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Full-Text Articles in Medicine and Health Sciences

Development Of Spermatogonial Stem Cell Niche And Immunoexpression Of Vimentin Filaments In The Testes Of Prenatal And Postnatal Indian Buffalo (Bubalus Bubalis), Ashritha Quanisha Carlo, Devendra Pathak, Opinder Singh, Neelam Bansal Jan 2019

Development Of Spermatogonial Stem Cell Niche And Immunoexpression Of Vimentin Filaments In The Testes Of Prenatal And Postnatal Indian Buffalo (Bubalus Bubalis), Ashritha Quanisha Carlo, Devendra Pathak, Opinder Singh, Neelam Bansal

Turkish Journal of Veterinary & Animal Sciences

In this study, we established the components of the buffalo spermatogonial stem cell (SSC) niche in prenatal (38.5-280 days of gestation), neonatal, prepubertal, and adult testes histochemically and immunohistochemically. Immunohistochemically, the changes in vimentin expression were evaluated. During prenatal life, the niche of primordial germ cells was formed by the surrounding mesenchymal cells and fibroblasts. The basement membrane (BM) was not organized at this stage. At 7.6 cm crown-rump length, testicular cords with a thin BM were seen. At the late gestational period, testicular cords with well-organized BM were seen. At the neonatal stage, the testicular cords were lined with …


Risk And Protective Factors Associated With Gastrointestinal Parasites Of Dogs From An Urban Area Of Córdoba, Argentina, Carlos Eugenio Motta, Maria Romina Rivero, Carlos Daniel De Angelo, Ana María Sbaffo, Karina Ivana Tiranti Jan 2019

Risk And Protective Factors Associated With Gastrointestinal Parasites Of Dogs From An Urban Area Of Córdoba, Argentina, Carlos Eugenio Motta, Maria Romina Rivero, Carlos Daniel De Angelo, Ana María Sbaffo, Karina Ivana Tiranti

Turkish Journal of Veterinary & Animal Sciences

Prevalence of gastrointestinal (GI) parasites and the effect of associated factors were evaluated in household dogs from an urban area of Córdoba, Argentina. A total of 493 fecal samples were collected during 2010 and 2013 and processed with Willis` salt, Sheathers sugar flotation, and formol-ether concentration techniques. Overall prevalence of GI parasites was 45.23% (95% CI 40.83-49.62), and Ancylostoma caninum (30.83%) was the most frequent parasite, followed by Trichuris vulpis (9.94%), Cystoisospora spp. (7.71%), Toxocara canis (6.90%), and Giardia spp. (5.88%). Independent variables were presence of at least one parasite element, named "all parasites", and each GI parasite more frequently …


Genotyping Of Prolactin, Kappa Casein, And Pituitary Transcription Factor 1 Genes Of The Anatolian Water Buffalo Population In The Kızılırmak Delta, Emi̇ne Toparslan, Levent Mercan Jan 2019

Genotyping Of Prolactin, Kappa Casein, And Pituitary Transcription Factor 1 Genes Of The Anatolian Water Buffalo Population In The Kızılırmak Delta, Emi̇ne Toparslan, Levent Mercan

Turkish Journal of Veterinary & Animal Sciences

Thirty-five Anatolian water buffalo were selected from among a total of almost 7000 animals from 11 herds in the Kızılırmak Delta, which is known to be one of the most important areas for water buffalo farming in Turkey. The cleaved amplified polymorphic sequences (CAPS) method was used to identify single-nucleotide polymorphisms at 3 loci that are associated with milk production, namely PRL, CSN3, and PIT-1, which are associated with milk processing and milk yields, respectively. Sequence-tagged sites of PRL, CSN3, and PIT-1 were digested by restriction endonucleases RsaI, HindIII, and HinfI, respectively. Capillary electrophoretic analysis identified all samples as belonging …


Study Of Retail Egg Supply Chain For Quality In Relation To Level Of Sanitization Andfarm Of Origin, Vinayananda Chilur Omkarappa, Mohamed Nadeem Fairoze, Madhavaprasad Chakkodabail Benakabhat, Kaustubh Bhave, Nagappa Karabasanavar Jan 2019

Study Of Retail Egg Supply Chain For Quality In Relation To Level Of Sanitization Andfarm Of Origin, Vinayananda Chilur Omkarappa, Mohamed Nadeem Fairoze, Madhavaprasad Chakkodabail Benakabhat, Kaustubh Bhave, Nagappa Karabasanavar

Turkish Journal of Veterinary & Animal Sciences

In the present cross-sectional study, eggs collected from retail outlets were analyzed for physicochemical and microbial quality. Comparisons were made between ?sanitized? (cleaned, sanitized, and retailed after packaging) and ?unsanitized? (not subjected to cleaning, sanitization, and packaging) retail table eggs that originated from ?commercial? and ?backyard? (eggs retailed loose without any cleaning, sanitization, or packaging) farms. A total of 1120 eggs collected from retail markets were analyzed for physicochemical (weight, shell thickness, shape, yolk index, albumen index, Haugh unit, color, and pH) and microbial (total viable count, and yeast and mold counts) characteristics. Eggs collected from retail markets were found …


Phenotypic Characterization And Differentiation Of Mesenchymal Stem Cells Originating From Adipose Tissue, Ece Çerçi̇, Hati̇ce Erdost Jan 2019

Phenotypic Characterization And Differentiation Of Mesenchymal Stem Cells Originating From Adipose Tissue, Ece Çerçi̇, Hati̇ce Erdost

Turkish Journal of Veterinary & Animal Sciences

Stem cells are known as undifferentiated cells that are capable of divisions and self-renewal over an extended period. Adipose tissue-derived mesenchymal stem cells (ADSCs) are known to differentiate into many different organ and tissue cells. The purpose of this study was to characterize adipose tissue-derived mesenchymal stem cells in detail based on the expression status of certain surface markers and differentiation stages for clinical and laboratory applications. The migrating phase and mitotic property of the cells from adipose tissue were assessed under a microscope. Cell counting was performed during the first, second, and third passages. The cells were differentiated into …


Animal Remains Of Alaybeyi Höyük, Abu Bakar Siddiq Jan 2019

Animal Remains Of Alaybeyi Höyük, Abu Bakar Siddiq

Turkish Journal of Veterinary & Animal Sciences

This paper presents the zooarchaeological observations on animal remains of Alaybeyi Höyük unearthed from 2016 and 2017 excavation sessions. Dated to 4721-4553 cal. BC, Alaybeyi stands so far as the oldest archaeological settlement discovered in northeast Anatolia. Therefore, the faunal assemblage at Alaybeyi offers great opportunity to study the status of animals and their relationships with humans in the largely unexplored Kars-Erzurum plateau covering a period from the Chalcolithic to Late Iron Age. Taxonomic and osteometric analyses show that, like the present day, cattle were dominant over caprines, revealing extensive cattle pastoralism in the region for at least about 7 …


A Diagnostic Survey Of Neospora Caninum Infection In Aborted Fetuses In The Middle Black Sea Region And Sivas Province, Turkey, Mustafa Açici, Cenk Soner Bölükbaş, Gökmen Zafer Pekmezci̇, Hande Gürler, Oktay Genç, Ali̇ Tümay Gürler, Selma Kaya, Şi̇nasi̇ Umur Jan 2019

A Diagnostic Survey Of Neospora Caninum Infection In Aborted Fetuses In The Middle Black Sea Region And Sivas Province, Turkey, Mustafa Açici, Cenk Soner Bölükbaş, Gökmen Zafer Pekmezci̇, Hande Gürler, Oktay Genç, Ali̇ Tümay Gürler, Selma Kaya, Şi̇nasi̇ Umur

Turkish Journal of Veterinary & Animal Sciences

Neospora caninum is a major, cosmopolitan, protozoan parasite associated with abortion in cattle and water buffaloes. In this study, real-time PCR was used for the detection and quantification of the burden of N. caninum infections in aborted fetuses in the Middle Black Sea Region and Sivas Province of Turkey. In total, N. caninum DNA was detected in 44 of the 89 (49.4%) aborted fetuses of the cattle and water buffalo from 89 different farms. The authors conclude that the pervasiveness of neosporosis is a threat to cattle breeding in the Middle Black Sea Region and Sivas Province. Real-time PCR testing …


Effect Of Spermvital® Technology On Conception Rate In Repeat Breeder Multiparous Dairy Cows: Preliminary Results, Alper Koçyi̇ği̇t, Bariş Atalay Uslu, Sai̇t Şendağ, Eli̇sabeth Treupel, Axel Wehrend Jan 2019

Effect Of Spermvital® Technology On Conception Rate In Repeat Breeder Multiparous Dairy Cows: Preliminary Results, Alper Koçyi̇ği̇t, Bariş Atalay Uslu, Sai̇t Şendağ, Eli̇sabeth Treupel, Axel Wehrend

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to investigate the effect of SV technology on conception rates in repeat breeder multiparous dairy cows. Seventy-nine multiparous Holstein cows from a private dairy farm were used in the study. These animals were cows that had failed to conceive from at least 3 regularly spaced services (repeat breeders). Estrus cycles of the cows were synchronized by 2 injections of the PG analogue, administered 11 days apart. GnRH was applied 48 h after the second injection of PG. Twenty-four h after this administration, the animals were randomly divided into 2 groups, control and SV. The …


The Effect Of Tannin Extract And N-3 Fatty Acid Source On Nutrient Digestibility, Blood Metabolites, Enzyme Activity, And Ruminal Parameters Of Lactating Ewes, Roghayeh Valizadeh Yonjalli, Farzad Mirzaei Aghjehgheshlagh, Ali Mahdavi, Bahman Navidshad, Hamid Staji Jan 2019

The Effect Of Tannin Extract And N-3 Fatty Acid Source On Nutrient Digestibility, Blood Metabolites, Enzyme Activity, And Ruminal Parameters Of Lactating Ewes, Roghayeh Valizadeh Yonjalli, Farzad Mirzaei Aghjehgheshlagh, Ali Mahdavi, Bahman Navidshad, Hamid Staji

Turkish Journal of Veterinary & Animal Sciences

This study aimed to evaluate the effects of tannin extract and n-3 fatty acid supplementation on nutrient digestibility, ruminal parameters, blood metabolites, and enzyme activity in lactating ewes. Thirty-six lactating ewes were allocated to 6 experimental groups. The dietary treatments were as follows: 1) control, 2) diet supplemented with 2% dry matter (DM) oak leaf tannin extract, 3) diet supplemented with 2% DM grape pomace tannin extract, 4) diet supplemented with 2% DM linseed oil, 5) diet supplemented with 2% DM oak leaf tannin extract and 2% DM linseed oil, and 6) diet supplemented with 2% DM grape pomace tannin …


On-Farm Diagnosis Of Latent Respiratory Failure In Calves, Anton Chernitskiy, Sergey Shabunin, Tatiana Kuchmenko, Vladimir Safonov Jan 2019

On-Farm Diagnosis Of Latent Respiratory Failure In Calves, Anton Chernitskiy, Sergey Shabunin, Tatiana Kuchmenko, Vladimir Safonov

Turkish Journal of Veterinary & Animal Sciences

The goal of this study was to develop a method for the diagnosis of latent respiratory failure in calves with bovine respiratory disease (BRD) in farm conditions. The study involved 48 calves of the red-motley Holstein breed aged 14-28 days, with no previously experienced BRD, no dyspnea at rest, and a lack of anemia. Group I consisted of 24 calves with spontaneous or induced cough and WI clinical score of ≥5. Group II included 24 calves without spontaneous and induced cough and WI clinical score of ≤3. The determination of respiratory rate (RR), respiratory minute volume, and tidal volume in …


Effects Of Supplementary Nano-Zno On In Vitro Ruminal Fermentation, Methane Release, Antioxidants, And Microbial Biomass, Hassan Riazi, Javad Rezaei, Yousef Rouzbehan Jan 2019

Effects Of Supplementary Nano-Zno On In Vitro Ruminal Fermentation, Methane Release, Antioxidants, And Microbial Biomass, Hassan Riazi, Javad Rezaei, Yousef Rouzbehan

Turkish Journal of Veterinary & Animal Sciences

The effects of nano-ZnO on in vitro ruminal fermentation, methane release, total antioxidant capacity (TAC), and microbial biomass production (MBP) were assessed using an in vitro gas production technique. Treatments included a control diet and diets containing 20, 40, or 60 mg of supplemental Zn per kg dry matter (DM) as ZnO or nano-ZnO. As a result of this study, supplementation of 20 mg of Zn as nano-ZnO, similar to ZnO, decreased methane production and protozoa enumeration but improved (P < 0.05) TAC, MBP, digestibility and truly degraded substrate (TDS). As compared with the control treatment, adding the supplementary Zn had no effect on partitioning factor, MBP efficiency, pH, and ammonia-N (P > 0.05). The diets containing 40 and 60 mg of supplementary Zn, as nano-ZnO or ZnO, had no advantage over the …


The Comparing Of Homogenization Methods For Oxidative And Antioxidative Analyses Of Sperm, Ömer Varişli, Numan Akyol Jan 2019

The Comparing Of Homogenization Methods For Oxidative And Antioxidative Analyses Of Sperm, Ömer Varişli, Numan Akyol

Turkish Journal of Veterinary & Animal Sciences

Pretreatment of sperm for oxidative and antioxidative analysis has been shown to be different in studies. These differences can affect the result of analyses. The aim of this study was to compare the analyses of sperm homogenization methods. The semen of four rams were used in the study. Pretreatment procedures included the rotary, bead, and ultrasonic homogenization methods. Oxidative and antioxidative status of sperm samples was assessed by measuring serum lipid hydroperoxide, total oxidant status, free sulfhydryl groups (SH total thiol), ceruloplasmin, and total antioxidant capacity levels. As a result, the homogenization methods before oxidative and antioxidative status analyses significantly …


Effect Of Exercise On Some Minerals, Metabolites And Enzyme Activities In The Serum Of Trained Arabian Horses, Roya Pourmohammad, Mehrdad Mohri, Hesam Seifi, Kamran Sardari Jan 2019

Effect Of Exercise On Some Minerals, Metabolites And Enzyme Activities In The Serum Of Trained Arabian Horses, Roya Pourmohammad, Mehrdad Mohri, Hesam Seifi, Kamran Sardari

Turkish Journal of Veterinary & Animal Sciences

The exercise-induced variations of some biochemical parameters including calcium (Ca), phosphorous (P), iron (Fe), copper (Cu), manganese (Mn), selenium (Se), zinc (Zn), sodium (Na), potassium (K), chlorine (Cl), glucose, urea, creatinine, lactate dehydrogenase (LDH), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatine kinase (CK) were assessed in the serum of 25 Arabian horses. Blood samples were taken from the jugular vein 3 different times: before exercise, 5 h after exercise, and 18 h after exercise. Statistical analysis was performed using SAS (version 9.2; SAS Institute, Cary, NC, USA). Ca, Cl, glucose, and urea showed significant (P < 0.05) changes due to exercise. There was significant increase from before exercise to 5 h after exercise in urea concentrations while Ca and Cl concentrations significantly decreased. A significant ascending trend for Ca between 5 h and 18 h after exercise was also seen, while glucose and urea had a significantly descending trend. No significant time-based variations were observed for other variables. The results of the present study indicated that exercise could affect the value of some biochemical parameters, which could be used in future studies evaluating the health status of Arabian horses.


Current Perspectives For The Treatment Of Chronic Myeloid Leukemia, Eli̇fcan Aladağ Karakulak, İbrahi̇m Celaletti̇n Haznedaroğlu Jan 2019

Current Perspectives For The Treatment Of Chronic Myeloid Leukemia, Eli̇fcan Aladağ Karakulak, İbrahi̇m Celaletti̇n Haznedaroğlu

Turkish Journal of Medical Sciences

With an annual incidence of 1-2 in a million, Ph*(+) chronic myeloid leukemia (CML) is a clonal hematopoietic stem cell disease that makes myeloid neoplastic cells breed out of control. This BCR-ABL(+) myeloproliferative disease makes up about 15%-20% of all leukemia cases in adults. CML is seen more in males than females, with a rate of three to two. However, it does not show differences in prevalence in terms of age. CML consists of three clinical phases. The first one is the chronic phase, defined by rising white blood cell levels and also by myeloid proliferation and bone marrow maturation. …


A Prospective Clinical Investigation Of The Effects Of Anti-Tnf Alpha Therapy On Exercise Capacity In Patients With Ankylosing Spondylitis, Erhan Çapkin, Seyhan Bi̇lge Keski̇n, Murat Karkucak, Ahmet Ayar Jan 2019

A Prospective Clinical Investigation Of The Effects Of Anti-Tnf Alpha Therapy On Exercise Capacity In Patients With Ankylosing Spondylitis, Erhan Çapkin, Seyhan Bi̇lge Keski̇n, Murat Karkucak, Ahmet Ayar

Turkish Journal of Medical Sciences

The purpose of this study was to investigate possible effects of anti-TNF alpha therapy on cardiorespiratory fitness and physical functional capacity of patients with ankylosing spondylitis (AS). Materials and methods: Twenty-eight AS patients meeting the modified New York criteria with active disease state and an equivalent number of healthy individuals as the control were prospectively enrolled. Physical working capacity and aerobic exercise capacity of the participants were determined by using cardiopulmonary exercise tests, performed before and 4 months after initiation of anti-TNF alpha therapy. Results: The mean age of the patients was 37 ± 9.1 years, and mean duration of …


Comparison Of Early And Long Term Outcomes Of Open Lichtenstein Repair And Totally Extraperitoneal Herniorrhaphy For Primary Inguinal Hernias, Bariş Sevi̇nç, Nurullah Damburaci, Murat Güner, Ömer Karahan Jan 2019

Comparison Of Early And Long Term Outcomes Of Open Lichtenstein Repair And Totally Extraperitoneal Herniorrhaphy For Primary Inguinal Hernias, Bariş Sevi̇nç, Nurullah Damburaci, Murat Güner, Ömer Karahan

Turkish Journal of Medical Sciences

Inguinal hernia repair is one of the most common surgical procedures worldwide. There is still controversy over which method has the best postoperative results. The aim of this study was to compare early and late postoperative results of laparoscopic totally extraperitoneal herniorrhaphy (TEP) and open Lichtenstein herniorrhaphy (OLR). Materials and methods: The study was conducted in a randomized prospective manner and it was concluded with 302 patients (147 cases in TEP group and 155 cases in OLR group). All procedures were performed by two experienced surgeons in both open and laparoscopic inguinal hernia repair.Results: The groups were similar in terms …


The Effects Of Uterine Size With Or Without Abdominal Obesity On Spinal Block Level And Vasopressor Requirement In Elective Cesarean Section: A Prospective Observational Study, İlkben Günüşen, Asuman Sargin, Ali̇ Akdemi̇r, Ahmet Mete Ergenoğlu Jan 2019

The Effects Of Uterine Size With Or Without Abdominal Obesity On Spinal Block Level And Vasopressor Requirement In Elective Cesarean Section: A Prospective Observational Study, İlkben Günüşen, Asuman Sargin, Ali̇ Akdemi̇r, Ahmet Mete Ergenoğlu

Turkish Journal of Medical Sciences

Hypotension is a serious complication caused by spinal anesthesia that places both the mother and fetus at increased risk. We aimed to investigate the effects of uterine size with or without abdominal obesity on sensory block level of pregnant women receiving spinal anesthesia. Materials and methods: This study included 125 term parturients who underwent cesarean section. Motor and sensory block characteristics, the distance between the symphysis pubis and the fundus (SPF), the distance between the symphysis pubis and the xiphoid (SPX), newborn and placental weights, adverse effects, and doses of ephedrine were recorded. Results: Sensory block level and ephedrine dose …


Fatigue And Sleep In Children And Adolescents With Juvenile Idiopathic Arthritis:A Cross-Sectional Study, Ela Tarakci, Sai̇me Ni̇lay Arman, Kenan Barut, Sezgi̇n Şahi̇n, Amra Adrovi̇ç, Özgür Kasapçopur Jan 2019

Fatigue And Sleep In Children And Adolescents With Juvenile Idiopathic Arthritis:A Cross-Sectional Study, Ela Tarakci, Sai̇me Ni̇lay Arman, Kenan Barut, Sezgi̇n Şahi̇n, Amra Adrovi̇ç, Özgür Kasapçopur

Turkish Journal of Medical Sciences

The aims of this study were to primarily investigate fatigue and sleep and to secondarily examine possible relationships between disease activity, pain, and functional ability in children and adolescents with juvenile idiopathic arthritis (JIA). Materials and methods: Ninety-six patients were enrolled in the study. Disease activity, functional ability, fatigue symptoms, fatigue severity, and sleep quality were assessed with the Juvenile Arthritis Disease Activity Score (JADAS), Childhood Health Assessment Questionnaire (CHAQ), Pediatric Quality of Life Inventory-Multidimensional Fatigue Scale (PedsQL-F), visual analog scale (VAS), and Pittsburgh Sleep Quality Index (PSQI), respectively. Results: Fatigue severity was moderate to high in 75% of patients …


Serum Endocan Level And Diastolic Functions In The Case Of Lead Exposure, Hali̇l Kara, Uğur Nadi̇r Karakulak, Meşi̇de Gündüzöz, Ceylan Bal, Murat Alişik, Murat Büyükşekerci̇, Servet Bi̇rgi̇n İri̇taş, Ömer Hinç Yilmaz, Lütfi̇ye Tutkun Jan 2019

Serum Endocan Level And Diastolic Functions In The Case Of Lead Exposure, Hali̇l Kara, Uğur Nadi̇r Karakulak, Meşi̇de Gündüzöz, Ceylan Bal, Murat Alişik, Murat Büyükşekerci̇, Servet Bi̇rgi̇n İri̇taş, Ömer Hinç Yilmaz, Lütfi̇ye Tutkun

Turkish Journal of Medical Sciences

Lead can cause morphological and functional changes in heart, and inflammation and endothelial dysfunction in vasculature. Endocan, as a novel indicator of endothelial dysfunction, has been used for cardiovascular diseases. This study investigated the relationship between lead exposure, endocan levels, and diastolic functions.Materials and methods: A total of 51 lead-exposed workers without a known cardiovascular disease or risk factors and 54 healthy controls were enrolled. All participants underwent transthoracic echocardiography. Blood lead and serum endocan levels were analyzed.Results: Baseline demographic and clinical characteristics were found to be similar between groups. Median blood lead (32 vs 1.5 µg/dL, P < 0.001) and serum endocan levels (67 vs 57.1 pg/mL, P = 0.02) were significantly higher in the lead-exposed group. Serum endocan level showed a positive correlation with blood lead levels (r = 0.404, P = 0.003) in lead-exposed workers. Serum endocan level was an independent risk factor for increased E/E' ratio (ß = 0.704, P = 0.002) and left atrial volume index (ß = 1.158, P = 0.011) and higher level of lead in blood was an independent risk factor for increased E wave (ß = 8.004, P = 0.022) in lead-exposed workers. Conclusion: Worsened diastolic functions may be seen in the course of lead exposure. Due to sharing a similar mechanism, a higher serum level of endocan may be a valuable laboratory clue for impaired diastolic function in this population.


Ischemic Modified Albumin As A New Biomarker In Predicting Oxidative Stress In Alopecia Areata, Hati̇ce Ataş, Müzeyyen Gönül, Yasi̇n Öztürk, Mustafa Kavutçu Jan 2019

Ischemic Modified Albumin As A New Biomarker In Predicting Oxidative Stress In Alopecia Areata, Hati̇ce Ataş, Müzeyyen Gönül, Yasi̇n Öztürk, Mustafa Kavutçu

Turkish Journal of Medical Sciences

Results show that oxidative stress is a pathophysiologic factor for alopecia areata (AA); however, the markers used can be confounding. Thus, we aimed to investigate the role of oxidative stress in the pathogenesis of AA through an evaluation of ischemia-modified albumin (IMA); other markers of the oxidant/antioxidant system, such as SOD, CAT, GSH-ST, and MDA; and contributing clinical risk factors. Materials and methods: The usefulness of IMA as a new marker for oxidative stress was compared with that of other markers and evaluated in patients with AA.Results: The mean serum level of IMA was of higher statistical significance in AA …


Relationship Between Plasma Ykl-40 Levels And Endothelial Dysfunction In Chronic Kidney Disease, Gül Sema Yildiran Keski̇n, Özant Helvaci, Çağri Yayla, Özge Tuğçe Paşaoğlu, Çağlar Keski̇n, Seli̇m Turgay Arinsoy, Ülver Deri̇ci̇ Jan 2019

Relationship Between Plasma Ykl-40 Levels And Endothelial Dysfunction In Chronic Kidney Disease, Gül Sema Yildiran Keski̇n, Özant Helvaci, Çağri Yayla, Özge Tuğçe Paşaoğlu, Çağlar Keski̇n, Seli̇m Turgay Arinsoy, Ülver Deri̇ci̇

Turkish Journal of Medical Sciences

We aimed to evaluate the relationship between YKL-40 and endothelial dysfunction in chronic kidney disease. Materials and methods: Twenty-nine hemodialysis patients, 101 patients with nondialytic (stage 2, 3, 4, and 5 ND) chronic kidney disease (CKD), and 38 healthy individuals as a control group were included. YKL-40 levels were measured by ELISA. Endothelial dysfunction was indirectly measured by flow-mediated dilatation percentage (FMD) in the brachial artery. Results: YKL-40 levels were higher in CKD patients than controls and highest in HD patients (P = 0.001). FMD values were lower in nondialytic CKD patients and lowest in HD patients (P = 0.001). …


Comparison Of Reference Systems In The Assessment Of Age-Related Serum Immunoglobulin Levels In Pediatric Patients, İlknur Külhaş Çeli̇k, Ersoy Ci̇velek, Ayşe Meti̇n, Tayfur Gi̇ni̇ş, Müge Toyran, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş Jan 2019

Comparison Of Reference Systems In The Assessment Of Age-Related Serum Immunoglobulin Levels In Pediatric Patients, İlknur Külhaş Çeli̇k, Ersoy Ci̇velek, Ayşe Meti̇n, Tayfur Gi̇ni̇ş, Müge Toyran, Emi̇ne Di̇bek Misirlioğlu, Can Naci̇ Kocabaş

Turkish Journal of Medical Sciences

Ig level assessment is frequently used in the diagnosis and follow-up of immunodeficiency, as well as in studies investigating the prevalence of low serum Ig level in specific diseases.Material and methods: Patients who underwent Ig testing in the inpatient and outpatient clinics of our hospital in the years 2010-2016 were included. The Ig levels of the patients were assessed separately according to two reference systems commonly used in Turkey and another reference system used in the USA.Results: A total of 20,138 patients (57.6% male) were included in the study. The median age of the patients was 55.7 months (interquartile range: …


8-Armed Octopus: Evaluation Of Clinicopathologic Prognostic Factors Of Urothelial Carcinoma Of The Upper Urinary System, Sümeyye Ekmekci̇, Ülkü Küçük, Yelda Dere, İzzeti̇ye Ebru Çakir, Hati̇ce Ceren Sayar, Batuhan Ergani̇, Özgür Çakmak, Ozan Bozkurt, Kutsal Yörükoğlu Jan 2019

8-Armed Octopus: Evaluation Of Clinicopathologic Prognostic Factors Of Urothelial Carcinoma Of The Upper Urinary System, Sümeyye Ekmekci̇, Ülkü Küçük, Yelda Dere, İzzeti̇ye Ebru Çakir, Hati̇ce Ceren Sayar, Batuhan Ergani̇, Özgür Çakmak, Ozan Bozkurt, Kutsal Yörükoğlu

Turkish Journal of Medical Sciences

This study was designed to determine the characteristic features of upper urinary system urothelial carcinomas (UUSUCs) and to evaluate the clinicopathological parameters associated with prognosis.Materials and methods: A total of 74 cases of UUSUC were included, from three different centers. Demographic data and histopathological features such as tumor localization, concomitant tumor in the urinary system, distant metastasis with overall survival and disease-free survival obtained from the hospital records were evaluated retrospectively. Histopathologic prognostic features such as grade, perineural invasion, lymphovascular invasion, tumor necrosis, and surgical margin status were also evaluated.Results: Seventy cases (94.6%) underwent open nephroureterectomy whereas 4 cases (5.4%) …


Reliability And Validity Of The Turkish Version Of The Physical Activity Questionnaire For Older Children (Paq-C), Leyla Erdi̇m, Ayşe Ergün, Sema Kuğuoğlu Jan 2019

Reliability And Validity Of The Turkish Version Of The Physical Activity Questionnaire For Older Children (Paq-C), Leyla Erdi̇m, Ayşe Ergün, Sema Kuğuoğlu

Turkish Journal of Medical Sciences

The Physical Activity Questionnaire for Older Children (PAQ-C) is one of the most frequently used questionnaires for evaluating moderate to vigorous levels of physical activity in children. However, a Turkish version of the questionnaire was not available. This study aimed to create a Turkish version of the PAQ-C and examine its psychometric characteristics and factor structure.Materials and methods: The study was conducted with 784 primary school students (ages 9-14 years). The PAQ-C was examined for content and construct validity and analyzed in terms of reliability. Content validity was evaluated with the content validity index (CVI), construct validity, exploratory factor analysis …


Validity And Reliability Of The Amsterdam Preoperative Anxiety And Information Scale In The Turkish Population, Funda Çeti̇nkaya, Esi̇n Kavuran, Kevser Sevgi̇ Ünal Aslan Jan 2019

Validity And Reliability Of The Amsterdam Preoperative Anxiety And Information Scale In The Turkish Population, Funda Çeti̇nkaya, Esi̇n Kavuran, Kevser Sevgi̇ Ünal Aslan

Turkish Journal of Medical Sciences

This study aimed to adapt the Amsterdam Preoperative Anxiety and Information Scale (APAIS) to measure the preoperative anxiety of adult Turkish patients undergoing surgery.Materials and methods: The sample of this methodological study included 210 patients. Data were collected by using personal information forms, the APAIS, and the State Anxiety Scale (STAI). Cronbach's ∝-coefficient was calculated, and test-retest reliability was tested. Results: Cronbach's ∝-coefficients of the APAIS anxiety and information requirement subscales were 0.897 and 0.786, respectively. The mean test and retest scores of the APAIS were not different. The test and retest scores of the patients were significantly, positively, and …


Iron Supplementation Should Be Given In Breath-Holding Spells Regardless Of Anemia, Gürkan Gürbüz, Peren Perk Yücel, Turgay Çokyaman, Özge Berfu Gürbüz Jan 2019

Iron Supplementation Should Be Given In Breath-Holding Spells Regardless Of Anemia, Gürkan Gürbüz, Peren Perk Yücel, Turgay Çokyaman, Özge Berfu Gürbüz

Turkish Journal of Medical Sciences

The purpose of this retrospective study was to determine the effectiveness of oral iron therapy in breath-holding spells and evaluation of electrocardiographical changes.Materials and methods: Three hundred twelve children aged 1-48 months and diagnosed with breath-holding spells between January 2017 and April 2018 were included. Patients' laboratory findings were compared with 100 patients who had one simple febrile seizure.Results: Cyanotic breath-holding spells were diagnosed in 85.3% (n = 266) of patients, pallid spells in 5.1% (n = 16), and mixed-type spells in 9.6% (n = 30). Sleep electroencephalograms were applied for all patients, 98.2% (n = 306) of which were …


The Effect Of Isotretinoin On Insulin Resistance And Adipocytokine Levels In Acne Vulgaris Patients, Gonca Soyuduru, Esra Özsoy Adişen, İlkay Özer, Ahmet Burhan Aksakal Jan 2019

The Effect Of Isotretinoin On Insulin Resistance And Adipocytokine Levels In Acne Vulgaris Patients, Gonca Soyuduru, Esra Özsoy Adişen, İlkay Özer, Ahmet Burhan Aksakal

Turkish Journal of Medical Sciences

Recent data draw attention to the effect of body composition, insulin resistance, and adipocytokines to acne vulgaris (AV) development. The aim of this study was to assess the association of AV with insulin resistance and adipocytokine levels and to evaluate the effect of isotretinoin on insulin resistance and adipocytokine levels. Materials and methods: In 29 AV patients and 29 healthy volunteers, body mass index (BMI) and body fat mass (BFM), lipid, adiponectin, leptin, resistin, retinol binding protein-4 (RBP4), and insulin levels were measured and insulin resistance was assessed by HOMA-IR index in serum samples taken twice from patients before and …


The Neutrophil-Lymphocyte Ratio And Its Relationship With Insulin Resistance In Obesity, Serdar Karakaya, Mustafa Altay, Fatma Kaplan Efe, İbrahi̇m Karadağ, Oktay Ünsal, Oktay Bulur, Murat Eser, Derun Taner Ertuğrul Jan 2019

The Neutrophil-Lymphocyte Ratio And Its Relationship With Insulin Resistance In Obesity, Serdar Karakaya, Mustafa Altay, Fatma Kaplan Efe, İbrahi̇m Karadağ, Oktay Ünsal, Oktay Bulur, Murat Eser, Derun Taner Ertuğrul

Turkish Journal of Medical Sciences

In this study, our aim was to investigate the neutrophil/lymphocyte (N/L) ratio, variations in leukocytes and leukocyte subtypes, and the relationship between N/L ratio and insulin resistance (IR) in obesity.Materials and methods: Ninety-six patients and 40 healthy controls were included in this study. Patients' blood glucose levels, insulin levels, and hemogram parameters upon 8 h of fasting were determined. Body mass index (BMI) and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) values were calculated.Results: Neutrophil numbers were found to be higher among obese patients with IR than among non-IR obese patients. The N/L ratio was, moreover, found to be higher among obese …


Evaluation Of The Efficacy Of Epiduroscopic Adhesiolysis In Failed Back Surgery Syndrome, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken Jan 2019

Evaluation Of The Efficacy Of Epiduroscopic Adhesiolysis In Failed Back Surgery Syndrome, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken

Turkish Journal of Medical Sciences

We aimed to compare the results of the treatment of the patients with failed back surgery syndrome (FBSS) by mechanical lysis and steroid hylase injection via epiduroscopy due to their stabilization status and to detect the effect of pathological diagnostic markers on prognosis and ongoing treatment protocol. Materials and methods: Eighty-two patients with FBSS symptoms were included. Two groups were composed as group I (stabilized) and group II (nonstabilized). All patients were evaluated using the oswestry disability index (ODI) and visual analogue scale (VAS) scores before and after treatment at 1, 3, 6, and 12 months and using the patient …


Does Chest Compression During Cardiopulmonary Resuscitation Provide Sufficient Cerebral Oxygenation?, Mehmet Aki̇f Yazar, Mehmet Bariş Açikgöz, Adnan Bayram Jan 2019

Does Chest Compression During Cardiopulmonary Resuscitation Provide Sufficient Cerebral Oxygenation?, Mehmet Aki̇f Yazar, Mehmet Bariş Açikgöz, Adnan Bayram

Turkish Journal of Medical Sciences

Background/aim: Some of the patients suffering from cardiac arrest (CA) remain in a chronic unconscious state in intensive care units (ICUs). The primary aim of this study was to evaluate the efficacy of chest compression (CC) on cerebral oxygenation during cardiopulmonary resuscitation (CPR). As a secondary goal, we attempted to determine the effects of regional cerebral oxygen saturation (rSO2) values on consciousness and the survival rate using the Full Outline of Unresponsiveness (FOUR) scoring method.Materials and methods: This observational preliminary study was carried out with 20 patients with CA who were hospitalized in ICUs. The rSO2 values measured by near-infrared …