disability Index (NDI), and the Hospital Anxiety and Depression (HAD) scale were administered to …
Risk Factors Associated With Poor Outcome In Diabetic Foot Ulcer Patients, Saira Saleem, Nazim Hayat, Irshad Ahmad, Tanvir Ahmad, Abdulgaffar Rehan
Risk Factors Associated With Poor Outcome In Diabetic Foot Ulcer Patients, Saira Saleem, Nazim Hayat, Irshad Ahmad, Tanvir Ahmad, Abdulgaffar Rehan
Turkish Journal of Medical Sciences
Background/aim: Diabetic foot ulcers and related complications are a major cause of morbidity and hospital admissions. Our aim was to evaluate the risk factors associated with poor outcome in diabetic foot ulcers. Materials and methods: A prospective study was conducted on patients with diabetic foot ulceration attending the Madinah Teaching Hospital from June 2014 to December 2015. Potential risk factors and laboratory test results at presentation were recorded and their association with outcome (healing vs. amputation) was analyzed using IBM SPSS Statistics for Windows, Version 22.0. Results: In total, 112 patients were studied during our study period. The majority of …
Possible Triggering Factors And Comorbidities In Newlydiagnosed Autoimmune Bullous Diseases, Sevgi̇ Akarsu, Özlem Özbağçivan, Necla Dolaş, Şebnem Aktan
Possible Triggering Factors And Comorbidities In Newlydiagnosed Autoimmune Bullous Diseases, Sevgi̇ Akarsu, Özlem Özbağçivan, Necla Dolaş, Şebnem Aktan
Turkish Journal of Medical Sciences
Background/aim: The distribution and the demographic, etiological, and clinical features of autoimmune bullous diseases (ABDs) vary according to geographic regions of the world. The limited number of reported studies in Turkey are mostly retrospective and generally include only pemphigus. The aim of our study was to evaluate the demographic data, clinical features, associated triggering factors, and comorbidities in patients newly diagnosed with ABDs. Materials and methods: In this descriptive and prospective study, the demographic data, inhabited regions, smoking and drinking habits, presence of comorbidities, and specific and general potential triggering factors of ABDs considered by the patients were examined. Furthermore, …
Pain, Depression Levels, Fatigue, Sleep Quality, And Quality Of Life Inelderly Patients With Rheumatoid Arthritis, İlknur Albayrak Gezer, Ayşe Balkarli, Beray Can, Si̇nan Bağçaci, Sami̇ Küçükşen, Adem Küçük
Pain, Depression Levels, Fatigue, Sleep Quality, And Quality Of Life Inelderly Patients With Rheumatoid Arthritis, İlknur Albayrak Gezer, Ayşe Balkarli, Beray Can, Si̇nan Bağçaci, Sami̇ Küçükşen, Adem Küçük
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to evaluate and determine the relationships (if any) among pain, depression levels, fatigue, sleep quality, and quality of life in patients with rheumatoid arthritis (RA) aged 65 years and over, and to compare the results with those of RA patients under 65 years of age. Materials and methods: The study included 52 patients with RA aged 65 years and over (Group 1) and 84 patients with RA under 65 years of age (Group 2). Pain, depression levels, fatigue, sleep quality, quality of life, and disease activity of all of the participants were evaluated …
Effects Of Artcure Diffusional Patch Application On Pain And Functional Status In Lumbar Disc Herniation Patients: A Prospective Randomized Controlled Study, Mahmut Uğurlu, Mehmet Atif Erol Akseki̇li̇, Berat Meryem Alkan, Hali̇l Kara, Ceyhun Çağlar
Effects Of Artcure Diffusional Patch Application On Pain And Functional Status In Lumbar Disc Herniation Patients: A Prospective Randomized Controlled Study, Mahmut Uğurlu, Mehmet Atif Erol Akseki̇li̇, Berat Meryem Alkan, Hali̇l Kara, Ceyhun Çağlar
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to assess the efficacy of the Artcure Diffusional Patch, which contains a mixture of 6 herbal oils (oleum thymi, oleum limonis, oleum nigra, oleum rosmarini, oleum chamomilla, oleum lauriexpressum) and has a hypoosmolar lipid structure, in the conservative treatment of lumbar disc herniation patients and to show the advantages and/or possibility of using this as an alternative method to surgery. Materials and methods: Of the 120 patients enrolled, 79 clinically diagnosed patients were included in the study. Clinical evaluations were performed on patients who had findings of protrusion or extrusion in their magnetic …
An Investigation Of Sagittal Thoracic Spinal Curvature And Mobility In Subjects With And Without Chronic Neck Pain: Cut-Off Points And Pain Relationship, Derya Özer Kaya, Şeyda Toprak Çelenay
An Investigation Of Sagittal Thoracic Spinal Curvature And Mobility In Subjects With And Without Chronic Neck Pain: Cut-Off Points And Pain Relationship, Derya Özer Kaya, Şeyda Toprak Çelenay
Turkish Journal of Medical Sciences
Background/aim: Thoracic spine insufficiency is a subject of interest in neck problems. The aim was to investigate thoracic spinal curvature and mobility in subjects with and without chronic neck pain (CNP), cut-off points, and the relationship with pain. Materials and methods: Fifty-six patients with CNP (CNP group) and 53 healthy volunteers (control group) were included. Neck pain intensity of the patients was assessed by visual analogue scale and sagittal thoracic curvature and mobility of all participants were assessed by Spinal Mouse (Idiag, Fehraltorf, Switzerland). Results: Thoracic curvature was higher (P < 0.001) and mobility lower in the CNP group in comparison to the control group (P = 0.013). There was a positive correlation between pain intensity and thoracic curvature (r = 0.391, P < 0.001), while there was a negative correlation between pain intensity and thoracic mobility (r = -0.260, P = 0.006). For detecting neck pain, it was observed that the cut-off points for thoracic curvature and mobility were 45.5° and 30.0°, respectively. Conclusions: An increase in thoracic curvature of more than 45° and a decrease in mobility more than 30° may be critical for CNP patients.
The Turkish Version Of The Physical Activity Scale For Theelderly (Pase): Its Cultural Adaptation, Validation, And Reliability, Ender Ayvat, Muhammed Kilinç, Nuray Kirdi
The Turkish Version Of The Physical Activity Scale For Theelderly (Pase): Its Cultural Adaptation, Validation, And Reliability, Ender Ayvat, Muhammed Kilinç, Nuray Kirdi
Turkish Journal of Medical Sciences
Background/aim: This study aimed to describe the cultural adaptation of the Turkish Physical Activity Scale for the Elderly (PASE) and to examine the reliability and validity of the scale in older Turkish adults. Materials and methods: Eighty elderly people were recruited for the study. The assessments included the PASE, the International Physical Activity Questionnaire (IPAQ), the Short Physical Performance Battery and Short Form-36 Quality of Life Questionnaire (SF-36), and the Mini Mental State Test. Outcome measures were conducted twice within a week (test-retest) for reliability. Results: Cronbach's α coefficient was 0.714 for the initial evaluation. The intraclass correlation coefficient for …
Comparative Analysis Of Selected Cagpai Genes And Different Vaca Genotypes In Iranian And Turkish H. Pylori-Positive Patients Suffering From Gastric Adenocarcinoma And Active Chronic Gastritis, Ali Bahadori, Mohammad Hossein Somi, Fi̇gen Doran, Amir Taher Eftekharsadat, Suna Kizilyildirim, Mahsa Esmaeillou, Maryam Yassi, Başak Bedi̇r, Fati̇h Köksal
Comparative Analysis Of Selected Cagpai Genes And Different Vaca Genotypes In Iranian And Turkish H. Pylori-Positive Patients Suffering From Gastric Adenocarcinoma And Active Chronic Gastritis, Ali Bahadori, Mohammad Hossein Somi, Fi̇gen Doran, Amir Taher Eftekharsadat, Suna Kizilyildirim, Mahsa Esmaeillou, Maryam Yassi, Başak Bedi̇r, Fati̇h Köksal
Turkish Journal of Medical Sciences
Background/aim: Helicobacter pylori is a pathogen that colonizes a majority of the world's population. Genetic diversity within the virulence genes of bacteria such as cagPAI and vacA may have a modified effect on the pathogenic potential of the bacteria. This study aimed to investigate which genes can be suggested as potentially related virulence factors for H. pylori-associated active chronic gastritis and stomach adenocarcinoma in the northwest of Iran and south of Turkey. Materials and methods: Formalin-fixed, paraffin-embedded stomach biopsy tissue samples were obtained from Iranian and Turkish patients from selected geographical regions. The prevalence of selected cagPAI genes and vacA …
Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay
Effects Of A Closed System Suction Connector On Airwayresistance In Ventilated Neonates, Sezi̇n Ünal, Nuri̇ye Ebru Ergenekon, Ebru Kazanci, Selma Aktaş, Feri̇t Kulali, İbrahi̇m Murat Hirfanoğlu, Canan Türkyilmaz, Yildiz Atalay
Turkish Journal of Medical Sciences
Background/aim: Increased airway resistance reduces the effectiveness of ventilation treatment. Endotracheal tubes (ETTs) and connectors contribute to resistance. However, the effect of a closed system suction (CSS) connector is not well known. We compared the in vivo resistance occurring with a CSS connector with that of the standard connector. Materials and methods: This prospective study was conducted at Gazi University Hospital's neonatal intensive care unit. Intubated neonates were studied for two cycles; each cycle contained two periods of ETT + connector pairs (15 min/period) as follows: cycle 1 [A: long ETT + standard connector; B: long ETT + CSS connector] …
Evaluation Of Polyneuropathy And Associated Risk Factors Inchildren With Type 1 Diabetes Mellitus, Hande Namal Türkyilmaz, Orki̇de Güzel, Selvi̇naz Edi̇zer, Aycan Ünalp
Evaluation Of Polyneuropathy And Associated Risk Factors Inchildren With Type 1 Diabetes Mellitus, Hande Namal Türkyilmaz, Orki̇de Güzel, Selvi̇naz Edi̇zer, Aycan Ünalp
Turkish Journal of Medical Sciences
Background/aim: Diabetes mellitus (DM) is one of the most common metabolic diseases seen in the world today. Diabetic neuropathy (DN) is a chronic complication of the disease that is rarely reported in children, since it has a relatively longer latency period. Our main objective in this study is to determine the incidence rate of DN in pediatric DM patients and assess the risk factors associated with DN. Materials and methods: Data from 111 patients from January 2011 to May 2014 were reviewed in a retrospective manner. Nerve conduction studies were performed as the gold standard in diagnosis. Results: The incidence …
A Comparison Of Culture And Pcr Methods For Identifying Propionibacterium Acnes In Lesions Isolated From Patients With Acne, Negin Naghdi, Masood Ghane
A Comparison Of Culture And Pcr Methods For Identifying Propionibacterium Acnes In Lesions Isolated From Patients With Acne, Negin Naghdi, Masood Ghane
Turkish Journal of Medical Sciences
Background/aim: One of the factors that affect the occurrence of acne is the presence of Propionibacterium acnes. The present study was conducted to compare the culture and polymerase chain reaction (PCR) methods for identifying P. acnes in lesions isolated from patients with acne. Materials and methods: To examine the presence of P. acnes, 70 samples of acne lesions were collected. Microbial culture and the PCR molecular technique were used to identify P. acnes. Results: Of the total of 70 samples, 14 cases (20%) were identified as P. acnes positive using microbial culture and 58 cases (82.85%) using PCR. The results …
Development Of A New Real-Time Pcr Screening Kit For Hbs And Common Beta-Thalassemia Mutations Observed In Turkey, Derya Kan Karaer, Mehmet Ali̇ Ergün, Hati̇ce Ilgin Ruhi̇, Jale Öztürk, Hali̇l Kara, Deni̇z Rei̇soğlu Çakmak, Tali̇hanur Aydoğmuş, Ferda Emri̇ye Perçi̇n
Development Of A New Real-Time Pcr Screening Kit For Hbs And Common Beta-Thalassemia Mutations Observed In Turkey, Derya Kan Karaer, Mehmet Ali̇ Ergün, Hati̇ce Ilgin Ruhi̇, Jale Öztürk, Hali̇l Kara, Deni̇z Rei̇soğlu Çakmak, Tali̇hanur Aydoğmuş, Ferda Emri̇ye Perçi̇n
Turkish Journal of Medical Sciences
Background/aim: IVSI-110 (G>A), IVSI-6 (T>C), IVSII-1 (G>A), IVSII-745 (C>G), IVSI-1 (G>A), and HbS are mutations covering 76% of all the β-globin mutations in the Turkish population. In this study, our aim is to develop a reliable, fast, real-time kit for these mutations using the TaqMan probe method. Materials and methods: This study included 100 individuals with beta-thalassemia or sickle cell anemia who had unknown mutations, and 21 controls with known mutations. Results: We designed a kit containing the IVSI-110 (G>A), IVSI-6 (T>C), IVSII-1 (G>A), IVSII-745 (C>G), IVSI-1 (G>A), and HbS …
Investigation Of The Behavioral And Neurochemical Effects Of Monosodium Glutamate On Neonatal Rats, Ayşen Çetin Kardeşler, Eyup Başkale
Investigation Of The Behavioral And Neurochemical Effects Of Monosodium Glutamate On Neonatal Rats, Ayşen Çetin Kardeşler, Eyup Başkale
Turkish Journal of Medical Sciences
Background/aim: The objective of this study was to investigate and analyze the behavioral and neurochemical effects of monosodium glutamate (MSG) injections at various and subsequent dosages on male Wistar rats during the neonatal period. Materials and methods: In order to determine the behavioral and neurochemical effects of MSG, the experiment was implemented on neonatal male Wistar rats and the test was repeated for various MSG dosages. After completing the experiment, additionally, levels of dopamine, GABA, catecholamine (dopamine, noradrenaline, and adrenaline) and glutamate in the brain cells of the decapitated rats were also measured using the ELISA method. Results: Considering the …
The Effect Of Trimetazidine On Renal Oxidative Stress In Partialand Complete Ureteral Obstructions In A Rat Model, Sema Nur Ayyildiz, Ali̇ Ayyildiz, Erdal Benli̇, Selma Cirrik, Rüştü Cankon Germi̇yanoğlu, Tevfi̇k Noyan, Abdullah Çirakoğlu
The Effect Of Trimetazidine On Renal Oxidative Stress In Partialand Complete Ureteral Obstructions In A Rat Model, Sema Nur Ayyildiz, Ali̇ Ayyildiz, Erdal Benli̇, Selma Cirrik, Rüştü Cankon Germi̇yanoğlu, Tevfi̇k Noyan, Abdullah Çirakoğlu
Turkish Journal of Medical Sciences
Background/aim: Renal oxidative stress occurs in ureteral obstructions. The purpose of this study was to investigate the effect of the antioxidant and antiischemic agent trimetazidine (TMZ) on oxidative stress following ureteral obstruction. Materials and methods: Ten groups were established. Sham groups were checked as controls after 1 and 3 weeks. The other 8 groups had partial or complete ureteral obstruction while receiving or not receiving trimetazidine (TMZ) at 5 mg/kg daily and were evaluated after either 1 week or 3 weeks. Creatinine and cystatin C measurements were performed in the serum. Malondialdehyde, myeloperoxidase, catalase, and glutathione peroxidase activity were measured …
Relationship Between Kinesiophobia And Pain, Quality Of Life, Functional Status, Disease Activity, Mobility, And Depression In Patients With Ankylosing Spondylitis, Deran Oskay, Zeynep Tuna, İrem Düzgün, Bülent Elbasan, Yavuz Yakut, Abdurrahman Tufan
Relationship Between Kinesiophobia And Pain, Quality Of Life, Functional Status, Disease Activity, Mobility, And Depression In Patients With Ankylosing Spondylitis, Deran Oskay, Zeynep Tuna, İrem Düzgün, Bülent Elbasan, Yavuz Yakut, Abdurrahman Tufan
Turkish Journal of Medical Sciences
Background/aim: Our aim was to investigate the association of kinesiophobia with pain, quality of life, clinical measures, and depression in patients with ankylosing spondylitis (AS). Materials and methods: Patients with AS (n: 163) were enrolled in the study. Kinesiophobia was evaluated with the Tampa Scale of Kinesiophobia (TSK), pain with a visual analog scale (VAS), mobility with Bath Ankylosing Spondylitis Metrology Index (BASMI), disease activity with the Bath AS Disease Activity Index (BASDAI), functional status with the Bath AS Functional Index (BASFI), depression level with Beck's Depression Inventory (BDI), and quality of life with the AS Quality of Life Questionnaire …
Evaluation Of Risk Factors For The Recurrence Of Colorectal Polyps And Colorectal Cancer, Öztürk Ateş, Bülent Si̇vri̇, Saadetti̇n Kiliçkap
Evaluation Of Risk Factors For The Recurrence Of Colorectal Polyps And Colorectal Cancer, Öztürk Ateş, Bülent Si̇vri̇, Saadetti̇n Kiliçkap
Turkish Journal of Medical Sciences
Background/aim: Colorectal adenomatous polyps are precursors of colorectal cancer (CRC), which can be prevented with surveillance colonoscopy. This study aimed to assess risk factors for the recurrence of colorectal polyps and CRC following polypectomy. Materials and methods: In this single-center trial, a total of 510 patients who applied to the endoscopy unit of Hacettepe University Hospital for various reasons and who were diagnosed with at least one colorectal adenomatous polyp between 2000 and 2010 were retrospectively analyzed. Patients with colorectal adenomatous polyps or CRC recurrences were examined in terms of clinical and histological risk factors. Results: A total of 190 …
The Effects Of The Number Of Physical Therapy Sessions On Pain, Disability,And Quality Of Life In Patients With Chronic Low Back Pain, Burcu Meti̇n Ökmen, Engi̇n Koyuncu, Bi̇lal Uysal, Neşe Özgi̇rgi̇n
The Effects Of The Number Of Physical Therapy Sessions On Pain, Disability,And Quality Of Life In Patients With Chronic Low Back Pain, Burcu Meti̇n Ökmen, Engi̇n Koyuncu, Bi̇lal Uysal, Neşe Özgi̇rgi̇n
Turkish Journal of Medical Sciences
Background/aim: The aim of this study was to investigate and compare the effect of different physical therapy (PT) session numbers on pain, impairment. and quality of life in patients with chronic low back pain (LBP).Materials and methods: In this prospective, randomized-controlled, single-blind trial, a total of 60 patients with chronic LBP were divided into 2 groups with simple randomization within the scope of the study. A PT program of a total of 10 sessions was applied for patients in Group 10 (n = 30) and a total of 15 sessions for patients in Group 15 (n = 30). The main …
Frequencies And Distributions Of Sex Chromosome Abnormalities In Females With The Turner Phenotype: A Long-Term Retrospective Study In The Southern Region Of Turkey, Ni̇lgün Tanriverdi̇, Osman Demi̇rhan, Di̇lara Süleymanova Karahan, Ayfer Pazarbaşi
Frequencies And Distributions Of Sex Chromosome Abnormalities In Females With The Turner Phenotype: A Long-Term Retrospective Study In The Southern Region Of Turkey, Ni̇lgün Tanriverdi̇, Osman Demi̇rhan, Di̇lara Süleymanova Karahan, Ayfer Pazarbaşi
Turkish Journal of Medical Sciences
Background/aim: The genetic background of Turner syndrome (TS) is highly variable. The correlation between genotype and phenotype is not yet well understood. The aim of this study was to describe the frequencies and distributions of Turner karyotypes and to discuss the phenotype/genotype relation in a very large group of individuals with TS. Materials and methods: The karyotype results of 248 female participants were evaluated retrospectively.Results: Of 248 females with the Turner phenotype, 14.5% had normal karyotypes and 85.5% had Turner karyotypes. About 72.2% of the abnormalities were numerical aberrations and 27.8% were structural aberrations. The most frequent karyotype was monosomy …
Prevalence And Risk Factors For Helicobacter Pylori Infection In Southwest China: A Study Of Health Examination Participants Based On 13c-Urea Breath Test, Jie Liu, Yonghong Wang, Qinghua Zhao, Rong Luo, Mingzhao Xiao, Mingjun Zhang, Weibo Xie
Prevalence And Risk Factors For Helicobacter Pylori Infection In Southwest China: A Study Of Health Examination Participants Based On 13c-Urea Breath Test, Jie Liu, Yonghong Wang, Qinghua Zhao, Rong Luo, Mingzhao Xiao, Mingjun Zhang, Weibo Xie
Turkish Journal of Medical Sciences
Background/aim: Helicobacter pylori (H. pylori) has a high prevalence in developing countries. We aimed to investigate the current prevalence of H. pylori, as well as its potential serum risk factors, in a population from southwest China.Materials and methods: This cross-sectional study included 10,912 subjects who received medical examinations at the First Affiliated Hospital of Chongqing Medical University in 2014. Data regarding physical examinations and biochemical measurements were collected, and H. pylori infection was diagnosed with a 13C-urea breath test. Logistic regression was conducted to identify the risk factors for H. pylori infection.Results: The infection rate of H. pylori was 34.4% …
Detection And Molecular Characterisation Of Adenovirus In Children Under 5 Years Old With Diarrhoea, Meryem Çolak, Gülendam Bozdayi, Ayli̇n Altay, Zahi̇de Yalaki̇, Kamruddi̇n Ahmed, Seçi̇l Özkan
Detection And Molecular Characterisation Of Adenovirus In Children Under 5 Years Old With Diarrhoea, Meryem Çolak, Gülendam Bozdayi, Ayli̇n Altay, Zahi̇de Yalaki̇, Kamruddi̇n Ahmed, Seçi̇l Özkan
Turkish Journal of Medical Sciences
Background/aim: To determine the frequency, genotype distribution, and genetic relatedness of adenoviruses in children under 5 years old with diarrhoea and to investigate their distribution according to clinical findings, age, months, and seasons. Materials and methods: Stool samples were collected from 180 children with acute gastroenteritis who presented from July 2007 through June 2011 at the Ankara Training and Education Hospital. Stool samples were analysed by immune chromatographic test (ICT), enzyme immunoassay (EIA), and polymerase chain reaction (PCR). All adenovirus types were determined by nucleotide sequence analysis. A phylogenetic tree was constructed by Mega 6.0 using the neighbour-joining method. Results: …
Patients' Attitudes And Knowledge About Drug Use: A Survey In Turkish Family Healthcare Centres And State Hospitals, Ahmet Akici, Sali̇h Mollahali̇loğlu, Başak Dönertaş, Şenay Özgülcü, Ali̇ Alkan, Nesri̇n Fi̇li̇z Başaran
Patients' Attitudes And Knowledge About Drug Use: A Survey In Turkish Family Healthcare Centres And State Hospitals, Ahmet Akici, Sali̇h Mollahali̇loğlu, Başak Dönertaş, Şenay Özgülcü, Ali̇ Alkan, Nesri̇n Fi̇li̇z Başaran
Turkish Journal of Medical Sciences
Background/aim: Irrational drug use is a common problem. This study aimed to evaluate patients' knowledge and habits concerning drug use, and compare them in terms of some sociodemographic characteristics. Materials and methods: A face-to-face questionnaire was given to outpatients from family healthcare centres (FHCs) and state hospitals (SHs) in 12 provinces in Turkey during May 2010. A total of 4470 patients (FHCs: 2209; SHs: 2261) responded to the questionnaire (response rate: 93.1%). Results: Getting prescriptions without a physical examination was common (second place in FHCs; third place in SHs); 51.0% stated that they wanted physicians to prescribe drugs that they …
Effects Of Whole Blood Viscosity And Plasma Nox On Cardiac Function And Cerebral Blood Flow In Children With Chronic Kidney Disease, Necla Buyan, Meltem Akçaboy, Tayfun Göktaş, Serdar Kula, Bi̇jen Nazliel, Ni̇lgün Çakar, Nermi̇n Uncu, Bülent Çeli̇k, Deni̇z Erbaş
Effects Of Whole Blood Viscosity And Plasma Nox On Cardiac Function And Cerebral Blood Flow In Children With Chronic Kidney Disease, Necla Buyan, Meltem Akçaboy, Tayfun Göktaş, Serdar Kula, Bi̇jen Nazliel, Ni̇lgün Çakar, Nermi̇n Uncu, Bülent Çeli̇k, Deni̇z Erbaş
Turkish Journal of Medical Sciences
Background/aim: The aim of the study was to investigate the effects of whole blood viscosity and plasma nitric oxide on cerebral and cardiovascular risks associated with chronic kidney disease. Materials and methods: The study group consisted of 40 pediatric patients and 21 healthy control subjects. Hematologic and biochemical variables, viscosity and plasma nitric oxide levels, echocardiographic findings, and middle cerebral artery blood flow velocity were examined. Results: Viscosity values of patients were significantly lower than those of the control group. Lower values of hematocrit, total protein, and albumin and higher values of ferritin in all patient groups resulted in significantly …
Multiplex Pcr Detection Of Problematic Pathogens Of Clinically Heterogeneous Bacterial Vaginosis In Bulgarian Women, Konstantsa Tosheva-Daskalova, Tanya Vasileva Strateva, Ivan Gergov Mitov, Raina Tzvetanova Gergova
Multiplex Pcr Detection Of Problematic Pathogens Of Clinically Heterogeneous Bacterial Vaginosis In Bulgarian Women, Konstantsa Tosheva-Daskalova, Tanya Vasileva Strateva, Ivan Gergov Mitov, Raina Tzvetanova Gergova
Turkish Journal of Medical Sciences
Background/aim: This study aimed to investigate the correlation between the prevalence of problematic pathogens and the clinical status of women with bacterial vaginosis (BV). Materials and methods: Gardnerella vaginalis, Atopobium vaginae, and Mobiluncus spp. were detected using a multiplex PCR assay, and their role in the infection of Bulgarian women with clinically heterogeneous BV was evaluated. Results: The predominant BV-associated pathogen identified was G. vaginalis with an incidence of 98.39%, followed by A. vaginae (68.05%) and Mobiluncus spp. at 17.01%. The coexistence of A. vaginae and G. vaginalis was more common in women with discharge (in 72.04%) and in patients …
Analysis Of Recurrent Urethral Strictures Due To Iatrogenic Urethral Trauma, Fuat Kizilay, Adnan Şi̇mşi̇r, Mehmet Ceyhun Özyurt
Analysis Of Recurrent Urethral Strictures Due To Iatrogenic Urethral Trauma, Fuat Kizilay, Adnan Şi̇mşi̇r, Mehmet Ceyhun Özyurt
Turkish Journal of Medical Sciences
Background/aim: We aimed to analyze the effects of stricture location, etiology, age, and catheterization time on recurrence rate and recurrence time in patients who underwent direct vision internal urethrotomy (DVIU) for urethral strictures. Materials and methods: Patients were divided into three groups according to the location of the stricture: penile urethra, membranous urethra, and prostatic urethra strictures. Patients were also divided into three groups according to etiologic factors: strictures secondary to endoscopic procedures, urethral catheterization, and open or radical prostatectomy (anastomotic strictures were included in this group). Patients were also divided into three groups according to catheterization time: 5-7 days. …
Epidemiology And Analysis Of Invasive Fungal Infections In Patients Withhematological Malignancies: A Single-Center Real-Life Experience, Nur Soyer, Hati̇ce Demet Ki̇per Ünal, Fi̇li̇z Vural, Fahri̇ Şahi̇n, Mahmut Töbü, Ayhan Dönmez, Murat Tombuloğlu, Bi̇lgi̇n Arda, Güray Saydam
Epidemiology And Analysis Of Invasive Fungal Infections In Patients Withhematological Malignancies: A Single-Center Real-Life Experience, Nur Soyer, Hati̇ce Demet Ki̇per Ünal, Fi̇li̇z Vural, Fahri̇ Şahi̇n, Mahmut Töbü, Ayhan Dönmez, Murat Tombuloğlu, Bi̇lgi̇n Arda, Güray Saydam
Turkish Journal of Medical Sciences
Background/aim: Invasive fungal infection (IFI) causes morbidity and mortality among patients with hematological malignancies. We evaluated the incidence and treatment characteristics of IFIs between October 2012 and December 2013. Materials and methods: Patients who received chemotherapy or stem cell transplantation were retrospectively evaluated. Fungal infections were classified according to EORTC criteria.Results: Prophylaxis and antifungal therapy were given in 30.5% and 23.6% of 522 chemotherapy courses, respectively. The incidence of proven/probable IFI was 6.7%. The incidence of IFI among patients who received prophylaxis was significantly higher than among those who did not receive it (11.3% vs. 4.6%, P = 0.005). There …